CN108635287A - A kind of Dendrobidium huoshanness moisturizing emulsion and preparation method thereof - Google Patents
A kind of Dendrobidium huoshanness moisturizing emulsion and preparation method thereof Download PDFInfo
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- CN108635287A CN108635287A CN201810537615.6A CN201810537615A CN108635287A CN 108635287 A CN108635287 A CN 108635287A CN 201810537615 A CN201810537615 A CN 201810537615A CN 108635287 A CN108635287 A CN 108635287A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention discloses a kind of Dendrobidium huoshanness moisturizing emulsion and preparation method thereof, which contains Dendrobidium huoshanness extract, and the Dendrobidium huoshanness extract accounts for the 0.5 25% of moisturizing emulsion parts by weight.The moisturizing emulsion further includes the ingredient of following parts by weight：20 80 parts of vitamin es, 10 30 parts of camellia oils, 10 20 parts of cetostearyl alcohols, 15 parts of beeswaxs, 5 10 parts of polysorbate, 4 30 parts of olive oil, 20 80 parts of karayas, 1 20 parts of acetyl group sodium hyaluronates, 40 60 parts of pyrrolidone sodium carboxylates, 20 130 portions of mannitol, 24 parts of amino acid humectants, 12 parts of essence, 40 90 parts of glycerine, 13 parts of propylene glycol, 24 parts of sorbierites, 25 parts of xylitols, 58 parts of glycine betaines, 20 50 parts of deionized waters.The present invention have the effects that moisturizing, skin softening, it is crease-resistant, brighten, be salubrious, and have the function of antibacterial, anti-inflammatory effect, enhancing Cell-mediated Immunity, external application can resist dirt hide from, the infringement to skin such as bacterium.
Description
Technical field
The present invention relates to agricultural product deep processing technical field more particularly to a kind of Dendrobidium huoshanness moisturizing emulsion and its preparations
Method.
Background technology
Skin cell tissue's moisture is easy to be lost in, and lack of moisture can lead to xerosis cutis, dimness, generates scurf, wrinkle.It mends
Water moisturizing is the daily essential link of skin maintenance.Profession replenishing water and preserving moisture cosmetics, can deep layer, effective moisturizing,
Nourish skin of moistening.
Instantly, environmental pollution is serious, and the air of high pollution object content causes our skin different degrees of damage,
Therefore, people continue a kind of lotion that moistening effect is good and are protected to skin.Generally, due to the lipid and angle of skin
The presence of matter layer, hydrophilic molecule are difficult to be absorbed by organisms by skin barrier.Moisturizing emulsion maintenance in the prior art
Nourishes effect is to be improved.
Dendrobidium huoshanness is the fresh stem of orchid Dendrobidium huoshanness, and Dendrobidium huoshanness is《Anhui Province's prepared slices of Chinese crude drugs concocted specification》
Kind is included, dendrobium polysaccharide, dendrobine, dendramine, nobilonine, dendroxine, dendrine, 6-hydroxydendroxine are mainly contained
Equal bioactive substances, have precious health and medical value.It is comprehensive《Sheng Nong's herbal classic》、《Compendium of Materia Medica》、《Detailed outline picks up
It loses》With《It does not record》Discussion of the equal classical works to Dendrobidium huoshanness, primary efficacy are strong cloudy strengthening the essence, and clearing heat and promoting fluid can tonifying five zang organs
Consumptive disease, thick stomach, strong muscles and bones, arresting convulsion of calming the nerves, macrobiosis of making light of one's life by commiting suicide.Taoism regimen classical works《Taoist Scriptures》By Dendrobidium huoshanness, Tianshan Mountains
Saussurea involucrata, three double ginsengs, the hundred vicennial tubers of multiflower knotweed, cycle of sixty years Fu deserts (Poria cocos and desert cistanche), remote mountains ganoderma lucidum, seabed pearl and winter
The worm summer is careless and is known as Chinese nine big celestial grass, and Dendrobidium huoshanness ranks first.Dendrobidium huoshanness nature and flavor：It is sweet, it is slightly cold, enters stomach, kidney channel；Property category
It is clear and rich, there are benefit, bowl spares to have clearly in clear.
