CN108743851A - A kind of preparation method and compound probiotic powder of compound probiotic powder - Google Patents
A kind of preparation method and compound probiotic powder of compound probiotic powder Download PDFInfo
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Abstract
The invention discloses a kind of preparation methods of compound probiotic powder, include the following steps：Weighing：By weight, 0.5~2.5 part of 400~1200 parts of blueberry juice, 140~300 parts of maltodextrin, 120~250 parts of maltitol, 4~10 parts of wrinkled giant hyssop, 2~6 parts of Poria cocos, 2~6 parts of malt, 2~6 parts of sophora flower, 0.5~2.5 part of lactobacillus acidophilus bacterium powder, 0.2~1 part of bifidobacterium lactis bacterium powder and Lactobacillus rhamnosus bacterium powder are weighed；Compounding；Fermentation and freeze-drying.The invention also discloses a kind of compound probiotic powder.A kind of preparation method of compound probiotic powder of the present invention, the beneficial metabolic product etc. that the compound probiotic powder prepared by this method is generated rich in probiotics, active ingredient of Chinese herbs, probiotics metabolism, the compound probiotic powder is taken orally by infant, reaches conditioning infant intestinal microflora, improves digestive function and appetite, promotes the functions such as infant immunity.
Description
Technical field
The present invention relates to functional health-care food and field of pharmaceutical technology, more particularly to one kind having improvement infant's enteron aisle
The preparation method of the compound probiotic powder of dysfunction, malnutrition and raising infant immunity, and by above-mentioned compound
Compound probiotic powder made from the preparation method of probiotic powder.
Background technology
Intestinal flora, the microflora in human body intestinal canal, such as Bifidobacterium, Bacillus acidi lactici and lactobacillus can synthesize
A variety of growth in humans develop necessary vitamin, vitamin K, niacin, general such as B family vitamin (vitamin B1, B2, B6, B12)
Acid etc., moreover it is possible to protein residue synth essential amino acid, such as asparagus fern door propylhomoserin, phenylalanine, valine and threonine are utilized,
And the metabolism of carbohydrate and protein is participated in, while the absorption of the mineral elements such as iron, magnesium, zinc can also be promoted.These nutriments pair
The healthy important role of the mankind, once a variety of diseases can be caused by lacking.Except substance synthesis is in addition to metabolic function, enteron aisle is complicated
Microbial ecosystem and body immune system between relationship also extremely closely.Enteric microorganism acts not only as naturally
Barrier maintains the integrality of enteric epithelium, prevents pathogenic microorganism from invading, and also acts on intestines by adjusting intestinal mucosa secretory antibody
Road immune system, and the innate immunity and acquired immunity are further influenced, therefore enteric microorganism is considered as human body maximum again
" immune organ ".The immunologic balance that enteric microorganism maintains plays important work during the prevention of body autoimmune disease
With, when certain factors cause intestinal flora to change, other immune systems of people can be further influenced, it is this immune flat
Weighing apparatus is easy for leading to the generation of various diseases once being broken.More and more experimental evidences show enteric microorganism not only shadow
The function of human body intestinal canal itself is rung, also by regulating and controlling the immune system of people, influences the health of people with level from different perspectives.
Infantile period is the first peak period of human life's growth and development, simultaneous infant's intestinal flora it is rapid
It establishes.On the other hand on the one hand microorganism that the foundation of infant's intestinal flora suspends in air also derives from infant
Early period feed, the probiotics of especially above-mentioned anaerobic type.How infant rapidly to be helped to set up perfect intestinal colony
System improves disorderly infant's function of intestinal canal and malnutrition, improves infant immunity, becomes current health care of food science neck
The a great problem that domain faces.
Invention content
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide a kind of preparations of compound probiotic powder
Method, the compound probiotic powder prepared by the preparation method of the compound probiotic powder, to solve the enteron aisle of infant's appearance
The problems such as bacterium colony system is unsound, function of intestinal canal is disorderly, malnutritive and hypoimmunity.
The second object of the present invention is to provide a kind of compound probiotic powder, by taking orally the compound probiotic powder, to
Solve the problems such as intestinal colony system that infant occurs is unsound, function of intestinal canal is disorderly, malnutritive and hypoimmunity.
