CN108498722A - A kind of Chinese medicine composition and its preparation method and application for treating stone in urinary system - Google Patents
A kind of Chinese medicine composition and its preparation method and application for treating stone in urinary system Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compositions and its preparation method and application for treating stone in urinary system, including following traditional Chinese medicinal material raw materials：11~16 parts of Radix Astragali, 13~19 parts of Longtube Ground Ivy Herb, 8~14 parts of Prunella vulgaris, 7~14 parts of corn stigma, 7~12 parts of Asiatic plantain, 4~7 parts of Chinese cassia tree, 5~9 parts of Cortex Phellodendri, 4~8 parts of ural licorice root tip.The present invention treats the Chinese medicine composition of stone in urinary system, is simple to manufacture, the regeneration of have no toxic side effect, is quick, can effectively prevent calculus, the internal lithogenous condition of shape has not existed, and the probability of natural calculus just substantially reduces.Therefore, Chinese medicine of the present invention has row's stone, dissolve stone, anti-stone effect well, significant in efficacy.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, specially a kind of Chinese medicine composition for treating stone in urinary system and its
Preparation method and application.
Background technology
Urinary calculi is also known as urolithiasis, and lithangiuria is one of most common urological diseases.The urinary system of human body
System is made of kidney tubal bladder urethra, and kidney and ureter are according to human body central axes balanced configuration urine after kidney generation
It is discharged through tubal bladder urethra, the calculus present in this organ, referred to as stone in urinary system.
The symptom of lithangiuria difference due to the difference of the position of calculus.As pelvicstone and ureteralstone is often shown as
Waist or abdominal pain；Vesical calculus often shows as urination interruption and urodynamic；Urethral calculus shows as dysuria, in drop
Shape is dripped, occurs that uroflow is interrupted and there are apparent pain in the retention of urine, when urination sometimes.The method of common treatment lithangiuria has at present
External stone crushing therapy, doctor trained in Western medicine therapeutic method of surgery and Methods of TCM.External stone crushing is good to single calculus effect, but
It is unsatisfactory to Calculus therapeutic effect, and there is certain wound to human tissue organ, recurrence can not be solved
Problem；Doctor trained in Western medicine therapeutic method of surgery has wound big, costly, the shortcomings that easily recurrence.Also there are many Chinese patent drugs or herbal medicine at present
For treating urinary calculus, but effect is also all very undesirable.
Invention content
In order to solve the above technical problems, the present invention provides a kind of Chinese medicine composition that treating stone in urinary system and its preparation side
Method, the Chinese medicine composition are simple to manufacture, and toxic side effect is small, curative effect is good, with obvious effects, can effectively shorten the course of disease, significant in efficacy.
It is an object of the present invention to provide a kind of Chinese medicine compositions for treating stone in urinary system comprising Xia Shuzhong
Medicinal raw material：11~16 parts of Radix Astragali, 13~19 parts of Longtube Ground Ivy Herb, 8~14 parts of Prunella vulgaris, 7~14 parts of corn stigma, Asiatic plantain 7~12
Part, 4~7 parts of Chinese cassia tree, 5~9 parts of Cortex Phellodendri, 4~8 parts of ural licorice root tip.
Further, the traditional Chinese medicinal material raw materials of the Chinese medicine composition include：12~15 parts of Radix Astragali, Longtube Ground Ivy Herb 14~18
Part, 9~13 parts of Prunella vulgaris, 8~13 parts of corn stigma, 8~11 parts of Asiatic plantain, 5~6 parts of Chinese cassia tree, 6~8 parts of Cortex Phellodendri, ural licorice root tip 5~7
Part.
Further, the traditional Chinese medicinal material raw materials of the Chinese medicine composition include：14 parts of Radix Astragali, 15 parts of Longtube Ground Ivy Herb, Prunella vulgaris
11 parts, 11 parts of corn stigma, 10 parts of Asiatic plantain, 6 parts of Chinese cassia tree, 7 parts of Cortex Phellodendri, 6 parts of ural licorice root tip.
