CN108553368A - A kind of snake gourd fruit pulp skin whitener and its preparation process - Google Patents
A kind of snake gourd fruit pulp skin whitener and its preparation process Download PDFInfo
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- CN108553368A CN108553368A CN201810599368.2A CN201810599368A CN108553368A CN 108553368 A CN108553368 A CN 108553368A CN 201810599368 A CN201810599368 A CN 201810599368A CN 108553368 A CN108553368 A CN 108553368A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The invention discloses a kind of snake gourd fruit pulp skin whitener and its preparation processes.By oil phase raw material：Stearic acid 15%, hexadecanol 2%, isopropyl palmitate 4%, lanolin 2%, methyl hydroxybenzoate 0.1% are in 80 DEG C of emulsified 45min, Aqueous Phase Raw Material：Triethanolamine 1.9%, glycerine 8%, azone 1%, water 65%, snakegourd fruit flesh extract 1% are in 90 DEG C of emulsified 45min, after the two is homogeneous, Aqueous Phase Raw Material is added in four-necked bottle, magnetic stirring apparatus is started, control rotating speed is 3000r/min, is slowly added into oil phase raw material, stir 15min, stop heating, essence is added when temperature is down to 40 to 45 DEG C, is sufficiently stirred to obtain snake gourd fruit pulp skin whitener.It can not only keep the balance of moisture of skin, and can also supplement important oil components, hydrophily moisturizing ingredient and moisture, and can be allowed to be absorbed by skin, achieve the purpose that conditioning and skin nutrition as the carrier of active constituent and medicament.
Description
Technical field
The present invention relates to cosmetic field more particularly to a kind of snake gourd fruit pulp skin whitener and its preparation processes.
Background technology
Creams class cosmetics are to keep making for the purpose of appropriate moisture in the outmost cuticula of skin, especially skin
Cosmetics.Its feature is can not only to keep the balance of moisture of skin, and can also supplement important oil components, hydrophilic
Property moisturizing ingredient and moisture, and can be allowed to be absorbed by skin as the carrier of active constituent and medicament, reach conditioning and nutrition
The purpose of skin.Product use scope is extensive, has preferable application prospect.
Snakegourd fruit flesh is usually used in cosmetic formulations in ancient times, has moist whitening effect, by upper section the study found that Chinese juniper
Building fruit flesh water extract has apparent tyrosinase inhibitory action, and tyrosinase inhibitory action is than Chinese medicines such as the root of Dahurain angelica, Radix Angelicae Sinensis
Effect is preferable.
Invention content
The purpose of the present invention is to provide a kind of snake gourd fruit pulp skin whitener and its preparation processes, and preparing skin whitener has conditioning
With skin nutrition effect.
The present invention uses following technical scheme to achieve the above object：
A kind of snake gourd fruit pulp skin whitener, including the raw material of following weight ratio are prepared, oil phase raw material：Stearic acid 15%,
Hexadecanol 2%, isopropyl palmitate 4%, lanolin 2%, methyl hydroxybenzoate 0.1%；Aqueous Phase Raw Material：It is triethanolamine 1.9%, sweet
Oil 8%, azone 1%, water 65%, snakegourd fruit flesh extract 1%.
A kind of preparation process of snake gourd fruit pulp skin whitener, by oil phase raw material：Stearic acid 15%, hexadecanol 2%, palmitic acid isopropyl
Ester 4%, lanolin 2%, methyl hydroxybenzoate 0.1% are in 80 DEG C of emulsified 45min, Aqueous Phase Raw Material：Triethanolamine 1.9%, glycerine
8%, azone 1%, water 65%, snakegourd fruit flesh extract 1% are in 90 DEG C of emulsified 45min, after the two is homogeneous, by Aqueous Phase Raw Material
It being added in four-necked bottle, starts magnetic stirring apparatus, control rotating speed is 3000r/min, is slowly added into oil phase raw material, stirs 15min,
Stop heating, essence is added when temperature is down to 40 to 45 DEG C, is sufficiently stirred to obtain snake gourd fruit pulp skin whitener.
The preparation method of snakegourd fruit flesh extract, includes the following steps：Snakegourd fruit flesh 70g is taken, adds 10 times of amount water, impregnates
30min is heated to reflux 1h at 95 DEG C, filtering, and the dregs of a decoction and filter paper add 10 times of amount water to repeat extraction 2 times, filtering, and filtrate merges,
It concentrates and is settled in 100mL volumetric flasks and preserve, obtain snakegourd fruit flesh extract.
