CN108542844A - A kind of Tibetan medicine skin care compositions and its application - Google Patents
A kind of Tibetan medicine skin care compositions and its application Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9761—Cupressaceae [Cypress family], e.g. juniper or cypress
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of Tibetan medicine skin care compositions, are prepared by the Tibetan medicine of following parts by weight：1 10 parts of Rhizoma Acori Calami, 1 10 parts of safron, 1 10 parts of Chinese juniper leaf, 1 10 parts of German tamarisk, 1 10 parts of lanatechead saussurea herb with flower.The present invention has the function of antipyretic and itching-stopping, enhancing skin elasticity, improvement or eliminates fash and eczema, has mitigation for outmoded wound, extremity numbness, rheumatoid arthritis etc..
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of Tibetan medicine skin care compositions and its application.
Background technology
Tibetan medicine is to absorb extensively, merging traditional Chinese medicine and pharmacy, the basis of Indian Medicinal and big dietitian's pharmacy scheduling theory
On, unique medicine systems are formed by by long-term practice, have the history of more than one thousand years so far, be China it is more complete, compared with
One of influential ethnic drug.Tibetan medicine is distributed mainly on Qinghai-Tibet Platean.Here there are complicated and unique natural conditions, formed
Colourful plant resources type is sequentially distributed from the tropical monsoon forest of Southeast Tibet to the grassland for hiding northern vastness
The floristics in the torrid zone, subtropical zone, temperate zone, frigid zone can be reflected by, and Tibetan area vascular plant type is up to 6144 according to information
Kind, occupy the 4th, the whole nation.Since the dawn of human civilization, Tibetan area is exactly a big treasure-house of China's medicinal plant, according to the preliminary statistics, wild medicine
There are thousand kinds or more with plant resources, wherein cordyceps sinensis, fritillaria, Radix Notoginseng, Rhizoma Gastrodiae, ganoderma lucidum etc. is the rare medicine to enjoy a good market both at home and abroad
Material；Cephalotaxus mannii, Chinese yew, Podophyllum emodi var chinense, Dysosma versipellis, radix macrotomiae, very thin theezan tea, rattlebush etc., which are one kind, potentiality to be exploited
Anti-cancer medicinal plants.In addition, also traditional Chinese medicine fructus amomi, uncaria, bark of ash, the root bark of tree peony, pawpaw, Paris polyphylla, Chinese ephedra, peach kernel, the coptis,
All kinds of medicinal materials such as radix bupleuri, Radix Angelicae Sinensis, Radix Astragali, rough gentian, Radix Codonopsis, the rhizome of Chinese monkshood, rheum officinale, barberry, lanatechead saussurea herb with flower, Schisandra chinensis.With life
Horizontal raising, consumer have higher requirement, each manufacturer actively to find new characteristic raw material to meet cosmetic product
The market demand, in this background, Tibetan medicine have been introduced into cosmetic industry.
Invention content
The technical problem to be solved in the present invention is to provide a kind of Tibetan medicine skin care compositions and its applications.
The specific technical solution for solving above-mentioned technical problem is as follows：
A kind of Tibetan medicine skin care compositions, is prepared by the Tibetan medicine of following parts by weight：1-10 parts of Rhizoma Acori Calami, safron 1-
10 parts, 1-10 parts of Chinese juniper leaf, 1-10 parts of German tamarisk, 1-10 parts of lanatechead saussurea herb with flower.
Further, the Tibetan medicine skin care compositions is prepared by the Tibetan medicine of following parts by weight：3-7 parts of Rhizoma Acori Calami, kind
2-6 parts of safflower, 4-8 parts of Chinese juniper leaf, 5-8 parts of German tamarisk, 3-6 parts of lanatechead saussurea herb with flower.
