CN108669266A - A kind of Guava Leaf health protection tea and preparation method thereof - Google Patents

A kind of Guava Leaf health protection tea and preparation method thereof Download PDF

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Publication number
CN108669266A
CN108669266A CN201810415278.3A CN201810415278A CN108669266A CN 108669266 A CN108669266 A CN 108669266A CN 201810415278 A CN201810415278 A CN 201810415278A CN 108669266 A CN108669266 A CN 108669266A
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China
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parts
guava leaf
preparation
leaf
oligofructose
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CN201810415278.3A
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Inventor
李交昆
周智广
曾伟民
胡芳
申丽
谢志国
余润兰
吴学玲
刘元东
吴晨晨
李芳�
刘阿娟
邱冠周
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Central South University
Second Xiangya Hospital of Central South University
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Central South University
Second Xiangya Hospital of Central South University
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00—Tea; Tea substitutes; Preparations thereof
    • A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

The invention discloses a kind of Guava Leaf health protection tea, raw material includes each component of following mass fraction：15 30 parts of 10 25 parts of Guava Leaf, 15 parts of fresh ginger slice, 0.5 2 parts of duck wheat, 5 20 parts of the root bark of Chinese wolf-berry, 14 parts of pueraria lobata, 28 parts of mulberry leaf, 14 parts of dried orange peel, 5 15 parts of matrimony vine, 39 parts of Radix Salviae Miltiorrhizae, 13 parts of rhizoma anemarrhenae, 4 10 parts of Radix Angelicae Sinensis and oligofructose.The product can guarantee hypoglycemic effect and taste while cost reduction.The invention also discloses preparation methods, include the following steps：It weighs mulberry leaf, dried orange peel, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae and Guava Leaf to dry, grinds to obtain powder sieving, be ultrasonically treated after pure water is added, 35 DEG C are refrigerated to hereinafter, progress vacuum freeze drying, obtains pulverulent solids after filtering off filter residue；Radix Angelicae Sinensis, fresh ginger slice, duck wheat, pueraria lobata and matrimony vine chopping are weighed, is uniformly sprayed into after oligofructose is dissolved with pure water wherein, tea bag is distributed into pulverulent solids after drying.The preparation method, easy to operate, low manufacture cost produce convenient for large-scale processing.

Description

A kind of Guava Leaf health protection tea and preparation method thereof
Technical field
The invention belongs to field of health-care tea more particularly to a kind of Guava Leaf health protection tea and preparation method thereof.
Background technology
7th edition diabetes map denotation of International Diabetes Federation (IDF) publication just has one every 6 seconds in the whole world A diabetic is dead, and the death rate of diabetes is more than AIDS, the summation of malaria, the tuberculosis death rate.In 2015, China Adult (20~79 years old) diabetic up to 1.096 hundred million, occupy various countries first place, diabetes, which have become Medical, urgently to be solved Certainly the problem of.At present when treating diabetes, the country tends to the preferable sulfonylurea drugs of using effect, biguanides etc. Oral western medicine, however these drug side-effects are very big, and be not suitable for taking for a long time.For this purpose, finding drop that is natural, having no toxic side effect Sugar substance becomes particularly significant.
Civil in China and Japan, useful coarse tea leaf comes hypoglycemic people very early, allows public income, but effect is all It is not satisfactory.Main cause, which is high temperature, can destroy tea polysaccharide, and thick tea contains higher Tea Polysaccharides, it is to inhibit blood glucose rise Best natural drug.So the civil common boiling water method of making tea cannot function well as hypoglycemic effect.
Invention content
The technical problem to be solved by the present invention is to overcome the shortcomings of to mention in background above technology and defect, provide one Kind of Guava Leaf health protection tea and preparation method thereof, by Guava Leaf, fresh ginger slice, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, mulberry leaf, dried orange peel, Matrimony vine, oligofructose are merged, and the effect of it prevents with synergistic treatment hyperglycemic disorder is enhanced.The present invention by Guava Leaf with Other Chinese medicine compatibilities, can be hypoglycemic and adjust metabolic function, lowering blood pressure and blood fat, are a kind of multi-functional health cares Product.