Also there is Dendrobidium huoshanness external efficacy, modern scientific research to show that Dendrobidium huoshanness is rich in polysaccharide, dendrobine, dissociates
Amino acid, vitamin (vitamin A, vitamin C, vitamin E), chlorophyll and various enzymes, not only can by oral absorption,
Dendrobidium huoshanness can also stop blooding, promote wound healing, can be used to repair damaged skin outside.
Dendrobidium huoshanness polysaccharide have the function of antibacterial, anti-inflammatory effect, enhancing Cell-mediated Immunity, external application can resist dirt hide from,
The infringement to skin such as bacterium；The external application of Dendrobidium huoshanness polysaccharide can stop blooding, and can promote the growth of skin fiber albumen, to promote
Into wound healing, damaged skin tissue is repaired.Free amino acid can provide skin immune function controlling, adjust moisture, soda acid, equilibrium oil
Fat has the antiallergic ability for improving sensitive, prevents the generation of wrinkle；Activate Skin Cell hepatocuprein peroxidating
The activity of object dispels the free radical of Skin Cell surplus, effective delay skin aging；The phagocytic function of activating macrophage increases
The toxin expelling of strong lymphatic system, function of detoxification effectively block infringement of the extraneous harmful substance to skin；Improve resisting skin allergy energy
Power, and excretion etc. is decomposed to internal harmful substance and aged cells.
Invention content
The purpose of the present invention is to provide a kind of Dendrobidium huoshanness moisturizing emulsions and preparation method thereof.
The technical problems to be solved by the invention are realized using following technical scheme：
A kind of Dendrobidium huoshanness moisturizing emulsion, containing Dendrobidium huoshanness extract, the Dendrobidium huoshanness extract accounts for moisturizing emulsion
The 0.5-25% of parts by weight.
Further, further include the ingredient of following parts by weight：20-80 parts of vitamin es, 10-30 parts of camellia oils, 10-20
Part cetostearyl alcohol, 1-5 parts of beeswaxs, 5-10 parts of polysorbate, 4-30 parts of olive oil, 20-80 parts of karayas, 1-20 parts of acetyl
Base sodium hyaluronate, 40-60 part pyrrolidone sodium carboxylate, 20-130 portions of mannitol, 2-4 parts of amino acid humectants, 1-2 parts of essence, 40-
90 parts of glycerine, 1-3 parts of propylene glycol, 2-4 parts of sorbierites, 2-5 parts of xylitols, 5-8 parts of glycine betaines, 20-50 parts of deionized waters.
Further, the Dendrobidium huoshanness extract is made by following steps：
(1) fresh Dendrobidium huoshanness is tapped, removing is gone mouldy insect bite part, after being rinsed well with clear water, it is put into 60%~
1~2min is impregnated in 80% ethanol solution, then removes the alcohol of surface attachment with aseptic water washing and is dried；
(2) Dendrobidium huoshanness that dries of sterilizing is sent into sterile operating room, is squeezed out Dendrobidium huoshanness Normal juice with juice extractor, with point
It disembarks and is centrifuged to squeezing the juice, Normal juice and the dregs of a decoction of Dendrobidium huoshanness are separated,
(3) take the Normal juice of step (2) through SP825 macroporous resin adsorptions, upper prop flow velocity is 2-4 times of resinite per hour
Product, upper column quantity are every liter of resin 10-30 liter；It is the elution of 30-90% ethanol waters with volume ratio, elution amount is SP825 macropores
3-8 times of resin；The SP825 macroporous resin columns are to measure SP825 macroreticular resin 100ml, are packed into diameter 2cm, long 50cm
Resin column, with volume ratio be 98% ethyl alcohol impregnate 5 hours, rinsed to no alcohol with pure water；
(4) dregs of a decoction for taking step (2) add 5~20 times of 5%~30% 0.5~1h of alcohol solution dipping of volume, then use
Flash extracter sudden strain of a muscle carries 1~3min, and sudden strain of a muscle carries 15000~20000rpm of rotating speed, filters, and the dregs of a decoction repeat sudden strain of a muscle and carry 1~2 time, merges
Sudden strain of a muscle carries gained filtrate, is concentrated into no alcohol taste；
(5) by step (3) the Dendrobidium huoshanness Normal juice that treated and step (4) treated concentration filtrate pour into ultrasonic wave
Dispersion machine carries out ultrasonic wave dispersion, and mixed liquor is obtained after dispersion；
(6) mixed liquor of step (5) is put into vacuum receiver and carries out vacuum outgas, temperature control in vacuum receiver
At 40~50 DEG C, vacuum degree is 0.08~0.12MPa, sloughs dissolved oxygen in mixed liquor；
(7) cellulase and pectase are added in mixed liquor after vacuum-degassing, dosage is respectively mix liquid measure 0.2
~0.3%, 0.02~0.04%, 45~55 DEG C of enzyme digestion reaction temperature, 2~3 hours reaction time；
(8) mixed liquor after digesting is filtered with pipelined filter, is removed floating outstanding object therein, is then used microporous membrane again
Filter micro-filtration again selects miillpore filter of the aperture at 0.2 μm~10 μm；
(9) finally use boxlike ultrafilter filter, ultrafiltration membrane aperture be 0.02 μm, remove mixed liquor in particle, colloid,
Bacterium, microorganism and larger molecular organics；
(10) the filtered mixed liquor of step (9) is concentrated and dried to get to Dendrobidium huoshanness extract.
