CN1087622C - Chinese patent medicine for treating chronic gastritis and peptic ulcer - Google Patents

Chinese patent medicine for treating chronic gastritis and peptic ulcer Download PDF

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CN1087622C
CN1087622C CN99112273A CN99112273A CN1087622C CN 1087622 C CN1087622 C CN 1087622C CN 99112273 A CN99112273 A CN 99112273A CN 99112273 A CN99112273 A CN 99112273A CN 1087622 C CN1087622 C CN 1087622C
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rhizoma
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chronic gastritis
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CN1236639A (en
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于盈光
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Abstract

The present invention discloses a Chinese patent medicine for treating chronic gastritis and peptic ulcer. The present invention is characterized in that perilla stem, nutgrass galingale rhizome, dried orange peel, magnolia bark, rhubarb, fructus aurantii immaturus, radish seed, red sage root, astragalus root, chicken's gizzard-membrane, bletilla, coptis root, evodia fruit, astragalus root, lindera strychnifolium vill, dandelion, radix sophorae flavescentis, etc. are adopted as raw materials and are prepared into the Chinese patent medicine according to certain proportion by weight. The present invention has the effects of vital energy regulation, dampness elimination, blood circulation promotion, cold dispersion and sedimentation elimination to achieve the purpose of treating chronic gastritis and peptic ulcer.