The beneficial effects of the invention are as follows：The constant incubator in (40 ± 1) DEG C of snake gourd fruit pulp skin whitener prepared by the present invention
After middle holding for 24 hours, without water-oil separating phenomenon after restoring to room temperature, meets and advised under the resistance to hot-activity of QB/T18572004 moisturizing creams
It is fixed；After being kept for 24 hours at -5 DEG C~-10 DEG C, without water-oil separating phenomenon after restoring to room temperature, meet QB/T18572004 moisturizing creams
Cold-resistant item under provide；PH value is 7.44 ± 0.05, meets the pH items lower 4.0~8.5 of QB/T18572004 moisturizing creams
Regulation.It can not only keep the balance of moisture of skin, and can also supplement important oil components, hydrophily moisturizing ingredient and
Moisture, and can be allowed to be absorbed by skin, achieve the purpose that conditioning and skin nutrition as the carrier of active constituent and medicament.
Specific implementation mode
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment
Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
The every other embodiment that art personnel are obtained without making creative work belongs to the model that the present invention protects
It encloses.
A kind of preparation process of snake gourd fruit pulp skin whitener, by oil phase raw material：Stearic acid 15%, hexadecanol 2%, palmitic acid isopropyl
Ester 4%, lanolin 2%, methyl hydroxybenzoate 0.1% are in 80 DEG C of emulsified 45min, Aqueous Phase Raw Material：Triethanolamine 1.9%, glycerine
8%, azone 1%, water 65%, snakegourd fruit flesh extract 1% are in 90 DEG C of emulsified 45min, after the two is homogeneous, by Aqueous Phase Raw Material
It being added in four-necked bottle, starts magnetic stirring apparatus, control rotating speed is 3000r/min, is slowly added into oil phase raw material, stirs 15min,
Stop heating, essence is added when temperature is down to 40 to 45 DEG C, is sufficiently stirred to obtain snake gourd fruit pulp skin whitener.
The wherein preparation method of snakegourd fruit flesh extract, includes the following steps：Snakegourd fruit flesh 70g is taken, 10 times of amount water, leaching are added
30min is steeped, 1h is heated to reflux at 95 DEG C, is filtered, the dregs of a decoction and filter paper add 10 times of amount water to repeat extraction 2 times, filtering, and filtrate is closed
And concentrate and be settled in 100mL volumetric flasks and preserve, obtain snakegourd fruit flesh extract.
Pass through the optimization of experimental technique condition
(1) emulsification times optimize
The emulsification times of oil phase are investigated, 15min, 30min, the 45min and 60min4 different times of experiment selection；It is right
The emulsification times of water phase are investigated, 15min, 30min, the 45min and 60min4 different times of experiment selection；The emulsification of two-phase tries
It tests 5min, 10min, the 15min and 20min4 different times of selection to be investigated, high speed centrifugation after skin whitener is made, observes
Delamination.
(2) optimization of rotating speed
Experiment selection 800r/min, 1500r/min, 2000r/min, 3000r/min, 4 different rotating speeds carry out two-phase
High speed centrifugation after skin whitener is made in emulsification, observes delamination.
(3) optimization of emulsifying temperature
Experiment has selected 60 DEG C, 70 DEG C, 80 DEG C, 90 DEG C to be investigated respectively to the emulsifying temperature of water phase and oil phase, makes
At high speed centrifugation after skin whitener, delamination is observed.
As a result with analysis
The determination of 3.1 emulsification times
The emulsification times of table 3-7 oil phases are investigated
The investigation of table 3-8 water phase emulsification times
The investigation of table 3-9 biphase emulsification times
As seen from the above table, emulsification times influence test result more apparent, and oil phase emulsification times have layering in 15min,
In 30min, effect is general, and in 45min and 60min, effect is preferable；Water phase emulsification times have layering in 15min,
Effect is general when 30min, and in 45min and 60min, effect is preferable；Emulsifying effectiveness of the biphase emulsification time in 5min is poor,
There is layering in 10min, effect when 15min and 20min is preferable.Therefore, consider from experimentation cost and on the time, determine oil phase
Emulsification times are 45min, and water phase emulsification times are 45min, and the biphase emulsification time is 15min.
