CN108567874A - A kind of tonifying speen and tonifying kidney composition and preparation method thereof - Google Patents

A kind of tonifying speen and tonifying kidney composition and preparation method thereof Download PDF

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CN108567874A
CN108567874A CN201810746076.7A CN201810746076A CN108567874A CN 108567874 A CN108567874 A CN 108567874A CN 201810746076 A CN201810746076 A CN 201810746076A CN 108567874 A CN108567874 A CN 108567874A
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parts
tonifying
speen
tonifying kidney
extracting solution
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阳吉长
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Hunan Orange Technology Co Ltd
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Hunan Orange Technology Co Ltd
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The invention discloses a kind of tonifying speen and tonifying kidney compositions and preparation method thereof, include the following steps:According to each ingredient of parts by weight:Peach kernel, Gorgon fruit, dandelion, cape jasmine, nutmeg, emblic, fingered citron, brush-cherry seed, gingko, Chinese yam, Poria cocos, the fruit of Chinese wolfberry, Radix Glycyrrhizae and pure water extract after decocting, and obtain extracting solution;Step 2:The extracting solution is concentrated into obtain the thick paste that relative density is 1.25~1.30 (60 DEG C);Step 3:Thick paste is dried in vacuo, is got dry extract;Step 4:Maltodextrin is added in the dry cream and dextrin crushes after mixing, 85%~90% ethyl alcohol is then added, then pelletizes, and fluidized drying obtains dry particle.Tonifying speen and tonifying kidney composition in the present invention is powdery granule, and boiling water can be taken after washing open.

Description

A kind of tonifying speen and tonifying kidney composition and preparation method thereof
Technical field
The present invention relates to food processing technology fields more particularly to a kind of tonifying speen and tonifying kidney composition and preparation method thereof.
Background technology
With the reasons such as the increase of people's life stress and bad life habits, eating habit, spleen deficiency kidney deficiency is caused to be drawn Play various illnesss.For male, prostate is that the distinctive sexual glands of male easily cause once spleen kidney goes wrong Prostatitis relevant disease, such as chronic prostatitis, hyperplasia of prostate, hypertrophy of the prostate.
The incidence of chronic prostatitis (ChronicProstatitis, CP) is high, and therapeutic effect is poor, be always puzzlement at One of the important illness of year male, seriously affects routine work and life.According to statistics, the male in China 35 years old or more have 45% with It is upper to suffer from this disease, account for about 40% or more of urological department outpatient clinic patient;There are 2,000,000 patients to go to a doctor every year in the U.S., epidemic disease It is 5%-8.8% to learn investigation.It is estimated that male in life within certain a period of time, has 50% to be perplexed by prostatitis symptom. Due to causing cause of disease complexity, the prostate anatomy of chronic prostatitis special, clinically with complicated symptoms, protracted course is easy Recurrence etc. is characterized, and it is unsatisfactory that modern medicine and pharmacology treats curative effect.
Hyperplasia of prostate is commonly called as hypertrophy of the prostate, and hyperplasia of prostate is one of elderly men common disease, generally after 40 years old , there are related symptoms in the pathological change that hyperplasia takes place after 50 years old.The incidence of hyperplasia of prostate increases with the age and is passed Increase.Hyperplasia of prostate cardinal symptom has dysuria, frequent micturition, urination starting is slow, urine line is powerless, urinates interruption or the sound of rain pattering etc., more The symptoms such as acute urinary retention, urinary retention with overflow incontinence, blood urine notably can also occur.
Currently, for the relevant various diseases of prostate caused by spleen deficiency kidney deficiency, it is good that there is an urgent need to a kind of clinical efficacies, peace Full toxic side effect is small, and patient is easy to the pharmaceutical composition received.
Chinese medicinal formulae is particular about monarch,《Sheng Nong's herbal classic》In just record:" 120 kinds of medicine-feeding is monarch, main to support life; 120 kinds of Chinese medicine is minister, and master nourishs one's nature;Putting in poison 120 kinds makes for assistant, cures mainly disease;Medication must close monarch." " clear Will is clever " paraphrase:120 kinds of top grade is monarch, and main life of supporting is nontoxic with Ying Tian, takes long term usage more and does not hurt sb.'s feelings, is intended to QI invigorating macrobiosis and makes light of one's life by commiting suicide Angle person, this top grade;120 kinds of middle product are minister, and master nourishs one's nature to answer people, toxic, nontoxic, consider it preferably, qi-restoratives to be cured the disease is thin Person, product in leading;Made for assistant with 120 kinds of low-grades, it is mostly malicious to answer ground, can not long term usage, fever and chills perverse trend remove, break accumulation remove it is chronic Disease person, this low-grade.As it can be seen that in the research of Chinese medicine composition, the compatibility combination of each medicinal material is especially particular about, medicine between each medicinal material is passed through The coordinated of effect and pharmacological property, has the function that the toxicity that heightens the effect of a treatment or mitigate.
