CN103349766B - Pharmaceutical composition for endless postpartum lochia - Google Patents
Pharmaceutical composition for endless postpartum lochia Download PDFInfo
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- CN103349766B CN103349766B CN201310286380.5A CN201310286380A CN103349766B CN 103349766 B CN103349766 B CN 103349766B CN 201310286380 A CN201310286380 A CN 201310286380A CN 103349766 B CN103349766 B CN 103349766B
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Abstract
The invention relates to a pharmaceutical composition for endless postpartum lochia. The pharmaceutical composition comprises the following raw materials in parts by weight: 25 parts of leonurus japonicas, 25 parts of cortex albiziae, 20 parts of arillus longan, 20 parts of mulberries, 20 parts of red flowers, 19 parts of patrinia, 18 parts of yams, 18 parts of radix aucklandiae, 16 parts of poria cocos, 16 parts of baked ginger, 15 parts of pollen typhae, 15 parts of rhizoma cyperi, 15 parts of radix trichosanthis, 13 parts of golden cypress, 13 parts of medlar, 10 parts of fructus liquidambaris, 10 parts of pericarpium citri reticulatae, 10 parts of ligusticum wallichii, 8 parts of hawthorn, 8 parts of curcuma zedoary, 7 parts of cassia twigs, 5 parts of agarics, 4 parts of malt, 3 parts of cowherb seeds and 1 part of liquorice. The pharmaceutical composition has the effects of benefiting vital energy, nourishing blood, activating blood and removing stasis, is simple and convenient to prepare, wide in herbal source range and low in cost, and has a wide application prospect.
Description
Technical field
The invention belongs to Chinese medicine technical field, concrete, relate to a kind of pharmaceutical composition of Chinese herbal medicine as raw material treatment prolonged lochia of take.
Background technology
Prolonged lochia is also lochia, and lochia refers to after parturient childbirth, and the remaining blood that intrauterine is left over and turbid liquid, be not normal by QI-blood circulation, and stagnation of QI and blood causes.As < < tire, produce heart method > >, " lochia is more than, and non-as sudden profuse uterine bleeding sudden and violent time more than also.Owing to hindering its menses puerperal, deficient deficiency, can not receive and take the photograph, or stagnant blood is not to the utmost, the difficult peace of good blood, mutually and and under, with the passing of time more than ".Lochia is one of department of obstetrics and gynecology common clinical.With China birth rate, calculate, approximately have every year 40000000 women to experience birth process, the situation such as the interruption of pregnancy such as artificial abortion, induced labor in addition, patient group also can increase greatly.
The traditional Chinese medical science thinks, primary disease pathology is mainly that QI-blood circulation is not normal, stagnation of QI and blood.Face in disease and think that primary disease is the card of deficiency in origin and excess in superficiality in fact.Deficiency in origin is spleen and suffers from a deficiency of the kidney, the real blood stasis that is of mark.The pregnant foster born of the same parents' tire of married woman, needs to consume cloudy blood; During childbirth firmly, perspiration, maternal infuries is lost blood and postpartum breastfeeding increases the weight of again the loss of QI and blood; Deficiency of qi and blood, the debility of CHONG and REN meridians, this had been both married woman's special physiological state in puerperal, was also the cause of disease of the many void of puerperal disease, people's all day " all joints in puerpera being hollow and deficient " dies.If puerpera's kidney qi foot essence can activating QI hemopoietic, QI and blood biochemistry is inexhaustible for spleen health movement, and QI and blood is gradually prosperous, and the sea of blood gradually fills, and logical Sheng of conception vessel and uterus be from flourish, and blood is taken the photograph in contracting palace and lochia can be exhausted.If weakness of the spleen and stomach or vigour element is empty usually for married woman, multiple wound in gestation, childbirth, gas damages void that blood consumes spleen kidney more very.Dysfunction of the spleen in transportation QI and blood is biochemical deficient, has under one's command and haves no right; The angry blood of being difficult of damage of essence insufficiency of blood of suffering from a deficiency of the kidney moistens supports punching and appoints, and decline of the fire from the gate of life can not warm uterus; Puerpera consumes the QI and blood of wound and can not be taken a tonic or nourishing food to build up one's health in time, the debility of CHONG and REN meridians and cause lochia non-stop.Though appoint in punching the sick position of primary disease, uterus, changes in QI and blood, is originally deficiency of spleen and stomach, the real blood stasis that is of mark.Doctor trained in Western medicine thinks, its cause of disease is mainly uterus meromorphosis, when part Placenta Hominis, fetal membrane is residual or infect and affect uterine contraction and recovery; Or puerpera as suffered from chronic disease, severe loss of blood, excessively tired, body constitution fails to recover, or the local factor such as uterus excessive expansion, hysteromyoma, all can affect uterus meromorphosis.Secondly, after cesarean section, when Uterus wall disruption of wound, operation, hemostasis, thoroughly or because of postoperative infection, affect uterine involution and causes bleeding incessantly.
