CN104189296A - Traditional Chinese medicine oral solution for treating jaundice of pigs and preparation method thereof - Google Patents
Traditional Chinese medicine oral solution for treating jaundice of pigs and preparation method thereof Download PDFInfo
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- CN104189296A CN104189296A CN201410419794.5A CN201410419794A CN104189296A CN 104189296 A CN104189296 A CN 104189296A CN 201410419794 A CN201410419794 A CN 201410419794A CN 104189296 A CN104189296 A CN 104189296A
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Abstract
The invention relates to a traditional Chinese medicine oral solution for treating jaundice of pigs and a preparation method thereof. The oral solution is prepared from herba artemisiae scopariae, rhizoma atractylodis macrocephalae, poria cocos, rhizoma alismatis, cassia twig, grifola, rheum officinale, cape jasmine, licorice root, radix paeoniae rubra and cortex phellodendri. The traditional Chinese medicine composition is an oral solution and is prepared by the following steps: (1) grinding the traditional Chinese medicines into particles of 60-80 meshes, weighing according to the amount of the prescription, and mixing in a three-dimensional manner to obtain traditional Chinese medicine powder; (2) respectively putting the mixed traditional Chinese medicine powder and 300-600 parts of water into an extraction pot, and soaking for 5-20 hours; (3) heating to 40-100 DEG C, and extracting for 10-15 hours; (4) filtering and collecting the medicinal liquid; (5) continuously adding 300-600 parts of water into the remained medicine residues, and extracting at 40-100 DEG C for 10-15 hours; (6) filtering to remove the medicine residues, combining the twice extracting liquids, concentrating at reduced pressure at 30-70 DEG C until the liquid is 10-20 percent of the original volume; and (7) filling each bottle with 250ml of the medicinal liquid to obtain a finished product. The traditional Chinese medicine oral solution is capable of effectively treating jaundice of pigs, and has the cure rate over 90 percent. The prescription has the effects of clearing heat and removing jaundice, clearing damp and promoting diuresis, and purging pathogenic fire and removing toxicity.
Description
Technical field
The invention belongs to herbal medicine formulation art, especially a kind of Chinese medicine oral liquid for the treatment of pig jaundice and preparation method thereof.
Background technology
Pig jaundice is exactly because Disorders of bilirubin metabolism shows sclera, mucosa, skin and some histoorgan xanthochromias, makes the each tissue of body present yellow a kind of disease.Jaundice is not disease independently, and it is a kind of common sympton of following or be revealed in various diseases process.The body inner blood bilirubin concentration of pig increases but does not manifest clinically xanthochromia Signs, and people are called latent jaundice.Caused the jaundice symptom of groupment disease by various paathogenic factors, be called groupment jaundice.Jaundice has the meaning of particular importance in clinical diagnosis.
Pig jaundice gets to the bottom of sb.'s illness and is divided into: 1, exogenous jaundice, exogenous jaundice is called again yellow fat disease, is singlely ediblely to contain a large amount of flavochrome feedstuffs and cause because pig is long-term.2, hemolytic jaundice, hemolytic jaundice is because some infectious disease, Blood protozoan, hemoglobin disease, haemolysis thing are poisoning, forage poisoning etc. is destroyed hemocyte, blood mesobilirubin rolls up, and bile can not normally be drained, and part bile enters due to blood.3, hepatocellular jaundice, hepatocellular jaundice is owing to suffering from infectious disease or poisoning, making due to liver cell generation obstacle.The infectious disease such as ancylostomiasis, influenza, putrid and deteriorated feedstuff or noxious substance, as chemical substances such as carbon tetrachloride, hexachlorethane, arsenic, hydrargyrum, aluminum, can cause liver cell jaundice.4, mechanical jaundice, mechanical jaundice is that bile excretion is subject to obstacle due to bile duct generation mechanical obstruction, and bile is entered due to blood.Parasite (ascarid, distoma hepaticum etc.), duodenum mucositis and various hepatic disease all can cause mechanical jaundice.
Clinical manifestation is that sick pig appetite is depressed, tired, happiness is sleeping.Usually vomiting, thirsty, constipation dysentery afterwards, an eye conjunctiva is yellow, and it is yellow that skin, mucosa, urine and milk etc. are also, and skin is itched.The sick pig that suffers from mechanical jaundice, feces is yellow or Lycoperdon polymorphum Vitt, foul smelling taste.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, a kind of good effect, no drug residue, safe and reliable treatment pig jaundice Chinese medicine oral liquid are provided.
