CN108578562A - It is a kind of to be used to treat Chinese medicine composition of leukaemia and preparation method thereof - Google Patents
It is a kind of to be used to treat Chinese medicine composition of leukaemia and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compositions for treating leukaemia, are prepared by the raw material of following parts by weight:10 20 parts of Radix Astragali, 10 20 parts of Radix Angelicae Sinensis, 10 30 parts of Japanese polygala, 10 30 parts of nettle, 10 30 parts of the Fructus Sophorae, 10 20 parts of the root of Dahurain angelica, 5 10 parts of indigo naturalis, 5 10 parts of fritillaria thunbergii, 10 15 parts of radix salviae miltiorrhizae, 10 15 parts of sweet wormwood, 10 20 parts of Radix Codonopsis, 5 10 parts of tortoise-shell glue, 10 20 parts of prepared rehmannia root, 10 20 parts of tree peony root, bright and beautiful 10 15 parts of vanilla, 40 60 parts of psoralea corylifolia, 20 30 parts of Chinese fanpalm seed.The present invention has clearing heat and detoxicating, promoting blood circulation and removing blood stasis, righting and other effects of getting rid of evils, and can adjust immune function of human body, improves natural killer cells and LAK activity, the effect for increasing anti-leukocythemia ability.
Description
Technical field
The present invention relates to field of traditional Chinese, and in particular to a kind of Chinese medicine composition and its preparation for treating leukaemia
Method.
Background technology
Leukaemia is the malignant disease of hematopoietic tissue, also known as " leukemia ".Its main feature is that having in marrow and other hematopoietic tissues
A large amount of cytodes unlimitedly hyperplasia, and enter peripheral blood, the kernel of normal plasma cell is obviously adsorbed, which occupies youth
First place in people's malignant disease, original virus may be the negative sense hyperblastosis of nerve, and there are many more the mines of factor such as food
Object radioactivity poisons the co-factor that (benzene etc.) or drug variation, heredodiathesis etc. may be pathogenic.Not according to leukaemia cell
The natural history of ripe degree and leukaemia, is divided into acute and chronic two major classes.
Traditional Chinese medicine think the morbidity of leukaemia mostly become estranged in deficient, negative and positive interior, internal organs weakness on the basis of warm poison it is evil
Deng in an opponent's defence and caused by people.1, vital essence internal weakness is this pathogenetic internal cause, in close relations with liver and spleen kidney.Feelings will is unsmooth, stagnation of liver qi,
It is qi-blood disharmony, imbalance of yin and yang.Long-term partial eclipse and cause spleen deficiency, no resource of generating and transforming QI and blood is more apparent in child patient.2, warm poison
This evil disease especially acute leukemia has onset anxious, the features such as quickly growing, be dangerously ill, be easy to recurrence and prognosis mala,
Therefore the malicious heresy of warm is this pathogenetic important external cause.
Invention content
The purpose of the present invention is to provide a kind of Chinese medicine compositions and preparation method thereof for treating leukaemia.
To achieve the above object, the technical solution that the present invention takes is:
A kind of Chinese medicine composition for treating leukaemia is prepared by the raw material of following parts by weight:
10-20 parts of Radix Astragali, 10-20 parts of Radix Angelicae Sinensis, 10-30 parts of Japanese polygala, 10-30 parts of nettle, 10-30 parts of the Fructus Sophorae, root of Dahurain angelica 10-
20 parts, 5-10 parts of indigo naturalis, 5-10 parts of fritillaria thunbergii, 10-15 parts of radix salviae miltiorrhizae, 10-15 parts of sweet wormwood, 10-20 parts of Radix Codonopsis, tortoise-shell glue 5-10
Part, 10-20 parts of prepared rehmannia root, 10-20 parts of tree peony root, bright and beautiful 10-15 parts of vanilla, 40-60 parts of psoralea corylifolia, 20-30 parts of Chinese fanpalm seed.
Preferably, it is prepared by the raw material of following parts by weight:
10 parts of Radix Astragali, 10 parts of Radix Angelicae Sinensis, 10 parts of Japanese polygala, 10 parts of nettle, 10 parts of the Fructus Sophorae, 10 parts of the root of Dahurain angelica, 5 parts of indigo naturalis, bulb of thunberg fritillary
5 parts female, 10 parts of radix salviae miltiorrhizae, 10 parts of sweet wormwood, 10 parts of Radix Codonopsis, 5 parts of tortoise-shell glue, 10 parts of prepared rehmannia root, 10 parts of tree peony root, bright and beautiful vanilla 10
Part, 40 parts of psoralea corylifolia, 20 parts of Chinese fanpalm seed.
