CN104352867A - Traditional Chinese medicine composition for treating gestational depression - Google Patents

Abstract

The invention provides a traditional Chinese medicine composition for treating gestational depression. The composition is prepared from the following raw materials: rhizoma cyperi, codonopsis pilosula, astragalus membranaceus, rhizoma atractylodis macrocephalae, eucommia ulmoides, herba taxilli, semen cuscutae, cortex albiziae, tuber fleeceflower stem, radix pseudostellariae, jujube kernel, radix ophiopogonis, Huai wheat, radix gentianae, chrysanthemum and licorice root. The composition for treating gestational depression is provided against the depression symptom during the gestation period by combining modern traditional Chinese medical theory. According to the combining prescription of monarch, minister, assistant and guide drugs, the effect of a single medicinal material and the effects of the prescription can be played. Years of clinical tests prove that the composition is suitable for treatment on depression in each phase of gestation, does not have toxic or side effect on a fetus, does not influence normal development of the fetus, has good effects of nourishing blood and yin, invigorating spleen, supplementing qi, nourishing heart, tranquilizing, promoting qi circulation, relieving depression, and nourishing kidneys for preventing miscarriage, has the advantages of exact drug effect, quick response, no toxic or side effect and the like, and is worthy of clinical popularization.

Description

A kind of Chinese medicine composition for the treatment of trimester of pregnancy depression

Technical field

The invention belongs to medical art, in particular to a kind of Chinese medicine composition for the treatment of trimester of pregnancy depression.

Background technology

In During Pregnancy, the significant change of anemia of pregnant woman's hormone in vivo level, can affect in brain the change of the neurotransmitter regulating emotion.Under the effect of progestogen, anemia of pregnant woman occurs that the probability of various psychological problems and dysthymic disorder increases.The anemia of pregnant woman of nearly 50% has depressive symptom, often occurs inappetence, anxiety, Somatic discomfort sense and sleep disorder etc.

Trimester of pregnancy, depression may cause the situation such as habitual abortion, preeclampsia, premature labor, fetal distress, premature rupture of fetal membrane.Depression causes inappetence and sleep disorder can affect the absorption of anemia of pregnant woman to nutrition, causes fetal intrauterine growth retardation.Trimester of pregnancy the spiritual hypertonicity that causes as scaring, frightened, sad or other reasons of unhealthy emotion, the equilibrium relation between cerebral cortex and internal organs can be made lack of proper care, cause circulatory function disorder, cause placental abruption, even cause foetal death.Trimester of pregnancy, depression probably developed into postpartum depression, was all danger signal to family and child.

The traditional Chinese medical science is thought, trimester of pregnancy fetus need the QI and blood of mother to nourish, thus parent QI and blood relative deficiency, and the traditional Chinese medical science is thought, there is nausea and vomiting in the pregnancy period, if exaggerate, impairment of YIN, blood pertaining to YIN, cloudyly loses insufficiency of blood.The traditional Chinese medical science thinks hyperactivity of YANG due to deficiency of YIN, the raw interior-heat of the deficiency of YIN, cloudyly loses hyperactivity of fire, and blood deficiency does not nourish heart, and blood deficiency heart-fire is prosperous, and hyperactivity of fire is superior, above disturbs key (head) clearly, thus occurs depressed symptom.

In prior art, anti-depressant therapy remains the essential therapeutic arsenals of depression, but onset is the greatest drawback of current antidepressants slowly.Most patients with depression wishes that symptom can be alleviated rapidly after taking antidepressants, but the onset time of the antidepressants used at present generally all needed for 2-4 weeks, and some novel antidepressant such as escitalopram oxalates etc. take onset in 7-10 days at the soonest.Although at present some novel antidepressant were not definitely avoided trimester of pregnancy, the side reactions such as its gastrointestinal tract are more common, and have and report that it has the risk increasing neonatal pulmonary hypertension, therefore should careful application.

Summary of the invention

The object of the invention is for trimester of pregnancy depression treatment a kind of Chinese medicine composition is provided, be applicable to pregnancy early, in, late period depression treatment, and fetus is had no side effect, do not affect normal fetal and grow, in order to effectively to overcome the above-mentioned drawback existing for prior art.Chinese medicine composition of the present invention selects natural Chinese medicines raw material, verify through clinical trial for many years, there is effect of yin nourishing of well enriching blood, invigorating the spleen and benefiting QI, tranquilizing by nourishing the heart, promoting QI circulation for relieving depression, tonifying kidney for preventing miscarriage, for trimester of pregnancy depression, there is good effect, there is drug effect definite, instant effect, the advantage such as have no side effect.