Wherein, the ultrasonic power that ultrasonic wave disperses in the step (4) is 120-150W, and jitter time is 30-50 points
Clock, dispersion temperature are 20-25 DEG C.
The invention also discloses the preparation methods of the Dendrobidium huoshanness moisturizing emulsion, include the following steps：Dendrobidium huoshanness is carried
It takes object, vitamin e, camellia oil, cetostearyl alcohol, beeswax, polysorbate, olive oil, karaya that oil phase agitated kettle is added to add
Heat is heated to 85-95 DEG C of dissolving and obtains oil phase；By acetyl group sodium hyaluronate, pyrrolidone sodium carboxylate, mannitol, amino acid moisturizing
Agent, essence, glycerine, propylene glycol, sorbierite, xylitol, glycine betaine, deionized water, which are added in water phase agitated kettle to heat, goes out
Bacterium is heated to 85-100 DEG C of dissolving and obtains water phase；Water phase is slowly added to emulsify in oil phase and quickly stir, stirring is cooled to room
Temperature obtains the moisturizing emulsion after mixing.
Beneficial effects of the present invention：
Compared with prior art, the present invention amino acid humectant have moisturizing, skin softening, it is crease-resistant, the works such as brighten, be salubrious
With, can quickly penetrate into skin histology, make skin have gloss and salubrious wettability effect；Acetyl in acetyl group sodium hyaluronate molecule
Base is lipophilic group, and after being connected on hyaluronan molecule, performance of keeping humidity is more prominent；Tea polyphenols, saponin, antioxidant in camellia oil
Content is higher, using camellia oil as oil base, can improve dry rough skin, promote the healing of skin wound, scald, sunburn,
Skin can be enabled to distribute healthy and beautiful natural gloss；Karaya has good Native Gel characteristic, after water body disperses, colloid
Viscosity reduces, and can effectively avoid the volatilization of above-mentioned effective molecule, locks and supplies skin moisture, keep skin elasticity glossy；
Further, Dendrobidium huoshanness extract has antibacterial, anti-inflammatory effect, the work(for enhancing Cell-mediated Immunity in the present invention
Can, external application can resist dirt hide from, the infringement to skin such as bacterium, and damaged skin tissue can be repaired.In Dendrobidium huoshanness extract
Free amino acid skin immune function controlling can be provided, adjust moisture, soda acid, Sage Extract, there is the antiallergic for improving sensitive
Ability prevents the generation of wrinkle；The activity for activating Skin Cell hepatocuprein peroxide dispels Skin Cell surplus
Free radical, effective delay skin aging；The phagocytic function of activating macrophage, enhances the toxin expelling of lymphatic system, function of detoxification,
Effectively block infringement of the extraneous harmful substance to skin；Resisting skin allergy ability is improved, and thin to internal harmful substance and aging
Born of the same parents decompose excretion etc.；
The preparation process of Dendrobidium huoshanness extract is scientific and reasonable in the present invention, remains in Dendrobidium huoshanness to greatest extent
Effective active composition inevitably has a certain amount of air to dissolve in Dendrobidium huoshanness Normal juice, in air during squeezing the juice
Oxygen can cause the oxidizing brown stain of Dendrobidium huoshanness Normal juice, also result in the destruction of the nutritional ingredients such as vitamin C.In order to make Huoshan stone
For Normal juice of the dry measure used in former times after squeezing the juice from oxidizing brown stain, the Dendrobidium huoshanness Normal juice after squeezing the juice carries out vacuum outgas, sloughs Dendrobidium huoshanness
Dissolved oxygen in Normal juice can prevent the oxidation of active constituent and nutritional ingredient, Dendrobidium huoshanness Normal juice from containing centainly after vacuum outgas
The lymphatic temperament of amount, it is mucilagenous in the presence of causing Normal juice to be not easy to clarify and filter, fiber is added in the Dendrobidium huoshanness Normal juice squeezed out
Plain enzyme and pectase make soluble pectin hydrolysis, viscosity in Normal juice decline, and the suspended matter in Normal juice loses the protection of colloid, mistake
Filtration resistance power reduces, and the rate of filtration is accelerated, and Normal juice filtering is more prone to, and realizes the clarification of Dendrobidium huoshanness Normal juice height.
