CN103006985A - Traditional Chinese medicine composition for curing insomnia - Google Patents

Abstract

The invention discloses a drug composition for curing insomnia, which is characterized by comprising the following traditional Chinese medicines in part by weight: 25 parts of mimosa pudica, 40-50 parts of elephantopus scaber, 40-50 parts of masson pine, 20-25 parts of acanthopanax, 20-25 parts of Yandang Marattioid ferns, 20-25 parts of creeping oxalis, 20-25 parts of jujube kernels, 20-25 parts of Chinese yams, 20-25 parts of angelica sinensis, 20-25 parts of concha ostreae, 15-20 parts of albizia flowers, 15-20 parts of schisandra chinensis, 15-20 parts of salvia miltiorrhiza, 15-20 parts of rhizoma corydalis, 15-20 parts of tuber fleeceflower stems, 15-20 parts of codonopsis pilosula, 15-20 parts of radix polygoni multiflori preparata, 15-20 parts of Herba Polygalae Japonicae, 15-20 parts of herba epimedii, 15-20 parts of rhizoma atractylodis macrocephalae, 15-20 parts of poria with hostwood, 15-20 parts of herba hyperici japonica, 10-12 parts of pinellia ternate, 10-12 parts of donkey-hide gelatin, 10-12 parts of semen boitae,10-12 parts of rhizoma nardostachyos and 90 parts of liquorice. The drug composition has a better therapeutical effect on insomnia.

Description

A kind of Chinese medicine proved recipe for the treatment of of insomnia patients

Technical field

The present invention relates to a kind of Chinese medicine proved recipe, this proved recipe has preferably therapeutical effect for the insomnia.

Background technology

Insomnia is one of common clinical disease, though do not belong to critical illness, hinders people orthobiosis, work, study and health, and can increase the weight of or bring out the diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy, brings long-term misery to patient.When preclinical therapy insomnia, multiplex stable class medicine is (such as nitrodiazepam, estazolam, ALprazolanic, stable, fludiazepam etc.Sleeping pill is in vivo mostly through liver, renal metabolism, long-term taking can increase the burden of Liver and kidney, have also can cause liver enlargement, hepatalgia, jaundice, edema, albuminuria, hematuria and feel sick, hepatic and renal function injure and the intestines and stomach reactions such as abdominal distention, inappetence, constipation.

Insomnia is called " unable to close the eyes ", " insomnia ", " must not crouch " in " interior warp ", and thinks that the insomnia reason mainly contains two kinds: the one, and the impact of other diseases such as cough, vomiting, abdominal distention etc., makes the people must not peacefully sleeping; The 2nd, negative and positive of qi and blood is become estranged, make the people not the able person sleep.

The traditional Chinese medical science is rather abundant about the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of insomnia, and many doctors seek the mechanism of its generation from clinical practice in recent years, have proposed a little new dialectical thinkings.

Technology contents

The purpose of this invention is to provide a kind of Chinese medicine proved recipe and using method thereof, this proved recipe has preferably therapeutical effect to the insomnia.

Chinese medicine proved recipe of the present invention is comprised of according to weight portion following Chinese medicine:

25 parts of Herba Mimosae Pudicaes, Herba Lespedezae Cuneatae, 40～50 parts of Pinus massoniana Lamb, Radix Et Caulis Acanthopanacis Senticosi, wild goose swing lotus throne Herba pteridii latiusculi, Herba Oxalidis Corniculatae, Semen Ziziphi Spinosae, Rhizoma Dioscoreae, Radix Angelicae Sinensis, 20～25 parts of Concha Ostreaes, Flos Albiziae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Caulis Polygoni Multiflori, Radix Codonopsis, Radix Polygoni Multiflori Preparata, Herba Polygalae Japonicae, Herba Epimedii, the Rhizoma Atractylodis Macrocephalae, Poria cum Radix Pini, 15～20 parts of Herba Hyperici Japonici, Rhizoma Pinelliae Preparata, Colla Corii Asini bead, Semen Platycladi, 10～12 parts of Radix Et Rhizoma Nardostachyos, 90 parts in Radix Glycyrrhizae.