Further, the preparation method of the Tibetan medicine skin care compositions is as follows：(1) it decocts：Weigh Rhizoma Acori Calami, sarranine
Flower, the mixing of Chinese juniper leaf, German tamarisk, lanatechead saussurea herb with flower, dry, pulverize, and by mixing medicinal material merging copper pot, deionized water be added not have
Drug, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：
Mixing medicinal material will be decocted to take out, 35-45 DEG C is cooled to, aspergillus is added, stirs evenly, seal；It ferments under the conditions of 10-20 DEG C
5-10 days, obtain fermentation medicinal material；
(3) it extracts：Fermentation medicinal material is placed in copper pot, is added in the ethyl alcohol that volume fraction is 50-95%, uses
The ultrasonication that frequency is 25kHZ-45kHZ 1-10 minutes, then water-bath flows back 1-2 hours under conditions of 90-100 DEG C,
100-500 mesh filter-cloth filterings collect filtrate and filter residue respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, by two
Filtrate obtained by secondary extraction merges；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, in 2-5 DEG C of low temperature item
It is preserved 1-2 days under part, then with aperture 1-2 microns of filter plant pressure filtration, is restored to room temperature to get Tibetan medicine skincare composition
Object.
Further, the grain size crushed in the step (1) is 10-100 mesh.
Further, in the step (2), the additive amount of the aspergillus is the 0.01- for decocting mixing medicinal material weight
0.1%.The present invention using aspergillus ferment, remain Rhizoma Acori Calami, safron, Chinese juniper leaf, German tamarisk, lanatechead saussurea herb with flower functional component and
Activity, active constituent caused by avoiding during the fermentation are lost in.Skin can effectively be enhanced to feeling caused by bacterium, fungi
The immunity of dye can make skin become to lubricate, and moisture is sufficient, high resilience.
Further, in the step (3), the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:(3-7).
The present invention also provides application of the Tibetan medicine skin care compositions in preparing cosmetics, wherein the Tibetan medicine shield
Skin composition dosage be final products weight 0.1-10wt%.
A kind of massage cream includes the component of following mass percentage：Above-mentioned Tibetan medicine skin care compositions 0.1-10%, mine
Oily 15-35%, dimethyl silicone polymer 1-5%, carbonic acid dioctyl ester 1-10%, ceteareth -25 1-3%, PEG/
PPG-30/10 dimethyl silicone polymers 0.5-5%, cetostearyl alcohol 1-5%, cocoyl glucoside 0.1-3%, stearyl alcohol are poly-
- 2 0.5-2% of ether, hydrogenation Sweet Almond Oil 0.1-5%, polyisobutene 0.1-5%, PEG-7 trihydroxy methyl propyl cocounut oil ether
0.1-1%, stearyl alcohol 0.1-3%, sea-buckthorn (HIPPOPHAE RHAMNOIDES) oil 0.1-3%, hydroxy-ethyl acrylate/propylene
Acyl dimethyltaurine sodium copolymer 0.1-0.6%, glycine betaine 0.1-5%, polyalcohol 5-20%, glucan 0.1-3%, water
Surplus.
Further, the polyalcohol is at least one of sorbierite, glycerine, 1,3 butanediols.
The present invention has the advantages that：
The Tibetan medicine skin care compositions of the present invention is made through specific prescription and technique, the single being far longer than before no prescription
The effect of medicine, medicinal material is after the techniques such as decoct, ferment, five tastes cooperation, has that clearing heat and detoxicating, promoting blood circulation and removing blood stasis, to promote skin new
The effects that old metabolism, strengthen immunity.Tibetan medicine skin care compositions is applied and is stopped with heat-clearing in the skin-protection products such as massage cream
Itch, enhance skin elasticity, improvement or the effect for eliminating fash and eczema, for outmoded wound, extremity numbness, rheumatoid arthrosis
Inflammation etc. has mitigation.
Tibetan medicine skin care compositions preparation process combining with fermentation of the present invention and ultrasonic extraction, be greatly improved Rhizoma Acori Calami, kind
Safflower, Chinese juniper leaf, German tamarisk, lanatechead saussurea herb with flower yield of active ingredients.
