CN108782870A - A kind of anti-tumor healthcare tea and preparation method thereof - Google Patents
A kind of anti-tumor healthcare tea and preparation method thereof Download PDFInfo
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- CN108782870A CN108782870A CN201810788257.6A CN201810788257A CN108782870A CN 108782870 A CN108782870 A CN 108782870A CN 201810788257 A CN201810788257 A CN 201810788257A CN 108782870 A CN108782870 A CN 108782870A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/06—Treating tea before extraction; Preparations produced thereby
- A23F3/14—Tea preparations, e.g. using additives
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Abstract
The invention belongs to health product technology fields, and in particular to a kind of anti-tumor healthcare tea and preparation method thereof, the raw material group of the health protection tea becomes：Salicornia europaeal, emblic polysaccharide, Cordyceps militaris extract, Chinese weeping cypress leaf, jujube, longan, green tea.By, for main antineoplastic component, assisting the effect of Chinese weeping cypress leaf, jujube, longan with salicornia europaeal, emblic polysaccharide and Cordyceps militaris extract, obtained health protection tea have keep fit and healthy, reinforced immunological function, the remarkable results such as antitumor.
Description
Technical field
The present invention relates to a kind of health product technology fields, more particularly, to a kind of anti-tumor healthcare tea and preparation method thereof.
Background technology
Tumour is a kind of disease for seriously threatening human life and health disease feelings complexity, almost all sites of human body, tissue,
Internal organs can fall ill.Although chemotherapy is to treat the important method of tumour, current chemotherapeutics generally existing toxicity is high, uses
Amount is big, reduces the side effects such as patient's immunity.
It is also more strong to the demand of health with the increasingly raising of compatriots' living standard.But cancer discoloration is still talked to cancer,
Because it is the trend increased year by year that carninomatosis, which lures incidence still, and there is no good plan that can seek in addition to chemotherapy, operation the treatment of cancer,
And carninomatosis also has the trend shifted significantly in terms of younger.The cooking culture of people is changing at present, tea-drinking
Also become a kind of fashion culture of people.Traditional drink such as coffee, soda are gradually eliminated by people, vegetable protein drink
Material or plant health-care beverage are more and more welcomed by the people, it is desirable that being controlled come alternatives to medication by drinking multifunctional health tea
Treat the hot spot that cancer is current people's research.
Chinese patent《A kind of anti-cancer, anticancer health-protecting tea and its manufacture craft》(number of patent application：
CN201610005737.1 a kind of anti-cancer, anticancer health-protecting tea) are disclosed, the health protection tea is with strong points, dispels to adjust immune, righting
For the purpose of evil, salubrity, there is the comprehensive health product raised to tumor patient especially based on paste.But the health protection tea is with strong
Based on body is healthy and strong, to antitumous effect unobvious.
Invention content
To solve the above-mentioned problems, the present invention provides a kind of anti-tumor healthcare tea and preparation method thereof, by with salt angle
Grass, emblic polysaccharide and Cordyceps militaris extract are main antineoplastic component, assist the effect of Chinese weeping cypress leaf, jujube, longan, obtain
Health protection tea have keep fit and healthy, reinforced immunological function, the remarkable results such as antitumor.
The present invention can be achieved through the following technical solutions：
A kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：3~7 parts of salicornia europaeal, emblic polysaccharide 6~
11 parts, 5~10 parts of Cordyceps militaris extract, 4~7 parts of Chinese weeping cypress leaf, 1~5 part of jujube, 1~5 part of longan, 14~20 parts of green tea.
Preferably, a kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：4~6 parts of salicornia europaeal, emblic
8~10 parts of polysaccharide, 6~8 parts of Cordyceps militaris extract, 5~6 parts of Chinese weeping cypress leaf, 2~4 parts of jujube, 2~4 parts of longan, green tea 16~18
Part.
Preferably, a kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：5 parts of salicornia europaeal, emblic polysaccharide
9 parts, 7 parts of Cordyceps militaris extract, 5.5 parts of Chinese weeping cypress leaf, 3 parts of jujube, 3 parts of longan, 17 parts of green tea.
Preferably, the preparation method of the emblic polysaccharide is：A. emblic is taken to be enucleated, with 50~80 DEG C of hot-water soaks 10
Slurries are heated to reflux 1~5h, filtered while hot by~60min, mashing；B. original volume 20~30% is concentrated the filtrate to, with 95%
It is 70~85% that edible alcohol, which is adjusted to solution ethanol content, stands 8~15h, and filtering precipitates successively with 80% ethyl alcohol, anhydrous second
Alcohol is washed 1~3 time, and precipitation is freeze-dried to obtain emblic Thick many candies；C. it is water-soluble emblic Thick many candies to be made into 0.2~0.8mg/ml
Liquid, with citric acid adjust PH to 3.0~4.0, then at 40~50 DEG C, be added 2.0~2.5g chitosans carry out decoloration 45~
60min；D. freeze-dried to obtain emblic polysaccharide by destainer concentration, precipitation, filtering.
