CN103386102B - Pharmaceutical composition for curing postpartum bleeding and preparation method thereof - Google Patents
Pharmaceutical composition for curing postpartum bleeding and preparation method thereof Download PDFInfo
- Publication number
- CN103386102B CN103386102B CN201310286333.0A CN201310286333A CN103386102B CN 103386102 B CN103386102 B CN 103386102B CN 201310286333 A CN201310286333 A CN 201310286333A CN 103386102 B CN103386102 B CN 103386102B
- Authority
- CN
- China
- Prior art keywords
- parts
- fructus
- rhizoma
- pharmaceutical composition
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pharmaceutical composition for curing postpartum bleeding. The composition is composed of following raw materials in parts by weight: 25 parts of motherwort, 25 parts of longan aril, 20 parts of mulberry, 20 parts of safflower, 19 parts of patrinia herb, 18 parts of Chinese yam, 17 parts of banksia rose, 16 parts of poria cocos, 16 parts of quick fried ginger, 15 parts of barbat skullcap, 15 parts of cattail pollen, 15 parts of cyperus rotundus, 15 parts of trichosanthes root, 13 parts of phellodendron, 12 parts of wolfberry, 10 parts of dandelion, 10 parts of fructus liquidambaris, 10 parts of dried orange peel, 10 parts of bitter organe, 10 parts of ligusticum wallichii, 8 parts of haw, 8 parts of curcuma rhizome, 7 parts of magnolia cortex, 7 parts of cassia twig, 5 parts of edible fungus, 3 parts of malt, 3 parts of cowherb seed and 1 part of licorice. The pharmaceutical composite has the functions of reinforcing Qi, nourishing blood and promoting blood circulation to remove blood stasis, has the advantages of simple and convenient preparation, wide material resources and low cost, and has a vast application prospect.
Description
Technical field
The invention belongs to Chinese medicine technical field, concrete, relate to and a kind ofly take Chinese herbal medicine and be pharmaceutical composition of raw material treatment congestion in puerperal and preparation method thereof.
Background technology
Puerperal, congestion referred to metrorrhagia in puerperal, uterus meromorphosis, and prolonged lochia, the symptom such as vaginal hemorrhage after artificial abortion, lochia refers to after parturient childbirth, and the remaining blood that intrauterine is left over and turbid liquid are not normal by QI-blood circulation, and stagnation of QI and blood causes.As < < tire, produce heart method > >, " lochia is more than, and non-as sudden profuse uterine bleeding sudden and violent time more than also.Owing to hindering its menses puerperal, deficient deficiency, can not receive and take the photograph, or stagnant blood is not to the utmost, the difficult peace of good blood, mutually and and under, with the passing of time more than ".Lochia is one of department of obstetrics and gynecology common clinical.With China birth rate, calculate, approximately have every year 40000000 women to experience birth process, the situation such as the interruption of pregnancy such as artificial abortion, induced labor in addition, patient group also can increase greatly.
The traditional Chinese medical science thinks, primary disease pathology is mainly that QI-blood circulation is not normal, stagnation of QI and blood.Face in disease and think that primary disease is the card of deficiency in origin and excess in superficiality in fact.Deficiency in origin is spleen and suffers from a deficiency of the kidney, the real blood stasis that is of mark.The pregnant foster born of the same parents' tire of married woman, needs to consume cloudy blood; During childbirth firmly, perspiration, maternal infuries is lost blood and postpartum breastfeeding increases the weight of again the loss of QI and blood; Deficiency of qi and blood, the debility of CHONG and REN meridians, this had been both married woman's special physiological state in puerperal, was also the cause of disease of the many void of puerperal disease, people's all day " all joints in puerpera being hollow and deficient " dies.If puerpera's kidney qi foot essence can activating QI hemopoietic, QI and blood biochemistry is inexhaustible for spleen health movement, and QI and blood is gradually prosperous, and the sea of blood gradually fills, and logical Sheng of conception vessel and uterus be from flourish, and blood is taken the photograph in contracting palace and lochia can be exhausted.If weakness of the spleen and stomach or vigour element is empty usually for married woman, multiple wound in gestation, childbirth, gas damages void that blood consumes spleen kidney more very.Dysfunction of the spleen in transportation QI and blood is biochemical deficient, has under one's command and haves no right; The angry blood of being difficult of damage of essence insufficiency of blood of suffering from a deficiency of the kidney moistens supports punching and appoints, and decline of the fire from the gate of life can not warm uterus; Puerpera consumes the QI and blood of wound and can not be taken a tonic or nourishing food to build up one's health in time, the debility of CHONG and REN meridians and cause lochia non-stop.Though appoint in punching the sick position of primary disease, uterus, changes in QI and blood, is originally deficiency of spleen and stomach, the real blood stasis that is of mark.Doctor trained in Western medicine thinks, its cause of disease is mainly uterus meromorphosis, when part Placenta Hominis, fetal membrane is residual or infect and affect uterine contraction and recovery; Or puerpera as suffered from chronic disease, severe loss of blood, excessively tired, body constitution fails to recover, or the local factor such as uterus excessive expansion, hysteromyoma, all can affect uterus meromorphosis.Secondly, after cesarean section, when Uterus wall disruption of wound, operation, hemostasis, thoroughly or because of postoperative infection, affect uterine involution and causes bleeding incessantly.