The present invention combination prior art and application in TCM principle explore a kind of good tonifying speen and tonifying kidney composition.
Invention content
The main object of the present invention is to provide a kind of tonifying speen and tonifying kidney composition, and the composition aims to solve the problem that the chronic forefront of male The problems such as adenositis, hyperplasia of prostate, hypertrophy of the prostate.
To achieve the above object, tonifying speen and tonifying kidney composition proposed by the present invention includes each ingredient of following parts by weight:Peach kernel 1.8~2.5 parts, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, 2.5~4 parts of cape jasmine, 0.8~1.2 part of nutmeg, emblic 1~2 Part, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, 0.8~1.2 part of gingko, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, matrimony vine Sub 4~7 parts, 0.4~0.8 part of Radix Glycyrrhizae, the tonifying speen and tonifying kidney composition are form of powdery particles.
Further, include each ingredient of following parts by weight:2 parts of peach kernel, 4 parts of Gorgon fruit, 3 parts of dandelion, 3 parts of cape jasmine, meat It is 1 part of cardamom, 1.5 parts of emblic, 1.5 parts of fingered citron, 2 parts of brush-cherry seed, 1 part of gingko, 3 parts of Chinese yam, 4 parts of Poria cocos, 5 parts of the fruit of Chinese wolfberry, sweet 0.5 part of grass.
Further, the peach kernel is Dan peach kernels, and the nutmeg is to simmer nutmeg.
Further, the tonifying speen and tonifying kidney composition further includes dextrin and/or maltodextrin.
The present invention also provides a kind of preparation methods of tonifying speen and tonifying kidney composition, include the following steps:
Step 1:According to each ingredient of parts by weight:1.8~2.5 parts of peach kernel, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, Cape jasmine 2.5~4 parts of son, 0.8~1.2 part of nutmeg, 1~2 part of emblic, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, gingko 0.8 ~1.2 parts, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, 0.4~0.8 part of Radix Glycyrrhizae and pure water carry out after decocting Extraction obtains extracting solution;
Step 2:The extracting solution is concentrated into obtain the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:Thick paste is dried in vacuo, is got dry extract;
Step 4:Maltodextrin and dextrin are added in the dry cream to crush after mixing, then it is added 85%~ 90% ethyl alcohol, then pelletizes, and dry dry particle.
Further, the concrete operations of the step 1 are:
It will be according to each ingredient of parts by weight:1.8~2.5 parts of peach kernel, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, cape jasmine 2.5 ~4 parts, 0.8~1.2 part of cardamom, 1~2 part of emblic, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, 0.8~1.2 part of gingko, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, 0.4~0.8 part of Radix Glycyrrhizae and the first parts by weight of purified water decoct laggard Row extracts for the first time and obtains first extract;
First extract is filtered, obtains first extracting solution and filter residue respectively, filter residue is placed in, the second weight is added Part pure water, is extracted and obtains second extract for the second time;
Second extract is filtered, secondary raffinate and filter residue are obtained respectively, by first extracting solution and second extraction Liquid, which merges, obtains the extracting solution.
Further, the concrete operations of the step 2 are:
The extracting solution is concentrated under reduced pressure into obtain the thick paste that relative density is 1.25~1.30 (60 DEG C).
Further, the thickening temperature being concentrated under reduced pressure in the step 2 is 70 DEG C~80 DEG C, and pressure value is -0.06MPa ~-0.08MPa;In the step 3 vacuum drying drying temperature be 65 DEG C~75 DEG C, pressure value be -0.06MPa~- 0.08MPa。
Further, the step 4 specifically includes:According to dry cream:Maltodextrin:Dextrin=4: 2~4: 6~12, in institute State and maltodextrin and dextrin are added in dry cream crush after mixing, be added containing Sucralose, mogroside 85%~ 90% ethyl alcohol, then pelletizes, and fluidized drying obtains dry particle.
Further, first parts by weight of purified water is 7-10 times of each total weight at the mixture being grouped as and measures;Institute It is respectively to be measured at 5-8 times of the total weight for the mixture being grouped as in step 1 to state the second parts by weight of purified water.