Another purpose according to the present invention provides the preparation method of the Chinese medicine composition of above-mentioned treatment stone in urinary system,
Its step includes：
S1 takes Radix Astragali, Longtube Ground Ivy Herb, Prunella vulgaris, corn stigma, Asiatic plantain, Chinese cassia tree, Cortex Phellodendri, the ural licorice root tip of above-mentioned parts by weight, adds
Water extracts；
Extracting solution in S1 is concentrated into a medicinal extract by S2；
S3, it is 55%~65% that ethyl alcohol to alcohol content concentration of volume percent is added in a medicinal extract, is stirred evenly, quiet
It sets, filters, filtrate is concentrated into the secondary medicinal extract of active ingredient；
Secondary medicinal extract is processed into granule by S4.
Further, in S1, the number of extracting in water is 3~4 times, is added is equivalent to 12~15 times of medicinal material total weight every time
Water, extraction time be 3.5~4.5 hours.
Further, in S2, when extracting solution is condensed into 85 DEG C relative density be 1.15~1.25 a medicinal extract.
Further, in S3, time of repose is not less than 12 hours.
Further, in S3, relative density is 1.15~1.25 when secondary medicinal extract is 65 DEG C secondary medicinal extract.
Further, in S4, when granule is made in secondary medicinal extract, as auxiliary material, the additive amount of sucrose is addition sucrose
20% or less.
Another purpose according to the present invention provides the application of the Chinese medicine composition of above-mentioned treatment stone in urinary system, application
In treatment kidney stone, ureteral calculi, vesical calculus or urethral calculus.
Hereinafter, slightly illustrating to the property etc. of the above-mentioned raw materials of the present invention：
Radix Astragali：Property it is sweet, tepor enters the spleen channel, is apt to invigoration spleen qi, rises and lifts middle-jiao yang, function of the spleen and stomach, to " middle gas is depressed, and spleen soil is weak, under clear gas
It falls into most easily "《Herbal justice》), again can qi-supplementing, blood-engendering, take the photograph blood, middle benefit gas is used for qi-blood deficiency syndrome except heat, Qi dysfunction in blood control disease, in
Burnt deficiency-cold symptoms, fever due to deficiency of vital energy disease.
Longtube Ground Ivy Herb：Acrid flavour, slight bitter, cold nature.Return liver, kidney, bladder warp.Dampness removing is treating stranguria, clearing heat and detoxicating, eliminating stasis to subdue swelling.With
In heat gonorrhea, urolithiasis, jaundice with damp-heat pathogen, sore, carbuncle and painful swelling, traumatic injury.
Prunella vulgaris：It is pungent, bitter, it trembles with fear.Return liver, gallbladder channel.Clearing heat-fire, improving eyesight, mass dissipating and swelling eliminating.
Corn stigma：It is sweet in flavor, light, it is mild-natured.Return bladder, liver, gallbladder channel.There is inducing diuresis to remove edema；The effect of clearing liver cholagogic.Main oedema,
Dribbling urination, jaundice, cholecystitis, gall stone, hypertension, diabetes, alactation.
Asiatic plantain：It is sweet in flavor, it is cold in nature.Have effects that diuresis, heat-clearing, improving eyesight, eliminating the phlegm.Cure mainly urinary obstruction, stranguria with turbid discharge, band
Under, hematuria, jaundice, oedema, hot dysentery, diarrhea, nosebleed epistaxis, red eye, swell pain, larynx numbness, cough, skin ulcer etc..
Chinese cassia tree：Complement sun, warming spleen and stomach, removing internal cold, promoting blood circulation.The Yang-function insufficiency of kidneyzang, cold weak pulse of limb are controlled, yang depletion is collapsed, and abdominal pain is let out
It rushes down, cold hernia run quickly globefish, waist and knee crymodynia, Amenorrhea abdominal mass, cloudy subcutaneous ulcer, streamer, and empty sun is floating more, heat in the upper and cold in the lower.
Cortex Phellodendri：Bitter, it is cold in nature.Kidney, bladder warp.There is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.For damp and hot
Rush down dysentery, jaundice, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence is preesed, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, and eczema is wet
Sore.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing yin and lessening fire.For fire excess from yin deficiency, night sweat hectic fever due to yin.
