CN108542852A - A kind of skin is releived composition and preparation method thereof - Google Patents

A kind of skin is releived composition and preparation method thereof Download PDF

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Publication number
CN108542852A
CN108542852A CN201810731246.4A CN201810731246A CN108542852A CN 108542852 A CN108542852 A CN 108542852A CN 201810731246 A CN201810731246 A CN 201810731246A CN 108542852 A CN108542852 A CN 108542852A
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China
Prior art keywords
extract
skin
component
composition
releived
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CN201810731246.4A
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Inventor
闫吉
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Shenzhen Ming Run Biological Technology Co Ltd
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Shenzhen Ming Run Biological Technology Co Ltd
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Priority to CN201810731246.4A priority Critical patent/CN108542852A/en
Publication of CN108542852A publication Critical patent/CN108542852A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

It releives composition and preparation method thereof the invention discloses a kind of skin.The skin releive composition include following weight percent raw material：Propylene glycol 20 33%, butanediol 6 12%, Notogineng Extract 0.5 1.2%, cinnamomum cassia extract 0.5 1.2%, extractive of pubescent angelica root coumarin 0.5 1.2%, sarranine flower extract 0.5 1.2%, angelica extract 0.5 1.2%, Olibanum extract 0.5 1.2%, Herba speranskiae tuberculatae extract 0.5 1.2%, hyaluronic acid 0.5 1.2%, pyrrolidone sodium carboxylate 0.5 1.2%, dipotassium glycyrrhizinate 0.5 1.2%, EDETATE SODIUM 0.5 1%, methyl hydroxybenzoate 0.05 0.15%, the water of surplus.The skin of present invention composition of releiving is rich in a variety of herbaceous plant quintessences, can deep layer assign skin cell living, it is as before to repair human skin, have releive, moisturizing, moisturizing, nourishing, the multiple efficacies such as moist；Application method is simple, after cleaning skin, takes this product to be applied to body skin in right amount, softly looping is massaged into absorption；Preparation process is simple, is advantageously implemented industrialized production.