Preferably, it is prepared by the raw material of following parts by weight:
20 parts of Radix Astragali, 20 parts of Radix Angelicae Sinensis, 30 parts of Japanese polygala, 30 parts of nettle, 30 parts of the Fructus Sophorae, 20 parts of the root of Dahurain angelica, 10 parts of indigo naturalis, bulb of thunberg fritillary
10 parts female, 15 parts of radix salviae miltiorrhizae, 15 parts of sweet wormwood, 20 parts of Radix Codonopsis, 10 parts of tortoise-shell glue, 20 parts of prepared rehmannia root, 20 parts of tree peony root, bright and beautiful vanilla 15
Part, 60 parts of psoralea corylifolia, 30 parts of Chinese fanpalm seed.
Preferably, it is prepared by the raw material of following parts by weight:
15 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis, 20 parts of Japanese polygala, 20 parts of nettle, 20 parts of the Fructus Sophorae, 15 parts of the root of Dahurain angelica, 7.5 parts of indigo naturalis, Zhejiang
7.5 parts of fritillaria, 12.5 parts of radix salviae miltiorrhizae, 12.5 parts of sweet wormwood, 15 parts of Radix Codonopsis, 7.5 parts of tortoise-shell glue, 15 parts of prepared rehmannia root, 15 parts of tree peony root,
12.5 parts of bright and beautiful vanilla, 50 parts of psoralea corylifolia, 25 parts of Chinese fanpalm seed.
Preferably, it is prepared by the raw material of following parts by weight:
13 parts of Radix Astragali, 13 parts of Radix Angelicae Sinensis, 18 parts of Japanese polygala, 18 parts of nettle, 18 parts of the Fructus Sophorae, 13 parts of the root of Dahurain angelica, 6 parts of indigo naturalis, bulb of thunberg fritillary
6 parts female, 11 parts of radix salviae miltiorrhizae, 11 parts of sweet wormwood, 13 parts of Radix Codonopsis, 6 parts of tortoise-shell glue, 13 parts of prepared rehmannia root, 13 parts of tree peony root, bright and beautiful vanilla 11
Part, 48 parts of psoralea corylifolia, 23 parts of Chinese fanpalm seed.
Preferably, it is prepared by the raw material of following parts by weight:
17 parts of Radix Astragali, 17 parts of Radix Angelicae Sinensis, 22 parts of Japanese polygala, 22 parts of nettle, 22 parts of the Fructus Sophorae, 17 parts of the root of Dahurain angelica, 9 parts of indigo naturalis, bulb of thunberg fritillary
9 parts female, 14 parts of radix salviae miltiorrhizae, 14 parts of sweet wormwood, 17 parts of Radix Codonopsis, 9 parts of tortoise-shell glue, 17 parts of prepared rehmannia root, 17 parts of tree peony root, bright and beautiful vanilla 14
Part, 52 parts of psoralea corylifolia, 27 parts of Chinese fanpalm seed.
The present invention also provides a kind of above-mentioned preparation methods for treating the Chinese medicine composition of leukaemia, including walk as follows
Suddenly:
S1, each component is weighed by above-mentioned formula;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, are first passed through nitrogen to steam-explosion jar internal pressure
Power is 0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, is steamed
After vapour explosion treatment 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%,
25-35 DEG C of temperature is kept, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
It is S3, Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, brocade is fragrant
After grass, psoralea corylifolia, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the second that the volumetric concentration of 6 times of amounts is 75~85% is added
After alcoholic solution impregnates 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
The invention has the advantages that:
The present invention has clearing heat and detoxicating, promoting blood circulation and removing blood stasis, righting and other effects of getting rid of evils, and can adjust immune function of human body, improves
Natural killer cells and LAK activity, the effect for increasing anti-leukocythemia ability.
Specific implementation mode
In order to make objects and advantages of the present invention be more clearly understood, the present invention is carried out with reference to embodiments further
It is described in detail.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to limit this hair
It is bright.
