CN1085785A - Ginseng deer YIYUAN GAO and preparation method thereof - Google Patents
Ginseng deer YIYUAN GAO and preparation method thereof Download PDFInfo
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- CN1085785A CN1085785A CN 93105616 CN93105616A CN1085785A CN 1085785 A CN1085785 A CN 1085785A CN 93105616 CN93105616 CN 93105616 CN 93105616 A CN93105616 A CN 93105616A CN 1085785 A CN1085785 A CN 1085785A
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Abstract
The present invention relates to a kind of oral soft extract and preparation method that is used for the treatment of diseases such as human body sexual impotence, premature ejaculation, soreness of the waist and knees, cardiopalmus, insomnia, dreaminess giddy, inappetence, fatigue and weak, pernicious anemia, hypotension, chronic renal illness.It is characterized in that:, use the polish of modern high technology biological engineering and form by 40 kinds of rare Chinese medicine prescriptions such as Radix Ginseng, the Radix Astragali, Testis Et penis Bovis seu Bubali, Colla cornus cervi, Hippocampus.Advantage is that its prescription not only paid attention to YANG invigorating, but also taken yin nourishing into account, forms the yang blood and qi giving young employees remedial-courses in general knowledge and vocational skills, two-ways regulation Human Physiology mechanism.The present invention is through 300 routine clinical observation on the therapeutic effect, and total effective rate reaches 93.8%, is that human body is prevented and cured diseases, the senior YIN nourishing and YANG strengthening medicine of yin nourishing tonifying YANG, yin yang complementarity, two-ways regulation.
Description
The present invention relates to a kind of oral Chinese medicine soft extract that is used for the human body YIN nourishing and YANG strengthening, ginseng deer YIYUAN GAO.Form by 40 kinds of rare Chinese medicine polish such as Radix Ginseng, Colla cornus cervi, Hippocampus, the Radix Astragali, cattle whips.
China's Chinese medicine thinks that kidney has main bone, gives birth to functions such as marrow, store essential substances, is referred to as the congenital foundation, " root of life ", is " the " center " that each organ of the vital organs of the human body is regulated.The process of old friend's bulk-growth, growth, aging also is the performance of kidney qi prosperity and decline process.In the prior art, with the medicine of diseases such as Chinese patent medicine soft extract treatment sexual impotence, premature ejaculation, cardiopalmus, insomnia, soreness of the waist and knees, inappetence, fatigue and weak, septicemia, pernicious anemia, hypotension, dreaminess dizziness, chronic renal illness, myocarditis, rheumatic heart disease, the existing sale on market.With No. 91300517.7 patented products of having authorized is example, and its Chinese medicinal ingredients is 17 herbal medicines such as Penis et testis cervi, Testis Et penis Bovis seu Bubali, Radix Ginseng Rubra, Arillus Longan, and it mainly is means with the Yang invigorating medicine, reaches strong human kidney, regulates equilibrium between yin and yang, diseases prevention, the purpose of curing the disease.But from Chinese medicine dialectical execute control, the viewpoint of medication, above-mentioned Chinese patent medicine patented product only makes up a prescription from one-side Yang nourishing-strengthening and has in mind, exists with regard to the moon and the deficiency and the defective of YANG invigorating tonifying YANG.Be the basic low of human body the moon, the basis after the tonifying YANG balance is also low.Though, cure the disease so can improve the regulatory mechanism of Human Physiology, diseases prevention, can not fundamentally strong physique, optimize the human body regulatory mechanism.
The objective of the invention is to overcome above-mentioned the deficiencies in the prior art part and senior YIN nourishing and YANG strengthening medicine ginseng deer YIYUAN GAO of a kind of yin yang complementarity, two-ways regulation and preparation method thereof is provided.
