CN108635525A - A kind of amber determines epilepsy capsule and preparation method thereof - Google Patents
A kind of amber determines epilepsy capsule and preparation method thereof Download PDFInfo
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- CN108635525A CN108635525A CN201810849104.8A CN201810849104A CN108635525A CN 108635525 A CN108635525 A CN 108635525A CN 201810849104 A CN201810849104 A CN 201810849104A CN 108635525 A CN108635525 A CN 108635525A
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- amber
- epilepsy
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- cinnabar
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- 206010015037 epilepsy Diseases 0.000 title claims abstract description 38
- 239000002775 capsule Substances 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 239000000843 powder Substances 0.000 claims abstract description 22
- 229910052956 cinnabar Inorganic materials 0.000 claims abstract description 19
- 244000001632 Acorus gramineus Species 0.000 claims abstract description 13
- 235000013073 Acorus gramineus Nutrition 0.000 claims abstract description 13
- 241000157352 Uncaria Species 0.000 claims abstract description 13
- 241000255789 Bombyx mori Species 0.000 claims abstract description 12
- 241000361919 Metaphire sieboldi Species 0.000 claims abstract description 12
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 12
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 12
- 244000197580 Poria cocos Species 0.000 claims abstract description 12
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 12
- 235000008434 ginseng Nutrition 0.000 claims abstract description 12
- 241000931143 Gleditsia sinensis Species 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 241000208340 Araliaceae Species 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 239000006071 cream Substances 0.000 claims description 6
- 238000005498 polishing Methods 0.000 claims description 6
- 238000007873 sieving Methods 0.000 claims description 4
- 238000003860 storage Methods 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 14
- 229940079593 drug Drugs 0.000 abstract description 8
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 6
- 208000026435 phlegm Diseases 0.000 abstract description 6
- 239000004480 active ingredient Substances 0.000 abstract description 4
- 230000007774 longterm Effects 0.000 abstract description 3
- 230000002936 tranquilizing effect Effects 0.000 abstract description 2
- 229920002892 amber Polymers 0.000 abstract 3
- 241000196324 Embryophyta Species 0.000 abstract 1
- 206010029333 Neurosis Diseases 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract 1
- 206010022437 insomnia Diseases 0.000 abstract 1
- 230000036461 convulsion Effects 0.000 description 7
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 206010010904 Convulsion Diseases 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- 241001251949 Xanthium sibiricum Species 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 230000001037 epileptic effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 208000021760 high fever Diseases 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000030886 Traumatic Brain injury Diseases 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000016097 disease of metabolism Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 229940126534 drug product Drugs 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
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- 208000015181 infectious disease Diseases 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 244000145591 rattan cane Species 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/10—Peat; Amber; Turf; Humus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/06—Fungi, e.g. yeasts
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- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a kind of ambers to determine epilepsy capsule, includes the raw material of following parts by weight：76 81g of grass-leaved sweetflag, 80 83g of uncaria, 30 35g of stiff silkworm, 13 15g of ginseng, 40 45g of amber, 30 33g of Poria cocos, 30 35g of caulis bambusae in taenian, 30 33g of Rhizoma Atractylodis Macrocephalae, 30 35g of gleditsia sinensis, 40 43g of earthworm, 16 20g of cinnabar, 40 43g of pearl powder.The present invention provides a kind of ambers to determine epilepsy capsule preparation method thereof.Stable quality of the present invention, safely, effectively, have the function of preferable clearing heat-fire, wash phlegm and open strongly fragrant, tranquilizing and allaying excitement etc., it is disorderly that insane, mad, epilepsy, depression, insomnia, psychasthenia and plant god essence function can effectively be treated, solves decoction decocting, inconvenient to carry in the prior art simultaneously, the problem of being not easy to patient medication, and the active ingredient of crude drug is remained well, be conducive to patient's long-term use.
Description
Technical field
The present invention relates to pharmaceutical technology fields more particularly to a kind of amber to determine epilepsy capsule and preparation method thereof.
