CN108815584A - One kind is for curing medical epoxy resin of U.S. complex function and preparation method thereof - Google Patents

One kind is for curing medical epoxy resin of U.S. complex function and preparation method thereof Download PDF

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Publication number
CN108815584A
CN108815584A CN201810854976.3A CN201810854976A CN108815584A CN 108815584 A CN108815584 A CN 108815584A CN 201810854976 A CN201810854976 A CN 201810854976A CN 108815584 A CN108815584 A CN 108815584A
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curing
complex function
epoxy resin
liquid
medical
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CN108815584B (en
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黄文�
张莉佳
林国华
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Chang'e Innovation (wuhan) Biotechnology Co Ltd
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Chang'e Innovation (wuhan) Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/048Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0002Head or parts thereof
    • A61F2007/0003Face
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0002Head or parts thereof
    • A61F2007/0004Eyes or part of the face surrounding the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0203Cataplasms, poultices or compresses, characterised by their contents; Bags therefor
    • A61F2007/0215Cataplasms, poultices or compresses, characterised by their contents; Bags therefor containing liquids other than water
    • A61F2007/0219Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/232Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs

Abstract

The invention discloses one kind for curing U.S. complex function Medical cold gel process for preparing, the ingredient including following mass percents:0.3-6% carragheen, 0.1-5% polyvinyl alcohol, 0.5-5% asparagus polysaccharide, 1-10% glycerol, 0.1-4% lotus polyphenol.Preparation method is:A liquid is made in 0.5-5% asparagus polysaccharide heating stirring 10-20min in 40-100 DEG C of water, B liquid is made in heating stirring 10-20min in 40-100 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5%, A liquid is uniformly mixed with B liquid, 1-10% glycerol and 0.1-4% lotus polyphenol is added, it pours into after keeping 2-4h at 80-100 DEG C equipped in the film of Face film towel or eye mask towel tool, being cooled into gel can be packaged, sterilize, and be stored at shady and cool drying.Present invention is mainly used for the fast coolings of redness inflammation skin caused by medical shaping and beauty septum reset or eye and the laser at other positions, micro-shaping, photon delicate skin and crystallite grinding etc., anti-inflammatory, antibacterial and reparation, while having the effects that moisturizing, compact and anti-ageing.