Goal of the invention of the present invention can be achieved by following technology: promptly adopt 40 flavor Chinese crude drug compositing formulas, the dosage of its prescription medicine of respectively distinguishing the flavor of is:
Radix Ginseng 60g Radix Astragali 50g Colla cornus cervi 15g Placenta Hominis 15g
Hippocampus 9g Colla Plastri Testudinis 15g Arillus Longan 20g Rhizoma Dioscoreae 20g
Radix Polygoni Multiflori Preparata 30g Semen Astragali Complanati 40g Fructus Lycii 30g Melanteritum 30g
Radix Rehmanniae 30g Radix Rehmanniae Preparata 30g Testis Et penis Bovis seu Bubali 90g Semen Cuscutae 40g
Herba Epimedii 30g Semen Allii Tuberosi 30g Herba Cistanches 15g Semen Juglandis 45g
Fructus Rubi 30g Fructus Rosae Laevigatae 30g Ootheca Mantidis 20g Fructus Corni 20g
Fructus Amomi 10g Fructus Crataegi 40g Fructus Jujubae 150g Fructus Psoraleae 40g
Semen Trigonellae 20g Os Draconis (forging) 20g Radix Cyathulae 30g Radix Morindae Officinalis 30g
Cortex Cinnamomi 20g Herba Cynomorii 30g Actinolitum 20g Herba Dendrobii 20g
Semen Nelumbinis (removing the heart) 20g Fructus Ligustri Lucidi 30g Lignum Aquilariae Resinatum 5g Rhizoma Homalomenae 20g
The preparation method of ginseng deer YIYUAN GAO is: the first,, respectively it is ground into fine powder with the Radix Ginseng 60g in the above-mentioned prescription, Hippocampus 9g, Melanteritum 30g, and standby; The second, again with the Colla cornus cervi 15g in the prescription, Colla Plastri Testudinis 15g respectively molten, place standby; Three, all the other 35 herbal medicines in the prescription are mixed, decoct with water three times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, again three decocting liquids are merged, be condensed into clear paste, relative density 1.21～1.25 when 60 ℃ of heat are surveyed; Four, refined honey, Colla cornus cervi (melting), Colla Plastri Testudinis are added respectively in the concentrated clear paste, and add an amount of crystal sugar, Saccharum Sinensis Roxb., be stirred well to evenly, add Radix Ginseng, Hippocampus, Melanteritum fine drug powder after the cooling more respectively, packing stirs, high temperature sterilize promptly gets the finished product ginseng deer YIYUAN GAO soft extract of brown or sepia semifluid paste, feeble QI, the sweet little bitterness of flavor.
Embodiment: description the 5th part of the present invention has been described clear, a complete most preferred embodiment, no longer repeats here.After this product made, its discriminating was undertaken by following method:
(1) gets this product and put the microscopically observation: calcium oxalate cluster crystal diameter 20～68 μ m, the sharp point of corner angle.Rhabdium is colourless, and is faint yellow or brown, cataclasm, and fine and closely woven band is arranged, light and dark, and band is straight or wavy.
(2) get this product 10g, add water 40ml, heated and boiled number minute filters and gets filtrate, puts on filter paper, dries, and drips ninhydrin solution on speckle, about 2～5 minutes of 100 ℃ of bakings, speckle is blue purple.
(3) get this product 10g, add water 40ml, stir the back and filter, get filtrate 10ml and put in the tool plug test tube, firmly jolting has the persistency foam to produce.
(4) get this product 40g, add water 100ml, fully stir the back placement and spend the night, add ammonia solution 2ml, jolting adds ethyl acetate 100ml again, divides and gets ethyl acetate liquid, and evaporate to dryness in the water-bath, residue add dehydrated alcohol 1ml makes dissolving, as need testing solution.Other gets the icariine reference substance, adds methanol and makes the solution that every 1ml contains 1mg, in contrast product solution.Test according to thin layer chromatography, draw need testing solution and each 5ml of reference substance solution, put respectively in same and contain on the silica gel H thin plate that sodium carboxymethyl cellulose is a binding agent, (10: 1: 1: be that developing solvent launches 1), taking-up was dried, and spray is with 105 ℃ of aluminum chloride test solutions with ethyl acetate-butanone-formic acid-water, baking approximate number minute, put under the ultra-violet lamp (365nm) and inspect, the test sample chromatograph with the corresponding position of reference substance chromatograph on, show the fluorescence speckle of same color.
(5) get this product 30g, add water to 100ml, after fully stirring, placement is spent the night.Its filtrate is got in filtration, puts to add ethyl acetate 100ml in the separatory funnel, and jolting is placed and made layering, divides and gets the Methane Carboxylic Acid layer, and water bath method, residue add ethyl acetate 1ml makes dissolving, as need testing solution.Other gets psoralen, the isopsoralen reference substance, add ethyl acetate and make the mixed solution that every 1ml contains 2mg, need testing solution and each 5ml of reference substance solution are drawn in product solution photograph thin layer chromatography test in contrast, put respectively on same-silica gel g thin-layer plate, with hexane-ethyl acetate (8: 2) is that developing solvent launches, taking-up is dried, and spray is put under the ultra-violet lamp (365nm) and inspected with 10% potassium hydroxide methanol solution.In the test sample chromatograph, with the corresponding position of reference substance chromatograph on, show the fluorescence speckle of same color.