Background technology
There are many reason of causing epileptic attack：Caused by having lesion or the diffused lesion of brain, also have systemic
Caused by metabolism poisoning, also some causes are unknown so far.Clinically common pathogenic factor is with brain trauma, brain tumor, brain blood
Pipe disease, intracranial infection etc. seem even more important.The epilepsy caused by the above-mentioned clear cause of disease, medically claims secondary epilepsy, or
Claim symptomatic epilepsy.In addition to this, some are without brain is organic and metabolic disease performance, pathogenesis it is not yet clear one
Class epilepsy, referred to as idiopathic epilepsy or idiopathy.
Chinese medicine thinks that epilepsy is to lead to the heart, liver,spleen,kidney, visceral-qi imbalance, liver kidney yin by wind, fire, phlegm, the stasis of blood to suffer from
Then positive high, the high then liver wind agitation of sun, high and excess heat, excess heatization fire, fire extremely make wind, the help of wind fire to suffer to the empty, deficiency of Yin, another spleen deficiency mistake
Fortune, clear gas do not rise, foul smell does not drop that then knot in sputum, in blinded judgment, painstaking effort are unsuccessful and the stasis of blood, the stasis of blood then blockage of main and collateral channels, on phlegm resistance blood stasis
Clear key is disturbed, causes epileptic attack eventually.According to pathogenesis, frequently with determining, epilepsy relieves dizziness, high fever, infantile convulsions, epilepsy, etc., soothing the liver purging intense heat, eliminating the phlegm are had one's ideas straightened out, promoting blood circulation and removing blood stasis is
Therapy, clinical effectiveness hang in the balance, and mostly based on decoction, but due to decoction decocting, cannot be effectively retained active compound
The active ingredient of material, it is inconvenient to carry, be not easy to patient medication, in addition prescribed preparation, each dosing dosage is smaller, effect compared with
It is micro-, so being badly in need of one kind being conducive to patient's long-term use, and it is effectively retained the active ingredient of crude drug, the preparation side of definite effect
Method.
Invention content
Technical problems based on background technology, the present invention propose a kind of amber and determine epilepsy capsule and preparation method thereof.
A kind of amber proposed by the present invention determines epilepsy capsule, includes the raw material of following parts by weight：Grass-leaved sweetflag 76-81g, uncaria
80-83g, stiff silkworm 30-35g, ginseng 13-15g, amber 40-45g, Poria cocos 30-33g, caulis bambusae in taenian 30-35g, Rhizoma Atractylodis Macrocephalae 30-33g, gleditsia sinensis
30-35g, earthworm 40-43g, cinnabar 16-20g, pearl powder 40-43g.
A kind of amber determines epilepsy capsule and preparation method thereof, includes the following steps：
S1：It is prepared by raw material：Grass-leaved sweetflag, earthworm, ginseng, stiff silkworm, amber, cinnabar, pearl powder is chosen to clean out, uncaria,
Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar wash with water totally；
S2：Raw material mixing crushes：Grass-leaved sweetflag, earthworm, ginseng, stiff silkworm, amber, cinnabar, pearl powder described in S1 is mixed
It closes uniformly, is ground into fine powder, be sieved；
S3：Boil liquid：Uncaria, Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar add water to cook twice, merge decoction liquor twice, concentration
At cream；
S4：Dry, crushing：By cream and the medicinal powder crushed, low temperature drying, then it is ground into fine powder, is sieved；
S5：Encapsulating, polishing：Fine powder is poured into capsule, polishing, finished product is made；
S6：Bottling storage；
Preferably, in the S2, sieving referred to 80 mesh sieve.
Preferably, in the S3, uncaria, Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar are added water to cook 2 hours for the first time, the
Secondary 1.5 hours.
Preferably, in the S4, sieving, which refers to, to be sieved with 100 mesh sieve.
