CN108653634A - 一种用于治疗淤积性皮炎的中药熏洗药剂及其制备方法 - Google Patents
一种用于治疗淤积性皮炎的中药熏洗药剂及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种用于治疗淤积性皮炎的中药熏洗药剂及其制备方法，属中药领域。本发明药物有效成分的原料组成为：小构树叶、剪刀草、牛马藤、黄芪、地瓜藤、丹参、石蝉草、钩藤根、牛抄藤、东风草、芒硝、斑叶兰、老鹳草、木通根、甘草、伸筋草、当归、茉莉花露、白术、楼梯草、小果蕗蕨、三棱、马蹬草、冰片。本发明选用药材的药性相适相辅，针对病因对症下药，有清热利湿、解毒消肿、破血行气、行气活血、化瘀散结、通经活络、舒筋活络、益气补血、祛风止痒、敛疮生肌之功效，吸收效果好，疗效显著，经临床验证对淤积性皮炎治愈率较高。
Description
技术领域
本发明涉及中药领域，尤其涉及一种用于治疗淤积性皮炎的中药熏洗药剂及其制备方法。
背景技术
淤积性皮炎是一种下肢慢性潮红、鳞屑、瘙痒和肿胀（炎症）的皮肤病，常有深褐色皮肤色素沉着，淤积性皮炎常发生在足踝部，最初皮肤出现皮肤瘙痒，红斑，有轻度鳞屑，几周或几个月后皮肤呈深褐色。皮下淤血常被忽视，可能导致水肿加重继发感染，最终引起严重皮肤损害（溃疡形成）。
目前，西医对于本病并无特效疗法，西医通常使用抗组胺类和皮质激素类药物进行治疗，虽能改善局部症状，但不能从根本上消除病因，治标不治本，且长期使用激素类药物，具有诸多不良反应，容易产生耐药性，易反复发作或加重。
中医认为本病主要由于湿热下注，经络阻隔，淤血凝聚，气血不畅；或筋瘤日久，阻塞经络，肌肤失养所致。本发明中药根据病因对症下药，具有清热利湿、解毒消肿、破血行气、行气活血、化瘀散结、通经活络、舒筋活络、益气补血、祛风止痒、敛疮生肌之功效，吸收效果好，疗效显著，经临床验证对淤积性皮炎治愈率较高。
发明内容
本发明提供了一种用于治疗淤积性皮炎的中药熏洗药剂及其制备方法，具有清热利湿、解毒消肿、破血行气、行气活血、化瘀散结、通经活络、舒筋活络、益气补血、祛风止痒、敛疮生肌之功效，治病求源标本兼治，对各种原因引起的淤积性皮炎均具有很好的疗效。
为实现上述目的，本发明的技术方案实施如下：
一种用于治疗淤积性皮炎的中药熏洗药剂，制成所述药物有效成分的原料组成及重量份数为：
小构树叶30～45份、剪刀草30～45份、牛马藤25～40份、黄芪25～40份、
地瓜藤25～35份、丹参15～30份、石蝉草15～30份、钩藤根15～30份、
牛抄藤15～25份、东风草15～25份、芒硝10～20份、斑叶兰10～20份、
老鹳草10～20份、木通根9～15份、甘草9～15份、伸筋草9～15份、
当归9～15份、茉莉花露9～15份、白术9～15份、楼梯草3～12份、
小果蕗蕨3～12份、三棱3～9份、马蹬草1～6份、冰片1～3份。
制成所述药物有效成分的原料组成及重量份数为：
小构树叶35～40份、剪刀草35～40份、牛马藤30～36份、黄芪30～36份、
地瓜藤28～33份、丹参20～25份、石蝉草20～25份、钩藤根20～25份、
牛抄藤18～22份、东风草18～22份、芒硝12～16份、斑叶兰12～16份、
老鹳草12～16份、木通根11～13份、甘草10～12份、伸筋草10～12份、
当归10～12份、茉莉花露10～12份、白术10～12份、楼梯草5～9份、