At present women uterus in puerperal congestion, lochia are mainly treated by Chinese medicine and two kinds of methods of Western medicine.Doctor trained in Western medicine generally adopts accelerates uterine contraction with hemostasis, and enrich blood, continue with antibiotic infection control etc., though through treatment energy relief of symptoms, have certain untoward reaction, therapeutic effect is not satisfactory, although can reach the effect of getting instant result when this disease for the treatment of, but toxic and side effects is larger when western medicine women uterus in puerperal congestion, lochia disease, easily outbreak repeatedly, and can not fundamentally thoroughly cure this disease.China's traditional medicine utilizes treatment by Chinese herbs women uterus in puerperal congestion, lochia disease to have a long history, Chinese medicine not only can reach the effect of rapid hemostasis, the more important thing is and can also carry out double recuperation to human body, thereby reach equilibrium between yin and yang, QI and blood is normally moved, reached the object of hemostasis.
Prior art prescriptions of Chinese medicine lacks dialectical, and treatment cycle is long, and suiting the medicine to the illness property is not strong, and curative effect is not obvious, even also can bring side effect to patient, increases patient suffering.
Summary of the invention
The object of this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, have no side effect, safe ready, cheap pure traditional Chinese compound medicine.
Motherland's medical science thinks, puerperal, congestion pathology was mainly that QI-blood circulation is not normal, stagnation of QI and blood.Face in disease and think that primary disease is the card of deficiency in origin and excess in superficiality in fact.Deficiency in origin is spleen and suffers from a deficiency of the kidney, the real blood stasis that is of mark, present inventor puts into practice according to doctor's row for many years in conjunction with forefathers' secret recipe, by the research to Chinese medicine, and in conjunction with dialectical demonstration, in many ways collect the length of many families, seek therapeutic regimen, from motherland's medical treasure-house, filter out benefiting QI and nourishing blood, the invigorate blood circulation natural Chinese medicine of blood stasis expelling, by theory of Chinese medical science prescription, skim the cream off milk, in conjunction with Traditional Chinese Medicine technology, be meticulously mixed with the Chinese medicine composition for congestion in puerperal of the present invention, pass through benefiting QI and nourishing blood, with respect to Western medicine, Chinese medicine of the present invention is rapid-action, effect is strong, short treating period, safe, without obvious toxic-side effects, medication is simple, can improve microcirculation, promote uterine myometrium, contribute to disappearing of endometrial renewal and inflammation, also can make in utero residual Placenta Hominis, fetal membrane is discharged automatically, remove the uterine cavity stasis of blood long-pending.
For achieving the above object, the technical solution used in the present invention is as follows:
For a pharmaceutical composition for congestion in puerperal, its raw material by following weight proportioning is prepared and is obtained:
25 parts of Herba Leonuris, 25 parts of Arillus Longans, 20 parts, Fructus Mori, 20 parts, Flos Carthami, 19 parts of Herba Patriniae,
18 parts of Rhizoma Dioscoreaes, 17 parts of the Radix Aucklandiae, 16 parts, Poria, 16 parts of Rhizoma Zingiberis Preparatums, 15 parts of Herba Scutellariae Barbataes,
15 parts of Pollen Typhaes, 15 parts of Rhizoma Cyperis, 15 parts of Radix Trichosanthis, 13 parts of Cortex Phellodendris, 12 parts of Fructus Lycii,
10 parts of Herba Taraxacis, 10 parts of Fructus Liquidambaris, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Fructus Aurantiis, 10 parts of Rhizoma Chuanxiongs,
8 parts of Fructus Crataegis, 8 parts of Rhizoma Curcumae, 7 parts of Cortex Magnoliae Officinalis, 7 parts of Ramulus Cinnamomi, 5 parts, Auricularia,
3 parts, Fructus Hordei Germinatus, 3 parts of Semen Vaccariae, 1 part, Radix Glycyrrhizae.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get crude drug (proportioning unit: gram) mix homogeneously of above-mentioned parts by weight, concentratedly after being decocted in water for oral dose prepare capsule, concrete operations are:
1) take each crude drug, standby;
2) by step 1) in crude drug be soaked in water (water covers powder 2～3cm and is advisable) after 15～30 minutes, intense fire boils, 20～30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) by step 2) in resulting medicinal residues decoct with water, amount of water was not to have medicinal residues face 1～2cm, intense fire boils, 15～20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) merge twice filtrate and be condensed into the clear paste that density is 1.1-1.2g/m1, in 50-60 ℃ dry after, be ground into 100-120 object medicated powder, in incapsulating, sterilization makes capsule product, each oral 1g, twice on the one.