Chinese medicine proved recipe of the present invention weight portion proportioning commonly used consists of:

25 parts of Herba Mimosae Pudicaes, 40 parts of Herba Lespedezae Cuneatae, 50 parts of Pinus massoniana Lamb, 20 parts of Radix Et Caulis Acanthopanacis Senticosis, wild goose swings 20 parts of lotus throne Herba pteridii latiusculis, 20 parts of Herba Oxalidis Corniculataes, 20 parts of Semen Ziziphi Spinosaes, 20 parts of Rhizoma Dioscoreaes, 20 parts of Radix Angelicae Sinensis, 20 parts of Concha Ostreaes, 15 parts of Flos Albiziaes, 15 parts of Fructus Schisandrae Chinensis, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Corydalis, 15 parts of Caulis Polygoni Multiflori, 15 parts of Radix Codonopsis, 15 parts of Radix Polygoni Multiflori Preparata, 15 parts of Herba Polygalae Japonicae, 15 parts of Herba Epimedii, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Poria cum Radix Pinis, 15 parts of Herba Hyperici Japonici, 10 parts of Rhizoma Pinelliae Preparata, 12 parts of Colla Corii Asini beads, 12 parts of Semen Platycladi, 12 parts of Radix Et Rhizoma Nardostachyos, 90 parts in Radix Glycyrrhizae.

The using method of Chinese prescription of the present invention is, require to select medical material to place marmite according to part by weight, adding for the first time approximately, the treble water gaging decocts once, leach medicinal residues, for the second time add approximately that two times of weight decoctings boil once, decocted 25～30 minutes at every turn, the elimination medicinal residues, merge medicine juice, taken three times a day, each 250ml.

This medicine proved recipe is after Chinese medical discrimination analysis insomnia's the reason of having concentrated on studies, according to the accumulation that motherland's medical use pharmacology is touched upon and put into practice, the new medicinal proved recipe of proposition.

From traditional Chinese medical science angle, the sick position of insomnia is mainly at heart, and it is dirty to relate to liver, spleen (stomach), kidney three.The normal operation of all functions of body and coordination, the operation of the gas of yin-Yang is also normal, and then people's sleep is normal, otherwise, insomnia will appear.Concrete manifestation is as follows: disturb (stomach), hyperactivity of fire caused by deficiency of YIN (kidney), deficiency of both the heart and spleen (heart spleen), the heart and gallbladder deficiency of vital energy (heart and gallbladder) in pathogenic fire derived from stagnation of liver-QI (liver), the expectorant heat.

Medicine proved recipe of the present invention, the side separates as follows:

Monarch drug: Herba Mimosae Pudicae, Herba Lespedezae Cuneatae, Pinus massoniana Lamb, Radix Et Caulis Acanthopanacis Senticosi, wild goose swing lotus throne Herba pteridii latiusculi, Herba Oxalidis Corniculatae, Flos Albiziae, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Caulis Polygoni Multiflori, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Colla Corii Asini bead, Radix Codonopsis, Radix Polygoni Multiflori Preparata, Semen Platycladi, Herba Polygalae Japonicae, Herba Epimedii, Rhizoma Pinelliae Preparata, Concha Ostreae, Radix Et Rhizoma Nardostachyos, Poria cum Radix Pini, the strong the five internal organs of reinforcing the heart, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, calming soporific.

Ministerial drug: the Rhizoma Atractylodis Macrocephalae, invigorating the spleen and replenishing QI, strengthening superficial resistance to stop perspiration.

Adjuvant drug: Herba Hyperici Japonici, heat-clearing and toxic substances removing, dampness removing jaundice eliminating, detumescence dissipating blood stasis.

Make medicine: Radix Glycyrrhizae, the hot cold expelling of dispelling, yin nourishing blood, tonifying the spleen and stomach, coordinating the actions of various ingredients in a prescription.

From the herbal pharmacology attribute, the property of medicine of the various Chinese crude drugs of selecting is as follows:

Herba Mimosae Pudicae has ataralgesia, detoxifcation dissipating blood stasis, hemostasis convergence, clearing away heat and promoting diuresis, the effects such as preventing phlegm from forming and stopping coughing.Guangzhou army " Chinese herbal medicine the handbook commonly used: " calmness of calming the nerves.”

