CN108635271A - A kind of beauty method for dispelling chorioplaque - Google Patents

A kind of beauty method for dispelling chorioplaque Download PDF

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Publication number
CN108635271A
CN108635271A CN201810732907.5A CN201810732907A CN108635271A CN 108635271 A CN108635271 A CN 108635271A CN 201810732907 A CN201810732907 A CN 201810732907A CN 108635271 A CN108635271 A CN 108635271A
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melanin
extract
skin
chorioplaque
method described
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盛小笑
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/067Radiation therapy using light using laser light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/83Electrophoresis; Electrodes; Electrolytic phenomena

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a kind of beauty method for dispelling chorioplaque, the method includes:A, melanin condenses:Traditional Chinese medicinal poultice is applied in the skin surface for forming chorioplaque, skin surface is made to form melanin condensation spot;The ingredient of the Traditional Chinese medicinal poultice includes Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A;B, melanin is desalinated:The surface that spot is condensed in melanin applies hydroxyl aqueous acid;C, melanin is removed:Laser elimination is carried out to the melanin condensation spot that do not desalinate using laser, then the antibacterial skin liquid of sprinkling addition L-Ascorbic Acid L-O-Phosphate and fibroin albumen.The present invention does not use high new instrument at high price and complicated for operation, function is condensed by Chinese medicine and the unique melanin of cell level, carry out condensation melanin, then desalinated and removed, than tradition chorioplaque, to dispel method simple for operation, short time training can smooth operation, reduce induce melanin explosion time, as far as possible control pigment reflux.