Function cures mainly: women's deficiency of vital energy in puerperal congestion, lochiorrhea.Disease is seen: lochia, and dripping urine endlessly, does not with the passing of time heal, and color is light red, and amount is many, and matter is thin, odorless, continuous and dull pain in the abdomen, few abdomen tenesmus, breathes hard, tired mind, pale complexion is simple and unadorned, pale tongue, tongue is normal, a little less than moderate pulse.
The component of medicine of the present invention all adopts natural raw material of Chinese medicine, and its preparation is easy, and medicine source is extensive, with low cost, and it follows the prescriptions principle of the traditional Chinese medical science, and through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, has a extensive future.
The specific embodiment
Embodiment 1
25 parts of Herba Leonuris, 25 parts of Arillus Longans, 20 parts, Fructus Mori, 20 parts, Flos Carthami, 19 parts of Herba Patriniae,
18 parts of Rhizoma Dioscoreaes, 17 parts of the Radix Aucklandiae, 16 parts, Poria, 16 parts of Rhizoma Zingiberis Preparatums, 15 parts of Herba Scutellariae Barbataes,
15 parts of Pollen Typhaes, 15 parts of Rhizoma Cyperis, 15 parts of Radix Trichosanthis, 13 parts of Cortex Phellodendris, 12 parts of Fructus Lycii,
10 parts of Herba Taraxacis, 10 parts of Fructus Liquidambaris, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Fructus Aurantiis, 10 parts of Rhizoma Chuanxiongs,
8 parts of Fructus Crataegis, 8 parts of Rhizoma Curcumae, 7 parts of Cortex Magnoliae Officinalis, 7 parts of Ramulus Cinnamomi, 5 parts, Auricularia,
3 parts, Fructus Hordei Germinatus, 3 parts of Semen Vaccariae, 1 part, Radix Glycyrrhizae.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get crude drug (proportioning unit: gram) mix homogeneously of above-mentioned parts by weight, concentratedly after being decocted in water for oral dose prepare capsule, concrete operations are:
1) take each crude drug, standby;
2) by step 1) in crude drug be soaked in water (water covers powder 3cm and is advisable) after 30 minutes, intense fire boils, 30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) by step 2) in resulting medicinal residues decoct with water, amount of water was not to have medicinal residues face 2cm, intense fire boils, 20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) merge twice filtrate and be condensed into the clear paste that density is 1.2g/m1, in 60 ℃ dry after, be ground into 120 object medicated powder, incapsulate in (1#), sterilization makes capsule product, each oral 3, one day twice, a minute morning and evening took for twice, a course for the treatment of Monday.
Embodiment 2
Clinical data; Medicine of the present invention and commercially available puerpera's health drug effect contrast experiment;
Experimental group is taken embodiment 1 to 50 puerperas and is prepared capsule, every day 2 times, puerperal, serve on 5 days, and follow-up observation is 15 days continuously.Matched group 47 examples take CHANFUKANG KELI, and a 5g one day three times, carries out paired observation.Result: as shown in the table, be unfavorable for postpartum recovery or uncomfortable situation that experimental group occurred in puerperal reduce than matched group, unable, the hyperhidrosis aversion to wind time of breathing hard is significantly shorter than matched group, obviously reduces puerperal infection and promotes lactogenic; The lochia persistent period obviously shortens.
| ? | Experimental group | Matched group |
| The unable natural law of breathing hard | 6.12±1.67 | 8.27±1.04 |
| Hyperhidrosis aversion to wind natural law | 4.25±1.15 | 6.93±1.27 |
| Abdominal pain natural law | 6.81±1.27 | 9.24±1.05 |
| Lochia continuous days | 6.31±1.28 | 9.82±1.36 |
According to traditional Chinese medical science standard, observe body of the tongue and pulse condition, understand physiological function situation in puerperal
Mammary gland and galactopoiesis situation: two groups all occur without mastitis.Galactopoiesis amount experimental group from second and third day taking medicine significantly increases compared with matched group.
