CN108721534A - 一种治疗口舌生疮的中药制剂 - Google Patents

一种治疗口舌生疮的中药制剂 Download PDF

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CN108721534A
CN108721534A CN201710275600.2A CN201710275600A CN108721534A CN 108721534 A CN108721534 A CN 108721534A CN 201710275600 A CN201710275600 A CN 201710275600A CN 108721534 A CN108721534 A CN 108721534A
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郝纪涛
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Abstract

本发明涉及一种治疗口舌生疮的中药制剂，各原料的重量组成为：生熟地15克、山药30克、萸肉10克、泽泻15克、玄参20克、丹皮12克、茵陈30克、炒山栀12克、黄连12克、半夏12克、沙参20克、寸冬15克、蒲公英30克、枇杷叶20克、连翘20克、射干15克、神曲30克、炒麦芽30克、磁石15克、甘草6克。本发明具有治疗口舌生疮功效，具有见效快、疗效高、安全方便、无毒副作用等特点。

Description

一种治疗口舌生疮的中药制剂
技术领域
本发明涉及一种口舌生疮的中药制剂，属中医中药技术领域。
背景技术
本病的主要症状是口腔黏膜反复出现圆形或椭圆形小溃疡，可单发或多发在口腔黏膜的任何部分，有剧烈的自发痛，一般在10天左右可自愈。局部症状比较显著，全身症状多不明显。愈合不留任何瘢痕，但可以反复发作。好发于青壮年，女性多于男性。发病时唇、颏、舌边缘、牙龈等处出现孤立的圆形成椭圆形成浅层小溃疡，有的同时多处发生。疼痛剧烈似烧灼样。随天气、情绪、劳累等因素可复发。 多由心脾积热，外感热邪，或脾胃湿热，阴虚阳亢所致。
发明内容
本发明的目的是提供一种治疗口舌生疮的中药制剂，具有疗效确切、见效快、疗效高、疗程短、安全方便等特点。
本发明治疗口舌生疮的中药制剂，各中药原料的重量组成为：生熟地15克、山药30克、萸肉10克、泽泻15克、玄参20克、丹皮12克、茵陈30克、炒山栀12克、黄连12克、半夏12克、沙参20克、寸冬15克、蒲公英30克、枇杷叶20克、连翘20克、射干15克、神曲30克、炒麦芽30克、磁石15克、甘草6克。
本发明中的药物机理如下：
生熟地：生熟地又名干地黄，性味甘、苦、寒，具有清热凉血、养阴生津之功效，为清热凉血药。用于温热病热入营血，身热口干、舌绛或红等症状，如清营汤；用于热在血分，迫血妄行的吐血、尿血、崩漏下血等症状。
山药：山药具有滋养强壮，助消化，敛虚汗，止泻之功效，主治脾虚腹泻、肺虚咳嗽、糖尿病消渴、小便短频、遗精、妇女带下及消化不良的慢性肠炎。
萸肉：其性平、味甘、酸，功能养肝肾，敛阴止汗救脱，为滋补肾阴要药，主要用于肝肾阴虚证，适用于肝肾两虚所致的腰膝酸软，眩晕耳鸣，阳痿、遗精，小便频数，虚汗不止等症。
泽泻：甘，寒。功效：利水，渗湿，泄热。治小便不利，水肿胀满，呕吐，泻痢，痰饮，脚气，淋病，尿血
玄参：主治：温热病和营血、身热、烦渴、舌绛、发斑、骨蒸劳嗽、虚烦不寤、津伤便秘、目涩昏花、咽喉肿痛、瘰疬痰核、痈疽疮毒。
丹皮：辛苦；凉；微寒。清热；活血散瘀。主温热病热入血分；发斑；吐衄；热泪盈眶病菌后期热伏阴分发热；阴虚骨蒸潮热；血滞经闭；痛经；痈肿疮毒；跌扑伤痛；风湿热痹。
茵陈：茵陈清热利湿；退黄。主治：黄疸、小便不利、湿疮瘙痒、传染性黄疸型肝炎等。药理学研究有利胆，保护肝功能，解热，抗炎，降血脂，降压，扩冠等作用。
炒山栀：治热病虚烦不眠，黄疸，淋病，消渴，目赤，咽痛，吐血，衄血，血痢，尿血，热毒疮疡，扭伤肿痛。
黄连：苦，寒。归心、脾、胃、肝、胆、大肠经。清热燥湿，泻火解毒。用于湿热痞满，呕吐吞酸，泻痢，黄疸，高热神昏，心火亢盛，心烦不寐，血热吐衄，目赤，牙痛，消渴。
半夏：具有燥湿化痰，降逆止呕，生用消疖肿作用，兽医用以治锁喉癀。
沙参：甘而微苦，有滋补、祛寒热、清肺止咳，也有治疗心脾痛、头痛、妇女白带之效。主治气管炎，百日咳，肺热咳嗽，咯痰黄稠。根煮去苦味后，可食用。
