CN108125817A - A kind of postoperative reparation facial mask and preparation method thereof - Google Patents

A kind of postoperative reparation facial mask and preparation method thereof Download PDF

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Publication number
CN108125817A
CN108125817A CN201711497846.0A CN201711497846A CN108125817A CN 108125817 A CN108125817 A CN 108125817A CN 201711497846 A CN201711497846 A CN 201711497846A CN 108125817 A CN108125817 A CN 108125817A
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facial mask
postoperative
hydrogel
polysaccharide
solidification
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Inventor
王晓军
潘启胜
陈怀新
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Wuhan Bibiweisha Biological Technology Co Ltd
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Wuhan Bibiweisha Biological Technology Co Ltd
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Priority to CN201711497846.0A priority Critical patent/CN108125817A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention discloses a kind of postoperative reparation facial mask and preparation method thereof, the postoperative component repaired facial mask and include following mass fraction:Konjak glucomannan 12~24%, water soluble chitosan 15~19%, notoginseng polysaccharide 15~23%, oat beta glucan 9~14%, algal polysaccharides 3~10%, tea polysaccharide 3~6% and hyaluronic acid 13~38%.Postoperative reparation facial mask provided by the invention, it is excellent into gelation using konjak glucomannan, the replenishing water and preserving moisture that has with reference to a variety of biological polyoses, anti-inflammation detumescence promote wound healing, repair the effects that impaired skin, so as to reach the skin problem after effectively repairing facial orthopedic, and it can be used in the case where not adding any nutrient composition, it is non-stimulated to skin, burden will not be generated, it is easy to use.

Description

A kind of postoperative reparation facial mask and preparation method thereof
Technical field
The present invention relates to technical field of skin care, more particularly to a kind of postoperative reparation facial mask and preparation method thereof.
Background technology
It repairs the form that facial mask is mostly face paper Ensure Liquid liquid after existing orthopedic to exist, main composition is battalion Active material in nutrient solution, and in order to reach the effect of more preferable, various active materials are compounded into facial mask nutrient solution, Although there is certain effect, wherein numerous active constituents is often caused to bear or even be led to postoperative sensitivity, fragile skin Minus effect is caused, generates more serious inflammation and skin injury.
Invention content
The main object of the present invention is to propose a kind of postoperative reparation facial mask and preparation method thereof, it is intended to make postoperative reparation facial mask In do not need to add any nutrient solution, so as to avoid the harmful effect brought by nutrient solution in facial mask to postoperative skin.
To achieve the above object, the present invention proposes a kind of postoperative reparation facial mask, includes the component of following mass fraction:
Konjak glucomannan 12~24%, water soluble chitosan 15~19%, notoginseng polysaccharide 15~23%, oat β-Portugal Glycan 9~14%, algal polysaccharides 3~10%, tea polysaccharide 3~6% and hyaluronic acid 13~38%.
Preferably, glucomannans content >=90% in the konjak glucomannan.
Preferably, the water soluble chitosan is included in carboxymethyl chitosan, carboxymethyl chitosan, low-molecular weight chitoglycan At least one, wherein, the molecular weight of the low-molecular weight chitoglycan is 1000~15000Da.
Preferably, the molecular weight of the hyaluronic acid is 100~800KDa.
The present invention also proposes a kind of postoperative preparation method for repairing facial mask as described above, includes the following steps:
Hyaluronic acid is dissolved in purified water, then sequentially adds water soluble chitosan, notoginseng polysaccharide, swallow while stirring Wheat beta glucan, algal polysaccharides and tea polysaccharide add konjak glucomannan after mixing, dissolve konjak glucomannan, To form hydrogel solution;
Hydrogel solution is filled into mold, and freezing processing is carried out to the mold for being filled with hydrogel solution, is obtained Freeze the hydrogel solidified;
Vacuum freeze drying is carried out to the hydrogel for the solidification that freezes, obtains postoperative reparation facial mask.