Description

A kind of skin is releived composition and preparation method thereof
Technical field
The present invention relates to cosmetic technical field, specifically a kind of skin is releived composition and preparation method thereof.
Background technology
Skin is human body largest organ, it is covered in entire human body surface.Skin has barrier function and moisture retention, maintains The barrier function and moisture retention of skin are the most basic functions of skin nursing class cosmetics.Maintain the barrier function of skin in addition to it Except the integrality of institutional framework, the hydration moisture-keeping functions of skin are also depended on.Whole body moisture major storage in skin, accounts for complete The 18-20% of body.At present individual's skin care item in the market can effectively allergy-relieving product it is seldom, and replenishing water and preserving moisture effect is still It need to further increase.Therefore, on the basis of safe and healthy, prepared by research has effects that releive, the composition of replenishing water and preserving moisture, And apply it in personal skin care item, there is practical significance.
Invention content
It releives composition and preparation method thereof the purpose of the present invention is to provide a kind of skin, to solve above-mentioned background technology The problem of middle proposition.
To achieve the above object, the present invention provides the following technical solutions：
A kind of skin is releived composition, and the raw material of following weight percent is included：Propylene glycol 20-33%, butanediol 6-12%, Radix Notoginseng Extract 0.5-1.2%, cinnamomum cassia extract 0.5-1.2%, extractive of pubescent angelica root coumarin 0.5-1.2%, sarranine flower extract 0.5-1.2%, when Return extract 0.5-1.2%, Olibanum extract 0.5-1.2%, Herba speranskiae tuberculatae extract 0.5-1.2%, hyaluronic acid 0.5-1.2%, pyrrole Pyrrolidone carboxylic acid's sodium 0.5-1.2%, dipotassium glycyrrhizinate 0.5-1.2%, EDETATE SODIUM 0.5-1%, methyl hydroxybenzoate 0.05-0.15%, it is remaining The water of amount.
As a further solution of the present invention：Include the raw material of following weight percent：Propylene glycol 30%, butanediol 10%, Notogineng Extract 1%, cinnamomum cassia extract 1%, extractive of pubescent angelica root coumarin 1%, sarranine flower extract 1%, angelica extract 1%, Olibanum extract 1%, Herba speranskiae tuberculatae extract 1%, hyaluronic acid 1%, pyrrolidone sodium carboxylate 1%, dipotassium glycyrrhizinate 1%, EDETATE SODIUM 0.9%, oxybenzene Methyl esters 0.1%, the water of surplus.
A kind of skin is releived the preparation method of composition, is included the following steps：
（1）Water, propylene glycol, butanediol, hyaluronic acid, pyrrolidone sodium carboxylate and EDETATE SODIUM are weighed according to above-mentioned formula, is made For component A；Notogineng Extract, cinnamomum cassia extract, extractive of pubescent angelica root coumarin, sarranine flower extract, angelica extract, Olibanum extract, Herba speranskiae tuberculatae extract and dipotassium glycyrrhizinate, as component B；Methyl hydroxybenzoate is weighed according to above-mentioned formula, as component C；
（2）Component A is put into agitating device, and stirs 5-15min at 70-90 DEG C, then vacuumizes cooling；
（3）After upper step gains are cooled to 55-65 DEG C, component B is added, stirring to material is all dissolved；
（4）When upper step gains are cooled to 40 DEG C or less, component C is added, is thoroughly mixed to material and all dissolves；
（5）By upper step gains inspection, discharges after detection is qualified, obtain semi-finished product and store；
（6）Microorganism detection is carried out, after detection is qualified, carries out filling, packaging to get finished product.
As a further solution of the present invention：Step（2）Component A is put into agitating device, and is stirred at 80 DEG C Then 10min vacuumizes cooling.
As a further solution of the present invention：Step（3）After upper step gains are cooled to 60 DEG C, component B is added, stirring is extremely Material all dissolves.
As a further solution of the present invention：Step（4）When upper step gains are cooled to 35 DEG C or less, component C is added, fills Divide to be stirred to material and all dissolve.
As a further solution of the present invention：In step（1）Before, first clean and sterilize apparatus needed for production.
Compared with prior art, the beneficial effects of the invention are as follows：
The skin of the present invention releives composition rich in a variety of herbaceous plant quintessences, and energy deep layer assigns skin cell living, repairs human body skin Skin is as before, have releive, moisturizing, moisturizing, nourishing, the multiple efficacies such as moist；Application method is simple, after cleaning skin, takes this product It is applied to body skin in right amount, softly looping is massaged into absorption；Preparation process is simple, is advantageously implemented industrialized production.
Specific implementation mode
The technical solution of this patent is described in more detail With reference to embodiment.
Embodiment 1
A kind of skin is releived composition, and the raw material of following weight percent is included：Propylene glycol 20-33%, butanediol 6-12%, Radix Notoginseng Extract 0.5-1.2%, cinnamomum cassia extract 0.5-1.2%, extractive of pubescent angelica root coumarin 0.5-1.2%, sarranine flower extract 0.5-1.2%, when Return extract 0.5-1.2%, Olibanum extract 0.5-1.2%, Herba speranskiae tuberculatae extract 0.5-1.2%, hyaluronic acid 0.5-1.2%, pyrrole Pyrrolidone carboxylic acid's sodium 0.5-1.2%, dipotassium glycyrrhizinate 0.5-1.2%, EDETATE SODIUM 0.5-1%, methyl hydroxybenzoate 0.05-0.15%, it is remaining The water of amount.