寸冬：具有养阴生津，润肺止咳：用于肺胃阴虚之津少口渴的功效，寸冬为百合科多年生草本植物。
蒲公英：甘，微苦，寒。清热解毒，消肿散结。清热解毒，利尿散结。治急性乳腺炎，淋巴腺炎，瘰疬，疔毒疮肿，急性结膜炎，感冒发热，急性扁桃体炎，急性支气管炎，胃炎，肝炎，胆囊炎，尿路感染。
枇杷叶：苦，凉。清肺气，降肺火，止咳化痰，止吐血呛血，治痈痿热毒。
连翘：性味苦，微寒。清热解毒的中药，主治热病初起，风热感冒，发热，心烦，咽喉肿痛，斑疹，丹毒，瘰疬，痈疮肿毒，急性肾炎，热淋。
射干：用于感受风热，或痰热壅盛所致的咽喉肿痛等症。用于痰涎壅盛，咳嗽气喘等症。咽喉肿痛，喉痹不通，二便不通，诸药不效，腹部积水，皮肤发黑，乳痈初起。
神曲：健脾和胃，消食化积。用于饮食停滞，消化不良，脘腹胀满，食欲不振，呕吐泻痢。
炒麦芽：主治食积不消，脘腹胀痛，脾虚食少，乳汗郁积，乳房胀痛，妇女断乳。
磁石：镇惊安神，平肝潜阳，聪耳明目，纳气平喘。用于惊悸失眠，头晕目眩，视物昏花，耳鸣耳聋，肾虚气喘。
甘草：功能主治清热解毒、祛痰止咳、脘腹等。
本发明以生熟地、山药、萸肉、泽泻、玄参为君药，以丹皮、茵陈、炒山栀、黄连、半夏为臣药，以沙参、寸冬、蒲公英、连翘、射干、甘草等为辅佐药。
与现有技术相比，本发明具有以下有益效果：
1本发明所使用的中草药均符合《中华人名共和国药典》规定，根据配伍，本发明具有清热凉血、咽喉肿痛、泻火解毒、养阴生津、消肿散结的作用。
2、本发明辩证准确、配伍合理、用药精良、审因而治、治病求本。
以下为临床试验总结：临床试验治疗口舌生疮患者100例。口舌生疮的症状，临床上常见有：本病的主要症状是口腔黏膜反复出现圆形或椭圆形小溃疡，可单发或多发在口腔黏膜的任何部分，有剧烈的自发痛，一般在10天左右可自愈。局部症状比较显著，全身症状多不明显。愈合不留任何瘢痕，但可以反复发作。好发于青壮年，女性多于男性。发病时唇、颏、舌边缘、牙龈等处出现孤立的圆形成椭圆形成浅层小溃疡，有的同时多处发生。疼痛剧烈似烧灼样。随天气、情绪、劳累等因素可复发。多由心脾积热，外感热邪，或脾胃湿热，阴虚阳亢所致。
治疗方案：服用实施水煎口服，每日二剂，60天为一疗程。
治疗结果：口舌生疮患者经过一个疗程治疗后痊愈80例，占80%，好转20例，占20%，无效0例，总有效率85%。通过治疗所示，对病人无任何副作用。
治疗标准：
口舌生疮症状消失。
无效症状及体征无明显改善。
具体实施方式
下面结合实施例对本发明做进一步的说明。
实施例
中药原料的重量组成为：生熟地15克、山药30克、萸肉10克、泽泻15克、玄参20克、丹皮12克、茵陈30克、炒山栀12克、黄连12克、半夏12克、沙参20克、寸冬15克、蒲公英30克、枇杷叶20克、连翘20克、射干15克、神曲30克、炒麦芽30克、磁石15克、甘草6克。
病例1：患者李某某，女，66岁，因口舌生疮、发热，心烦于2014年4月在当地医院诊为口舌生疮症状，口服药物治疗月余无效，于2014年9月来诊我院，给予本发明药物治疗一个疗程后症状全部消失，随访一年未复发。
病例2：患者沈某某，女，58岁，因口舌生疮、疼痛剧烈被诊为口舌生疮症，服用本发明药物治疗一个疗程后症状、体征全部消失。随访一年未复发。
病例3：患者张某某，男69岁，2016年4月份因身热、烦渴、舌绛，口舌生疮经检查确诊为口舌生疮症，服用本发明药物治疗一个疗程后症状全部消失，随访一年未复发。

Claims (1)

1.一种治疗口舌生疮的中药制剂，其特征在于各中药原料的重量组成为：生熟地15克、山药30克、萸肉10克、泽泻15克、玄参20克、丹皮12克、茵陈30克、炒山栀12克、黄连12克、半夏12克、沙参20克、寸冬15克、蒲公英30克、枇杷叶20克、连翘20克、射干15克、神曲30克、炒麦芽30克、磁石15克、甘草6克。
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN109364138A (zh) * 2018-12-12 2019-02-22 马建国 一种治疗念珠菌性口角炎的药油及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109364138A (zh) * 2018-12-12 2019-02-22 马建国 一种治疗念珠菌性口角炎的药油及其制备方法

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