Chinese yam tonifying spleen lung kidney qi in tonifying speen and tonifying kidney composition in the present invention, fruit of Chinese wolfberry nourishing kidney yin benefiting essence-blood, the two It shares, reinforcing both QI and YIN, is altogether monarch;Gingko, Gorgon fruit, convergence astringent method, controlling nocturnal emission with astringent drugs are only lost;Nutmeg, fingered citron, Poria cocos, brush-cherry seed, Pu Gong English, drying damp and strengthening spleen, inducing diuresis for treating strangurtia;Peach kernel, emblic, promoting blood circulation and cooling blood are minister above.Jujube tonifying middle-Jiao and Qi, for assistant.Radix Glycyrrhizae tune With all medicines, to make.All medicines share plays tonifying kidney-yin, inducing diuresis for removing edema, the work(of benefiting qi and removing blood stasis altogether.Our tonifying speen and tonifying kidney, inducing diuresis to remove edema, It is promoting blood circulation and removing blood stasis, be suitable for chronic prostatitis, hyperplasia of prostate, hypertrophy of the prostate crowd health care, excellent.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is general The every other embodiment that logical technical staff is obtained without creative efforts belongs to what the present invention protected Range.
In addition, the technical solution between each embodiment of the present invention can be combined with each other, but must be general with this field Logical technical staff can be implemented as basis, will be understood that when the combination of technical solution appearance is conflicting or cannot achieve this The combination of technical solution is not present, also not the present invention claims protection domain within.
The present invention proposes a kind of tonifying speen and tonifying kidney composition, which includes each ingredient of following parts by weight: 1.8~2.5 parts of peach kernel, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, 2.5~4 parts of cape jasmine, 0.8~1.2 part of nutmeg, emblic 1~2 part, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, 0.8~1.2 part of gingko, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, 0.4~0.8 part of Radix Glycyrrhizae, the tonifying speen and tonifying kidney composition are form of powdery particles.
From the angle of traditional Chinese medicine just solved, the Chinese yam tonifying spleen lung kidney qi in tonifying speen and tonifying kidney composition provided by the invention, Chinese holly Matrimony vine nourishing kidney yin benefiting essence-blood, Papillary, reinforcing both QI and YIN are altogether monarch;Gingko, Gorgon fruit, convergence astringent method, controlling nocturnal emission with astringent drugs are only lost;Pork and beans Cool, fingered citron, Poria cocos, brush-cherry seed, dandelion, drying damp and strengthening spleen, inducing diuresis for treating strangurtia;Peach kernel, emblic, promoting blood circulation and cooling blood are minister above. Jujube tonifying middle-Jiao and Qi, for assistant.Radix Glycyrrhizae coordinating the drug actions of a prescription, to make.All medicines share, plays tonifying kidney-yin altogether, inducing diuresis for removing edema, benefiting qi and removing blood stasis it Work(.It is our tonifying speen and tonifying kidney, inducing diuresis to remove edema, promoting blood circulation and removing blood stasis, it is suitable for chronic prostatitis, hyperplasia of prostate, hypertrophy of the prostate people The health care of group, excellent.
It should be noted that the peach kernel is Dan peach kernels;Specifically, can be that peach kernel is placed in boiling water, heating boil to Kind micro- swell of skin is pulled out, slightly steeps, picks up in cold water, kind of skin and benevolence is rubbed open, dry, and kind of skin of winnowing with a dustpan removes up to Dan peach kernels It has gone to non-medicinal part, active principle to be easy to fried, has improved drug effect.In addition, the nutmeg can be to simmer nutmeg.
Further, the tonifying speen and tonifying kidney composition further includes dextrin and/or maltodextrin, to improve composition grain Viscosity, make it have certain viscosity and be readily soluble in water again.
Further, the preparation method of tonifying speen and tonifying kidney composition proposed by the present invention includes the following steps:
Step 1:According to each ingredient of parts by weight:1.8~2.5 parts of peach kernel, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, Cape jasmine 2.5~4 parts of son, 0.8~1.2 part of nutmeg, 1~2 part of emblic, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, gingko 0.8 ~1.2 parts, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, 0.4~0.8 part of Radix Glycyrrhizae and pure water carry out after decocting Extraction obtains extracting solution;
Step 2:The extracting solution is concentrated into obtain the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:Thick paste is dried in vacuo, is got dry extract;
Step 4:Maltodextrin and dextrin are added in the dry cream to crush after mixing, then it is added 85%~ 90% ethyl alcohol, then pelletizes, and fluidized drying obtains dry particle.
It is understood that can also include the technologies of the package such as whole grain sieving, Nei Bao and outsourcing after the step 4.
Tonifying speen and tonifying kidney composition proposed by the present invention and preparation method thereof is carried out specifically below by way of specific embodiment It is bright:
Embodiment one
A kind of tonifying speen and tonifying kidney composition includes each ingredient of following parts by weight:2 parts of peach kernel, 4 parts of Gorgon fruit, 3 parts of dandelion, 3 parts of cape jasmine, 1 part of nutmeg, 1.5 parts of emblic, 1.5 parts of fingered citron, 2 parts of brush-cherry seed, 1 part of gingko, 3 parts of Chinese yam, 4 parts of Poria cocos, Chinese holly 5 parts of matrimony vine, 0.5 part of Radix Glycyrrhizae.
