CN108697782A - 针对pcv2病毒和猪肺炎支原体感染的组合疫苗 - Google Patents

针对pcv2病毒和猪肺炎支原体感染的组合疫苗 Download PDF

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Publication number
CN108697782A
CN108697782A CN201780014561.9A CN201780014561A CN108697782A CN 108697782 A CN108697782 A CN 108697782A CN 201780014561 A CN201780014561 A CN 201780014561A CN 108697782 A CN108697782 A CN 108697782A
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CN
China
Prior art keywords
vaccine
pcv2
immunogene
mycoplasma hyopneumoniae
replicating
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Pending
Application number
CN201780014561.9A
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English (en)
Chinese (zh)
Inventor
M.斯诺
M.H.维特弗利耶
V.法辛格尔
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Intervet International BV
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Intervet International BV
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Publication of CN108697782A publication Critical patent/CN108697782A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/105Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CN201780014561.9A 2016-03-23 2017-03-22 针对pcv2病毒和猪肺炎支原体感染的组合疫苗 Pending CN108697782A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16161997.8 2016-03-23
EP16161997 2016-03-23
PCT/EP2017/056831 WO2017162741A1 (en) 2016-03-23 2017-03-22 A combination vaccine against pcv2 virus and mycoplasma hyopneumoniae infection

Publications (1)

Publication Number Publication Date
CN108697782A true CN108697782A (zh) 2018-10-23

Family

ID=55589754

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780014561.9A Pending CN108697782A (zh) 2016-03-23 2017-03-22 针对pcv2病毒和猪肺炎支原体感染的组合疫苗

Country Status (7)

Country Link
US (1) US20190105385A1 (enExample)
EP (1) EP3432919A1 (enExample)
JP (1) JP6907227B2 (enExample)
CN (1) CN108697782A (enExample)
BR (1) BR112018069100A2 (enExample)
RU (1) RU2018137034A (enExample)
WO (1) WO2017162741A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114364398A (zh) * 2019-09-12 2022-04-15 英特维特国际股份有限公司 用于皮内施用的联合疫苗

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020011044A2 (pt) * 2017-12-04 2020-11-17 Intervet International B.V. vacinação com partículas de replicon e adjuvante de óleo
JP7510874B2 (ja) * 2017-12-22 2024-07-04 ヒプラ シエンティフィック エセ.エレ.ウ. マイコプラズマ及びブタサーコウイルスに対する皮内混合ワクチン
EP4138892A1 (en) * 2020-04-20 2023-03-01 Intervet International B.V. A vaccine to protect against mycoplasma hyopneumoniae
CN115427072A (zh) * 2020-04-20 2022-12-02 英特维特国际股份有限公司 预防性治疗猪的疫苗组合
WO2025132513A1 (en) 2023-12-19 2025-06-26 Intervet International B.V. Low-energy electron irradiation-inactivated mollicutes

Citations (7)

* Cited by examiner, † Cited by third party
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US20050220814A1 (en) * 2004-04-05 2005-10-06 Dominowski Paul J Microfluidized oil-in-water emulsions and vaccine compositions
WO2007006939A2 (fr) * 2005-07-07 2007-01-18 Sanofi Pasteur Emulsion immuno-adjuvante thermoreversible
CN102006884A (zh) * 2008-04-18 2011-04-06 英特威国际有限公司 防御胞内劳森菌、猪肺炎支原体和猪圆环病毒的疫苗
CN103263666A (zh) * 2013-05-24 2013-08-28 北京大北农科技集团股份有限公司动物医学研究中心 猪圆环病毒2型、猪支原体肺炎二联灭活疫苗及其制备方法
CN104043118A (zh) * 2013-03-11 2014-09-17 普莱柯生物工程股份有限公司 猪prrsv、猪肺炎支原体和pvc-2抗原在制备疫苗中的应用
CN104271153A (zh) * 2012-04-04 2015-01-07 硕腾有限责任公司 Pcv/猪肺炎支原体/prrs组合疫苗
CN104334186A (zh) * 2012-04-04 2015-02-04 硕腾有限责任公司 Pcv/猪肺炎支原体组合疫苗

Family Cites Families (11)

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HU212924B (en) * 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
JP2006528647A (ja) * 2003-07-24 2006-12-21 メリアル リミテッド 新規ワクチン製剤
ATE462445T1 (de) 2005-01-13 2010-04-15 Boehringer Ingelheim Vetmed Prrs-impfstoffe
US8834891B2 (en) * 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
DK1926496T3 (da) 2005-09-09 2013-09-30 Intervet Int Bv PCV-2-vaccine
DK2371383T3 (en) 2005-12-29 2015-11-30 Boehringer Ingelheim Vetmed Use of a PCV2 immunogenic composition for reduction of clinical symptoms in pigs
AU2007333857B2 (en) 2006-12-15 2014-05-15 Boehringer Ingelheim Animal Health USA Inc. Treatment of pigs with PCV2 antigen
US8728487B2 (en) 2011-01-20 2014-05-20 Hua Wu Attenuated live vaccine for prevention of porcine reproductive and respiratory syndrome
CA2848163C (en) * 2011-09-09 2020-10-27 Nanobio Corporation Nanoemulsion respiratory syncytial virus (rsv) subunit vaccine
US9457073B2 (en) 2012-09-26 2016-10-04 University Of Manitoba Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity
WO2015082457A1 (en) * 2013-12-03 2015-06-11 Intervet International B.V. Vaccine against lawsonia intracellularis and porcine circovirus 2

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220814A1 (en) * 2004-04-05 2005-10-06 Dominowski Paul J Microfluidized oil-in-water emulsions and vaccine compositions
CN1997390A (zh) * 2004-04-05 2007-07-11 辉瑞产品有限公司 微流化水包油乳状液和疫苗组合物
WO2007006939A2 (fr) * 2005-07-07 2007-01-18 Sanofi Pasteur Emulsion immuno-adjuvante thermoreversible
CN102006884A (zh) * 2008-04-18 2011-04-06 英特威国际有限公司 防御胞内劳森菌、猪肺炎支原体和猪圆环病毒的疫苗
CN104271153A (zh) * 2012-04-04 2015-01-07 硕腾有限责任公司 Pcv/猪肺炎支原体/prrs组合疫苗
CN104334186A (zh) * 2012-04-04 2015-02-04 硕腾有限责任公司 Pcv/猪肺炎支原体组合疫苗
JP2015512450A (ja) * 2012-04-04 2015-04-27 ゾエティス・エルエルシー Pcv/マイコプラズマ・ハイオニューモニエ/prrs混合ワクチン
CN104043118A (zh) * 2013-03-11 2014-09-17 普莱柯生物工程股份有限公司 猪prrsv、猪肺炎支原体和pvc-2抗原在制备疫苗中的应用
CN103263666A (zh) * 2013-05-24 2013-08-28 北京大北农科技集团股份有限公司动物医学研究中心 猪圆环病毒2型、猪支原体肺炎二联灭活疫苗及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114364398A (zh) * 2019-09-12 2022-04-15 英特维特国际股份有限公司 用于皮内施用的联合疫苗

Also Published As

Publication number Publication date
JP2019509300A (ja) 2019-04-04
BR112018069100A2 (pt) 2019-01-29
WO2017162741A1 (en) 2017-09-28
JP6907227B2 (ja) 2021-07-21
RU2018137034A (ru) 2020-04-23
EP3432919A1 (en) 2019-01-30
RU2018137034A3 (enExample) 2020-06-26
US20190105385A1 (en) 2019-04-11

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