The antibiotic property of Rhizoma Acori Calami additionally add preservative in Tibetan medicine skin care compositions preparation process of the present invention
Also there can be preferable anti-corrosion preservation effect.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can join
More solito technology carries out.
Rhizoma Acori Calami is the dry rhizome of aroid Rhizoma Acori Calami AcoruscalamusL., Tibetan conventional crude drugs.
China is widely used, and is the important species of integration of drinking and medicinal herbs, first recorded in《Sheng Nong's herbal classic》And it uses till today.In Tibetan area, Rhizoma Acori Calami
Use and history have prodigious value, be listed in level-one Tibetan medicine medicinal material in imminent danger, herb resource lacks.Rhizoma Acori Calami contains
The volatile oil components such as monoterpene, sequiterpene, Phenylpropanoid Glycosides and flavones, quinone, alkaloid, choline, organic acid, amino acid, sugar etc. are non-to be waved
Hair property ingredient, wherein volatile oil component have warm stomach, the effect of anti-inflammatory analgetic.With calm, antibacterial action of calming the nerves.
Safron is irides, is a kind of ancient rare autonomic drug, in China's medicine masterpiece《Compendium of Materia Medica》In
Description safron " it is sweet flat nontoxic, it cures mainly to worry and smoulder, it is unhappy not dissipate；Long food makes us heart happiness, and controls palpitation with fear." safron is rich in
There is promoting blood circulation dredging collateral, removing pattogenic heat from the blood and toxic material from the body blood-nourishing again to build up health, support for all kinds of plant glucosides, sterol and unsaturated fatty acid
Face skin makeup, resolving stagnation for tranquilization adjust refreshing pneumostatic, adjust endocrine curative effect.Its extract has the works such as promoting blood circulation, anti-inflammatory, anti-oxidant
With by improving skin blood cycle, promotion skin metabolism, removing free radical, inhibition melanin deposition, accelerating ecchymose removing
Decoloration, absorption ultraviolet light etc., play whitening, sun-proof, anti-aging function, and to contact dermatitis, seborrheic dermatitis, scabies
Disease, the neurodermatitis of itching have therapeutic effect.
Chinese juniper leaf is the dried leaf of cupressaceae plant needle juniper (Juniperus rigida sieb.et zucc.).Nature and flavor：Taste
It is bitter, puckery, it is cool.It cures mainly：Measles high fever, eczema, tinea sore.Have clear kidney heat, profit as traditional Tibetan medicine containing flavone compound
Urine, dry " Xieri Wusu Symptom ", callus hemostasis and other effects.
German tamarisk is the spray of Tamaricaceae German tamarisk Myricaria germanica (L.) Desv..Distribution Qinghai,
The ground such as Gansu, Shaanxi, Sichuan, Tibet, Shanxi, Yunnan.Its chemical composition mainly contained is：Flavones, quercitin, Quercetin,
Kaempferol, gallic acid etc..It can be used for inducing diaphoresis promoting eruption, dispelling wind and arresting itching cures mainly measles without adequate eruption, arthralgia pain due to rheumatism, ringworm.
Lanatechead saussurea herb with flower is that feverfew Saussurea laniceps spend Saus-surea laniceps Hand.-Mazz. or paddy field saussurea involucrata
The wounded in the battle complete stool of flower S.medusa Maxim.Main product Yunnan, Sichuan, Tibet, Xinjiang, Gansu etc..It is sweet, bitter, temperature.Enter liver, spleen,
Kidney channel.Tonifying kidney and strengthening yang, regulating menstruation, hemostasis.1. controlling impotence, waist and knee is weak, irregular menstruation, uterine bleeding, under band, rheumatic arthritis, and snow
The region between the heart and the diaphragm, toothache.Decoction:3~9g.2. controlling traumatic bleeding, external application is mashed.Mainly contain flavonoids, alkaloids, lignanoids etc.
Ingredient.With the multiple pharmacological effects such as anti-light aging, anti-oxidant, promotion collagen synthesis, radioresistance, anti-inflammatory.
