CN108853293A - Treat compounding essential oil of hemorrhoid and preparation method thereof and application method - Google Patents
Treat compounding essential oil of hemorrhoid and preparation method thereof and application method Download PDFInfo
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Abstract
The present invention provides a kind of compounding essential oil for treating hemorrhoid and preparation method thereof and application methods, are related to essential oil technical field, and the compounding essential oil of the treatment hemorrhoid includes following component according to the mass fraction：1-3 parts of Rhizoma Chuanxiong essential oil, 0.4-1 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.2-0.8 parts of Rhizoma Et Radix Notopterygii essential oil, 0.2-0.8 parts of tea tree ethereal oil, 0.15-0.75 parts of Forsythia suspense essential oil, 0.1-0.6 parts and cinnamon essential oil 0.05-0.15 parts of rhizoma acori graminei essential oil, it improves existing surgical procedure complexity and postoperative complications is more, the technical problem that western medicine toxic side effect is big and action is slow, the compounding essential oil for the treatment of hemorrhoid provided by the invention anti-inflammatory can not only sterilize, self maintenance of active cell simultaneously promotes granulation growth and quickly alleviating pain, and it can be reached by the synergistic effect between each component essential oil and be complemented each other, enhance effectiveness and expands the effect of curative effect, it is significant in efficacy simultaneously, it is rapid-action, toxic side effect is small, production is simple, it is easy to use, it is green and healthy, application prospect is good.
Description
Technical field
The present invention relates to essential oil technical field, more particularly, to a kind of compounding essential oil for treating hemorrhoid and preparation method thereof and
Application method.
Background technique
Hemorrhoid refer to that the pathologic hypertrophy of anus pad, to move down the group formed with crissum veins beneath the skin clump blood stream stasis fast, and companion
There are the symptoms such as bleeding, prolapsus.Hemorrhoid are clinical common multiple anal and rectal diseases, and disease incidence is high, and custom has " ten people, nine hemorrhoid ".It is clinical
On based on the symptoms such as hematochezia, pain, prolapsus, the state of an illness easily repeatedly, can cause the patient at each age different degrees of
Physiology and psychological pain, the life and work quality that frequently can lead to hemorrhoid patients are greatly affected.
The treatment method of hemorrhoid is more at present, treatment clinically mainly with operation based on, though surgical result compared with
It is good, however since anal canal is neural and the various complexity of blood vessel, neural Hyperalgesia etc., leads to the wound pain that hemorrhoid are postoperative under tooth trace
Majority are enabled to be difficult to endure, and surgical procedure complexity and postoperative complications etc. will increase the burden of patient.Drug therapy
Based on the class Western medicine that eases pain, toxic side effect is big and works slow.
In view of this, the present invention is specifically proposed.
Summary of the invention
The first object of the present invention is to provide a kind of compounding essential oil for treating hemorrhoid, improves existing operative treatment mistake
Journey is complicated and postoperative complications are more, the technical problem that western medicine toxic side effect is big and action is slow.
The compounding essential oil for the treatment of hemorrhoid provided by the invention, including following component according to the mass fraction：Rhizoma Chuanxiong essential oil 1-3
Part, 0.4-1 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.2-0.8 parts of Rhizoma Et Radix Notopterygii essential oil, 0.2-0.8 parts of tea tree ethereal oil, 0.15-0.75 parts of Forsythia suspense essential oil, stone
0.1-0.6 parts and cinnamon essential oil 0.05-0.15 parts of calamus essential oil.
Further, the compounding essential oil of the treatment hemorrhoid includes following component according to the mass fraction：Rhizoma Chuanxiong essential oil
1.2-2.8 parts, 0.5-0.8 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.3-0.7 parts of Rhizoma Et Radix Notopterygii essential oil, 0.3-0.7 parts of tea tree ethereal oil, Forsythia suspense essential oil 0.25-
0.7 part, 0.25-0.5 parts of rhizoma acori graminei essential oil and 0.07-0.13 parts of cinnamon essential oil.
Further, the compounding essential oil of the treatment hemorrhoid includes following component according to the mass fraction：Rhizoma Chuanxiong essential oil
1.5-2.5 parts, 0.6-0.7 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.4-0.6 parts of Rhizoma Et Radix Notopterygii essential oil, 0.4-0.6 parts of tea tree ethereal oil, Forsythia suspense essential oil 0.55-
0.65 part, 0.3-0.4 parts of rhizoma acori graminei essential oil and 0.08-0.12 parts of cinnamon essential oil.
Further, the compounding essential oil of the treatment hemorrhoid further includes 1-3 parts of common fig leaf juice essential oil according to the mass fraction
With 1-3 parts of garden burnet essential oil；
Preferably, common fig leaf juice essential oil is 2 parts, and garden burnet essential oil is 2 parts.