The preparation method of the tonifying speen and tonifying kidney composition includes the following steps:
Step 1:Above-mentioned each ingredient is weighed respectively:Peach kernel 100g, Gorgon fruit 200g, dandelion 150g, cape jasmine 150g, Pork and beans Cool 50g, emblic 75g, fingered citron 75g, brush-cherry seed 100g, gingko 50g, Chinese yam 150g, Poria cocos 200g, fruit of Chinese wolfberry 250g, Radix Glycyrrhizae The mixture of 25g, said mixture is placed in extractor, and the pure water of 8 times of amount parts of said mixture total weight is added, and setting carries It is 100 DEG C to take temperature, is extracted 120 minutes, carries out 350 mesh filter screen filterings, obtains first extracting solution and filter residue respectively, filter residue is set In extractor, and the pure water of 6 times of amount parts of total weight of the mixture in step 1 is added, setting Extracting temperature is 100 degree, extraction 60 Minute, 350 mesh filter screen filterings are carried out, secondary raffinate and filter residue is obtained respectively, first extracting solution is merged with secondary raffinate Obtain extracting solution;
Step 2:(temperature is concentrated under reduced pressure in gained extracting solution:70~80 DEG C, vacuum degree:- 0.06~-0.08Mpa) to To the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:(temperature is dried in vacuo to thick paste:65~75 DEG C, vacuum degree:- 0.06~-0.08Mpa), it obtains dry Cream about 260g;
Step 4:Using granulation, drying, whole grain, particle yield as inspection target, determine that the dry cream auxiliary material ratio of this product is dry Cream:Maltodextrin:Dextrin=4: 3: 9;Dextrin about 570g is added, maltodextrin about 190g is ground into fine powder (80 mesh);It adds It dissolved with 0.6g Sucraloses, 85%~90% ethanol solution of 0.4g mogrosides, then pelletizes, and dry to containing Water is less than 4%, and 16 mesh sieves obtain dry particle 1000g.
Embodiment two
A kind of tonifying speen and tonifying kidney composition includes each ingredient of following parts by weight:1.8 parts of peach kernel, 3 parts of Gorgon fruit, dandelion 2.5 Part, 2.5 parts of cape jasmine, 0.8 part of nutmeg, 1 part of emblic, 2 parts of fingered citron, 2.5 parts of brush-cherry seed, 1.2 parts of gingko, 3.5 parts of Chinese yam, Fu 6 parts of Siberian cocklebur, 7 parts of the fruit of Chinese wolfberry, 0.8 part of Radix Glycyrrhizae.
The preparation method of the tonifying speen and tonifying kidney composition includes the following steps:
Step 1:Above-mentioned each ingredient is weighed respectively:1.8 parts of peach kernel, 3 parts of Gorgon fruit, 2.5 parts of dandelion, 2.5 parts of cape jasmine, meat 0.8 part of cardamom, 1 part of emblic, 2 parts of fingered citron, 2.5 parts of brush-cherry seed, 1.2 parts of gingko, 3.5 parts of Chinese yam, 6 parts of Poria cocos, the fruit of Chinese wolfberry 7 Part, the mixture of 0.8 part of Radix Glycyrrhizae, said mixture is placed in extractor, the pure of 8 times of amount parts of said mixture total weight is added Water, setting Extracting temperature are 100 DEG C, extract 120 minutes, carry out 350 mesh filter screen filterings, obtain first extracting solution and filter respectively Filter residue is placed in extractor by slag, and the pure water of 6 times of amount parts of total weight of the mixture in step 1 is added, and setting Extracting temperature is It 100 degree, extracts 60 minutes, carries out 350 mesh filter screen filterings, secondary raffinate and filter residue are obtained respectively, by first extracting solution and two Secondary extracting solution, which merges, obtains extracting solution;
Step 2:(temperature is concentrated under reduced pressure in gained extracting solution:70~80 DEG C, vacuum degree:- 0.06~-0.08Mpa) to To the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:(temperature is dried in vacuo to thick paste:65~75 DEG C, vacuum degree:- 0.06~-0.08Mpa), it obtains dry Cream;
Step 4:Using granulation, drying, whole grain, particle yield as inspection target, determine that the dry cream auxiliary material ratio of this product is dry Cream:Maltodextrin:Dextrin=4: 2: 12;It is proportionally added into dextrin, maltodextrin and is ground into fine powder (80 mesh);Add dissolved with 85%~90% ethanol solution of Sucralose, mogroside, then pelletizes, and drying to water content is less than 4%, 16 mesh sieves, obtain dry particle.