Embodiment 1
A kind of massage cream includes the component of following mass percentage：Tibetan medicine skin care compositions 0.1%, dormant oil 15%,
Dimethyl silicone polymer 1%, carbonic acid dioctyl ester 10%, ceteareth -25 3%, PEG/PPG-30/10 poly dimethyls
Siloxanes 0.5%, cetostearyl alcohol 1%, cocoyl glucoside 3%, stereth -2 2%, hydrogenation Sweet Almond Oil
0.1%, polyisobutene 5%, PEG-7 trihydroxy methyl propyl cocounut oil ether 0.1%, stearyl alcohol 3%, sea-buckthorn (HIPPOPHAE
RHAMNOIDES) oil 0.1%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.6%, glycine betaine 0.1%,
Sorbierite 5%, glucan 3%, water surplus.
The Tibetan medicine skin care compositions is prepared by the Tibetan medicine of following parts by weight：10 parts of Rhizoma Acori Calami, 1 part of safron, thorn
10 parts of CedarLeaves, 1 part of German tamarisk, 10 parts of lanatechead saussurea herb with flower.
The preparation method of the Tibetan medicine skin care compositions is as follows：(1) it decocts：Weigh Rhizoma Acori Calami, safron, Chinese juniper leaf,
German tamarisk, lanatechead saussurea herb with flower mixing, dry, pulverize to 100 mesh, by mixing medicinal material merging copper pot, deionized water be added not have medicine
Object, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will
It decocts mixing medicinal material to take out, is cooled to 45 DEG C, aspergillus is added, the additive amount of the aspergillus is to decoct mixing medicinal material weight
0.01%, it stirs evenly, seals；It ferments 10 days under the conditions of 10 DEG C, obtains fermentation medicinal material；(3) it extracts：Fermentation medicinal material is set
Enter in copper pot, be added in the ethyl alcohol that volume fraction is 50%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:7；It adopts
The ultrasonication 10 minutes for being 25kHZ with frequency, then water-bath flows back 2 hours under conditions of 100 DEG C, 100 mesh filter cloth mistakes
Filtrate and filter residue are collected in filter respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and closed
And；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 2 days under 5 DEG C of cryogenic conditions, then use hole
The filter plant pressure filtration of 2 microns of diameter is restored to room temperature to get Tibetan medicine skin care compositions.
Embodiment 2
A kind of massage cream includes the component of following mass percentage：Tibetan medicine skin care compositions 10%, gathers dormant oil 35%
Dimethyl siloxane 5%, carbonic acid dioctyl ester 1%, ceteareth -25 1%, PEG/PPG-30/10 poly dimethyl silicon
Oxygen alkane 5%, cetostearyl alcohol 5%, cocoyl glucoside 0.1%, stereth -2 0.5%, hydrogenation Sweet Almond Oil 5%,
Polyisobutene 0.1%, PEG-7 trihydroxy methyl propyl cocounut oil ether 1%, stearyl alcohol 0.1%, sea-buckthorn (HIPPOPHAE
RHAMNOIDES) oil 3%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.1%, glycine betaine 5%, glycerine
20%, glucan 0.1%, water surplus.
The Tibetan medicine skin care compositions is prepared by the Tibetan medicine of following parts by weight：1 part of Rhizoma Acori Calami, 10 parts of safron, thorn
1 part of CedarLeaves, 10 parts of German tamarisk, 1 part of lanatechead saussurea herb with flower.