Further, the compounding essential oil of the treatment hemorrhoid further includes 0-98 parts of base oil according to the mass fraction；
Preferably, the base oil in Sweet Almond Oil, grape seed oil, SIMMONDSIA CHINENSIS SEED OIL or wheat-germ oil at least one
Kind；
It is further preferred that the base oil is SIMMONDSIA CHINENSIS SEED OIL.
Further, the compounding essential oil of the treatment hemorrhoid further includes 0.5-2 parts of auxiliary agent according to the mass fraction；
Preferably, the auxiliary agent includes gelling agent, moisturizer or at least one of the preservatives.
Further, the gelling agent is selected from methylcellulose, hydroxypropyl methyl cellulose, sodium cellulose glycolate, gathers
At least one of vinyl alcohol, pectin or gelatin；
Preferably, the moisturizer be selected from polyethylene glycol, propylene glycol, hexylene glycol, isoprene, butanediol, sorbierite or
At least one of glycerine；
Preferably, the preservative is methyl-isothiazol beautiful jade ketone and/or Sensiva SC50.
The second object of the present invention is to provide a kind of preparation method of compounding essential oil for treating hemorrhoid, including walks as follows
Suddenly：
By Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil, Forsythia suspense essential oil, rhizoma acori graminei essential oil, cinnamon essential oil, appoint
The common fig leaf juice essential oil of choosing, optional garden burnet essential oil, optional base oil and optional auxiliary agent are uniformly mixed, and obtain treatment hemorrhoid
The compounding essential oil of sore.
The third object of the present invention is to provide a kind of application method of compounding essential oil for treating hemorrhoid, including walks as follows
Suddenly：
The compounding essential oil of the treatment hemorrhoid is applied to affected part, is massaged into absorption.
Further, before the compounding essential oil of the treatment hemorrhoid is applied to affected part, first affected part is cleaned up.
Compared with prior art, beneficial effects of the present invention are：
The compounding essential oil extracting natural plants essential oil for the treatment of hemorrhoid provided by the invention, in traditional Chinese medicine compatibility theory and essence
Under the basis that oily blending technology combines, for the first time with Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil, rhizoma acori graminei essence
Oil, Forsythia suspense essential oil and cinnamon essential oil are raw material, and allotment, which is combined into, has obvious anti-inflammatory biocidal efficacies, can active cell self repair
The essential oil for protecting and promoting the treatment hemorrhoid of granulation growth and quickly alleviating pain, has no toxic side effect simultaneously, green and healthy, action speed
Fastly；This compounding essential oil is on the basis of traditional Chinese medicine compatibility theory, the phase using the different principle of evaporation rate between essential oil in prescription
It is auxiliary to coordinate, enhance effectiveness, expand curative effect, treat the significant in efficacy of hemorrhoid, is very suitable to the public use perplexed by hemorrhoid.
The preparation method simple process of the compounding essential oil for the treatment of hemorrhoid provided by the invention, it is easy to operate, it is suitable for industry
Change mass production, production efficiency can be effectively improved.
The application method of the compounding essential oil composition for the treatment of hemorrhoid provided by the invention is time saving and energy saving using simple and convenient,
Patient can be facilitated to use at any time.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific
Condition person carries out according to conventional conditions or manufacturer's recommended conditions.
According to an aspect of the present invention, the present invention provides a kind of compounding essential oils for treating hemorrhoid, including press mass parts
The following component of number meter：1-3 parts of Rhizoma Chuanxiong essential oil, 0.4-1 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.2-0.8 parts of Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil 0.2-
0.8 part, 0.15-0.75 parts of Forsythia suspense essential oil, 0.1-0.6 parts of rhizoma acori graminei essential oil and 0.05-0.15 parts of cinnamon essential oil.
In the present invention, the typical but non-limiting mass fraction for example 1 of Rhizoma Chuanxiong essential oil, 1.2,1.5,1.8,2.0,
2.2,2.5,2.8 or 3 parts.Rhizoma Chuanxiong essential oil has the function of promoting blood circulation, wind-expelling pain-stopping and improves local blood circulation.
The typical but non-limiting mass fraction for example 0.4 of Rhizoma Atractylodis Macrocephalae essential oil, 0.45,0.5,0.55,0.6,0.65,0.7,
0.75,0.8,0.85,0.9,0.95 or 1 part.Rhizoma Atractylodis Macrocephalae essential oil has the function of strengthening the spleen and replenishing qi and eliminate dampness and have diuretic effect.