Description

One kind is for curing medical epoxy resin of U.S. complex function and preparation method thereof
Technical field
The present invention relates to medical and beauty treatment skin care applications, particularly relate to a kind of medical for curing U.S. complex function Epoxy resin and preparation method thereof.
Background technique
The cost of material is low for medical aquogel, simple process, gelling properties are easily controllable, can mention to wound in terms of skin nursing For moisture, wound healing can be effectively facilitated, can also prevent adhesion, avoid secondary insult.Medical aquogel has synthesis high score at present Sub- material and natural macromolecular material, such as the patent of Patent No. CN105694319.A《A kind of medical polyethylene alcogel and its Preparation method》, the patent of Patent No. CN105351045.A《A kind of bio-medical hydrogel and its system containing fucoidin It is standby》, the patent of Patent No. CN104804199A《A kind of bio-medical composite hydrogel and preparation method and application》With it is special Benefit number is the patent of CN105327386.A《Functional aquagel medical dressing》.Wherein natural macromolecular material is based on polysaccharide, There is good biocompatibility, and there are immunological regulation, antitumor, the bioactivity such as anti-oxidant and anti-radiation.Asparagus polysaccharide It is the linear polymer being made of β-D galactolipin and 3, the fine jade disaccharides that 6- inner ether-α-L- galactolipin alternately connects, there is immune adjust Section, antitumor, anti-oxidant, antiviral, antibacterial and the physiological activity such as anti-inflammatory.Lotus polyphenol have anti-oxidant, pore refining, it is antibacterial, Anti-aging, uvioresistant brighten and the effects of moisturizing.
Medical aquogel material is chiefly to facilitate quick healing at present, and anti-inflammatory analgetic and preventing from scar etc. are clear for skin Clean, whitening, compact and anti-ageing etc. research are less.Present invention is mainly used for medical shaping and beauty septum reset or eyes and other It is the fast cooling of redness inflammation skin caused by the laser at position, micro-shaping, photon delicate skin and crystallite grinding etc., anti-inflammatory, antibacterial And reparation, while having the effects that moisturizing, compact and anti-ageing.
Summary of the invention
To solve the problems mentioned above in the background art, the purpose of the present invention is to provide one kind for curing the compound function of U.S. Can Medical cold gel process for preparing, develop for medical shaping and beauty septum reset or eye and the laser at other positions, micro- whole The fast cooling of redness inflammation skin caused by shape, photon delicate skin and crystallite grinding etc., anti-inflammatory, antibacterial and reparation, have simultaneously Moisturizing, it is compact and anti-ageing the effects of.
To achieve the above object, the technical scheme adopted by the invention is as follows:
The present invention provides one kind for curing the medical epoxy resin of U.S. complex function, the ingredient including following mass percents: 0.3-6% carragheen, 0.1-5% polyvinyl alcohol, 0.5-5% asparagus polysaccharide, 1-10% glycerol and 0.1-4% lotus polyphenol.
Further, a kind of for curing the medical epoxy resin of U.S. complex function, the ingredient including following mass percents:1% Carragheen, 0.5% polyvinyl alcohol, 1.5% asparagus polysaccharide, 6% glycerol, 2% lotus polyphenol.
Further, the polyvinyl alcohol is pharmaceutical grade Polyethylene alcohol.
The present invention also provides one kind for curing U.S. complex function Medical cold gel process for preparing, includes the following steps:
1) A liquid is configured:0.5-5% asparagus polysaccharide heating stirring 10-20min in 40-100 DEG C of water;