In order to solve the above technical problems, technical solution proposed by the present invention is to provide a kind of Guava Leaf health protection tea, raw material Include each component of following mass fraction：10-25 parts of Guava Leaf, 1-5 parts of fresh ginger slice, 0.5-2 parts of duck wheat, root bark of Chinese wolf-berry 5-20 Part, 1-4 part of pueraria lobata, 2-8 parts of mulberry leaf, 1-4 parts of dried orange peel, 5-15 parts of matrimony vine, 3-9 parts of Radix Salviae Miltiorrhizae, 1-3 parts of rhizoma anemarrhenae, 4-10 parts of Radix Angelicae Sinensis with 15-30 parts of oligofructose.
Main sugar reducing substance is general flavone in Guava Leaf, and main component is rutin, morin, Quercetin and kaempferia galamga Phenol.Unique activity composition --- the bitter buckwheat flavone of duck wheat, main ingredient have Quercetin, rutin, bank phenanthrene alcohol, morin.The two Existing identical component, also there is heterogeneity, can learn from other's strong points to offset one's weaknesses, and further increases hypoglycemic effect.
Fresh ginger slice has the appetitive effect of Appetizing spleen-tonifying, and cold extermination clearing damp can be played by being used in conjunction with Guava Leaf, be carried The effect that god is recovered from fatigue；Mulberry leaf have dispelling wind and heat from the body, clearing away the lungheat and moisturizing the effect of clearing liver and improving vision, with Guava Leaf compatibility, to there is clearing lung-heat profit Dry, cough-relieving reduces phlegm and internal heat, resolving sputum, controls night sweat and other effects；Matrimony vine can tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity, blood-enriching tranquillizing promotes the production of body fluid to quench thirst, moistening lung Cough-relieving can control soreness and weakness of waist and knees with Guava Leaf compatibility, and dizzy, dizzy, the more tears of blurred vision, cough due to consumptive disease is quenched one's thirst.Fresh ginger slice, mulberry Leaf, matrimony vine, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, dried orange peel and Guava Leaf are used in conjunction with, and can play inducing diaphoresis of bringing down a fever, quench one's thirst of promoting the production of body fluid, The unexpected effect of Shengyang Zhixie these types.Above-mentioned mulberry leaf, Guava Leaf are all made of the fresh leaf of picking, using fresh feed energy Keep the former ingredient and effect for growing original flavor of raw material itself.
Oligofructose is non-digestible sugar, cannot be converted to monosaccharide (glucose) and be absorbed by the body, therefore will not cause blood glucose Level fluctuation and insulin change, and in the case where oligofructose helps probiotics to have the advantage, probiotics can largely absorb simultaneously Monosaccharide is eaten up, the monosaccharide for being rapidly absorbed into blood is reduced, improves glycometabolism.Therefore, hyperglycemia population and diabetes patient can put The heart is edible.Oligofructose can also be obviously improved microbial population ratio in enteron aisle, it be enteral Bifidobacterium activation and proliferation because Son can reduce and inhibit the generation of enteral corrupt substance, inhibit the growth of harmful bacteria, adjust enteron aisle inner equilibrium；It can promote micro- The absorption and utilization of secondary element iron, calcium, to prevent osteoporosis；Hepatotoxin can be reduced, having for anticancer can be generated in intestines Machine acid, there is significant preventing cancer function.Meanwhile the addition of oligofructose helps to improve mouthfeel, makes consumer be easier to receive, has Conducive to sale, and blood glucose rise will not be made, be consistent with the original intention of the present invention.