Pharmacological evaluation conclusion of the present invention: acute toxicity testing is the result show, LD50 is for being equivalent to crude drug in whole 244.86 ± 0.02393g/kg, and long term toxicity test is the result show, do not find that obvious drug accumulation toxic reaction takes place.The main pharmacodynamics experiment shows, ginseng deer YIYUAN GAO seemingly has facilitation to female and male juvenile mouse sexual organ's growth, have and improve the effect of female mice body inner estrogen and follicule-stimulating hormone (FSH) level of growing up, and have the effect that improves androgen level in the bull mice body.Activity to the central nervous system of mice drug influence has dual regulation, and effective dysmnesia of improving the drug-induced aged mouse, can significantly improve the aged mouse ability of learning and memory.Can significant prolongation to mice heavy burden work done endurance, have certain antifatigue effect.And have and strengthen the effect of mice body non-specific immunity.
Clinical research conclusion of the present invention: through the 300 routine clinical observations of three families of Affiliated Hospital of Shaanxi College of Traditional Chinese Medicine, Traditional Chinese Medicine Research Institute, Shanxi Province Affiliated Hospital, No.1 Clinical College, Xi'an Medical Univ: to sexual impotence 88 examples, effective percentage is 93%, anemia 52 examples, effective percentage is 96%, hypotension 47 examples, and effective percentage is 96%, neurasthenia's 54 examples, effective percentage is 94%, slow kidney illness 59 examples, and effective percentage is 90%.Three tame provincial hospital observed results show that ginseng deer YIYUAN GAO has better therapeutic effect, total effective rate to reach 93.8% to sexual impotence, anemia, hypotension, neurasthenia, slow kidney illness etc., and without any side effects.The act case is as follows:
Example one: Fan * *, man, 58 years old, the accountant of bookstore.Symptom: because of being engaged in mental work for a long time, overwork, cause serious sexual impotence and insomnia, reach 9 years, health is weak, through failing to respond to any medical treatment in many ways, through one bottle of clothes " ginseng deer YIYUAN GAO ", makes great progress suddenly.Full recovery sleepiness every night, no dream, next day is energetic, serve on one bottle again, and sexual function is normal, has satisfactorily spent the sexual life first time after 9 years.
Example two: blue * *, woman, 26 years old, railway worker.Symptom: pernicious anemia, septicemia 3 years,, take " ginseng deer YIYUAN GAO " two bottles through failing to respond to any medical treatment in many ways after, the examination in hospital leukocyte obviously increases, body constitution is obviously recovered.
Example three: bent * *, the woman, 34 years old, certain cadre of motor corporation, dizzy weak 4 years of patient meets increase the weight of summer, is difficult to adhere to work sometimes, and blood pressure fluctuates between 11-12/7-10Kpa always, and when sx, the quiet glucose that pushes away can be alleviated slightly.Clothes ginseng deer YIYUAN GAO transference cure after one course of treatment, the check blood pressure is 15/11Kpa, not recurrence again of the state of an illness so far.
Example four: Miao * *, the woman, 32 years old, the worker of Xi'an post and telecommunications office, insomnia and dreamful sleep 8 years is surplus, poor appetite usually, spirit is also poor, takes GUIPI WAN, Chinese and Western drug effect such as stable is not remarkable, takes two bottles of ginseng deer YIYUAN GAO, sleep is normal, and dreaminess also removes, and the enhancing of sense spirit, and it is energetic to work.
Example five: the Meng * *, man, 17 years old, power plant, Weihe River job-waiting youth.Suffered from chronic glomerulonephritis 7 years, urine routine test, albumen be in (+-++), and erythrocyte is between (++-+++), once invalid always with the treatment of medicines such as hormone, introduce my institute through the acquaintance, clothes ginseng deer YIYUAN GAO first quarter moon urine protein is turned out cloudy, erythrocyte a little, recovery from illness is left hospital, and continues medication and consolidates.
The present invention's advantage compared to existing technology is: both establishing-Yangs, and again enriching yin makes human body reach yin yang complementarity, and the strong physique of bidirectional modulation is cured the disease, the purpose of diseases prevention. The prescription characteristics that show ginseng deer plaster for replenishing vital essence are under the traditional Chinese medicine and pharmacy theoretical direction, according to the meaning of Yin grows while yang is generating, on the basis of paying attention to yang-tonifying, take again yin-nourishing into account, so the yang blood and qi giving young employees remedial-courses in general knowledge and vocational skills focuses on the tonifying Qi establishing-Yang. Positive so-called " qi and blood is all wanted, and elder generation is being enriched blood in tonifying Qi, and negative and positive also need, and establish the yang function on enriching yin ". Kidney tonifying is held concurrently with the reason spleen and is gone, and elder generation will lay equal stress in the another characteristics of prescription of the present invention the day after tomorrow. Studies have shown that the present invention contains the necessary polypeptide of human kidney, amino acid, VB、V
E、V
ADeng the special dietary composition, to multiple illness such as impotence, premature ejaculation, pernicious anaemia, low blood pressure, the treatment that recovers renal function, myocarditis, rheumatic heart disease all had significant curative effect.