A kind of skin is releived the preparation method of composition, is included the following steps：（1）It first cleans and sterilizes needed for production and use Tool.Then water, propylene glycol, butanediol, hyaluronic acid, pyrrolidone sodium carboxylate and EDETATE SODIUM are weighed according to above-mentioned formula, made For component A；Notogineng Extract, cinnamomum cassia extract, extractive of pubescent angelica root coumarin, sarranine flower extract, angelica extract, Olibanum extract, Herba speranskiae tuberculatae extract and dipotassium glycyrrhizinate, as component B；Methyl hydroxybenzoate is weighed according to above-mentioned formula, as component C；（2）By group Divide A to be put into agitating device, and stir 5-15min at 70-90 DEG C, then vacuumizes cooling；（3）Upper step gains are cooled to After 55-65 DEG C, component B is added, stirring to material is all dissolved；（4）When upper step gains are cooled to 40 DEG C or less, component is added C is thoroughly mixed to material and all dissolves；（5）By upper step gains inspection, discharges after detection is qualified, obtain semi-finished product simultaneously Storage；（6）Microorganism detection is carried out, after detection is qualified, carries out filling, packaging to get finished product.
Application method：After cleaning skin, this product is taken to be applied to body skin in right amount（Whole body is applicable in）, softly loop and be massaged into Absorption.
Embodiment 2
A kind of skin is releived composition, and the raw material of following weight percent is included：Propylene glycol 20-33%, butanediol 6-12%, Radix Notoginseng Extract 0.5-1.2%, cinnamomum cassia extract 0.5-1.2%, extractive of pubescent angelica root coumarin 0.5-1.2%, sarranine flower extract 0.5-1.2%, when Return extract 0.5-1.2%, Olibanum extract 0.5-1.2%, Herba speranskiae tuberculatae extract 0.5-1.2%, hyaluronic acid 0.5-1.2%, pyrrole Pyrrolidone carboxylic acid's sodium 0.5-1.2%, dipotassium glycyrrhizinate 0.5-1.2%, EDETATE SODIUM 0.5-1%, methyl hydroxybenzoate 0.05-0.15%, it is remaining The water of amount.
A kind of skin is releived the preparation method of composition, is included the following steps：（1）It first cleans and sterilizes needed for production and use Tool.Then water, propylene glycol, butanediol, hyaluronic acid, pyrrolidone sodium carboxylate and EDETATE SODIUM are weighed according to above-mentioned formula, made For component A；Notogineng Extract, cinnamomum cassia extract, extractive of pubescent angelica root coumarin, sarranine flower extract, angelica extract, Olibanum extract, Herba speranskiae tuberculatae extract and dipotassium glycyrrhizinate, as component B；Methyl hydroxybenzoate is weighed according to above-mentioned formula, as component C；（2）By group Divide A to be put into agitating device, and stir 5-15min at 70-90 DEG C, then vacuumizes cooling；（3）Upper step gains are cooled to After 55-65 DEG C, component B is added, stirring to material is all dissolved；（4）When upper step gains are cooled to 40 DEG C or less, component is added C is thoroughly mixed to material and all dissolves；（5）By upper step gains inspection, discharges after detection is qualified, obtain semi-finished product simultaneously Storage；（6）Microorganism detection is carried out, after detection is qualified, carries out filling, packaging to get finished product.
Application method：After cleaning skin, this product is taken to be applied to body skin in right amount（Whole body is applicable in）, softly loop and be massaged into Absorption.
Embodiment 3
A kind of skin is releived composition, and the raw material of following weight percent is included：Propylene glycol 30%, butanediol 10%, Radix Notoginseng extraction It is object 1%, cinnamomum cassia extract 1%, extractive of pubescent angelica root coumarin 1%, sarranine flower extract 1%, angelica extract 1%, Olibanum extract 1%, deep Careless extract 1%, hyaluronic acid 1%, pyrrolidone sodium carboxylate 1%, dipotassium glycyrrhizinate 1%, EDETATE SODIUM 0.9%, methyl hydroxybenzoate 0.1%, the water of surplus.
A kind of skin is releived the preparation method of composition, is included the following steps：（1）It first cleans and sterilizes needed for production and use Tool.Then water, propylene glycol, butanediol, hyaluronic acid, pyrrolidone sodium carboxylate and EDETATE SODIUM are weighed according to above-mentioned formula, made For component A；Notogineng Extract, cinnamomum cassia extract, extractive of pubescent angelica root coumarin, sarranine flower extract, angelica extract, Olibanum extract, Herba speranskiae tuberculatae extract and dipotassium glycyrrhizinate, as component B；Methyl hydroxybenzoate is weighed according to above-mentioned formula, as component C；（2）By group Divide A to be put into agitating device, and stir 10min at 80 DEG C, then vacuumizes cooling.（3）Upper step gains are cooled to 60 DEG C Afterwards, component B is added, stirring to material is all dissolved.（4）When upper step gains are cooled to 35 DEG C or less, component C is added, fully It is stirred to material and all dissolves.（5）By upper step gains inspection, discharges after detection is qualified, obtain semi-finished product and store； （6）Microorganism detection is carried out, after detection is qualified, carries out filling, packaging to get finished product.
Application method：After cleaning skin, this product is taken to be applied to body skin in right amount（Whole body is applicable in）, softly loop and be massaged into Absorption.
Experimental example
One, hygienic chemistry index is shown in Table 1.
1 hygienic chemistry index of table
Skin prepared by 1-3 of embodiment of the present invention composition of releiving meets hygienic chemistry index.
Two, microbiological indicator is shown in Table 2.
2 microbiological indicator of table
Skin prepared by 1-3 of embodiment of the present invention composition of releiving meets microbiological indicator.
3 method of inspection of table
The principle of the present invention：In inventive formulation, solvent is water and butanediol；Moisturizer is propylene glycol, hyaluronic acid and pyrroles Alkanone carboxylic acid sodium；Skin conditioning agent is Notogineng Extract, cinnamomum cassia extract, extractive of pubescent angelica root coumarin, sarranine flower extract, Radix Angelicae Sinensis extraction Object, Olibanum extract, Herba speranskiae tuberculatae extract and dipotassium glycyrrhizinate；Chelating agent is EDETATE SODIUM；Preservative is methyl hydroxybenzoate.
The better embodiment of this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party Formula, one skilled in the relevant art within the scope of knowledge, can also be under the premise of not departing from this patent objective Various changes can be made.