Guava Leaf：Mild-natured, sweet-puckery flavor enters spleen, stomach, large intestine, Liver Channel, modern pharmacological studies have shown that its contain it is hypoglycemic, Antiviral and antibacterial isoreactivity substance.Have studies have shown that rich in Huangs such as sitosterol, triterpenes and Quercetins in Guava Leaf Ketone compounds, and many flavone compounds have inhibition alpha-glucosaccharase enzyme effect.Active ingredient in Guava Leaf is yellow Ketoside has and promotes insulin that can adjust glycometabolism, lipid metaboli with the combination of single-minded receptor on target cell membrane, there is hypoglycemic work With, and have certain decompression, effect for reducing fat.
Duck wheat：Rich in bioflavonoid, multivitamin, 18 kinds of amino acid, crude protein, chlorophyll and its selenium, zinc, The minerals such as magnesium, chromium, calcium and trace element, can auxiliary treatment diabetes, be the optimal selection of diabetic's staple food grain, prevent and Cardiovascular and cerebrovascular disease is treated, it is effective to artery sclerosis, coronary heart disease, myocardial infarction, cerebral infarction, cerebral hemorrhage, apoplexy.
The root bark of Chinese wolf-berry：It is the root skin of matrimony vine, can be used as medicine there is the benefits of bringing down a fever except steaming, cool blood is except steaming, clearing lung-heat fall fire and other effects.
Pueraria lobata：It is sweet in flavor, pungent, it is cool in nature, there is expelling pathogenic factors from muscles and skin to bring down a fever, promoting eruption promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie.It is extracted in pueraria lobata Flavones can increase brain and coronal vascular flow, and vascular resistence reduces, and has hypotensive activity.Puerarin can make alloxan sugared The sick mouse blood glucose of urine is decreased obviously, and blood sugar reducing function is lasting.
Dried orange peel：With ingredients such as hesperidine, tangerine peel pectin, there is expansion coronary artery, reducing blood lipid, prevent artery sclerosis, is notable Mitigate liver cell fatty degeneration degree and other effects, good booster action is provided to be hypoglycemic.
Oligofructose：As sweetener, it cannot directly be digested and assimilated, can only be absorbed and utilized by enteric bacteria by human body, Therefore its calorific value is low, will not lead to obesity, also has antiobesity action indirectly, equally also provides good booster action to be hypoglycemic.
Above-mentioned Guava Leaf health protection tea, it is preferred that raw material includes each component of following mass fraction：Guava Leaf 20- 25 parts, 1-2 parts of fresh ginger slice, 0.5-1 parts of duck wheat, 5-10 parts of the root bark of Chinese wolf-berry, 1-2 parts of pueraria lobata, 6-8 parts of mulberry leaf, 2-4 parts of dried orange peel, Chinese holly 15-20 parts of 5-10 parts of Qi, 3-5 parts of Radix Salviae Miltiorrhizae, 1-2 parts of rhizoma anemarrhenae, 4-7 parts of Radix Angelicae Sinensis and oligofructose.
Preferably, the thickness of the fresh ginger slice is 2-5mm.
Based on a total inventive concept, the present invention also provides a kind of preparation methods of Guava Leaf health protection tea, including such as Lower step：
(1) weigh Guava Leaf, fresh ginger slice, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, mulberry leaf, dried orange peel, matrimony vine, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae, when Return and oligofructose, it is spare；
(2) mulberry leaf, dried orange peel, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae and Guava Leaf that the step (1) weighs are dried, is cut It is ground with pulverizer to obtain powder after broken, be sieved, is ultrasonically treated after pure water is added, obtained ultrasonic extraction liquid filters off filter residue After be refrigerated to -35 DEG C hereinafter, then carry out vacuum freeze drying, until when temperature of charge curve is with temperature of heating plate oriented parallel Terminate, obtains pulverulent solids；The process for being refrigerated to -35 DEG C is pre-freeze, it is therefore an objective to so that material is freezed rapidly, pre-freeze junction temperature is answered It is excessively high to freeze rapidly less than eutectic point, too low increase energy consumption；
(3) Radix Angelicae Sinensis, fresh ginger slice, duck wheat, pueraria lobata and matrimony vine that the step (1) weighs are shredded and is mixed Object uniformly sprays into mixture after dissolving oligofructose with pure water, it is dry after with the pulverulent solids obtained by the step (2) Tea bag is distributed into get to Guava Leaf health protection tea.