Herba Lespedezae Cuneatae, clearing away heat-damp and promoting diuresis helps digestion except long-pending expelling phlegm for arresting cough, inducing diuresis for treating stranguria syndrome.According to " interior warp " analysis for insomnia, " cough ", " vomiting ", " abdominal distention " are the sources for insomnia, can cure with Herba Lespedezae Cuneatae.In Journal of Traditional Chinese Medicine " folks of china therapy " the 03rd phase in 2002, Hong Dingqiao uses Herba Lespedezae Cuneatae, and Cure for insomnia is obtained better effects.

Pinus massoniana Lamb has dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching, the effect of blood-promoting and mind-easing." China's book on Chinese herbal medicine " claims its volatile oil that central nervous system of mice is had sedation.Zhao Guizhi, the people such as Shou Dan have studied " the different extract sedative-hypnotic effects of Folium Pini reach the impact on brain neurotransmitter " experimental result and have confirmed that Pinus massoniana Lamb has certain curative effect for insomnia at " Chinese Chinese medicine magazine ".

Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Shennong's Herbal divides and classifies them as top grade, middle product.Numerous scientific publications about Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi have proved its antifatigue effect, strengthen endurance and ability, increase the effect of alert and resourceful and learning capacity.The clinical experiment confirmation, its extract has sedation to the central nervous system, can prolong the hexenoic aldehyde anesthesia duration, reduces the postanesthetic irritability of hexenoic aldehyde." Pharmacology and Clinics of Chinese Materia Medica " 06 phase in 2011, Hu Wenting, the people such as Li Tingli confirm that by " Radix Et Caulis Acanthopanacis Senticosi and Fructus Schisandrae Chinensis contract are to the research of Sedative And Hypnotic Effect " Radix Et Caulis Acanthopanacis Senticosi can effectively prolong the length of one's sleep, Fructus Schisandrae Chinensis then can shorten Sleep latency, Papillary has better effect for Cure for insomnia.

Wild goose swings the lotus throne Herba pteridii latiusculi, runs into local medicinal herb grower in the Wild Goose and Reed Marsh Mountains, and they can tell you proudly: " wild goose swings three treasured---Flos Lonicerae, bracketplant, centering grass "." centering grass " is wild goose and swings the lotus throne Herba pteridii latiusculi, and rhizome and petiole base contain flavonoid, phenols character, and the effect of tranquilizing and curing mania is arranged, and the locality is usually used in treating the insomnia that the neurasthenia causes.

Herba Oxalidis Corniculatae, all herbal medicine has heat-clearing and toxic substances removing, the effectiveness of Sweeling-eliminating medicine powder disease.Clinical practice: Cure for insomnia is got 10 jin of Oxalis corniculata Linn., 2 jin in Folium Pini, adds water 8000mL, fries in shallow oil filter and remove residue 1 hour; Other gets 1 jin in Fructus Jujubae and smashs to pieces, adds water 2000mL and fries in shallow oil filter and remove residue 1 hour.Two liquid are mixed, add proper amount of sugar and antiseptic is for subsequent use.Every 15～20mL that takes, every day 3 times.Certain calmness is arranged, the effect of sleeping peacefully.

Flos Albiziae, Flos Albiziae has calming effects, mainly is to control the effects such as pent-up is uncomfortable in chest, insomnia forgetfulness, nourishing YIN and invigorating YANG, ophthalmic, neurasthenia.The clinical disarmony between the heart and kidney of controlling is had a sleepless night: Flos Albiziae, Cortex Cinnamomi, Rhizoma Coptidis, Caulis Polygoni Multiflori.Decoction.

Semen Ziziphi Spinosae nourishes heart, and calms the nerves arresting sweating.Be used for neurasthenia, insomnia, dreaminess, night sweat." Prescriptions for Universal Relief " with the Semen Ziziphi Spinosae arresting sweating, the Radix Ginseng replenishing and restoring lung-QI, and Poria is calmed the nerves.Be used for the empty spontaneous perspiration of body, night sweat.Because the three again can tranquilizing by nourishing the heart, therefore also can be used for restlessness of asrhenia type and insomnia.Holy Benevolent Prescriptions is with the Semen Ziziphi Spinosae tranquilization and nourishing, and the Radix Rehmanniae yin nourishing clears away heart-fire.Be used for insufficiency of heart-YIN, vexed heating, palpitation and insomnia.

Radix Salviae Miltiorrhizae, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.