Embodiment 1
A kind of preparation method for treating the Chinese medicine composition of leukaemia includes the following steps:
S1, it weighs by weight:10 parts of Radix Astragali, 10 parts of Radix Angelicae Sinensis, 10 parts of Japanese polygala, 10 parts of nettle, 10 parts of the Fructus Sophorae, the root of Dahurain angelica 10
Part, 5 parts of indigo naturalis, 5 parts of fritillaria thunbergii, 10 parts of radix salviae miltiorrhizae, 10 parts of sweet wormwood, 10 parts of Radix Codonopsis, 5 parts of tortoise-shell glue, 10 parts of prepared rehmannia root, tree peony root
10 parts, bright and beautiful 10 parts of vanilla, 40 parts of psoralea corylifolia, 20 parts of Chinese fanpalm seed;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, are first passed through nitrogen to steam-explosion jar internal pressure
Power is 0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, is steamed
After vapour explosion treatment 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%,
25-35 DEG C of temperature is kept, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
It is S3, Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, brocade is fragrant
After grass, psoralea corylifolia, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the second that the volumetric concentration of 6 times of amounts is 75~85% is added
After alcoholic solution impregnates 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
Embodiment 2
A kind of preparation method for treating the Chinese medicine composition of leukaemia includes the following steps:
S1, it weighs by weight:20 parts of Radix Astragali, 20 parts of Radix Angelicae Sinensis, 30 parts of Japanese polygala, 30 parts of nettle, 30 parts of the Fructus Sophorae, the root of Dahurain angelica 20
It is part, 10 parts of indigo naturalis, 10 parts of fritillaria thunbergii, 15 parts of radix salviae miltiorrhizae, 15 parts of sweet wormwood, 20 parts of Radix Codonopsis, 10 parts of tortoise-shell glue, 20 parts of prepared rehmannia root, male
20 parts of red root, bright and beautiful 15 parts of vanilla, 60 parts of psoralea corylifolia, 30 parts of Chinese fanpalm seed;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, are first passed through nitrogen to steam-explosion jar internal pressure
Power is 0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, is steamed
After vapour explosion treatment 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%,
25-35 DEG C of temperature is kept, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
It is S3, Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, brocade is fragrant
After grass, psoralea corylifolia, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the second that the volumetric concentration of 6 times of amounts is 75~85% is added
After alcoholic solution impregnates 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
Embodiment 3
A kind of preparation method for treating the Chinese medicine composition of leukaemia includes the following steps:
S1, it weighs by weight:15 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis, 20 parts of Japanese polygala, 20 parts of nettle, 20 parts of the Fructus Sophorae, the root of Dahurain angelica 15
Part, 7.5 parts of indigo naturalis, 7.5 parts of fritillaria thunbergii, 12.5 parts of radix salviae miltiorrhizae, 12.5 parts of sweet wormwood, 15 parts of Radix Codonopsis, 7.5 parts of tortoise-shell glue, prepared rehmannia root
15 parts, 15 parts of tree peony root, bright and beautiful 12.5 parts of vanilla, 50 parts of psoralea corylifolia, 25 parts of Chinese fanpalm seed;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, are first passed through nitrogen to steam-explosion jar internal pressure
Power is 0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, is steamed
After vapour explosion treatment 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%,
25-35 DEG C of temperature is kept, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
It is S3, Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, brocade is fragrant
After grass, psoralea corylifolia, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the second that the volumetric concentration of 6 times of amounts is 75~85% is added
After alcoholic solution impregnates 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
Embodiment 4
A kind of preparation method for treating the Chinese medicine composition of leukaemia includes the following steps:
S1, it weighs by weight:13 parts of Radix Astragali, 13 parts of Radix Angelicae Sinensis, 18 parts of Japanese polygala, 18 parts of nettle, 18 parts of the Fructus Sophorae, the root of Dahurain angelica 13
Part, 6 parts of indigo naturalis, 6 parts of fritillaria thunbergii, 11 parts of radix salviae miltiorrhizae, 11 parts of sweet wormwood, 13 parts of Radix Codonopsis, 6 parts of tortoise-shell glue, 13 parts of prepared rehmannia root, tree peony root
13 parts, bright and beautiful 11 parts of vanilla, 48 parts of psoralea corylifolia, 23 parts of Chinese fanpalm seed;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, are first passed through nitrogen to steam-explosion jar internal pressure
Power is 0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, is steamed
After vapour explosion treatment 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%,
25-35 DEG C of temperature is kept, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
It is S3, Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, brocade is fragrant