The typical but non-limiting mass fraction for example 0.2 of Rhizoma Et Radix Notopterygii essential oil, 0.25,0.3,0.35,0.4,0.45,0.5,
0.55,0.6,0.65,0.7,0.75 or 0.8 part.Rhizoma Et Radix Notopterygii essential oil has the function of wind-damp dispelling and analgesic.
The typical but non-limiting mass fraction for example 0.2 of tea tree ethereal oil, 0.25,0.3,0.35,0.4,0.45,0.5,
0.55,0.6,0.65,0.7,0.75 or 0.8 part.Tea tree ethereal oil has the function of clearing heat and detoxicating and antibacterial.
The typical but non-limiting mass fraction for example 0.15 of Forsythia suspense essential oil, 0.2,0.25,0.3,0.35,0.4,0.5,
0.55,0.6,0.65,0.7 or 0.75 part.Forsythia suspense essential oil has the function of clearing heat and detoxicating and dispersing swelling and dissipating binds.
The typical but non-limiting mass fraction for example 0.1 of rhizoma acori graminei essential oil, 0.15,0.2,0.25,0.3,0.35,
0.4,0.45,0.5,0.55 or 0.6 part.Rhizoma acori graminei essential oil has the function of dampness elimination promoting the circulation of qi, wind-dispelling benefit numbness and swelling and pain relieving.
The typical but non-limiting mass fraction for example 0.05 of cinnamon essential oil, 0.06,0.07,0.08,0.09,0.1,
0.11,0.12,0.13,0.14 or 0.15 part.Cinnamon essential oil has the function of eliminating cold to stop pain and warming meridians and promoting circulation of qi.
The compounding essential oil extracting natural plants essential oil for the treatment of hemorrhoid provided by the invention, in traditional Chinese medicine compatibility theory and essence
Under the basis that oily blending technology combines, for the first time with Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil, rhizoma acori graminei essence
Oil, Forsythia suspense essential oil and cinnamon essential oil are raw material, and allotment, which is combined into, has obvious anti-inflammatory biocidal efficacies, can active cell self repair
The essential oil for protecting and promoting the treatment hemorrhoid of granulation growth and quickly alleviating pain, has no toxic side effect simultaneously, green and healthy, action speed
Fastly；This compounding essential oil is on the basis of traditional Chinese medicine compatibility theory, the phase using the different principle of evaporation rate between essential oil in prescription
It is auxiliary to coordinate, enhance effectiveness, expand curative effect, treat the significant in efficacy of hemorrhoid, is very suitable to the public use perplexed by hemorrhoid.
In the preferred embodiment of the present invention, the compounding essential oil for treating hemorrhoid further includes nothing according to the mass fraction
1-3 parts and 1-3 parts of garden burnet essential oil of flowers and fruits leaf essential oil.
In the present invention, the typical but non-limiting mass fraction for example 1 of common fig leaf juice essential oil, 1.2,1.4,1.6,
1.8,2,2.2,2.4,2.6,2.8 or 3 parts.
Common fig leaf juice essential oil has effects that removing toxicity for detumescence and promoting qi circulation and relieving pain, is conducive to play in hemorrhoid treating good
Auxiliaring effect.
In the present invention, the typical but non-limiting mass fraction for example 1 of garden burnet essential oil, 1.2,1.4,1.6,1.8,2,
2.2,2.4,2.6,2.8 or 3 parts.
Garden burnet essential oil has cooling blood and hemostasis, clearing heat and detoxicating and healing up sore and subduing swelling and other effects, can play in the treatment of hemorrhoid good
Good booster action.
In present invention further optimization embodiment, common fig leaf juice essential oil is 2 parts, and garden burnet essential oil is 2 parts.
In the preferred embodiment of the present invention, the compounding essential oil for treating hemorrhoid further includes base according to the mass fraction
0-98 parts of plinth oil.
In the present invention, the typical but non-limiting mass fraction for example 0 of base oil, 3,5,8,10,13,15,18,
20、23、25、28、30、33、35、38、40、43、45、48、50、53、55、58、60、63、65、68、70、73、75、78、80、
83,85,88,90,93,95 or 98 parts.
In present invention further optimization embodiment, base oil be selected from Sweet Almond Oil, grape seed oil, SIMMONDSIA CHINENSIS SEED OIL or
At least one of wheat-germ oil.
Sweet Almond Oil is a kind of neutral base oil, can promote cell turnover, has and easily absorbs, and nourishing and moisturizing are eliminated
The effect of redness, dryness and inflammation.
Grape seed oil has strong permeability, and can moisten soft skin, has effects that anti-oxidant and convergence.
SIMMONDSIA CHINENSIS SEED OIL has strong permeability, can moisten moisturizing, maintaining skin.
Wheat-germ oil has the effect of boosting metabolism, skin renewal, anti-oxidant and moist moisturizing.