Rhizoma Corydalis, Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.Promoting blood circulation to remove blood stasis is arranged, the function of promoting the circulation of QI pain relieving.Caulis Polygoni Multiflori,

Rhizoma Dioscoreae, " Japan hanako materia medica " say that Rhizoma Dioscoreae helps the five internal organs, bone and muscle strengthening, and long will is calmed the nerves, and the main essence of letting out is forgetful." property of medicine book on Chinese herbal medicine " then thought, Rhizoma Dioscoreae can be mended five kinds of strain and seven kinds of impairment, goes cool breeze, and relieving palpitation is refreshing, the peace soul, and reinforcing the heart gas lacks, many accounts.

Colla Corii Asini bead, nourishing YIN and moistening the lung is used for the diseases such as vexed, insomnia, spasm of hyperactivity of fire caused by deficiency of YIN.

Radix Codonopsis, clinical Qi-tonifying drug commonly used, function invigorating the spleen to benefit the lung, effect person of modern times ginseng and for a little less than, be applicable to the various deficiency of vital energy deficiency persons, the compatibility application such as the normal and Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae; The disease of the deficiency of both QI and blood that causes such as blood deficiency and yellow complexion and chronic hemorrhage illness is joined hematonic such as Radix Rehmanniae Preparata, Radix Angelicae Sinensis etc.Disorder of QI and blood is one of root of insomnia, and the comprehensive benefiting action of Radix Codonopsis can effectively be treated disorder of QI and blood.Modern medicine study confirms that Radix Codonopsis itself just has calmness, hypnosis, anticonvulsant action.

Radix Polygoni Multiflori Preparata has the effect of nourishing kidney yin.To diseases such as the spiritlessness and weakness due to the blood failing to tonify the heart, shortness of breath and palpitation, insomnia forgetfulness, dreaminess seminal emissions, available Radix Polygoni Multiflori Preparata 15 grams, adapted Caulis Polygoni Multiflori, Radix Salviae Miltiorrhizae, each 15 gram of Radix Polygalae.Day potion, decocting twice, at twice decoction being taken warmly.With replenishing blood for nourishing heart, tranquilizing the mind.

Semen Platycladi, tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Be used for restlessness of asrhenia type and insomnia, severe palpitation, the diseases such as dryness of the intestine constipation.Lack of preservation of spirit, palpitation with fear is in a trance, and is nervous, insomnia, seminal emission, the night sweat person should eat.Compendium of Material Medica: " gas that nourishes heart, the profit kidney is dry, and the peace soul is decided soul, and Fructus Alpiniae Oxyphyllae is allayed excitement." just says in the Holy Benevolent Prescriptions: " control the hectic fever due to YIN-deficiency sleeplessness, vexed: with Semen Platycladi one or two, two in water grinds the strand extracting juice, and lower Semen oryzae sativae two closes, and cooks congee that it is ripe to wait, and lower Radix Rehmanniae juice one closes, and boils even the food again.”

Herba Polygalae Japonicae, " middle traditional Chinese medicines are planted illustrated handbook ": " root is calm, expectorant, the energy intelligence promoting and the mind tranquilizing, and loose strongly fragrant reducing phlegm disappears red swollen.Control bronchitis, pneumonia, cough ant phlegm, palpitation with fear, forgetful carbuncle skin ulcer is swollen, sore throat.”

Herba Epimedii can be expanded all blood vessels, improves microcirculation, increases blood flow, increases coronary flow; Antitussive arranged, eliminate the phlegm, anti-hypoxia, calmness, anticonvulsant action

Rhizoma Pinelliae Preparata, drying dampness to eliminate phlegm.Be used for the abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache.

Concha Ostreae has convergence, calmness, detoxifcation, analgesic effect.

Radix Et Rhizoma Nardostachyos, the Radix Et Rhizoma Nardostachyos merit contains the Multiple components such as Fructus Aristolochiae is rare, jatamansone in promoting the circulation of QI to relieve pain, reason spleen appetizing, has calm stable, arrhythmia and alleviates the effects such as lung and gastrointestinal smooth muscular spasm; Be equipped with the Cinnabaris Poria cum Radix Pini of the eliminating phlegm of having one's ideas straightened out, the Rhizoma Acori Graminei of regulating the flow of vital energy and mind tranquilizing and the heart calming with Radix Et Rhizoma Nardostachyos, three flavor medicines all have calm effect, brew together then and can strengthen synergism.