Claims (7)

  1. The composition 1. a kind of skin is releived, which is characterized in that include the raw material of following weight percent：Propylene glycol 20-33%, fourth Glycol 6-12%, Notogineng Extract 0.5-1.2%, cinnamomum cassia extract 0.5-1.2%, extractive of pubescent angelica root coumarin 0.5-1.2%, safron extraction Object 0.5-1.2%, angelica extract 0.5-1.2%, Olibanum extract 0.5-1.2%, Herba speranskiae tuberculatae extract 0.5-1.2%, hyalomitome Sour 0.5-1.2%, pyrrolidone sodium carboxylate 0.5-1.2%, dipotassium glycyrrhizinate 0.5-1.2%, EDETATE SODIUM 0.5-1%, methyl hydroxybenzoate 0.05-0.15%, the water of surplus.
  2. The composition 2. skin according to claim 1 is releived, which is characterized in that include the raw material of following weight percent： Propylene glycol 30%, butanediol 10%, Notogineng Extract 1%, cinnamomum cassia extract 1%, extractive of pubescent angelica root coumarin 1%, sarranine flower extract 1%, when Return extract 1%, Olibanum extract 1%, Herba speranskiae tuberculatae extract 1%, hyaluronic acid 1%, pyrrolidone sodium carboxylate 1%, dipotassium glycyrrhizinate 1%, EDETATE SODIUM 0.9%, methyl hydroxybenzoate 0.1%, the water of surplus.
  3. 3. a kind of preparation method for composition of being releived according to any skins of claim 1-2, which is characterized in that including with Lower step：
    （1）Water, propylene glycol, butanediol, hyaluronic acid, pyrrolidone sodium carboxylate and EDETATE SODIUM are weighed according to above-mentioned formula, is made For component A；Notogineng Extract, cinnamomum cassia extract, extractive of pubescent angelica root coumarin, sarranine flower extract, angelica extract, Olibanum extract, Herba speranskiae tuberculatae extract and dipotassium glycyrrhizinate, as component B；Methyl hydroxybenzoate is weighed according to above-mentioned formula, as component C；
    （2）Component A is put into agitating device, and stirs 5-15min at 70-90 DEG C, then vacuumizes cooling；
    （3）After upper step gains are cooled to 55-65 DEG C, component B is added, stirring to material is all dissolved；
    （4）When upper step gains are cooled to 40 DEG C or less, component C is added, is thoroughly mixed to material and all dissolves；
    （5）By upper step gains inspection, discharges after detection is qualified, obtain semi-finished product and store；
    （6）Microorganism detection is carried out, after detection is qualified, carries out filling, packaging to get finished product.
  4. The preparation method of composition 4. skin according to claim 3 is releived, which is characterized in that step（2）Component A is put Enter in agitating device, and stir 10min at 80 DEG C, then vacuumizes cooling.
  5. The preparation method of composition 5. skin according to claim 3 is releived, which is characterized in that step（3）Obtained by upper step After object is cooled to 60 DEG C, component B is added, stirring to material is all dissolved.
  6. The preparation method of composition 6. skin according to claim 3 is releived, which is characterized in that step（4）Obtained by upper step When object is cooled to 35 DEG C or less, component C is added, is thoroughly mixed to material and all dissolves.
  7. The preparation method of composition 7. skin according to claim 3 is releived, which is characterized in that in step（1）Before, first Apparatus needed for cleaning and disinfection production.
CN201810731246.4A 2018-07-05 2018-07-05 A kind of skin is releived composition and preparation method thereof Pending CN108542852A (en)

Priority Applications (1)

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CN201810731246.4A CN108542852A (en) 2018-07-05 2018-07-05 A kind of skin is releived composition and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108096153A (en) * 2018-02-26 2018-06-01 嘉嵘国际生物科技（深圳）有限公司 A kind of skin conditioning article and preparation method thereof
CN114632040A (en) * 2022-03-15 2022-06-17 宝萃生物科技有限公司 Composition with relieving effect and preparation and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106691973A (en) * 2017-02-16 2017-05-24 广州市爱百伊生物技术有限公司 Age-reversing skin bottom rejuvenating care product and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106691973A (en) * 2017-02-16 2017-05-24 广州市爱百伊生物技术有限公司 Age-reversing skin bottom rejuvenating care product and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
国家药品监督管理局: ""静品轩舒源套-舒源活肌液", 《HTTP://125.35.6.80:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20180407230143A35RY&NID=20180407230143A35RY》 *
王建新等: "《化妆品植物原料大全》", 30 June 2012 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108096153A (en) * 2018-02-26 2018-06-01 嘉嵘国际生物科技（深圳）有限公司 A kind of skin conditioning article and preparation method thereof
CN114632040A (en) * 2022-03-15 2022-06-17 宝萃生物科技有限公司 Composition with relieving effect and preparation and application thereof
CN114632040B (en) * 2022-03-15 2022-09-13 宝萃生物科技有限公司 Composition with relieving effect and preparation and application thereof

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