CN108143967A - A kind of capsule medicine and preparation method for treating gout - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating gout according to the understanding mechanism of Chinese traditional treatment gout, each component and mass parts ratio of the drug are as follows：30~100g of edible tulip, 250~550g of smilax, 100~350g of coix seed, 80~160g of the root of Dahurain angelica, 250~550g of Chinese violet, 50~160g of Rhizoma Atractylodis Macrocephalae, 150~550g of dandelion, 100~260g of wild chrysanthemum, 100~350g of caulis lonicerae, 50~120g of Fructus Liquidambaris, 100~350g of Asiatic plantain, 60~120g of the root of Chinese clematis, 60~150g of moutan bark, 30~100g of Radix Notoginseng, 60~150g of lily, 50~120g of safflower；Drug provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine and preparation method for treating gout

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating gout, particularly for gout The capsule medicine and the field of preparation method that patient uses.

Background technology

It is shown according to documents and materials：Gout is metabolic disease caused by purine metabolic disturbance causes uric acid synthesis to increase. During renal dysfunction, since the uric acid clearance decline of kidney can also cause uric acid level to rise.Uric acid in blood plasma reaches full With cause monosodium urate crystallization deposition around the distal joint with respect in the tissue for lacking blood vessel.The appearance of this crystallization can be led The acute inflammation synovitis of simple joint or multi-joint is caused, gout is more common in male, and big toe is most common afflicted area Domain, 50%~70% first attack are that this.90% patient with gout can occur first in its some period in life Articulationes metatarsophalangeae is involved.Other foot areas that may be involved have dorsal portion, heel and ankle.Other than involving joint, urine Acid crystal can also be deposited on subcutaneously, referred to as tophus.

At present, the method that gout there is no radical cure is clinically mostly used steroidal anti-inflammatory drugs, glucocorticoid, allopurinol, autumn Tazettine etc., this similar drug energy rapid pain relief.But it also suffers from certain drawbacks, palliative, side effect is big, long-term to take With also there is larger damage to the gastrointestinal tract of human body, hepatic and renal function.

So, a kind of Chinese medicine composition that can effectively treat gout how is just found, is that those skilled in the art urgently will It solves the problems, such as.

Invention content

With the continuous development of China's traditional Chinese medicine, in treatment gout, people gradually appreciate Chinese traditional treatment pain The advantages of wind, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gout Present situation, the purpose of the invention is to provide a kind of capsule medicines for treating gout, restore strong early to solve patient with gout The problem of health.The drug is using common Chinese medicine as raw material, by selecting rational drug and mass parts ratio, can effectively be treated State gout.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：A kind of capsule for treating gout is provided Agent drug and preparation method, which is characterized in that each component and mass parts of the drug are than as follows：

30~100g of edible tulip, 250~550g of smilax, 100~350g of coix seed, 80~160g of the root of Dahurain angelica, Chinese violet 250~ 550g, 50~160g of Rhizoma Atractylodis Macrocephalae, 150~550g of dandelion, 100~260g of wild chrysanthemum, 100~350g of caulis lonicerae, Fructus Liquidambaris 50~ 120g, 100~350g of Asiatic plantain, 60~120g of the root of Chinese clematis, 60~150g of moutan bark, 30~100g of Radix Notoginseng, 60~150g of lily, 50~120g of safflower.

A kind of capsule medicine and preparation method for treating gout, which is characterized in that each component and matter of the drug Part is measured than as follows：

36~90g of edible tulip, 280~480g of smilax, 115~310g of coix seed, 90~140g of the root of Dahurain angelica, 280~480g of Chinese violet, 56~140g of Rhizoma Atractylodis Macrocephalae, 180~480g of dandelion, 115~230g of wild chrysanthemum, 115~310g of caulis lonicerae, 56~105g of Fructus Liquidambaris, 115~320g of Asiatic plantain, 70~105g of the root of Chinese clematis, 70~130g of moutan bark, 36~90g of Radix Notoginseng, 70~130g of lily, safflower 56 ~105g.

A kind of capsule medicine and preparation method for treating gout, which is characterized in that each component and matter of the drug Part is measured than as follows：

Edible tulip 80g, smilax 420g, coix seed 280g, root of Dahurain angelica 120g, Chinese violet 420g, Rhizoma Atractylodis Macrocephalae 120g, dandelion 420g, open country Chrysanthemum 200g, caulis lonicerae 280g, Fructus Liquidambaris 95g, Asiatic plantain 280g, root of Chinese clematis 95g, moutan bark 116g, Radix Notoginseng 80g, lily 118g, safflower 95g.