Embodiment three
A kind of tonifying speen and tonifying kidney composition includes each ingredient of following parts by weight:2.5 parts of peach kernel, 5 parts of Gorgon fruit, dandelion 4 Part, 4 parts of cape jasmine, 1.2 parts of nutmeg, 2 parts of emblic, 1 part of fingered citron, 1.8 parts of brush-cherry seed, 0.8 part of gingko, 2.5 parts of Chinese yam, Poria cocos 3 parts, 4 parts of the fruit of Chinese wolfberry, 0.4 part of Radix Glycyrrhizae.
The preparation method of the tonifying speen and tonifying kidney composition includes the following steps:
Step 1:Above-mentioned each ingredient is weighed respectively:2.5 parts of peach kernel, 5 parts of Gorgon fruit, 4 parts of dandelion, 4 parts of cape jasmine, nutmeg 1.2 parts, it is 2 parts of emblic, 1 part of fingered citron, 1.8 parts of brush-cherry seed, 0.8 part of gingko, 2.5 parts of Chinese yam, 3 parts of Poria cocos, 4 parts of the fruit of Chinese wolfberry, sweet The mixture of 0.4 part of grass, said mixture is placed in extractor, and the pure water of 8 times of amount parts of said mixture total weight is added, if It is 100 DEG C to set Extracting temperature, is extracted 120 minutes, carries out 350 mesh filter screen filterings, obtains first extracting solution and filter residue respectively, will filter Slag is placed in extractor, and the pure water of 6 times of amount parts of total weight of the mixture in step 1 is added, and setting Extracting temperature is 100 degree, is carried It takes 60 minutes, carries out 350 mesh filter screen filterings, secondary raffinate and filter residue are obtained respectively, by first extracting solution and secondary raffinate Merge and obtains extracting solution;
Step 2:(temperature is concentrated under reduced pressure in gained extracting solution:70~80 DEG C, vacuum degree:- 0.06~-0.08Mpa) to To the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:(temperature is dried in vacuo to thick paste:65~75 DEG C, vacuum degree:- 0.06~-0.08Mpa), it obtains dry Cream;
Step 4:Using granulation, drying, whole grain, particle yield as inspection target, determine that the dry cream auxiliary material ratio of this product is dry Cream:Maltodextrin:Dextrin=4: 4: 6;It is proportionally added into dextrin, maltodextrin and is ground into fine powder (80 mesh);Add dissolved with 85%~90% ethanol solution of Sucralose, mogroside, then pelletizes, and fluidized drying to water content is less than 4%, 16 mesh sieves obtain dry particle.
Example IV
A kind of tonifying speen and tonifying kidney composition includes each ingredient of following parts by weight:1.8 parts of Dan peach kernels, 4 parts of Gorgon fruit, dandelion 4 Part, simmers 1 part of nutmeg, 2 parts of emblic, 1 part of fingered citron, 2 parts of brush-cherry seed, 1.2 parts of gingko, 3 parts of Chinese yam, Poria cocos 3 at 2.5 parts of cape jasmine Part, 5 parts of the fruit of Chinese wolfberry, 0.4 part of Radix Glycyrrhizae.
The preparation method of the tonifying speen and tonifying kidney composition includes the following steps:
Step 1:Above-mentioned each ingredient is weighed respectively:1.8 portions of Dan peach kernels, 4 parts of dandelion, 2.5 parts of cape jasmine, are simmered 4 parts of Gorgon fruit It is 1 part of nutmeg, 2 parts of emblic, 1 part of fingered citron, 2 parts of brush-cherry seed, 1.2 parts of gingko, 3 parts of Chinese yam, 3 parts of Poria cocos, 5 parts of the fruit of Chinese wolfberry, sweet The mixture of 0.4 part of grass, said mixture is placed in extractor, and the pure water of 8 times of amount parts of said mixture total weight is added, if It is 100 DEG C to set Extracting temperature, is extracted 120 minutes, carries out 350 mesh filter screen filterings, obtains first extracting solution and filter residue respectively, will filter Slag is placed in extractor, and the pure water of 6 times of amount parts of total weight of the mixture in step 1 is added, and setting Extracting temperature is 100 degree, is carried It takes 60 minutes, carries out 350 mesh filter screen filterings, secondary raffinate and filter residue are obtained respectively, by first extracting solution and secondary raffinate Merge and obtains extracting solution;
Step 2:(temperature is concentrated under reduced pressure in gained extracting solution:70~80 DEG C, vacuum degree:- 0.06~-0.08Mpa) to To the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:(temperature is dried in vacuo to thick paste:65~75 DEG C, vacuum degree:- 0.06~-0.08Mpa), it obtains dry Cream;
Step 4:Using granulation, drying, whole grain, particle yield as inspection target, determine that the dry cream auxiliary material ratio of this product is dry Cream:Maltodextrin:Dextrin=4: 3: 9;It is proportionally added into dextrin, maltodextrin and is ground into fine powder (80 mesh);Add dissolved with 85%~90% ethanol solution of Sucralose, mogroside, then pelletizes, and fluidized drying to water content is less than 4%, 16 mesh sieves obtain dry particle.