2) B liquid is configured:Heating stirring 10- in 40-100 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5% 20min;
3) prepared by epoxy resin:After evenly mixing by B liquid obtained by A liquid obtained by step 1) and step 2), 1-10% glycerol is added With 0.1-4% lotus polyphenol, pours into after 2-4h is kept at 80-100 DEG C equipped in the film of Face film towel or eye mask towel tool, be cooled into Gel can be packaged, sterilize, and be stored at shady and cool drying to get epoxy resin.
Further, in step 3) epoxy resin with a thickness of 0.1-0.5cm.
Further, viscosity is 500-3000mpa.s when asparagus polysaccharide concentration is 1% in step 1).
Further, sterilization method is industrial irradiation sterilizing in step 3).
In the present invention, carragheen is a kind of red algae extract, is hydrophilic natural polysaccharide.The hydrogel chemistry of polyvinyl alcohol Performance is stablized, and has viscoelasticity, and good biocompatibility is widely used in biologic medical field, such as wound dressing, oral drugs and soft Bone tissue engineer.Asparagus polysaccharide has immunological regulation, antitumor, anti-oxidant, antiviral, antibacterial and the physiological activity such as anti-inflammatory. Lotus polyphenol has the effects that anti-oxidant, pore refining, antibacterial, anti-aging, uvioresistant, brightens and moisturizing.
The addition of carragheen can significantly improve the bioactivity of polyvinyl alcohol hydrogel, effective integration asparagus polysaccharide and The effective component of lotus polyphenol so that epoxy resin has anti-inflammatory, antibacterial and repair, while having the effects that moisturizing, compact and anti-ageing.
Compared with prior art, the beneficial effects of the invention are as follows:
One kind that the present invention makes for cure the medical epoxy resin of U.S. complex function can be used for medical shaping and beauty septum reset or The fast cooling of redness inflammation skin caused by eye and the laser at other positions, micro-shaping, photon delicate skin and crystallite grinding etc., It is anti-inflammatory, antibacterial and repair, while having the effects that moisturizing, compact and anti-ageing.
Specific embodiment
To be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, below with reference to Specific embodiment, how the present invention is further explained implements.
In the present invention, carragheen, polyvinyl alcohol, asparagus polysaccharide, glycerol and lotus polyphenol are purchased from market.
The present invention provides one kind for curing the medical epoxy resin of U.S. complex function, the ingredient including following mass percents: 0.3-6% carragheen, 0.1-5% polyvinyl alcohol, 0.5-5% asparagus polysaccharide, 1-10% glycerol and 0.1-4% lotus polyphenol.
Wherein, the polyvinyl alcohol is pharmaceutical grade Polyethylene alcohol.
The present invention also provides one kind for curing U.S. complex function Medical cold gel process for preparing, includes the following steps:
1) A liquid is configured:0.5-5% asparagus polysaccharide heating stirring 10-20min in 40-100 DEG C of water;
2) B liquid is configured:Heating stirring 10- in 40-100 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5% 20min;
3) prepared by epoxy resin:After evenly mixing by B liquid obtained by A liquid obtained by step 1) and step 2), 1-10% glycerol is added With 0.1-4% lotus polyphenol, pours into after 2-4h is kept at 80-100 DEG C equipped in the film of Face film towel or eye mask towel tool, be cooled into Gel can be packaged, sterilize, and be stored at shady and cool drying to get epoxy resin.
Wherein, in step 3) epoxy resin with a thickness of 0.1-0.5cm;Viscosity when asparagus polysaccharide concentration is 1% in step 1) For 500-3000mpa.s;Sterilization method is industrial irradiation sterilizing in step 3).
Embodiment 1