An object of the present invention adopts the following technical scheme that realization：
A kind of preparation method of compound probiotic powder, includes the following steps：
Weighing：By weight, 400~1200 parts of blueberry juice, 140~300 parts of maltodextrin, maltitol 120 are weighed
~250 parts, 4~10 parts of wrinkled giant hyssop, 2~6 parts of Poria cocos, 2~6 parts of malt, 2~6 parts of sophora flower, lactobacillus acidophilus bacterium powder 0.5~2.5
0.5~2.5 part of part, 0.2~1 part of bifidobacterium lactis bacterium powder and Lactobacillus rhamnosus bacterium powder；
Compounding：It will be added to sterile indigo plant after the sterilizing of maltodextrin, maltitol, wrinkled giant hyssop, Poria cocos, malt and sophora flower
It in certain kind of berries juice, is uniformly mixed, then adds lactobacillus acidophilus bacterium powder, bifidobacterium lactis bacterium powder and Lactobacillus rhamnosus into blueberry juice
Bacterium powder；
Fermentation：At the uniform velocity under stirring state, anaerobic fermentation 1~5 day under the conditions of 35~40 DEG C is double-deck after anaerobic fermentation
Filtered through gauze obtains filtrate；
Freeze-drying：Concentrating filter liquor, freeze-drying are finally crushed to 80~120 mesh fineness, and compound probiotic powder is made.
Further, in weighing step, the blueberry juice is 600~1000 parts, and the maltodextrin is 180~250
Part, the maltitol is 160~220 parts, and the wrinkled giant hyssop is 6~8 parts, and the Poria cocos is 3~5 parts, and the malt is 3~4
Part, the sophora flower is 3~5 parts, and the lactobacillus acidophilus bacterium powder is 1~2 part, and the bifidobacterium lactis bacterium powder is 0.4~0.7
Part, the Lactobacillus rhamnosus bacterium powder is 1~2.2 part.
Further, in weighing step, the blueberry juice is 800 parts, and the maltodextrin is 220 parts, the malt
Sugar alcohol is 185 parts, and the wrinkled giant hyssop is 7 parts, and the Poria cocos is 4 parts, and the malt is 3.5 parts, and the sophora flower is 4.5 parts, described
Lactobacillus acidophilus bacterium powder is 1.5 parts, and the bifidobacterium lactis bacterium powder is 0.6 part, and the Lactobacillus rhamnosus bacterium powder is 1.8 parts.
Further, in compounding step, wrinkled giant hyssop, Poria cocos, malt and sophora flower are crushed to 5~30 mesh fineness, by powder
It is added in 500~1000 parts of purified waters together with broken wrinkled giant hyssop, Poria cocos, malt and sophora flower and maltodextrin, maltitol, 95~
108 DEG C of gelatinizations, sterilizing and water carry 0.5~4h, obtain compounding mixed liquor, and compounding mixed liquor is used to be inoculated with acidophilus after mixing with blueberry juice
Lactobacillus bacterium powder, bifidobacterium lactis bacterium powder and Lactobacillus rhamnosus bacterium powder.
Further, the wrinkled giant hyssop, Poria cocos, malt and sophora flower are crushed to 10~20 mesh fineness, and the purified water is 600
~800 parts, the temperature that the gelatinization, sterilizing and water carry is 105 DEG C, and the time that the gelatinization, sterilizing and water carry is 2.5h.
Further, in fermentation step, the temperature of the anaerobic fermentation is 38 DEG C, and the time of the anaerobic fermentation is 3
It.
Further, in fermentation step, zymotic fluid carries out the at the uniform velocity stirring of 120~200r/min.
Further, in step of freeze drying, vacuum and low temperature concentrates under the conditions of the concentration is 25~35 DEG C, and the freezing is dry
Dry temperature is -20~-40 DEG C, and the vacuum degree of the freeze-drying is 500~1500millitorr.
Further, in step of freeze drying, the moisture of the compound probiotic powder is 12%~16%.
The second object of the present invention adopts the following technical scheme that realization：
A kind of compound probiotic powder, the compound probiotic powder by compound probiotic powder described in any one of the above embodiments preparation
Method is prepared.
Compared with prior art, the beneficial effects of the present invention are：
(1) a kind of preparation method of compound probiotic powder of the present invention, the compound probiotic powder prepared by this method are rich in
The beneficial metabolic product etc. that probiotics, active ingredient of Chinese herbs, probiotics metabolism generate, the compound probiotic is taken orally by infant
Powder reaches conditioning infant intestinal microflora, improves digestive function and appetite, promotes the functions such as infant immunity.