In still more preferably embodiment of the invention, base oil is SIMMONDSIA CHINENSIS SEED OIL.
In the preferred embodiment of the present invention, the compounding essential oil for treating hemorrhoid further includes helping according to the mass fraction
0.5-2 parts of agent.
In the present invention, the typical but non-limiting mass fraction for example 0.5 of auxiliary agent, 0.6,0.7,0.8,0.9,1,
1.1,1.2,1.3,1.4,1.5,1.6,1.7,1.8,1.9 or 2 parts.
In present invention further optimization embodiment, auxiliary agent include in gelling agent, moisturizer or preservative at least
It is a kind of.
In the preferred embodiment of the present invention, gelling agent is water-soluble high-molecular substance, including but not limited to day
Right polymer substance, modified natural polymer substance and synthetic high polymer matter.
Water-soluble high-molecular substance is fine including but not limited to methylcellulose, hydroxypropyl methyl cellulose, hydroxypropyl methyl
Tie up plain phthalic acid ester, sodium cellulose glycolate, hydroxymethyl ethylcellulose, carboxymethylethylcellulose, acetic acid neighbour benzene two
Cellulose formiate.
Modified natural polymer substance includes but is not limited to Arabic gum, mosanom, propylene glycol alginate, agar, gelatin
With xanthan gum etc..
Synthesizing macromolecule includes but is not limited to polyethylene glycol, polyvinyl alcohol, polyvinylpyrrolidone, polyethylene acetal two
Ethylamino mistake acid esters, methacrylic acid copolymer-L, methacrylic acid copolymer-LD, methacrylic acid copolymer-S and carboxyl
Polyvinyl etc..
In present invention further optimization embodiment, gelling agent be selected from methylcellulose, hydroxypropyl methyl cellulose,
At least one of sodium cellulose glycolate, polyvinyl alcohol, pectin or gelatin.
In the preferred embodiment of the present invention, moisturizer is selected from polyalcohol.
Polyalcohol includes but is not limited to polyethylene glycol, propylene glycol, hexylene glycol, isoprene, butanediol, sorbierite or the third three
Alcohol.
In the preferred embodiment of the present invention, preservative includes but is not limited to methyl-isothiazol beautiful jade ketone and/or second
Base hexyl glycerol.
In the present invention, essential oil is 99.9% original effect that ensure that plant where the essence of vegetation.The present invention mentions
The compounding essential oil of the treatment hemorrhoid of confession is prepared by a variety of essential oils compounding, and plants essential oil has following advantage：
(1) small molecule easily absorbs：The pore dia of human epidermal is 60-80um (1000 microns=1 millimeter), and essential oil
Molecule is only that its 1/1000 to compare with human body cell be 1/5000000, thus essential oil can very rapidly penetrate to the skin and
It is rapidly absorbed in blood.Compared to Chinese herbal medicine (forms such as extracting solution, powder), the permeability of essential oil is 70 times stronger than Chinese herbal medicine,
Therefore essential oil can very rapidly penetrate to the skin in deep layer and blood and be absorbed, and play purification tissue, in confrontation
The bacterium the effect of.Avoid oral drugs to lesions of liver and kidney, using Transdermal absorption, the efficacy of a drug directly permeates lesion, alleviates disease rapidly
Shape.
(2) effect is powerful：Essential oil is 99.9% original effect that ensure that plant, due to seeping where the essence of draft
Thoroughly especially fast, pharmacological property is high, therefore on a small quantity can perform to drug effect ultimate attainment, can accomplish fast onset.The efficacy of a drug is gone directly lesion,
Alleviate illness rapidly.
(3) it has no toxic side effect：Essential oil is made from natural plant extraction, pure health, and raw material is only retained in extraction process
In most effective ingredient, refuse any addition and chemical component, allow skin enjoy no pollution.
(4) health is non-stimulated：Currently, that there are toxic side effects is strong, the problems such as being also easy to produce drug resistance and medicament residue for Western medicine, face
Bed application is very limited.And plants essential oil it is green, natural, safe and efficient with it the features such as replaced as the excellent of antibiotic
Dai Pin.
According to the second aspect of the invention, the present invention provides it is a kind of treat hemorrhoid compounding essential oil preparation method,
Include the following steps：
By Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil, Forsythia suspense essential oil, rhizoma acori graminei essential oil, cinnamon essential oil, appoint
The common fig leaf juice essential oil of choosing, optional garden burnet essential oil, optional base oil and optional auxiliary agent are uniformly mixed, and obtain treatment hemorrhoid
The compounding essential oil of sore.