Preferably, the preparation method of the Cordyceps militaris extract is：It takes Cordyceps militaris to clean drying, crushes, cross 400~600
Mesh sieves, by solid-liquid ratio 1:10 are added the ethanol solution that mass fraction is 75%, under conditions of 0.02~0.1MPa, 40~60 DEG C
It carries out thermal cycle and extracts 1.5h, extracting solution concentration is dry, obtains Cordyceps militaris extract.
Preferably, a kind of preparation method of anti-tumor healthcare tea, includes the following steps：
(1) it by salicornia europaeal drying and crushing, sieves with 100 mesh sieve, is 1 by solid-liquid ratio:4~9 are added the second that mass fraction is 60%
Alcoholic solution is placed on ultrasonic cell disruptor, carries out ultrasonic extraction 1.5h, filtering, and residue is washed with 60% ethanol water,
Filtrate is concentrated under reduced pressure for filtering, merging filtrate, and it is spare to obtain salicornia europaeal extract；
(2) it will shine upon and dry after Chinese weeping cypress leaf and green tea picking, crush, sieve with 100 mesh sieve, it is spare；
(3) by jujube decladding, longan decladding peeling is respectively dried, crushes, sieve with 100 mesh sieve, spare；
(4) above-mentioned spare salicornia europaeal extract, Chinese weeping cypress leaf, green tea, longan and emblic polysaccharide and Cordyceps militaris are extracted
Object is uniformly mixed, and sterilize 30min at 120 DEG C, packs the anti-tumor healthcare tea prepared to get the present invention.
Each main functional component mechanism of action of the present invention is as follows：
Salicornia europaeal, belongs to Chenopodiaceae, and salicornia europaeal category is distributed widely in arid and varieties in saline-alkali areas.Chinese book on Chinese herbal medicine records salicornia europaeal tool
There are soothing the liver, diuresis, decompression, cures mainly hypertension and headache, also some patents think it to adjusting immune answer for Xinjiang region
It answers hypertension and tumour is effective.Isolated compound mainly has flavones, alkaloid, steroidal, terpene etc. from salicornia europaeal, this
A little compounds have antitumor, antiviral, anti-inflammatory, antibacterial, anti-oxidant and improve the bioactivity such as immune.
Emblic also known as mountain phyllanthus emblica, Phyllanthus embical fruit, Phyllanthus embical fruit etc. are the mellow fruit of Euphorbiaceae phyllanthus plant emblic
It is real.Emblic not only has abundant nutritive value, but also with a variety of biologies such as anti-inflammatory anti-oxidant, immunological regulation, antitumor
Activity.Studies have shown that the main active of emblic has a polysaccharose substance, flavone compound, ascorbic acid, SOD enzymes and
Polyphenol compound, biological function are the results of plurality of active ingredients synergistic effect.Wherein, emblic polysaccharide, which has, removes
Free radical, it is anti-oxidant and antitumor the effects that.
Cordyceps militaris not only has high nutritive value, but also has high healthcare function.Because Cordyceps militaris contains cordyceps sinensis
The various bioactivators such as acid, cordycepin, Flavonoid substances and SOD, Cordyceps sinensis polysaccharide and abundant protein and amino acid
Deng so it is giving protection against cancer, anticancer, reducing blood lipid prevents artery sclerosis, the protection heart, brain tissue, tranquilizing soporific, and resolving sputum is relievingd asthma, protected
Lung kidney-nourishing etc. has effects that auxiliary treatment.
The present invention has following advantageous effect：
Health protection tea prepared by the present invention with salicornia europaeal, emblic polysaccharide and Cordyceps militaris extract be it is main it is antitumor at
Point, assist the effect of Chinese weeping cypress leaf, jujube, longan, obtained health protection tea that can not only keep fit and healthy, reinforced immunological function, resist and swell
The health-care effects such as tumor can also effectively treat insomnia, decrease of memory, the symptoms such as poor, dizzy of sleeping.
Specific implementation mode
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment 1
A kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：3 parts of salicornia europaeal, 6 parts of emblic polysaccharide, pupa
5 parts of Cordyceps, 4 parts of Chinese weeping cypress leaf, 1 part of jujube, 1 part of longan, 14 parts of green tea.