Claims (2)
1, a kind of oral Chinese medicine soft extract that is used for the human body YIN nourishing and YANG strengthening--ginseng deer YIYUAN GAO, it is characterized in that: prescription is made up of 40 kinds of Chinese crude drugs, and the dosage of each herbal medicine prescription is:
Radix Ginseng 60g Radix Astragali 50g Colla cornus cervi 15g Placenta Hominis 15g
Hippocampus 9g Colla Plastri Testudinis 15g Arillus Longan 20g Rhizoma Dioscoreae 20g
Radix Polygoni Multiflori Preparata 30g Semen Astragali Complanati 40g Fructus Lycii 30g Melanteritum 30g
Radix Rehmanniae 30g Radix Rehmanniae Preparata 30g Testis Et penis Bovis seu Bubali 90g Semen Cuscutae 40g
Herba Epimedii 30g Semen Allii Tuberosi 30g Herba Cistanches 15g Semen Juglandis 45g
Fructus Rubi 30g Fructus Rosae Laevigatae 30g Ootheca Mantidis 20g Fructus Corni 20g
Fructus Amomi 10g Fructus Crataegi 40g Fructus Jujubae 150g Fructus Psoraleae 40g
Semen Trigonellae 20g Os Draconis (forging) 20g Radix Cyathulae 30g Radix Morindae Officinalis 30g
Cortex Cinnamomi 20g Herba Cynomorii 30g Actinolitum 20g Herba Dendrobii 20g
Semen Nelumbinis (removing the heart) 20g Fructus Ligustri Lucidi 30g Lignum Aquilariae Resinatum 5g Rhizoma Homalomenae 20g
2, a kind of preparation method that is used for the described ginseng of claim 1 deer YIYUAN GAO is characterized in that:
A, get Radix Ginseng 60g, Hippocampus 9g, Melanteritum 30g, respectively it is ground into fine powder;
B, get respectively molten of Colla cornus cervi 15g, Colla Plastri Testudinis 15g;
C, all the other 35 flavors are mixed, decoct with water three times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, again three decocting liquids are merged, be condensed into clear paste, relative density 1.21～1.25 when 60 ℃ of heat are surveyed;
D, refined honey and the described Colla cornus cervi (melting) of b, Colla Plastri Testudinis are added respectively in the concentrated clear paste of above-mentioned c, and add an amount of crystal sugar, Saccharum Sinensis Roxb., be stirred well to evenly;
E, treat to add the described Radix Ginseng of a, Hippocampus, Melanteritum fine drug powder more respectively after the d cooling, stir high temperature sterilize.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 93105616 CN1085785A (en) | 1993-05-04 | 1993-05-04 | Ginseng deer YIYUAN GAO and preparation method thereof |
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| CN 93105616 CN1085785A (en) | 1993-05-04 | 1993-05-04 | Ginseng deer YIYUAN GAO and preparation method thereof |
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| CN1085785A true CN1085785A (en) | 1994-04-27 |
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| CN 93105616 Pending CN1085785A (en) | 1993-05-04 | 1993-05-04 | Ginseng deer YIYUAN GAO and preparation method thereof |
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| CN1058181C (en) * | 1997-07-04 | 2000-11-08 | 内蒙古太仆寺旗草原酿酒有限责任公司 | Health-care wine |
| CN1059817C (en) * | 1997-10-16 | 2000-12-27 | 沈广兴 | Traditional Chinese medicine preparation for reinforcing the kidney and enhancing fitness of old age people |
| CN1070055C (en) * | 1994-08-08 | 2001-08-29 | 云南省思茅地区医药公司制药厂 | Deerhorn glue oral liquid |
| WO2003037246A2 (en) * | 2001-07-17 | 2003-05-08 | Integrated Chinese Medicine Holdings Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| CN1294949C (en) * | 2005-04-14 | 2007-01-17 | 杨艳贞 | Chinese medicinal preparation for treating sexual dysfunction, menoxenia, aciesis and developing immunity |
| CN100333755C (en) * | 2005-10-31 | 2007-08-29 | 李顺定 | Nephrosis treating Chinese medicine boneyed bolus and its prepn process |
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1993
- 1993-05-04 CN CN 93105616 patent/CN1085785A/en active Pending