One kind includes following ingredient for curing the medical epoxy resin of U.S. complex function by mass percentage:0.3-0.8% card Draw glue, 0.1-0.4% polyvinyl alcohol, 0.5-1.0% asparagus polysaccharide, 1-5% glycerol and 0.1-1.5% lotus polyphenol.
One kind is for curing U.S. complex function Medical cold gel process for preparing, and steps are as follows:
A liquid:0.5-5% asparagus polysaccharide heating stirring 10-12min in 40-50 DEG C of water.
B liquid:Heating stirring 10-12min in 40-50 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5%.
A liquid is uniformly mixed with B liquid, and 1-10% glycerol and 0.1-4% lotus polyphenol is added, after keeping 2-4h at 80-100 DEG C It pours into the film tool equipped with Face film towel or eye mask towel, being cooled into gel can be packaged, sterilize, and be stored in dry in cool place Place.
Embodiment 2
One kind includes following ingredient for curing the medical epoxy resin of U.S. complex function by mass percentage:1% carragheen, 0.5% polyvinyl alcohol, 1.5% asparagus polysaccharide, 6% glycerol, 2% lotus polyphenol.
One kind is for curing U.S. complex function Medical cold gel process for preparing, and steps are as follows:
A liquid:0.5-5% asparagus polysaccharide heating stirring 14-16min in 60-80 DEG C of water.
B liquid:Heating stirring 14-16min in 60-80 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5%.
A liquid is uniformly mixed with B liquid, and 1-10% glycerol and 0.1-4% lotus polyphenol is added, after keeping 2-4h at 80-100 DEG C It pours into the film tool equipped with Face film towel or eye mask towel, being cooled into gel can be packaged, sterilize, and be stored in dry in cool place Place.
Embodiment 3
One kind includes following ingredient for curing the medical epoxy resin of U.S. complex function by mass percentage:2-6% OK a karaoke club Glue, 1-5% polyvinyl alcohol, 2-5% asparagus polysaccharide, 7-10% glycerol and 3-4% lotus polyphenol.
One kind is for curing U.S. complex function Medical cold gel process for preparing, and steps are as follows:
A liquid:0.5-5% asparagus polysaccharide heating stirring 18-20min in 90-100 DEG C of water.
B liquid:Heating stirring 18-20min in 90-100 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5%.
A liquid is uniformly mixed with B liquid, and 1-10% glycerol and 0.1-4% lotus polyphenol is added, after keeping 2-4h at 80-100 DEG C It pours into the film tool equipped with Face film towel or eye mask towel, being cooled into gel can be packaged, sterilize, and be stored in dry in cool place Place.
Test case 1
Choose medical shaping and beauty septum reset or eye and the laser at other positions, micro-shaping, photon delicate skin and crystallite mill 20 people of subject of red and swollen inflammation skin caused by cutting etc. is recorded subject and is being used 7 using the resulting epoxy resin of embodiment 2 User's evaluation in it, is shown in Table 1.
1 20 subjects of table are using the user's evaluation in 7 days
This test case essential record 4 various aspects use feelings of the subject to epoxy resin, including it is refrigerant comfortable, mildly there is town Determine effect, absorbs fastly, there is whitening effect.As shown in Table 1, the number that evaluating in 20 subjects has corresponding effect is more than half More than, and with the extension of use time, evaluation has the number of corresponding effect gradually to increase, and shows that epoxy resin of the present invention has quickly Cooling, anti-inflammatory, it is anti-ageing the effects of.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to compared with Good embodiment describes the invention in detail, those skilled in the art should understand that, it can be to skill of the invention Art scheme is modified or replaced equivalently, and without departing from the objective and range of technical solution of the present invention, should all be covered at this In the scope of the claims of invention.

