CN108578613A - Treat the drug and preparation method thereof of fibroid - Google Patents

Abstract

The present invention provides a kind of drug for treating fibroid, and the bulk pharmaceutical chemicals by its active ingredient as unit of parts by weight, is made are：Saltcake, cassia twig, seaweed, Radix Salviae Miltiorrhizae, Snakegourd Fruit, tangerine seed, hawthorn, the root of bidentate achyranthes, dragon's blood, fritillaria, semen brassicae, trigone, coix seed, Prunella vulgaris, peach kernel, Southern Star, radix paeoniae rubra, Radix Glycyrrhizae, Pollen Typhae, excrementum pteropi, frankincense, myrrh, glutinous rehmannia, radix bupleuri.The present invention provides a kind of drugs for treating fibroid, therapeutic effect is good, it has no toxic side effect, the symptoms such as qi depression to blood stasis, phlegm wet stasis, dampness and heat stasis, kidney deficiency blood stasis can be fundamentally treated, the organism endocrine of patient can be improved, enhance the constitution of patients with uterine myoma, it is very big to the recurrence and transfer benefit that prevent fibroid, Clinical Practice effect is very good, and convenient to take, easy to spread.

Description

Treat the drug and preparation method thereof of fibroid

One, technical field：

The invention belongs to the field of Chinese medicines, and in particular to a kind of drug and preparation method thereof for treating fibroid.

Two, background technology：

Fibroid is one of most common tumour in the most common type benign tumour and human body in female sex organ. Fibroid belongs to the disease of " a lump in the abdomen causing distension and pain ", mostly not smooth due to qi and blood, caused by qi and blood stagnation vessels of the uterus.The whole world has 3.2 hundred million People, China have nearly 1,500,000 women because fibroid is cut off uterus every year；The method for the treatment of fibroid has Western medicine to control at present It treats, traditional abdominal and Minimally Invasive Surgery, intervention are performed the operation.Wherein：A, western medical treatment uses sex hormone medicine on clinical application Object although can inhibit the growth of myomata in short term, widely applies hormone therapy, to body for a long time to reduce androgen levels by force Body burden is big, easily causes metabolism and water-electrolyte metabolism to be upset, endocrine disorder is caused to aggravate, and long-term use side effect is very big, Severe patient can lead to lesion.B, Tradtional laparotomy：Clean cut refers to cutting the edge of a knife in patient abdomen, and by hysterotomy, Myomata removes, some even need to cut off entire uterus, then by wound suture, operating time is long, restores slow, seriously affects normal Work, and postoperative abdominal can scar, influence beauty, be more likely to bring the complication such as abdominal cavity infection, pelvic adhesion, sternly Severe one can lead to infertility, and there is no myomata growing environment is improved, easily recur.C, Minimally Invasive Surgery, intervention operation：It is so-called Minimally invasive is also one kind of operation in fact, and only surface skin wound is smaller, but still needs to operate in abdominal cavity, and doctor Uterus can not be touched so that the small myomata of some volumes is at fish that has escape the net, and to hidden danger is left in the future, recurrence rate is high, right Wound is brought again in uterus.

Currently on the market treatment fibroid Chinese patent drug kind it is very few, cannot satisfy social needs, on the other hand these The effect of old kind drug is not still especially desirable, there is the traditional Chinese patent medicine that curative effect yet-to-be developed further increases.

Invention content：

The technical problem to be solved by the present invention is to：A kind of drug for treating fibroid is provided, certain mistakes of body can be corrected It adjusts, removes the Recurrence of myomata, reduce the chance of transfer, change myomata constitution, Clinical Practice, therapeutic effect is good, nontoxic Side effect.

The present invention is for the technical solution adopted for solving the technical problem：

A kind of drug for treating fibroid, the bulk pharmaceutical chemicals by its active ingredient as unit of parts by weight, is made are：Saltcake 15 ~25 parts, 10~20 parts of cassia twig, 20~30 parts of seaweed, 15~35 parts of Radix Salviae Miltiorrhizae, 10~20 parts of Snakegourd Fruit,Tangerine seed20~30 parts,Hawthorn 20~30 parts,The root of bidentate achyranthes15~35 parts, 20~30 parts of dragon's blood, 20~30 parts of fritillaria, 15~35 parts of semen brassicae, 10~20 parts of trigone, 20~30 parts of coix seed, 15~25 parts of Prunella vulgaris, 20~30 parts of peach kernel, 20~30 parts of Southern Star, 15~35 parts of radix paeoniae rubra, Radix Glycyrrhizae 20~ 40 parts,Pollen Typhae10~30 parts, 15~35 parts of excrementum pteropi, 20~30 parts of frankincense, 20~30 parts of myrrh, 15~25 parts of glutinous rehmannia, bavin 15~25 parts recklessly.