Specific implementation mode
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment 1
A kind of Dendrobidium huoshanness moisturizing emulsion, containing Dendrobidium huoshanness extract, the Dendrobidium huoshanness extract accounts for moisturizing emulsion
The 15% of parts by weight.
Further, further include the ingredient of following parts by weight：60 parts of vitamin es, 12 parts of camellia oils, 12 parts of cetearyl alcohols
Alcohol, 2 parts of beeswaxs, 6 parts of polysorbate, 22 parts of olive oil, 60 parts of karayas, 18 parts of acetyl group sodium hyaluronates, 45 parts of pyrrolidones
Carboxylic acid sodium, 120 portions of mannitol, 3 parts of amino acid humectants, 2 parts of essence, 70 parts of glycerine, 2 parts of propylene glycol, 4 parts of sorbierites, 4 parts of wood
Sugar alcohol, 8 parts of glycine betaines, 45 parts of deionized waters.
The preparation method of the Dendrobidium huoshanness moisturizing emulsion, includes the following steps：By Dendrobidium huoshanness extract, vitamin e, mountain
The heating of oil phase agitated kettle is added in tea oil, cetostearyl alcohol, beeswax, polysorbate, olive oil, karaya, is heated to 85-95 DEG C
Dissolving obtains oil phase；By acetyl group sodium hyaluronate, pyrrolidone sodium carboxylate, mannitol, amino acid humectant, essence, glycerine, the third two
Alcohol, sorbierite, xylitol, glycine betaine, deionized water are added in water phase agitated kettle and heat and sterilize, be heated to 85-100 DEG C it is molten
Solution obtains water phase；Water phase is slowly added to emulsify in oil phase and quickly stir, stirring is cooled to room temperature, and obtains institute after mixing
State moisturizing emulsion.
Embodiment 2
A kind of Dendrobidium huoshanness moisturizing emulsion, containing Dendrobidium huoshanness extract, the Dendrobidium huoshanness extract accounts for moisturizing emulsion
The 25% of parts by weight.
Further, further include the ingredient of following parts by weight：75 parts of vitamin es, 22 parts of camellia oils, 15 parts of cetearyl alcohols
Alcohol, 4 parts of beeswaxs, 8 parts of polysorbate, 22 parts of olive oil, 75 parts of karayas, 12 parts of acetyl group sodium hyaluronates, 42 parts of pyrrolidones
Carboxylic acid sodium, 80 portions of mannitol, 3 parts of amino acid humectants, 1 part of essence, 75 parts of glycerine, 1 part of propylene glycol, 4 parts of sorbierites, 4 parts of wood
Sugar alcohol, 6 parts of glycine betaines, 45 parts of deionized waters.
The preparation method of the Dendrobidium huoshanness moisturizing emulsion, includes the following steps：By Dendrobidium huoshanness extract, vitamin e, mountain
The heating of oil phase agitated kettle is added in tea oil, cetostearyl alcohol, beeswax, polysorbate, olive oil, karaya, is heated to 85-95 DEG C
Dissolving obtains oil phase；By acetyl group sodium hyaluronate, pyrrolidone sodium carboxylate, mannitol, amino acid humectant, essence, glycerine, the third two
Alcohol, sorbierite, xylitol, glycine betaine, deionized water are added in water phase agitated kettle and heat and sterilize, be heated to 85-100 DEG C it is molten
Solution obtains water phase；Water phase is slowly added to emulsify in oil phase and quickly stir, stirring is cooled to room temperature, and obtains institute after mixing
State moisturizing emulsion.