Embodiment five
A kind of tonifying speen and tonifying kidney composition includes each ingredient of following parts by weight:2 parts of Dan peach kernels, 4 parts of Gorgon fruit, dandelion 3 Part, simmers 1 part of nutmeg, 1.5 parts of emblic, 1.5 parts of fingered citron, 2 parts of brush-cherry seed, 1 part of gingko, 3 parts of Chinese yam, Poria cocos 4 at 3 parts of cape jasmine Part, 5 parts of the fruit of Chinese wolfberry, 0.5 part of Radix Glycyrrhizae.
The preparation method of the tonifying speen and tonifying kidney composition includes the following steps:
Step 1:Above-mentioned each ingredient is weighed respectively:2 portions of Dan peach kernels, 3 parts of dandelion, 3 parts of cape jasmine, simmer Pork and beans at 4 parts of Gorgon fruit Cool 1 part, 1.5 parts of emblic, 1.5 parts of fingered citron, 2 parts of brush-cherry seed, 1 part of gingko, 3 parts of Chinese yam, 4 parts of Poria cocos, 5 parts of the fruit of Chinese wolfberry, Radix Glycyrrhizae 0.5 part of mixture, said mixture is placed in extractor, and the pure water of 8 times of amount parts of said mixture total weight, setting is added Extracting temperature is 100 DEG C, is extracted 120 minutes, carries out 350 mesh filter screen filterings, first extracting solution and filter residue is obtained respectively, by filter residue It is placed in extractor, and the pure water of 6 times of amount parts of total weight of the mixture in step 1 is added, setting Extracting temperature is 100 degree, extraction 60 minutes, 350 mesh filter screen filterings are carried out, obtain secondary raffinate and filter residue respectively, first extracting solution and secondary raffinate are closed And obtain extracting solution;
Step 2:(temperature is concentrated under reduced pressure in gained extracting solution:70~80 DEG C, vacuum degree:- 0.06~-0.08Mpa) to To the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:(temperature is dried in vacuo to thick paste:65~75 DEG C, vacuum degree:- 0.06~-0.08Mpa), it obtains dry Cream;
Step 4:Using granulation, drying, whole grain, particle yield as inspection target, determine that the dry cream auxiliary material ratio of this product is dry Cream:Maltodextrin:Dextrin=4: 3: 12;It is proportionally added into dextrin, maltodextrin and is ground into fine powder (80 mesh);Add dissolved with 85%~90% ethanol solution of Sucralose, mogroside, then pelletizes, and fluidized drying to water content is less than 4%, 16 mesh sieves obtain dry particle.
Model case/clinical test results:
Clinical test is carried out to tonifying speen and tonifying kidney composition below:There are prostatic disorders in the selection stage at 35~55 years old age Male 180, cardinal symptom shows as shiver with cold, fever, fatigue and weak and paruria etc..It is randomly divided into 6 groups, every group 30 People, the first 5 groups tonifying speen and tonifying kidney composition electuaries taken respectively in Examples 1 to 5, the 6th group is taken equivalent blank placebo.Wherein Tonifying speen and tonifying kidney composition in Examples 1 to 5 is that one dosage is 2 bags, every bag of 10g, is respectively taken on an empty stomach within 1 hour before meals sooner or later 1 bag.The symptomatic condition of user is investigated after taking one month, result is investigated and please refers to table 1.
The symptom of 1 user of table, which improves, investigates result
Experimental group 1 2 3 4 5 6
Shiver with cold improves 27 24 25 27 27 1
Fever improves 26 25 25 26 28 1
Fatigue and weak improves 26 24 24 25 27 1
Paruria improves 26 25 24 25 27 0
Typical treatment case:
Patient one, man, 35 years old, and Symptoms are frequent micturition, urgent urination, and odynuria, tcm diagnosis is siltation internal resistance, spleen kidney is double empty. The tonifying speen and tonifying kidney solid beverage that the embodiment of the present invention 1 is prepared now is taken, twice a day, a 10g takes for one hour before meals With improving after taking three months, continue above symptom after taking three months and disappear.
Patient two, man, 45 years old, and Symptoms are shiver with cold, fever, frequent micturition, odynuria, and tcm diagnosis is siltation internal resistance, spleen kidney Double void.The tonifying speen and tonifying kidney solid beverage that the embodiment of the present invention 2 is prepared now is taken, twice a day, a 10g, one is small before meals When take, take with obvious effects after half a year, continue the above symptom after taking half a year and disappear.