Preferably, hyaluronic acid is dissolved in purified water, then sequentially adds water soluble chitosan, Radix Notoginseng while stirring Polysaccharide, avenabeta glucosan, algal polysaccharides and tea polysaccharide add konjak glucomannan after mixing, gather konjac mannan Sugar dissolving, the step of to form hydrogel solution in:
Hyaluronic acid, water soluble chitosan, notoginseng polysaccharide, avenabeta glucosan, algal polysaccharides, tea polysaccharide and konjaku Portugal The gross mass of mannosan is purify water quality 15~52%.
Preferably, hydrogel solution is filled into mold, and the mold for being filled with hydrogel solution is carried out at freezing In the step of managing, obtaining the hydrogel of icing solidification:The temperature of the freezing processing is -35~-60 DEG C, the freezing processing 2~15h of Shi Changwei.
Preferably, in the step of carrying out vacuum freeze drying to the hydrogel for the solidification that freezes, obtaining postoperative reparation facial mask:Institute The vacuum degree for stating vacuum freeze drying is 10~30Pa, and the temperature of the vacuum freeze drying is -35~-60 DEG C, the vacuum When a length of 12~20h of freeze-drying.
Preferably, the step of vacuum freeze drying being carried out to the hydrogel for the solidification that freezes, obtaining postoperative reparation facial mask, specifically Including:
The hydrogel for the solidification that freezes is placed in 10~30Pa, -35~-60 DEG C of vacuum low-temperature environment, in 15~35 DEG C At a temperature of make the water sublimed in the hydrogel that icing solidifies after vapor, to obtain dry postoperative reparation facial mask.
Postoperative reparation facial mask provided by the invention, it is excellent into gelation using konjak glucomannan, with reference to a variety of lifes Replenishing water and preserving moisture that object polysaccharide has, anti-inflammation detumescence promote wound healing, repair the effects that impaired skin, are effectively repaiied so as to reach Skin problem after coverlay portion orthopedic, and can be used in the case where not adding any nutrient composition, it is non-stimulated to skin, Burden will not be generated, it is easy to use.
Description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, to embodiment or will show below There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention, for those of ordinary skill in the art, without creative efforts, can be with Structure according to these attached drawings obtains other attached drawings.
Fig. 1 is the flow diagram of an embodiment of the postoperative preparation method for repairing facial mask provided by the invention.
Specific embodiment
Purpose, technical scheme and advantage to make the embodiment of the present invention are clearer, below will be in the embodiment of the present invention Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase Product.
The present invention proposes a kind of postoperative reparation facial mask and preparation method thereof, wherein, in postoperative repair surface provided by the invention In one embodiment of film, the postoperative component repaired facial mask and include following mass fraction:Konjak glucomannan 12~24%, Water soluble chitosan 15~19%, notoginseng polysaccharide 15~23%, avenabeta glucosan 9~14%, algal polysaccharides 3~10%, tea Polysaccharide 3~6% and hyaluronic acid 13~38%.
Postoperative reparation facial mask provided by the invention, it is excellent into gelation using konjak glucomannan, with reference to a variety of lifes Replenishing water and preserving moisture that object polysaccharide has, anti-inflammation detumescence promote wound healing, repair the effects that impaired skin, are effectively repaiied so as to reach Skin problem after coverlay portion orthopedic;And it is done by preparing polysaccharide solution, gel casting forming, freezing processing and vacuum refrigeration Postoperative reparation facial mask prepared by dry technique only needs facial mask being put into 1~5min of immersion in purified water, makes facial mask when in use Draw certain moisture and during with elasticity, you can directly spread on face, carry out facial reparation namely provided by the invention postoperative repair Coverlay film can be used in the case where not adding any nutrient composition, non-stimulated to skin, will not generate burden, user Just.Meanwhile postoperative reparation facial mask provided by the invention is prepared using a variety of biological polyoses as raw material, fully biodegradable, It is environmentally safe.
Konjak glucomannan has good into gelation, but if the content of wherein glucomannans is too low Words can cause facial mask to be difficult to be molded since intensity is insufficient in preparation process.In the present embodiment, the konjac mannan gathers Glucomannans content >=90% in sugar.When glucomannans content >=90% in konjak glucomannan, Amorphophallus rivieri glucomannan Revealing glycan then has higher intensity, can form stable fibre structure at the time of molding.