Another technical problem that the present invention will solve is: a kind of Chinese medicine formula for the treatment of pig jaundice is provided.
Another technical problem that the present invention will solve is: the preparation method that the oral liquid formulations of above-mentioned pig Chinese medicine composition is provided.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of pig jaundice, is prepared from by the raw material of following mass fraction: Herba Artemisiae Scopariae 20-40 part, Rhizoma Atractylodis Macrocephalae 20-40 part, Poria 20-40 part, Rhizoma Alismatis 20-40 part, Ramulus Cinnamomi 20-40 part, Polyporus 20-40 part, Radix Et Rhizoma Rhei 20-40 part, Fructus Gardeniae 10-20 part, Radix Paeoniae Rubra 20-40 part, Cortex Phellodendri 20-40 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows:
30 parts of Herba Artemisiae Scopariaes, 40 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts, Poria, 30 parts of Rhizoma Alismatis, 20 parts of Ramulus Cinnamomi, 30 parts of Polyporus, 40 parts of Radix Et Rhizoma Rhei, 20 parts of Fructus Gardeniaes, 20 parts, Radix Glycyrrhizae, 30 parts of Radix Paeoniae Rubra, 30 parts of Cortex Phellodendris.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form that contains or do not contain pharmaceutic adjuvant.
Further, the preparation method of the oral liquid formulations of said composition is: Chinese medicine powder is broken to 60-80 order by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder and 300-600 part water are put into respectively in extraction pot, soaked 5-20 hour; (3) be heated to 40-100 DEG C and extract 10-15 hour; (4) filter and collect medicinal liquid; (5) last medicinal residues continue to add 300-600 part water, and 40-100 DEG C is extracted 10-15 hour; (6) remove by filter medicinal residues, merge extracted twice liquid, 30-70 DEG C is evaporated to original volume 10%-20%; (7) fill becomes bottle, and every bottle of 250ml, gets product.
Advantage and good effect that the present invention has are:
(1) the present invention is according to tcm theory, and science compatibility has retained the combined effect of Chinese medicinal formulae determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, through clinical verification determined curative effect, is a kind of green veterinary drug of nuisanceless, no drug residue.
(2) Chinese medicine ingredients that the present invention contains can effectively be treated pig jaundice, and cure rate can reach more than 90%.This prescription has the effect of heat clearing away jaundice eliminating, promoting diuresis to eliminate damp pathogen, eliminating fire and detoxication.
(3) pharmacology of the each raw material of Chinese medicine of the present invention is:
Herba Artemisiae Scopariae: clearing away heat-damp and promoting diuresis, jaundice eliminating.
The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, dampness diuretic.
Poria: promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming.
Rhizoma Alismatis: diuretic, eliminating dampness by diuresis, expel the heat-evil.
Ramulus Cinnamomi: promoting the flow of QI-blood by warming the meridian.
Polyporus: warming YANG, promoting diuresis to eliminate damp pathogen.
Radix Et Rhizoma Rhei: clearing away damp-heat, purging fire and cooling blood, removing toxic substances.
Radix Glycyrrhizae: heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.
Fructus Gardeniae: clearing away heat and cooling blood, arresting convulsion removing toxic substances.
Cortex Phellodendri: heat clearing and damp drying, eliminating fire and detoxication, bring down a fever except steam.
Radix Paeoniae Rubra: clearing away heat and cooling blood, eliminating stasis to stop pain.
According to theory of Chinese medical science, the reason of jaundice is that suffocating of liver and gall function is hindered by hot and suffocating, due to letting out down nowhere, works as removing damp-heat, diuretic.By removing body heat, diuresis, jaundice is walked with urine.In we, Herba Artemisiae Scopariae is monarch drug, gets effect of its heat clearing away jaundice eliminating.Polyporus, Poria, Rhizoma Alismatis, the permeable dampness removing of Rhizoma Atractylodis Macrocephalae four Chinese medicine, tonneau water channel, thereby the jaundice of alluvial in discharge body, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, adjusts with the logical of dredging water passages.Radix Et Rhizoma Rhei, Cortex Phellodendri, Fructus Gardeniae, Radix Paeoniae Rubra four Chinese medicine clearing away heat and cooling blood, eliminating fire and detoxication, affect the hot and suffocating of suffocating of liver and gall in removing body.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Thereby reach relieving exterior-interior syndrome, jaundice eliminating is removed pathogenic heat in body simultaneously.