The drug of the treatment fibroid is formed, saltcake by the following raw materials medicine as unit of parts by weight is refined 20 parts, 15 parts of cassia twig, 25 parts of seaweed, 25 parts of Radix Salviae Miltiorrhizae, 15 parts of Snakegourd Fruit,Tangerine seed25 parts,Hawthorn25 parts,The root of bidentate achyranthes25 parts, dragon's blood 25 Part, 25 parts of fritillaria, 25 parts of semen brassicae, 15 parts of trigone, 25 parts of coix seed, 20 parts of Prunella vulgaris, 25 parts of peach kernel, 25 parts of Southern Star, radix paeoniae rubra 25 parts, 30 parts of Radix Glycyrrhizae,Pollen Typhae20 parts, 25 parts of excrementum pteropi, 25 parts of frankincense, 25 parts of myrrh, 20 parts of glutinous rehmannia, 20 parts of radix bupleuri.

The dosage form of the drug for the treatment of fibroid recited above is pill.

The drug and preparation method thereof of the treatment fibroid, specific procedure of processing are as follows：

A, weigh the parts by weight a raw material crush respectively after, cross 110 mesh sieve to obtain fine powder, proportionally be uniformly mixed it is mixed Close traditional Chinese medicine powder A；

B, water and honey is added to stir to obtain ointment shape into mixing traditional Chinese medicine powder A；

C, wet ball in pellet processing machine is made in ointment shape, carries out round as a ball, polishing.

D, the wet ball that step C is obtained is dried, is screened, quality inspection, packaging.

