CN108635383A - Sea-buckthorn salt cream and preparation method thereof - Google Patents

Sea-buckthorn salt cream and preparation method thereof Download PDF

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Publication number
CN108635383A
CN108635383A CN201810862380.8A CN201810862380A CN108635383A CN 108635383 A CN108635383 A CN 108635383A CN 201810862380 A CN201810862380 A CN 201810862380A CN 108635383 A CN108635383 A CN 108635383A
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buckthorn
sea
salt
mass ratio
filtrate
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刘忠
郭敏
吴志坚
张慧芳
刘海宁
叶秀深
王世栋
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Qinghai Institute of Salt Lakes Research of CAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Natural Medicines & Medicinal Plants (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Medical Informatics (AREA)
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  • Medicinal Preparation (AREA)

Abstract

The present invention provides a kind of sea-buckthorn salt cream comprising according to mass ratio be 3:1~8:1 uniformly mixed sea-buckthorn/mix lubricant body and salt;Wherein, sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, and lubricant includes vaseline and glycerine, and the mass ratio of sea-buckthorn filtrate and vaseline is 3:1~6:1, the mass ratio of vaseline and glycerine is 0.5:1~3:1.The present invention also provides the preparation methods of above-mentioned sea-buckthorn salt cream.The effect of present invention, which makes full use of to burn, scald, knife burning, frostbite, has the sea-buckthorn filtrate of good therapeutic effect to prepare a kind of completely new function salt, and wherein salt can not only play the medicinal component for keeping sea-buckthorn while can also play antibacterial anti-inflammatory;The sea-buckthorn salt cream can obtain the effect of promoting blood circulation to remove blood stasis and treatment scald by being directly coated with.It compared to the preparation method of other function salt, avoids using supercritical carbon dioxide extracting or conventional Traditional Chinese medicine extraction method etc., therefore avoids the shortcomings of preparation process is complicated and manufacturing cost is high.