小果蕗蕨5～9份、三棱4～6份、马蹬草2～4份、冰片1～2份。
制成所述药物有效成分的原料组成及重量份数为：
小构树叶36份、剪刀草36份、牛马藤33份、黄芪33份、
地瓜藤30份、丹参24份、石蝉草23份、钩藤根22份、
牛抄藤20份、东风草20份、芒硝15份、斑叶兰15份、
老鹳草15份、木通根12份、甘草11份、伸筋草10份、
当归10份、茉莉花露10份、白术10份、楼梯草6份、
小果蕗蕨6份、三棱5份、马蹬草3份、冰片1份。
一种用于治疗淤积性皮炎的中药熏洗药剂的制备方法，包括以下工艺步骤：
（1）将小构树叶、剪刀草、地瓜藤、钩藤根、牛抄藤、东风草、当归、白术、楼梯草、小果蕗蕨、三棱、马蹬草洗净后放入容器中，加入8-10倍量的蒸馏水浸泡4-5小时，加热煮沸3-4小时，提取浸液；再次加入6-8倍量的蒸馏水，加热煮沸2-3小时，提取浸液；最后再加入4-6倍量的蒸馏水，加热煮沸 1-2小时，提取浸液；合并三次浸液，过滤，得滤液备用；
（2）将牛马藤、石蝉草、斑叶兰、老鹳草、木通根、伸筋草洗净放入容器内，加入4倍量的浓度80%的乙醇溶液，浸泡1-2小时，加热回流提取3-4小时，过滤，得滤液备用；
（3）将黄芪片加炼熟的蜂蜜与少许开水，拌匀稍闷，放锅内炒至黄色并不粘手时，取出晾凉，粉碎研末，过140目细筛，得细粉，备用；
（4）取丹参片，加黄酒拌匀，闷润至透，置锅内，用文火炒，取出放凉，粉碎研末，过140目细筛，得细粉，备用；
（5）将芒硝粉碎研末，过140目细筛，得细粉，备用；
（6）取净甘草片，加入炼熟的蜂蜜与少许开水，拌匀后稍闷，置炒制容器内，文火炒至深黄色，不粘手时取出，放凉，粉碎研末，过140目细筛，得细粉，备用；
（7）将冰片粉碎研末，过140目细筛，得细粉，备用；
（8）将上述步骤(1)～(7)所制得的滤液和细粉以及茉莉花露混合后，加入8～10倍量的蒸馏水，搅拌溶解均匀后，加热煮沸0.5小时，至60℃以下，静置1小时，过滤，得滤液，将滤液灌装150ml药液袋包装封存，即得所述的中药熏洗药剂。
本发明所用中药的药性如下：
小构树叶：味淡；性凉。清热解毒；祛风止痒；敛疮止血。主治痢疾；神经性皮炎；疥癣；疖肿；刀伤出血。
剪刀草：味苦；辛；性凉。祛风清热；行气活血；解毒消肿。主治感冒发热；食积腹痛；呕吐；泄泻；痢疾；白喉；咽喉肿痛；痈肿丹毒；荨麻疹；毒虫咬伤；跌打伤出血。《湖南药物志》：行气，散血，消积。
牛马藤：味甘，性温。活血化瘀，祛风除湿，通经活络。用于跌打损伤，风湿疼痛、麻木，通经，经闭。《分类草药性》："治寒脾风，风湿麻木，筋骨疼痛，消肿。"
黄芪：味甘；性温。入心；肺；脾；肾经。补气固表；利尿；托毒排脓；生肌敛疮。主治气短心悸；倦怠；乏力；自汗；盗汗；久泻；脱肛；体虚浮肿；子宫脱垂；慢性肾炎；痈疽难溃；或溃久不敛。《新华本草纲要》载：“有补气固表、托毒排脓、生肌的功能。”现代医学研究证实，黄芪具有利尿降压、消炎镇痛、强心、抗氧自由基生成及提高机体免疫功能等多种药理作用，可从多方面作用于机体，改善心血管、脑血管、糖尿病、肾病等相关血管性病变患者的血流动力学和血管内皮细胞等功能。
地瓜藤：味苦；性寒。清热利湿，活血通络，解毒消肿。主治肺热咳嗽；痢疾；水肿；黄疽；小儿消化不良；风湿疼痛；经闭；带下；跌打损伤；痔疮出血；无名肿毒。《四川中药志》：利小便，消湿热黄肿，通月闭，止白带；治痔疮出血及牙龈肿痛。