Compared with the prior art, the beneficial effects of the invention are as follows：Determine epilepsy with amber, pearl, tranquilizing cinnabar for monarch, earthworm,
The resolving sputum that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. of uncaria, stiff silkworm, caulis bambusae in taenian relieving convulsion is minister, estimates with ginseng, Rhizoma Atractylodis Macrocephalae, the strengthening the spleen and replenishing qi of cloud Siberian cocklebur, eliminating dampness and eliminating phlegm, makes with grass-leaved sweetflag
Gods are walked on agile, consciousness regaining, such compatibility, hit the interpretation of the cause, onset and process of an illness, and effect is preferred.The present invention draws successive dynasties famous expert and treats epilepsy
Experience selects grass-leaved sweetflag, uncaria, stiff silkworm, ginseng, amber, Fu in conjunction with Chinese medicine modern pharmacology research to this disease differentiation of symptoms and signs for classification of syndrome
The medicinal materials such as Siberian cocklebur, caulis bambusae in taenian are refined into amber and determine epilepsy capsule, have the function of breath wind that reduces phlegm, only jerk and determine epilepsy, for treating epilepsy, twitch
And various complication.The problem of solving decoction decocting, inconvenient to carry in the prior art simultaneously, being not easy to patient medication, and
The active ingredient for remaining crude drug well is conducive to patient's long-term use.
Specific implementation mode
With reference to specific embodiment, the present invention is further elaborated.
Embodiment one
1. proposing a kind of amber in the present invention determines epilepsy capsule, include the raw material of following parts by weight：Grass-leaved sweetflag 76-81g, hook
Rattan 80-83g, stiff silkworm 30-35g, ginseng 13-15g, amber 40-45g, Poria cocos 30-33g, caulis bambusae in taenian 30-35g, Rhizoma Atractylodis Macrocephalae 30-33g, soap
Angle 30-35g, earthworm 40-43g, cinnabar 16-20g, pearl powder 40-43g.
2. the preparation method that a kind of amber determines epilepsy capsule includes the following steps：
S1：It is prepared by raw material：Grass-leaved sweetflag, earthworm, ginseng, stiff silkworm, amber, cinnabar, pearl powder is chosen to clean out, uncaria,
Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar wash with water totally；
S2：Raw material mixing crushes：Grass-leaved sweetflag, earthworm, ginseng, stiff silkworm, amber, cinnabar, pearl powder described in S1 is mixed
It closes uniformly, is ground into fine powder, be sieved；
S3：Boil liquid：Uncaria, Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar add water to cook twice, merge decoction liquor twice, concentration
At cream；
S4：Dry, crushing：By cream and the medicinal powder crushed, low temperature drying, then it is ground into fine powder, is sieved；
S5：Encapsulating, polishing：Fine powder is poured into capsule, polishing, finished product is made；
S6：Bottling storage；
Usage and dosage：It is oral, one time 2~5,3 times a day, children are cut down according to the circumstance, or are followed the doctor's advice.
3. stability of drug products and safety experiment
(1) capsule that will be made by the above method, respectively establishment are numbered：20040304、20040310、20040316；
(2) grass-leaved sweetflag control medicinal material, earthworm control medicinal material：It is purchased from Nat'l Pharmaceutical ＆ Biological Products Control Institute；
(3) water (pure water)；Methanol, ethyl alcohol, dichloromethane, ethyl acetate etc. are AR grades of domestic reagent；
(4) ZF-I types ultraviolet analysis instrument for three purposed；
Detection project is as follows：
1 sample ID amber of table determines epilepsy capsule lot number：20040304
2 sample ID amber of table determines epilepsy capsule lot number：20040310
3 sample ID of table：Amber determines epilepsy capsule lot number：20040316
Our three batches of sample reserved sample observing results to preparation of root Ju：" amber determines epilepsy capsule " in appearance character, differentiate, defend
Raw, moisture, dissolution etc. all change without conspicuousness, meet the requirement that amber determines epilepsy capsule quality standard, show " amber
Amber determines epilepsy capsule " it is more stable.In addition, amber determines the mouth that epilepsy capsule is packed for the production of Cang County rehabilitation acceptable packaging material factory
Oral solid plastic drug package is on the quality of preparation without influence, this preparation is stable during the experiment, and preparation storage life is 1 year.