In order to realize object of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of trimester of pregnancy depression, it is made up according to parts by weight of following raw materials according:

Rhizoma Cyperi 30-60 part, Radix Codonopsis 30-60 part, Radix Astragali 20-40 part, Rhizoma Atractylodis Macrocephalae 20-40 part, Cortex Eucommiae 20-40 part, Herba Taxilli 30-50 part, Semen Cuscutae 30-50 part, Cortex Albiziae 15-30 part, Caulis Polygoni Multiflori 15-30 part, Radix Pseudostellariae 15-30 part, Semen Ziziphi Spinosae 10-30 part, Radix Ophiopogonis 20-40 part, Huai wheat 20-40 part, Plumula Nelumbinis 20-40 part, Flos Chrysanthemi 20-40 part, Radix Glycyrrhizae 20-40 part.

Preferably, Chinese medicine composition of the present invention is the medicament be made up according to parts by weight of following raw materials according:

Rhizoma Cyperi 40-60 part, Radix Codonopsis 40-60 part, Radix Astragali 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Cortex Eucommiae 25-35 part, Herba Taxilli 35-45 part, Semen Cuscutae 35-45 part, Cortex Albiziae 20-30 part, Caulis Polygoni Multiflori 20-30 part, Radix Pseudostellariae 20-30 part, Semen Ziziphi Spinosae 15-25 part, Radix Ophiopogonis 25-35 part, Huai wheat 25-35 part, Plumula Nelumbinis 25-35 part, Flos Chrysanthemi 25-35 part, Radix Glycyrrhizae 25-35 part.

Prescription analysis of effective component of the present invention and monarch, minister, help, make relation as follows.

1. monarch drug: Rhizoma Cyperi, Radix Codonopsis are our monarch drug, main regulating functional activities of qi, resolving depression of regulating the flow of vital energy, antiabortive, eliminate depressed all diseases.

Rhizoma Cyperi: property is put down, and sweet in the mouth, is slightly cold.Enter lung, liver, spleen, stomach four warp.There are resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving, antiabortive effect.Compendium of Material Medica is carried " gas of Rhizoma Cyperi is flat and do not tremble with fear, fragrant and can alter, and how pungent its taste is can fall apart, and micro-hardship can be fallen, micro-sweet energy with ".Rhizoma Cyperi is the medicine of cloudy Liver Channel, the few sun of hands three burnt edema caused by disorder of QI of fainting, and holds concurrently logical 12 through edema caused by disorder of QI, therefore has dispersing the stagnated live-QI to relieve the stagnation of QI, the merit of regulating functional activities of qi." book on Chinese herbal medicine is looked for the truth " is said " Rhizoma Cyperi, arduous dry, enter liver and gall two through dissipating depression of QI ".Therefore Rhizoma Cyperi is monarch drug, we mainly play regulating functional activities of qi, resolving depression of regulating the flow of vital energy, antiabortive effect.

Radix Codonopsis: property is put down, sweet in the mouth, micro-acid.Return spleen, lung meridian.Can invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Radix Codonopsis is the key medicine of air making-up and spleen enlivening, and contained saponin, inulin, Alkaloid, starch etc. have strong effect in various degree to human body multi viscera, can improve the adaptability of human body.Work in coordination with regulating functional activities of qi with Rhizoma Cyperi, resolving depression of regulating the flow of vital energy.

2. ministerial drug: the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Herba Taxilli, Semen Cuscutae six medicine be auxiliary monarch drug Rhizoma Cyperi, Radix Codonopsis regulating functional activities of qi, resolving depression of regulating the flow of vital energy, the solid tire of spleen invigorating jointly, and other double diseases that the depression that disappears causes.

The Radix Astragali: property is put down, sweet in the mouth, tepor.Return lung, spleen, liver, kidney channel.Can invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.

The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Can invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Modern study shows Rhizoma Atractylodis Macrocephalae alcohol extract and ligroin extraction to unpregnancy mice isolated uterine Spontaneous Contraction and the uteri excitation that causes oxytocin, Herba Leonuri all in remarkable inhibitory action, and presents dose-effect relationship.