丹参：味苦；性微寒；无毒。入心；肝经。活血祛瘀，通经止痛，清心除烦，凉血消痈。用于胸痹心痛，脘腹胁痛，瘕瘕积聚，热痹疼痛，心烦不眠，月经不调，痛经经闭，疮疡肿痛。《本经》载：“主心腹邪气，肠鸣幽幽如走水，寒热积聚；破症除瘕，止烦满，益气。”现代医学研究证实，丹参具有消炎止痛、扩张冠状动脉、改善心肌缺血状况、降血压、降血糖、降血脂、保肝、抗菌和促进组织的修复与再生的作用，丹参还具有抗血小板凝聚、降低血液黏度及调节内外凝血系统的功能。
石蝉草：味辛；性凉。归肺；脾；肝；肾经。清热解毒；化瘀散结；利水消肿。主治肺热咳喘；麻疹；疮毒；癌肿；烧烫伤；跌打损伤；肾炎水肿。《云南思茅中草药选》：清热解毒，消肿散瘀，止痛利水。治跌打损伤，烫烧伤，痈肿疮疖，肾炎水肿，肺结核，哮喘，气管支气管炎，肺热咳嗽。
钩藤根：味苦；涩；性寒。入肝经。舒筋活络；清热消肿。主治关节痛风；半身不遂；癫痫；水肿；跌扑损伤。《常用中草药手册》载：“治关节痛风，风湿性关节炎，坐骨神经痛。”现代医学研究表明，钩藤根含吲哚生物碱类，有显著的消炎、抗菌作用。
牛抄藤：味甘；微苦；性寒。归肾；肝；大肠经。舒筋活络；清热利湿；止血。主治风湿麻木；跌打损伤；尿路感染；泌尿系结石；水肿；痢疾；疮痈肿毒；小儿口疮；火眼；癣疾；外伤出血。《广西药植名录》：治痢疾，霍乱抽筋，止血，消炎。
东风草：味苦；微辛；性凉。清热明目；祛风止痒；解毒消肿。主治目赤肿痛；翳膜遮睛；风疹；疥疮；皮肤瘙痒；痈肿疮疖；跌打红肿。
芒硝：味辛；苦；咸；性寒。入胃；肺；脾；肾；小肠；三焦；大肠经。软坚泻下；清热除湿；破血通经；消肿疗疮。主治实热积滞；腹胀便秘；停痰积聚；目赤障翳；丹毒；痈肿。《本经》载：“气坚者以咸软之，热盛者以寒消之，热淫于内，治以咸寒，佐以苦。”临床医学研究表明，芒硝对阑尾及脾脏的网状内皮系统有明显的刺激作用，使其增生现象与吞噬能力有所增强，明显减轻阑尾炎症，能促进小肠、阑尾及袋状结肠运动，调动机体内在的抗病能力，可以加快淋巴生成，有消肿和止痛的作用。
斑叶兰：味甘；辛；性平。润肺止咳；补肾益气；行气活血；消肿解毒。主治肺痨咳嗽；气管炎；头晕乏力；神经衰弱；阳痿；跌打损伤；骨节疼痛；咽喉肿痛；乳痈；疮疖；瘰疬；毒蛇咬伤。《浙江民间常用草药》："清热解毒，消炎退肿。治毒蛇咬伤，痈肿疮疖，肺病咳嗽，气管炎。"
老鹳草：味苦；微辛；性平。归脾；膀胱经。祛风通络；活血；清热利湿。主治风湿痹痛；肌肤麻木；筋骨酸楚；跌打损伤；泄泻痢疾；疮毒。《纲目拾遗》：去风，疏经活血，健筋骨，通络脉。治损伤，痹症，麻木，皮风，浸酒常饮。
木通根：味苦；性平；归肝；肾经。祛风通络；利水消肿；行气活血；补肝肾；强筋骨。主治风湿痹痛；跌打损伤；经闭；疝气；睾丸肿痛；脘腹胀闷；小便不利；带下；虫蛇咬伤。《浙江民间常用草药》：祛风止痛，行气活血，利尿解毒。
甘草：味甘；性平。归心；肺；脾；胃经。补脾益气；清热解毒；祛痰止咳；缓急止痛；调和诸药。主治脾胃虚弱；倦怠乏力；心悸气短；咳嗽痰多；脘腹四肢挛急疼痛；痈肿疮毒；缓解药物毒性。《本草纲目》载：“诸药中甘草为君。治七十二种乳石毒，解一千二百般草本毒，调和从药有功。”现代医学研究证实，甘草有较强的解毒作用，还有抗溃疡、抗炎症、镇痉镇咳、降血压、降血脂、抗癌作用，广泛用于治疗咽喉炎、喉炎、气管炎、支气管炎、哮喘、咳嗽、咳血等疾病，此外还具有抗胃溃疡、抗胃炎作用。