Detailed description of the invention
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
A Chinese medicine oral liquid for treatment pig jaundice, the parts by weight of each raw material are as follows: 30 parts of Herba Artemisiae Scopariaes, 40 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts, Poria, 30 parts of Rhizoma Alismatis, 20 parts of Ramulus Cinnamomi, 30 parts of Polyporus, 40 parts of Radix Et Rhizoma Rhei, 20 parts of Fructus Gardeniaes, 20 parts, Radix Glycyrrhizae, 30 parts of Radix Paeoniae Rubra, 30 parts of Cortex Phellodendris.Its preparation method is: Chinese medicine powder is broken to 80 orders by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder and 500 parts of water are put in extraction pot, soaked 10 hours; (3) being heated to 100 DEG C extracts 12 hours; (4) filter and collect medicinal liquid; (5) last medicinal residues continue to add 500 parts of water, and 100 DEG C are extracted 12 hours; (6) remove by filter medicinal residues, merge extracted twice liquid, 60 DEG C are evaporated to original volume 10%; (7) fill becomes bottle, and every bottle of 250ml, gets product.
Embodiment 2
A Chinese medicine oral liquid for treatment pig jaundice, the parts by weight of each raw material are as follows: 25 parts of Herba Artemisiae Scopariaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Poria, 30 parts of Rhizoma Alismatis, 30 parts of Ramulus Cinnamomi, 20 parts of Polyporus, 40 parts of Radix Et Rhizoma Rhei, 10 parts of Fructus Gardeniaes, 20 parts, Radix Glycyrrhizae, 30 parts of Radix Paeoniae Rubra, 30 parts of Cortex Phellodendris.Its preparation method is: Chinese medicine powder is broken to 80 orders by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder and 500 parts of water are put in extraction pot, soaked 10 hours; (3) being heated to 100 DEG C extracts 12 hours; (4) filter and collect medicinal liquid; (5) last medicinal residues continue to add 500 parts of water, and 100 DEG C are extracted 12 hours; (6) remove by filter medicinal residues, merge extracted twice liquid, 60 DEG C are evaporated to original volume 10%; (7) fill becomes bottle, and every bottle of 250ml, gets product
Embodiment 3
A Chinese medicine oral liquid for treatment pig jaundice, the parts by weight of each raw material are as follows: 40 parts of Herba Artemisiae Scopariaes, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Poria, 20 parts of Rhizoma Alismatis, 20 parts of Ramulus Cinnamomi, 30 parts of Polyporus, 40 parts of Radix Et Rhizoma Rhei, 15 parts of Fructus Gardeniaes, 30 parts, Radix Glycyrrhizae, 40 parts of Radix Paeoniae Rubra, 30 parts of Cortex Phellodendris.Its preparation method is: Chinese medicine powder is broken to 80 orders by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder and 500 parts of water are put in extraction pot, soaked 10 hours; (3) being heated to 100 DEG C extracts 12 hours; (4) filter and collect medicinal liquid; (5) last medicinal residues continue to add 500 parts of water, and 100 DEG C are extracted 12 hours; (6) remove by filter medicinal residues, merge extracted twice liquid, 60 DEG C are evaporated to original volume 10%; (7) fill becomes bottle, and every bottle of 250ml, gets product
Clinical trial
Experimental example:
Pig farm, Jilin, 30000 of market pigs, fall ill 5000.The sick pig appetite of clinical manifestation is depressed, tired, happiness is sleeping, vomiting, constipation, and an eye conjunctiva is yellow, and it is yellow that skin, urine are.Through being accredited as pig jaundice.To wherein 4000 use embodiment 1 obtained products.100 kilograms of every bottle of spices, once a day, treat five days.Medication the second remission, spirit takes a turn for the better, and feed intake increases.Within the 3rd day, skin starts jaundice eliminating, and urine quantity increases, and stool is normal.Within the 5th day, jumpbogroup recovers normal, without jaundice clinical symptoms.After drug withdrawal, do not occur repeatedly.Cure rate reaches 95%, without dead.The sick pig of a small amount of severe disease continues medication three days, except a death, all cures.Another 1000 use cefquinome to coordinate diuretic furosemide, treat continuously cure rate 75%, dead 33 seven days.