The Cortex Eucommiae: sweet in the mouth, warm in nature.There are liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, admittedly through antiabortive effect.Can treat the lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes, born of the same parents' tire that deficiency of liver-QI causes is not solid, the diseases such as scrotum pruritus due to damp pathogen.The Cortex Eucommiae that shows modern study can suppress isolated rat uterus to shrink, and has the effect that anti-lobus posterior hypophyseos shrinks uterus, has anti-abortional effect to the pregnant mice miscarriage caused by lobus posterior hypophyseos.

Herba Taxilli: property is put down, bitter in the mouth.Return liver, kidney channel.There is wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, the effect of antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and metrorrhagia is through many, and blood leaking in gestation, frequent fetal movement, has a dizzy spell.

Semen Cuscutae: acrid in the mouth, sweet, slightly warm in nature; Return liver,kidney,spleen warp; Gas and property are delayed, and can float and can sink.There is the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, effect of the solid tire of spleen invigorating.Cure mainly lumbago tinnitus, impotence and seminal emission, quench one's thirst, sterile, enuresis incontinence, stranguria with turbid discharge leukorrhagia, the head is dim, and lack of appetite is had loose bowels, frequent fetal movement.Modern pharmacological research finds can promote hypothalamus-hypophysis-gonad axis function as the principle active component Semen Cuscutae flavonoid of Semen Cuscutae, improves hypophysis to the reactivity of gonadotropin releasing hormone, improves the level of stress rats estradiol, Progesterone.

3. adjuvant drug: Cortex Albiziae, Caulis Polygoni Multiflori, Radix Pseudostellariae, Semen Ziziphi Spinosae, Radix Ophiopogonis, Huai wheat, Plumula Nelumbinis, Flos Chrysanthemi are all adjuvant drug, auxiliary the monarch and his subjects will play effect, and restrict that the monarch and his subjects' medicine is scorching, the fraud of impairment of YIN, play all medications effect simultaneously, treat many double diseases.

Cortex Albiziae: property is put down, sweet in the mouth.There is the merit of resolving depression and blood, mind calming, subduing inflammation.There is the effect controlling irritability, melancholy, insomnia, lung abscess, carbuncle, scrofula, injured bone.

Caulis Polygoni Multiflori: property is put down, sweet in the mouth, micro-hardship.Nourish heart, calm the nerves, dredging collateral, the effect of dispeling the wind.

Radix Pseudostellariae: sweet in the mouth, micro-hardship, tepor.Return lung, spleen channel.Strengthening spleen and lung can be mended, supplementing QI for promoting the production of body fluid.Main weakness of the spleen and stomach, inappetence, lassitude, impairment of both QI and YIN, dry cough expectorant is few, and spontaneous perspiration is breathed hard, and the convalescent stage of febrile disease deficiency of vital energy Tianjin is hindered, interior-heat is thirsty, or neurasthenia, and palpitation and insomnia is dizzy forgetful, Infantile Summer Fever.

Semen Ziziphi Spinosae: property is put down, sweet in the mouth, micro-acid.Can conscience be nourished, calm the nerves, arresting sweating.

Radix Ophiopogonis: sweet in the mouth, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.There is YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.

Huai wheat: property is put down, and sweet in the mouth, enters heart channel.There is the function of tranquilizing by nourishing the heart, clinically, be usually used in mind not peaceful, the diseases such as insomnia.

Plumula Nelumbinis: nature and flavor are bitter, cold.Clear away heart-fire, reduce phlegm and internal heat, hemostasis, arresting seminal emission.Can control vexed, thirsty, spit blood, seminal emission, can gentle QI of five ZANG-organs.

Flos Chrysanthemi: sweet in the mouth, micro-hardship, cold nature.Return lung, Liver Channel.Can to fall apart wind heat clearing away, suppressing the hyperactive liver improving eyesight.

4. make medicine: Radix Glycyrrhizae is for making medicine, and in the side of leading, all medicines arrive disease institute, and energy coordinating the actions of various ingredients in a prescription, Coordinated Play effect.

Radix Glycyrrhizae: can invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, can cushion toxicity, strong.