The preparation method simple process of the compounding essential oil for the treatment of hemorrhoid provided by the invention, it is easy to operate, it is suitable for industry
Change mass production, production efficiency can be effectively improved.
According to the third aspect of the present invention, the present invention provides it is a kind of treat hemorrhoid compounding essential oil application method,
Include the following steps：
The compounding essential oil of the treatment hemorrhoid is applied to affected part, is massaged into absorption.
In the preferred embodiment of the present invention, before the compounding essential oil of the treatment hemorrhoid is applied to affected part,
First affected part is cleaned up.
The application method of the compounding essential oil for the treatment of hemorrhoid provided by the invention is time saving and energy saving using simple and convenient, can be fast
Speed works and fundamentally solves patient suffering.
In order to further appreciate that the present invention, effect of the present invention is done further in detail with comparative example combined with specific embodiments below
Thin explanation.Each raw material of the present invention can pass through commercially available acquisition.
Embodiment 1
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
1 part of essential oil, 1 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.2 part of Rhizoma Et Radix Notopterygii essential oil, 0.8 part of tea tree ethereal oil, 0.15 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil 0.6
Part, 0.05 part of cinnamon essential oil and 96.2 parts of SIMMONDSIA CHINENSIS SEED OIL.
Embodiment 2
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
3 parts of essential oil, 0.4 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.8 part of Rhizoma Et Radix Notopterygii essential oil, 0.2 part of tea tree ethereal oil, 0.75 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil
0.1 part, 0.15 part of cinnamon essential oil and 94.6 parts of SIMMONDSIA CHINENSIS SEED OIL.
Embodiment 3
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
1.2 parts of essential oil, 0.8 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.3 part of Rhizoma Et Radix Notopterygii essential oil, 0.7 part of tea tree ethereal oil, 0.25 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil
0.5 part, 0.07 part of cinnamon essential oil and 96.18 parts of SIMMONDSIA CHINENSIS SEED OIL.
Embodiment 4
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
2.8 parts of essential oil, 0.5 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.7 part of Rhizoma Et Radix Notopterygii essential oil, 0.3 part of tea tree ethereal oil, 0.7 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil
0.25 part, 0.13 part of cinnamon essential oil and 94.62 parts of SIMMONDSIA CHINENSIS SEED OIL.
Embodiment 5
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
2 parts of essential oil, 0.65 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.5 part of Rhizoma Et Radix Notopterygii essential oil, 0.5 part of tea tree ethereal oil, 0.5 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil
0.35 part, 0.1 part of cinnamon essential oil and 95.4 parts of wheat-germ oil.
Embodiment 6
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
1 part of essential oil, 1 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.8 part of Rhizoma Et Radix Notopterygii essential oil, 0.8 part of tea tree ethereal oil, 0.7 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil 0.6
Part, 0.1 part of cinnamon essential oil and 95 parts of Sweet Almond Oil.
Embodiment 7
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
2 parts of essential oil, 0.5 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.6 part of Rhizoma Et Radix Notopterygii essential oil, 0.6 part of tea tree ethereal oil, 0.5 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil 0.5
Part, 0.15 part of cinnamon essential oil and 95 parts of grape seed oil.
Embodiment 8
A kind of compounding essential oil for treating hemorrhoid is present embodiments provided, including following component according to the mass fraction：Rhizoma Chuanxiong
3 parts of essential oil, 0.4 part of Rhizoma Atractylodis Macrocephalae essential oil, 0.4 part of Rhizoma Et Radix Notopterygii essential oil, 0.4 part of tea tree ethereal oil, 0.5 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil
0.25 part, 0.05 part of cinnamon essential oil and 95 parts of SIMMONDSIA CHINENSIS SEED OIL.
Embodiment 9
Present embodiments provide a kind of compounding essential oil for treating hemorrhoid, the present embodiment and embodiment 8 the difference is that
It further include 2 parts of common fig leaf juice essential oil according to the mass fraction.
Embodiment 10
Present embodiments provide a kind of compounding essential oil for treating hemorrhoid, the present embodiment and embodiment 8 the difference is that
It further include 2 parts of garden burnet essential oil according to the mass fraction.
Embodiment 11
Present embodiments provide a kind of compounding essential oil for treating hemorrhoid, the present embodiment and embodiment 8 the difference is that
It further include 2 parts and 2 parts of garden burnet essential oil of common fig leaf juice essential oil according to the mass fraction.
Embodiment 12
A kind of preparation method of compounding essential oil for treating hemorrhoid is present embodiments provided, the anti-acne that embodiment 1-9 is provided is multiple
Square essential oil formulation is prepared in accordance with the following steps：
By Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil, Forsythia suspense essential oil, rhizoma acori graminei essential oil, cinnamon essential oil, appoint
The common fig leaf juice essential oil of choosing, optional garden burnet essential oil, optional base oil and optional auxiliary agent are uniformly mixed, and obtain treatment hemorrhoid
The compounding essential oil of sore.