Description

A kind of beauty method for dispelling chorioplaque
Technical field
The present invention relates to beautifying technique fields, and in particular to a kind of beauty method for dispelling chorioplaque.
Background technology
Melanin is generated in melanosome, and substrate tyrosine is in rate-limiting enzyme --- the catalysis of tyrosinase (TYR) is made After becoming DOPA quinone under, carries out a series of automatic oxidation reaction and connect reaction, ultimately generate pheomelanin, and pheomelanin Red is presented under normal circumstances, melanin melanocortin receptor 1 (MClR) expression is normal, then pheomelanin synthesis can be suppressed; When MClR mutates, pheomelanin will express, and make the partially red of the colour of skin and DOPA quinone can form colourless dopachrome, One side dopachrome ultimately forms black eumelanin under the action of without enzyme by a series of reaction, on the other hand it It can be ultimately formed under the catalytic action of tyrosinase related protein1 (TRP2) and tyrosinase-related protein 1 (TRPl) brown true Melanocyte.Black is presented in wherein black eumelanin, and grey is presented when content is low;Brown is presented in brown eumelanin, is showed when content is low For brown.The height of two kinds of eumelanin contents forms different colour of skin in addition, two kinds of pigments of eumelanin and pheomelanin in skin Belong to the melanin of macromolecular form, it is not soluble in water, exist in powder form;And other pigment moleculars or intermediate product belong to The melanin of low molecule form, it is water-soluble.
Chorioplaque (Dermal spots) is the pigmentation or pigmentation and lead mercury toxin positioned at dermis of skin position Residue mixing.Chorioplaque is typically distributed across facial two cheeks, also has minority to grow above and below temple, there is dotted and sheet. The generation of chorioplaque is used under normal circumstances to the harmful nti-freckle product of skin, such as leaded mercury, quinhydrones, high concentration tartaric acid product Skin after red, swollen inflammatory reaction, then can will be peeled, expose fresh first after wound process by prodigious injury, skin afterwards Tender basal layer cell.This method destroys the eubolism of epidermis, and the resistance of skin is made to be weakened significantly, when skin is thin After born of the same parents lose immune function, human body will secrete a large amount of black spots to protect impaired cell, therefore color spot can be made more tight Weight, up to there is intractable blackspot after half a year in 70-80% patient.
The Chinese patent literature of Publication No. CN102755639A discloses a kind of drug for dispelling chorioplaque, it is characterized in that It is made of medicine for oral administration and externally used paste two parts, the externally used paste is by carbolic acid, Da Kening, peppermint, dexamethasone and collagen Albumen is formulated, and the medicine for oral administration includes decoction and pill, and the decoction is that raw material presses biography by fructus corni, safflower, Chinese yam, Poria cocos Decoction made of system decocting method, the pill are Radix Et Rhizoma Rhei et Eupolyphaga Seu Steleophaga Pilulae.
The Chinese patent literature of Publication No. CN107551143A discloses a kind of chorioplaque deep layer pumping color technology, it includes The preparation method for the medicament and the medicament that the raw material of following mass fraction (100 parts of meters) is prepared:Wherein, the medicament Including 3~8 parts of honey, 5~12 parts of egg white, 10~20 parts of almond, 10~20 parts of Rhizoma Chuanxiong, 1~5 part of vitamin, the bletilla striata 15~ 20 parts, 5~10 parts of the root of Dahurain angelica, 5~8 parts of lucid asparagus, 10~25 parts of burdock, 5~10 parts of Poria cocos, 1~2 part of alcohol;The medicament Preparation method includes:The first step takes almond, the root of Dahurain angelica, lucid asparagus, burdock to mix and crushes, and is heated to boiling;Second step takes river Rhizome of chuanxiong, the bletilla striata, Poria cocos, which are put into thermostatted water, to be impregnated;Third walks, and the first step, second step are mixed into mixed liquor, above-mentioned quality is added The honey of number, egg white stirring are spare;Vitamin alcohol is added in 4th step;5th step, is made plaster.
Or the prior art is wanted to make the melanin outburst in chorioplaque right to surface by instrument or by chemicals Disposable afterwards to solve, idea is very good, but melanin induces its outburst to need the time, is also required to when pigment flows back big The manpower, material resources and financial resources of amount go to solve, and get half the result with twice the effort.
Invention content
The purpose of the present invention is to provide a kind of beauty method for dispelling chorioplaque, method of the invention dispels chorioplaque Effect is good, and required time is short.
To achieve the above object, the present invention provides a kind of beauty method for dispelling chorioplaque, the method includes:
A, melanin condenses:Traditional Chinese medicinal poultice is applied in the skin surface for forming chorioplaque, so that skin surface is formed melanin solidifying Maculose;The ingredient of the Traditional Chinese medicinal poultice includes Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A, The Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A weight ratio be 100:(2-8):(1- 5):(0.1-1);
B, melanin is desalinated:In the surface coating hydroxyl aqueous acid of melanin condensation spot, the hydroxyl aqueous acid Carboxylic acid containing 0.1-0.3 weight %;
C, melanin is removed:Laser elimination is carried out to the melanin condensation spot that do not desalinate using 1064nm laser, is then sprayed Spill the antibacterial skin liquid of addition 0.1-3 weight % L-Ascorbic Acid L-O-Phosphates and 0.1-0.4 weight % fibroin albumens.
Optionally, the preparation process of the Grape Skin ethanol extract includes:
It is crushed after Grape Skin is cleaned using ethyl alcohol;
Grape Skin is according to weight ratio 1 after crushing:Ultrasonic homogeneous after ethyl alcohol is added in (5-10);
It is filtered after homogenizing fluid is stood 2-120h, gained filtrate is rotated to volume and reduced to 1/5-1/2.
Optionally, the preparation process of the black bearberry leaf extract includes:
It is crushed after taking fresh picking uva ursi to wash with water;
Uva ursi after crushing is extracted in 50-80 DEG C of water, is then filtered, gained filtrate is dried.
Optionally, the preparation process of the angelica extract includes:
Radix Angelicae Sinensis is crushed into immersion 1-12 hours in water;
Soak and Radix Angelicae Sinensis are extracted in electric pulse extraction tank together, gained extracting solution carries out room temperature revolving.
Optionally, the carboxylic acid is malic acid or tartaric acid.
Optionally, the condition of the laser elimination is:Energy 4.2J/cm2, frequency 5Hz, hot spot 3.5mm, duration 3- 8 minutes.
Optionally, the antibacterial skin liquid includes Honegsukle flower P.E, dandelion extract and mint extract.
Optionally, the weight ratio of the Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A It is 100:(3-6):(2-4):(0.3-0.5).
Optionally, the time for applying Traditional Chinese medicinal poultice is 30min-3h, and the time of coating hydroxyl aqueous acid is 5-30min.
The invention has the advantages that:
The present invention does not use high new instrument at high price and complicated for operation, leans on the unique black of Chinese medicine and cell level Element condensation function, carries out condensation melanin, is then desalinated and removed, simple, simplicity that operation than traditional chorioplaque dispels method It is easy to learn, the short time training can smooth operation, reduce induce melanin explosion time, as far as possible control pigment reflux.
Description of the drawings
Fig. 1 is the photo of skin before the non-beauty of patient in embodiment (black splotch is chorioplaque).
Fig. 2 is the photo that patient carries out skin after melanin condensation in embodiment (black splotch is chorioplaque).
Fig. 3 is the photo of skin after patient's beauty in embodiment.
Specific implementation mode
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
The present invention provides a kind of beauty method for dispelling chorioplaque, the method includes:
A, melanin condenses:Traditional Chinese medicinal poultice is applied in the skin surface for forming chorioplaque, so that skin surface is formed melanin solidifying Maculose;The ingredient of the Traditional Chinese medicinal poultice includes Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A, The Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A weight ratio be 100:(2-8):(1- 5):(0.1-1), preferably 100:(3-6):(2-4):(0.3-0.5);The time for applying Traditional Chinese medicinal poultice is 30min-3h, applies hydroxyl The time of base aqueous acid is 5-30min.
B, melanin is desalinated:In the surface coating hydroxyl aqueous acid of melanin condensation spot, the hydroxyl aqueous acid Carboxylic acid containing 0.1-0.3 weight %;
C, melanin is removed:Laser elimination is carried out to the melanin condensation spot that do not desalinate using 1064nm laser, is then sprayed Spill the antibacterial skin liquid of addition 0.1-3 weight % L-Ascorbic Acid L-O-Phosphates and 0.1-0.4 weight % fibroin albumens.
In the present invention, containing the ingredient for making melanin condense in Grape Skin ethanol extract, the black of dermal sites can be made Pigment condenses, and in order to the desalination and stripping of subsequent dark element, the preparation process of the Grape Skin ethanol extract may include: It is crushed after Grape Skin is cleaned using ethyl alcohol;Grape Skin is according to weight ratio 1 after crushing:Ultrasound is equal after ethyl alcohol is added in (5-10) Matter;It is filtered after homogenizing fluid is stood 2-120h, gained filtrate is rotated to volume and reduced to 1/5-1/2.
In the present invention, black bearberry leaf extract and angelica extract can inhibit the activity of TYR enzyme, block melanin life At to make melanin fade area not will produce new melanin, vitamin A can promote the metabolism of skin, accelerate melanin Aggregation.The preparation process of the black bearberry leaf extract may include:It is crushed after taking fresh picking uva ursi to wash with water;It will crush Uva ursi extracts in 50-80 DEG C of water afterwards, then filters, and gained filtrate is dried.The system of the angelica extract May include for step:Radix Angelicae Sinensis is crushed into immersion 1-12 hours in water;Soak and Radix Angelicae Sinensis are carried in electric pulse together It takes in slot and extracts, gained extracting solution carries out room temperature revolving.
In the present invention, for carboxylic acid for being destroyed to dermis of skin part cell, the skin after making melanin desalinate can Further to bleach, for example, the carboxylic acid can be malic acid or tartaric acid.
For the spot of melanin aggregation, is acted on by the way of desalination less, since the number of spot is few, at this time may be used To be eliminated using laser fixed point, the condition that the laser is eliminated can be:Energy 4.2J/cm2, frequency 5Hz, hot spot 3.5mm are held Continuous time 3-8 minute.
In the present invention, antibacterial skin liquid be it is well-known to those skilled in the art, for laser eliminate after skin into Row sterilization restores, and the antibacterial skin liquid may include Honegsukle flower P.E, dandelion extract and mint extract.Vitamin C phosphates magnesium and fibroin albumen can promote collagen growth, to keep newly-generated skin more smooth.
It is further illustrated the present invention below by embodiment, but it is not thereby limiting the invention.
Embodiment
Patient, model so-and-so, 43 years old, on the face two cheeks have chorioplaque, local pictures are as shown in Figure 1, method using the present invention Carry out beauty.
It is prepared by Grape Skin ethanol extract:It cleans to no grape pulp, new fresh grape fleshing and seed by grape using ethyl alcohol Skin is shredded using scissors to 1cm or less.It takes the Grape Skin after 15 grams of crushing to be mixed with 100 grams of ethyl alcohol and then uses ultrasonic machine In under the frequency of 15000Hz carry out ultrasound 15 seconds, obtain homogenizing fluid be put into shady place capping preservative film carry out stand 24 hours, Then Grape Skin is filtered off, then revolving filtrate obtains Grape Skin ethanol extract to the half of original volume at room temperature.
The preparation process of black bearberry leaf extract includes:Fresh uva ursi is cleaned using water to no dust, is then cut After being crushed using drug ramming pot after broken, uva ursi is put into 60 DEG C of water, impregnates 5 minutes, then filter, by filtrate under stiring It is dried, obtains black bearberry leaf extract.
The preparation process of angelica extract includes:Radix Angelicae Sinensis is crushed using pulverizer, is then steeped 3 in the water of room temperature Hour, it then carries out extracting in electric pulse extraction tank, filtering gained extracting solution is rotated in room temperature, obtains angelica extract.
100 grams of Grape Skin ethanol extracts, 3 grams of black bearberry leaf extracts, 2 grams of angelica extracts and 0.3 gram of vitamin A are mixed Conjunction stirs evenly, and then smears on non-woven fabrics after sterilization, obtains Traditional Chinese medicinal poultice.Traditional Chinese medicinal poultice is applied in patient's two cheek on the face On, patient is then sticked on the face using medical adhesive tape, is kept for 2 hours, patient is now in lying status.
After 2 hours, Traditional Chinese medicinal poultice is removed on the face from patient, at this time as shown in Figure 2, it can be seen that patient originally divided on the face Scattered chorioplaque is coagulated together, to form the chorioplaque and condensation spot of desalination.Patient's cheek is carried out using cotton ball soaked in alcohol Alcohol volatilization is waited for after disinfection, is then used cotton swab to smear the aqueous tartaric acid solution of 0.3 weight % on the face in patient, is kept for 15 points Clock.It can be seen that desalination chorioplaque is further desalinated.
Using 1064nm lasers in energy 4.2J/cm2, condensation spot is carried out under conditions of frequency 5Hz, hot spot 3.5mm Emphasis is removed, and the time can be maintained at 3-8 minutes or so according to each spot of spot size.
After spot is removed, fragrant female antibacterial skin liquid is sprayed in wound surface, fragrant mother's antibacterial skin liquid is added to 0.2 Then the fibroin albumen of weight % L-Ascorbic Acid L-O-Phosphates and 0.3 weight % is stained with bandage on wound, tears after 6 hours Bandage, skin is as shown in figure 3, chorioplaque substantially eliminates and desalinates.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore, These modifications or improvements without departing from theon the basis of the spirit of the present invention belong to the scope of protection of present invention.