伸筋草：味苦；辛；性温。入肝经。祛风除湿；通经活络；消肿止痛。主治风湿腰腿痛；关节疼痛；跌打损伤；刀伤；烫火伤。《湖南药物志》载：“舒筋活血，补气通络。治腰痛，关节痛，闭经。”现代医学研究表明，伸筋草含有石松碱、棒石松宁碱等生物碱，以及萜类化合物、甾醇和酸类，有降温、降血压作用，能增强心脏收缩力度，兴奋平滑肌，此外还有抑菌作用。
当归：味甘；辛；性温。归肝、心、脾经。补血活血；调经止痛；润肠通便。主治血虚萎黄；眩晕心悸；虚寒腹痛；风湿痹痛；跌扑损伤；痈疽疮疡。《本草正》载：“其味甘而重，故专能补血，其气轻而辛，故又能行血，能养营养血，补气生精，安五脏，强形体，益神志，凡有形虚损之病，无所不宜。”现代医学研究证实，当归具有抗菌、消炎作用，对慢性风湿关节炎急性发作有明显的抑制作用。
茉莉花露：味淡;性温。归脾经。醒脾辟秽;理气;美容泽肌。主治：胸膈陈腐之气；并可润泽肌肤。《中国药植图鉴》：健脾理气。《本草纲目拾遗》：解胸中一切陈腐之气。
白术：味苦；甘；性温。归脾；胃经。健脾益气；燥湿利水；止汗；安胎。主治脾气虚弱；神疲乏力；食少腹胀；大便溏薄；水饮内停；小便不利；水肿；痰饮眩晕；湿痹酸痛；气虚自汗；胎动不安。《本经逢原》载：“术，生用有除湿益燥，消痰利水，治风寒湿痹，死肌痉疸，散腰脐间血，及冲脉为病，逆气里急之功；制熟则有和中补气，止渴生津，止汗除热，进饮食，安胎之效。”现代医学研究证实，白术具有利尿、降血糖、强壮、抗凝血、抗肿瘤、抗菌、促进造血和蛋白质合成的作用。
楼梯草：味微苦；性微寒。归大肠；肝；脾经。清热解毒；祛风除湿；利水消肿；活血止痛。主治赤白痢疾；高热惊风；黄疽；风湿痹痛；水肿；淋证；经闭；疮肿；痄腮；带状疱疹；毒蛇咬伤；跌打损伤；骨折。《新华本草纲要》：全草，味微苦，性平。有清热除湿，活血散瘀功能，用于疾痢、风湿痛、黄疸、水肿、痈疖肿毒、骨折。
小果蕗蕨：味微苦；性凉。清热解毒；敛疮生肌。主治痈疖肿毒；水火烫伤。
三棱：味辛；涩；性凉。入肝；脾经。破血行气；消积止痛。主治症瘕痞块；瘀滞经闭；痛经；食积胀痛；跌打伤痛。《日华子本草》载：“治妇人血脉不调，心腹痛，落胎，消恶血，补劳，通月经，治气胀，消扑损瘀血，产后腹痛、血运并宿血不下。”现代医学研究证实，三棱可加强肠管收缩，对子宫有兴奋作用，能抑制血小板聚集、延长血栓形成时间、消融血栓，降低全血粘度。
马蹬草：味淡；性平。归心经。活血化瘀；止血；解毒。主治血栓闭塞性脉管炎；偏瘫；子宫出血；外伤出血；神经性皮炎；下肢溃疡。
冰片：味辛；苦；性凉。入心；肺经。开窍醒神；散热止痛；明目去翳。主治中风口噤；热病神昏；惊痫痰迷；气闭耳聋；目赤翳膜；喉痹；口疮；痈肿；痔疮；蛲虫病。《本草正》载：“味微甘大辛，敷用者其凉如冰，而气雄力锐。善散气，散血，散火，散滞，通窍，辟恶，逐心腹邪气。”现代医学研究证实，冰片可抑制或杀灭金黄色葡萄球菌、乙型溶菌性链球菌等5种常见细菌，能有效促进其他药物透皮吸收，有利于冠状痉挛的防治，可减轻缺血所致的心肌损伤。
本发明与现有技术相比，具有以下有益效果：
本发明选用药材的药性相适相辅，针对病因对症下药，有清热利湿、解毒消肿、破血行气、行气活血、化瘀散结、通经活络、舒筋活络、益气补血、祛风止痒、敛疮生肌之功效，吸收效果好，疗效显著，经临床验证对淤积性皮炎治愈率较高。
具体实施方式
下面结合具体实施例对本发明做进一步阐述。
实施例1
本发明药物有效成分的原料组成及重量为：