At present women's metrorrhagia in puerperal, lochia are mainly treated by Chinese medicine and two kinds of methods of Western medicine.Doctor trained in Western medicine generally adopts accelerates uterine contraction with hemostasis, and enrich blood, continue with antibiotic infection control etc., though through treatment energy relief of symptoms, have certain untoward reaction, therapeutic effect is not satisfactory, although can reach the effect of getting instant result when this disease for the treatment of, but toxic and side effects is larger when western medicine women metrorrhagia in puerperal, lochia disease, easily outbreak repeatedly, and can not fundamentally thoroughly cure this disease.China's traditional medicine utilizes treatment by Chinese herbs women metrorrhagia in puerperal, lochia disease to have a long history, Chinese medicine not only can reach the effect of rapid hemostasis, the more important thing is and can also carry out double recuperation to human body, thereby reach equilibrium between yin and yang, QI and blood is normally moved, reached the object of hemostasis.
Prior art prescriptions of Chinese medicine lacks dialectical, and treatment cycle is long, and suiting the medicine to the illness property is not strong, and curative effect is not obvious, even also can bring side effect to patient, increases patient suffering.
Summary of the invention
The object of this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, have no side effect, safe ready, cheap pure traditional Chinese compound medicine.
Motherland's medical science thinks, lochiorrhea pathology is mainly that QI-blood circulation is not normal, stagnation of QI and blood.Face in disease and think that primary disease is the card of deficiency in origin and excess in superficiality in fact.Deficiency in origin is spleen and suffers from a deficiency of the kidney, the real blood stasis that is of mark, present inventor puts into practice according to doctor's row for many years in conjunction with forefathers' secret recipe, by the research to Chinese medicine, and in conjunction with dialectical demonstration, in many ways collect the length of many families, seek therapeutic regimen, from motherland's medical treasure-house, filter out benefiting QI and nourishing blood, the invigorate blood circulation natural Chinese medicine of blood stasis expelling, by theory of Chinese medical science prescription, skim the cream off milk, in conjunction with Traditional Chinese Medicine technology, be meticulously mixed with the Chinese medicine composition for prolonged lochia of the present invention, pass through benefiting QI and nourishing blood, with respect to Western medicine, Chinese medicine of the present invention is rapid-action, effect is strong, short treating period, safe, without obvious toxic-side effects, medication is simple, can improve microcirculation, promote uterine myometrium, contribute to disappearing of endometrial renewal and inflammation, also can make in utero residual Placenta Hominis, fetal membrane is discharged automatically, remove the uterine cavity stasis of blood long-pending.