Comparative example 1
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, the present embodiment and embodiment 8 the difference is that：
5 parts of Rhizoma Chuanxiong essential oil, 0.1 part of Rhizoma Atractylodis Macrocephalae essential oil, 1 part of Rhizoma Et Radix Notopterygii essential oil, 0.1 part of tea tree ethereal oil, 0.9 part of Forsythia suspense essential oil, rhizoma acori graminei essential oil
0.05 part, 0.3 part of cinnamon essential oil and 92.55 parts of SIMMONDSIA CHINENSIS SEED OIL.
Comparative example 2
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, the present embodiment and embodiment 8 the difference is that：
0.5 part of Rhizoma Chuanxiong essential oil, 1.5 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.1 part of Rhizoma Et Radix Notopterygii essential oil, 1 part of tea tree ethereal oil, 0.15 part of Forsythia suspense essential oil, rhizoma acori graminei essence
1 part of oil, 0.02 part of cinnamon essential oil and 95.73 parts of SIMMONDSIA CHINENSIS SEED OIL.
Comparative example 3
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Rhizoma Chuanxiong essential oil is not added.
Comparative example 4
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Rhizoma Atractylodis Macrocephalae essential oil is not added.
Comparative example 5
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Rhizoma Et Radix Notopterygii essential oil is not added.
Comparative example 6
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Tea tree ethereal oil is not added.
Comparative example 7
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Forsythia suspense essential oil is not added.
Comparative example 8
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Rhizoma acori graminei essential oil is not added.
Comparative example 9
This comparative example provides a kind of compounding essential oil for treating hemorrhoid, this comparative example and embodiment 8 the difference is that,
Cinnamon essential oil is not added.
Comparative example 10
This comparative example provides a kind of acne cream, which is commercially available MAYINGLONGZHICHUANGGAO.
The treatment hemorrhoid that the preparation method and embodiment 8 of the compounding essential oil for the treatment hemorrhoid that above-mentioned comparative example 1-9 is provided provide
The preparation method of the compounding essential oil of sore is identical, and details are not described herein.
1 pharmacological evaluation of test example-inventive formulation external application Dichlorodiphenyl Acetate causes the influence experiment 1.1 of rat hemorrhoid model tested
Animal
SD rat, half male and half female, weight 200g ± 20g.
1.2 laboratory apparatus, reagent
Glacial acetic acid, physiological saline；Electronic balance, punch.
The grouping of 1.3 drugs and preparation method
Control group：Physiological saline
1-21 group：The drug for the treatment hemorrhoid that embodiment 1-11 and comparative example 1-10 is provided.
1.4 experimentation：SD rat 220, half male and half female；The filter paper that internal diameter is 6mm is made with punch, 99.0%
Acetum is put into another 220 rat perianals respectively after sufficiently impregnating, filter paper is made to be in close contact anal skin and mucous membrane,
Filter paper 1 is used every time, and every rat replaces 1 filter paper when 0.5min, 1min；2nd day observation ulcer level, according to ulcer
The difference of area simultaneously takes into account half male and half female principle and adjusts rat and be divided into 22 groups.With 1/5000 furan before the administration of modeling each group
It mutters XiLin clean wound, sterile gauze is dried；The treatment hemorrhoid that embodiment 1-11 and comparative example 1-9 is provided are respectively applied in 1-20 group
Compounding essential oil (0.5g/ml)；The MAYINGLONGZHICHUANGGAO (0.25g/ is only) that 21 groups of coating comparative examples 10 provide, control group is with absorbent cotton
Dip in same volume physiological saline soak；It is covered after administration with preservative film, immobilization with adhesive tape, the topical application of drug is removed after 1h, physiological saline cleaning is used
Portion of officina.In the 3rd, 5,7,9,11,13 day observation ulcer part healing state is administered, evaluation ulcer integrates (evaluation criteria：Have routed
Ulcer sepage 1 divides；A little ulcer sepage 2 divides；There is eschar, basic 3 points of healing；4 points of healing completely), it the results are shown in Table 1.
1.5 experimental results such as following table
The influence (x ± s, n=10) of the external application Dichlorodiphenyl Acetate of the present invention of table 1 cause rat hemorrhoid model topical ulcers
As it can be seen from table 1 ulcer integral of the compounding essential oil for the treatment hemorrhoid that 1-11 group provides at the 11st day is higher than
3.5, hence it is evident that the ulcer higher than control group integrates, and illustrates that the compounding essential oil for the treatment of hemorrhoid provided by the invention can be substantially reduced greatly
Mouse hemorrhoid area, accelerates the healing of ulcer.