The preparation method of the emblic polysaccharide is：A. take emblic to be enucleated, with 50~80 DEG C of hot-water soaks 10~
Slurries are heated to reflux 1~5h, filtered while hot by 60min, mashing；B. original volume 20~30% is concentrated the filtrate to, with 95% food
It is 70~85% to be adjusted to solution ethanol content with alcohol, stands 8~15h, and filtering precipitates successively with 80% ethyl alcohol, absolute ethyl alcohol
It washes 1~3 time, precipitation is freeze-dried to obtain emblic Thick many candies；C. it is water-soluble emblic Thick many candies to be made into 0.2~0.8mg/ml
Liquid, with citric acid adjust PH to 3.0~4.0, then at 40~50 DEG C, be added 2.0~2.5g chitosans carry out decoloration 45~
60min；D. freeze-dried to obtain emblic polysaccharide by destainer concentration, precipitation, filtering.
The preparation method of the Cordyceps militaris extract is：It takes Cordyceps militaris to clean drying, crushes, cross 400~600 mesh sieve, press
Solid-liquid ratio 1:10 are added the ethanol solution that mass fraction is 75%, and heat is carried out under conditions of 0.02~0.1MPa, 40~60 DEG C
Cycle extraction 1.5h, extracting solution concentration is dry, obtains Cordyceps militaris extract.
A kind of preparation method of anti-tumor healthcare tea, includes the following steps：
(1) it by salicornia europaeal drying and crushing, sieves with 100 mesh sieve, is 1 by solid-liquid ratio:4~9 are added the second that mass fraction is 60%
Alcoholic solution is placed on ultrasonic cell disruptor, carries out ultrasonic extraction 1.5h, filtering, and residue is washed with 60% ethanol water,
Filtrate is concentrated under reduced pressure for filtering, merging filtrate, and it is spare to obtain salicornia europaeal extract；
(2) it will shine upon and dry after Chinese weeping cypress leaf and green tea picking, crush, sieve with 100 mesh sieve, it is spare；
(3) by jujube decladding, longan decladding peeling is respectively dried, crushes, sieve with 100 mesh sieve, spare；
(4) above-mentioned spare salicornia europaeal extract, Chinese weeping cypress leaf, green tea, longan and emblic polysaccharide and Cordyceps militaris are extracted
Object is uniformly mixed, and sterilize 30min at 120 DEG C, packs the anti-tumor healthcare tea prepared to get the present invention.
Embodiment 2
A kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：4 parts of salicornia europaeal, 8 parts of emblic polysaccharide, pupa
6 parts of Cordyceps, 5 parts of Chinese weeping cypress leaf, 2 parts of jujube, 2 parts of longan, 16 parts of green tea.
Embodiment 3
A kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：5 parts of salicornia europaeal, 9 parts of emblic polysaccharide, pupa
7 parts of Cordyceps, 5.5 parts of Chinese weeping cypress leaf, 3 parts of jujube, 3 parts of longan, 17 parts of green tea.
Embodiment 4
A kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：6 parts of salicornia europaeal, 10 parts of emblic polysaccharide, pupa
8 parts of Cordyceps, 6 parts of Chinese weeping cypress leaf, 4 parts of jujube, 4 parts of longan, 18 parts of green tea.
Embodiment 5
A kind of anti-tumor healthcare tea, is made of the raw material of following parts by weight：7 parts of salicornia europaeal, 11 parts of emblic polysaccharide, pupa
10 parts of Cordyceps, 7 parts of Chinese weeping cypress leaf, 5 parts of jujube, 5 parts of longan, 20 parts of green tea.
Comparative example 1
Difference lies in without addition salicornia europaeal in the health protection tea of preparation with embodiment 1.
Comparative example 2
Difference lies in without addition emblic polysaccharide in the health protection tea of preparation with embodiment 1.
Comparative example 3
Difference lies in without addition Cordyceps militaris extract in the health protection tea of preparation with embodiment 1.
Efficacy validation
It recruits 80 cancer patients to test, is randomly divided into 8 groups, every group of 10 people drink 1-5 of the embodiment of the present invention respectively
The health protection tea prepared with comparative example 1-3, takes 3-5g Instant Drinks 100ml, continuously drinks three months, extract the peripheral blood of patient daily,
The CEA values (Tumor invasion) of front and back patient are drunk with ELISA method detection, as a result as shown in table 1 below：
The peripheral blood CEA values of 1 patient of table
As seen from the above table, by the comparison of embodiment 1 and comparative example 1 it is found that add salicornia europaeal in the health protection tea of preparation,
The rate of descent of the Tumor invasion of patient can be improved 24.0%；By the comparison of embodiment 1 and comparative example 2 it is found that in preparation
Emblic polysaccharide is added in health protection tea, the rate of descent of the Tumor invasion of patient can be improved 16.8%；By life or death from 1 with it is right
Ratio 3 comparison it is found that in the health protection tea of preparation add Cordyceps militaris extract, the decline of the Tumor invasion of patient can be improved
22.0%.