Above-mentioned preparation method, it is preferred that in the step (2), be sieved for 40 mesh sieve.
Preferably, in the step (2), the addition of pure water is 35-45 times of powder quality.
Preferably, in the step (2), the power of supersound process is 300-500W, time 25-45min, and temperature is 60-70℃。
Preferably, in the step (2), at least 2h is freezed in cooling time 8-12h, holding.
Preferably, in the step (2), temperature of heating plate used by vacuum freeze drying is 45-55 DEG C, and vacuum degree is 35-45Pa.It is 45-55 DEG C to initially set up temperature of heating plate, and temperature can make moisture maximum volatilize close to the eutectic point of material, If higher than the eutectic point of material, material will be made to thaw.
Preferably, in the step (3), the addition of pure water is 10-15 times of oligofructose quality.
Compared with prior art, beneficial effects of the present invention are：
1, Guava Leaf health protection tea of the invention, using Guava Leaf as main material, using the duck wheat of few deal, simultaneously It is equipped with other and is conducive to hypoglycemic and health care composition so that product of the present invention can guarantee drop blood while cost reduction Effect and taste of sugar, and be convenient for carrying；Fresh ginger slice, matrimony vine, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, dried orange peel, Radix Salviae Miltiorrhizae, is known mulberry leaf Female, Radix Angelicae Sinensis and Guava Leaf compatible use, hypoglycemic effect uses Guava Leaf better than simple, and can play inducing diaphoresis of bringing down a fever, raw Tianjin is quenched one's thirst, the unexpected effect of Shengyang Zhixie these types.
2, preparation method of the invention, easy to operate, low manufacture cost produce convenient for large-scale processing.
Specific implementation mode
To facilitate the understanding of the present invention, the present invention is done below in conjunction with preferred embodiment and more comprehensively, is meticulously described, But protection scope of the present invention is not limited to following specific examples.
Unless otherwise defined, all technical terms used hereinafter are generally understood meaning phase with those skilled in the art Together.Technical term used herein is intended merely to the purpose of description specific embodiment, is not intended to the limitation present invention's Protection domain.
Unless otherwise specified, various raw material, reagent, the instrument and equipment etc. used in the present invention can pass through city Field is commercially available or can be prepared by existing method.
Embodiment 1：
A kind of Guava Leaf health protection tea of the present invention, includes each component of following mass fraction：20 parts of Guava Leaf, yellow ginger 1 part of piece, 0.5 part of duck wheat, 5 parts of the root bark of Chinese wolf-berry, 1 part of pueraria lobata, 8 parts of mulberry leaf, 4 parts of dried orange peel, 10 parts of matrimony vine, 3 parts of Radix Salviae Miltiorrhizae, 1 part of rhizoma anemarrhenae, The thickness of 20 parts of 4 parts of Radix Angelicae Sinensis and oligofructose, the fresh ginger slice is 5mm.
The preparation method of above-mentioned Guava Leaf health protection tea, includes the following steps：
(1) weigh Guava Leaf, fresh ginger slice, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, mulberry leaf, dried orange peel, matrimony vine, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae, when Return and oligofructose, it is spare；
(2) mulberry leaf, dried orange peel, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae and Guava Leaf that the step (1) weighs are dried, is cut It grinds to obtain powder with pulverizer after broken, crosses 40 mesh sieve, be ultrasonically treated after the pure water of 40 times of powder quality is added, at ultrasound The power of reason is 300W, and time 25min, temperature is 60 DEG C, and obtained ultrasonic extraction liquid is freezed after filtering off filter residue with the 8h times It to -35 DEG C, and keeps freezing at least 2h, then carries out vacuum freeze drying, until temperature of charge curve is bent with temperature of heating plate Terminate when line is parallel, temperature of heating plate used by vacuum freeze drying is 45 DEG C, vacuum degree 40Pa, is obtained powdered solid Body；
(3) Radix Angelicae Sinensis, fresh ginger slice, duck wheat, pueraria lobata and matrimony vine that the step (1) weighs are shredded and is mixed Object, will oligofructose dissolved with 13 times of quality pure water after uniformly spray into mixture, it is dry after with the powder obtained by the step (2) Last shape solid is distributed into tea bag to get to Guava Leaf health protection tea.