Water-soluble chitosan is selected, the postoperative preparation process for repairing facial mask can be simplified, avoiding the need for use has Solvent and to remain chemical reagent in facial mask obtained.In addition, chitosan have good volume antibacterial and anti-inflammation functions and Film forming may advantageously facilitate the molding of facial mask.In the present embodiment, the water soluble chitosan includes carboxymethyl chitosan, carboxylic At least one of methyl chitosan, low-molecular weight chitoglycan, wherein, the molecular weight of the low-molecular weight chitoglycan for 1000~ 15000Da。
Hyaluronic acid has effects that promote wound healing, is presently found nature also with special water retention The best substance of moisture retention in boundary, is referred to as ideal natural moisturizing factor, uses it in cosmetics, can play unique guarantor Sheath skin acts on, and can keep that skin moisturizing is smooth, fine and smooth tender, high resilience, has wrinkle resistant, crease-resistant, beauty and health care and recovery The effect of skin physiology function.In the present embodiment, the molecular weight of the hyaluronic acid is 100~800KDa.
In an embodiment of the postoperative preparation method for repairing facial mask provided by the invention, the postoperative system for repairing facial mask Preparation Method includes the following steps:
Step S10, hyaluronic acid is dissolved in purified water, then sequentially adds water soluble chitosan, three while stirring Seven polysaccharide, avenabeta glucosan, algal polysaccharides and tea polysaccharide add konjak glucomannan after mixing, make konjac mannan Glycan dissolves, to form hydrogel solution;
In the postoperative preparation method for repairing facial mask provided by the invention, it is necessary first to prepare polysaccharide solution, and described more In sugar juice, hyaluronic acid, water soluble chitosan, notoginseng polysaccharide, avenabeta glucosan, algal polysaccharides, tea polysaccharide and konjaku The gross mass of glucomannans is purify water quality 15~52%.During concrete operations, following methods progress can be used:In proportion Hyaluronic acid, water soluble chitosan, notoginseng polysaccharide, avenabeta glucosan, algal polysaccharides, tea polysaccharide and Amorphophallus rivieri glucomannan are weighed respectively After revealing glycan, first hyaluronic acid is put into purified water, 2~5min of stirring makes hyaluronic acid be dissolved in purified water, Ran Houbian Stirring side sequentially add water soluble chitosan, notoginseng polysaccharide, avenabeta glucosan, algal polysaccharides and tea polysaccharide, continue stirring 5~ 10min is dissolved and is formed to konjak glucomannan to konjak glucomannan, 4~8min of stirring after mixing, is added Hydrogel solution.Wherein, all whipping process in step S10 can be hand operated mixing, can also use people in the art Agitating device carries out well known to member.
Step S20, hydrogel solution is filled into mold, and the mold for being filled with hydrogel solution is carried out at freezing Reason obtains the hydrogel solidified that freezes;
It will be molded, and water-setting peptization will be filled in the prepared hydrogel solution injection molds (KM245 types) of step S10 The mold of liquid carries out freezing processing (carrying out freezing processing to molding hydrogel facial mask parison in a mold), makes water-setting peptization Liquid forms the hydrogel for the solidification that freezes.In the present embodiment, the temperature of the freezing processing is -35~-60 DEG C, at the freezing When a length of 2~15h of reason.In addition, the process that the hydrogel solution is filled into mold can be carried out by bottle placer, the water-setting Filling amount of the sol solution in each mold is 60~62g, to be shaped to the facial mask finished product of facial size.
Step S30, vacuum freeze drying is carried out to the hydrogel for the solidification that freezes, obtains postoperative reparation facial mask.
After chilled processing makes the hydrogel solution in injection mold be shaped to the hydrogel of icing solidification, then pass through vacuum Freeze-drying removes moisture therein, and so as to form dry postoperative reparation facial mask, all preparation processes are under cryogenic It carries out, can effectively preserve the bioactivity of polysaccharide component, and simple for process, convenient for producing in enormous quantities.
