CN108721546A - A kind of sprayer formulation for treating asthma - Google Patents

A kind of sprayer formulation for treating asthma Download PDF

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Publication number
CN108721546A
CN108721546A CN201810937749.7A CN201810937749A CN108721546A CN 108721546 A CN108721546 A CN 108721546A CN 201810937749 A CN201810937749 A CN 201810937749A CN 108721546 A CN108721546 A CN 108721546A
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Prior art keywords
tuber
root
asthma
osbeckia
stemona
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CN201810937749.7A
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Chinese (zh)
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刘凌华
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams

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  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
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Abstract

The invention discloses a kind of sprayer formulations for treating asthma, are made of loguat leaf, the tuber of pinellia, aster, the tuber of stemona, honeysuckle, dandelion, common bombax flower, chamomile, lepidium seed, wrinkled giant hyssop, PORIA ALBA, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and almond；Compared with prior art, the present invention has effects that clearing heat and detoxicating, clearing damp dissipating bind, moistening lung for removing phlegm cough-relieving, has good therapeutic effect to asthma, rapid-action, uneasy to recur, has the value of popularization and application.

Description

A kind of sprayer formulation for treating asthma
Technical field
The present invention relates to technical field of pharmaceuticals more particularly to a kind of sprayer formulations for treating asthma.
Background technology
Asthma also known as bronchial asthma.Bronchial asthma is the chronic airway inflammation participated in by various kinds of cell and cellular component Disease, such inflammation lead to the panting of recurrent exerbation, shortness of breath, uncomfortable in chest and (or) cough etc. often with causing airway reactivity to increase Symptom mostly occurs in night and (or) morning, and such symptom is often accompanied by extensive and changeable airflow obstruction, can voluntarily or pass through It treats and reverses.
Invention content
The purpose of the present invention is that solve the above-mentioned problems and provides a kind of sprayer formulation for treating asthma.
The present invention is achieved through the following technical solutions above-mentioned purpose：
The present invention is by loguat leaf, the tuber of pinellia, aster, the tuber of stemona, honeysuckle, dandelion, common bombax flower, chamomile, lepidium seed, the leaves of pulse plants Perfume, PORIA ALBA, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and almond are made；
Specific preparation method includes the following steps：
(1) by the loguat leaf, tuber of pinellia, aster, the tuber of stemona, honeysuckle, dandelion, common bombax flower, chamomile, lepidium seed, wrinkled giant hyssop, white Poria cocos, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and almond are milled after being dried；
(2) water that the medicinal powder after milling is added to 5 times of amounts boils, and turns slow boiling slowly 30 points of tanning after ebuillition of heated Clock；
(3) boiled drug is filtered, takes juice；
(4) filtered concoction is staticly settled,
(5) supernatant is taken to be packaged in spray medicine bottle up to the spray of asthma is treated after precipitating.
Preferably, by weight percentage, every part containing the loguat leaf 7%, tuber of pinellia 2%, the aster 3%, described The tuber of stemona 9%, the honeysuckle 12%, the dandelion 6%, the common bombax flower 6%, the chamomile 6%, the lepidium seed 5%, the wrinkled giant hyssop 5%, the PORIA ALBA 8%, the root bark of Chinese wolf-berry 7%, the osbeckia 9%, the Radix Glycyrrhizae 2%, the fish Raw meat grass 2%, the fritillaria thunbergii 3%, the root of purple-flowered peucedanum 3%, the almond 5%.
The beneficial effects of the present invention are：
The present invention is a kind of sprayer formulation for treating asthma, compared with prior art, the present invention have it is clearing heat and detoxicating, dispel , there is good therapeutic effect in the effect of wet dissipating bind, moistening lung for removing phlegm cough-relieving to asthma, rapid-action, uneasy to recur, has and promotes and applies Value.
Specific implementation mode
The invention will be further described below：
The present invention is by loguat leaf, the tuber of pinellia, aster, the tuber of stemona, honeysuckle, dandelion, common bombax flower, chamomile, lepidium seed, the leaves of pulse plants Perfume, PORIA ALBA, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and almond are made；
Specific preparation method includes the following steps：
(1) by the loguat leaf, tuber of pinellia, aster, the tuber of stemona, honeysuckle, dandelion, common bombax flower, chamomile, lepidium seed, wrinkled giant hyssop, white Poria cocos, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and almond are milled after being dried；
(2) water that the medicinal powder after milling is added to 5 times of amounts boils, and turns slow boiling slowly 30 points of tanning after ebuillition of heated Clock；
(3) boiled drug is filtered, takes juice；
(4) filtered concoction is staticly settled,
(5) supernatant is taken to be packaged in spray medicine bottle up to the spray of asthma is treated after precipitating.
Preferably, by weight percentage, every part containing the loguat leaf 7%, tuber of pinellia 2%, the aster 3%, described The tuber of stemona 9%, the honeysuckle 12%, the dandelion 6%, the common bombax flower 6%, the chamomile 6%, the lepidium seed 5%, the wrinkled giant hyssop 5%, the PORIA ALBA 8%, the root bark of Chinese wolf-berry 7%, the osbeckia 9%, the Radix Glycyrrhizae 2%, the fish Raw meat grass 2%, the fritillaria thunbergii 3%, the root of purple-flowered peucedanum 3%, the almond 5%.
In treatment, to patient using the drug of the present invention, 3 times a day, spray 3-4 times toward throat every time.Continuously After 2 weeks, therapeutic effect is observed.Curative effect judges effective：The Severe Asthmas symptoms such as patient is uncomfortable in chest, pectoralgia, expiratory dyspnea are complete Alleviate, there is mild episode only with milds such as coughs, to be not required to medication once in a while；Effectively：Symptom is apparent when patient's asthma attack Mitigate, and attack times are also reduced；In vain：Patient's asthma symptoms are without mitigation after medication.
The basic principles and main features and advantages of the present invention of the present invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (2)