Description

Sea-buckthorn salt cream and preparation method thereof
Technical field
The invention belongs to health medicine technical fields, it relates in particular to a kind of sea-buckthorn salt cream and preparation method thereof.
Background technology
With the continuous enhancing of people's health consciousness, domestic function salt is gradually to compound, multi items, nutrient laden and work( Energyization develops, and has also gradually appeared the work(such as organic salt compounded of iodine, Cardia Salt, selenium-rich salt, amino-acid salt, matrimony vine salt, sea-buckthorn salt on the market It can property product salt.Salt has the function of antibacterial anti-inflammatory, and sea-buckthorn burns burn, scald, knife, frostbite has good therapeutic effect. But the research of the functional cream salt of mixing sea-buckthorn and salt is less in technology at present, such as prepares the technical method of health-care hippophae rhamnoide salt, It uses cAMP, colors, vitamin, triterpenic acid and protein in supercritical carbon dioxide extracting matrimony vine and sea-buckthorn etc. Its aqueous solution is then added in sodium chloride saturated solution by functional component, and reduction vaporization obtains health-care salt;And with food Salt, hippophae rhamnoides, Chinese medicine powder, broad bean powder, wheat flour, millet, high protein additive, potassium alginate, almond, walnut kernel, Hawthorn, monosodium glutamate, sweetener, antioxidant, ground cinnamon, fennel powder, pepper powder, high-protein agent, vitamin enrichment agent and mine Substance hardening agent etc. prepares healthy salt, but it is mainly functional table salt using atmosphere.
Vitamin C content is very high in sea buckthorn fruit, there is the laudatory title of the king of vitamin C, contains 400mg in every 100g sea-buckthorn pulp ~500mg vitamin Cs and other vitamins, as 250mg~400mg vitamin Es, 0.05mg~0.3mg vitamin B1s, 0.03mg~0.15mg vitamin B2s, 0.2mg~0.88mg vitamin B12s, 115mg or so vitamin K compounds of group and 20mg~350mg P family vitamins etc..In addition, the various amino acid also wanted containing needed by human body, aliphatic acid, linoleic acid, sea-buckthorn The yellow paulownia objects of 7 kinds of flavones, hepatocuprein (SOD) isoreactivity substance and Isorhamnetin, glucoside, Quercetin, Kaempferol etc. Matter and trace element.Sea buckthorn fruit contains abundant nutriment and the substance of bioactivity, and sea buckthorn fruit is used as medicine with only The effect of cough resolving sputum, stomach strengthening and digestion promoting, promoting blood circulation to remove blood stasis, external application are used to burn, scald, knife are burnt, frostbite has and controls well Treatment acts on.
As it can be seen that on the one hand too many currently based on composition addition type in the function salt of sea-buckthorn so that the function embodiment of sea-buckthorn It is not obvious;On the other hand at present for ointment such as burn, scald, knife burning, frostbite, be usually present plurality of Chinese effectively at Part, and need to add a variety of anti-corrosion additives and additive, composition and technique are relative complex, and cost is higher.
Therefore, if can by sea buckthorn fruit by Application of composite in plaster, can will realize to big degree the medical work(of sea-buckthorn Effect.
Invention content
To solve the above-mentioned problems of the prior art, the present invention provides a kind of sea-buckthorn salt cream, the sea-buckthorn salt cream is abundant Using sea-buckthorn to the pharmacologic action of burn, scald, knife burning, frostbite etc., in conjunction with lubricant and the antimicrobial and anti-inflammation efficacy of salt, at This is cheap and simple for process.
In order to reach foregoing invention purpose, present invention employs the following technical solutions:
A kind of sea-buckthorn salt cream comprising according to mass ratio be 3:1~8:1 uniformly mixed sea-buckthorn/mix lubricant body with Salt;Wherein, the sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, and the lubricant includes Vaseline and glycerine;Also, the mass ratio of the sea-buckthorn filtrate and vaseline is 3:1~6:1, the mass ratio of vaseline and glycerine It is 0.5:1~3:1.
Further, the sea-buckthorn filtrate be fresh sea-buckthorn or sea-buckthorn do it is agitated, broken in medicinal alcohol/water mixture It is broken and leach, filter and obtain.
Further, in the medicinal alcohol/water mixture, the mass ratio of medicinal alcohol and water is 1:3~3:1;When When the sea-buckthorn filtrate derives from fresh sea-buckthorn, then the mass ratio of the water in the fresh sea-buckthorn and the medicinal alcohol/water mixture It is 1:3~1:8;When the sea-buckthorn filtrate is done from sea-buckthorn, then the sea-buckthorn it is dry in the medicinal alcohol/water mixture Water mass ratio be 1:10~1:15.
Further, extraction time is 12h~48h.
Further, the grain size of the salt is less than 100 mesh.
Another object of the present invention is to provide a kind of preparation methods of sea-buckthorn salt cream comprising step:
S1, fresh sea-buckthorn or sea-buckthorn are done into agitated, broken, leaching, filtering acquisition sea-buckthorn in medicinal alcohol/water mixture Filtrate;
S2, by the sea-buckthorn filtrate and lubricant according to mass ratio it is 0.5:1~6:1 is uniformly mixed, and obtains sea-buckthorn/lubrication Agent mixture;The lubricant includes vaseline and glycerine;Also, the sea-buckthorn filtrate is 3 according to mass ratio with vaseline:1 ~6:1 mixing, vaseline are 0.5 according to mass ratio with glycerine:1~3:1 mixing;
S3, by the sea-buckthorn/mix lubricant body and salt according to mass ratio it is 3:1~8:1 is uniformly mixed, and obtains sea-buckthorn Salt cream.
Further, in the step S1, in the medicinal alcohol/water mixture, the quality of medicinal alcohol and water Than being 1:3~3:1;When using the fresh sea-buckthorn, then the matter of the water in the fresh sea-buckthorn and the medicinal alcohol/water mixture Amount is than being 1:3~1:8;When dry using the sea-buckthorn, then the sea-buckthorn does and the water in the medicinal alcohol/water mixture Mass ratio is 1:10~1:15.
Further, in the step S1, extraction time is 12h~48h.
Further, in the step S3, the grain size of the salt is less than 100 mesh.
The present invention is by selecting to burn, scald, knife are burnt, frostbite has the sea-buckthorn filtrate of good therapeutic effect to prepare one The completely new function salt of kind, and the presence of wherein salt can not only play the medicinal component for keeping sea-buckthorn while can also play anti- The effect of bacterium anti-inflammatory;The sea-buckthorn salt cream obtained can obtain the effect of promoting blood circulation to remove blood stasis and treatment scald by being directly coated with. The preparation method of the sea-buckthorn salt cream is simple, compared with prior art in other function salt preparation method, avoid using overcritical Carbon dioxide abstraction or conventional Traditional Chinese medicine extraction method etc., thus also avoid the preparation process present in these methods it is complicated and The shortcomings of manufacturing cost is high.
Specific implementation mode
Hereinafter, detailed description of the present invention embodiment in future.However, it is possible to implement this hair in many different forms It is bright, and the present invention should not be construed as limited to the specific embodiment illustrated here.On the contrary, provide these embodiments be for Explanation the principle of the present invention and its practical application, to make others skilled in the art it will be appreciated that the present invention's is various Embodiment and the various modifications for being suitable for specific intended application.
The present invention provides a kind of completely new function salt, are a kind of sea-buckthorn salt cream comprising according to mass ratio be 3:1~ 8:1 uniformly mixed sea-buckthorn/mix lubricant body and salt;And wherein sea-buckthorn/mix lubricant body includes uniformly mixed Sea-buckthorn filtrate and lubricant, lubricant specifically include vaseline and glycerine;Also, the mass ratio of sea-buckthorn filtrate and vaseline is 6: 1~6:1, and the mass ratio of vaseline and glycerine is 0.5:1~3:1.
Specifically, sea-buckthorn filtrate is that fresh sea-buckthorn or sea-buckthorn do agitated, broken in medicinal alcohol/water mixture and soak Go out, filter and obtain;Also, in medicinal alcohol/water mixture, the mass ratio of medicinal alcohol and water is 1:3~3:1;Work as sand When spine filtrate derives from fresh sea-buckthorn, then the mass ratio of fresh sea-buckthorn and the water in medicinal alcohol/water mixture is 1:3~1:8, and work as When sea-buckthorn filtrate is done from sea-buckthorn, then the dry mass ratio with the water in medicinal alcohol/water mixture of sea-buckthorn is 1:10~1:15.
At the same time, preferably control extraction time is 12h~48h.
Further, in the sea-buckthorn salt cream, the size controlling of salt is less than 100 mesh.
In this way, in the sea-buckthorn salt cream of the present invention, wherein having given full play to burn, scald, knife are burnt, frostbite has well The medicinal efficacy of the sea-buckthorn filtrate of therapeutic effect, at the same the presence of wherein salt can not only play keep sea-buckthorn medicinal component, The effect of capable of also playing antibacterial anti-inflammatory simultaneously;The sea-buckthorn salt cream obtained can obtain promoting blood circulation to remove blood stasis by being directly coated with and control The effect for the treatment of scald.
The present invention also provides the preparation methods of above-mentioned sea-buckthorn salt cream, i.e., with reference to following step:
In step sl, fresh sea-buckthorn or sea-buckthorn are done into agitated, broken, leaching, filtering in medicinal alcohol/water mixture Obtain sea-buckthorn filtrate.
Specifically, in the medicinal alcohol/water mixture, the mass ratio of medicinal alcohol and water is 1:3~3:1.
More specifically, when making sea-buckthorn filtrate, controlling fresh sea-buckthorn and medicinal alcohol/water mixture using fresh sea-buckthorn In water mass ratio be 1:3~1:8;And it is done and medical wine when using sea-buckthorn is dry when making sea-buckthorn filtrate, then to control sea-buckthorn The mass ratio of water in essence/water mixture is 1:10~1:15.
