CN108789966A - 一种微流道成形工艺 - Google Patents
一种微流道成形工艺 Download PDFInfo
- Publication number
- CN108789966A CN108789966A CN201810419587.8A CN201810419587A CN108789966A CN 108789966 A CN108789966 A CN 108789966A CN 201810419587 A CN201810419587 A CN 201810419587A CN 108789966 A CN108789966 A CN 108789966A
- Authority
- CN
- China
- Prior art keywords
- fluid channel
- ink
- channel forming
- planks
- forming technology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 49
- 238000005516 engineering process Methods 0.000 title claims abstract description 12
- 239000012459 cleaning agent Substances 0.000 claims abstract description 9
- 239000003960 organic solvent Substances 0.000 claims abstract description 9
- 229940100616 topical oil Drugs 0.000 claims abstract description 6
- 239000004793 Polystyrene Substances 0.000 claims description 27
- 239000000463 material Substances 0.000 claims description 8
- 229920002223 polystyrene Polymers 0.000 claims description 6
- 238000007639 printing Methods 0.000 claims description 6
- 239000003599 detergent Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 7
- 238000005406 washing Methods 0.000 abstract description 6
- 238000005260 corrosion Methods 0.000 abstract description 3
- 230000007797 corrosion Effects 0.000 abstract description 3
- 238000010586 diagram Methods 0.000 description 4
- 238000000465 moulding Methods 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 238000003854 Surface Print Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- -1 electronics Substances 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- BGOFCVIGEYGEOF-UJPOAAIJSA-N helicin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC=C1C=O BGOFCVIGEYGEOF-UJPOAAIJSA-N 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
- B29C33/3842—Manufacturing moulds, e.g. shaping the mould surface by machining
- B29C33/3857—Manufacturing moulds, e.g. shaping the mould surface by machining by making impressions of one or more parts of models, e.g. shaped articles and including possible subsequent assembly of the parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
- B29C33/3835—Designing moulds, e.g. using CAD-CAM
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
- B29C33/40—Plastics, e.g. foam or rubber
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/26—Moulds
- B29C45/27—Sprue channels ; Runner channels or runner nozzles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
- B29C33/3842—Manufacturing moulds, e.g. shaping the mould surface by machining
- B29C33/3857—Manufacturing moulds, e.g. shaping the mould surface by machining by making impressions of one or more parts of models, e.g. shaped articles and including possible subsequent assembly of the parts
- B29C2033/3864—Spraying at least one layer to create the mould
Abstract
本发明公开了一种微流道成形工艺,在PS板块表面勾画微流道的轮廓,除了微流道以外的表面用油墨印刷,使得油墨覆盖微流道以外的表面,所述PS板块用有机溶剂进行腐蚀,使得腐蚀的地方慢慢凹陷,最终成为流道,有油墨印刷的地方用清洗剂给清洗掉,最终微流道芯片成形。该工艺有效解决了微流控芯片加工困难,精度不易掌握的难题。