Embodiment 3
A kind of Dendrobidium huoshanness moisturizing emulsion, containing Dendrobidium huoshanness extract, the Dendrobidium huoshanness extract accounts for moisturizing emulsion
The 5% of parts by weight.
Further, further include the ingredient of following parts by weight：40 parts of vitamin es, 12 parts of camellia oils, 15 parts of cetearyl alcohols
Alcohol, 4 parts of beeswaxs, 8 parts of polysorbate, 22 parts of olive oil, 75 parts of karayas, 15 parts of acetyl group sodium hyaluronates, 55 parts of pyrrolidones
Carboxylic acid sodium, 115 portions of mannitol, 4 parts of amino acid humectants, 2 parts of essence, 75 parts of glycerine, 2 parts of propylene glycol, 3 parts of sorbierites, 2 parts of wood
Sugar alcohol, 7 parts of glycine betaines, 42 parts of deionized waters.
The preparation method of the Dendrobidium huoshanness moisturizing emulsion, includes the following steps：By Dendrobidium huoshanness extract, vitamin e, mountain
The heating of oil phase agitated kettle is added in tea oil, cetostearyl alcohol, beeswax, polysorbate, olive oil, karaya, is heated to 85-95 DEG C
Dissolving obtains oil phase；By acetyl group sodium hyaluronate, pyrrolidone sodium carboxylate, mannitol, amino acid humectant, essence, glycerine, the third two
Alcohol, sorbierite, xylitol, glycine betaine, deionized water are added in water phase agitated kettle and heat and sterilize, be heated to 85-100 DEG C it is molten
Solution obtains water phase；Water phase is slowly added to emulsify in oil phase and quickly stir, stirring is cooled to room temperature, and obtains institute after mixing
State moisturizing emulsion.
In above-described embodiment 1-2, Dendrobidium huoshanness extract is made by following steps：
(1) fresh Dendrobidium huoshanness is tapped, removing is gone mouldy insect bite part, after being rinsed well with clear water, it is put into 60%~
1~2min is impregnated in 80% ethanol solution, then removes the alcohol of surface attachment with aseptic water washing and is dried；
(2) Dendrobidium huoshanness that dries of sterilizing is sent into sterile operating room, is squeezed out Dendrobidium huoshanness Normal juice with juice extractor, with point
It disembarks and is centrifuged to squeezing the juice, Normal juice and the dregs of a decoction of Dendrobidium huoshanness are separated,
(3) take the Normal juice of step (2) through SP825 macroporous resin adsorptions, upper prop flow velocity is 2-4 times of resinite per hour
Product, upper column quantity are every liter of resin 10-30 liter；It is the elution of 30-90% ethanol waters with volume ratio, elution amount is SP825 macropores
3-8 times of resin；The SP825 macroporous resin columns are to measure SP825 macroreticular resin 100ml, are packed into diameter 2cm, long 50cm
Resin column, with volume ratio be 98% ethyl alcohol impregnate 5 hours, rinsed to no alcohol with pure water；
(4) dregs of a decoction for taking step (2) add 5~20 times of 5%~30% 0.5~1h of alcohol solution dipping of volume, then use
Flash extracter sudden strain of a muscle carries 1~3min, and sudden strain of a muscle carries 15000~20000rpm of rotating speed, filters, and the dregs of a decoction repeat sudden strain of a muscle and carry 1~2 time, merges
Sudden strain of a muscle carries gained filtrate, is concentrated into no alcohol taste；
(5) by step (3) the Dendrobidium huoshanness Normal juice that treated and step (4) treated concentration filtrate pour into ultrasonic wave
Dispersion machine carries out ultrasonic wave dispersion, and mixed liquor is obtained after dispersion；
(6) mixed liquor of step (5) is put into vacuum receiver and carries out vacuum outgas, temperature control in vacuum receiver
At 40~50 DEG C, vacuum degree is 0.08~0.12MPa, sloughs dissolved oxygen in mixed liquor；
(7) cellulase and pectase are added in mixed liquor after vacuum-degassing, dosage is respectively mix liquid measure 0.2
~0.3%, 0.02~0.04%, 45~55 DEG C of enzyme digestion reaction temperature, 2~3 hours reaction time；
(8) mixed liquor after digesting is filtered with pipelined filter, is removed floating outstanding object therein, is then used microporous membrane again
Filter micro-filtration again selects miillpore filter of the aperture at 0.2 μm~10 μm；
(9) finally use boxlike ultrafilter filter, ultrafiltration membrane aperture be 0.02 μm, remove mixed liquor in particle, colloid,
Bacterium, microorganism and larger molecular organics；
(10) the filtered mixed liquor of step (9) is concentrated and dried to get to Dendrobidium huoshanness extract.
