Pet medicated shampoo and preparation method thereof
Technical field
The present invention relates to pet daily cosmetics detergent applications, more particularly to a kind of to have prevention and treatment pet skin
The medicated shampoo and preparation method thereof of sick function.
Background technology
With modern people's improvement of living standard, raising pet has been a kind of leisure way for people.However
For pet while bringing joy to each family, pet skin disease but causes the worry of people.Skin disease is a kind of serious danger
The disease of evil pet dog health, there are many type, and the cause of disease is also complicated various, thereby increases and it is possible to be broadcast to the owner of pet.
Currently, the ointment and lotion of many treatment pet skin diseases are when in use, and it is cumbersome, it needs to dote on to love and subtracts
Hair, destroys the aesthetic appearance of pet, and can only immunotherapy targeted autoantibody infected zone, be unable to large area use, to pet body its
Its region cannot play prevention effect.CN201710903013.3 disclose it is a kind of by ketoconazole, metronidazole is compound and mixture table
A ointment prepared by face activating agent, though have certain curative effect for pet fungal infection skin disease, directed toward bacteria and
Fungi compound infection type skin disease, therapeutic effect is poor, has certain limitation, and be unable to large-area applications.
In view of the above circumstances, developing a has the function of prevention and treatment pet skin disease, easy to use and have both simultaneously
The medicated shampoo of Pet fur nursing seems that meaning is particularly important.
Invention content
The present invention provides one kind having the function of prevention and treatment pet skin disease, easy to use and have both pet skin simultaneously
The pet medicated shampoo and preparation method thereof of hair nursing, can solve one or more of above-mentioned prior art problem.
According to an aspect of the invention, there is provided a kind of pet with prevention and treatment pet skin disease function is medicinal
Shampoo, using following percentage of weight formula:15~25 parts of anion surfactant, 5~15 parts of nonionic surfactant,
2~10 parts of moisturizer, 0.5~5 part of conditioner, 2~10 parts of bleeding agent, 0.5~2 part of antibacterial agent, 0.5~3 part of antifungal agent,
0.1~1 part of 0.5~5 part of nutritional agents, 0.5~4 part of thickener, 0.1~1 part of chelating agent and preservative, remaining deal are deionization
Water.
Further, anion surfactant be selected from sodium lauroyl glutamate, sodium sulfate of polyethenoxy ether of fatty alcohol,
ɑ-one or both of alkene sulfonate and lauryl sodium sulfate.
Further, nonionic surfactant is selected from fatty alcohol polyoxyethylene ether, cocoanut fatty acid diethanolamide
One or both of with alcohol ether glucoside.
Further, the one kind or two of moisturizer in trimethylglycine, trehalose, glycerine and 1,3-BDO
Kind.
Further, conditioner is in guar hydroxypropyltrimonium ammonium chloride, Polyquaternium-10 and polyquaternium -7
One or two.
Further, bleeding agent is selected from absolute ethyl alcohol and 1, one or both of bis- propyl alcohol of 2-.
Further, antibacterial agent is selected from the one or two of chlorohexidene, chlorhexidine gluconate and triclosan.
Further, antifungal agent is selected from the one or two of nitric acid miaow chaff azoles, Terbinafine and ketoconazole.
Further, nutritional agents is selected from the one or two of oat extract, vitamin B5, vitamin B6 and vitamin B3
Further, thickener is selected from hydroxyethyl cellulose, carboxymethyl cellulose, crosslink propylene acid ester copolymer and xanthan
The one or two of glue.
Further, chelating agent is disodium ethylene diamine tetraacetate.
Further, preservative is selected from the one or two of methylisothiazolinone, dihydroxymethyl glycolylurea and Phenoxyethanol.
It is according to the present invention and on the other hand, provide it is a kind of have prevention and treatment pet skin disease function pet medicine
With the preparation method of shampoo, include the following steps:
(1) anion surfactant, nonionic surfactant, chelating agent and deionized water are mixed in mulser
Uniformly, controlled at 50 DEG C~70 DEG C in reaction process.
(2) it is 40 DEG C of condition to keep temperature, and conditioner, bleeding agent, antibacterial agent, antifungal agent and thickener are added
It is stirred evenly in mulser.
(3) temperature of mulser is down to room temperature, moisturizer, nutritional agents and preservative is added in mulser and thoroughly stirred
Uniformly, pet medicated shampoo is made.
Compared with prior art, beneficial effects of the present invention are:
1. the pet medicated shampoo of the present invention, easy to use, large area use can be carried out to pet, be not necessarily to shaving, not shadow
Ring pet grooming appearance, can pre- bacteriological protection and fungal infection, to which pre- anti-pet causes skin disease because of bacterium or fungal infection.
2. the pet medicated shampoo of the present invention is to due to fungal infection, bacterium infection and fungi and bacteria mixed infection type
Pet skin disease has good therapeutic effect.
3. the present invention pet medicated shampoo also have without pigment, without essence, irritation is low and raw material process is green
The advantages that environmentally friendly.
Specific implementation mode
Invention is further elaborated below by specific implementation mode.