The present invention adopts natural pure Chinese herbal medicine reasonable formula, compatibility science.All medicines share, and multiple medicines cooperation has the advantages that composition is many, effect link is many, all medicine coordinative roles, all linked with one another, jointly reaches the effect of yin nourishing of enriching blood, invigorating the spleen and benefiting QI, tranquilizing by nourishing the heart, promoting QI circulation for relieving depression, tonifying kidney for preventing miscarriage.

Record and clinical verification through pharmacopeia, Radix Codonopsis and the Rhizoma Atractylodis Macrocephalae, the same use of Radix Glycyrrhizae, can invigorating the spleen and benefiting QI.Radix Codonopsis is helped mutually with the Rhizoma Atractylodis Macrocephalae, Herba Taxilli etc., can control insufficiency of the spleen frequent fetal movement, and the effect that spleen invigorating is antiabortive is played in retardation of growth of fetus habitual abortion.The Radix Astragali and Rhizoma Atractylodis Macrocephalae compatibility have good effect to the weak caused spontaneous perspiration of body void table.The Radix Astragali and Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae etc. share, can the edema that causes for the treatment of acute and chronic nephritis.Radix Pseudostellariae and Semen Ziziphi Spinosae compatibility, can control cardiopalmus sleeplessness, deficiency-heat hyperhidrosis etc. that deficiency of both QI and YIN causes.Huai wheat and the same use of the medicine such as Radix Glycyrrhizae Preparata, Fructus Jujubae, can nourish heart and allay excitement, cure mainly the disease of the malaise such as abnormal mind and uneasy sleeping at night.The compatibility such as Herba Taxilli and Semen Cuscutae, loses for Liver and kidney void, vaginal bleeding during pregnancy hematochezia, frequent fetal movement caused by the debility of CHONG and REN meridians, has invigorating the liver and kidney and the effect of nourishing blood and preventing abortion of holding concurrently.The compatibilities such as Semen Cuscutae and the Radix Astragali, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, can QI invigorating, spleen invigorating, antidiarrheal.

Detailed description of the invention:

Following examples further describe preparation process of the present invention and beneficial effect; embodiment is only for the object of illustration; do not limit the scope of the invention, the simultaneously apparent change made according to the present invention of those of ordinary skill in the art and modification are also contained within the scope of the invention.

Embodiment 1

Get Rhizoma Cyperi 60 grams, Radix Codonopsis 60 grams, the Radix Astragali 40 grams, the Rhizoma Atractylodis Macrocephalae 40 grams, the Cortex Eucommiae 40 grams, Herba Taxilli 50 grams, Semen Cuscutae 50 grams, Cortex Albiziae 30 grams, Caulis Polygoni Multiflori 30 grams, Radix Pseudostellariae 30 grams, Semen Ziziphi Spinosae 30 pieces, Radix Ophiopogonis 40 grams, Huai wheat 40 grams, Plumula Nelumbinis 40 grams, Flos Chrysanthemi 40 grams, 40 grams, Radix Glycyrrhizae.Medicinal 3000 ml waters in above-mentioned are put and soaks 45 minutes in a reservoir, put on slow fire and decoct 60 minutes, take out medicinal liquid; Put into 1500 ml waters in a reservoir again, put on slow fire and decoct 45 minutes, take out medicinal liquid.By twice fried medicinal liquid mixing, mix homogeneously, by every agent 40 milliliters, each 1 dose, respectively takes 1 time sooner or later.

embodiment 2

Get Rhizoma Cyperi 50 grams, Radix Codonopsis 50 grams, the Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, the Cortex Eucommiae 30 grams, Herba Taxilli 40 grams, Semen Cuscutae 40 grams, Cortex Albiziae 25 grams, Caulis Polygoni Multiflori 25 grams, Radix Pseudostellariae 25 grams, Semen Ziziphi Spinosae 20 pieces, Radix Ophiopogonis 30 grams, Huai wheat 30 grams, Plumula Nelumbinis 30 grams, Flos Chrysanthemi 30 grams, 30 grams, Radix Glycyrrhizae.Medicinal 2500 ml waters in above-mentioned are put and soaks 45 minutes in a reservoir, put on slow fire and decoct 50 minutes, take out medicinal liquid; Put into 1200 ml waters in a reservoir again, put on slow fire and decoct 35 minutes, take out medicinal liquid.By twice fried medicinal liquid mixing, mix homogeneously, by every agent 35 milliliters, each 1 dose, respectively takes 1 time sooner or later.