For achieving the above object, the technical solution used in the present invention is as follows:
For a pharmaceutical composition for prolonged lochia, its raw material by following weight proportioning is prepared and is obtained:
25 parts of Herba Leonuris, 25 parts of Cortex Albiziaes, 20 parts of Arillus Longans, 20 parts, Fructus Mori, 20 parts, Flos Carthami,
19 parts of Herba Patriniae, 18 parts of Rhizoma Dioscoreaes, 18 parts of the Radix Aucklandiae, 16 parts, Poria, 16 parts of Rhizoma Zingiberis Preparatums
15 parts of Pollen Typhaes, 15 parts of Rhizoma Cyperis, 15 parts of Radix Trichosanthis, 13 parts of Cortex Phellodendris, 13 parts of Fructus Lycii,
10 parts of Fructus Liquidambaris, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Chuanxiongs, 8 parts of Fructus Crataegis, 8 parts of Rhizoma Curcumae,
7 parts of Ramulus Cinnamomi, 5 parts, Auricularia, 4 parts, Fructus Hordei Germinatus, 3 parts of Semen Vaccariae, 1 part, Radix Glycyrrhizae.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get crude drug (proportioning unit: gram) mix homogeneously of above-mentioned parts by weight, concentratedly after being decocted in water for oral dose prepare capsule, concrete operations are:
1) take each crude drug, standby;
2) by step 1) in crude drug be soaked in water (water covers powder 2～3cm and is advisable) after 15～30 minutes, intense fire boils, 20～30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) by step 2) in resulting medicinal residues decoct with water, amount of water was not to have medicinal residues face 1～2cm, intense fire boils, 15～20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) merge twice filtrate and be condensed into the clear paste that density is 1.1-1.2g/ml, in 50-60 ℃ dry after, be ground into 100-120 object medicated powder, in incapsulating, sterilization makes capsule product, each oral 1 gram, twice on the one.
Function cures mainly: women's qi-deficiency type in puerperal lochiorrhea.Disease is seen: lochia, and dripping urine endlessly, does not with the passing of time heal, and color is light red, and amount is many, and matter is thin, odorless, continuous and dull pain in the abdomen, few abdomen tenesmus, breathes hard, tired mind, pale complexion is simple and unadorned, pale tongue, tongue is normal, a little less than moderate pulse.
The component of medicine of the present invention all adopts natural raw material of Chinese medicine, and its preparation is easy, and medicine source is extensive, with low cost, and it follows the prescriptions principle of the traditional Chinese medical science, and through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, has a extensive future.
The specific embodiment
Embodiment 1
For a pharmaceutical composition for prolonged lochia, its raw material by following weight proportioning is prepared and is obtained:
25 parts of Herba Leonuris, 25 parts of Cortex Albiziaes, 20 parts of Arillus Longans, 20 parts, Fructus Mori, 20 parts, Flos Carthami,
19 parts of Herba Patriniae, 18 parts of Rhizoma Dioscoreaes, 18 parts of the Radix Aucklandiae, 16 parts, Poria, 16 parts of Rhizoma Zingiberis Preparatums
15 parts of Pollen Typhaes, 15 parts of Rhizoma Cyperis, 15 parts of Radix Trichosanthis, 13 parts of Cortex Phellodendris, 13 parts of Fructus Lycii,
10 parts of Fructus Liquidambaris, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Chuanxiongs, 8 parts of Fructus Crataegis, 8 parts of Rhizoma Curcumae,
7 parts of Ramulus Cinnamomi, 5 parts, Auricularia, 4 parts, Fructus Hordei Germinatus, 3 parts of Semen Vaccariae, 1 part, Radix Glycyrrhizae.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get crude drug (proportioning unit: gram) mix homogeneously of above-mentioned parts by weight, concentratedly after being decocted in water for oral dose prepare capsule, concrete operations are:
1) take each crude drug, standby;
2) by step 1) in crude drug be soaked in water (water covers powder 2～3cm and is advisable) after 15～30 minutes, intense fire boils, 20～30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) by step 2) in resulting medicinal residues decoct with water, amount of water was not to have medicinal residues face 1～2cm, intense fire boils, 15～20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) merge twice filtrate and be condensed into the clear paste that density is 1.1-1.2g/ml, in 50-60 ℃ dry after, be ground into 100-120 object medicated powder, incapsulate in (1#), sterilization makes capsule product, each oral 1g, one day twice, a minute morning and evening took for twice, a course for the treatment of Monday.
