CN108603877A - 使用多基质的分析物检测 - Google Patents

使用多基质的分析物检测 Download PDF

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Publication number
CN108603877A
CN108603877A CN201680070554.6A CN201680070554A CN108603877A CN 108603877 A CN108603877 A CN 108603877A CN 201680070554 A CN201680070554 A CN 201680070554A CN 108603877 A CN108603877 A CN 108603877A
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CN
China
Prior art keywords
reagent
analyte
peptide
binding
bead
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201680070554.6A
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English (en)
Chinese (zh)
Inventor
安东尼·詹姆斯·希恩
迈克尔·弗朗西斯·克劳奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TGR Bioscience Pty Ltd
Original Assignee
TGR Bioscience Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TGR Bioscience Pty Ltd filed Critical TGR Bioscience Pty Ltd
Publication of CN108603877A publication Critical patent/CN108603877A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201680070554.6A 2015-10-02 2016-09-30 使用多基质的分析物检测 Pending CN108603877A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562236676P 2015-10-02 2015-10-02
US62/236,676 2015-10-02
US201562237522P 2015-10-05 2015-10-05
US62/237,522 2015-10-05
PCT/IB2016/001981 WO2017068431A1 (en) 2015-10-02 2016-09-30 Analyte detection with multiple substrates

Publications (1)

Publication Number Publication Date
CN108603877A true CN108603877A (zh) 2018-09-28

Family

ID=58446765

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680070554.6A Pending CN108603877A (zh) 2015-10-02 2016-09-30 使用多基质的分析物检测

Country Status (9)

Country Link
US (3) US20180275121A1 (https=)
EP (1) EP3356822B1 (https=)
JP (1) JP2018533017A (https=)
CN (1) CN108603877A (https=)
AU (1) AU2016341539A1 (https=)
CA (1) CA3000584A1 (https=)
HK (1) HK1254374A1 (https=)
MX (1) MX2018004029A (https=)
WO (1) WO2017068431A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057347A1 (en) 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
WO2021070218A1 (ja) * 2019-10-07 2021-04-15 ナノティス株式会社 試料中の被検出物質を検出する方法
TWI832129B (zh) * 2020-12-28 2024-02-11 財團法人工業技術研究院 多重分析物的檢測方法
JP2024538620A (ja) * 2021-09-30 2024-10-23 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 抗ｓａｒｓ－ｃｏｖ－２抗体の二重イムノアッセイのための組成物、キット、および方法
WO2025235476A2 (en) * 2024-05-06 2025-11-13 Beckman Coulter, Inc. Calibration independent immunoassay systems and methods for comparative analyte detection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232391A1 (en) * 2002-03-21 2003-12-18 Prescott John C. Identification of kinase inhibitors
WO2010095033A1 (en) * 2009-02-20 2010-08-26 Perkinelmer Biosignal, Inc. Multiplex assay methods and compositions
WO2012129611A1 (en) * 2011-03-31 2012-10-04 Tgr Biosciences Pty Ltd Detection of multiple analytes
CN104897652A (zh) * 2015-03-19 2015-09-09 杭州金溪生物技术有限公司 一步均相化学发光法进行小分子检测的方法及所用微粒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995006877A1 (en) 1993-09-03 1995-03-09 Behringwerke Ag Fluorescent oxygen channeling immunoassays
US20030232394A1 (en) 2002-06-12 2003-12-18 Aventis Pharma Deutschland Gmbh High throughput screening method and assay system for determining the interaction between C-reactive protein and components binding to it
DE10226011A1 (de) * 2002-06-12 2004-01-08 Aventis Pharma Deutschland Gmbh HTS-fähiges Verfahren und Testsystem zur Ermittlung der Wechselwirkung zwischen c-reaktivem Protein und an C-reaktives Protein bindenden Komponenten
AU2008328726B2 (en) * 2007-11-30 2014-06-12 Glaxo Group Limited Antigen-binding constructs
JP5770161B2 (ja) * 2009-04-06 2015-08-26 ノヴォ ノルディスク アー／エス 血小板への第ｖｉｉｉ因子タンパク質の標的送達
WO2011057347A1 (en) 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
WO2012129610A1 (en) * 2011-03-31 2012-10-04 Tgr Biosciences Pty Ltd One-step immunoassay detection of analytes
GB201403875D0 (en) * 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
WO2016029220A1 (en) * 2014-08-22 2016-02-25 Nectagen, Inc. Affinity proteins and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232391A1 (en) * 2002-03-21 2003-12-18 Prescott John C. Identification of kinase inhibitors
WO2010095033A1 (en) * 2009-02-20 2010-08-26 Perkinelmer Biosignal, Inc. Multiplex assay methods and compositions
WO2012129611A1 (en) * 2011-03-31 2012-10-04 Tgr Biosciences Pty Ltd Detection of multiple analytes
CN104897652A (zh) * 2015-03-19 2015-09-09 杭州金溪生物技术有限公司 一步均相化学发光法进行小分子检测的方法及所用微粒

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
PERKINELMER: "A Practical Guide to working with AlphaScreen", 《PERKINELMER》 *
PERKINELMER: "Principles of AlphaScreen：Amplified Luminescent Proximity Homogeneous Assay，", 《PERKINELMER BROCHURE》 *
PERKINELMER: "Taking protein phosphorylation measurement one step further", 《PERKINELMER BROCHURE》 *
RICHARD M.EGLEN等: "The use of AlphaScreen Technology in HTS:Current Status", 《CURRENT CHEMICAL GENOMICS》 *

Also Published As

Publication number Publication date
HK1254374A1 (zh) 2019-07-19
MX2018004029A (es) 2018-07-06
US20170097339A1 (en) 2017-04-06
EP3356822A1 (en) 2018-08-08
US20180136202A1 (en) 2018-05-17
CA3000584A1 (en) 2017-04-27
JP2018533017A (ja) 2018-11-08
US20180275121A1 (en) 2018-09-27
AU2016341539A1 (en) 2018-04-26
EP3356822B1 (en) 2021-10-27
WO2017068431A1 (en) 2017-04-27
EP3356822A4 (en) 2019-07-03

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