embodiment 3

Get Rhizoma Cyperi 40 grams, Radix Codonopsis 40 grams, the Radix Astragali 25 grams, the Rhizoma Atractylodis Macrocephalae 25 grams, the Cortex Eucommiae 25 grams, Herba Taxilli 35 grams, Semen Cuscutae 35 grams, Cortex Albiziae 20 grams, Caulis Polygoni Multiflori 20 grams, Radix Pseudostellariae 20 grams, Semen Ziziphi Spinosae 15 pieces, Radix Ophiopogonis 25 grams, Huai wheat 25 grams, Plumula Nelumbinis 25 grams, Flos Chrysanthemi 25 grams, 25 grams, Radix Glycyrrhizae.Medicinal 2200 ml waters in above-mentioned are put and soaks 45 minutes in a reservoir, put on slow fire and decoct 45 minutes, take out medicinal liquid; Put into 1000 ml waters in a reservoir again, put on slow fire and decoct 30 minutes, take out medicinal liquid.By twice fried medicinal liquid mixing, mix homogeneously, by every agent 30 milliliters, each 1 dose, respectively takes 1 time sooner or later.

Each Chinese medicine combined effect in this Chinese medicine preparation, the property of medicine cooperates mutually, can play the effect of yin nourishing of enriching blood, invigorating the spleen and benefiting QI, tranquilizing by nourishing the heart, promoting QI circulation for relieving depression, tonifying kidney for preventing miscarriage.Have drug effect definite, short treating period, instant effect, has no side effect to fetus, does not affect the advantages such as normal fetal growth promoter.

clinical data

1, data and method

1.1, physical data

Get that Linyi City mental health center accepts for medical treatment trimester of pregnancy depression case 100 example, be divided into treatment group and matched group at random.Treatment group 50 example, wherein early pregnancy 12 example, midtrimester of pregnancy 18 example, late pregnancy 20 example; Matched group 50 example, wherein early pregnancy 18 example, midtrimester of pregnancy 17 example, late pregnancy 15 example.Treatment group, matched group two groups of patient's parameters there was no significant differences.

2, diagnostic criteria and case selection:

2.1, doctor trained in Western medicine classification diagnosis presses International Classification of Disease 10th edition ICD-10 diagnostic criteria, contrast HAMD (HAMD) 24 total score >=20 point, and≤35 points of persons.

2.1.1, symptom standard: low based on mental state, and have following 4 at least:

(1) hebetude, without happy sense; (2) energy goes down or tired sense; (3) psychomotor activity is sluggish or intense; (4) self evaluation too low, feel guilty or have feeling of guilt; (5) association difficulty or conscious elaborative faculty decline; (6) repeatedly there is the thought of wanting to die or have suicide, autolesionism; (7) sleep disorder; (8) appetite reduction or body weight obviously reduce; (9) hyposexuality.

2.2, Syndrome Differentiation of Traditional Chinese Medicine diagnosis is with reference to strongly fragrant sick diagnostic criteria in Ministry of Public Health " Chinese medical disease Standardization of diagnosis and curative effect ".Primary symptom: spirit depressing, weak, sleep few; Secondary disease: gastral cavity abdomen is vexed swollen, sighing frequently uncomfortable in chest, poor appetite, constipation; Light red tongue or fat, white and thin fur or greasy; Stringy and rolling pulse, or thready and weak pulse without strength.Possess above primary symptom 3, secondary disease 2, then diagnosable.

3, Therapeutic Method:

Treatment group: take Chinese medicine composition of the present invention, by every agent 30 milliliters, each 1 dose, respectively takes 1 time sooner or later.One after each meal.It within 1 month, is 1 course for the treatment of.

Matched group: take escitalopram oxalate, every day 2 times, each 10mg, one after each meal 1 month is 1 course for the treatment of.

4, curative effect and safety assessment standard:

Application HAMD scale, as evaluation instrument, is evaluated for the 1st, 2,3,4 week before medication, after medication, simultaneously the inspection such as laggard promoting the circulation of blood routine, blood biochemistry, electrocardiogram, B ultrasonic before the treatment.By the situation evaluation curative effect of clinical lessons deduction rate.