The preparation method of the Tibetan medicine skin care compositions is as follows：(1) it decocts：Weigh Rhizoma Acori Calami, safron, Chinese juniper leaf,
German tamarisk, lanatechead saussurea herb with flower mixing, dry, pulverize to 10 mesh, by mixing medicinal material merging copper pot, deionized water be added not have drug,
It is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will decoct
It boils mixing medicinal material to take out, is cooled to 35 DEG C, aspergillus is added, the additive amount of the aspergillus is to decoct mixing medicinal material weight
0.1%, it stirs evenly, seals；It ferments 5 days under the conditions of 20 DEG C, obtains fermentation medicinal material；(3) it extracts：It will fermentation medicinal material merging
It in copper pot, is added in the ethyl alcohol that volume fraction is 95%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:3；Using
The ultrasonication that frequency is 45kHZ 1 minute, then water-bath flows back 1 hour under conditions of 90 DEG C, 500 mesh filter-cloth filterings, point
It Shou Ji not filtrate and filter residue；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and merged；
To first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 2 DEG C of cryogenic conditions, then micro- with aperture 1
The filter plant pressure filtration of rice, is restored to room temperature to get Tibetan medicine skin care compositions.
Embodiment 3
A kind of massage cream includes the component of following mass percentage：Tibetan medicine skin care compositions 6%, gathers dormant oil 25%
Dimethyl siloxane 3%, carbonic acid dioctyl ester 5%, ceteareth -25 2%, PEG/PPG-30/10 poly dimethyl silicon
Oxygen alkane 3%, cocoyl glucoside 1.5%, stereth -2 1%, hydrogenation Sweet Almond Oil 2%, gathers cetostearyl alcohol 3%
Isobutene 3%, PEG-7 trihydroxy methyl propyl cocounut oil ether 0.5%, stearyl alcohol 1.5%, sea-buckthorn (HIPPOPHAE
RHAMNOIDES) oil 2%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.3%, glycine betaine 3%, sorb
Alcohol 15%, glucan 1.5%, water surplus.
The Tibetan medicine skin care compositions is prepared by the Tibetan medicine of following parts by weight：5 parts of Rhizoma Acori Calami, 4 parts of safron, thorn
6 parts of CedarLeaves, 7 parts of German tamarisk, 4 parts of lanatechead saussurea herb with flower.
The preparation method of the Tibetan medicine skin care compositions is as follows：(1) it decocts：Weigh Rhizoma Acori Calami, safron, Chinese juniper leaf,
German tamarisk, lanatechead saussurea herb with flower mixing, dry, pulverize to 50 mesh, by mixing medicinal material merging copper pot, deionized water be added not have drug,
It is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will decoct
It boils mixing medicinal material to take out, is cooled to 40 DEG C, aspergillus is added, the additive amount of the aspergillus is to decoct mixing medicinal material weight
0.05%, it stirs evenly, seals；It ferments 8 days under the conditions of 15 DEG C, obtains fermentation medicinal material；(3) it extracts：It will fermentation medicinal material merging
It in copper pot, is added in the ethyl alcohol that volume fraction is 70%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:5；Using
The ultrasonication that frequency is 40kHZ 5 minutes, then water-bath flows back 2 hours under conditions of 95 DEG C, 300 mesh filter-cloth filterings, point
It Shou Ji not filtrate and filter residue；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and merged；
To first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 4 DEG C of cryogenic conditions, then micro- with aperture 2
The filter plant pressure filtration of rice, is restored to room temperature to get Tibetan medicine skin care compositions.
Embodiment 4
A kind of massage cream includes the component of following mass percentage：Tibetan medicine skin care compositions 3%, gathers dormant oil 20%
Dimethyl siloxane 1-5%, carbonic acid dioctyl ester 2%, ceteareth -25 1.5%, the poly- diformazans of PEG/PPG-30/10
Radical siloxane 2.5%, cetostearyl alcohol 2%, cocoyl glucoside 0.5%, stereth -2 0.8%, hydrogenation dessert almond
Oil 4%, polyisobutene 2%, PEG-7 trihydroxy methyl propyl cocounut oil ether 0.8%, stearyl alcohol 1%, sea-buckthorn (HIPPOPHAE
RHAMNOIDES) oil 0.7%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.5%, glycine betaine 4%, 1,
3 butanediols 10%, glucan 1%, water surplus.
The Tibetan medicine skin care compositions is prepared by the Tibetan medicine of following parts by weight：7 parts of Rhizoma Acori Calami, 2 parts of safron, thorn
8 parts of CedarLeaves, 5 parts of German tamarisk, 6 parts of lanatechead saussurea herb with flower.