Description

The Chinese patent medicine of treatment chronic gastritis, peptic ulcer disease
The present invention relates to a kind of Chinese patent medicine, particularly treat the Chinese patent medicine of chronic gastritis, peptic ulcer disease.
Along with the extensive use of fibergastroscope, the patient who is diagnosed as chronic gastritis is more and more in recent years.According to hygiene department's statistics, hospital outpatient is accepted gastroscopy person, and 80-90% all has stomach lining inflammation in various degree; And another investigation also shows, is 11.34% at China's Peptic Ulcers sickness rate, calculates by China's existing population, and Peptic Ulcers patient has 100,000,000 people approximately, and visible chronic gastritis and Peptic Ulcers are still commonly encountered diseases and frequently-occurring disease in China.
The discovery of helicobacter pylori (HP) makes people produce important breakthrough on understanding and treatment chronic gastritis and Peptic Ulcers.International gastroenterologist points out that the essence of digestive tract ulcer disease is helicobacter pylori related disease, and chronic gastritis and helicobacter pylori also have firm corresponding relation.The recall rate of chronic gastropathy patient gastric mucose pylorospirobacillus is up to more than 80%.As long as helicobacter pylori can be disposed, most peptic ulcer disease and part chronic gastritis can be effected a radical cure.Before helicobacter pylori was found, numerous Chinese and western drugses were symptomatic treatment, often caused the state of an illness to be incured loss through delay and outbreak repeatedly.At present, remove helicobacter pylori,, make the time of application and dosage be subjected to strict restriction again because of usually causing than serious adverse though advocate the multiple antibiotic of associating.Chinese medicine decoction is loose because of regulating QI to expel dampness class medicine fragrant odour is hot, and active ingredient (volatile oil) Chang Yin decocts overlong time and a large amount of volatilization.
The objective of the invention is to regulate the flow of vital energy, damp eliminating, invigorate blood circulation, cold expelling, eliminate indigestion, assistant must rise temper with replenishing QI to invigorate the spleen, gastric qi must be fallen, irritability must be transferred, all dirty functional rehabilitations are normal, QI and bloodization is given birth to vigorous, and plays the effect of treatment chronic gastritis, peptic ulcer disease.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to chronic gastritis and peptic ulcer disease mechanism.With reference to modern pharmacological research, select for use regulating QI to expel dampness, heat clearing away QI invigorating class medicine formulated, the powerful effect of killing or suppress helicobacter pylori is arranged, tangible digestive tract power effect is arranged again, can obviously improve distension and fullness in the abdomen, pain, acid regurgitation, to reach the adjusting digestive tract power, the effect of radical cure chronic gastritis and peptic ulcer.
The present invention is formulated by pure Chinese medicine, so human body is not had any toxic action.
Prescription of the present invention and weight proportion are as follows:
Caulis Perillae 20-30 Rhizoma Cyperi 10-15 Pericarpium Citri Reticulatae 6-10 Cortex Magnoliae Officinalis 6-10 Radix Et Rhizoma Rhei 6-10
Fructus Aurantii 6-10 Semen Raphani 20-30 Radix Salviae Miltiorrhizae 10-15 Herba Pogostemonis 20-30 Endothelium Corneum Gigeriae Galli 6-10
Pseudobulbus Bletillae (Rhizoma Bletillae) 6-10 Rhizoma Coptidis 6-10 Fructus Evodiae 1-3 Radix Astragali 20-30 Radix Linderae 6-10
Herba Taraxaci 6-10 Radix Sophorae Flavescentis 3-6
Use the above-mentioned prescription treatment of the present invention chronic gastritis, peptic ulcer disease, curative effect is obvious, and antibiotic, antacid, pain relieving, adjusting gastrointestinal function are rapid, and taking convenience has no side effect, effective percentage 100%, and obvious effective rate 87%, cure rate is more than 76%.
Below in conjunction with embodiment the present invention is described in detail:
Vital energy regualting and blood circulation-promoting class medicine among the present invention:
Caulis Perillae, Rhizoma Cyperi, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Salviae Miltiorrhizae
The dyspepsia and intestinal stasis relieving class:
Radix Et Rhizoma Rhei, Semen Raphani, Endothelium Corneum Gigeriae Galli
Invigorating the spleen and benefiting QI removing dampness warming the interior class:
The Radix Astragali, Cortex Magnoliae Officinalis, Herba Pogostemonis, Fructus Evodiae, the Radix Linderae, Pseudobulbus Bletillae (Rhizoma Bletillae)
The clearing away heat-damp and promoting diuresis class:
Rhizoma Coptidis, Radix Sophorae Flavescentis, dandelion
Among the present invention first of the monarch for Caulis Perillae: performance suffering, sweet, tepor, return the taste warp, promoting the circulation of QI to alleviate the stagnation in middle-JIAO contains volatile oil, and Main Ingredients and Appearance is a perillaldehyde in the oil, can promote gastric secretion, increases gastrointestinal peristalsis.(1. see " Chinese medicine summary " 81 pages, Suzhou health school, the Yu Daxiang chief editor, in June, 1985, the People's Health Publisher publishes)
Rhizoma Cyperi: nature and flavor suffering, little hardship, return Liver Channel, the depressed liver-energy dispersing and QI regulating pain relieving contains volatile oil, and Main Ingredients and Appearance is cyperone, cyperene, cyperol etc. in the oil, can promote gastrointestinal motility.(the same 1. 120 pages)
The Radix Linderae: nature and flavor suffering, temperature, return spleen channel, the cold expelling promoting the circulation of QI to relieve pain contain volatile oil, and Main Ingredients and Appearance is lindenrane, linderane etc. in the oil, can promote enterokinesia, promote intestinal gas to discharge.(the same 1. 120 pages)
Pericarpium Citri Reticulatae: nature and flavor suffering, hardship, temperature, return spleen channel, dampness in the accent of regulating the flow of vital energy.Contain volatile oil, Main Ingredients and Appearance is d-limonen, citral, hesperetin etc. in the oil, and digestive tract is had the abirritate effect, is beneficial to the discharge of intestinal gas, and promotes gastric secretion, helps digestion.(the same 1. 119 pages)