4. model case is illustrated：
1, Chen, man, 39 years old, worker, the diagnosis of in September, 2014 suffered from epilepsy 2 years.Be it is frightened after cause, initially monthly
Number hair, closely breaking-out daily over the past half year, hair is then senseless, scream twitch, stiffness of the nape and back, slobbering, and breaking-out every time lasts about
Eight to 12 minutes, Western medicine was used repeatly, fails to control.Thirsty spontaneous perspiration.Tongue is thin white, floating-rolling pulse.It is dialectical：Gasify not all right, water drinks punching.
After taking 6 box of this medicine, breaking-out has been controlled, after taking 24 boxes, clinical cure.After treatment 3 years without recurrence.
2, certain is thanked, female, 46 years old, peasant, in May, 2015, diagnosis, had a convulsion, situation of spitting out white foams for nearly 1 year often, used
It cannot thoroughly be improved always, be hung in the balance after medicine, it is very worried thus, cause unhappy, the situations such as apocleisis.Come institute to hold
It is continuous to take medicine 3 months, hence it is evident that have controlled the state of an illness, treated through half a year medication, rehabilitation at present, without repeatedly.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (5)
1. a kind of amber determines epilepsy capsule, which is characterized in that include the raw material of following parts by weight：Grass-leaved sweetflag 76-81g, uncaria 80-
83g, stiff silkworm 30-35g, ginseng 13-15g, amber 40-45g, Poria cocos 30-33g, caulis bambusae in taenian 30-35g, Rhizoma Atractylodis Macrocephalae 30-33g, gleditsia sinensis 30-
35g, earthworm 40-43g, cinnabar 16-20g, pearl powder 40-43g.
2. a kind of amber according to claim 1 determines epilepsy capsule preparation method thereof, which is characterized in that include the following steps：
S1：It is prepared by raw material：Choose grass-leaved sweetflag, earthworm, ginseng, stiff silkworm, amber, cinnabar, pearl powder are cleaned out, uncaria, Poria cocos,
Caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar wash with water totally；
S2：Raw material mixing crushes：Grass-leaved sweetflag, earthworm, ginseng, stiff silkworm, amber, cinnabar, pearl powder described in S1 is mixed equal
It is even, it is ground into fine powder, is sieved；
S3：Boil liquid：Uncaria, Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar add water to cook twice, merge decoction liquor twice, are condensed into
Cream；
S4：Dry, crushing：By cream and the medicinal powder crushed, low temperature drying, then it is ground into fine powder, is sieved；
S5：Encapsulating, polishing：Fine powder is poured into capsule, polishing, finished product is made；
S6：Bottling storage.
3. a kind of amber according to claim 2 determines epilepsy capsule preparation method thereof, which is characterized in that in the S2, sieving refers to
Cross 80 mesh sieve.
4. a kind of amber according to claim 2 determines epilepsy capsule preparation method thereof, which is characterized in that in the S3, by uncaria,
Poria cocos, caulis bambusae in taenian, Rhizoma Atractylodis Macrocephalae, gleditsia sinensis, cinnabar add water to cook 2 hours for the first time, second 1.5 hours.
5. a kind of amber according to claim 2 determines epilepsy capsule preparation method thereof, which is characterized in that in the S4, sieving refers to
It sieves with 100 mesh sieve.
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| CN201810849104.8A CN108635525A (en) | 2018-07-28 | 2018-07-28 | A kind of amber determines epilepsy capsule and preparation method thereof |
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Citations (2)
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| CN102552713A (en) * | 2012-02-28 | 2012-07-11 | 卢卫平 | Medicine for treating epilepsy and preparation method thereof |
| CN104107204A (en) * | 2014-08-08 | 2014-10-22 | 何德亮 | Medicinal composition for treating encephalatrophy and facial paralysis |
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2018
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552713A (en) * | 2012-02-28 | 2012-07-11 | 卢卫平 | Medicine for treating epilepsy and preparation method thereof |
| CN104107204A (en) * | 2014-08-08 | 2014-10-22 | 何德亮 | Medicinal composition for treating encephalatrophy and facial paralysis |
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| 何清湖: "《现代名医用方心得》", 30 June 2013 * |
| 周农等: "癫痫宁冲剂治疗癫痫自主神经性发作的临床观察", 《上海中医药大学学报》 * |
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