The positive beneficial effect of the present invention is as follows：

1, the drug of present invention treatment fibroid, be based on motherland's traditional Chinese medicine and pharmacy theory, in conjunction with clinical practice for many years, It is formulated exquisite, is filtered out from motherland's medicine treasure-house with relieving inflammation or internal heat detumescence, the promoting flow of qi and blood circulation, broken silt disappears tumor, eliminating stasis to resolve swelling, eliminating the phlegm It is wet, the drug of softening and resolving hard mass and other effects, in the drug component：Saltcake：Taste is salty, bitter, cold in nature, returns stomach, large intestine channel, relieving constipation by purgation, Moistening for dryness and softening hard mass, relieve inflammation or internal heat 20 parts of the effect of subsiding a swelling, cassia twig：Acrid, sweet, warm enter lung, the heart, bladder warp, have sweating expelling pathogenic factors from muscles and skin, warm promoting menstruation The effect of arteries and veins, helps yang transforming qi；Seaweed：Bitter, salty, cold in nature, nontoxic, return lung, spleen, kidney, liver stomach have softening hard masses, dissolving phlegm, profit The effect of water, detumescence；Radix Salviae Miltiorrhizae：Bitter is slightly cold, converge to heart and liver channels, has promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood disappears The effect of carbuncle；Snakegourd Fruit：Cold in nature, sweet in flavor, slight bitter has the effect of clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, ease constipation；Tangerine seed：Bitter, property It is flat, return liver and kidney channel, there is the effect of qi-regulating, dissipating bind, analgesic；Hawthorn：Sour sweet, tepor, returns spleen, stomach, Liver Channel are strong with helping digestion The effect of stomach, scattered stasis；The root of bidentate achyranthes：Bitter, it is mild-natured, return liver and kidney channel, there is dispelling stasis of blood and stimulating the menstrual flow, filling liver kidney, strengthening the bones and muscles, diuresis is logical Leaching, the effect of ensurining proper downward flow of the blood；Dragon's blood：Sweet in flavor, salty, mild-natured, converge to heart and liver channels have promoting blood circulation analgesic therapy, removing blood stasis and hemostasis, expelling pus and promoting granulation The effect of；Fritillaria：Bitter, sweet, cold nature, return lung, the heart channel of Hang-Shaoyin have the effect of moistening lung, are used for cough with lung heat, and dry cough lacks phlegm, cloudy Consumptive disease is coughed, and sputum streaked with blood is coughed up；Semen brassicae：Acrid flavour, it is warm-natured, it attaches to the lung and stomach meridians 2, there is warm lung slit phlegm profit gas, mammary gland dissipating bind to remove obstruction in channels to relieve pain The effect of；Trigone：It is pungent, bitter, it puts down, Return liver, the spleen channel, there is the effect of blood-breaking, Xiao Ji Zhi Tong；Coix seed：It is sweet in flavor, light, property Cool, returns spleen, stomach, lung channel have water penetration wet, the effect of invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, detoxicating and resolving a mass；Prunella vulgaris：It is pungent, bitter, Cold, Return liver, gallbladder channel have the effect of clearing heat-fire, improving eyesight, mass dissipating and swelling eliminating；Peach kernel：Bitter, sweet, flat, the thoughts of returning home, liver, large intestine channel, tool Have promoting blood circulation, relax bowel, it is relieving cough and asthma the effect of；Southern Star：It is cool in nature, bitter, micro-pungent;Return lung, liver, the spleen channel;, have Relieve heat, eliminating the phlegm, it is relieving convulsion, analgesic the effect of；Radix paeoniae rubra：Bitter, cold nature return return liver warp, have clearing heat and cooling blood, the work(of removing blood stasis and analgesics Effect；Radix Glycyrrhizae：Sweet in flavor, mild-natured, the thoughts of returning home, spleen, lung, stomach have clearing heat and detoxicating, invigorate the spleen and benefit qi, moisten the lung and relieve the cough, alleviating analgesic work( Effect；Pollen Typhae：It is mild-natured.It is sweet in flavor, Return liver, pericardium channel.The effect of with promoting circulation of blood stagnation resolvation, inducing diuresis for treating strangurtia；Excrementum pteropi：Bitter but sweet flavor, property Temperature, Return liver, the spleen channel have the effect of promoting circulation of blood analgesic；Frankincense：Acrid flavour, hardship, warm-natured, the thoughts of returning home, liver, the spleen channel are stopped with blood-activating and qi-promoting Bitterly, the effect of detumescence and promoting granulation；Myrrh：Acrid flavour, hardship, mild-natured, the thoughts of returning home, liver, the spleen channel have the effect of scattered stasis pain, detumescence and promoting granulation； Glutinous rehmannia：Sweet in flavor, bitter, cold in nature, the thoughts of returning home, liver and kidney channel have effects that enrich blood with enriching yin and nourishing kidney, blood-nourishing, cool blood；Radix bupleuri：Taste It is pungent, bitter, cold nature, Return liver, courage, lung channel, have and inducing diaphoresis in, soothing liver-qi stagnation, yang invigorating, bring down a fever preventing malaria the effect of.

2, the present invention provides a kind of drug for treating fibroid, therapeutic effect is good, has no toxic side effect, can be from basic The symptoms such as upper treatment qi depression to blood stasis, phlegm wet stasis, dampness and heat stasis, kidney deficiency blood stasis, can improve the organism endocrine of patient, enhancing The constitution of patients with uterine myoma is very big to the recurrence and transfer benefit that prevent fibroid.

3, pharmaceutical preparation of the present invention is pill, it according to based on theory of traditional Chinese medical science, diagnosis and treatment based on an overall analysis of the illness and the patient's condition be principle, formula is reasonable, clothes It is easy to carry with convenient, after medication can dispersing stagnated hepatoqi, it is promoting blood circulation and removing blood stasis, be inherently eliminated factor existing for myomata, improve body It is internal unbalance, the probability of myomata transfer and recurrence is reduced, to change myomata constitution.

Clinical typical case：

Case 1, Lin, 28 years old, 10-15 days menstruation time, and blood volume is excessive, the period is short, and patient takes this pill, stops after a week Blood restores normal, later eumenorrhea, no recurrence after normal after one month.

Case 2, Lee, 38 years old, often there is the sense of abdomen falling inflation, aching pain in waist and back in company's white collar, is after diagnosing fibroid, It takes this drug after two weeks to restore normally, has consolidated one week again later, so far disease-free hair.

Case 3, Zhang, 43 years old, leukorrhea was excessively increased, and uterine cavity increases on inspection, and endometrial gland increases, in addition basin Chamber is congested, leukorrhea can be made to increase, fully recovered after taking this drug 3 weeks, no recurrence.