(2) a kind of compound probiotic powder of the present invention, have conditioning infant intestinal microflora, improve digestive function,
It promotes appetite, promote the functions such as infant immunity and resistance, hence it is evident that reduce the number that infant catches a cold.
Specific implementation mode
In the following, in conjunction with specific implementation mode, the present invention is described further, it should be noted that is do not collided
Under the premise of, new embodiment can be formed between various embodiments described below or between each technical characteristic in any combination.
Hereinafter, illustrating a kind of preparation process of compound probiotic powder of the present invention by Examples 1 to 6.
Examples 1 to 6 is 6 kinds of different compound probiotic powder, and the preparation process of this 6 kinds different compound probiotic powder is equal
Including weighing step, compounding step, fermentation step and step of freeze drying.The preparation process of this 6 kinds different compound probiotic powder
Difference be only that raw material proportioning and the difference of technological parameter.
Weighing step：By weight, weigh blueberry juice, maltodextrin, maltitol, wrinkled giant hyssop, Poria cocos, malt, sophora flower,
Lactobacillus acidophilus bacterium powder, bifidobacterium lactis bacterium powder and Lactobacillus rhamnosus bacterium powder.The weight proportion of each raw material is shown in Table 1.
Table 1
Compound step：The wrinkled giant hyssop weighed, Poria cocos, malt and sophora flower are crushed to certain fineness, then by the wrinkled giant hyssop of crushing,
It is added in 500~1000 parts of purified waters, is uniformly mixed together with Poria cocos, malt and sophora flower and maltodextrin, maltitol,
Under certain temperature to wrinkled giant hyssop, Poria cocos, malt with, sophora flower, maltodextrin and maltitol powder be gelatinized, sterilized and water carries,
Mixed liquor must be compounded after sterilizing.Meanwhile ozone sterilization is carried out to blueberry juice, sterile blueberry juice is made.It finally will compounding
Mixed liquor is uniformly mixed with sterile blueberry juice, adds lactobacillus acidophilus bacterium powder in above-mentioned weighing step, bifidobacterium lactis bacterium
Powder and Lactobacillus rhamnosus bacterium powder.Wrinkled giant hyssop, Poria cocos, malt and the smashing fineness of sophora flower, amount of water, sterilising temp, sterilizing
The circulation of ozone, ozone sterilization time etc., parameters were shown in Table 2 in time, ozone sterilization.
Table 2
Fermentation step：At the uniform velocity under stirring state, anaerobic fermentation 5~10 days under the conditions of 35~40 DEG C, after anaerobic fermentation,
Double gauze filters to get filtrate.The filtrate includes three kinds of lactobacillus acidophilus, bifidobacterium lactis and Lactobacillus rhamnosus viable bacteria bacterium
Body.The parameters such as speed of agitator, anaerobic fermentation temperature, anaerobic fermentation time are referring to table 3.
Table 3
Step of freeze drying：The filtrate obtained in above-mentioned fermentation step concentrates through low temperature, freeze-drying, finally it is crushed to 80~
Compound probiotic powder is made in 120 mesh fineness.Pass through the water content of direct drying method test compound probiotic powder.Low temperature concentration
Temperature and vacuum degree, the temperature of the freeze-drying and parameters such as vacuum degree and the water content of compound probiotic powder are referring to table 4.
Table 4
Effect test 1：Effect of the test compound probiotic powder of the present invention to constipation of infantile
Constipation of infantile criterion：1. stool amount less, it is dry, be in sheep manure ball sample sometimes, landing is sound；2. difficulty in defecation with
, there are the expression of pain in discharge, when defecation, or even have the case where anus is bursting at the collision；3. abdomen turgor, pain；4. anorexia is tired of
It is hot-tempered, temperish.
The infant that 140 clinical diagnosises are constipation is chosen, age distribution ranging from -3 years old 3 months is randomly divided into 7 groups,
It is experimental group A, experimental group B, experimental group C, experimental group D, experimental group E, experimental group F and control group, the baby of every group of constipation respectively
Child is 20.Test method：The infant of experimental group A is brewed by 30~40 DEG C of warm water 100ml compound in embodiment 1 daily
Probiotic powder 20g is simultaneously completed oral；The infant of experimental group B is brewed by 30~40 DEG C of warm water 100ml multiple in embodiment 2 daily
It closes probiotic powder 20g and completes oral；The infant of experimental group C is brewed by 30~40 DEG C of warm water 100ml in embodiment 3 daily
Compound probiotic powder 20g is simultaneously completed oral；The infant of experimental group D brews embodiment 4 by 30~40 DEG C of warm water 100ml daily
Middle compound probiotic powder 20g is simultaneously completed oral；The infant of experimental group E brews implementation by 30~40 DEG C of warm water 100ml daily
It compound probiotic powder 20g and is completed oral in example 5；The infant of experimental group F brews reality by 30~40 DEG C of warm water 100ml daily
It applies compound probiotic powder 20g in example 6 and completes oral；The infant of control group takes orally 30~40 DEG C of warm water 100ml daily.Except upper
Except stating, other eating habits are consistent and suitable with normal diet.It keeps above-mentioned diet (experiment) two weeks, unites after two weeks
The constipation situation for counting 140 infants, the results are shown in Table 5.