The Rhizoma Atractylodis Macrocephalae, invigorating the spleen and replenishing QI, strengthening superficial resistance to stop perspiration.

Herba Hyperici Japonici, heat-clearing and toxic substances removing, dampness removing jaundice eliminating, detumescence dissipating blood stasis.Be used for jaundice due to damp-heat, acute appendicitis, conjunctival congestion and swelling pain, hot carbuncle toxin; Closely be useful on acute, chronic hepatitis, early stage liver cirrhosis, hepatalgia, appendicitis, mastitis, pulmonary abscess.

Radix Glycyrrhizae, treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, detoxifcation, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Give birth to pathogenic fire purging heat, the ripe usefulness exterior cold of fall apart is gone pharyngalgia, except pathogenic heat, delays healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening.

Poria cum Radix Pini: fine person, square-cut thin slice, function mind tranquilizing and the heart calming are entertained in the Poria center.

Medicine proved recipe of the present invention, what adopt for the treatment of insomnia is the thinking of " regulating QI is nourished blood, tranquilizing by nourishing the heart ", stable neural along the reason motive by regulating interior internal organs, reaches the purpose of Cure for insomnia.

Technical scheme of the present invention, through clinical front zoopery, tentative confirmation has preferably pharmacological effect, specifically tests as follows:

1. materials and methods

1.1 laboratory animal

Cleaning level male SD rat (SPF grade) 20, body weight 180～200g.Laboratory animal adapted to first for 1 week before the experiment.Laboratory condition is 18～22 ℃ of room temperatures, and free diet provides sufficient drinking-water and standard Mus feedstuff, the control interfering noise, and day alternates with night for 12h/12h.

1.2 Experimental agents

Pentobarbital sodium is purchased to Pharmaceutical Group Solution on Chemical Reagents in Shanghai company, and diazepam is available from Medical University Of Anhui attached First Hospital pharmacy, and sodium carboxymethyl cellulose is purchased to Guangzhou pharmaceuticals chemical reagent glass apparatus wholesale department.0.5% carboxymethylcellulose sodium solution is dissolved in by the 0.5g sodium carboxymethyl cellulose joins in the 100mL distilled water; 0.1% pentobarbital sodium solution is dissolved in by the pentobarbital sodium powder joins in the distilled water.Chinese medicine need testing solution and diazepam solution are dissolved in by test sample, diazepam (stabilizing) joins in 0.5% the sodium carboxymethyl cellulose.

1.3 experiment grouping

20 SD rats are divided into Normal group, negative control group, diazepam group, Chinese medicine test sample group at random, 5 of every group of rats.Except Normal group does not award any processing, negative control group, diazepam group, test sample group gavage respectively 0.5% sodium carboxymethyl cellulose, diazepam solution (dosage according to the 0.002g/kg body weight gavages), need testing solution (dosage according to the 3g/kg body weight gavages), administering mode is gavage, and the dosage volume is 4mL.

1.4 the mensuration of Sleep latency and the length of one's sleep

Behind the perfusion 1h, each treated animal is according to the dosage lumbar injection 0.1% pentobarbital sodium solution of 55mg/kg, the time of recording every rats by intraperitoneal injection 0.1% pentobarbital sodium solution, the time that the time of righting reflex loss and righting reflex begin to occur.Time from the lumbar injection pentobarbital sodium to righting reflex loss is designated as Sleep latency; The time of righting reflex loss to the time that righting reflex begins to occur is designated as the length of one's sleep.The mensuration of the length of one's sleep must be carried out between the 11:00-15:00 in detection the same day.

2. result

2.1 the test sample medicinal liquid is on the preclinical impact of Sleep in Rats

After gavaging respectively the test sample medicinal liquid to rat, with the Sleep latency of rats in normal control group relatively (table 1), the Sleep latency of test sample medicinal liquid group rat obviously shortens (P＜0.01).

The preclinical comparison of table 14 group Sleep in Rats

One factor analysis of variance: * and Normal group compare, P＜0.01

2.2 the test sample medicinal liquid is on the impact of Sleep in Rats time

The comparison of table 24 group Sleep in Rats time

One factor analysis of variance: * and Normal group compare, P＜0.05

From experimental result can find out gavaged the test sample medicinal liquid after, the Sleep latency of rat shortens, prolong the length of one's sleep.This illustrates that this medicine proved recipe has definite sedative-hypnotic effect.