小构树叶30～45份、剪刀草30～45份、牛马藤25～40份、黄芪25～40份、
地瓜藤25～35份、丹参15～30份、石蝉草15～30份、钩藤根15～30份、
牛抄藤15～25份、东风草15～25份、芒硝10～20份、斑叶兰10～20份、
老鹳草10～20份、木通根9～15份、甘草9～15份、伸筋草9～15份、
当归9～15份、茉莉花露9～15份、白术9～15份、楼梯草3～12份、
小果蕗蕨3～12份、三棱3～9份、马蹬草1～6份、冰片1～3份。
本发明药物制备方法的工艺步骤为：
（1）将小构树叶、剪刀草、地瓜藤、钩藤根、牛抄藤、东风草、当归、白术、楼梯草、小果蕗蕨、三棱、马蹬草洗净后放入容器中，加入8-10倍量的蒸馏水浸泡4-5小时，加热煮沸3-4小时，提取浸液；再次加入6-8倍量的蒸馏水，加热煮沸2-3小时，提取浸液；最后再加入4-6倍量的蒸馏水，加热煮沸 1-2小时，提取浸液；合并三次浸液，过滤，得滤液备用；
（2）将牛马藤、石蝉草、斑叶兰、老鹳草、木通根、伸筋草洗净放入容器内，加入4倍量的浓度80%的乙醇溶液，浸泡1-2小时，加热回流提取3-4小时，过滤，得滤液备用；
（3）将黄芪片加炼熟的蜂蜜与少许开水，拌匀稍闷，放锅内炒至黄色并不粘手时，取出晾凉，粉碎研末，过140目细筛，得细粉，备用；
（4）取丹参片，加黄酒拌匀，闷润至透，置锅内，用文火炒，取出放凉，粉碎研末，过140目细筛，得细粉，备用；
（5）将芒硝粉碎研末，过140目细筛，得细粉，备用；
（6）取净甘草片，加入炼熟的蜂蜜与少许开水，拌匀后稍闷，置炒制容器内，文火炒至深黄色，不粘手时取出，放凉，粉碎研末，过140目细筛，得细粉，备用；
（7）将冰片粉碎研末，过140目细筛，得细粉，备用；
（8）将上述步骤(1)～(7)所制得的滤液和细粉以及茉莉花露混合后，加入8～10倍量的蒸馏水，搅拌溶解均匀后，加热煮沸0.5小时，至60℃以下，静置1小时，过滤，得滤液，将滤液灌装150ml药液袋包装封存，即得所述的中药熏洗药剂。
用法用量：将1袋本发明中药熏洗药剂倒入熏洗盆中，加适量水后搅拌均匀，加热至沸腾，先以药气熏蒸患处，待水温降至45℃左右时，将腿部浸入熏洗盆内，若水温下降可加温后再泡，每次熏洗时间不少于30 分钟，每日2次，7天为1疗程。
实施例2
本发明药物有效成分的原料组成及重量为：
小构树叶35～40份、剪刀草35～40份、牛马藤30～36份、黄芪30～36份、
地瓜藤28～33份、丹参20～25份、石蝉草20～25份、钩藤根20～25份、
牛抄藤18～22份、东风草18～22份、芒硝12～16份、斑叶兰12～16份、
老鹳草12～16份、木通根11～13份、甘草10～12份、伸筋草10～12份、
当归10～12份、茉莉花露10～12份、白术10～12份、楼梯草5～9份、
小果蕗蕨5～9份、三棱4～6份、马蹬草2～4份、冰片1～2份。
本实施例的药物制备方法工艺步骤及用法用量与实施例1相同。
实施例3
本发明药物有效成分的原料组成及重量为：
小构树叶36份、剪刀草36份、牛马藤33份、黄芪33份、
地瓜藤30份、丹参24份、石蝉草23份、钩藤根22份、
牛抄藤20份、东风草20份、芒硝15份、斑叶兰15份、
老鹳草15份、木通根12份、甘草11份、伸筋草10份、
当归10份、茉莉花露10份、白术10份、楼梯草6份、
小果蕗蕨6份、三棱5份、马蹬草3份、冰片1份。
本实施例的药物制备方法工艺步骤及用法用量与实施例1相同。