By 1-11 group with 21 groups of comparison as can be seen that treatment hemorrhoid provided by the invention compound essential oil to treatment hemorrhoid
The effect of sore is slightly better than MAYINGLONGZHICHUANGGAO, and it uses the essential oil of natural green and formulation of base oil to form, secondary without any poison
Effect, it is healthier, it is safer, it is more environmentally friendly.
By 11 groups with the comparison of 8-10 group as can be seen that the essential oil that compounds for the treatment of hemorrhoid provided by the invention adds at the same time
After entering common fig leaf juice essential oil and garden burnet essential oil, the compounding essential oil curative effect for the treatment of hemorrhoid is made more by the synergistic effect of two kinds of essential oils
Significantly, it is more advantageous to the treatment to hemorrhoid.
By 1-11 group with the comparison of 12-21 group as can be seen that treatment hemorrhoid provided by the invention compound essential oil in
Under the basis that medical compatibility and essential oil allotment combine, pass through Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, the Rhizoma Et Radix Notopterygii essence of extra fine quality number
Oil, tea tree ethereal oil, Forsythia suspense essential oil, rhizoma acori graminei essential oil, cinnamon essential oil, base oil, common fig leaf juice essential oil and garden burnet essential oil it is mutual
Coordinated, curative effect is better, can more effectively reduce rat hemorrhoid area, accelerate the healing of ulcer.
Test example 2 is in body (human body) experiment-crowd investigation on probation
2.1 choose 600 hemorrhoid patients, are randomly divided into blank group, control group and 1-13 group each 40, and blank group external application is given birth to
Salt water is managed, 8- of the embodiment of the present invention is respectively adopted in the MAYINGLONGZHICHUANGGAO treatment that control group external application comparative example 10 provides, 1-13 group
The compounding essential oil treatment for the treatment hemorrhoid that 11 and comparative example 1-9 is provided, observes each group therapeutic effect, compares each group patient 1 treatment
Recurrence rate in the follow-up period of cure rate and total effective rate and 1-1.5 after journey, the results are shown in Table 2.
2.2 hemorrhoid patients meet national Chinese medicine management board publication in 1994《Disease of tcm Standardization of diagnosis and curative effect》In it is right
The diagnostic criteria of hemorrhoid.Each group patient there are no significant in terms of gender, age, the course of disease and hemorrhoid type difference,
2.3 evaluation index：
It cures：Haemorrhoids atrophy, oedema, pain completely disappear, after an action of the bowels without oozing of blood；
It improves；All haemorrhoids abjections, oedema, pain relief, hematochezia slightly subtract；
In vain：Treatment is good without improvement sign, has no to improve.
Cure rate=healing number/every group of total number of persons * 100%
Total effective rate=(curing ten to improve)/every group of total number of persons * 100%.
Recurrence rate=recurrence number/each group of people * 100%
2.4 experimental results such as following table
2 therapeutic effect of table is compared with recurrence rate
From table 2 it can be seen that the healing number and improvement number of 1-4 group are above healing number and the improvement people of control group
Number, and recurrence rate illustrates the therapeutic effect of the compounding essential oil for the treatment of hemorrhoid provided by the invention also below the recurrence rate of control group
Significantly better than MAYINGLONGZHICHUANGGAO, therapeutic effect is significant, can effectively treat hemorrhoid, mitigates the pain of hemorrhoid patients.
By 4 groups with the comparison of 1-3 group as can be seen that the essential oil that compounds for the treatment of hemorrhoid provided by the invention is added at the same time
After common fig leaf juice essential oil and garden burnet essential oil, keep the compounding essential oil curative effect for treating hemorrhoid more aobvious by the synergistic effect of two kinds of essential oils
It writes, is more advantageous to the treatment to patient's hemorrhoid.
By 1-4 group with the comparison of 5-13 group as can be seen that treatment hemorrhoid provided by the invention compound essential oil in Chinese medicine
Under medicine compatibility and the basis that combines of essential oil allotment, by the Rhizoma Chuanxiong essential oil of extra fine quality number, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil,
The mutual collaboration of tea tree ethereal oil, Forsythia suspense essential oil, rhizoma acori graminei essential oil, cinnamon essential oil, base oil, common fig leaf juice essential oil and garden burnet essential oil
Cooperation, curative effect is better, more can effectively treat the hemorrhoid that patient is suffered from, and reduces hemorrhoid and gives patient's bring pain.