Further, it is preferable to which it is 12h~48h to control extraction time.
In step s 2, sea-buckthorn filtrate and mix lubricant is uniform, obtain sea-buckthorn/mix lubricant body.
Specifically, lubricant includes vaseline and glycerine;Also, sea-buckthorn filtrate is 3 according to mass ratio with vaseline:1 ~6:1 mixing, vaseline are 0.5 according to mass ratio with glycerine:1~3:1 mixing.
In step s3, it is 3 according to mass ratio by sea-buckthorn/mix lubricant body and salt:1~8:1 is uniformly mixed, and obtains Sea-buckthorn salt cream.
Preferably, selection grain size is mixed less than the salt of 100 mesh with sea-buckthorn/mix lubricant body.
The preparation method of sea-buckthorn salt cream provided by the invention compared with prior art in other function salt preparation method, avoid Using supercritical carbon dioxide extracting or conventional Traditional Chinese medicine extraction method etc., therefore also avoid the system present in these methods The shortcomings of standby complex process and high manufacturing cost.
It will illustrate the above-mentioned sea-buckthorn salt cream and preparation method thereof of the present invention by specific embodiment below.
Embodiment 1
(1) by fresh sea-buckthorn, water and medicinal alcohol in mass ratio 1:3:1 mixing, mechanical agitation is broken, static soak 12h After filtered, obtain sea-buckthorn filtrate.
(2) by the sea-buckthorn filtrate of acquisition and vaseline, glycerine according to mass ratio 3:1:2, which are mixed to get sea-buckthorn/lubricant, mixes It is fit.
(3) it is 3 according to mass ratio by sea-buckthorn/mix lubricant body and 100 mesh salt below:1 mixing, is made sea-buckthorn salt Cream.
That is, being 3 in sea-buckthorn salt cream provided in this embodiment, including according to mass ratio:1 uniformly mixed sand Spine/mix lubricant body and salt;Wherein, sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, and Lubricant specifically includes vaseline and glycerine, and the mass ratio of sea-buckthorn filtrate and vaseline is 3:1, the mass ratio of vaseline and glycerine It is 0.5:1.
Embodiment 2
(1) by fresh sea-buckthorn, water and medicinal alcohol in mass ratio 1:8:24 mixing, mechanical agitation is broken, static soak 48h After filtered, obtain sea-buckthorn filtrate.
(2) by the sea-buckthorn filtrate of acquisition and vaseline, glycerine according to mass ratio 3:1:2, which are mixed to get sea-buckthorn/lubricant, mixes It is fit.
(3) it is 8 according to mass ratio by sea-buckthorn/mix lubricant body and 100 mesh salt below:1 mixing, is made sea-buckthorn salt Cream.
That is, being 8 in sea-buckthorn salt cream provided in this embodiment, including according to mass ratio:1 uniformly mixed sand Spine/mix lubricant body and salt;Wherein, sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, and Lubricant specifically includes vaseline and glycerine, and the mass ratio of sea-buckthorn filtrate and vaseline is 3:1, the mass ratio of vaseline and glycerine It is 0.5:1.
Embodiment 3
(1) dry, water and medicinal alcohol in mass ratio 1 by sea-buckthorn:10:30 mixing, mechanical agitation is broken, static soak 12h After filtered, obtain sea-buckthorn filtrate.
(2) by the sea-buckthorn filtrate of acquisition and vaseline, glycerine according to mass ratio 3:1:2, which are mixed to get sea-buckthorn/lubricant, mixes It is fit.
(3) it is 3 according to mass ratio by sea-buckthorn/mix lubricant body and 100 mesh salt below:1 mixing, is made sea-buckthorn salt Cream.
That is, being 3 in sea-buckthorn salt cream provided in this embodiment, including according to mass ratio:1 uniformly mixed sand Spine/mix lubricant body and salt;Wherein, sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, and Lubricant specifically includes vaseline and glycerine, and the mass ratio of sea-buckthorn filtrate and vaseline is 3:1, the mass ratio of vaseline and glycerine It is 0.5:1.
Embodiment 4
(1) dry, water and medicinal alcohol in mass ratio 1 by sea-buckthorn:15:5 mixing, mechanical agitation is broken, after static soak 48h It is filtered, obtains sea-buckthorn filtrate.
(2) by the sea-buckthorn filtrate of acquisition and vaseline, glycerine according to mass ratio 18:3:1, which is mixed to get sea-buckthorn/lubricant, mixes It is fit.
(3) it is 8 according to mass ratio by sea-buckthorn/mix lubricant body and 100 mesh salt below:1 mixing, is made sea-buckthorn salt Cream.
That is, being 8 in sea-buckthorn salt cream provided in this embodiment, including according to mass ratio:1 uniformly mixed sand Spine/mix lubricant body and salt;Wherein, sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, and Lubricant specifically includes vaseline and glycerine, and the mass ratio of sea-buckthorn filtrate and vaseline is 6:1, the mass ratio of vaseline and glycerine It is 3:1.
Although the present invention has shown and described with reference to specific embodiment, it should be appreciated by those skilled in the art that: In the case where not departing from the spirit and scope of the present invention limited by claim and its equivalent, can carry out herein form and Various change in details.