To evaluate the hypoglycemic effect of micron Guava Leaf Jiangtang capsule that the present embodiment obtains to diabetes B, use Db/db diabetic mices give gavage daily as experimental subjects, with Guava Leaf health protection tea to mouse, totally 4 weeks, measure weekly The situation of change of each group fasting blood-glucose.The results show that compared with blood glucose (22.0mol/L) when gavage 2 weeks, 4 Zhou Hou little of gavage Mouse blood glucose is decreased obviously (17.0mol/L).
Embodiment 2：
A kind of Guava Leaf health protection tea of the present invention, includes each component of following mass fraction：25 parts of Guava Leaf, yellow ginger 2 parts of piece, 1 part of duck wheat, 10 parts of the root bark of Chinese wolf-berry, 2 parts of pueraria lobata, 6 parts of mulberry leaf, 2 parts of dried orange peel, 5 parts of matrimony vine, 9 parts of Radix Salviae Miltiorrhizae, 3 parts of rhizoma anemarrhenae, when Return 10 parts and 15 parts of oligofructose, the thickness of the fresh ginger slice is 2mm.
The preparation method of above-mentioned Guava Leaf health protection tea, includes the following steps：
(1) weigh Guava Leaf, fresh ginger slice, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, mulberry leaf, dried orange peel, matrimony vine, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae, when Return and oligofructose, it is spare；
(2) mulberry leaf, dried orange peel, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae and Guava Leaf that the step (1) weighs are dried, is cut It grinds to obtain powder with pulverizer after broken, crosses 40 mesh sieve, be ultrasonically treated after the pure water of 40 times of powder quality is added, at ultrasound The power of reason is 500W, and time 45min, temperature is 70 DEG C, and obtained ultrasonic extraction liquid is freezed after filtering off filter residue with the 12h times It to -35 DEG C, and keeps freezing at least 2h, then carries out vacuum freeze drying, until temperature of charge curve is bent with temperature of heating plate Terminate when line is parallel, temperature of heating plate used by vacuum freeze drying is 55 DEG C, vacuum degree 35Pa, is obtained powdered solid Body；
(3) Radix Angelicae Sinensis, fresh ginger slice, duck wheat, pueraria lobata and matrimony vine that the step (1) weighs are shredded and is mixed Object, will oligofructose dissolved with 10 times of quality pure water after uniformly spray into mixture, it is dry after with the powder obtained by the step (2) Last shape solid is distributed into tea bag to get to Guava Leaf health protection tea.
To evaluate the hypoglycemic effect of micron Guava Leaf Jiangtang capsule that the present embodiment obtains to diabetes B, use Db/db diabetic mices give gavage daily as experimental subjects, with Guava Leaf health protection tea to mouse, totally 4 weeks, measure weekly The situation of change of each group fasting blood-glucose.The results show that compared with blood glucose (20.0mol/L) when gavage 2 weeks, 4 Zhou Hou little of gavage Mouse blood glucose is decreased obviously (16.0mol/L).
Embodiment 3：
A kind of Guava Leaf health protection tea of the present invention, includes each component of following mass fraction：20 parts of Guava Leaf, yellow ginger 1 part of piece, 1 part of duck wheat, 5 parts of the root bark of Chinese wolf-berry, 2 parts of pueraria lobata, 6 parts of mulberry leaf, 2 parts of dried orange peel, 5 parts of matrimony vine, 5 parts of Radix Salviae Miltiorrhizae, 2 parts of rhizoma anemarrhenae, when Return 7 parts and 15 parts of oligofructose, the thickness of the fresh ginger slice is 2mm.