Embodiment 2
Clinical efficacy is summed up:
General data, Chinese medicine of the present invention is applied to clinical observation 106 examples
One, diagnosis basis
According to the diagnostic criteria of < < People's Republic of China (PRC) Chinese medicine industry standard (ZY-T001.1-94) > > disease of tcm lochia, formulate.
13 weeks puerperal, above vagina still had hemorrhagely, measured morely, and color depth is red, and matter is sad sticky, has smelly oxious gas.
2, gynecologial examination uterus low-grade infection.
3, flushed face, dryness of the mouth and throat.Red tongue, tongue is few, deficient and thready pulse and counting.
Two, efficacy evaluation
According to < < People's Republic of China (PRC) Chinese medicine industry standard (ZY-T001.1-94) > > disease of tcm lochia criterion of therapeutical effect, formulate.
1 cures: vaginal hemorrhage stops, transference cure.
2 take a turn for the better: vaginal hemorrhage reduces, and symptom alleviates.
3 do not heal: symptom is without improvement.
Three, efficacy result analysis
From year January in July, 2011 to 2013, make a definite diagnosis altogether blood-heat type lochia patient 106 examples, minimum 21 years old of age, maximum 40 years old, natural labor 61 examples wherein, cesarean 45 examples, the course of disease is the longest 90 days, the shortest 22 days.Take 1 course for the treatment of of Chinese medicine composition of embodiment 1 preparation, cure 95 examples, cure rate 89.6%; 11 examples that take a turn for the better, 0 example more, total effective rate 100%.
Embodiment 3
Medicine of the present invention and commercially available puerpera's health drug effect contrast experiment;
Experimental group is taken embodiment 1 to 32 puerperas and is prepared capsule, every day 2 times, puerperal, serve on 5 days, and follow-up observation is 15 days continuously.Matched group 30 examples take CHANFUKANG KELI, and a 5g one day three times, carries out paired observation.Result: as shown in the table, be unfavorable for postpartum recovery or uncomfortable situation that experimental group occurred in puerperal reduce than matched group, unable, the hyperhidrosis aversion to wind time of breathing hard is significantly shorter than matched group, obviously reduces puerperal infection and promotes lactogenic; The lochia persistent period obviously shortens.
| ? | Experimental group | Matched group |
| The unable natural law of breathing hard | 6.06±1.15 | 8.33±1.48 |
| Hyperhidrosis aversion to wind natural law | 4.14±0.77 | 6.87±1.63 |
| Abdominal pain natural law | 6.77±1.31 | 9.21±1.25 |
| Lochia continuous days | 6.57±1.43 | 9.15±1.08 |
Embodiment 4
Model case
Cattle, main suit produces a boy baby in July, 2010,50 days puerperal lochia, weak from head to foot, color is light red, amount is many, rare, tasteless, the indistinct pain of abdomen, few abdomen tenesmus, breathes hard; Clinical symptoms: breathe hard, tired mind, pale complexion is simple and unadorned, pale tongue, tongue is normal, and a little less than moderate pulse, clinical diagnosis is: ' qi-deficiency type lochiorrhea in puerperal ', tell all medicines of stopping using, take medicine of the present invention and serve on after 4 days, vagina only has a small amount of light courageous and upright secretions, the indistinct pain of abdomen, breathes hard, few abdomen tenesmus transference cure, continue to take to a course for the treatment of, vaginal hemorrhage stops, and has rosy cheeks, body of the tongue is light red, and arteries and veins is gentle, and other symptom all disappears.