Claims (9)

1. a kind of beauty method for dispelling chorioplaque, which is characterized in that the method includes:
A, melanin condenses:Traditional Chinese medicinal poultice is applied in the skin surface for forming chorioplaque, skin surface is made to form melanin condensation spot; The ingredient of the Traditional Chinese medicinal poultice includes Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A, described Grape Skin ethanol extract, black bearberry leaf extract, angelica extract and vitamin A weight ratio be 100:(2-8):(1-5): (0.1-1);
B, melanin is desalinated:The surface that spot is condensed in melanin applies hydroxyl aqueous acid, contains in the hydroxyl aqueous acid The carboxylic acid of 0.1-0.3 weight %;
C, melanin is removed:Laser elimination is carried out to the melanin condensation spot that do not desalinate using 1064nm laser, then sprinkling adds Add the antibacterial skin liquid of 0.1-3 weight % L-Ascorbic Acid L-O-Phosphates and 0.1-0.4 weight % fibroin albumens.
2. according to the method described in claim 1, it is characterized in that, the preparation process of the Grape Skin ethanol extract includes:
It is crushed after Grape Skin is cleaned using ethyl alcohol;
Grape Skin is according to weight ratio 1 after crushing:Ultrasonic homogeneous after ethyl alcohol is added in (5-10);
It is filtered after homogenizing fluid is stood 2-120h, gained filtrate is rotated to volume and reduced to 1/5-1/2.
3. according to the method described in claim 1, it is characterized in that, the preparation process of the black bearberry leaf extract includes:
It is crushed after taking fresh picking uva ursi to wash with water;
Uva ursi after crushing is extracted in 50-80 DEG C of water, is then filtered, gained filtrate is dried.
4. according to the method described in claim 1, it is characterized in that, the preparation process of the angelica extract includes:
Radix Angelicae Sinensis is crushed into immersion 1-12 hours in water;
Soak and Radix Angelicae Sinensis are extracted in electric pulse extraction tank together, gained extracting solution carries out room temperature revolving.
5. according to the method described in claim 1, it is characterized in that, the carboxylic acid is malic acid or tartaric acid.
6. according to the method described in claim 1, it is characterized in that, the condition that the laser is eliminated is:Energy 4.2J/cm2, frequency Rate 5Hz, hot spot 3.5mm, duration 3-8 minute.
7. according to the method described in claim 1, it is characterized in that, the antibacterial skin liquid includes Honegsukle flower P.E, Pu Gong English extract and mint extract.
8. according to the method described in claim 1, it is characterized in that, the Grape Skin ethanol extract, black bearberry leaf extract, when It is 100 to return the weight ratio of extract and vitamin A:(3-6):(2-4):(0.3-0.5).
9. according to the method described in claim 1, it is characterized in that, apply Traditional Chinese medicinal poultice time be 30min-3h, apply hydroxyl The time of aqueous acid is 5-30min.
CN201810732907.5A 2018-07-05 2018-07-05 A kind of beauty method for dispelling chorioplaque Pending CN108635271A (en)

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Title
(美)德拉洛斯主编: "功能性化妆品", 人民军医出版社, pages: 106 *

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