Fructus Aurantii: nature and flavor suffering, hardship, be slightly cold, return the taste warp, promoting the circulation of QI to alleviate the stagnation in middle-JIAO removes and expands, and contains volatile oil, and Main Ingredients and Appearance is d-citral, aromatic alcohol, hesperidin etc. in the oil, can excited gastrointestinal function, and the gastrointestinal peristalsis rhythm and pace of moving things is strengthened.(the same 1. 119 pages)
Semen Raphani: nature and flavor suffering, sweet, flat, return the taste warp, the promoting digestion and removing stagnation sending down the abnormal ascending QI contains that fat is grease proofing, volatile oil, sulfur glycoside, flavonoid glycoside etc., and excited digestive tract glandular secretion effect is arranged.(the same 1. 140 pages)
Endothelium Corneum Gigeriae Galli: nature and flavor are sweet, flat, return spleen, stomach, small intestine meridian, strengthening the spleen to promote digestion.Contain gastric hormone, high protein, several amino acids can make gastric secretion and acidity increase, and the motion function of stomach strengthens, and emptying is quickened.Contained gastric hormone is heated easily destroyed, can not fry for a long time, and oral Endothelium Corneum Gigeriae Galli powder, the stomach motor function obviously strengthens.(the same 1. 140 pages)
Radix Et Rhizoma Rhei: the nature and flavor hardship, tremble with fear, return spleen, stomach, liver, large intestine channel, stasis removing, heat clearing and blood circulation promoting.Contain emodin, chrysophanic acid, chrysophanol etc., can stimulate intestinal wall, secretions is increased, increase enterokinesia.Kill helicobacter pylori activity (the same 1. 100 pages), (2. seeing " chronic gastritis and Peptic Ulcers " 140 pages, Shandong Prov. Hospital, Qin Chengyong chief editor, nineteen ninety-five, Shandong science tech publishing house)
Cortex Magnoliae Officinalis: nature and flavor hardship, suffering, temperature, return spleen, stomach, large intestine channel, the promoting the circulation of QI to remove dampness removing food stagnancy contains volatile oil, and Main Ingredients and Appearance is sagittol, Cortex Magnoliae Officinalis powder, tetrahydrochysene Cortex Magnoliae Officinalis powder etc. in the oil, and the mucosa that can stimulate digestion causes reflex irritation (the same 1. 104 pages)
Herba Pogostemonis: nature and flavor suffering, tepor, return spleen, stomach warp, the removing dampness preventing or arresting vomiting contains volatile oil, and Main Ingredients and Appearance is estragole, anisaldehyde etc. in the oil, can promote gastrointestinal secretion, strengthens eupepsy.(the same 1. 103 pages)
Fructus Evodiae: nature and flavor suffering, hardship, heat.Dispersing cold for relieving pain.Soothing the liver therapeutic method to keep the adverse QI flowing downwards dampness.Contain volatile oil, Main Ingredients and Appearance is evodene, evoxine etc. in the oil, and digestion promoting function is arranged, and can discharge the intestinal pneumatosis, prevents enteral abnormal fermentation.(the same 1. 99 pages)
The Radix Astragali: sweet, the tepor of nature and flavor, return lung, spleen channel, tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, contains saccharide, choline, folic acid etc.(the same 1. 130 pages)
Radix Salviae Miltiorrhizae: the nature and flavor hardship, be slightly cold, return liver, heart channel, the blood circulation promoting and blood stasis dispelling pain that disappears mainly contains tanshinone, and the inhibition helicobacter pylori activity is arranged.(the same 2. 140 pages)
Rhizoma Coptidis: nature and flavor hardship, cold, return liver, stomach, large intestine channel, the hot dampness detoxifcation that disappears contains a large amount of berberines and a small amount of coptisine, 13-methyl-.psi.-coptisine. etc., and the stronger helicobacter pylori activity of killing is arranged.(the same 2. 140 pages)
Radix Sophorae Flavescentis: nature and flavor hardship, cold, return liver, large intestine channel, clearing away heat-damp and expelling toxic material contains multiple alkaloid, and wherein mainly containing effective constituent is matrine, oxymatrine, and helicobacter pylori is had killing action.(the same 2. 140 pages)
Herba Taraxaci: nature and flavor hardship, Great Cold, return liver, stomach warp, detoxification and promoting urination contains taraxasterol, taraxerol, taraxacin etc., and helicobacter pylori is had killing action.(the same 2. 140 pages)
Pseudobulbus Bletillae (Rhizoma Bletillae): the nature and flavor hardship, be slightly cold, return liver stomach warp, astringing to arrest bleeding, detumescence and promoting granulation.The master contains volatile oil, phlegmatic temperament and mannan etc., and its high viscosity can form certain thickness gluey film at gastric, shields.(the same 1. 127 pages)
All medicines are synthetic, vital energy regualting and blood circulation-promoting, be good for the stomach disappear stagnant, QI invigorating removing dampness, play antiinflammatory, antacid, pain relieving, the effect of reparation gastric mucosa, thereby reach the purpose of radical cure chronic gastropathy.
Motherland's medical science has absorbed mutual generation of five phases restriction or checking relation in five elements and organic conception theory in the Chinese ancient philosophy, thinks to have confidential relation between the vital organs of the human body on physiology and pathology, and this disease of ZANG-organs often causes the disease of other internal organs, and the disease of other internal organs also can cause the pathological changes of these internal organs.Aspect the cause of disease, not only there is exopathogen to cause a disease, the daily life drinking and eating irregularly is also arranged and cause internal injury, internal injury caused by excess of seven emotions also occupies considerable status in the pathogen and pathology of tcm theory, various paathogenic factors interact, and finally cause the dysfunction of taste internal organs, disorder of QI and blood and disease takes place.