Medicine proved recipe of the present invention has formed comparatively clear and definite treatment curative effect through for several times fine setting.Has certain advantage with the clinical effect contrast test of existing Western medicine.

The used prescription of the present invention is not the simple combination for all kinds of medical materials, but screen on the basis of considering the character of various kinds of drug, taste, the property of medicine, incompatibility, and the prescription that forms according to a certain ratio, Each performs its own functions in each side, both organic cooperation was mutually promoted again.

Clinical efficacy

1. sample information

Use the party to control the insomniac over one hundred people 5 years, its unique curative effect makes most patients can both rapid healing more.Following table is extracted the typical clinical sample and is described.

2. criterion of therapeutical effect

Recovery from illness: Sleep latency, the actual length of one's sleep and awakening time number average return to the age bracket normal level, without sleep pressure, in the drug withdrawal three months without recurring.

Significantly: Sleep latency, the actual length of one's sleep and awakening time number average be improved significantly, without obvious sleep pressure.

Effectively: Sleep latency, the actual length of one's sleep and awakening time number average are necessarily improved, but the improvement degree is limited.

Invalid: insomnia is without any change or deterioration.

3. Therapeutic Method

Require to select proved recipe medicine of the present invention according to part by weight, adding approximately for the first time, the decoction of treble water gaging once leaches medicinal residues, for the second time add approximately that two times of weight decoctings boil once, decocted the elimination medicinal residues at every turn 25～30 minutes, merge medicine juice, taken three times a day, each 250ml.

4. clinical observation

5. model case

(1) leaf, man, 53 years old.The employee of Pujiang County, Zhejiang Province Pu Xi carrier.Leaf is introverted, and being unable to undergo language stimulates and pressure, and with the passing of time anxiety attack and insomnia are 6 years.Stable could the sleep of permanent dependence sleeping pill.Originally can also produce effect, afterwards gradually not effect of sleeping pill, effect is bad.Sometimes, one even can't fall asleep several evenings, and the state of an illness is more serious.Raise at the examination in hospital discovery first half of the year in 2012 liver transaminase, hospitalization had no and is clearly better in ten days.In July, 2012, upon somebody's introduction, we on probation.After taking three days, insomnia is clearly better, and after the week, checks, the transaminase is normal.After taking continuously 11 days afterwards, can sleep every night 6-7 hour, be clearly better.

(2) Wang, woman, 33 years old, Hua Qiao township, Pujiang County, Zhejiang Province Dong Tang people from village.Mental Subnormality 4 years once took multiple tranquilizer, and the state of an illness is repeatedly outbreak still.Use our decoction afterwards, serve on three doses, the state of an illness takes a turn for the better gradually, heals by withering reason.So far a year and a half has no recurrence, now takes part in the work.

(3) Yuan, woman, 32 years old, Hua Qiao township, Pujiang County, Zhejiang Province Dong Tang people from village.Insomniac more than 4 years, generally only slept every night two, three hours, sometimes sit up whole night, dizzy weak at ordinary times, the body void wind of easily being afraid of cold is met cool breeze and is easy to headache, and leucorrhea is many sometimes, and the waist abdomen is tired aches, and tongue fur is partially light white, thready and moderate pulse.Beginning decoction on March 5th, 2011 we take state of an illness recovery from illness after eight days, so far not recurrence.

(4) Liu, woman, 55 years old, Pujiang County, Zhejiang Province Electromechanical irrigation and drainage pumping station worker.In the past few years often insomnia, and there have gastropathy to have to be hidden painful, and pain is arranged during urine, examination in hospital liver and axillary lymph 0.5 to 1.2 size, white and greasy fur companion purple, the Sublingual arteries and veins is partially purple black.On October 23rd, 2008 beginning decoction we Chinese medicine, after five days, insomnia, urine heating, stomachache all take a favorable turn, and continue to take afterwards recovery from illness on the six afterwards.

(5) Huang, man, 16 years old, Hua Qiao township, Pujiang County, Zhejiang Province Dong Tang people from village.Attend school the junior middle school of county's emphasis, certain learning pressure is arranged, psychentonia causes and has a sleepless night about half a year.The formation health is afraid of cold, and face is partially pure, and tongue fur is partially yellow, thready pulse.Take this proved recipe since on February 11st, 2011, afterwards recovery from illness on the nine.