Wherein, the ultrasonic power that ultrasonic wave disperses in the step (4) is 120-150W, and jitter time is 30-50 points
Clock, dispersion temperature are 20-25 DEG C.
Safety examination：
Test stone：《Cosmetics health specification》(version in 2007)
The present invention is through acute oral toxicity test, the results showed that the present invention is nontoxic.
The present invention passes through more skin irritant tests to skin irritation/corrosion test, the results showed that the present invention is several to skin
It is 0 stimulation.
The present invention is through skin Phototoxicity experiment, no photosensitized reaction.
The basic principles and main features of the present invention have been shown and described above.It should be understood by those skilled in the art that
The present invention is not limited to the above embodiments, and the above embodiments and description only illustrate the principle of the present invention,
Without departing from the spirit and scope, various changes and improvements may be made to the invention, these changes and improvements are all fallen
Enter in scope of the claimed invention.The scope of the present invention is defined by the appended claims and its equivalents.
Claims (5)
1. a kind of Dendrobidium huoshanness moisturizing emulsion, which is characterized in that containing Dendrobidium huoshanness extract, the Dendrobidium huoshanness extract accounts for
The 0.5-25% of moisturizing emulsion parts by weight.
2. a kind of Dendrobidium huoshanness moisturizing emulsion according to claim 1, which is characterized in that further include following parts by weight
Ingredient：20-80 parts of vitamin es, 10-30 parts of camellia oils, 10-20 parts of cetostearyl alcohols, 1-5 parts of beeswaxs, 5-10 parts of polysorbates
Ester, 4-30 part olive oil, 20-80 parts of karayas, 1-20 parts of acetyl group sodium hyaluronates, 40-60 parts of pyrrolidone sodium carboxylates, 20-130
Part mannitol, 2-4 parts of amino acid humectants, 1-2 parts of essence, 40-90 parts of glycerine, 1-3 parts of propylene glycol, 2-4 parts of sorbierites, 2-5
Part xylitol, 5-8 parts of glycine betaines, 20-50 parts of deionized waters.
3. a kind of Dendrobidium huoshanness moisturizing emulsion according to claim 1, which is characterized in that the Dendrobidium huoshanness extract is logical
Following steps are crossed to be made：
(1) fresh Dendrobidium huoshanness is tapped, insect bite part of going mouldy is removed, after being rinsed well with clear water, is put into 60%~80% second
Then 1~2min of alcohol solution for soaking removes the alcohol of surface attachment with aseptic water washing and dries；
(2) Dendrobidium huoshanness that dries of sterilizing is sent into sterile operating room, is squeezed out Dendrobidium huoshanness Normal juice with juice extractor, uses seperator
It is centrifuged to squeezing the juice, Normal juice and the dregs of a decoction of Dendrobidium huoshanness is separated,
(3) take the Normal juice of step (2) through SP825 macroporous resin adsorptions, upper prop flow velocity is 2-4 times of resin volume per hour, on
Column amount is every liter of resin 10-30 liter；It is the elution of 30-90% ethanol waters with volume ratio, elution amount is SP825 macroreticular resins
3-8 times；The SP825 macroporous resin columns are to measure SP825 macroreticular resin 100ml, are packed into the resin of diameter 2cm, long 50cm
Column is that 98% ethyl alcohol impregnates 5 hours with volume ratio, is rinsed to no alcohol with pure water；
(4) dregs of a decoction for taking step (2) add 5~20 times of 5%~30% 0.5~1h of alcohol solution dipping of volume, then with flash
Extractor sudden strain of a muscle carries 1~3min, and sudden strain of a muscle carries 15000~20000rpm of rotating speed, filters, and the dregs of a decoction repeat sudden strain of a muscle and carry 1~2 time, merges sudden strain of a muscle and carries