In the present embodiment, the vacuum degree of the vacuum freeze drying be 10~30Pa, the temperature of the vacuum freeze drying It is -35~-60 DEG C to spend, when a length of 12~20h of the vacuum freeze drying.Facial mask is removed by the way of vacuum freeze drying In moisture so that postoperative reparation facial mask obtained is not needed to add any preservative and can be preserved for a long time.
Wherein, step S30 is specifically included:The hydrogel for the solidification that freezes is placed in 10~30Pa, -35~-60 DEG C of vacuum In low temperature environment, the water sublimed in the hydrogel of icing solidification is made at a temperature of 15~35 DEG C after vapor, to obtain drying Postoperative reparation facial mask.That is, in the vacuum environment of 10~30Pa, by the chilled hydrogel of icing solidification for handling and obtaining In putting under -35~-60 DEG C of cryogenic conditions, it is vapor to make moisture therein directly distillation, so as to remove moisture therein, distillation Temperature is controlled at 15~35 DEG C, dry molding facial mask is taken out after 12~20h, and mask product is taken off from mold, that is, obtained Obtain the postoperative reparation facial mask finished product;Then the postoperative reparation mask product can be obtained by carrying out aseptic sealed packages.
Technical scheme of the present invention is described in further detail below in conjunction with specific embodiment, it should be understood that following real It applies example to be only used to explain the present invention, be not intended to limit the present invention.
Embodiment 1
(1) polysaccharide solution is prepared
After stirring and dissolving 2min in 600g hyaluronic acids addition 10kg purified waters, 300 hydroxyl first are sequentially added while stirring Base enclosure glycan, 250g notoginseng polysaccharides, 150g avenabeta glucosans, 50g algal polysaccharides and 50g tea polysaccharides continue to stir 5min extremely After mixing, 200g konjak glucomannans (glucomannans content is 90%) are added in, stirring 4min is to forming hydrogel Solution.
(2) the postoperative molding and drying for repairing facial mask
The hydrogel solution prepared in step (1) is injected by bottle placer in KM245 molds, then mold is placed in -36 In DEG C ultra low temperature cool house after freezing processing 3h, the hydrogel for the solidification that obtains freezing;Then it is solidifying by freezing under 12Pa vacuum conditions Solid hydrogel under -36 DEG C of cryogenic conditions, making moisture therein directly distillation, sublimation temperature is controlled 15~20 for vapor DEG C, dry molding facial mask is taken out after 13h, aseptic sealed packages is carried out after demoulding, that is, obtains postoperative reparation mask product.
Embodiment 2
(1) polysaccharide solution is prepared
After stirring and dissolving 3min in 300g hyaluronic acids addition 10kg purified waters, 200g carboxylic first is sequentially added while stirring Base enclosure glycan, 200g low-molecular weight chitoglycans, 500g notoginseng polysaccharides, 300g avenabeta glucosans, 150g algal polysaccharides and 100g Tea polysaccharide continues to stir 8min to after mixing, adds in 500g konjak glucomannans (glucomannans content is 95%), 6min is to forming hydrogel solution for stirring.
(2) the postoperative molding and drying for repairing facial mask
The hydrogel solution prepared in step (1) is injected by bottle placer in KM245 molds, then mold is placed in -50 In DEG C ultra low temperature cool house after freezing processing 10h, the hydrogel for the solidification that obtains freezing;Then it under 20Pa vacuum conditions, will freeze The hydrogel of solidification makes moisture therein directly distillation for vapor under -50 DEG C of cryogenic conditions, sublimation temperature control 20~ 30 DEG C, dry molding facial mask is taken out after 15h, aseptic sealed packages is carried out after demoulding, that is, obtains postoperative reparation mask product.
Embodiment 3
(1) polysaccharide solution is prepared
After stirring and dissolving 5min in 1000g hyaluronic acids addition 10kg purified waters, 400 hydroxyl first are sequentially added while stirring Base enclosure glycan, 400g carboxymethyl chitosans, 800g notoginseng polysaccharides, 500g avenabeta glucosans, 500g algal polysaccharides and 300g tea Polysaccharide continues to stir 10min to after mixing, adds in 1200g konjak glucomannans (glucomannans content is 90%), 8min is to forming hydrogel solution for stirring.