Embodiment 3
Model case
Chen, 32 years old, because postpartum vaginal haemophilia is gone to a doctor for more than 80 day.In normal labor on February 3 one boy baby in 2011, postpartum vaginal haemophilia, color is red or dim red, has large clot, the lower abdominal pain at most of bleeding, after large clot flows out, stomachache is slightly alleviated.Food receive still can, two just self-regulateds.Bad during by western medicine fashion, give pharmaceutical composition prepared by the embodiment of the present invention 1, take after 1 course for the treatment of, vaginal hemorrhage is stopped, only has a little pink colour leucorrhea, transference cure, spirit is fair.Continue to take after 1 course for the treatment of, only, abdominal pain disappears vaginal hemorrhage, and ill symptoms disappears, and follows up a case by regular visits to without ill symptoms, without recurrence.
High certain, 35 years old, puerpera's the 4th tire full-term normal delivery (drug-induced abortion's 3 tires), 42 days postpartum lochiorrhea, color secretly has piece, waist ventral spine pain, dizzy cardiopalmus, tongue is dim, stringy and hesitant pulse.Ultrasound diagnosis: metrauxe, return to the past bad.Routine blood test: anemia.Once clothes in, Western medicine, curative effect is not good enough.Take a course for the treatment of of pharmaceutical composition of the present invention, abdominal pain disappears, and vaginal hemorrhage stops, and more, tongue arteries and veins is as usual for all diseases, and gynaecological examination and B ultrasonic check uterus adnexa are not different from, follow up a case by regular visits to without recurrence.
Between the various compositions of pharmaceutical composition Chinese medicine of the present invention for congestion in puerperal, make mutually compatibility, coordinate usefulness, with low cost, through clinical verification, lochia is had to good therapeutic effect, and in the applicant's medical practice for many years, the case number of healing is numerous, obtain good effect, have broad application prospects.
What more than enumerate is only best specific embodiment of the present invention.Obviously, the invention is not restricted to above embodiment, can also have many distortion.All distortion that those of ordinary skill in the art can directly derive or associate from content disclosed by the invention, all should think protection scope of the present invention.
Claims (1)
1. for a pharmaceutical composition for congestion in puerperal, its crude drug by following weight parts is prepared and is obtained:
25 parts of Herba Leonuris, 25 parts of Arillus Longans, 20 parts, Fructus Mori, 20 parts, Flos Carthami, 19 parts of Herba Patriniae,
18 parts of Rhizoma Dioscoreaes, 17 parts of the Radix Aucklandiae, 16 parts, Poria, 16 parts of Rhizoma Zingiberis Preparatums, 15 parts of Herba Scutellariae Barbataes,
15 parts of Pollen Typhaes, 15 parts of Rhizoma Cyperis, 15 parts of Radix Trichosanthis, 13 parts of Cortex Phellodendris, 12 parts of Fructus Lycii,
10 parts of Herba Taraxacis, 10 parts of Fructus Liquidambaris, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Fructus Aurantiis, 10 parts of Rhizoma Chuanxiongs,
8 parts of Fructus Crataegis, 8 parts of Rhizoma Curcumae, 7 parts of Cortex Magnoliae Officinalis, 7 parts of Ramulus Cinnamomi, 5 parts, Auricularia,
3 parts, Fructus Hordei Germinatus, 3 parts of Semen Vaccariae, 1 part, Radix Glycyrrhizae;
The preparation method of described pharmaceutical composition comprises the steps:
1) according to weight portion, take each crude drug, standby;
2) by step 1) in crude drug be soaked in water after 15～30 minutes, intense fire boils, 20～30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) by step 2) in resulting medicinal residues decoct with water, amount of water was not to have medicinal residues face 1～2cm, intense fire boils, 15～20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) merge twice filtrate, be condensed into the clear paste that density is 1.1-1.2g/ml, in 50-60 ℃ dry after, be ground into 100-120 object medicated powder, in incapsulating, obtain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310286333.0A CN103386102B (en) | 2013-07-08 | 2013-07-08 | Pharmaceutical composition for curing postpartum bleeding and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310286333.0A CN103386102B (en) | 2013-07-08 | 2013-07-08 | Pharmaceutical composition for curing postpartum bleeding and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103386102A CN103386102A (en) | 2013-11-13 |
