CN108853153A - A kind of preparation method of G. lucidum spores Softgel - Google Patents

A kind of preparation method of G. lucidum spores Softgel Download PDF

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Publication number
CN108853153A
CN108853153A CN201811103914.5A CN201811103914A CN108853153A CN 108853153 A CN108853153 A CN 108853153A CN 201811103914 A CN201811103914 A CN 201811103914A CN 108853153 A CN108853153 A CN 108853153A
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China
Prior art keywords
ganoderma lucidum
lucidum spore
spore oil
lucidum
ganoderma
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Pending
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CN201811103914.5A
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Chinese (zh)
Inventor
李坚
刘胜武
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Guizhou Ling Kang Biology Technology Co Ltd
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Guizhou Ling Kang Biology Technology Co Ltd
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Priority to CN201811103914.5A priority Critical patent/CN108853153A/en
Publication of CN108853153A publication Critical patent/CN108853153A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention discloses a kind of preparation method of G. lucidum spores Softgel, the G. lucidum spores Softgel is using lucidum spore powder as main component, by broken wall, extract obtain ganoderma lucidum spore oil, by raw material through weighing, prepare glue, pelleting, sizing, drying, select ball, wash ball, exterior and interior packing, quality inspection, storage and etc. finished product is made.Raw material proportioning selected by the present invention is scientific and reasonable, is rich in ganodenic acid, and production process is simple, is suitble to promote production.

Description

A kind of preparation method of G. lucidum spores Softgel
Technical field
The present invention relates to the preparation methods of a kind of health care product of capsule preparations more particularly to Ganoderma lucidum spore fat capsule.
Background technique
Ganoderma lucidum is famous one of medicinal fungi, is considered as mesona by civil always over the past thousands of years.The effective component of ganoderma lucidum has Ganoderma lucidum polysaccharide class, triterpenes, ucleosides, sterols, alkaloids, furan derivatives, amino acid polypeptide class, mineral element, rouge Fat acid etc..Ganoderma lucidum has various pharmacological actions, and toxicity is very low.Its pharmacological action has:Antitumor, immunological regulation resists and puts Penetrate, calm, stable, heart tonifying, decompression, the edible and medical fungis such as antibechic, relieving asthma, is hypoglycemic have health-care effect to human body, have to disease pre- Anti-, inhibition or therapeutic effect fungi.
Reishi sporule is the sexual reproductive cell of ganoderma lucidum, and whole genetic activities substances with ganoderma lucidum, effective component contains Amount is higher by 75 times of ganoderma lucidum.Ganoderma lucidum spore oil is obtained by extraction from Reishi sporule, account for Reishi sporule gross mass 15%~ 34%, the compounds such as triterpenes ganoderic acid, unsaturated fatty acid and ganoderma lucidum polysaccharide rich in, thus have more extensive Physiological activity.
Summary of the invention
The present invention discloses a kind of preparation method of G. lucidum spores Softgel, and the G. lucidum spores Softgel is with ganoderma lucidum Conidia powder is main component, by broken wall, extract obtain ganoderma lucidum spore oil, by raw material through weighing, prepare glue, pelleting, sizing, It is dry, select ball, wash ball, exterior and interior packing, quality inspection, storage and etc. finished product is made.Raw material proportioning science selected by the present invention is closed Reason is rich in ganodenic acid, and production process is simple, is suitble to promote production.
The present invention is that a kind of preparation method of G. lucidum spores Softgel is realized with following technical solution, it is characterised in that it It is made of ganoderma lucidum spore oil, gelatin, glycerol, purified water.
Ganoderma lucidum spore oil is to be extracted to obtain by ganoderma spove powder.
The ganoderma lucidum spore oil, gelatin, glycerol, purified water, characterized in that according to following portions by weight:Reishi sporule 5-8 parts oily, 1-3 parts of gelatin, 0.5-1 parts of glycerol, 1-3 parts of purified water,
The ganoderma lucidum spore oil is that ganoderma spove powder is obtained through subcritical or means of supercritical extraction.
Total triterpene >=9g/100g in the multiple G. lucidum spores Softgel.
The preparation method of the G. lucidum spores Softgel, it is characterised in that weighing including raw material, by raw material through claiming Amount, prepare glue, pelleting, sizing, drying, select ball, wash ball, exterior and interior packing, quality inspection, storage and etc. the technique stream of finished product is made Journey.
Below in conjunction with specific embodiment, invention is further described in detail.
Embodiment 1
Formula:A kind of G. lucidum spores Softgel weighs lucidum spore powder 15000g, obtains 3800g ganoderma lucidum with means of supercritical extraction Spore oil will weigh raw material 3800g ganoderma lucidum spore oil, 1000g gelatin, 500g glycerol and 1000g purified water, by preparing glue Liquid, pelleting, sizing, drying, select ball, wash ball, exterior and interior packing, quality inspection, storage and etc. be made finished product process flow obtain 15000 capsules(0.4g/).
Above-mentioned G. lucidum spores Softgel, wherein content >=9% of total triterpene in the ganoderma lucidum spore oil.
Above-mentioned G. lucidum spores Softgel, wherein capsule 12.8g containing total triterpene described in every 100g.
Embodiment 2
Formula:A kind of G. lucidum spores Softgel weighs lucidum spore powder 20000g, obtains 4000g ganoderma lucidum with sub-critical extraction Spore oil, will weigh raw material 3200g ganoderma lucidum spore oil, 800g gelatin, 400g glycerol and 800g purified water, by prepare glue, Pelleting, sizing, drying, select ball, wash ball, exterior and interior packing, quality inspection, storage and etc. be made finished product process flow obtain 12000 Grain capsule(0.4g/).
Above-mentioned G. lucidum spores Softgel, wherein content >=9% of total triterpene in the ganoderma lucidum spore oil.
Above-mentioned G. lucidum spores Softgel, wherein capsule 12.6g containing total triterpene described in every 100g.
Embodiment described above is one of present invention preferably scheme, not makees limit in any form to the present invention System, on the premise of not exceeding the technical scheme recorded in the claims there are also other variations and modifications, should belong to this In the claims of invention.