Experimental results show that the obtained product of embodiment 1 subtracts effect fast, determined curative effect, is difficult for repeatedly.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiment according to limited range, therefore in the variation and the amendment that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (9)
1. treat Chinese medicine oral liquid of pig jaundice and preparation method thereof for one kind, it is characterized in that: the raw material by following mass fraction is prepared from: Herba Artemisiae Scopariae 20-40 part, Rhizoma Atractylodis Macrocephalae 20-40 part, Poria 20-40 part, Rhizoma Alismatis 20-40 part, Ramulus Cinnamomi 20-40 part, Polyporus 20-40 part, Radix Et Rhizoma Rhei 20-40 part, Fructus Gardeniae 10-20 part, Radix Paeoniae Rubra 20-40 part, Cortex Phellodendri 20-40 part.
2. the Chinese medicine oral liquid for the treatment of pig jaundice according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
30 parts of Herba Artemisiae Scopariaes, 40 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts, Poria, 30 parts of Rhizoma Alismatis, 20 parts of Ramulus Cinnamomi, 30 parts of Polyporus, 40 parts of Radix Et Rhizoma Rhei, 20 parts of Fructus Gardeniaes, 20 parts, Radix Glycyrrhizae, 30 parts of Radix Paeoniae Rubra, 30 parts of Cortex Phellodendris.
3. the Chinese medicine oral liquid for the treatment of pig jaundice according to claim 1 and 2, is characterized in that: this Chinese medicine composition is the various conventional extract oral medicine dosage form that contains or do not contain pharmaceutic adjuvant.
4. the Chinese medicine oral liquid for the treatment of pig jaundice according to claim 3, is characterized in that: described preparation can be oral liquid.
5. a method of preparing the Chinese medicine oral liquid for the treatment of pig jaundice as claimed in claim 4, is characterized in that: preparation method is that Chinese medicine powder is broken to certain order number by (1), takes by formula ratio, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, aqueous solution are put into respectively in extraction pot, soaked the regular hour; (3) be heated to uniform temperature, extract certain hour; (4) filter and collect extracting solution; (5) secondary adds a certain amount of water in medicinal residues, continues to extract at a certain temperature certain hour; (6) merge extracted twice liquid, be evaporated at a certain temperature certain volume; (7) fill becomes bottle, gets product.
6. the preparation method of the Chinese medicine oral liquid for the treatment of pig jaundice according to claim 5, is characterized in that: described pulverizing order number is 60-80 order.
7. the preparation method of the Chinese medicine oral liquid for the treatment of pig jaundice according to claim 5, is characterized in that: the extracted twice time is 10-15 hour.
8. the preparation method of the extract oral for the treatment of pig jaundice according to claim 5, is characterized in that: described concentrating under reduced pressure temperature is 30-70 DEG C.
9. the preparation method of the Chinese medicine oral liquid for the treatment of pig jaundice according to claim 5, is characterized in that: described concentrating under reduced pressure volume is original volume 10%-20%.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104800745A (en) * | 2015-05-25 | 2015-07-29 | 袁春梅 | Medicine composition for treating pig yellow fat disease and preparation method of medicine composition |
| CN105641306A (en) * | 2015-10-23 | 2016-06-08 | 吴家峰 | Drug for improving sub-health of sows |
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| CN102846892A (en) * | 2012-08-30 | 2013-01-02 | 喻可安 | Acute icterus type infectious hepatitis treatment decoction |
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| EP0931544A2 (en) * | 1997-12-22 | 1999-07-28 | Kaken Shoyaku Co., Ltd. | NF-kB activity inhibitor |
| CN102846892A (en) * | 2012-08-30 | 2013-01-02 | 喻可安 | Acute icterus type infectious hepatitis treatment decoction |
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| 周正挥等: "《民间兽医特效方剂》", 31 January 2011, 中国农业出版社 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800745A (en) * | 2015-05-25 | 2015-07-29 | 袁春梅 | Medicine composition for treating pig yellow fat disease and preparation method of medicine composition |
| CN105641306A (en) * | 2015-10-23 | 2016-06-08 | 吴家峰 | Drug for improving sub-health of sows |
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Application publication date: 20141210 |