Ural licorice root tip：It is sweet, it trembles with fear.The thoughts of returning home, small intestine, bladder warp.Purging intense heat and detonicating, inducing diuresis for treating strangurtia.For heat gonorrhea, oliguresis is cloudy
Pain in stem, in the heart accumulated heat.
The beneficial effects of the invention are as follows：
The present invention treats the Chinese medicine composition of stone in urinary system, and Chinese medicine composition of the invention is simple to manufacture, nontoxic secondary work
With, regeneration that is quick, can effectively prevent calculus, the internal lithogenous condition of shape has not existed, the probability of natural calculus
Just substantially reduce.Therefore, Chinese medicine of the present invention has row's stone, dissolve stone, anti-stone effect well, significant in efficacy.
Specific implementation mode
Below in conjunction with the specific embodiment of the invention, technical scheme of the present invention is clearly and completely described, is shown
So, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the reality in the present invention
Example is applied, every other embodiment obtained by those of ordinary skill in the art without making creative efforts all belongs to
In the scope of protection of the invention.
Embodiment 1
The preparation of Chinese medicinal composition granules：
Raw material includes：11 parts of Radix Astragali, 13 parts of Longtube Ground Ivy Herb, 8 parts of Prunella vulgaris, 7 parts of corn stigma, 7 parts of Asiatic plantain, 4 parts of Chinese cassia tree, Huang
5 parts of cypress, 4 parts of ural licorice root tip；
Preparation method：Take 11 parts of Radix Astragali, 13 parts of Longtube Ground Ivy Herb, 8 parts of Prunella vulgaris, 7 parts of corn stigma, 7 parts of Asiatic plantain, 4 parts of Chinese cassia tree,
The water for being equivalent to 12 times of medicinal material total weight is added in 5 parts of Cortex Phellodendri, 4 parts of ural licorice root tip, extracts 3.5 hours, extracts 3 times；3 times are extracted
Extracting solution mixing, when being condensed into 85 DEG C relative density be 1.15~1.25 a medicinal extract；Ethyl alcohol is added extremely in medicinal extract
Alcohol content concentration of volume percent is 55%, is stirred evenly, and stands 12 hours, filtration, relative density when filtrate is concentrated into 65 DEG C
For 1.15~1.25 secondary medicinal extract；Sucrose will be added in secondary medicinal extract, is processed into granule, the additive amount of sucrose is 15%.
Embodiment 2
The preparation of Chinese medicinal composition granules：
Raw material includes：14 parts of Radix Astragali, 15 parts of Longtube Ground Ivy Herb, 11 parts of Prunella vulgaris, 11 parts of corn stigma, 10 parts of Asiatic plantain, Chinese cassia tree 6
Part, 7 parts of Cortex Phellodendri, 6 parts of ural licorice root tip；
Preparation method：14 parts of Radix Astragali, 15 parts of Longtube Ground Ivy Herb, 11 parts of Prunella vulgaris, 11 parts of corn stigma, 10 parts of Asiatic plantain, Chinese cassia tree 6
The water for being equivalent to 15 times of medicinal material total weight is added in part, 7 parts of Cortex Phellodendri, 6 parts of ural licorice root tip, extracts 4.5 hours, extracts 4 times；4 times are carried
The extracting solution mixing taken, the medicinal extract that relative density is 1.15~1.25 when being condensed into 85 DEG C；Ethyl alcohol is added in medicinal extract
It is 65% to alcohol content concentration of volume percent, stirs evenly, stand 18 hours, filtration, filtrate is concentrated into relatively close at 65 DEG C
The secondary medicinal extract that degree is 1.15~1.25；Sucrose will be added in secondary medicinal extract, be processed into granule, the additive amount of sucrose is
20%.