Case 4, the Qin, 35 years old, intermenstrual period dysmenorrhoea abdominal pain can extend to waist, thigh, weakness of limbs, hair It is cold, it can also vomit sometimes.Dysmenorrhoea is endometriosis symptom after diagnosing, takes this drug one month, and physical recovery is normal.

Four, specific implementation mode：

The present invention is made further explanation and description with reference to specific embodiment：

Embodiment 1, a kind of drug for treating fibroid are formed, awns by the following raw materials medicine as unit of parts by weight is refined 20 parts of nitre, 15 parts of cassia twig, 25 parts of seaweed, 25 parts of Radix Salviae Miltiorrhizae, 15 parts of Snakegourd Fruit,Tangerine seed25 parts,Hawthorn25 parts,The root of bidentate achyranthes25 parts, dragon's blood 25 Part, 25 parts of fritillaria, 25 parts of semen brassicae, 15 parts of trigone, 25 parts of coix seed, 20 parts of Prunella vulgaris, 25 parts of peach kernel, 25 parts of Southern Star, radix paeoniae rubra 25 parts, 30 parts of Radix Glycyrrhizae,Pollen Typhae20 parts, 25 parts of excrementum pteropi, 25 parts of frankincense, 25 parts of myrrh, 20 parts of glutinous rehmannia, 20 parts of radix bupleuri.

The dosage form of the drug of above-mentioned treatment fibroid is pill.

The drug and preparation method thereof of the treatment fibroid, specific procedure of processing are as follows：

A, weigh the parts by weight a raw material crush respectively after, cross 110 mesh sieve to obtain fine powder, proportionally be uniformly mixed it is mixed Close traditional Chinese medicine powder A；

B, water and honey is added to stir to obtain ointment shape into mixing traditional Chinese medicine powder A；

C, wet ball in pellet processing machine is made in ointment shape, carries out round as a ball, polishing.

D, the wet ball that step C is obtained is dried, is screened, quality inspection, packaging.

Embodiment 2, a kind of drug for treating fibroid, by the raw material that its active ingredient as unit of parts by weight, is made Medicine is：15 parts of saltcake, 10 parts of cassia twig, 20 parts of seaweed, 15 parts of Radix Salviae Miltiorrhizae, 10 parts of Snakegourd Fruit,Tangerine seed20 parts,Hawthorn20 parts,The root of bidentate achyranthes15 Part, 20 parts of dragon's blood, 20 parts of fritillaria, 15 parts of semen brassicae, 10 parts of trigone, 20 parts of coix seed, 15 parts of Prunella vulgaris, 20 parts of peach kernel, Southern Star 20 parts, 15 parts of radix paeoniae rubra, 20 parts of Radix Glycyrrhizae,Pollen Typhae10 parts, 15 parts of excrementum pteropi, 20 parts of frankincense, 20 parts of myrrh, 15 parts of glutinous rehmannia, radix bupleuri 15 parts.

Embodiment 3, a kind of drug for treating fibroid, by the raw material that its active ingredient as unit of parts by weight, is made Medicine is：25 parts of saltcake, 20 parts of cassia twig, 30 parts of seaweed, 35 parts of Radix Salviae Miltiorrhizae, 20 parts of Snakegourd Fruit,Tangerine seed30 parts,Hawthorn30 parts,The root of bidentate achyranthes35 Part, 30 parts of dragon's blood, 30 parts of fritillaria, 35 parts of semen brassicae, 20 parts of trigone, 30 parts of coix seed, 25 parts of Prunella vulgaris, 30 parts of peach kernel, Southern Star 30 parts, 35 parts of radix paeoniae rubra, 40 parts of Radix Glycyrrhizae,Pollen Typhae30 parts, 35 parts of excrementum pteropi, 30 parts of frankincense, 30 parts of myrrh, 25 parts of glutinous rehmannia, radix bupleuri 25 parts.