Claims (6)

1. a kind of preparation method of G. lucidum spores Softgel, it is characterised in that it is by ganoderma lucidum spore oil, gelatin, glycerol, purifying Water composition.
2. the ganoderma lucidum spore oil according to claim 1, characterized in that the ganoderma lucidum spore oil is by wall-breaking lucidum spore Sub- powder, which extracts, to be obtained.
3. the ganoderma lucidum spore oil, gelatin, glycerol, purified water according to claim 1, characterized in that according to following weight parts Number:5-8 parts of ganoderma lucidum spore oil, 1-3 parts of gelatin, 0.5-1 parts of glycerol, 1-3 parts of purified water.
4. ganoderma lucidum spore oil according to claim 1 or claim 2, characterized in that the ganoderma lucidum spore oil is ganoderma spove powder It is obtained through subcritical or means of supercritical extraction.
5. the G. lucidum spores Softgel according to claim 1, which is characterized in that the multiple G. lucidum spores Softgel Middle total triterpene >=9g/100g.
6. the preparation method of the G. lucidum spores Softgel according to claim 1, it is characterised in that the title including raw material Weight, by raw material through weighing, prepare glue, pelleting, sizing, drying, select ball, wash ball, exterior and interior packing, quality inspection, storage and etc. system At the process flow of finished product.
CN201811103914.5A 2018-09-21 2018-09-21 A kind of preparation method of G. lucidum spores Softgel Pending CN108853153A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811103914.5A CN108853153A (en) 2018-09-21 2018-09-21 A kind of preparation method of G. lucidum spores Softgel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811103914.5A CN108853153A (en) 2018-09-21 2018-09-21 A kind of preparation method of G. lucidum spores Softgel

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CN108853153A true CN108853153A (en) 2018-11-23

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282171A (en) * 2022-08-13 2022-11-04 青海净草生物科技有限公司 Ganoderma lucidum spore oil with immunity improving function and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104083409A (en) * 2014-06-17 2014-10-08 湖北绿特欣生物科技股份有限公司 Preparation method of Mythic Fungus spore oil and its softgel
CN104845732A (en) * 2015-05-06 2015-08-19 福建荣安天然植物开发有限公司 Method for efficiently extracting ganoderma lucidum spores oil by using subcritical mixed solvent
CN105837700A (en) * 2016-04-12 2016-08-10 江苏江大源生态生物科技股份有限公司 A comprehensive extraction, utilization and production method for glossy ganoderma sporocarps and spores
CN105832778A (en) * 2016-04-28 2016-08-10 上海春芝堂生物制品有限公司 Ganoderma lucidum spore oil composite preparation and preparing method thereof
CN106490603A (en) * 2016-11-08 2017-03-15 赵伟 G. lucidum spores Softgel and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104083409A (en) * 2014-06-17 2014-10-08 湖北绿特欣生物科技股份有限公司 Preparation method of Mythic Fungus spore oil and its softgel
CN104845732A (en) * 2015-05-06 2015-08-19 福建荣安天然植物开发有限公司 Method for efficiently extracting ganoderma lucidum spores oil by using subcritical mixed solvent
CN105837700A (en) * 2016-04-12 2016-08-10 江苏江大源生态生物科技股份有限公司 A comprehensive extraction, utilization and production method for glossy ganoderma sporocarps and spores
CN105832778A (en) * 2016-04-28 2016-08-10 上海春芝堂生物制品有限公司 Ganoderma lucidum spore oil composite preparation and preparing method thereof
CN106490603A (en) * 2016-11-08 2017-03-15 赵伟 G. lucidum spores Softgel and preparation method thereof

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Title
杨倩等: "亚临界萃取法提取灵芝孢子油的工艺研究", 《首届中国亚临界生物萃取技术发展论坛论文集》 *
杨珺: "灵芝孢子油软胶囊质量保证研究", 《中国优秀硕士学位论文全文数据库 工程科技I辑》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282171A (en) * 2022-08-13 2022-11-04 青海净草生物科技有限公司 Ganoderma lucidum spore oil with immunity improving function and preparation method thereof

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