Claims (9)

1. a kind of sea-buckthorn salt cream, which is characterized in that including being 3 according to mass ratio:1~8:1 uniformly mixed sea-buckthorn/lubricant is mixed Fit and salt;Wherein, the sea-buckthorn/mix lubricant body includes uniformly mixed sea-buckthorn filtrate and lubricant, the lubrication Agent includes vaseline and glycerine;Also, the mass ratio of the sea-buckthorn filtrate and vaseline is 3:1~6:1, vaseline and glycerine Mass ratio is 0.5:1~3:1.
2. sea-buckthorn salt cream according to claim 1, which is characterized in that the sea-buckthorn filtrate is that fresh sea-buckthorn or sea-buckthorn do in doctor With agitated, broken in alcohol/water mixture and leach, filter and obtain.
3. sea-buckthorn salt cream according to claim 2, which is characterized in that in the medicinal alcohol/water mixture, medical wine The mass ratio of essence and water is 1:3~3:1;When the sea-buckthorn filtrate derive from fresh sea-buckthorn when, then the fresh sea-buckthorn with it is described medical The mass ratio of water in alcohol/water mixture is 1:3~1:8;When the sea-buckthorn filtrate is done from sea-buckthorn, then the sea-buckthorn The dry mass ratio with the water in the medicinal alcohol/water mixture is 1:10~1:15.
4. sea-buckthorn salt cream according to claim 2, which is characterized in that extraction time is 12h~48h.
5. sea-buckthorn salt cream according to claim 1, which is characterized in that the grain size of the salt is less than 100 mesh.
6. a kind of preparation method of sea-buckthorn salt cream, which is characterized in that including step:
S1, fresh sea-buckthorn or sea-buckthorn are done into agitated, broken, leaching, filtering acquisition sea-buckthorn filter in medicinal alcohol/water mixture Liquid;
S2, by the sea-buckthorn filtrate and lubricant according to mass ratio it is 0.5:1~6:1 is uniformly mixed, and it is mixed to obtain sea-buckthorn/lubricant It is fit;The lubricant includes vaseline and glycerine;Also, the sea-buckthorn filtrate is 3 according to mass ratio with vaseline:1~6:1 Mixing, vaseline are 0.5 according to mass ratio with glycerine:1~3:1 mixing;
S3, by the sea-buckthorn/mix lubricant body and salt according to mass ratio it is 3:1~8:1 is uniformly mixed, and obtains sea-buckthorn salt Cream.
7. preparation method according to claim 6, which is characterized in that in the step S1, in the medicinal alcohol/water In mixture, the mass ratio of medicinal alcohol and water is 1:3~3:1;When using the fresh sea-buckthorn when, then the fresh sea-buckthorn with it is described The mass ratio of water in medicinal alcohol/water mixture is 1:3~1:8;When dry using the sea-buckthorn, then the sea-buckthorn is dry and institute The mass ratio for stating the water in medicinal alcohol/water mixture is 1:10~1:15.
8. preparation method according to claim 7, which is characterized in that in the step S1, extraction time be 12h~ 48h。
9. preparation method according to claim 6, which is characterized in that in the step S3, the grain size of the salt is small In 100 mesh.
CN201810862380.8A 2018-08-01 2018-08-01 Sea-buckthorn salt cream and preparation method thereof Pending CN108635383A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104783122A (en) * 2014-08-06 2015-07-22 中盐榆林盐化有限公司 Preparation method of sea-buckthorn health salt

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104783122A (en) * 2014-08-06 2015-07-22 中盐榆林盐化有限公司 Preparation method of sea-buckthorn health salt

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
宁海: "《新编妙药奇方》", 31 December 2006, 黑龙江朝鲜民族出版社 *
王绪前: "《中医食疗》", 31 October 2015, 中国中医药出版社 *
翟文龙: "《实用金版 家庭健康医疗百科全书》", 31 July 2015, 黑龙江科学技术出版社 *

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