Patient three, man, 42 years old, Symptoms dizziness and tinnitus, malaise, urethra scorching hot, tcm diagnosis be damp-heat accumulation, Spleen kidney is double empty.The tonifying speen and tonifying kidney solid beverage that the embodiment of the present invention 3 is prepared is taken, twice a day, a 10g, before meals one Hour takes, and improves after taking three months, continues the above symptom after taking three months and disappears.
Patient four, man, 48 years old, and Symptoms are frequent micturition, the urinary incontinence, and chronic prostate is once diagnosed as in local hospital Inflammation, prostate bilateral are increased, and through injection of antibiotic, the treatments such as massage of prostate make moderate progress, but Relapse rate, nearly 2 Occasionally there is blood urine in the moon.Tcm diagnosis is damp-heat accumulation, the double void of spleen kidney.It is solid to take the tonifying speen and tonifying kidney that the embodiment of the present invention 4 is prepared Body beverage, twice a day, a 10g are taken for one hour before meals, and symptom improves after taking half a year, continues to take more than after half a year Symptom disappears.
Patient five, man, 52 years old, and dysuria, urine line are powerless, and lateral lobe of prostate gland expands, and intermediate sulcus disappears, and tcm diagnosis is Damp-heat accumulation, spleen kidney are double empty.The tonifying speen and tonifying kidney solid beverage that the embodiment of the present invention 5 is prepared is taken, twice a day, once 10g takes for one hour before meals, and symptom improves after taking half a year, continues after taking half a year, and dysuria disappears with urine line inability symptom It loses;Prostate volume is reduced into 64% before taking.
Table 2 is please referred to, table 2 is that the prostate after taking the solid beverage of tonifying speen and tonifying kidney composition composition of the present invention is routinely examined Survey table.
The prostate conventional detection table of 2 user of table
The solid beverage that the tonifying speen and tonifying kidney composition that can be observed to prepare in the present embodiment by table 2 forms, the urination of patient Exception is obviously improved, and prostate volume hyperplasia is significantly improved.
The above case shows that tonifying speen and tonifying kidney solid beverage provided by the invention has tonifying speen and tonifying kidney, inducing diuresis to remove edema, promoting blood circulationization Stasis of blood and other effects, for health care's excellent of chronic prostatitis, hyperplasia of prostate, hypertrophy of the prostate crowd etc..Simultaneously Tonifying speen and tonifying kidney solid beverage clinic provided by the invention does not find that adverse reaction, drug safety are reliable.
In the description of this specification, reference term " embodiment ", " another embodiment ", " other embodiment " or " The description of one embodiment~X embodiment " etc. mean specific features described in conjunction with this embodiment or example, structure, material or Person's feature is included at least one embodiment or example of the invention.In the present specification, to the schematic table of above-mentioned term It states and may not refer to the same embodiment or example.Moreover, specific features, structure, material, method and step or the spy of description Point can be combined in any suitable manner in any one or more of the embodiments or examples.
It should be noted that herein, the terms "include", "comprise" or its any other variant are intended to non-row His property includes, so that process, method, article or device including a series of elements include not only those elements, and And further include other elements that are not explicitly listed, or further include for this process, method, article or device institute it is intrinsic Element.In the absence of more restrictions, the element limited by sentence "including a ...", it is not excluded that including this There is also other identical elements in the process of element, method, article or device.
The embodiments of the present invention are for illustration only, can not represent the quality of embodiment.
The above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although with reference to preferred embodiment to this hair It is bright to be described in detail, it will be understood by those of ordinary skill in the art that, it can modify to technical scheme of the present invention Or equivalent replacement should all cover the claim in the present invention without departing from the objective and range of technical solution of the present invention In range.

Claims (10)

1. a kind of tonifying speen and tonifying kidney composition, which is characterized in that each ingredient including following parts by weight:1.8~2.5 parts of peach kernel, Gorgon euryale 3~5 parts real, 2.5~4 parts of dandelion, 2.5~4 parts of cape jasmine, 0.8~1.2 part of nutmeg, 1~2 part of emblic, fingered citron 1~2 It is part, 1.8~2.5 parts of brush-cherry seed, 0.8~1.2 part of gingko, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, sweet 0.4~0.8 part of grass, the tonifying speen and tonifying kidney composition are form of powdery particles.
2. tonifying speen and tonifying kidney composition as described in claim 1, which is characterized in that each ingredient including following parts by weight:Peach kernel 2 Part, 4 parts of Gorgon fruit, 3 parts of dandelion, 3 parts of cape jasmine, 1 part of nutmeg, 1.5 parts of emblic, 1.5 parts of fingered citron, 2 parts of brush-cherry seed, gingko 1 Part, 3 parts of Chinese yam, 4 parts of Poria cocos, 5 parts of the fruit of Chinese wolfberry, 0.5 part of Radix Glycyrrhizae.