The chronic gastropathy patient, often careless because of daily life, diseases caused by exogenous pathogenic factor cold-evil, interior visitor are in stomach, and cold having the property of contraction causes disorder of stomach-QI and pain; Eating and drinking without temperance, the satiety starvation causes stomach-QI being unable to descend normally; Feelings will discomfort, the stagnation of QI with the passing of time and impairing the liver, transverse invasion of hyperactive liver-QI must restrain spleen and violate stomach, causes the mechanism of qi retardance, stomach-QI being unable to descend normally; Stomach and spleen be the exterior and the interior each other, and gastropathy relates in spleen more, and the splenopathy is also often involved stomach, finally causes weakness of the spleen and stomach.In a word, the stomach receiving food and drink digesting food, the various causes of disease cause stagnation of stomach-QI, stomach-QI being unable to descend normally, with the passing of time received become thoroughly decomposed and the transporting and transforming nutrients from foodstuff function neglect one's duty, distension and fullness in the abdomen, pain, vomiting acid regurgitation, indigestion and loss of appetite weak then appear.Total pathogenesis is: stagnation of stomach-QI has the branch of holding wet, dyspepsia, stagnation of liver-QI, insufficiency of the spleen, blood stasis and cold and heat and asthenia and sthenia under the arm again.
The present invention with regulate the flow of vital energy, invigorate blood circulation, the removing dampness spleen invigorating is starting point.At first from soothing the liver the setting about of regulating the flow of vital energy, reuse Caulis Perillae, Rhizoma Cyperi is a monarch drug, Caulis Perillae is gone into the taste warp, and the merit of stronger promoting the circulation of QI to alleviate the stagnation in middle-JIAO is arranged, and controlling the gastral cavilty distension has good effect, and Rhizoma Cyperi goes into Liver Channel, the QI regulating by alleviation of mental depression pain relieving, assistant is removed the merit that expands with the Pericarpium Citri Reticulatae Fructus Aurantii to strengthen regulating the flow of QI to ease the stomach.Pathogen usually intruding into collateral in protracted disease is gone into blood, causes qi depression to blood stasis, occurs based on pain, and localized pain with in the QI regulating medicine, is reused Radix Salviae Miltiorrhizae simply, the pain that disappears of dispelling to invigorate blood circulation.Primary disease is often by due to the eating and drinking without temperance, and stomachache adds with Radix Et Rhizoma Rhei, Semen Raphani, Endothelium Corneum Gigeriae Galli with the passing of time again often because of diet causes dyspepsia accidentally, and stomach falls in dyspepsia and intestinal stasis relieving.Taste are impaired, and the dereliction of duty of transporting and transforming nutrients from foodstuff function has endogenous damp formation more, and the spleen being blocked by dampness is lack of appetite, fatigue and weakness then, reuse Herba Pogostemonis and be aided with Cortex Magnoliae Officinalis, with the fragrance dehumidifying of being amusing, gastropathy was both of a specified duration, often caused coldheat complex, or the vomiting clear water, like warm pain relieved by pressing, or gastric is hot and suffocating, acid regurgitation and epigastric upset just uses Fructus Evodiae, the Radix Linderae with the warming the interior cold expelling, low dose of Rhizoma Coptidis, Radix Sophorae Flavescentis removing damp-heat, and the parasite killing that can detoxify, two class medicines match simultaneously using both cold and hot drugs, pungent drugs can disperse and bitter drugs can descend, the heresy eutopic reduction of dispelling, WEIDE and falling.Taste are empty, a little less than the fortuneization power, reuse tonic and hinder transporting and transforming function of the spleen and stomach on the contrary, so single Radix Astragali simply of using with invigoration spleen qi, and has feeling frustrated of the QI regulating medicine of preventing to consume the fraud of gas.Herba Taraxaci detoxifcation parasite killing, the Pseudobulbus Bletillae (Rhizoma Bletillae) expelling pus and promoting granulation.All medicines match, and gastric qi must be fallen, and temper must rise, and irritability must be transferred, and regulate the flow of vital energy and do not hinder healthy energy, and QI invigorating is and stagnant greasy, and treating both the principal and secondary aspects of a disease, cold and heat decompose, and spleen and stomach function must be answered, and all diseases will cancellation.
For showing curative effect of the present invention, 305 routine patients of treatment are divided into experimental group and matched group execute and control, upright shelves stay to be looked into and follow up survey, is added up contrast.Matched group Chinese medicine and western medicine conventional therapy, test group medicine of the present invention all transfers to well effectively with sx and gastroscopy result; Symptom significantly alleviates or part disappears, and gastroscope shows that it is produce effects that ulcer surface healing, biopsy have the minute quantity helicobacter pylori; All symptoms all disappear, and continue that the gastroscopy ulcer surface has formed cicatrix, biopsy does not have helicobacter pylori, continue more than 1 month, after 1 year not the recidivist be recovery from illness.Statistical result is as follows:
Table 1, matched group curative effect situation:
Figure C9911227300061
Table 2, test group curative effect situation
Figure C9911227300062
Embodiment 1: get Caulis Perillae 30, Rhizoma Cyperi 15, Pericarpium Citri Reticulatae 10, Cortex Magnoliae Officinalis 10, Radix Et Rhizoma Rhei 10, Fructus Aurantii 10, Semen Raphani 30, Radix Salviae Miltiorrhizae 15, Herba Pogostemonis 30, Endothelium Corneum Gigeriae Galli 10, Pseudobulbus Bletillae (Rhizoma Bletillae) 10, Rhizoma Coptidis 10, Fructus Evodiae 3, the Radix Astragali 30, the Radix Linderae 10, Herba Taraxaci 10, Radix Sophorae Flavescentis 6, cure mainly chronic gastritis.With the said medicine mix homogeneously, wear into smalls altogether, thin square-bottomed bamboo basket sieved, incapsulates, every capsule 0.5, each 4-6 grain, every day three times, 30 days is a course of treatment, state of an illness weight person serve on 2-4 the course of treatment.
Embodiment 2: get Caulis Perillae 25, Rhizoma Cyperi 10, Pericarpium Citri Reticulatae 6, Cortex Magnoliae Officinalis 6, Radix Et Rhizoma Rhei 6, Fructus Aurantii 6, Semen Raphani 20, Herba Pogostemonis 20, Radix Salviae Miltiorrhizae 15, Endothelium Corneum Gigeriae Galli 6, Pseudobulbus Bletillae (Rhizoma Bletillae) 10, Rhizoma Coptidis 6, Fructus Evodiae 3, the Radix Astragali 20, the Radix Linderae 6, Herba Taraxaci 10, Radix Sophorae Flavescentis 3, cure mainly peptic ulcer disease, method for making and take method with embodiment 1.