The preparation method of the Tibetan medicine skin care compositions is as follows：(1) it decocts：Weigh Rhizoma Acori Calami, safron, Chinese juniper leaf,
German tamarisk, lanatechead saussurea herb with flower mixing, dry, pulverize to 80 mesh, by mixing medicinal material merging copper pot, deionized water be added not have drug,
It is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will decoct
It boils mixing medicinal material to take out, is cooled to 35 DEG C, aspergillus is added, the additive amount of the aspergillus is to decoct mixing medicinal material weight
0.08%, it stirs evenly, seals；It ferments 6 days under the conditions of 14 DEG C, obtains fermentation medicinal material；(3) it extracts：It will fermentation medicinal material merging
It in copper pot, is added in the ethyl alcohol that volume fraction is 90%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:4；Using
The ultrasonication that frequency is 30kHZ 8 minutes, then water-bath flows back 2 hours under conditions of 93 DEG C, 400 mesh filter-cloth filterings, point
It Shou Ji not filtrate and filter residue；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and merged；
To first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 4 DEG C of cryogenic conditions, then micro- with aperture 2
The filter plant pressure filtration of rice, is restored to room temperature to get Tibetan medicine skin care compositions.
Embodiment 5
A kind of massage cream includes the component of following mass percentage：Tibetan medicine skin care compositions 8%, gathers dormant oil 30%
Dimethyl siloxane 1-5%, carbonic acid dioctyl ester 7%, ceteareth -25 2.5%, the poly- diformazans of PEG/PPG-30/10
Radical siloxane 2%, cetostearyl alcohol 4%, cocoyl glucoside 2.5%, stereth -2 1.6%, hydrogenation Sweet Almond Oil
2%, polyisobutene 4%, PEG-7 trihydroxy methyl propyl cocounut oil ether 0.2%, stearyl alcohol 2%, sea-buckthorn (HIPPOPHAE
RHAMNOIDES) oil 2%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.2%, glycine betaine 2%, glycerine
10%, 1,3 butanediols 5%, glucan 2.5%, water surplus.
The Tibetan medicine skin care compositions is prepared by the Tibetan medicine of following parts by weight：3 parts of Rhizoma Acori Calami, 6 parts of safron, thorn
4 parts of CedarLeaves, 8 parts of German tamarisk, 3 parts of lanatechead saussurea herb with flower.
The preparation method of the Tibetan medicine skin care compositions is as follows：(1) it decocts：Weigh Rhizoma Acori Calami, safron, Chinese juniper leaf,
German tamarisk, lanatechead saussurea herb with flower mixing, dry, pulverize to 60 mesh, by mixing medicinal material merging copper pot, deionized water be added not have drug,
It is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will decoct
It boils mixing medicinal material to take out, is cooled to 40 DEG C, aspergillus is added, the additive amount of the aspergillus is to decoct mixing medicinal material weight
0.03%, it stirs evenly, seals；It ferments 9 days under the conditions of 18 DEG C, obtains fermentation medicinal material；(3) it extracts：It will fermentation medicinal material merging
It in copper pot, is added in the ethyl alcohol that volume fraction is 80%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:6；Using
The ultrasonication that frequency is 35kHZ 3 minutes, then water-bath flows back 1 hour under conditions of 97 DEG C, 200 mesh filter-cloth filterings, point
It Shou Ji not filtrate and filter residue；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and merged；
To first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 3 DEG C of cryogenic conditions, then micro- with aperture 2
The filter plant pressure filtration of rice, is restored to room temperature to get Tibetan medicine skin care compositions.
Comparative example 1
The difference is that, comparative example 1 is not added with Rhizoma Acori Calami with embodiment 3.
Comparative example 2
The difference is that, comparative example 2 is not added with safron with embodiment 3.
Comparative example 3
The difference is that, comparative example 3 is not added with Chinese juniper leaf with embodiment 3.