Wang certain, patient sees a doctor not to the utmost because lochia is dripping for 58 days.Patient's full-term normal delivery one girl baby, existing lochia is not stopped, and a small amount of clot of the dark red folder of color, changes sanitary towel every day 2～3 times, lower abdomen dull pain, the soreness of waist, constipation with dry stool, body of the tongue is partially red, the tip of the tongue has petechia, yellow and thin fur, thready and stringy pulse.Gynaecological examination: vagina is smooth, inside has a small amount of courageous and upright secretions, cervix uteri light, and uterus prosposition, bigger than normal, the light tenderness of palace body; Bilateral adnexa is not different from.B ultrasonic prompting; Endometrium 6mm.Dialectical is stagnation of blood stasis and heat, and lochia is taken the medicine of the embodiment of the present invention 1 preparation, and after medicine, second day vaginal hemorrhage amount increases, and accompanies internal film tissue in small, broken bits, and that afternoon, amount of bleeding reduced.Further consultation after 3 days, lower abdomen pain is alleviated, and stool is smooth, and vagina has a small amount of light courageous and upright secretions, then gives treatment 2 days, and after medicine, only, more, tongue arteries and veins is as usual for all diseases for blood, and gynaecological examination is not different from, and B ultrasonic check uterus adnexa is also not different from.
What more than enumerate is only best specific embodiment of the present invention.Obviously, the invention is not restricted to above embodiment, can also have many distortion.All distortion that those of ordinary skill in the art can directly derive or associate from content disclosed by the invention, all should think protection scope of the present invention.
The present invention makes compatibility mutually between the various compositions of pharmaceutical composition Chinese medicine of prolonged lochia, coordinate usefulness, with low cost, through clinical verification, lochia is had to good therapeutic effect, and in the applicant's medical practice for many years, the case number of healing is numerous, obtain good effect, have broad application prospects.
Claims (1)
1. for a pharmaceutical composition for prolonged lochia, its raw material by following weight proportioning is prepared and is obtained:
25 parts of Herba Leonuris, 25 parts of Cortex Albiziaes, 20 parts of Arillus Longans, 20 parts, Fructus Mori, 20 parts, Flos Carthami,
19 parts of Herba Patriniae, 18 parts of Rhizoma Dioscoreaes, 18 parts of the Radix Aucklandiae, 16 parts, Poria, 16 parts of Rhizoma Zingiberis Preparatums
15 parts of Pollen Typhaes, 15 parts of Rhizoma Cyperis, 15 parts of Radix Trichosanthis, 13 parts of Cortex Phellodendris, 13 parts of Fructus Lycii,
10 parts of Fructus Liquidambaris, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Chuanxiongs, 8 parts of Fructus Crataegis, 8 parts of Rhizoma Curcumae,
7 parts of Ramulus Cinnamomi, 5 parts, Auricularia, 4 parts, Fructus Hordei Germinatus, 3 parts of Semen Vaccariae, 1 part, Radix Glycyrrhizae.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751549B (en) * | 2014-01-24 | 2015-11-25 | 许海燕 | A kind of preparation method for the treatment of the medicament of postpartum lochiorrhea |
| CN103990083A (en) * | 2014-04-22 | 2014-08-20 | 安徽省太湖山中药饮片有限公司 | Traditional Chinese medicine composition for treating postpartum lochiorrhea |
| CN104721799B (en) * | 2015-04-13 | 2018-04-13 | 翔宇药业股份有限公司 | A kind of preparation process of drug particles for puerperal blood clot dispersing |
| CN104740582B (en) * | 2015-04-13 | 2018-04-13 | 翔宇药业股份有限公司 | It is a kind of for the pharmaceutical preparation of puerperal blood clot dispersing and its application and detection method |
| CN105816590A (en) * | 2016-05-28 | 2016-08-03 | 程敬云 | Capsule for treating prolonged lochia and preparing method |
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2013
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095610A (en) * | 1993-05-24 | 1994-11-30 | 潘世庆 | The pharmaceutical preparation Fubingkang of treatment, prevention gynecological diseases |
| CN1679839A (en) * | 2005-01-14 | 2005-10-12 | 王庆华 | Postpartum recuring particle |
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