临床资料：
1、病例选择
选择我院确诊的淤积性皮炎患者62例临床观察，病人随机分成两组。治疗组32例，其中男性20例，女性12例，年龄39～67岁，平均年龄53.6岁。对照组30例，其中男性18例，女性12例，年龄38～65岁，平均年龄54.2岁。两组资历基本一致，无显著差异，具有可比性。
2、治疗方法
治疗组患者使用本发明中药熏洗药剂，将1袋本发明中药熏洗药剂倒入熏洗盆中，加适量水后搅拌均匀，加热至沸腾，先以药气熏蒸患处，待水温降至45℃左右时，将腿部浸入熏洗盆内，若水温下降可加温后再泡，每次熏洗时间不少于30 分钟，每日2次，7天为1疗程，治疗4个疗程。
对照组患者内服盐酸西替利嗪片，每次10mg，每日1次，患处外用丁酸氢化可的松乳膏，每日2次，7天为1疗程，治疗4个疗程。
3、疗效判定：
（1）痊愈：患处瘙痒、红肿、疼痛等症状消失，皮损消退，皮肤颜色基本恢复正常。
（2）好转：患处瘙痒、红肿、疼痛等症状明显减轻，皮损消退50％以上。
（3）无效：症状同施治前无明显改善。
4、结果
治疗组中治愈23例，好转7例，无效2例，治愈率71.9％，总有效率93.8％。
对照组中治愈11例，好转10例，无效9例，治愈率36.7％，总有效率70％。
以上结果显示，治疗组的治愈率和总有效率明显高于对照组。
典型病例举例：
1、齐××，男，56岁。该患者两脚踝部最初出现红斑，后逐渐扩大，瘙痒难耐，并有轻度鳞屑，皮肤呈深棕褐色斑块，下肢有水肿，情况愈发严重。后来来院问诊，诊断为淤积性皮炎，经使用本发明中药熏洗药剂4疗程后，上述症状完全消失，3个月未复发，已痊愈。
2、李××，男，58岁。该患者足踝部皮肤出现红斑，有轻度鳞屑，有痒感，几周后皮肤呈深褐色。后来来院问诊，诊断为淤积性皮炎，经使用本发明中药熏洗药剂3个疗程后，上述症状完全消失，3个月未复发，已痊愈。
3、蔡××，女，62岁。该患者双下肢轻微水肿，小腿前侧皮肤干燥脱屑，有压痛及痒感，表面呈苔藓样变，颜色逐渐变为褐色。后来来院问诊，诊断为淤积性皮炎，经使用本发明中药熏洗药剂4个疗程后，上述症状完全消失，3个月未复发，已痊愈。
淤积性皮炎与下肢静脉曲张，血液回流障碍组织缺氧水肿以及搔抓和磨擦有关，长期从事站立工作容易造成下肢静脉曲张者易患淤积性皮炎。本发明中药熏洗药剂根据病因对症下药，方中楼梯草、石蝉草可清热解毒、化瘀散结、利水消肿；方中伸筋草、老鹳草、地瓜藤可清热利湿、通经活络、消肿止痛；方中钩藤根、牛抄藤可舒筋活络；方中东风草、小构树叶可清热解毒、祛风止痒；方中木通根、剪刀草、斑叶兰可行气活血、解毒消肿；方中芒硝、三棱可破血行气通经、消肿疗疮；方中丹参、牛马藤、马蹬草可活血化瘀；方中白术、当归可益气补血、健脾助运；方中黄芪、小果蕗蕨、茉莉花露可补气固表、敛疮生肌、润泽肌肤；方中冰片可促进其他药物透皮吸收；方中甘草可调和诸药；方中诸药合用可共奏清热利湿、解毒消肿、破血行气、行气活血、化瘀散结、通经活络、舒筋活络、益气补血、祛风止痒、敛疮生肌之功效，通过中药外用熏洗，可直接使药物作用于患处，发挥药效，可改善局部血液循环，疏通瘀滞，杀菌消炎，敛疮收口，促进创面组织修复，吸收效果好，疗效显著，经临床验证对淤积性皮炎治愈率较高。
Claims (4)
1.一种用于治疗淤积性皮炎的中药熏洗药剂，其特征在于，制成所述药物有效成分的原料组成及重量份数为：