Embodiment 4, a kind of drug for treating fibroid, by the raw material that its active ingredient as unit of parts by weight, is made Medicine is：18 parts of saltcake, 13 parts of cassia twig, 23 parts of seaweed, 22 parts of Radix Salviae Miltiorrhizae, 13 parts of Snakegourd Fruit,Tangerine seed23 parts,Hawthorn23 parts,The root of bidentate achyranthes22 Part, 23 parts of dragon's blood, 23 parts of fritillaria, 22 parts of semen brassicae, 13 parts of trigone, 23 parts of coix seed, 28 parts of Prunella vulgaris, 23 parts of peach kernel, Southern Star 23 parts, 22 parts of radix paeoniae rubra, 27 parts of Radix Glycyrrhizae,Pollen Typhae17 parts, 22 parts of excrementum pteropi, 23 parts of frankincense, 23 parts of myrrh, 18 parts of glutinous rehmannia, radix bupleuri 18 parts.

Embodiment 5, a kind of drug for treating fibroid, by the raw material that its active ingredient as unit of parts by weight, is made Medicine is：22 parts of saltcake, 17 parts of cassia twig, 27 parts of seaweed, 29 parts of Radix Salviae Miltiorrhizae, 27 parts of Snakegourd Fruit,Tangerine seed27 parts,Hawthorn37 parts,The root of bidentate achyranthes29 Part, 27 parts of dragon's blood, 27 parts of fritillaria, 29 parts of semen brassicae, 17 parts of trigone, 27 parts of coix seed, 22 parts of Prunella vulgaris, 27 parts of peach kernel, Southern Star 27 parts, 29 parts of radix paeoniae rubra, 34 parts of Radix Glycyrrhizae,Pollen Typhae24 parts, 29 parts of excrementum pteropi, 27 parts of frankincense, 27 parts of myrrh, 22 parts of glutinous rehmannia, radix bupleuri 22 parts.

Claims (4)

1. a kind of drug for treating fibroid, it is characterised in that：By the raw material that its active ingredient as unit of parts by weight, is made Medicine is：15~25 parts of saltcake, 10~20 parts of cassia twig, 20~30 parts of seaweed, 15~35 parts of Radix Salviae Miltiorrhizae, 10~20 parts of Snakegourd Fruit,Tangerine seed20 ~30 parts,Hawthorn20~30 parts,The root of bidentate achyranthes15~35 parts, 20~30 parts of dragon's blood, 20~30 parts of fritillaria, 15~35 parts of semen brassicae, three 10~20 parts of rib, 20~30 parts of coix seed, 15~25 parts of Prunella vulgaris, 20~30 parts of peach kernel, 20~30 parts of Southern Star, radix paeoniae rubra 15~35 Part, 20~40 parts of Radix Glycyrrhizae,Pollen Typhae10~30 parts, 15~35 parts of excrementum pteropi, 20~30 parts of frankincense, 20~30 parts of myrrh, glutinous rehmannia 15~25 parts, 15~25 parts of radix bupleuri.

2. the drug for the treatment of fibroid according to claim 1, it is characterised in that：By following as unit of parts by weight Each bulk pharmaceutical chemicals are refined to be formed, 20 parts of saltcake, 15 parts of cassia twig, 25 parts of seaweed, 25 parts of Radix Salviae Miltiorrhizae, 15 parts of Snakegourd Fruit,Tangerine seed25 parts,Hawthorn 25 parts,The root of bidentate achyranthes25 parts, 25 parts of dragon's blood, 25 parts of fritillaria, 25 parts of semen brassicae, 15 parts of trigone, 25 parts of coix seed, 20 parts of Prunella vulgaris, peach 25 parts of benevolence, 25 parts of Southern Star, 25 parts of radix paeoniae rubra, 30 parts of Radix Glycyrrhizae,Pollen Typhae20 parts, 25 parts of excrementum pteropi, 25 parts of frankincense, 25 parts of myrrh, ground It is 20 parts yellow, 20 parts of radix bupleuri.

3. the drug for the treatment of fibroid according to claim 1 or 2, it is characterised in that：The treatment fibroid The dosage form of drug is pill.

4. the drug and preparation method thereof of the treatment fibroid described in claim 3, specific procedure of processing are as follows：

A, weigh the parts by weight a raw material crush respectively after, cross 110 mesh sieve to obtain fine powder, proportionally be uniformly mixed it is mixed Close traditional Chinese medicine powder A；

B, water and honey is added to stir to obtain ointment shape into mixing traditional Chinese medicine powder A；

C, wet ball in pellet processing machine is made in ointment shape, carries out round as a ball, polishing;

D, the wet ball that step C is obtained is dried, is screened, quality inspection, packaging.