Embodiment 1
(1) 12.0g sodium sulfate of polyethenoxy ether of fatty alcohol, 4.5g lauryl sodium sulfate, 3.0g lauroyl paddy are weighed
Propylhomoserin sodium, 2.0g cocoanut fatty acid diethanolamides, 0.1g disodium EDTAs and 67.0g deionized waters, in breast
It is uniformly mixed in change machine, temperature controls within the scope of 50 DEG C~70 DEG C;
(2) keep temperature be 40 DEG C, weigh 1.0g polyquaterniums -7,0.5g guar hydroxypropyltrimoniums ammonium chloride,
2.0g absolute ethyl alcohol, 1.0g chlorhexidine gluconates, 0.7g ketoconazoles and 0.7g sodium carboxymethylcelluloses are added in mulser and stir
It mixes uniformly;
(3) machine temperature to be emulsified is down to room temperature, and breast is added in 2.0g glycerine, 0.7g oats and 0.2g methylisothiazolinones
It is thoroughly stirred evenly in change machine, pet medicated shampoo is made.
Embodiment 2
(1) weigh 18.0g sodium sulfate of polyethenoxy ether of fatty alcohol, 1.0g lauryl sodium sulfate, 4.5g alcohol ether glucosides,
0.1g disodium EDTAs and 65.9g deionized waters are uniformly mixed in mulser, and temperature is controlled at 50 DEG C~70 DEG C
In range;
(2) keep temperature be 40 DEG C, weigh 1.5g Polyquaternium-10s, 0.3g guar hydroxypropyltrimoniums ammonium chloride,
Emulsification is added in bis- propyl alcohol of 1.9g 1,2-, 1.5g chlorhexidine gluconates, 0.6g nitric acid miaow chaff azoles and 0.6g sodium hydroxyethyl celluloses
It is stirred evenly in machine;
(3) wait for that temperature is down to room temperature, by 2.0g 1,3-BDOs, 1.1g oats, 0.8g vitamin B3s and 0.2g dihydroxy first
Base glycolylurea is added in mulser and thoroughly stirs evenly, and pet medicated shampoo is made.
Embodiment 3
(1) 13.0g sodium sulfate of polyethenoxy ether of fatty alcohol, 3.0g lauryl sodium sulfate, 4.0g- alkene sulfonic acids are weighed
Salt, 2.0g fatty alcohol polyoxyethylene ether, 1.3g coco-nut oil fatty acids diethanol amine, 0.1g disodium EDTAs and
66.0g deionized waters are uniformly mixed in mulser, and temperature controls within the scope of 50 DEG C~70 DEG C;
(2) keep temperature be 40 DEG C, weigh 1.4g Polyquaternium-10s, 0.4g guar hydroxypropyltrimoniums ammonium chloride,
1.1g absolute ethyl alcohols, 0.8g 1, bis- propyl alcohol of 2-, 1.4g chlorhexidine gluconates, 0.9g Terbinafines and 0.9g cross-linked acrylic acids
Ester copolymer is added in mulser and stirs evenly;
(3) machine temperature to be emulsified is down to room temperature, by 1.3g glycerine, 0.9g trimethylglycines, 0.4g oats, 0.5g dimension lifes
Thoroughly stirring is added in mulser in plain B3,0.4g vitamin B6,0.1g dihydroxymethyls glycolylurea and 0.1g methylisothiazolinones
It is even, pet medicated shampoo is made.
Embodiment 4
The product that Examples 1 to 3 is obtained carries out treatment pet skin characteristic of disease respectively can be with traditional performance detection.
Treat pet skin disease performance test.
(1) experimental animal:Fungal infection dermatoses and bacterium, fungi mixing are suffered from the Animal Shelter institute of somewhere after diagnosing
The wandering dog of infective factors, illness dog neck, abdomen be rubescent, itching, has scurf, there is useless fellow in affected part, and different journeys occur
The depilation of degree.
(2) experimental subjects:Illness dog is divided into 5 groups at random, every group 10,1-3 groups are experimental group, and the 4th group is control
Example 1, the 5th group is blank control group, i.e. reference examples 2.1-3 groups are treated with embodiment 1, embodiment 2, embodiment 3 respectively,
Reference examples 1 are treated with commercially available golden dipping shampoo, and reference examples 2 are blank control group.
(3) experimental method:It tests 1-3 groups and reference examples 1 and uses corresponding shampoo cleans daily 1 time, continue 12 days, compare
Example 2 is without any processing, and quarantines to all grouping wandering dogs.
(4) experimental result summarizes such as table one.
Table one, treatment pet skin disease performance test
Analysis of experimental results:The present invention is to pet because of bacterium infection, fungal infection and bacterium and fungi mixed infection skin
Skin disease has apparent therapeutic effect, and the medicinal shampoo for pets effect made from embodiment 1 is best.
Traditional performance test experience.
(1) test specimen:By the pet medicated shampoo obtained by embodiment 1-3.
(2) experimental animal:Somewhere Animal Shelter institute wandering dog 21, is randomly divided into 3 groups, every group 7, corresponds to reality respectively
Apply example 1, embodiment 2, embodiment 3.
(3) experimental result summarizes such as table two.
Table two, traditional performance test experience result
Test specimen |
Fur compliance |
PH value |
Cleannes |
Irritation |
Essence and pigment |
Embodiment 1 |
It is more smooth |
6.23 |
Totally |
Without apparent phenomenon |
Nothing |
Embodiment 2 |
It is smooth |
6.13 |
Totally |
Without apparent phenomenon |
Nothing |
Embodiment 3 |
It is smooth |
6.15 |
Totally |
Without apparent phenomenon |
Nothing |
Analysis of experimental results:One kind provided by the invention is with prevention and treatment pet skin disease medicated shampoo with preferably
Hair-care performance, do not stimulate mildly, without essence, non-pigment.
The above is only some embodiments of the present invention.For those of ordinary skill in the art, it is not taking off
Under the premise of conceiving from the invention, various modifications and improvements can be made, these are all within the scope of protection of the present invention.