小构树叶30～45份、剪刀草30～45份、牛马藤25～40份、黄芪25～40份、
地瓜藤25～35份、丹参15～30份、石蝉草15～30份、钩藤根15～30份、
牛抄藤15～25份、东风草15～25份、芒硝10～20份、斑叶兰10～20份、
老鹳草10～20份、木通根9～15份、甘草9～15份、伸筋草9～15份、
当归9～15份、茉莉花露9～15份、白术9～15份、楼梯草3～12份、
小果蕗蕨3～12份、三棱3～9份、马蹬草1～6份、冰片1～3份。
2.根据权利要求1所述的一种用于治疗淤积性皮炎的中药熏洗药剂，其特征在于，制成所述药物有效成分的原料组成及重量份数为：
小构树叶35～40份、剪刀草35～40份、牛马藤30～36份、黄芪30～36份、
地瓜藤28～33份、丹参20～25份、石蝉草20～25份、钩藤根20～25份、
牛抄藤18～22份、东风草18～22份、芒硝12～16份、斑叶兰12～16份、
老鹳草12～16份、木通根11～13份、甘草10～12份、伸筋草10～12份、
当归10～12份、茉莉花露10～12份、白术10～12份、楼梯草5～9份、
小果蕗蕨5～9份、三棱4～6份、马蹬草2～4份、冰片1～2份。
3.根据权利要求1所述的一种用于治疗淤积性皮炎的中药熏洗药剂，其特征在于，制成所述药物有效成分的原料组成及重量份数为：
小构树叶36份、剪刀草36份、牛马藤33份、黄芪33份、
地瓜藤30份、丹参24份、石蝉草23份、钩藤根22份、
牛抄藤20份、东风草20份、芒硝15份、斑叶兰15份、
老鹳草15份、木通根12份、甘草11份、伸筋草10份、
当归10份、茉莉花露10份、白术10份、楼梯草6份、
小果蕗蕨6份、三棱5份、马蹬草3份、冰片1份。
4.如权利要求1～3任一所述的一种用于治疗淤积性皮炎的中药熏洗药剂，其特征在于，制备方法包括以下工艺步骤：
（1）将小构树叶、剪刀草、地瓜藤、钩藤根、牛抄藤、东风草、当归、白术、楼梯草、小果蕗蕨、三棱、马蹬草洗净后放入容器中，加入8-10倍量的蒸馏水浸泡4-5小时，加热煮沸3-4小时，提取浸液；再次加入6-8倍量的蒸馏水，加热煮沸2-3小时，提取浸液；最后再加入4-6倍量的蒸馏水，加热煮沸 1-2小时，提取浸液；合并三次浸液，过滤，得滤液备用；
（2）将牛马藤、石蝉草、斑叶兰、老鹳草、木通根、伸筋草洗净放入容器内，加入4倍量的浓度80%的乙醇溶液，浸泡1-2小时，加热回流提取3-4小时，过滤，得滤液备用；
（3）将黄芪片加炼熟的蜂蜜与少许开水，拌匀稍闷，放锅内炒至黄色并不粘手时，取出晾凉，粉碎研末，过140目细筛，得细粉，备用；
（4）取丹参片，加黄酒拌匀，闷润至透，置锅内，用文火炒，取出放凉，粉碎研末，过140目细筛，得细粉，备用；
（5）将芒硝粉碎研末，过140目细筛，得细粉，备用；
（6）取净甘草片，加入炼熟的蜂蜜与少许开水，拌匀后稍闷，置炒制容器内，文火炒至深黄色，不粘手时取出，放凉，粉碎研末，过140目细筛，得细粉，备用；
（7）将冰片粉碎研末，过140目细筛，得细粉，备用；
（8）将上述步骤(1)～(7)所制得的滤液和细粉以及茉莉花露混合后，加入8～10倍量的蒸馏水，搅拌溶解均匀后，加热煮沸0.5小时，至60℃以下，静置1小时，过滤，得滤液，将滤液灌装150ml药液袋包装封存，即得所述的中药熏洗药剂。
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