The determination of 3.2 emulsifying rates
The determination of table 3-10 emulsifying rates
As seen from the above table, during making snake gourd fruit pulp skin whitener, emulsifying rate when biphase emulsification is 3000r/min
When emulsifying effectiveness it is best, effect when 2000r/min is taken second place, and effect is worst when 800r/min.Therefore, experiment selection 3000r/
Min is biphase emulsification speed.
The determination of 3.3 emulsifying temperatures
The determination of table 3-11 emulsifying temperatures
It can be seen from the above result that the effect when emulsifying temperature of oil phase is 60 DEG C is poor, effect at 70 DEG C is general, 80 DEG C
Emulsifying effectiveness when with 90 DEG C is preferable.Therefore, experiment selects 80 DEG C of optimum temperatures emulsified as oil phase.
Therefore, determine that the optimised process of snake gourd fruit pulp skin whitener is by testing above：Oil phase in 80 DEG C of emulsified 45min,
Water phase is added in four-necked bottle in 90 DEG C of emulsified 45min after the two is homogeneous by water phase, starts magnetic stirring apparatus, and control turns
Speed is 3000r/min, is slowly added into oil phase, stirs 15min, stops heating, essence is added when temperature is down to 40 to 45 DEG C, fills
Divide and stirs to obtain snake gourd fruit pulp skin whitener.
The quality testing of skin whitener；
The ingredient of cosmetics is varied, considerably complicated, China《Cosmetics health specification》Define more than 700 kind disabling objects
Matter, safety, stability and validity by detecting skin care item can effectively evaluate the quality of skin care item.This experimental evidence
《People's Republic of China's light industry standard》Detection method under middle moisturizing cream item has carried out quality testing to this product.
Test material and method
1.1 materials and instrument
Snake gourd fruit pulp skin whitener sample, FA1104 types electronic balance (Shanghai balance equipment factory), pH meter, constant incubator are general
Logical refrigerator.
1.2 organoleptic indicators detect
It takes this product to carry out visual observations under room temperature and non-direct sunlight in right amount, evaluates its appearance, color；It is another to take this product suitable
Amount is differentiated with smell and evaluates its fragrance；The appropriate arm surface for being uniformly applied to cleaning is taken, its coating sense is evaluated.As a result
Using QB/T18572004 as evaluation criterion.
1.3 physical and chemical indexes detect
1.3.1 heat-resisting
Constant incubator is adjusted in advance and arrives (40 ± 1) DEG C, this product is taken in closed container, to be placed in constant incubator in right amount
It is interior, it takes out, restores to visual observations after room temperature afterwards for 24 hours.
1.3.2 cold-resistant
Refrigerator is adjusted in advance and arrives -5 DEG C~-10 DEG C, this product is taken in closed container, to be placed in refrigerator, take afterwards for 24 hours in right amount
Go out, restores to visual observations after room temperature.
1.3.3 pH is detected
This product sample 1 part (being accurate to 0.1g) is weighed, is added through boiling 9 parts of water of laboratory after cooling, and constantly stir
It mixes to uniform, is cooled to set point of temperature, for use.
PH meter is corrected by instrument operation instruction, two standard buffer solutions is selected, is corrected at a temperature of defined.
After instrumental correction, it is rinsed with water electrode first, and filter paper blots, and then electrode is carefully inserted into sample, makes electrode
One end submerges, and reading is recorded after pH meter stable reading.PH value measurement result is indicated with the average value measured twice, is accurate to
0.1。
As a result with analysis
2.1 organoleptic indicators detect
As a result it see the table below, as seen from table, the snake gourd fruit pulp skin whitener appearance developed is ivory buff lotion, glossy, cream
Body exquisiteness, uniformity meet every regulation of QB/T18572004 moisturizing creams.
