CN1086437A - 用白细胞介素-4抑制人免疫缺陷病毒复制的方法 - Google Patents

用白细胞介素-4抑制人免疫缺陷病毒复制的方法 Download PDF

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Publication number
CN1086437A
CN1086437A CN93116434A CN93116434A CN1086437A CN 1086437 A CN1086437 A CN 1086437A CN 93116434 A CN93116434 A CN 93116434A CN 93116434 A CN93116434 A CN 93116434A CN 1086437 A CN1086437 A CN 1086437A
Authority
CN
China
Prior art keywords
hiv
cell
interleukin
replication
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93116434A
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English (en)
Chinese (zh)
Inventor
J·许瓦兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CN1086437A publication Critical patent/CN1086437A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2026—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
CN93116434A 1992-08-19 1993-08-18 用白细胞介素-4抑制人免疫缺陷病毒复制的方法 Pending CN1086437A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93213492A 1992-08-19 1992-08-19
US932,134 1992-08-19

Publications (1)

Publication Number Publication Date
CN1086437A true CN1086437A (zh) 1994-05-11

Family

ID=25461831

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93116434A Pending CN1086437A (zh) 1992-08-19 1993-08-18 用白细胞介素-4抑制人免疫缺陷病毒复制的方法

Country Status (22)

Country Link
US (1) US5700461A (https=)
EP (1) EP0656785B1 (https=)
JP (1) JP2711182B2 (https=)
KR (1) KR950702838A (https=)
CN (1) CN1086437A (https=)
AT (1) ATE163860T1 (https=)
AU (1) AU683427B2 (https=)
CA (1) CA2142862C (https=)
CZ (1) CZ38095A3 (https=)
DE (1) DE69317428T2 (https=)
ES (1) ES2113549T3 (https=)
FI (1) FI950696A7 (https=)
HU (1) HUT72709A (https=)
IL (1) IL106717A0 (https=)
MX (1) MX9305016A (https=)
NO (1) NO950599D0 (https=)
NZ (1) NZ255735A (https=)
PL (1) PL307508A1 (https=)
SK (1) SK21295A3 (https=)
TW (1) TW291439B (https=)
WO (1) WO1994004179A1 (https=)
ZA (1) ZA936018B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69632062T2 (de) 1995-11-02 2004-11-18 Schering Corp. Kontinuierliche, niedrigdosierte zytokine-infusionstherapie
US20030232738A1 (en) * 1998-04-20 2003-12-18 National Jewish Medical And Research Center Method and composition for increasing CD4+ T lymphocyte immune responsiveness
US20050124645A1 (en) * 1998-04-20 2005-06-09 Finkel Terri H. Methods and compositions for increasing CD4lymphocyte immune responsiveness
US20040132161A1 (en) * 1998-04-20 2004-07-08 Finkel Terri H. Methods and compositions for increasing CD4lymphocyte immune responsiveness
CA2335617C (en) * 1998-06-24 2009-12-15 Novirio Pharmaceuticals Limited Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv
US6734192B1 (en) * 1999-08-23 2004-05-11 Mp-1 Inc. Treatment of viral infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
JPH02485A (ja) * 1987-08-03 1990-01-05 Yuu Honshiyo 新規なヒトインターロイキン４、該因子を発現させるための組換えベクター及びそのベクターにより形質転換された形質転換体
US5011829A (en) * 1989-06-02 1991-04-30 G. D. Searle & Co. Pharmaceutical composition and method of inhibiting virus
ZA912037B (en) * 1990-03-21 1992-03-25 Schering Corp Use of il-4 to enhance immune response to infectious antigenic challenges
US5206345A (en) * 1990-08-02 1993-04-27 Fred Hutchinson Cancer Research Center Il-4 and tnf induce mab 6g10-recognized expression on bone marrow stromal cells
EP0490006B1 (en) * 1990-12-13 1994-06-22 Schering-Plough Pharmaceutical compositions for the treatment of B-cell malignancies

Also Published As

Publication number Publication date
CA2142862C (en) 2000-05-30
US5700461A (en) 1997-12-23
EP0656785B1 (en) 1998-03-11
PL307508A1 (en) 1995-05-29
HUT72709A (en) 1996-05-28
EP0656785A1 (en) 1995-06-14
NZ255735A (en) 1997-06-24
FI950696L (fi) 1995-02-16
KR950702838A (ko) 1995-08-23
TW291439B (https=) 1996-11-21
IL106717A0 (en) 1993-12-08
DE69317428D1 (de) 1998-04-16
DE69317428T2 (de) 1998-07-02
MX9305016A (es) 1994-02-28
ATE163860T1 (de) 1998-03-15
JP2711182B2 (ja) 1998-02-10
FI950696A0 (fi) 1995-02-16
SK21295A3 (en) 1997-01-08
CZ38095A3 (en) 1995-12-13
CA2142862A1 (en) 1994-03-03
FI950696A7 (fi) 1995-02-16
ES2113549T3 (es) 1998-05-01
JPH07506116A (ja) 1995-07-06
NO950599L (no) 1995-02-17
AU5007593A (en) 1994-03-15
ZA936018B (en) 1994-06-13
WO1994004179A1 (en) 1994-03-03
NO950599D0 (no) 1995-02-17
AU683427B2 (en) 1997-11-13
HU9500487D0 (en) 1995-04-28

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