(6) Liu, women, 65 years old, Pujiang County, Zhejiang Province flower bridge village people.Lay awake all night five, six years, many being insomnia all night suffered untold misery at nightfall.Advise with our decoction.Take medicine and can fall asleep the very night in three division of day and night, taking medicine can be quiet sleeping after week, and the several years obstinate disease is fully recovered finally.

Specific embodiment

Embodiment one

(1) gets that Herba Mimosae Pudicae 25g, Herba Lespedezae Cuneatae 40g, Pinus massoniana Lamb 50g, Radix Et Caulis Acanthopanacis Senticosi 20g, wild goose swing lotus throne Herba pteridii latiusculi 20g, Herba Oxalidis Corniculatae 20g, Flos Albiziae 15g, Semen Ziziphi Spinosae 20g, Fructus Schisandrae Chinensis 15g, Radix Salviae Miltiorrhizae 15g, Rhizoma Corydalis 15g, Caulis Polygoni Multiflori 15g, Rhizoma Dioscoreae 20g, Radix Angelicae Sinensis 20g, Colla Corii Asini bead 12g, Radix Codonopsis 15g, Radix Polygoni Multiflori Preparata 15g, Semen Platycladi 12g, Herba Polygalae Japonicae 15g, Herba Epimedii 15g, Rhizoma Pinelliae Preparata 10g, Concha Ostreae 20g, Radix Et Rhizoma Nardostachyos 12g, Rhizoma Atractylodis Macrocephalae 15g, Herba Hyperici Japonici 15g, Radix Glycyrrhizae 90g places clean marmite.

(2) add the 1.7kg decocting for the first time and boil once, leach medicinal residues, add again the 1.1kg decocting and boil once, decocted 25～30 minutes at every turn, merge medicine juice.

(3) taken three times a day, minute early, middle and late each once, each 250ml.

Embodiment two

(1) gets that Herba Mimosae Pudicae 25g, Herba Lespedezae Cuneatae 50g, Pinus massoniana Lamb 50g, Radix Et Caulis Acanthopanacis Senticosi 25g, wild goose swing lotus throne Herba pteridii latiusculi 25g, Herba Oxalidis Corniculatae 25g, Flos Albiziae 20g, Semen Ziziphi Spinosae 25g, Fructus Schisandrae Chinensis 20g, Radix Salviae Miltiorrhizae 20g, Rhizoma Corydalis 20g, Caulis Polygoni Multiflori 20g, Rhizoma Dioscoreae 25g, Radix Angelicae Sinensis 25g, Colla Corii Asini bead 12g, Radix Codonopsis 20g, Radix Polygoni Multiflori Preparata 20g, Semen Platycladi 12g, Herba Polygalae Japonicae 20g, Herba Epimedii 20g, Rhizoma Pinelliae Preparata 12g, Concha Ostreae 20g, Radix Et Rhizoma Nardostachyos 12g, Rhizoma Atractylodis Macrocephalae 15g, Herba Hyperici Japonici 15g, Radix Glycyrrhizae 90g places clean marmite.

(2) add the 2.0kg decocting for the first time and boil once, leach medicinal residues, add again the 1.3kg decocting and boil once, decocted 25～30 minutes at every turn, merge medicine juice.

(3) taken three times a day, minute early, middle and late each once, each 250ml.

Embodiment three

(1) gets that Herba Mimosae Pudicae 25g, Herba Lespedezae Cuneatae 40g, Pinus massoniana Lamb 40g, Radix Et Caulis Acanthopanacis Senticosi 20g, wild goose swing lotus throne Herba pteridii latiusculi 20g, Herba Oxalidis Corniculatae 20g, Flos Albiziae 15g, Semen Ziziphi Spinosae 20g, Fructus Schisandrae Chinensis 20g, Radix Salviae Miltiorrhizae 15g, Rhizoma Corydalis 15g, Caulis Polygoni Multiflori 15g, Rhizoma Dioscoreae 25g, Radix Angelicae Sinensis 20g, Colla Corii Asini bead 10g, Radix Codonopsis 15g, Radix Polygoni Multiflori Preparata 15g, Semen Platycladi 10g, Herba Polygalae Japonicae 15g, Herba Epimedii 15g, Rhizoma Pinelliae Preparata 10g, Concha Ostreae 20g, Radix Et Rhizoma Nardostachyos 10g, Rhizoma Atractylodis Macrocephalae 15g, Herba Hyperici Japonici 15g, Radix Glycyrrhizae 90g places clean marmite.