Comparative example 4
The difference is that, comparative example 4 is not added with German tamarisk with embodiment 3.
Comparative example 5
The difference is that, comparative example 5 is not added with lanatechead saussurea herb with flower with embodiment 3.
Comparative example 6
With embodiment 3 the difference is that, in comparative example 6 Tibetan medicine skin care compositions by following parts by weight Tibetan medicine system
It is standby to form：0.9 part of Rhizoma Acori Calami, 11 parts of safron, 0.9 part of Chinese juniper leaf, 11 parts of German tamarisk, 0.9 part of lanatechead saussurea herb with flower.
Comparative example 7
With embodiment 3 the difference is that, in comparative example 7 Tibetan medicine skin care compositions by following parts by weight Tibetan medicine system
It is standby to form：11 parts of Rhizoma Acori Calami, 0.9 part of safron, 11 parts of Chinese juniper leaf, 0.9 part of German tamarisk, 11 parts of lanatechead saussurea herb with flower.
Massage cream made from above-described embodiment and comparative example continuously tries out 30 through the 100 of 20~50 years old personnel respectively
It, the effect of massage cream obtained in the various embodiments described above is evaluated in comparative analysis.Wherein, test event is skin elasticity, red
The improvement situation of spot, itch, fash, eczema etc., the results are shown in Table 1.
Table 1
The massage cream of above-described embodiment 1-5 and comparative example 1-7 do not find that irritation and allergy are existing during on probation
As.
As known from Table 1：Each product is bright to the improvement degree of skin elasticity, erythema, itch, fash, eczema etc. in embodiment
It is aobvious higher than the improvement degree of each product in comparative example；Show the present invention Tibetan medicine skin care compositions in Rhizoma Acori Calami, safron,
The effect of Chinese juniper leaf, German tamarisk, lanatechead saussurea herb with flower compound through specific prescription, be far longer than the simple before no prescription has collaboration
The effect of synergy.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention,
Therefore all contents without departing from technical solution of the present invention, according to the technical essence of the invention any letter made to the above embodiment
Single modification, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (9)
1. a kind of Tibetan medicine skin care compositions, which is characterized in that be prepared by the Tibetan medicine of following parts by weight：1-10 parts of Rhizoma Acori Calami,
1-10 parts of safron, 1-10 parts of Chinese juniper leaf, 1-10 parts of German tamarisk, 1-10 parts of lanatechead saussurea herb with flower.
2. Tibetan medicine skin care compositions according to claim 1, goes to be characterized in that, the Tibetan medicine skin care compositions is by following heavy
The Tibetan medicine of amount part is prepared：3-7 parts of Rhizoma Acori Calami, 2-6 parts of safron, 4-8 parts of Chinese juniper leaf, 5-8 parts of German tamarisk, lanatechead saussurea herb with flower 3-6
Part.
3. Tibetan medicine skin care compositions according to claim 1 or 2, which is characterized in that the Tibetan medicine skin care compositions
Preparation method is as follows：(1) it decocts：Rhizoma Acori Calami, safron, Chinese juniper leaf, German tamarisk, lanatechead saussurea herb with flower mixing are weighed, dry, pulverize, it will
It mixes in medicinal material merging copper pot, deionized water is added not have a drug, it is soaking, heat, boil to water and be all evaporated, medicine is boiled
It is ripe, boil it is soft, obtain decoct mixing medicinal material；(2) it ferments：Mixing medicinal material will be decocted to take out, 35-45 DEG C is cooled to, aspergillus is added, stirs
It mixes uniformly, sealing；It ferments 5-10 days under the conditions of 10-20 DEG C, obtains fermentation medicinal material；(3) it extracts：Fermentation medicinal material is placed in copper
It in pot, is added in the ethyl alcohol that volume fraction is 50-95%, uses frequency for 1-10 points of the ultrasonication of 25kHZ-45kHZ
Clock, then water-bath flows back 1-2 hours under conditions of 90-100 DEG C, 100-500 mesh filter-cloth filterings collect filtrate and filter residue respectively；
Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and merged；Obtain first extract；(4) it filters：
First extract is centrifuged, supernatant liquor is taken, is preserved 1-2 days under 2-5 DEG C of cryogenic conditions, then with aperture 1-2 microns of filter plant
Pressure filtration is restored to room temperature to get Tibetan medicine skin care compositions.