(2) the postoperative molding and drying for repairing facial mask
The hydrogel solution prepared in step (1) is injected by bottle placer in KM245 molds, then mold is placed in -60 In DEG C ultra low temperature cool house after freezing processing 15h, the hydrogel for the solidification that obtains freezing;Then it under 30Pa vacuum conditions, will freeze The hydrogel of solidification makes moisture therein directly distillation for vapor under -60 DEG C of cryogenic conditions, sublimation temperature control 30~ 35 DEG C, dry molding facial mask is taken out after 20h, aseptic sealed packages is carried out after demoulding, that is, obtains postoperative reparation mask product.
Repairing effect for the postoperative reparation facial mask opposite portion's shaping postoperative skin for further surveying preparation of the embodiment of the present invention, 60 subjects for carrying out facial plasty art are chosen, the age is in 25~50 one full year of life, and its face is with dry tight in various degree The problems such as taut, swelling, pain, slow skin healing.Subject is divided into 3 groups, every group of 20 people, respectively using embodiment 1, implementation Example 2 and embodiment 3 prepare the postoperative reparation facial mask of gained, are used after face cleaning, daily using once, are used continuously 30 days.
3 classes of test result point:1. it is obviously improved:The dry tight, swelling of face, pain, skin healing can be effectively improved The problems such as slow;2. slight improve:The problems such as dry tight, swelling of face, pain, slow skin healing has to be subtracted to a certain degree It is weak;3. without improvement:There is no significant difference using front and rear.Test result is as shown in table 1.
The repairing effect of postoperative reparation facial mask opposite portion's shaping postoperative skin prepared by 1 embodiment of the present invention of table
Test group It is obviously improved It is slight to improve Without improvement
Embodiment 1 12 8 0
Embodiment 2 10 10 0
Embodiment 3 13 7 0
The postoperative reparation facial mask for showing to prepare through the embodiment of the present invention by the statistical result of table 1, can be effectively facial whole Drying that shape postoperative skin occurs is tight, swelling, pain, the skin healing skin problems such as slowly.
In conclusion postoperative reparation facial mask provided by the invention, has at least the following advantages:(1) konjak portuguese gansu polyose is utilized Sugar it is excellent into gelation, the replenishing water and preserving moisture having with reference to a variety of biological polyoses, anti-inflammation detumescence, promote wound healing, repair by The functions such as skin are damaged, so as to reach the skin problem after effectively repairing facial orthopedic;Any nutrient composition can not added In the case of use, it is non-stimulated to skin, burden will not be generated, it is easy to use;It is prepared, can given birth to using a variety of biological polyoses Object is degraded, environmentally safe;(2) all preparation processes carry out under cryogenic, can effectively preserve polysaccharide component Bioactivity, and it is simple for process, it is suitble to produce in enormous quantities;By the way of vacuum freeze drying, do not need to add any anti-corrosion Agent can preserve for a long time.
It these are only the preferred embodiment of the present invention, be not intended to limit the scope of the invention, for this field For technical staff, the invention may be variously modified and varied.It is all in the spirit and principles in the present invention etc, that is made is any Modification, equivalent replacement, improvement etc. should all be included within the scope of the present invention.

Claims (9)

1. a kind of postoperative reparation facial mask, which is characterized in that include the component of following mass fraction:
Konjak glucomannan 12~24%, water soluble chitosan 15~19%, notoginseng polysaccharide 15~23%, avenabeta glucosan 9~14%, algal polysaccharides 3~10%, tea polysaccharide 3~6% and hyaluronic acid 13~38%.
2. postoperative reparation facial mask as described in claim 1, which is characterized in that Portugal's sweet dew in the konjak glucomannan gathers Sugared content >=90%.
3. postoperative reparation facial mask as described in claim 1, which is characterized in that the water soluble chitosan gathers including methylol shell At least one of sugar, carboxymethyl chitosan, low-molecular weight chitoglycan, wherein, the molecular weight of the low-molecular weight chitoglycan is 1000~15000Da.