Cited By (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1070055C (en) * | 1994-08-08 | 2001-08-29 | 云南省思茅地区医药公司制药厂 | Deerhorn glue oral liquid |
| CN1058181C (en) * | 1997-07-04 | 2000-11-08 | 内蒙古太仆寺旗草原酿酒有限责任公司 | Health-care wine |
| CN1059817C (en) * | 1997-10-16 | 2000-12-27 | 沈广兴 | Traditional Chinese medicine preparation for reinforcing the kidney and enhancing fitness of old age people |
| WO2003037246A2 (en) * | 2001-07-17 | 2003-05-08 | Integrated Chinese Medicine Holdings Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| WO2003037246A3 (en) * | 2001-07-17 | 2003-10-30 | Integrated Chinese Medicine Ho | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| US6855344B2 (en) | 2001-07-17 | 2005-02-15 | Integrated Chinese Medicine Holdings, Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| US7465466B2 (en) | 2001-07-17 | 2008-12-16 | Integrated Chinese Medicine Holdings, Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| US7223424B2 (en) | 2001-07-17 | 2007-05-29 | Integrated Chinese Medicine Holdings, Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| CN100335084C (en) * | 2003-04-01 | 2007-09-05 | 四川倍达尔新技术开发有限公司 | Compound Chinese medicine for treating leukoplakia vulvae and its preparation method |
| US7449202B1 (en) | 2003-07-10 | 2008-11-11 | Integrated Chinese Medicine Holdings, Ltd. | Compositions and methods for prostate and kidney health and disorders, an herbal preparation |
| CN1294949C (en) * | 2005-04-14 | 2007-01-17 | 杨艳贞 | Chinese medicinal preparation for treating sexual dysfunction, menoxenia, aciesis and developing immunity |
| CN100333755C (en) * | 2005-10-31 | 2007-08-29 | 李顺定 | Nephrosis treating Chinese medicine boneyed bolus and its prepn process |
| CN100441207C (en) * | 2006-03-23 | 2008-12-10 | 重庆科瑞南海制药有限责任公司 | Medicine for treating male's renal insufficiency and its preparing method |
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| CN102895356B (en) * | 2012-09-10 | 2013-08-07 | 顾康春 | Traditional Chinese medicine for treating anaemia |
| CN103768462A (en) * | 2012-10-22 | 2014-05-07 | 周美月 | Orthomolecular nutritious traditional Chinese medicine oral liquid for nourishing yin, tonifying yang, strengthening kidney and maintaining health |
| CN103340921A (en) * | 2013-07-12 | 2013-10-09 | 武汉市健恒药业有限公司 | Traditional Chinese medicine for treating insufficiency of both the spleen and the kidney and preparation method thereof |
| CN103340921B (en) * | 2013-07-12 | 2015-02-25 | 武汉市健恒药业有限公司 | Traditional Chinese medicine for treating insufficiency of both the spleen and the kidney and preparation method thereof |
| CN104432047A (en) * | 2014-12-10 | 2015-03-25 | 无锡瑞年实业有限公司 | Capsule for reinforcing immunity |
| CN104382038A (en) * | 2014-12-10 | 2015-03-04 | 无锡瑞年实业有限公司 | Soft capsule for improving immunity |
| CN104382038B (en) * | 2014-12-10 | 2016-02-03 | 无锡瑞年实业有限公司 | A kind of soft capsule for improving immunity |
| CN104432047B (en) * | 2014-12-10 | 2016-03-09 | 无锡瑞年实业有限公司 | A kind of capsule of develop immunitypty |
| WO2016141774A1 (en) * | 2015-03-11 | 2016-09-15 | 吉林肽谷生物工程有限责任公司 | Uses of jilin ginseng oligopeptide in preparing food product or healthcare food product for improving and enhancing sexual function |
| CN106213487A (en) * | 2016-07-19 | 2016-12-14 | 辽宁未来生物科技有限公司 | A kind of tonifying kidney and nourishing liver biological health preparation and production technology |
| CN107660703A (en) * | 2016-07-28 | 2018-02-06 | 赵素娟 | longan leek seed pig kidney and preparation method thereof |
| CN106266309A (en) * | 2016-09-09 | 2017-01-04 | 成都市飞龙水处理技术研究所 | A kind of can the Chinese medicine composition and preparation method thereof of effective resisting fatigue |
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