In summary, addition salicornia europaeal, emblic polysaccharide and Cordyceps militaris extract in health protection tea prepared by the present invention, three
Person plays synergistic function, effectively improves the decline index of cancer patient's CEA values, has efficient antitumous effect.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect range.
Claims (6)
1. a kind of anti-tumor healthcare tea, which is characterized in that be made of the raw material of following parts by weight：3~7 parts of salicornia europaeal, emblic
6~11 parts of sub- polysaccharide, 5~10 parts of Cordyceps militaris extract, 4~7 parts of Chinese weeping cypress leaf, 1~5 part of jujube, 1~5 part of longan, green tea 14~
20 parts.
2. a kind of anti-tumor healthcare tea according to claim 1, which is characterized in that by the raw material group of following parts by weight
At：4~6 parts of salicornia europaeal, 8~10 parts of emblic polysaccharide, 6~8 parts of Cordyceps militaris extract, 5~6 parts of Chinese weeping cypress leaf, 2~4 parts of jujube,
2~4 parts of longan, 16~18 parts of green tea.
3. a kind of anti-tumor healthcare tea according to claim 2, which is characterized in that by the raw material group of following parts by weight
At：5 parts of salicornia europaeal, 9 parts of emblic polysaccharide, 7 parts of Cordyceps militaris extract, 5.5 parts of Chinese weeping cypress leaf, 3 parts of jujube, 3 parts of longan, green tea 17
Part.
4. according to a kind of anti-tumor healthcare tea of claims 1 to 3 any one of them, which is characterized in that the emblic polysaccharide
Preparation method be：
A. emblic is taken to be enucleated, with 50~80 DEG C of 10~60min of hot-water soak, slurries are heated to reflux 1~5h, while hot by mashing
Filtering；
B. original volume 20~30% is concentrated the filtrate to, it is 70~85% to be adjusted to solution ethanol content with 95% edible alcohol, quiet
8~15h is set, is filtered, precipitation is washed 1~3 time with 80% ethyl alcohol, absolute ethyl alcohol successively, and precipitation is freeze-dried that emblic is slightly more
Sugar；
C. emblic Thick many candies are made into 0.2~0.8mg/ml aqueous solutions, PH to 3.0~4.0 are adjusted with citric acid, then 40
At~50 DEG C, 2.0~2.5g chitosans are added and carry out 45~60min of decoloration；
D. freeze-dried to obtain emblic polysaccharide by destainer concentration, precipitation, filtering.
5. according to a kind of anti-tumor healthcare tea of claims 1 to 3 any one of them, which is characterized in that the Cordyceps militaris extraction
The preparation method of object is：It takes Cordyceps militaris to clean drying, crushes, 400~600 mesh sieve is crossed, by solid-liquid ratio 1:10 are added mass fraction
For 75% ethanol solution, thermal cycle extraction 1.5h is carried out under conditions of 0.02~0.1MPa, 40~60 DEG C, extracting solution is dense
Contracting, it is dry, obtain Cordyceps militaris extract.
6. a kind of prepare such as a kind of method of anti-tumor healthcare tea of Claims 1 to 5 any one of them, which is characterized in that packet
Include following steps：
(1) it by salicornia europaeal drying and crushing, sieves with 100 mesh sieve, is 1 by solid-liquid ratio:The ethyl alcohol that 4~9 addition mass fractions are 60% is molten
Liquid is placed on ultrasonic cell disruptor, carries out ultrasonic extraction 1.5h, filtering, and residue is washed with 60% ethanol water, mistake
Filtrate is concentrated under reduced pressure for filter, merging filtrate, and it is spare to obtain salicornia europaeal extract；
(2) it will shine upon and dry after Chinese weeping cypress leaf and green tea picking, crush, sieve with 100 mesh sieve, it is spare；
(3) by jujube decladding, longan decladding peeling is respectively dried, crushes, sieve with 100 mesh sieve, spare；
(4) above-mentioned spare salicornia europaeal extract, Chinese weeping cypress leaf, green tea, longan and emblic polysaccharide and Cordyceps militaris extract are mixed
It closes uniformly, sterilize 30min at 120 DEG C, packs the anti-tumor healthcare tea prepared to get the present invention.
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| CN201810788257.6A CN108782870A (en) | 2018-07-17 | 2018-07-17 | A kind of anti-tumor healthcare tea and preparation method thereof |
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| CN201810788257.6A CN108782870A (en) | 2018-07-17 | 2018-07-17 | A kind of anti-tumor healthcare tea and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110200283A (en) * | 2019-07-08 | 2019-09-06 | 哈尔滨工业大学 | A kind of curcumin composite particles electuary with anti-oxidation function |
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