Embodiment 3
The preparation of Chinese medicinal composition granules：
Raw material includes：16 parts of Radix Astragali, 19 parts of Longtube Ground Ivy Herb, 4 parts of Prunella vulgaris, 14 parts of corn stigma, 12 parts of Asiatic plantain, 7 parts of Chinese cassia tree,
9 parts of Cortex Phellodendri, 8 parts of ural licorice root tip；
Preparation method：16 parts of Radix Astragali, 19 parts of Longtube Ground Ivy Herb, 4 parts of Prunella vulgaris, 14 parts of corn stigma, 12 parts of Asiatic plantain, 7 parts of Chinese cassia tree,
The water for being equivalent to 13 times of medicinal material total weight is added in 9 parts of Cortex Phellodendri, 8 parts of ural licorice root tip, extracts 4 hours, extracts 4 times；4 times are extracted
Extracting solution mixes, the medicinal extract that relative density is 1.15~1.25 when being condensed into 85 DEG C；Ethyl alcohol is added in medicinal extract to containing
Alcohol amount concentration of volume percent is 60%, is stirred evenly, and stands 24 hours, and filtration, relative density is when filtrate is concentrated into 65 DEG C
1.15~1.25 secondary medicinal extract；Sucrose will be added in secondary medicinal extract, is processed into granule, the additive amount of sucrose is 18%.
Embodiment 4
The instructions of taking of the Chinese medicine composition of above-mentioned treatment stone in urinary system is：Each taking 15 grams, three times per day, before meals
It takes within 30 minutes, light salt brine takes, and cool, peppery food should not be eaten in drug administration process, and pregnant woman prohibits clothes, there is digestive tract ulcer disease trouble
The careful clothes of person.
The present invention treats the Chinese medicine composition of stone in urinary system through clinical treatment, significant in efficacy, by course for the treatment of medication, can not answer
Hair.Here is the clinical test that treatment urolithiasis Chinese medicine using the present invention carries out, and case treatment results are as follows：
1, week certain, man, 25 years old, abdominal pain two days on the right side of patient.Right side ureteral calculi, double kidney microliths.By taking this
The treatment recovery from illness in two months of invention Chinese medicine.Double kidneys, double ureter, bladder no abnormality seen.
2, Zhao so-and-so, female, 35 years old, abdominal pain 3 days on the right side of patient.Right side ureteral calculi.Take Chinese medicine of the present invention two months
It, double kidneys, double ureter, bladder no abnormality seen.Conclusion：Right ureter calculus is cured.
3, Mr. Wang, male 26 years old, once goes multiple lithotripsy in treatment, but lithagogue effect is very poor.Also a variety of Chinese patent drugs were once taken, were controlled
It treats equal effect and owes good.Through taking three months days of Chinese medicine of the present invention, start that the calculus that more than ten block sizes do not wait is discharged, clinical symptoms disappear
It loses.
4, Wu so-and-so, female, 34 years old, once go multiple lithotripsy in treatment, after treatment the several months recur again.Once a variety of Chinese patent drugs were taken,
Therapeutic effect is bad.Take Chinese medicine of the present invention three months, patient's self-induction calculus symptom disappears, and body gradually restores.
5, Yin so-and-so, man, 42 years old, abdominal pain on the left of patient, urine band blood sometimes.Left side ureter lower end calculus.Take this
Invention Chinese medicine one month is simultaneously checked, and double kidneys, double ureter, bladder are without exception.Conclusion：Left ureter calculus is cured.
6, marquis, female, 46 years old, patient's calculus medical history more than 3 years, during which once line number time lithotripsy in treatment.Also a variety of grass were taken
Medicine and Chinese patent drug, treatment are ineffective.Once capable multiple lithotripsy in treatment, but lithagogue effect is very poor.Take three, Chinese medicine of the present invention
Month, left kidney is normal.Symptom is substantially reduced, can participate in daily labour.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (10)
1. a kind of Chinese medicine composition for treating stone in urinary system, which is characterized in that including following traditional Chinese medicinal material raw materials：Radix Astragali 11~16
Part, 13~19 parts of Longtube Ground Ivy Herb, 8~14 parts of Prunella vulgaris, 7~14 parts of corn stigma, 7~12 parts of Asiatic plantain, 4~7 parts of Chinese cassia tree, Cortex Phellodendri 5
~9 parts, 4~8 parts of ural licorice root tip.