Clinical efficacy criterion
Recovery from illness：Defecation is smooth, soft but normal shape of defecating.
Improve：Symptom improves, but does not completely disappear.
In vain：Dry and hard excrement, defecation are laborious.
Total effective rate=(recovery from illness number+improvement number) ÷ 20 × 100%.
Table 5
By 5 result of above-mentioned table it is found that compared to control group, compound probiotic powder of the present invention is improving constipation of infantile situation
Aspect significant effect, total effective rate can be effectively improved constipation of infantile situation more than 95%.Wherein, prepared by embodiment 3
Compound probiotic powder best results in terms of improving constipation of infantile situation.
Effect test 2：Effect of the test compound probiotic powder of the present invention to infantile diarrhea
The criterion of infantile diarrhea：Times of defecation increases than usual, and stool changes, and in loose stools, watery stool, glues
Liquid just and pus and blood stool, can be with the symptoms such as Nausea and vomiting, abdominal pain, fever, thirsty.
Experiment crowd：Choose the infant that 140 clinical diagnosises are diarrhea, age distribution ranging from -3 years old 3 months, at random
It is divided into 7 groups, is experimental group A, experimental group B, experimental group C, experimental group D, experimental group E, experimental group F and control group respectively, every group
The infant of constipation is 20.Test method is identical as said effect experiment 1.Keep above-mentioned diet (experiment) two weeks, after two weeks
The diarrhea situation for counting 140 infants, the results are shown in Table 6.
Clinical efficacy criterion
Recovery from illness：Shape of defecating is normal, and times of defecation is reduced.
Improve：Symptom improves, but does not completely disappear.
In vain：Stool routine examination has leucocyte, can have fat globule with/without red blood cell with/without pyocyte.Stool cause of disease physical examination
Enteropathogenic E. Coli or the virus checking positive etc. can be had by looking into.
Total effective rate=(recovery from illness number+improvement number) ÷ 20 × 100%.
Table 6
By 6 result of above-mentioned table it is found that compound probiotic powder of the present invention can be effectively improved infantile diarrhea situation, relative to
Control group, receiving to take orally the infantile diarrhea situation of compound probiotic powder of the present invention improves obviously, and total effective rate is more than 95%.Its
In, embodiment 3 prepare compound probiotic powder in terms of improving infantile diarrhea situation best results.
Effect test 3：The effect that test compound probiotic powder of the present invention promotes infant immunity.
Total 280 infants catch a cold in 60 days total after the end of the test in statistics effect test 1 and effect test 2
Number (summation that all treating baby's cold numbers are added in each group) and flu incidence (the total degree ÷ of each group of flu
Panel size × 100%).Wherein, the compound probiotic powder that prepared by embodiment 1-6 corresponds to 40 infants, and control group is same
Corresponding 40 infants.Statistical result is shown in Table 7.
Table 7
By 7 result of above-mentioned table it is found that compound probiotic powder of the present invention can effectively reduce infant catches a cold number, promoted
Immunity of organisms resists germ or virus attack.Wherein, the compound probiotic powder that prepared by embodiment 3 is promoting infant's machine
Body immunity, reduction effect in terms of number of catching a cold are the most notable.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto,
The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed range.