The preparation method of above-mentioned Guava Leaf health protection tea, includes the following steps：
(1) weigh Guava Leaf, fresh ginger slice, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, mulberry leaf, dried orange peel, matrimony vine, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae, when Return and oligofructose, it is spare；
(2) mulberry leaf, dried orange peel, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae and Guava Leaf that the step (1) weighs are dried, is cut It grinds to obtain powder with pulverizer after broken, crosses 40 mesh sieve, be ultrasonically treated after the pure water of 40 times of powder quality is added, at ultrasound The power of reason is 450W, and time 40min, temperature is 65 DEG C, and obtained ultrasonic extraction liquid is freezed after filtering off filter residue with the 9h times It to -35 DEG C, and keeps freezing at least 2h, then carries out vacuum freeze drying, until temperature of charge curve is bent with temperature of heating plate Terminate when line is parallel, temperature of heating plate used by vacuum freeze drying is 50 DEG C, vacuum degree 45Pa, is obtained powdered solid Body；
(3) Radix Angelicae Sinensis, fresh ginger slice, duck wheat, pueraria lobata and matrimony vine that the step (1) weighs are shredded and is mixed Object, will oligofructose dissolved with 15 times of quality pure water after uniformly spray into mixture, it is dry after with the powder obtained by the step (2) Last shape solid is distributed into tea bag to get to Guava Leaf health protection tea.
To evaluate the hypoglycemic effect of micron Guava Leaf Jiangtang capsule that the present embodiment obtains to diabetes B, use Db/db diabetic mices give gavage daily as experimental subjects, with Guava Leaf health protection tea to mouse, totally 4 weeks, measure weekly The situation of change of each group fasting blood-glucose.The results show that compared with blood glucose (18.0mol/L) when gavage 2 weeks, 4 Zhou Hou little of gavage Mouse blood glucose is decreased obviously (14.0mol/L).
Comparative example：
A kind of Guava Leaf health protection tea, includes each component of following mass fraction：20 parts of Guava Leaf, 1 part of fresh ginger slice, ground The thickness of 15 parts of 5 parts of bone skin, 2 parts of pueraria lobata, 2 parts of dried orange peel, 5 parts of matrimony vine and oligofructose, the fresh ginger slice is 2mm.
The preparation method of above-mentioned Guava Leaf health protection tea, includes the following steps：
(1) Guava Leaf, fresh ginger slice, the root bark of Chinese wolf-berry, pueraria lobata, dried orange peel, matrimony vine and oligofructose are weighed, it is spare；
(2) dried orange peel, the root bark of Chinese wolf-berry and Guava Leaf that the step (1) weighs are dried, is ground with pulverizer after chopping It is broken to obtain powder, 40 mesh sieve is crossed, is ultrasonically treated after the pure water of 40 times of powder quality is added, the power of supersound process is 450W, time 40min, temperature are 65 DEG C, and obtained ultrasonic extraction liquid filters off and is refrigerated to -35 DEG C with the 9h times after filter residue, and At least 2h is freezed in holding, then carries out vacuum freeze drying, is tied when until temperature of charge curve is with temperature of heating plate oriented parallel Beam, temperature of heating plate used by vacuum freeze drying are 50 DEG C, obtain pulverulent solids；
(3) it shreds fresh ginger slice, pueraria lobata and matrimony vine that the step (1) weighs to obtain mixture, by oligofructose It uniformly sprays into mixture after being dissolved with 15 times of quality pure water, is dispensed with the pulverulent solids obtained by the step (2) after dry At tea bag to get to Guava Leaf health protection tea.
To evaluate the hypoglycemic effect of micron Guava Leaf Jiangtang capsule that this comparative example obtains to diabetes B, use Db/db diabetic mices give gavage daily as experimental subjects, with Guava Leaf health protection tea to mouse, totally 4 weeks, measure weekly The situation of change of each group fasting blood-glucose.The results show that compared with blood glucose (17.0mol/L) when gavage 2 weeks, 4 Zhou Hou little of gavage Mouse blood glucose is not decreased obviously (16.0mol/L).