A kind of capsule medicine and preparation method for treating gout, which is characterized in that system that described method includes following steps It is standby to form：

A, it after above-mentioned raw materials Chinese medicine being picked impurity and dust, is ground into according to mass parts than altogether（30~50 mesh）Graininess packet It decocts；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 45min, then soaked drug is put into marmite again, The cold boiling water for adding in 7~9 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning 120min, leaching liquid；2. the cold boiling water for adding in 6~8 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time It boils, when decocting to 15min, turns slow boiling tanning 110min, leaching liquid；3. the mixing of secondary liquid is condensed into relative density is 1.08 clear cream, it is then dry, grind with it is after disinfection to reserve；

C, the method for 1. preparing Chinese medicine capsules according to tradition after smalls sieving ground in B, adds in suitable micro mist silicon Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule（Its capsule it is sealed after total length be 23.3mm, medicinal powder Capacity 0.4~0.5g/）, 2. then polish, sterilize, sealed packaging.

A kind of capsule medicine and preparation method for treating gout, which is characterized in that the instructions of taking is：It will prepare Capsule medicine three times a day to take, once a dose in the morning, afternoon and evening, dosage 2.5g (5)/time, half an hour warm water after meal It takes.（Quit smoking, wine, raw green onion, raw garlic, pungent irritable food）.30 days as a treatment course after treating 3~7 courses for the treatment of, check： Blood uric acid is down to normal range (NR), and clinical symptoms and sign disappear, and obtain interim recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine It records.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Edible tulip, nature and flavor：It is sweet, micro-pungent, cool, there is the effect of clearing heat and detoxicating, reducing phlegm and resolving masses, for treating carbuncle swells serious case of furuncle, scrofula Subcutaneous nodule, snakebite and bugbite, lame lump in the abdomen lump in the abdomen；

Smilax, nature and flavor：It is sweet light, flat, there is the effect of removing toxic substances, dehumidifying, sharp joint, for treating syphilis, stranguria with turbid discharge, muscles and bones contraction Bitterly, the diseases such as tinea pedis, furunculosis, carbuncle swells, scrofula；

Coix seed, nature and flavor：It is sweet, light, be slightly cold, have dampness removing invigorating the spleen, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus the effect of, for treat oedema, Under tinea pedis, dribbling urination, damp-warm diseases, diarrhea band, the diseases such as arthralgia pain due to rheumatism, muscle arteries and veins contraction, lung carbuncle, acute appendicitis, flat wart；

The root of Dahurain angelica, nature and flavor：Warm-natured, acrid flavour, gas fragrance, slight bitter, have the effect of wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving, for controlling Treat headache, toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus；

Chinese violet, nature and flavor：It is bitter, cold, have clearing heat and promoting diuresis, the efficacy of removing toxicity for detumescence imitate, for treat furunculosis, carbuncle swells, scrofula, jaundice, The diseases such as dysentery, diarrhea, hot eyes, larynx numbness, venomous snake bite；

Rhizoma Atractylodis Macrocephalae, nature and flavor：It is bitter, sweet, warm, there is the effect of air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating Spleen-Qi Deficiency The diseases such as weak, anorexia and loose stool, phlegm and retained fluid oedema, exterior deficiency spontaneous perspiration, fetal irritability；

Dandelion, nature and flavor：Sweet, slight bitter is trembled with fear, and has the effect of clearing heat and detoxicating, carbuncle that disappears dissipating bind, swollen for treatmentization heat toxin, the evil that disappears Tuberculosis, dissipates the diseases such as stagnant gas at Detoxicating food-poisoning；

Wild chrysanthemum, nature and flavor：Be slightly cold, be pungent, is bitter, have wind and heat dispersing, subdhing swelling and detoxicating the effect of, for treat anemopyretic cold, pneumonia, The diseases such as diphtheria, gastroenteritis, hypertension, malignant boil, carbuncle, aphtha, erysipelas, eczema, epidemic blisters；

Caulis lonicerae, nature and flavor：It is sweet, cold, there is the effect of clearing heat and detoxicating, dispelling wind dredging collateral, for treat warm disease heating, toxic-heat and blood stasis, Carbuncle swells sore, beriberoid pyretic arthralgia, redness and swelling of joints heat pain；

Fructus Liquidambaris, nature and flavor：It is bitter, mild-natured, have dispelling, collateral-activating, Li Shui, promoting menstruation the effect of, for treating joint pain, fiber crops Wooden spasm, oedema turgor, breast less, the diseases such as Amenorrhea；

Asiatic plantain, nature and flavor：It is sweet in flavor, cold in nature, there is the effect of heat-clearing, diuresis, eliminating the phlegm, cool blood, removing toxic substances, for treating oedema urine Less, puckery pain of heat gonorrhea, summer-heat and damp rush down dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus；

The root of Chinese clematis, nature and flavor：It is acrid flavour, salty, warm-natured, have wind-damp dispelling, degrading the channel the effect of, for treating arthralgia pain due to rheumatism, limbs Numbness, muscle arteries and veins contraction, joint stuffiness；