Claims (10)
1. a kind of preparation method of compound probiotic powder, which is characterized in that include the following steps：
Weighing：By weight, 400~1200 parts of blueberry juice, 140~300 parts of maltodextrin, maltitol 120~250 are weighed
Part, 4~10 parts of wrinkled giant hyssop, 2~6 parts of Poria cocos, 2~6 parts of malt, 2~6 parts of sophora flower, 0.5~2.5 part of lactobacillus acidophilus bacterium powder, breast are double
0.5~2.5 part of 0.2~1 part of discrimination bacillus bacterium powder and Lactobacillus rhamnosus bacterium powder；
Compounding：It will be added to sterile blueberry juice after the sterilizing of maltodextrin, maltitol, wrinkled giant hyssop, Poria cocos, malt and sophora flower
In, it is uniformly mixed, then lactobacillus acidophilus bacterium powder, bifidobacterium lactis bacterium powder and Lactobacillus rhamnosus bacterium are added into blueberry juice
Powder；
Fermentation：At the uniform velocity under stirring state, anaerobic fermentation 1~5 day under the conditions of 35~40 DEG C, after anaerobic fermentation, double gauze
It filters to get filtrate；
Freeze-drying：Concentrating filter liquor, freeze-drying are finally crushed to 80~120 mesh fineness, and compound probiotic powder is made.
2. the preparation method of compound probiotic powder as described in claim 1, which is characterized in that in weighing step, the indigo plant
Certain kind of berries juice is 600~1000 parts, and the maltodextrin is 180~250 parts, and the maltitol is 160~220 parts, the wrinkled giant hyssop
It it is 6~8 parts, the Poria cocos is 3~5 parts, and the malt is 3~4 parts, and the sophora flower is 3~5 parts, the lactobacillus acidophilus bacterium
Powder is 1~2 part, and the bifidobacterium lactis bacterium powder is 0.4~0.7 part, and the Lactobacillus rhamnosus bacterium powder is 1~2.2 part.
3. the preparation method of compound probiotic powder as claimed in claim 2, which is characterized in that in weighing step, the indigo plant
Certain kind of berries juice is 800 parts, and the maltodextrin is 220 parts, and the maltitol is 185 parts, and the wrinkled giant hyssop is 7 parts, and the Poria cocos is 4
Part, the malt is 3.5 parts, and the sophora flower is 4.5 parts, and the lactobacillus acidophilus bacterium powder is 1.5 parts, the bifidobacterium lactis bacterium
Powder is 0.6 part, and the Lactobacillus rhamnosus bacterium powder is 1.8 parts.
4. the preparation method of compound probiotic powder as described in claim 1, which is characterized in that in compounding step, by wrinkled giant hyssop,
Poria cocos, malt and sophora flower are crushed to 5~30 mesh fineness, by the wrinkled giant hyssop of crushing, Poria cocos, malt and sophora flower and maltodextrin, wheat
Bud sugar alcohol is added to together in 500~1000 parts of purified waters, and 95~108 DEG C of gelatinizations, sterilizing and water carry 0.5~4h, must be compounded mixed
Liquid is closed, compounding mixed liquor is used for inoculating lactobacillus acidophilus' bacterium powder, bifidobacterium lactis bacterium powder and rhamnose after being mixed with blueberry juice
Lactobacillus bacterium powder.
5. the preparation method of compound probiotic powder as claimed in claim 4, which is characterized in that the wrinkled giant hyssop, Poria cocos, malt with
And sophora flower is crushed to 10~20 mesh fineness, the purified water is 600~800 parts, and the temperature that the gelatinization, sterilizing and water carry is
105 DEG C, the time that the gelatinization, sterilizing and water carry is 2.5h.
6. the preparation method of compound probiotic powder as described in claim 1, which is characterized in that in fermentation step, the nothing
The temperature of aerobe fermentation is 38 DEG C, and the time of the anaerobic fermentation is 3 days.
7. the preparation method of compound probiotic powder as claimed in claim 6, which is characterized in that in fermentation step, zymotic fluid
Carry out the at the uniform velocity stirring of 120~200r/min.
8. the preparation method of compound probiotic powder as described in claim 1, which is characterized in that described dense in step of freeze drying
Vacuum and low temperature concentrates under the conditions of being condensed to 25~35 DEG C, and the temperature of the freeze-drying is -20~-40 DEG C, the freeze-drying
Vacuum degree is 500~1500millitorr.
9. the preparation method of compound probiotic powder as claimed in claim 8, which is characterized in that described multiple in step of freeze drying
The moisture for closing probiotic powder is 12%~16%.
10. a kind of compound probiotic powder, which is characterized in that the compound probiotic powder is by claim 1-9 any one of them
The preparation method of compound probiotic powder is prepared.