Description
技术领域
本发明涉及本发明涉及复杂微流道系统的技术领域,具体涉及一种微流道成形工艺。
背景技术
微流控芯片技术是把生物、化学、医学分析过程的样品制备、反应、分离、检测等基本操作单元集成到一块微米尺度的芯片上, 自动完成分析全过程。由于它在生物、化学、医学等领域的巨大潜力,已经发展成为一个生物、化学、医学、流体、电子、材料、机械等学科交叉的崭新研究领域。由于微流控芯片里的流道过于微小,其加工成形是个难题。在当前市场上,微流控芯片多为PP、PC等塑料材料或者PMMA材料,加工方式多为注塑成形方式,微流道道孔高度和深度为0.5mm作业,其流道过于微小,无论其加工还是精度掌控方面都是个难题。塑料材料都会有一定的变形量,会导致芯片中微流道变形和微流道孔径不均,影响使用结果,并且会导致微流控芯片表面变形,对之后板与板之前键合工艺产生影响。在做微流控芯片模具时,流道的孔径为0.5mm,其流道部分在模具上为凸起,加工困难,并且极易磨损。
发明内容
为了解决以上技术问题,本发明提供一种微流道成形工艺,包括以下步骤:
(1)在PS板材表面勾画微流道轮廓;
(2)在PS板材的表面用油墨印刷;
(3)有机溶剂冲刷PS板材表面;冲刷压力和流量根据所需得到微流道的宽度和深度来确定;用高压水枪垂直冲刷,高压枪的冲刷压力0.5Mpa,流量2ml/s,蚀刻出0.5mm深度的微流道;
(4)清洗剂清洗,微流道成形。
进一步的,步骤(2)中油墨覆盖除微流道以外的表面。
进一步的,步骤(1)中PS板材以聚苯乙烯为主原料,聚苯乙烯含量99.9%经挤出而成。
进一步的,步骤(4)中清洗剂为油墨清洗剂。
本发明所采用的新型微流道成形方案有效的解决了在传统的微流道成形工艺中微流板注塑成形时所产生的塑料制品易变形的问题,同时解决了在注塑工艺中产生的模具加工难,易磨损,精度掌握不准等问题。本发明的工艺采用的是腐蚀法,使用该方法可以使微流道加工成本更低,微流板注塑更易成形,生产过程更易把控,是一种更加高效便捷的新型工艺。
附图说明
图1是本发明专利的PS板材。
图2是本发明印刷上油墨的PS板材。
图3是本发明印刷上油墨的PS板材的截面图。
图4是本发明经有机溶剂腐蚀后的PS板材的截面图。
图5为本发明成型后的截面图。
图6为本发明螺旋状微流道印刷上油墨后的示意图。
图7为本发明螺旋状微流道成型后的示意图。
图8为本发明U型微流道印刷上油墨后的示意图。
图9为本发明U型微流道成型后的示意图。
图中,1.PS板材,2.油墨,3.微流道,4.有机溶剂。
具体实施方式
如图1-5所示,一种微流道成形工艺,包括以下步骤:
(1)在PS板材1表面勾画微流道3轮廓; PS板材1以聚苯乙烯为主原料,聚苯乙烯含量99.9%,经挤出而成,能自由着色,无嗅无味无毒,不至菌类生长,具有刚性,绝缘和印刷性好等优点。
(2)在PS板材1的表面用油墨2印刷,使油墨2覆盖除微流道3以外的表面。微流道形状根据需求印制,例如环形,Z字形,厚薄均匀,无漏洞,印刷时油墨不能渗到流道中。直接在板材表面印刷微流道轮廓,有效解决了传统工艺中流道加工难,不易成型,精度不好掌控和成本高的难点。
(3)有机溶剂4冲刷PS板材1表面;有机溶剂能够腐蚀PS材料,并且不亲和油墨,有效提高蚀刻质量。冲刷压力和流量根据所需得到微流道的宽度和深度来确定;用高压水枪垂直冲刷,高压枪的冲刷压力为0.5Mpa,流量为2ml/s,蚀刻出0.5mm深度的微流道。
(4)清洗剂清洗,微流道成形。所述清洗剂为油墨清洗剂。在清洗油墨的过程中利用乳化原理,形成“水包油,油包水”的乳化液,达到清洗油墨的目的。
以下通过具体实施例对本发明做进一步阐述。
实施例1
如图6-7所示,螺旋状的微流道3,在PS 板块表面印刷如图所示的螺旋状微流道的轮廓,除了螺旋状微流道轮廓以外的表面用油墨印刷,使得油墨覆盖微流道以外的表面,所述PS板块用有机溶剂进行腐蚀,所用高压枪的冲刷压力为0.5Mpa,流量为2ml/s,使得腐蚀的地方慢慢凹陷,最终成为螺旋状流道,有油墨印刷的地方用清洗剂给清洗掉,最终螺旋状微流道芯片成形。
实施例2
微流道3具有如图9所示形状。在PS 板块表面印刷如图所示的多U型微流道的轮廓。如图8,除了U型微流道轮廓以外的表面用油墨印刷,使得油墨覆盖微流道以外的表面。所述PS板块用有机溶剂进行腐蚀,高压枪的冲刷压力为0.5Mpa,流量为2ml/s,使得腐蚀的地方慢慢凹陷,最终成为多U型状流道,有油墨印刷的地方用清洗剂给清洗掉,最终多U 型微流道芯片成形。
Claims (3)
1.一种微流道成形工艺,其特征在于:包括以下步骤:
①在PS板材(1)表面勾画微流道(3)的轮廓;
②在PS板材(1)的表面用油墨(2)印刷,油墨(2)覆盖除微流道(3)以外的表面;
③有机溶剂(4)冲刷PS板材表面;冲刷压力和流量根据所需得到微流道的宽度和深度来确定;用高压水枪垂直冲刷,冲刷压力0.5Mpa,流量2ml/s,蚀刻出0.5mm深度的微流道;
④清洗剂清洗,微流道成形。
2.按照权利要求2所述的一种微流道成形工艺,其特征在于:所述步骤(1)中PS板材以聚苯乙烯为主原料,聚苯乙烯含量99.9%,经挤出而成。
3.按照权利要求2所述的一种微流道成形工艺,其特征在于:所述步骤(4)中清洗剂为油墨清洗剂。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810419587.8A CN108789966A (zh) | 2018-05-04 | 2018-05-04 | 一种微流道成形工艺 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810419587.8A CN108789966A (zh) | 2018-05-04 | 2018-05-04 | 一种微流道成形工艺 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108789966A true CN108789966A (zh) | 2018-11-13 |
Family
ID=64093679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810419587.8A Pending CN108789966A (zh) | 2018-05-04 | 2018-05-04 | 一种微流道成形工艺 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108789966A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113071256A (zh) * | 2021-03-23 | 2021-07-06 | 合阳县虹媒文化有限公司 | 一种制作仿石浮雕作品的方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101495236A (zh) * | 2006-01-19 | 2009-07-29 | 奇奥尼公司 | 微流体芯片及化验系统 |