3. tonifying speen and tonifying kidney composition as claimed in claim 1 or 2, which is characterized in that the peach kernel is Dan peach kernels, the Pork and beans Cool is to simmer nutmeg.
4. tonifying speen and tonifying kidney composition as claimed in claim 1 or 2, which is characterized in that the tonifying speen and tonifying kidney composition further includes Dextrin and/or maltodextrin.
5. a kind of preparation method of tonifying speen and tonifying kidney composition, which is characterized in that include the following steps:
Step 1:According to each ingredient of parts by weight:1.8~2.5 parts of peach kernel, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, cape jasmine 2.5~4 parts, 0.8~1.2 part of nutmeg, 1~2 part of emblic, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, gingko 0.8~ 1.2 parts, 2.5~3.5 parts of Chinese yam, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, 0.4~0.8 part of Radix Glycyrrhizae and pure water are carried after decocting It takes, obtains extracting solution;
Step 2:The extracting solution is concentrated into obtain the thick paste that relative density is 1.25~1.30 (60 DEG C);
Step 3:Thick paste is dried in vacuo, is got dry extract;
Step 4:Maltodextrin is added in the dry cream and dextrin crushes after mixing, 85%~90% second is then added Then alcohol is pelletized, and dry dry particle.
6. the preparation method of tonifying speen and tonifying kidney composition as claimed in claim 5, which is characterized in that the specific behaviour of the step 1 As:
It will be according to each ingredient of parts by weight:1.8~2.5 parts of peach kernel, 3~5 parts of Gorgon fruit, 2.5~4 parts of dandelion, cape jasmine 2.5~4 Part, 0.8~1.2 part of cardamom, 1~2 part of emblic, 1~2 part of fingered citron, 1.8~2.5 parts of brush-cherry seed, 0.8~1.2 part of gingko, mountain 2.5~3.5 parts of medicine, 3~6 parts of Poria cocos, 4~7 parts of the fruit of Chinese wolfberry, 0.4~0.8 part of Radix Glycyrrhizae and the first parts by weight of purified water carry out after decocting It extracts for the first time and obtains first extract;
First extract is filtered, obtains first extracting solution and filter residue respectively, it is pure that filter residue is placed in the second parts by weight of addition Water is extracted and obtains second extract for the second time;
Second extract is filtered, obtains secondary raffinate and filter residue respectively, first extracting solution and secondary raffinate are closed And obtain the extracting solution.
7. the preparation method of tonifying speen and tonifying kidney composition as claimed in claim 5, which is characterized in that the specific behaviour of the step 2 As:
The extracting solution is concentrated under reduced pressure into obtain the thick paste that relative density is 1.25~1.30 (60 DEG C).
8. the preparation method of tonifying speen and tonifying kidney composition as claimed in claim 7, which is characterized in that depressurized in the step 2 dense The thickening temperature of contracting is 70 DEG C~80 DEG C, and pressure value is -0.06MPa~-0.08MPa;It is vacuum drying dry in the step 3 Dry temperature is 65 DEG C~75 DEG C, and pressure value is -0.06MPa~-0.08MPa.
9. the preparation method of tonifying speen and tonifying kidney composition as claimed in claim 5, which is characterized in that the step 4 is specifically wrapped It includes:According to dry cream:Maltodextrin:Dextrin=4: 2~4: 6~12, maltodextrin is added in the dry cream and dextrin mixing is equal It is crushed after even, 85%~90% ethyl alcohol containing Sucralose, mogroside is added, then pelletizes, and fluidized drying Obtain dry particle.
10. the preparation method of tonifying speen and tonifying kidney composition as claimed in claim 6, which is characterized in that first parts by weight are pure Water is that 7-10 times of each total weight at the mixture being grouped as is measured;Second parts by weight of purified water is in step 1 respectively at grouping At 5-8 times of total weight of mixture measure.
CN201810746076.7A 2018-07-09 2018-07-09 A kind of tonifying speen and tonifying kidney composition and preparation method thereof Pending CN108567874A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435712A (en) * 2014-12-01 2015-03-25 肖中喜 Drink granules for treating prostatic diseases
CN106955348A (en) * 2017-05-19 2017-07-18 魏增强 Chinese medicine composition and preparation method for treating chronic nephritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435712A (en) * 2014-12-01 2015-03-25 肖中喜 Drink granules for treating prostatic diseases
CN106955348A (en) * 2017-05-19 2017-07-18 魏增强 Chinese medicine composition and preparation method for treating chronic nephritis

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