Recovery from illness: deduction rate >=75%;

Effective: 74% > deduction rate >=50%;

Effective: 49% > deduction rate >=25%;

Invalid: deduction rate < 25%.

5, therapeutic outcome

Group

Case load

Recovery from illness (rate)

Effective (rate)

Effectively (rate)

Invalid (rate)

Total effective rate

Matched group

50

8（16.0%）

15（30.0%）

12（24.0%）

15（30.0%）

70.0%

Treatment group

50

12（24.0%）

25（50.0%）

10（20.0%）

3（6.0%）

94.0%

Result shows: treatment takes Chinese medicine composition of the present invention, determined curative effect, and total effective rate reaches 94.0%, is significantly better than matched group.

Model case:

Case 1:

Lanshan District, Linyi patient, gestation 3 months, cardinal symptom is depressed, anxious, ponder over more, total consider some bad things, worry the growth promoter of child, time dysphoria, nighttime sleep is poor, and dietary amount is few, and vagina is hemorrhage on a small quantity, companion's lumbago.Take traditional Chinese medicine composition for treating of the present invention, sleep obviously improvement afterwards on the 2nd, after 10 days, emotion is clearly better, and after 20 days, symptom disappears completely, next healthy boy baby of term birth.

Case 2:

Fei County, Shandong Province patient, gestation 5 months, cardinal symptom, for feeling blue, is can't be happy, and is reluctant activity, and the reaction of sensation brain is slow, absent minded, forgets things well.Feel oneself inferior, self-accusation, thinks that what is all not so good as others.Dysphoria, to feel restless.Nighttime sleep is poor, and diet is less.Take traditional Chinese medicine composition for treating of the present invention, 2 sleep afterwards, irritated emotion obviously improves, and after 10 days, emotion is clearly better, and after 20 days, symptom disappears completely, next healthy girl baby of term birth.

Case 3:

Tancheng County, Shandong Province patient, gestation 8 months, cardinal symptom is anxious, considers that thing is more, mostly is the thing that some are bad, worry the growth promoter of child, and worry the growth that child is later, One's eyebrows knit in a frown all day, and sigh in despair, has a tearful face.Nighttime sleep is poor, sometimes sits up whole night, and daytime is weak, absent minded, and reaction is slow.And with bitter taste, perspiration, pain in the lumbar region, the symptoms such as fetal movement is sometimes frequent.Take Chinese medicine composition of the present invention, 3 sleep afterwards, diet obviously improves, and after 14 days, emotion is clearly better, and after 30 days, symptom disappears completely, next healthy boy baby of term birth.

Claims (2)

1. treat a Chinese medicine composition for trimester of pregnancy depression, it is characterized in that it is made up of the Chinese crude drug of following weight portion: Rhizoma Cyperi 30-60 part, Radix Codonopsis 30-60 part, Radix Astragali 20-40 part, Rhizoma Atractylodis Macrocephalae 20-40 part, Cortex Eucommiae 20-40 part, Herba Taxilli 30-50 part, Semen Cuscutae 30-50 part, Cortex Albiziae 15-30 part, Caulis Polygoni Multiflori 15-30 part, Radix Pseudostellariae 15-30 part, Semen Ziziphi Spinosae 10-30 part, Radix Ophiopogonis 20-40 part, Huai wheat 20-40 part, Plumula Nelumbinis 20-40 part, Flos Chrysanthemi 20-40 part, Radix Glycyrrhizae 20-40 part.

2. a kind of Chinese medicine composition for the treatment of trimester of pregnancy depression according to claims 1, is characterized in that it is made up of the Chinese crude drug of following weight portion: Rhizoma Cyperi 40-60 part, Radix Codonopsis 40-60 part, Radix Astragali 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Cortex Eucommiae 25-35 part, Herba Taxilli 35-45 part, Semen Cuscutae 35-45 part, Cortex Albiziae 20-30 part, Caulis Polygoni Multiflori 20-30 part, Radix Pseudostellariae 20-30 part, Semen Ziziphi Spinosae 15-25 part, Radix Ophiopogonis 25-35 part, Huai wheat 25-35 part, Plumula Nelumbinis 25-35 part, Flos Chrysanthemi 25-35 part, Radix Glycyrrhizae 25-35 part.