Claims (3)

1, the Chinese patent medicine of treatment chronic gastritis, peptic ulcer disease, it is characterized in that: it is formulated by the following weight proportion raw material:
Caulis Perillae 20-30 Rhizoma Cyperi 10-15 Pericarpium Citri Reticulatae 6-10 Cortex Magnoliae Officinalis 6-10
Radix Et Rhizoma Rhei 6-10 Fructus Aurantii 6-10 Semen Raphani 20-30 Radix Salviae Miltiorrhizae 10-15
Herba Pogostemonis 20-30 Endothelium Corneum Gigeriae Galli 6-10 Pseudobulbus Bletillae (Rhizoma Bletillae) 6-10 Rhizoma Coptidis 6-10
Fructus Evodiae 1-3 Radix Astragali 20-30 Radix Linderae 6-10 Herba Taraxaci 6-10
Radix Sophorae Flavescentis 3-6
2, the Chinese patent medicine of treatment chronic gastritis according to claim 1 is characterized in that: Caulis Perillae 30, Rhizoma Cyperi 15, Pericarpium Citri Reticulatae 10, Cortex Magnoliae Officinalis 10, Radix Et Rhizoma Rhei 10, Fructus Aurantii 10, Semen Raphani 30, Radix Salviae Miltiorrhizae 15, Herba Pogostemonis 30, Endothelium Corneum Gigeriae Galli 10, Pseudobulbus Bletillae (Rhizoma Bletillae) 10, Rhizoma Coptidis 10, Fructus Evodiae 3, the Radix Astragali 30, the Radix Linderae 10, Herba Taraxaci 10, Radix Sophorae Flavescentis 6.
3, the Chinese patent medicine of treatment peptic ulcer disease according to claim 1 is characterized in that: wherein the weight proportion of each raw material is: Caulis Perillae 25, Rhizoma Cyperi 10, Pericarpium Citri Reticulatae 6, Cortex Magnoliae Officinalis 6, Radix Et Rhizoma Rhei 6, Fructus Aurantii 6, Semen Raphani 20, Herba Pogostemonis 20, Radix Salviae Miltiorrhizae 15, Endothelium Corneum Gigeriae Galli 6, Pseudobulbus Bletillae (Rhizoma Bletillae) 10, Rhizoma Coptidis 6, Fructus Evodiae 3, the Radix Astragali 20, the Radix Linderae 6, Herba Taraxaci 10, Radix Sophorae Flavescentis 3.
CN99112273A 1999-06-22 1999-06-22 Chinese patent medicine for treating chronic gastritis and peptic ulcer Expired - Fee Related CN1087622C (en)