4. Tibetan medicine skin care compositions according to claim 3, which is characterized in that the grain size of crushing is in the step (1)
10-100 mesh.
5. Tibetan medicine skin care compositions according to claim 3, which is characterized in that in the step (2), the aspergillus
Additive amount is the 0.01-0.1% for decocting mixing medicinal material weight.
6. Tibetan medicine skin care compositions according to claim 3, which is characterized in that in the step (3), the fermentation medicinal material
Weight ratio with ethyl alcohol is 1:(3-7).
7. according to application of the claim 1-6 any one of them Tibetan medicine skin care compositions in preparing cosmetics, wherein described
Tibetan medicine skin care compositions dosage be final products weight 0.1-10wt%.
8. a kind of massage cream, which is characterized in that include the component of following mass percentage：Such as any one of claim 1-6 institutes
The Tibetan medicine skin care compositions 0.1-10% that states, dormant oil 15-35%, dimethyl silicone polymer 1-5%, carbonic acid dioctyl ester 1-10%,
- 25 1-3%, PEG/PPG-30/10 dimethyl silicone polymer 0.5-5% of ceteareth, cetostearyl alcohol 1-5%, coconut palm
Oil base glucoside 0.1-3%, -2 0.5-2% of stereth, hydrogenation Sweet Almond Oil 0.1-5%, polyisobutene 0.1-5%,
PEG-7 trihydroxy methyl propyl cocounut oil ethers 0.1-1%, stearyl alcohol 0.1-3%, sea-buckthorn (HIPPOPHAE RHAMNOIDES) oil 0.1-
3%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.1-0.6%, glycine betaine 0.1-5%, polyalcohol 5-
20%, glucan 0.1-3%, water surplus.
9. massage cream according to claim 8, which is characterized in that the polyalcohol is sorbierite, glycerine, 1,3 butanediols
At least one of.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113425654A (en) * | 2021-05-13 | 2021-09-24 | 桑德才让 | Tibetan medicine whitening cream and preparation method thereof |
| CN113440457A (en) * | 2020-03-27 | 2021-09-28 | 上海相宜本草化妆品股份有限公司 | Bletilla striata formula and preparation method thereof |
| CN113855614A (en) * | 2021-11-18 | 2021-12-31 | 浙江大学滨海产业技术研究院 | Sunscreen composition and preparation method and application thereof |
| CN114796058A (en) * | 2022-05-26 | 2022-07-29 | 广州蕴美化妆品有限公司 | Cosmetic composition effective in anti-allergy repair and preparation method thereof |
-
2018
- 2018-05-12 CN CN201810455339.9A patent/CN108542844A/en not_active Withdrawn
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113440457A (en) * | 2020-03-27 | 2021-09-28 | 上海相宜本草化妆品股份有限公司 | Bletilla striata formula and preparation method thereof |
| CN113425654A (en) * | 2021-05-13 | 2021-09-24 | 桑德才让 | Tibetan medicine whitening cream and preparation method thereof |
| CN113425654B (en) * | 2021-05-13 | 2022-06-03 | 桑德才让 | Tibetan medicine whitening cream and preparation method thereof |
| CN113855614A (en) * | 2021-11-18 | 2021-12-31 | 浙江大学滨海产业技术研究院 | Sunscreen composition and preparation method and application thereof |
| CN113855614B (en) * | 2021-11-18 | 2023-05-23 | 浙江大学滨海产业技术研究院 | Sun-screening composition and preparation method and application thereof |
| CN114796058A (en) * | 2022-05-26 | 2022-07-29 | 广州蕴美化妆品有限公司 | Cosmetic composition effective in anti-allergy repair and preparation method thereof |
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