Moutan bark, nature and flavor：It is bitter, pungent, be slightly cold, have clearing heat and cooling blood, it is promoting blood circulation and removing blood stasis the effect of, enter ying blood, epidemic heat syndrome for treating heat Send out spot, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to yin, closed dysmenorrhea, the pain of injury caused by falling and tumbling, carbuncle sore tumefacting virus；

Radix Notoginseng, nature and flavor：Sweet, slight bitter, temperature, have dissipate stasis of blood hemostasis, detumescence ding-tong the effect of, for treat spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, It has blood in stool, the diseases such as uterine bleeding, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling；

Lily, nature and flavor：It is sweet in flavor, cold in nature, there is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, for treating deficiency of Yin cough caused by dryness, overstrain cough cough It is blood, dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance abdominal pain, born of the same parents' numbness is pained, and a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula.

Drug of the present invention is the principle based on Chinese traditional treatment gout, is recognized from the pathomechanism according to gout and pharmacological action For：With regard to gout, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned gout, the drug prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating gout, which is characterized in that each component and mass parts of the drug are than as follows：

Edible tulip 80g, smilax 420g, coix seed 280g, root of Dahurain angelica 120g, Chinese violet 420g, Rhizoma Atractylodis Macrocephalae 120g, dandelion 420g, open country Chrysanthemum 200g, caulis lonicerae 280g, Fructus Liquidambaris 95g, Asiatic plantain 280g, root of Chinese clematis 95g, moutan bark 116g, Radix Notoginseng 80g, lily 118g, safflower 95g.

Embodiment 2：

A kind of capsule medicine for treating gout, which is characterized in that each component and mass parts of the drug are than as follows：

Edible tulip 90g, smilax 480g, coix seed 310g, root of Dahurain angelica 140g, Chinese violet 480g, Rhizoma Atractylodis Macrocephalae 140g, dandelion 480g, open country Chrysanthemum 230g, caulis lonicerae 310g, Fructus Liquidambaris 105g, Asiatic plantain 320g, root of Chinese clematis 105g, moutan bark 130g, Radix Notoginseng 90g, lily 130g, safflower 105g.

Embodiment 3：

A kind of capsule medicine for treating gout, which is characterized in that each component and mass parts of the drug are than as follows：

Edible tulip 100g, smilax 550g, coix seed 350g, root of Dahurain angelica 160g, Chinese violet 550g, Rhizoma Atractylodis Macrocephalae 160g, dandelion 550g, open country Chrysanthemum 260g, caulis lonicerae 350g, Fructus Liquidambaris 120g, Asiatic plantain 350g, root of Chinese clematis 120g, moutan bark 150g, Radix Notoginseng 100g, lily 150g, safflower 120g.

Model case：

Through clinical conditions patient with gout totally 1670, the age is 1050 of 51 years old or more, only 620 for 51 years old with Under.In 1670 patients disease obtain fully recover temporarily have 1005, effective 565, invalid 100.Total effective rate is up to 94%.

Claims (3)

1. a kind of capsule medicine for treating gout, which is characterized in that each component and mass parts of the drug are than following institute Show：

30~100g of edible tulip, 250~550g of smilax, 100~350g of coix seed, 80~160g of the root of Dahurain angelica, Chinese violet 250~ 550g, 50~160g of Rhizoma Atractylodis Macrocephalae, 150~550g of dandelion, 100~260g of wild chrysanthemum, 100~350g of caulis lonicerae, Fructus Liquidambaris 50~ 120g, 100~350g of Asiatic plantain, 60~120g of the root of Chinese clematis, 60~150g of moutan bark, 30~100g of Radix Notoginseng, 60~150g of lily, 50~120g of safflower.

2. it is according to claim 1 treatment gout capsule medicine, which is characterized in that each component of the drug and Mass parts are than as follows：

36~90g of edible tulip, 280~480g of smilax, 115~310g of coix seed, 90~140g of the root of Dahurain angelica, 280~480g of Chinese violet, 56~140g of Rhizoma Atractylodis Macrocephalae, 180~480g of dandelion, 115~230g of wild chrysanthemum, 115~310g of caulis lonicerae, 56~105g of Fructus Liquidambaris, 115~320g of Asiatic plantain, 70~105g of the root of Chinese clematis, 70~130g of moutan bark, 36~90g of Radix Notoginseng, 70~130g of lily, safflower 56 ~105g.

3. the capsule medicine of the treatment gout according to claim 1 to 2, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Edible tulip 80g, smilax 420g, coix seed 280g, root of Dahurain angelica 120g, Chinese violet 420g, Rhizoma Atractylodis Macrocephalae 120g, dandelion 420g, open country Chrysanthemum 200g, caulis lonicerae 280g, Fructus Liquidambaris 95g, Asiatic plantain 280g, root of Chinese clematis 95g, moutan bark 116g, Radix Notoginseng 80g, lily 118g, safflower 95g.