Table 3-12 snake gourd fruit pulp skin whitener organoleptic detection index results
After physics and chemistry Indexs measure snake gourd fruit pulp skin whitener is kept for 24 hours in the constant incubator of (40 ± 1) DEG C, restore extremely
Without water-oil separating phenomenon after room temperature, meets and provided under the resistance to hot-activity of QB/T18572004 moisturizing creams；It is kept at -5 DEG C~-10 DEG C
After for 24 hours, without water-oil separating phenomenon after restoring to room temperature, meets and provided under the cold-resistant item of QB/T18572004 moisturizing creams；PH value
It is 7.44 ± 0.05, meets the regulation of the pH items lower 4.0~8.5 of QB/T18572004 moisturizing creams.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (3)
1. a kind of snake gourd fruit pulp skin whitener, which is characterized in that the raw material including following weight ratio is prepared, oil phase raw material：Firmly
Resin acid 15%, hexadecanol 2%, isopropyl palmitate 4%, lanolin 2%, methyl hydroxybenzoate 0.1%；Aqueous Phase Raw Material：Three ethyl alcohol
Amine 1.9%, glycerine 8%, azone 1%, water 65%, snakegourd fruit flesh extract 1%.
2. a kind of preparation process of snake gourd fruit pulp skin whitener, which is characterized in that by oil phase raw material：Stearic acid 15%, hexadecanol 2%,
Isopropyl palmitate 4%, lanolin 2%, methyl hydroxybenzoate 0.1% are in 80 DEG C of emulsified 45min, Aqueous Phase Raw Material：Triethanolamine
1.9%, glycerine 8%, azone 1%, water 65%, snakegourd fruit flesh extract 1% are in 90 DEG C of emulsified 45min, after the two is homogeneous,
Aqueous Phase Raw Material is added in four-necked bottle, magnetic stirring apparatus is started, control rotating speed is 3000r/min, is slowly added into oil phase raw material,
15min is stirred, stops heating, essence is added when temperature is down to 40 to 45 DEG C, is sufficiently stirred to obtain snake gourd fruit pulp skin whitener.
3. the preparation method of the snakegourd fruit flesh extract of snake gourd fruit pulp skin whitener as described in right 1, which is characterized in that including walking as follows
Suddenly：Snakegourd fruit flesh 70g is taken, adds 10 times of amount water, impregnates 30min, 1h is heated to reflux at 95 DEG C, filter, the dregs of a decoction and filter paper add 10
Times amount water repeats extraction 2 times, filtering, and filtrate merges, concentrates and be settled in 100mL volumetric flasks and preserve, and obtains the extraction of snakegourd fruit flesh
Object.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810599368.2A CN108553368A (en) | 2018-06-12 | 2018-06-12 | A kind of snake gourd fruit pulp skin whitener and its preparation process |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111317691A (en) * | 2020-02-12 | 2020-06-23 | 南京中医药大学 | Trichosanthes kirilowii flesh total yellow pigment with whitening effect and preparation method and application thereof |
| CN111956550A (en) * | 2020-08-27 | 2020-11-20 | 荣鼎(广东)生物科技有限公司 | Skin-moistening cream with sun-blocking function and preparation method thereof |
| CN114306188A (en) * | 2020-12-31 | 2022-04-12 | 淮阴工学院 | Preparation method of whitening and inflammation diminishing mask liquid |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105106039A (en) * | 2015-09-17 | 2015-12-02 | 南京林业大学 | Method for preparing proanthocyanidin whitening sunscreen cream |
| CN105708752A (en) * | 2016-01-25 | 2016-06-29 | 夏继英 | Sunscreen cream |
-
2018
- 2018-06-12 CN CN201810599368.2A patent/CN108553368A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105106039A (en) * | 2015-09-17 | 2015-12-02 | 南京林业大学 | Method for preparing proanthocyanidin whitening sunscreen cream |
| CN105708752A (en) * | 2016-01-25 | 2016-06-29 | 夏继英 | Sunscreen cream |
Non-Patent Citations (1)
| Title |
|---|
| 徐翠翠等: "瓜蒌瓤提取物对酪氨酸酶抑制作用的研究", 《四川农业大学学报》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111317691A (en) * | 2020-02-12 | 2020-06-23 | 南京中医药大学 | Trichosanthes kirilowii flesh total yellow pigment with whitening effect and preparation method and application thereof |
| CN111956550A (en) * | 2020-08-27 | 2020-11-20 | 荣鼎(广东)生物科技有限公司 | Skin-moistening cream with sun-blocking function and preparation method thereof |
| CN114306188A (en) * | 2020-12-31 | 2022-04-12 | 淮阴工学院 | Preparation method of whitening and inflammation diminishing mask liquid |
| CN114306188B (en) * | 2020-12-31 | 2023-09-29 | 淮阴工学院 | Preparation method of whitening and anti-inflammatory mask liquid |
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Application publication date: 20180921 |