2. a kind of Chinese medicine composition for treating stone in urinary system according to claim 1, which is characterized in that the Chinese medicine
The traditional Chinese medicinal material raw materials of composition include：12~15 parts of Radix Astragali, 14~18 parts of Longtube Ground Ivy Herb, 9~13 parts of Prunella vulgaris, corn stigma 8~13
Part, 8~11 parts of Asiatic plantain, 5~6 parts of Chinese cassia tree, 6~8 parts of Cortex Phellodendri, 5~7 parts of ural licorice root tip.
3. a kind of Chinese medicine composition for treating stone in urinary system according to claim 1, which is characterized in that the Chinese medicine
The traditional Chinese medicinal material raw materials of composition include：14 parts of Radix Astragali, 15 parts of Longtube Ground Ivy Herb, 11 parts of Prunella vulgaris, 11 parts of corn stigma, 10 parts of Asiatic plantain,
6 parts of Chinese cassia tree, 7 parts of Cortex Phellodendri, 6 parts of ural licorice root tip.
4. special according to a kind of preparation method of any Chinese medicine compositions that treating stone in urinary system of claim 1-3
Sign is that step includes：
S1 takes Radix Astragali, Longtube Ground Ivy Herb, Prunella vulgaris, corn stigma, Asiatic plantain, Chinese cassia tree, Cortex Phellodendri, the ural licorice root tip of above-mentioned parts by weight, water is added to carry
It takes；
Extracting solution in S1 is concentrated into a medicinal extract by S2；
S3, it is 55%~65% that ethyl alcohol to alcohol content concentration of volume percent is added in a medicinal extract, is stirred evenly, and is stood, filter
It crosses, filtrate is concentrated into the secondary medicinal extract of active ingredient；
Secondary medicinal extract is processed into bead dosage form or capsule formulation by S4.
5. a kind of preparation method of Chinese medicine composition for treating stone in urinary system according to claim 4, which is characterized in that
In S1, the number of extracting in water is 3~4 times, and each that the water for being equivalent to 12~15 times of medicinal material total weight is added, extraction time is
3.5~4.5 hours.
6. a kind of preparation method of Chinese medicine composition for treating stone in urinary system according to claim 4, which is characterized in that
In S2, when extracting solution is condensed into 85 DEG C relative density be 1.15~1.25 a medicinal extract.
7. a kind of preparation method of Chinese medicine composition for treating stone in urinary system according to claim 4, which is characterized in that
In S3, time of repose is not less than 12 hours.
8. a kind of preparation method of Chinese medicine composition for treating stone in urinary system according to claim 4, which is characterized in that
In S3, relative density is 1.15~1.25 when secondary medicinal extract is 65 DEG C secondary medicinal extract.
9. a kind of preparation method of Chinese medicine composition for treating stone in urinary system according to claim 4, which is characterized in that
In S4, when granule is made in secondary medicinal extract, for addition sucrose as auxiliary material, the additive amount of sucrose is 20% or less.
10. according to a kind of any Chinese medicine composition applications that treating stone in urinary system of claim 1-3, feature exists
In the Chinese medicine composition is applied to treatment kidney stone, ureteral calculi, vesical calculus or urethral calculus.
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| CN201710990184.4A CN108498722A (en) | 2017-10-23 | 2017-10-23 | A kind of Chinese medicine composition and its preparation method and application for treating stone in urinary system |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1200895A (en) * | 1997-05-29 | 1998-12-09 | 杨学忠 | Multi-function plant health-care drink |
| CN101618110A (en) * | 2008-07-03 | 2010-01-06 | 北京以岭药业有限公司 | Application of Chinese medicinal composition in preparing medicament for treating urinary calculi |
| CN103251684A (en) * | 2013-06-09 | 2013-08-21 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
-
2017
- 2017-10-23 CN CN201710990184.4A patent/CN108498722A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1200895A (en) * | 1997-05-29 | 1998-12-09 | 杨学忠 | Multi-function plant health-care drink |
| CN101618110A (en) * | 2008-07-03 | 2010-01-06 | 北京以岭药业有限公司 | Application of Chinese medicinal composition in preparing medicament for treating urinary calculi |
| CN103251684A (en) * | 2013-06-09 | 2013-08-21 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
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