1. a kind of sprayer formulation for treating asthma, it is characterised in that：By loguat leaf, the tuber of pinellia, aster, the tuber of stemona, honeysuckle, Pu Gong English, common bombax flower, chamomile, lepidium seed, wrinkled giant hyssop, PORIA ALBA, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and apricot Benevolence is made；
Specific preparation method includes the following steps：
(1) by loguat leaf, the tuber of pinellia, aster, the tuber of stemona, honeysuckle, dandelion, common bombax flower, chamomile, lepidium seed, wrinkled giant hyssop, white Fu Siberian cocklebur, the root bark of Chinese wolf-berry, osbeckia, Radix Glycyrrhizae, cordate houttuynia, fritillaria thunbergii, the root of purple-flowered peucedanum and almond are milled after being dried；
(2) water that the medicinal powder after milling is added to 5 times of amounts boils, and turns slow boiling slowly tanning 30 minutes after ebuillition of heated；
(3) boiled drug is filtered, takes juice；
(4) filtered concoction is staticly settled,
(5) supernatant is taken to be packaged in spray medicine bottle up to the spray of asthma is treated after precipitating.
2. the sprayer formulation for the treatment of asthma according to claim 1, it is characterised in that：By weight percentage, contain for every part The loguat leaf 7%, the tuber of pinellia 2%, the aster 3%, the tuber of stemona 9%, the honeysuckle 12%, the dandelion 6%, the common bombax flower 6%, chamomile 6%, the lepidium seed 5%, the wrinkled giant hyssop 5%, the PORIA ALBA 8%, described The root bark of Chinese wolf-berry 7%, the osbeckia 9%, the Radix Glycyrrhizae 2%, the cordate houttuynia 2%, the fritillaria thunbergii 3%, the root of purple-flowered peucedanum 3%, The almond 5%.
CN201810937749.7A 2018-08-17 2018-08-17 A kind of sprayer formulation for treating asthma Pending CN108721546A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103463517A (en) * 2013-09-26 2013-12-25 孙凡景 Medicament for treating asthma
CN103463538A (en) * 2013-09-26 2013-12-25 孙凡景 Asthma medicine
CN104971207A (en) * 2015-07-25 2015-10-14 曹健 Traditional Chinese medicine preparation for treating asthma
CN105497358A (en) * 2014-09-24 2016-04-20 潘旭丽 Asthma treating drug
CN108079145A (en) * 2016-11-22 2018-05-29 周丽 A kind of drug for treating asthma

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103463517A (en) * 2013-09-26 2013-12-25 孙凡景 Medicament for treating asthma
CN103463538A (en) * 2013-09-26 2013-12-25 孙凡景 Asthma medicine
CN105497358A (en) * 2014-09-24 2016-04-20 潘旭丽 Asthma treating drug
CN104971207A (en) * 2015-07-25 2015-10-14 曹健 Traditional Chinese medicine preparation for treating asthma
CN108079145A (en) * 2016-11-22 2018-05-29 周丽 A kind of drug for treating asthma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
姜丕政等: "泻肺定喘方治疗支气管哮喘疗效观察", 《中医药学刊》 *
翟熙君: "支气管哮喘辨治思路", 《河南中医》 *

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Application publication date: 20181102