Claims (7)

1. one kind is for curing the medical epoxy resin of U.S. complex function, which is characterized in that the ingredient including following mass percents:0.3- 6% carragheen, 0.1-5% polyvinyl alcohol, 0.5-5% asparagus polysaccharide, 1-10% glycerol and 0.1-4% lotus polyphenol.
2. according to claim 1 a kind of for curing the medical epoxy resin of U.S. complex function, which is characterized in that including following matter Measure the ingredient of percentage:1% carragheen, 0.5% polyvinyl alcohol, 1.5% asparagus polysaccharide, 6% glycerol, 2% lotus polyphenol.
3. according to claim 1 a kind of for curing the medical epoxy resin of U.S. complex function, which is characterized in that the polyethylene Alcohol is pharmaceutical grade Polyethylene alcohol.
4. one kind is for curing U.S. complex function Medical cold gel process for preparing, which is characterized in that include the following steps:
1) A liquid is configured:0.5-5% asparagus polysaccharide heating stirring 10-20min in 40-100 DEG C of water;
2) B liquid is configured:Heating stirring 10-20min in 40-100 DEG C of water of polyvinyl alcohol of 0.3-6% OK a karaoke club rubber powder and 0.1-5%;
3) prepared by epoxy resin:After evenly mixing by B liquid obtained by A liquid obtained by step 1) and step 2), be added 1-10% glycerol and 0.1-4% lotus polyphenol is poured into equipped in the film of Face film towel or eye mask towel tool after keeping 2-4h at 80-100 DEG C, is cooled into solidifying Glue can be packaged, sterilize, and be stored at shady and cool drying to get epoxy resin.
5. according to claim 4 a kind of for curing U.S. complex function Medical cold gel process for preparing, which is characterized in that step It is rapid 3) in epoxy resin with a thickness of 0.1-0.5cm.
6. according to claim 4 a kind of for curing U.S. complex function Medical cold gel process for preparing, which is characterized in that step It is rapid 1) in asparagus polysaccharide concentration when being 1% viscosity be 500-3000mpa.s.
7. according to claim 4 a kind of for curing U.S. complex function Medical cold gel process for preparing, which is characterized in that its It is characterized in that, sterilization method is industrial irradiation sterilizing in step 3).
CN201810854976.3A 2018-07-31 2018-07-31 Medical cold gel with medical and American composite functions and preparation method thereof Active CN108815584B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112980058A (en) * 2021-02-19 2021-06-18 南京百思福医药科技有限公司 Co-grinding method for preparing chitosan derivative and PVA (polyvinyl alcohol) blend and application thereof
CN113307988A (en) * 2021-05-24 2021-08-27 中国科学院海洋研究所 Preparation method and application of galactofucan sulfate hydrogel
US11399882B2 (en) 2020-03-27 2022-08-02 EyeCool Therapeutics, Inc. Methods of alleviating symptoms of ocular surface discomfort using medical ice slurry
CN115611992A (en) * 2022-10-21 2023-01-17 上海海洋大学 Gracilaria lemaneiformis polysaccharide and preparation method and application thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2275898C1 (en) * 2004-10-29 2006-05-10 Закрытое акционерное общество "МИРРА-М" Method for cosmetic rehabilitation of skin tissues in post-operating and other posttraumatic conditions (variants)
CN105395434A (en) * 2015-12-21 2016-03-16 宁波大学 Application of floridoside to cosmetics
CN105662917A (en) * 2016-03-30 2016-06-15 上海白衣缘生物工程有限公司 Minimally invasive beautifying post-operation gel application and preparation method thereof
CN106983691A (en) * 2017-05-18 2017-07-28 广州娇漾生物科技有限公司 A kind of anti-oxidant pore refining sleep mask of the polyphenol containing lotus and preparation method thereof
CN107375905A (en) * 2017-08-02 2017-11-24 山东恒辰生物科技有限公司 A kind of Medical cold application for repairing skin and preparation method thereof
CN108125817A (en) * 2017-12-29 2018-06-08 武汉芘芘薇莎生物科技有限公司 A kind of postoperative reparation facial mask and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2275898C1 (en) * 2004-10-29 2006-05-10 Закрытое акционерное общество "МИРРА-М" Method for cosmetic rehabilitation of skin tissues in post-operating and other posttraumatic conditions (variants)
CN105395434A (en) * 2015-12-21 2016-03-16 宁波大学 Application of floridoside to cosmetics
CN105662917A (en) * 2016-03-30 2016-06-15 上海白衣缘生物工程有限公司 Minimally invasive beautifying post-operation gel application and preparation method thereof
CN106983691A (en) * 2017-05-18 2017-07-28 广州娇漾生物科技有限公司 A kind of anti-oxidant pore refining sleep mask of the polyphenol containing lotus and preparation method thereof
CN107375905A (en) * 2017-08-02 2017-11-24 山东恒辰生物科技有限公司 A kind of Medical cold application for repairing skin and preparation method thereof
CN108125817A (en) * 2017-12-29 2018-06-08 武汉芘芘薇莎生物科技有限公司 A kind of postoperative reparation facial mask and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
任颖朗: "龙须菜多糖结构表征及拮抗光老化免疫抑制研究", 《中国优秀硕士学位论文全文数据库 工程科技I辑》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11399882B2 (en) 2020-03-27 2022-08-02 EyeCool Therapeutics, Inc. Methods of alleviating symptoms of ocular surface discomfort using medical ice slurry
US11653969B2 (en) 2020-03-27 2023-05-23 EyeCool Therapeutics, Inc. Methods of alleviating symptoms of ocular surface discomfort using medical ice slurry
CN112980058A (en) * 2021-02-19 2021-06-18 南京百思福医药科技有限公司 Co-grinding method for preparing chitosan derivative and PVA (polyvinyl alcohol) blend and application thereof
CN113307988A (en) * 2021-05-24 2021-08-27 中国科学院海洋研究所 Preparation method and application of galactofucan sulfate hydrogel
CN113307988B (en) * 2021-05-24 2022-08-02 中国科学院海洋研究所 Preparation method and application of galactofucan sulfate hydrogel
CN115611992A (en) * 2022-10-21 2023-01-17 上海海洋大学 Gracilaria lemaneiformis polysaccharide and preparation method and application thereof

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