After grass, psoralea corylifolia, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the second that the volumetric concentration of 6 times of amounts is 75~85% is added
After alcoholic solution impregnates 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
Embodiment 5
A kind of preparation method for treating the Chinese medicine composition of leukaemia includes the following steps:
S1, it weighs by weight:17 parts of Radix Astragali, 17 parts of Radix Angelicae Sinensis, 22 parts of Japanese polygala, 22 parts of nettle, 22 parts of the Fructus Sophorae, the root of Dahurain angelica 17
Part, 9 parts of indigo naturalis, 9 parts of fritillaria thunbergii, 14 parts of radix salviae miltiorrhizae, 14 parts of sweet wormwood, 17 parts of Radix Codonopsis, 9 parts of tortoise-shell glue, 17 parts of prepared rehmannia root, tree peony root
17 parts, bright and beautiful 14 parts of vanilla, 52 parts of psoralea corylifolia, 27 parts of Chinese fanpalm seed;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, are first passed through nitrogen to steam-explosion jar internal pressure
Power is 0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, is steamed
After vapour explosion treatment 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%,
25-35 DEG C of temperature is kept, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
It is S3, Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, brocade is fragrant
After grass, psoralea corylifolia, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the second that the volumetric concentration of 6 times of amounts is 75~85% is added
After alcoholic solution impregnates 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
Test example
100 patients are received, the Chinese medicine preparation prepared using embodiment 3, take medicine 5g every time, 3 times a day, continuous to take medicine
6 months, wherein the physiochemical indice items numerical value of 82 patients reaches normal value, remaining 16 patient was slightly less than just except blood platelet value
Constant value is in good condition hereinafter, other indices numerical stabilities, is belonging to recovery from illness scope, only two Platelets always below just
Constant value, other indices numerical stabilities.Statistics is it is found that the present invention is used to treat hemopathic Chinese medicine composition to hemopathic
Cure rate is efficient up to 100% up to 82%.Wherein, curative effect judging standard is:Effectively:Symptom mitigate, whole blood cells, red blood cell,
Leucocyte reaches normal value, and the only insufficient normal value of one, blood platelet, integrality is good;It cures:Symptom disappears, physiochemical indice
Every numerical value reaches normal value.
Toxic side effect
4 have slight gastrointestinal reaction in 100 patients for the treatment of group, periodic review hepatic and renal function in all patients follow-up,
Only 3 there are AST raisings, are down to after being treated using hepatic normally, can adhere to treating.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the principle of the present invention, it can also make several improvements and retouch, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (7)
1. a kind of Chinese medicine composition for treating leukaemia, it is characterised in that:It is prepared by the raw material of following parts by weight:
10-20 parts of Radix Astragali, 10-20 parts of Radix Angelicae Sinensis, 10-30 parts of Japanese polygala, 10-30 parts of nettle, 10-30 parts of the Fructus Sophorae, root of Dahurain angelica 10-20
Part, 5-10 parts of indigo naturalis, 5-10 parts of fritillaria thunbergii, 10-15 parts of radix salviae miltiorrhizae, 10-15 parts of sweet wormwood, 10-20 parts of Radix Codonopsis, tortoise-shell glue 5-10
Part, 10-20 parts of prepared rehmannia root, 10-20 parts of tree peony root, bright and beautiful 10-15 parts of vanilla, 40-60 parts of psoralea corylifolia, 20-30 parts of Chinese fanpalm seed.
2. a kind of Chinese medicine composition for treating leukaemia as described in claim 1, it is characterised in that:By following parts by weight
Raw material be prepared:
10 parts of Radix Astragali, 10 parts of Radix Angelicae Sinensis, 10 parts of Japanese polygala, 10 parts of nettle, 10 parts of the Fructus Sophorae, 10 parts of the root of Dahurain angelica, 5 parts of indigo naturalis, fritillaria thunbergii 5
Part, bright and beautiful 10 parts of vanilla, is mended 10 parts of radix salviae miltiorrhizae, 10 parts of sweet wormwood, 10 parts of Radix Codonopsis, 5 parts of tortoise-shell glue, 10 parts of prepared rehmannia root, 10 parts of tree peony root
40 parts of bone fat, 20 parts of Chinese fanpalm seed.
3. a kind of Chinese medicine composition for treating leukaemia as described in claim 1, it is characterised in that:By following parts by weight
Raw material be prepared:
20 parts of Radix Astragali, 20 parts of Radix Angelicae Sinensis, 30 parts of Japanese polygala, 30 parts of nettle, 30 parts of the Fructus Sophorae, 20 parts of the root of Dahurain angelica, 10 parts of indigo naturalis, fritillaria thunbergii 10
Part, 15 parts of radix salviae miltiorrhizae, 15 parts of sweet wormwood, 20 parts of Radix Codonopsis, 10 parts of tortoise-shell glue, 20 parts of prepared rehmannia root, 20 parts of tree peony root, bright and beautiful 15 parts of vanilla,
60 parts of psoralea corylifolia, 30 parts of Chinese fanpalm seed.