Claims (10)

1. a kind of Guava Leaf health protection tea, which is characterized in that raw material includes each component of following mass fraction：Guava Leaf 10- 25 parts, 1-5 parts of fresh ginger slice, 0.5-2 parts of duck wheat, 5-20 parts of the root bark of Chinese wolf-berry, 1-4 parts of pueraria lobata, 2-8 parts of mulberry leaf, 1-4 parts of dried orange peel, Chinese holly 15-30 parts of 5-15 parts of Qi, 3-9 parts of Radix Salviae Miltiorrhizae, 1-3 parts of rhizoma anemarrhenae, 4-10 parts of Radix Angelicae Sinensis and oligofructose.
2. Guava Leaf health protection tea according to claim 1, which is characterized in that raw material includes each group of following mass fraction Point：20-25 parts of Guava Leaf, 1-2 parts of fresh ginger slice, 0.5-1 parts of duck wheat, 5-10 parts of the root bark of Chinese wolf-berry, 1-2 parts of pueraria lobata, mulberry leaf 6-8 15-20 parts of part, 2-4 parts of dried orange peel, 5-10 parts of matrimony vine, 3-5 parts of Radix Salviae Miltiorrhizae, 1-2 parts of rhizoma anemarrhenae, 4-7 parts of Radix Angelicae Sinensis and oligofructose.
3. Guava Leaf health protection tea according to claim 1 or 2, which is characterized in that the thickness of the fresh ginger slice is 2- 5mm。
4. the preparation method of the Guava Leaf health protection tea described in a kind of any one of claim 1-3, includes the following steps：
(1) weigh Guava Leaf, fresh ginger slice, duck wheat, the root bark of Chinese wolf-berry, pueraria lobata, mulberry leaf, dried orange peel, matrimony vine, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae, Radix Angelicae Sinensis and Oligofructose, it is spare；
(2) mulberry leaf, dried orange peel, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, rhizoma anemarrhenae and Guava Leaf that the step (1) weighs are dried, after chopping It is ground to obtain powder with pulverizer, be sieved, is ultrasonically treated after pure water is added, it is cold after obtained ultrasonic extraction liquid elimination filter residue Freeze to -35 DEG C hereinafter, then carry out vacuum freeze drying, obtains pulverulent solids；
(3) it shreds Radix Angelicae Sinensis, fresh ginger slice, duck wheat, pueraria lobata and matrimony vine that the step (1) weighs to obtain mixture, it will Oligofructose uniformly sprays into mixture after being dissolved with pure water, is dispensed with the pulverulent solids obtained by the step (2) after dry At tea bag to get to Guava Leaf health protection tea.
5. preparation method according to claim 4, which is characterized in that in the step (2), be sieved for 40 mesh sieve.
6. preparation method according to claim 4, which is characterized in that in the step (2), the addition of pure water is powder 35-45 times of quality.
7. preparation method according to claim 4, which is characterized in that in the step (2), the power of supersound process is 300-500W, time 25-45min, temperature are 60-70 DEG C.
8. preparation method according to claim 4, which is characterized in that in the step (2), cooling time 8-12h is protected It holds and freezes at least 2h.
9. preparation method according to claim 4, which is characterized in that in the step (2), vacuum freeze drying is used Temperature of heating plate be 45-55 DEG C, vacuum degree 35-45Pa, vacuum freeze drying is until temperature of charge curve and heating plate temperature Terminate when spending oriented parallel.
10. preparation method according to claim 4, which is characterized in that in the step (3), the addition of pure water is low 10-15 times of Fructooligosaccharides quality.
CN201810415278.3A 2018-05-03 2018-05-03 A kind of Guava Leaf health protection tea and preparation method thereof Pending CN108669266A (en)

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Application publication date: 20181019