4. postoperative reparation facial mask as described in claim 1, which is characterized in that the molecular weight of the hyaluronic acid for 100~ 800KDa。
5. a kind of preparation method of postoperative reparation facial mask as described in Claims 1-4 any one, which is characterized in that including Following steps:
Hyaluronic acid is dissolved in purified water, then sequentially add while stirring water soluble chitosan, notoginseng polysaccharide, oat β- Glucan, algal polysaccharides and tea polysaccharide add konjak glucomannan after mixing, dissolve konjak glucomannan, with shape Into hydrogel solution;
Hydrogel solution is filled into mold, and freezing processing is carried out to the mold for being filled with hydrogel solution, is frozen The hydrogel of solidification;
Vacuum freeze drying is carried out to the hydrogel for the solidification that freezes, obtains postoperative reparation facial mask.
6. the postoperative preparation method for repairing facial mask as claimed in claim 5, which is characterized in that hyaluronic acid is dissolved in purifying In water, water soluble chitosan, notoginseng polysaccharide, avenabeta glucosan, algal polysaccharides and tea polysaccharide are then sequentially added while stirring, Konjak glucomannan is added after mixing, dissolves konjak glucomannan, the step of to form hydrogel solution in:
Hyaluronic acid, water soluble chitosan, notoginseng polysaccharide, avenabeta glucosan, algal polysaccharides, tea polysaccharide and konjac mannan The gross mass of glycan is purify water quality 15~52%.
7. the postoperative preparation method for repairing facial mask as claimed in claim 5, which is characterized in that hydrogel solution is filled into mould In tool, and to be filled with hydrogel solution mold carry out freezing processing, obtain freeze solidification hydrogel the step of in:It is described The temperature of freezing processing is -35~-60 DEG C, when a length of 2~15h of the freezing processing.
8. the postoperative preparation method for repairing facial mask as claimed in claim 5, which is characterized in that the hydrogel of the solidification that freezes into Row vacuum freeze drying was obtained in postoperative the step of repairing facial mask:The vacuum degree of the vacuum freeze drying be 10~30Pa, institute The temperature for stating vacuum freeze drying is -35~-60 DEG C, when a length of 12~20h of the vacuum freeze drying.
9. the postoperative preparation method for repairing facial mask as claimed in claim 8, which is characterized in that the hydrogel of the solidification that freezes into Row vacuum freeze drying obtains postoperative the step of repairing facial mask, specifically includes:
The hydrogel for the solidification that freezes is placed in 10~30Pa, -35~-60 DEG C of vacuum low-temperature environment, in 15~35 DEG C of temperature Under make the water sublimed in the hydrogel that icing solidifies after vapor, to obtain dry postoperative reparation facial mask.
CN201711497846.0A 2017-12-29 2017-12-29 A kind of postoperative reparation facial mask and preparation method thereof Pending CN108125817A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815584A (en) * 2018-07-31 2018-11-16 嫦娥创新(武汉)生物科技有限公司 One kind is for curing medical epoxy resin of U.S. complex function and preparation method thereof
CN110478255A (en) * 2019-09-17 2019-11-22 绍兴莱洁新材料科技有限公司 A kind of preparation method of rehydration gelation dry type facial mask
CN115054559A (en) * 2022-06-27 2022-09-16 辽宁咏梅生物科技有限公司 Preparation method of skin repair solution for relieving strange marks of mask

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107115267A (en) * 2017-06-29 2017-09-01 山西大学 A kind of oligosaccharide mixture facial mask and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107115267A (en) * 2017-06-29 2017-09-01 山西大学 A kind of oligosaccharide mixture facial mask and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815584A (en) * 2018-07-31 2018-11-16 嫦娥创新(武汉)生物科技有限公司 One kind is for curing medical epoxy resin of U.S. complex function and preparation method thereof
CN110478255A (en) * 2019-09-17 2019-11-22 绍兴莱洁新材料科技有限公司 A kind of preparation method of rehydration gelation dry type facial mask
CN115054559A (en) * 2022-06-27 2022-09-16 辽宁咏梅生物科技有限公司 Preparation method of skin repair solution for relieving strange marks of mask

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