4. a kind of Chinese medicine composition for treating leukaemia as described in claim 1, it is characterised in that:By following parts by weight
Raw material be prepared:
15 parts of Radix Astragali, 15 parts of Radix Angelicae Sinensis, 20 parts of Japanese polygala, 20 parts of nettle, 20 parts of the Fructus Sophorae, 15 parts of the root of Dahurain angelica, 7.5 parts of indigo naturalis, fritillaria thunbergii
7.5 parts, 12.5 parts of radix salviae miltiorrhizae, 12.5 parts of sweet wormwood, 15 parts of Radix Codonopsis, 7.5 parts of tortoise-shell glue, 15 parts of prepared rehmannia root, 15 parts of tree peony root, brocade it is fragrant
12.5 parts of grass, 50 parts of psoralea corylifolia, 25 parts of Chinese fanpalm seed.
5. a kind of Chinese medicine composition for treating leukaemia as described in claim 1, it is characterised in that:By following parts by weight
Raw material be prepared:
13 parts of Radix Astragali, 13 parts of Radix Angelicae Sinensis, 18 parts of Japanese polygala, 18 parts of nettle, 18 parts of the Fructus Sophorae, 13 parts of the root of Dahurain angelica, 6 parts of indigo naturalis, fritillaria thunbergii 6
Part, bright and beautiful 11 parts of vanilla, is mended 11 parts of radix salviae miltiorrhizae, 11 parts of sweet wormwood, 13 parts of Radix Codonopsis, 6 parts of tortoise-shell glue, 13 parts of prepared rehmannia root, 13 parts of tree peony root
48 parts of bone fat, 23 parts of Chinese fanpalm seed.
6. a kind of Chinese medicine composition for treating leukaemia as described in claim 1, it is characterised in that:By following parts by weight
Raw material be prepared:
17 parts of Radix Astragali, 17 parts of Radix Angelicae Sinensis, 22 parts of Japanese polygala, 22 parts of nettle, 22 parts of the Fructus Sophorae, 17 parts of the root of Dahurain angelica, 9 parts of indigo naturalis, fritillaria thunbergii 9
Part, bright and beautiful 14 parts of vanilla, is mended 14 parts of radix salviae miltiorrhizae, 14 parts of sweet wormwood, 17 parts of Radix Codonopsis, 9 parts of tortoise-shell glue, 17 parts of prepared rehmannia root, 17 parts of tree peony root
52 parts of bone fat, 27 parts of Chinese fanpalm seed.
7. a kind of preparation method for treating the Chinese medicine composition of leukaemia, it is characterised in that:Include the following steps:
S1, each component is weighed by claim 1-6 any one of them formulas;
S2, the indigo naturalis weighed, sweet wormwood, prepared rehmannia root, tree peony root are placed in steam-explosion jar, being first passed through nitrogen to steam explosion pressure inside the tank is
0.7-1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through steam to steam explosion pressure inside the tank rapidly, and steam is quick-fried
After tear manages 0.8-2.8min, after freeze-drying, according to the ratio microbe inoculation leavening of inoculum concentration 1.5-1.7%, keep
25-35 DEG C of temperature, after fermenting 36-54 hours, high-temperature sterilization obtains zymotic fluid;
S3, by Radix Astragali, Radix Angelicae Sinensis, Japanese polygala, nettle, the Fructus Sophorae, the root of Dahurain angelica, fritillaria thunbergii, radix salviae miltiorrhizae, Radix Codonopsis, tortoise-shell glue, bright and beautiful vanilla, mend
After bone fat, Chinese fanpalm seed are placed in flash extracter processing 30-60S, the ethanol solution that the volumetric concentration of 6 times of amounts is 75~85% is added
After impregnating 2~3h, after handling 30~60S at 30~50 DEG C, ethyl alcohol is recycled, filtering obtains extracting solution;
S4, it after the zymotic fluid of gained and extracting solution are mixed evenly, is freeze-dried to get composition.
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CN109045194A (en) * | 2018-09-29 | 2018-12-21 | 西安医学院第附属医院 | Chinese medicine composition and preparation method thereof for treating acute leukemia |
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