(2) add the 1.7kg decocting for the first time and boil once, leach medicinal residues, add again the 1.1kg decocting and boil once, decocted 25～30 minutes at every turn, merge medicine juice.

(3) taken three times a day, minute early, middle and late each once, each 250ml.

Embodiment four

(1) gets that Herba Mimosae Pudicae 25g, Herba Lespedezae Cuneatae 40g, Pinus massoniana Lamb 40g, Radix Et Caulis Acanthopanacis Senticosi 22g, wild goose swing lotus throne Herba pteridii latiusculi 23g, Herba Oxalidis Corniculatae 23g, Flos Albiziae 15g, Semen Ziziphi Spinosae 21g, Fructus Schisandrae Chinensis 18g, Radix Salviae Miltiorrhizae 15g, Rhizoma Corydalis 15g, Caulis Polygoni Multiflori 18g, Rhizoma Dioscoreae 25g, Radix Angelicae Sinensis 20g, Colla Corii Asini bead 10g, Radix Codonopsis 20g, Radix Polygoni Multiflori Preparata 15g, Semen Platycladi 10g, Herba Polygalae Japonicae 17g, Herba Epimedii 16g, Rhizoma Pinelliae Preparata 11g, Concha Ostreae 23g, Radix Et Rhizoma Nardostachyos 10g, Rhizoma Atractylodis Macrocephalae 15g, Herba Hyperici Japonici 17g, Radix Glycyrrhizae 90g places clean marmite.

(2) add the 1.7kg decocting for the first time and boil once, leach medicinal residues, add again the 1.2kg decocting and boil once, decocted 25～30 minutes at every turn, merge medicine juice.

(3) taken three times a day, minute early, middle and late each once, each 250ml.

Claims (2)

1. the Chinese medicine proved recipe of a treatment of insomnia patients is characterized in that being comprised of according to weight portion following Chinese medicine:

40～50 parts of 25 parts of Herba Mimosae Pudicaes, Herba Lespedezae Cuneatae, Pinus massoniana Lamb, Radix Et Caulis Acanthopanacis Senticosi, wild goose swing 20～25 parts of lotus throne Herba pteridii latiusculis, Herba Oxalidis Corniculatae, Semen Ziziphi Spinosae, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Concha Ostreae, 15～20 parts of Flos Albiziaes, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Caulis Polygoni Multiflori, Radix Codonopsis, Radix Polygoni Multiflori Preparata, Herba Polygalae Japonicae, Herba Epimedii, the Rhizoma Atractylodis Macrocephalae, Poria cum Radix Pini, Herba Hyperici Japonici, Rhizoma Pinelliae Preparata, Colla Corii Asini bead, Semen Platycladi, 10～12 parts of Radix Et Rhizoma Nardostachyos, 90 parts in Radix Glycyrrhizae.

2. Chinese prescription as claimed in claim 1, its optimum weight portion proportioning is:

25 parts of Herba Mimosae Pudicaes, 40 parts of Herba Lespedezae Cuneatae, 50 parts of Pinus massoniana Lamb, 20 parts of Radix Et Caulis Acanthopanacis Senticosis, wild goose swings 20 parts of lotus throne Herba pteridii latiusculis, 20 parts of Herba Oxalidis Corniculataes, 20 parts of Semen Ziziphi Spinosaes, 20 parts of Rhizoma Dioscoreaes, 20 parts of Radix Angelicae Sinensis, 20 parts of Concha Ostreaes, 15 parts of Flos Albiziaes, 15 parts of Fructus Schisandrae Chinensis, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Corydalis, 15 parts of Caulis Polygoni Multiflori, 15 parts of Radix Codonopsis, 15 parts of Radix Polygoni Multiflori Preparata, 15 parts of Herba Polygalae Japonicae, 15 parts of Herba Epimedii, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Poria cum Radix Pinis, 15 parts of Herba Hyperici Japonici, 10 parts of Rhizoma Pinelliae Preparata, 12 parts of Colla Corii Asini beads, 12 parts of Semen Platycladi, 12 parts of Radix Et Rhizoma Nardostachyos, 90 parts in Radix Glycyrrhizae.