| CN103386102B true CN103386102B (en) | 2014-11-26 |
Family
ID=49530636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310286333.0A Expired - Fee Related CN103386102B (en) | 2013-07-08 | 2013-07-08 | Pharmaceutical composition for curing postpartum bleeding and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103386102B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491219B (en) * | 2014-12-12 | 2018-07-17 | 信阳农林学院 | A kind of herb liquid and preparation method thereof of prevention and treatment dam endometritis |
| CN104721799B (en) * | 2015-04-13 | 2018-04-13 | 翔宇药业股份有限公司 | A kind of preparation process of drug particles for puerperal blood clot dispersing |
| CN104740582B (en) * | 2015-04-13 | 2018-04-13 | 翔宇药业股份有限公司 | It is a kind of for the pharmaceutical preparation of puerperal blood clot dispersing and its application and detection method |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1061854C (en) * | 1993-05-24 | 2001-02-14 | 潘世庆 | Medicinal preparation for treatment and prevention of gynopathy |
| CN101049472A (en) * | 2007-05-16 | 2007-10-10 | 北京艺信堂医药研究所 | Preparation of Chinese traditional medicine for treating barrenness caused by endometriosis |
| CN101129897A (en) * | 2007-09-24 | 2008-02-27 | 北京艺信堂医药研究所 | Proprietary Chinese medicine for treating endometritis |
| CN101596247A (en) * | 2009-01-21 | 2009-12-09 | 曹莹莹 | Treatment causes the Chinese medicine medicated wine of infertility because of obstruction of fallopian tube |
| CN103127460B (en) * | 2013-02-16 | 2014-12-10 | 河南科技大学 | Traditional Chinese medicine composition for curing gynecologic inflammation and preparation method thereof |
-
2013
- 2013-07-08 CN CN201310286333.0A patent/CN103386102B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN103386102A (en) | 2013-11-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103585378B (en) | A Chinese medicinal composition for treating female infertility, and its preparation method | |
| CN103638511B (en) | Puerperal blood clot dispersing granule | |
| CN102068641A (en) | Chinese medicinal capsules for treating gynecological diseases | |
| CN103349766B (en) | Pharmaceutical composition for endless postpartum lochia | |
| CN102836409B (en) | Traditional Chinese medicine for treating postpartum lochiorrhea and preparation method | |
| CN104208554A (en) | Traditional Chinese medicine mainly for treating multiple female diseases | |
| CN115518116A (en) | Abdomen patch for preventing and treating intrauterine adhesion and preparation method thereof | |
| CN103386102B (en) | Pharmaceutical composition for curing postpartum bleeding and preparation method thereof | |
| CN104147314B (en) | Traditional Chinese medicine preparation for treating postpartum hemorrhage and preparation method | |
| CN102526594B (en) | Traditional Chinese medicine preparation for treating pregnancy reaction | |
| CN105944020B (en) | Traditional Chinese medicine for treating ovarian function decline | |
| CN103990058A (en) | Menstruation promoting and vigor keeping paste | |
| CN102755491B (en) | Chinese medicinal composition for treating threatened abortion | |
| CN104740582B (en) | It is a kind of for the pharmaceutical preparation of puerperal blood clot dispersing and its application and detection method | |
| CN104547396A (en) | Traditional Chinese medicinal composition for treating delayed menstrual cycle | |
| CN104117018A (en) | Traditional Chinese medicine composition for treating coronary heart disease | |
| CN104056173A (en) | Traditional Chinese medicine composition for treating qi and blood deficiency of pregnant women in gestation period | |
| CN104721799B (en) | A kind of preparation process of drug particles for puerperal blood clot dispersing | |
| CN102755518A (en) | Medicinal prescription for treating recurrent abortion | |
| CN103041017B (en) | Traditional Chinese medicine preparation for treating functional uterine bleeding and preparation method thereof | |
| CN105232971A (en) | Traditional Chinese medicine composition for treating metrorrhagia and metrostaxis with kidney yin deficiency symptom | |
| CN105535719A (en) | Medicine composition for treating blood stasis type amenorrhoea | |
| CN105395768A (en) | Pharmaceutical composition for treating qi-blood deficiency type hypomenorrhea | |
| CN106309980B (en) | A kind of tocolytic agent and preparation method thereof | |
| CN105267836A (en) | Traditional Chinese medicine for treating coronary heart disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141126 Termination date: 20150708 |
|
| EXPY | Termination of patent right or utility model |