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1125642C (en) * 2000-06-14 2003-10-29 邓开仲 Pharmaceutical for treating gastroduodenal ulcer and gastritis, and its prepn. process
CN100358573C (en) * 2005-05-27 2008-01-02 张学军 Medicine composition for treating gastritis, and its prepn. method
CN1330355C (en) * 2005-06-02 2007-08-08 陈贤柱 Chinese medicinal composition for treating ulcer
CN101502561B (en) * 2009-01-09 2011-09-21 黄卫忠 Chinese patent medicine for treating bile reflux gastritis as well as gallbladder disease
CN101502597B (en) * 2009-03-10 2011-06-01 长治市郊区黄碾镇中心卫生院 Medicament for treating stomachache and preparation method thereof
CN105381045A (en) * 2015-12-24 2016-03-09 兰州古驰生物科技有限公司 Traditional Chinese medicine preparation used for treating chronic gastric diseases

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1110591A (en) * 1994-10-21 1995-10-25 孟灵源 Pill for treating gastric vital essence and fluid deficiency type chronic superficial, atrophic gastritis
CN1110924A (en) * 1994-04-28 1995-11-01 余慕良 Effective drug for gastric disease
CN1140080A (en) * 1996-01-25 1997-01-15 李道新 Stomach-recovering capsule
CN1141782A (en) * 1995-08-03 1997-02-05 张鸿毓 Ready-made Chinese medicine for treatment of stomach trouble

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1110924A (en) * 1994-04-28 1995-11-01 余慕良 Effective drug for gastric disease
CN1110591A (en) * 1994-10-21 1995-10-25 孟灵源 Pill for treating gastric vital essence and fluid deficiency type chronic superficial, atrophic gastritis
CN1141782A (en) * 1995-08-03 1997-02-05 张鸿毓 Ready-made Chinese medicine for treatment of stomach trouble
CN1140080A (en) * 1996-01-25 1997-01-15 李道新 Stomach-recovering capsule

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