Finally it should be noted that：The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Present invention has been described in detail with reference to the aforementioned embodiments for pipe, those skilled in the art should understand that：Its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. a kind of compounding essential oil for treating hemorrhoid, which is characterized in that including following component according to the mass fraction：Rhizoma Chuanxiong essential oil 1-
3 parts, 0.4-1 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.2-0.8 parts of Rhizoma Et Radix Notopterygii essential oil, 0.2-0.8 parts of tea tree ethereal oil, 0.15-0.75 parts of Forsythia suspense essential oil,
0.1-0.6 parts and cinnamon essential oil 0.05-0.15 parts of rhizoma acori graminei essential oil.
2. the compounding essential oil for the treatment of hemorrhoid according to claim 1, which is characterized in that as follows including according to the mass fraction
Component：1.2-2.8 parts of Rhizoma Chuanxiong essential oil, 0.5-0.8 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.3-0.7 parts of Rhizoma Et Radix Notopterygii essential oil, 0.3-0.7 parts of tea tree ethereal oil,
0.25-0.7 parts of Forsythia suspense essential oil, 0.25-0.5 parts of rhizoma acori graminei essential oil and 0.07-0.13 parts of cinnamon essential oil.
3. the compounding essential oil for the treatment of hemorrhoid according to claim 1, which is characterized in that as follows including according to the mass fraction
Component：1.5-2.5 parts of Rhizoma Chuanxiong essential oil, 0.6-0.7 parts of Rhizoma Atractylodis Macrocephalae essential oil, 0.4-0.6 parts of Rhizoma Et Radix Notopterygii essential oil, 0.4-0.6 parts of tea tree ethereal oil,
0.35-0.65 parts of Forsythia suspense essential oil, 0.3-0.4 parts of rhizoma acori graminei essential oil and 0.08-0.12 parts of cinnamon essential oil.
4. the compounding essential oil for the treatment of hemorrhoid according to claim 1-3, which is characterized in that further include by mass parts
1-3 parts and 1-3 parts of garden burnet essential oil of the common fig leaf juice essential oil of number meter；
Preferably, common fig leaf juice essential oil is 2 parts, and garden burnet essential oil is 2 parts.
5. the compounding essential oil for the treatment of hemorrhoid according to claim 1-3, which is characterized in that further include by mass parts
0-98 parts of base oil of number meter；
Preferably, the base oil is selected from least one of Sweet Almond Oil, grape seed oil, SIMMONDSIA CHINENSIS SEED OIL or wheat-germ oil；
It is further preferred that the base oil is SIMMONDSIA CHINENSIS SEED OIL.
6. the compounding essential oil for the treatment of hemorrhoid according to claim 1-3, which is characterized in that further include by mass parts
0.5-2 parts of auxiliary agent of number meter；
Preferably, the auxiliary agent includes gelling agent, moisturizer or at least one of the preservatives.
7. the compounding essential oil for the treatment of hemorrhoid according to claim 6, which is characterized in that the gelling agent is selected from Methyl cellulose
At least one of element, hydroxypropyl methyl cellulose, sodium cellulose glycolate, polyvinyl alcohol, pectin or gelatin；
Preferably, the moisturizer is selected from polyethylene glycol, propylene glycol, hexylene glycol, isoprene, butanediol, sorbierite or the third three
At least one of alcohol；
Preferably, the preservative is methyl-isothiazol beautiful jade ketone and/or Sensiva SC50.
8. the preparation method of the compounding essential oil for the treatment of hemorrhoid according to claim 1-7, which is characterized in that including
Following steps：
By Rhizoma Chuanxiong essential oil, Rhizoma Atractylodis Macrocephalae essential oil, Rhizoma Et Radix Notopterygii essential oil, tea tree ethereal oil, Forsythia suspense essential oil, rhizoma acori graminei essential oil, cinnamon essential oil, optional
Common fig leaf juice essential oil, optional garden burnet essential oil, optional base oil and optional auxiliary agent are uniformly mixed, and obtain treatment hemorrhoid
Compound essential oil.
9. the application method of the compounding essential oil for the treatment of hemorrhoid according to claim 1-7, which is characterized in that including
Following steps：
The compounding essential oil of the treatment hemorrhoid is applied to affected part, is massaged into absorption.
10. the application method of the compounding essential oil for the treatment of hemorrhoid according to claim 9, which is characterized in that controlled by described
Before the compounding essential oil for the treatment of hemorrhoid is applied to affected part, first affected part is cleaned up.
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| WO2009047826A2 (en) * | 2007-10-11 | 2009-04-16 | Tuttofarmaco S.R.L. | Pharmaceutical composition comprising sucralphate and mesalazine |
| CN107744543A (en) * | 2017-09-13 | 2018-03-02 | 毓柔（上海）生物科技有限公司 | A kind of hemorrhoid health care essential oil and hemorrhoid health wet towel |
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