Gained filtrate is concentrated into no alcohol taste；
(5) by step (3) the Dendrobidium huoshanness Normal juice that treated and step (4) treated concentration filtrate pour into ultrasonic wave dispersion
Machine carries out ultrasonic wave dispersion, and mixed liquor is obtained after dispersion；
(6) mixed liquor of step (5) is put into vacuum receiver and carries out vacuum outgas, temperature control is 40 in vacuum receiver
~50 DEG C, vacuum degree is 0.08~0.12MPa, sloughs dissolved oxygen in mixed liquor；
(7) be added cellulase and pectase in mixed liquor after vacuum-degassing, dosage be respectively mix liquid measure 0.2~
0.3%, 0.02~0.04%, 45~55 DEG C of enzyme digestion reaction temperature, 2~3 hours reaction time；
(8) mixed liquor after digesting is filtered with pipelined filter, is removed floating outstanding object therein, is then used microporous membrane filtration again
Device micro-filtration again selects miillpore filter of the aperture at 0.2 μm~10 μm；
(9) finally boxlike ultrafilter is used to filter, ultrafiltration membrane aperture is 0.02 μm, removes particle in mixed liquor, colloid, thin
Bacterium, microorganism and larger molecular organics；
(10) the filtered mixed liquor of step (9) is concentrated and dried to get to Dendrobidium huoshanness extract.
4. a kind of Dendrobidium huoshanness moisturizing emulsion according to claim 3, which is characterized in that ultrasonic wave in the step (4)
The ultrasonic power of dispersion is 120-150W, and jitter time is 30-50 minutes, and dispersion temperature is 20-25 DEG C.
5. the preparation method of Dendrobidium huoshanness moisturizing emulsion as described in claims 1 or 2 any one, which is characterized in that including with
Lower step：By Dendrobidium huoshanness extract, vitamin e, camellia oil, cetostearyl alcohol, beeswax, polysorbate, olive oil, Chinese parasol tree
The heating of oil phase agitated kettle is added in glue, is heated to 85-95 DEG C of dissolving and obtains oil phase；By acetyl group sodium hyaluronate, pyrrolidone sodium carboxylate,
Mannitol, amino acid humectant, essence, glycerine, propylene glycol, sorbierite, xylitol, glycine betaine, deionized water are added water phase and stir
It mixes heating in pot to sterilize, is heated to 85-100 DEG C of dissolving and obtains water phase；Water phase is slowly added in oil phase emulsification and quick
Stirring, stirring are cooled to room temperature, and obtain the moisturizing emulsion after mixing.
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Cited By (2)
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| CN113975199A (en) * | 2021-11-03 | 2022-01-28 | 胡昌山 | Skin-firming wrinkle-removing anti-aging essence and preparation process thereof |
| CN114451509A (en) * | 2021-06-04 | 2022-05-10 | 泰州医药城国科化物生物医药科技有限公司 | Preparation method and application of ginseng extract |
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| CN102008654A (en) * | 2010-12-12 | 2011-04-13 | 杨军 | Method for manufacturing dendrobium officinale fresh juice stock solution |
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| CN103705435A (en) * | 2014-01-01 | 2014-04-09 | 来凤县三丰时代农业有限公司 | Selenium-rich sweet potato skin moisturizer |
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| CN102008654A (en) * | 2010-12-12 | 2011-04-13 | 杨军 | Method for manufacturing dendrobium officinale fresh juice stock solution |
| WO2013040395A2 (en) * | 2011-09-14 | 2013-03-21 | Nefeli Corp. | Herbal skin care composition |
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| CN114451509A (en) * | 2021-06-04 | 2022-05-10 | 泰州医药城国科化物生物医药科技有限公司 | Preparation method and application of ginseng extract |
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| CN113975199B (en) * | 2021-11-03 | 2024-04-16 | 胡昌山 | Preparation process of skin tightening, wrinkle removing and anti-aging essence |
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