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Cited By (11)
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| CN109479972A (en) * | 2018-12-10 | 2019-03-19 | 石家庄君乐宝乳业有限公司 | Improve the baby milk powder companion and preparation method thereof of gastrointestinal tract |
| CN110250389A (en) * | 2019-07-16 | 2019-09-20 | 新绎健康管理有限公司 | A kind of the compound probiotic solid beverage and preparation method of auxiliary adjustment blood pressure and blood lipoid |
| IT201900016850A1 (en) * | 2019-09-20 | 2021-03-20 | Sofar Spa | Compositions based on bacterial strains and berry extracts and their use as anti-inflammatories |
| CN115011650A (en) * | 2022-07-21 | 2022-09-06 | 石家庄市惠源淀粉有限公司 | Preparation method of medicinal brown maltodextrin |
| US11464814B2 (en) | 2014-04-23 | 2022-10-11 | Sofar Spa | Topical composition for use in the treatment of inflammatory bowel disease |
| US11591416B2 (en) | 2016-12-02 | 2023-02-28 | Sofar S.P.A. | Exopolysaccharides and uses thereof |
| CN116114869A (en) * | 2022-12-23 | 2023-05-16 | 安徽九鑫药业有限公司 | Probiotics calcium-iron-zinc powder |
| US11752179B2 (en) | 2016-06-08 | 2023-09-12 | Alfasigma S.P.A. | Medical use of probiotics |
| US11751597B2 (en) | 2019-11-05 | 2023-09-12 | Alfasigma S.P.A. | Compositions comprising bacterial strains for use in increasing the bioavailability of amino acids derived from proteins, and related food product methods and systems |
| US11839634B2 (en) | 2013-09-06 | 2023-12-12 | Alfasigma S.P.A. | Use of a composition comprising microorganisms to increase the intestinal production of butyric acid, folic acid or niacin and/or decrease the intestinal production of succinic acid |
| US11896631B2 (en) | 2016-12-16 | 2024-02-13 | Alfasigma S.P.A. | Probiotics for use in the treatment of diverticulosis and diverticular disease |
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| CN103623293A (en) * | 2012-08-24 | 2014-03-12 | 河源信天然营养品有限公司 | Micro-ecological oral preparation |
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| CN103623293A (en) * | 2012-08-24 | 2014-03-12 | 河源信天然营养品有限公司 | Micro-ecological oral preparation |
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| US11839634B2 (en) | 2013-09-06 | 2023-12-12 | Alfasigma S.P.A. | Use of a composition comprising microorganisms to increase the intestinal production of butyric acid, folic acid or niacin and/or decrease the intestinal production of succinic acid |
| US11464814B2 (en) | 2014-04-23 | 2022-10-11 | Sofar Spa | Topical composition for use in the treatment of inflammatory bowel disease |
| US11752179B2 (en) | 2016-06-08 | 2023-09-12 | Alfasigma S.P.A. | Medical use of probiotics |
| US11591416B2 (en) | 2016-12-02 | 2023-02-28 | Sofar S.P.A. | Exopolysaccharides and uses thereof |
| US11896631B2 (en) | 2016-12-16 | 2024-02-13 | Alfasigma S.P.A. | Probiotics for use in the treatment of diverticulosis and diverticular disease |
| CN109479972A (en) * | 2018-12-10 | 2019-03-19 | 石家庄君乐宝乳业有限公司 | Improve the baby milk powder companion and preparation method thereof of gastrointestinal tract |
| CN110250389A (en) * | 2019-07-16 | 2019-09-20 | 新绎健康管理有限公司 | A kind of the compound probiotic solid beverage and preparation method of auxiliary adjustment blood pressure and blood lipoid |
| WO2021053641A3 (en) * | 2019-09-20 | 2021-05-20 | Sofar S.P.A. | Compositions based on bacterial strains and berry extracts and their use as anti-inflammatories |
| CN114728033A (en) * | 2019-09-20 | 2022-07-08 | 索法尔公司 | Composition based on bacterial strains and berry extract and its use as anti-inflammatory agent |
| IT201900016850A1 (en) * | 2019-09-20 | 2021-03-20 | Sofar Spa | Compositions based on bacterial strains and berry extracts and their use as anti-inflammatories |
| US11751597B2 (en) | 2019-11-05 | 2023-09-12 | Alfasigma S.P.A. | Compositions comprising bacterial strains for use in increasing the bioavailability of amino acids derived from proteins, and related food product methods and systems |
| CN115011650A (en) * | 2022-07-21 | 2022-09-06 | 石家庄市惠源淀粉有限公司 | Preparation method of medicinal brown maltodextrin |
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