CN102883870A (zh) * | 2010-05-03 | 2013-01-16 | 3M创新有限公司 | 制备纳米结构的方法 |
CN102909803A (zh) * | 2012-11-15 | 2013-02-06 | 余姚市富达电子有限公司 | 水壶花纹制造方法 |
CN103774147A (zh) * | 2013-12-30 | 2014-05-07 | 天津市德中技术发展有限公司 | 一种喷头组在蚀刻区做往复运动的蚀刻方法及装置 |
CN103922603A (zh) * | 2014-04-18 | 2014-07-16 | 商丘豪宇电子科技有限公司 | 触摸屏玻璃盖板成型工艺方法 |
CN104710868A (zh) * | 2013-12-14 | 2015-06-17 | 上海泉灵信息科技有限公司 | 一种抗蚀刻感光保护油墨配方 |
CN205741219U (zh) * | 2016-06-14 | 2016-11-30 | 深圳市百诣良科技发展有限公司 | 一种双向冲刷式蚀刻喷淋装置 |
-
2018
- 2018-05-04 CN CN201810419587.8A patent/CN108789966A/zh active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101495236A (zh) * | 2006-01-19 | 2009-07-29 | 奇奥尼公司 | 微流体芯片及化验系统 |
CN102883870A (zh) * | 2010-05-03 | 2013-01-16 | 3M创新有限公司 | 制备纳米结构的方法 |
CN102909803A (zh) * | 2012-11-15 | 2013-02-06 | 余姚市富达电子有限公司 | 水壶花纹制造方法 |
CN104710868A (zh) * | 2013-12-14 | 2015-06-17 | 上海泉灵信息科技有限公司 | 一种抗蚀刻感光保护油墨配方 |
CN103774147A (zh) * | 2013-12-30 | 2014-05-07 | 天津市德中技术发展有限公司 | 一种喷头组在蚀刻区做往复运动的蚀刻方法及装置 |
CN103922603A (zh) * | 2014-04-18 | 2014-07-16 | 商丘豪宇电子科技有限公司 | 触摸屏玻璃盖板成型工艺方法 |
CN205741219U (zh) * | 2016-06-14 | 2016-11-30 | 深圳市百诣良科技发展有限公司 | 一种双向冲刷式蚀刻喷淋装置 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113071256A (zh) * | 2021-03-23 | 2021-07-06 | 合阳县虹媒文化有限公司 | 一种制作仿石浮雕作品的方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11807523B2 (en) | Three-dimensional features formed in molded panel | |
CN108789966A (zh) | 一种微流道成形工艺 | |
US20120256027A1 (en) | Cell lysis apparatus and manufacturing method thereof | |
CN105154323B (zh) | 一种单分子测序芯片 | |
CN109070075A (zh) | 具有毛细腔室的微流体装置 | |
CN103286642B (zh) | 一种液体磁性磨具孔光整加工装置 | |
CN102791468A (zh) | 制造包含纳米结构的结构的方法 | |
US20230150198A1 (en) | Molded panels | |
CN207680633U (zh) | 一种用于油包水液滴生成的离心式微流控芯片 | |
US20190001335A1 (en) | Polymerase chain reaction device including ejection nozzles | |
JP2011214838A (ja) | 樹脂製マイクロ流路チップ | |
JP3984557B2 (ja) | 電気泳動デバイス | |
FI78629C (fi) | Foerfarande foer bildande av en extrusionsform. | |
Zhou et al. | Modification of a poly (methyl methacrylate) injection‐molded microchip and its use for high performance analysis of DNA | |
CN209126069U (zh) | 一种微纳米结构微流控芯片注塑成型模具 | |
US11440002B2 (en) | Microfluidic chips with one or more vias filled with sacrificial plugs | |
KR101407238B1 (ko) | 금속-플라스틱 결합체 제조 방법 | |
KR20170111886A (ko) | 마그네슘 합금과 수지의 이종소재 접합방법 | |
JPWO2010116856A1 (ja) | マイクロチップ | |
EP1285762A3 (de) | Tropfenerzeuger für Mikrotropfen, insbesondere Düsenkopf für Tintendrucker | |
DE202008012734U1 (de) | Automotive TWIN SCOOPER | |
KR101695618B1 (ko) | 화학적 에칭을 이용한 금속-플라스틱 결합체 제조 방법 | |
WO2010016303A1 (ja) | 樹脂製基板、マイクロチップ及び射出成形金型 | |
Humphreys et al. | World-to-chip interconnects for efficient loading of genomic DNA into microfluidic channels | |
CN207591892U (zh) | 一种试剂自动转移装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181113 |
|
RJ01 | Rejection of invention patent application after publication |