CN104740375A - Traditional Chinese medicine preparation for treating thromboangiitis obliterans - Google Patents

Traditional Chinese medicine preparation for treating thromboangiitis obliterans Download PDF

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Publication number
CN104740375A
CN104740375A CN201510078262.4A CN201510078262A CN104740375A CN 104740375 A CN104740375 A CN 104740375A CN 201510078262 A CN201510078262 A CN 201510078262A CN 104740375 A CN104740375 A CN 104740375A
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chinese medicine
medicine preparation
traditional chinese
thromboangiitis obliterans
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CN201510078262.4A
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高成
孙吉峰
张志华
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Qingdao Central Hospital
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Qingdao Central Hospital
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Abstract

The invention relates to a traditional Chinese medicine preparation, in particular relates to a traditional Chinese medicine preparation for treating thromboangiitis obliterans. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 3-5 parts of fruit of keiske wormwood, 3-5 parts of lalang grass rhizome, 5-10 parts of kadsura root-bark, 5-10 parts of aleuritopteris argentea, 5-10 parts of reed flowers, 10-15 parts of flos carthami, 10-15 parts of Desmos cochinchinensis Lour., 10-15 parts of sinapis alba, 10-15 parts of myrica nana bark, 15-20 parts of fruits of aucuba himalaica var.dolichophylla,15-20 parts of lamiophlomis rotate, 15-20 parts of blumea hongkongensis, 15-20 parts of siberian walking fern, 15-20 parts of silkworm excrement and 15-20 parts of red peony root. The traditional Chinese medicine preparation is safe and reliable, has the efficacies of tonifying qi, nourishing blood, expelling cold dampness addiction, activating blood circulation, removing stasis, removing the necrotic tissue and promoting granulation, has a unique treatment effect on various symptoms of vasculitis, and is high in recovery rate.

Description

A kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans.
Background technology
Thromboangiitis obliterans is in a kind of rare chronic recurrent, the segmental diseases associated with inflammation of small artery and vein, and lower limb are common.Show as suffering limb ischemia, pain, intermittent claudication, pulsation of foot dorsal artery weaken or disappear and migrans Superficial phlebitis, severe patient has acra ulcer and necrosis.
Primary disease is more common in person between twenty and fifty, is apt to occur in lower limb.Suffering limb presents momentary or persistence is pale, cyanosis, have scorching hot and twinge, and when sick limb is sagging, color of the leather reddens, and bleaches during upper act, and then toes are numb, and Calf muscle pain, excites during walking, disappears during rest; Often there is superficial phlebitis and edema in calf.Find during inspection that pulsation of foot dorsal artery weakens or disappears.Along with PD can occur intermittent claudication and Raynaud phenomenon, night pain.
At present, treatment thromboangiitis obliterans mainly long-term steroid antibiotic etc or operation is treated, although all drug short run effects are obvious, long-term efficacy is imprecise, and price costly.In addition, although the operation method of thromboangiitis obliterans is more, because pathological changes involves arteriolar more, surgical effect owes desirable, is difficult to radical cure.Therefore, according to the principle of the traditional Chinese medical science " treating both the principal and secondary aspects of a disease ", need badly and invent a kind of Chinese medicine to the ill to treat, reach the shortening course of disease, prevent the object that chronic disease recurs.
Thromboangiitis obliterans mainly invades limbs, from the Chinese point of view: the reason of primary disease is invasion cold-damp, and pyretic toxicity inside fire attack, battalion defends imbalance, malnutrition, and vigour is poor, and clear sun can not walk logical extremity, coagulation of QI-blood, caused by meridians obstruct is obstructed.Again because primary disease and cigarette (nicotine) drinks, medicine, wound are cold, spirit, endocrine disturbance are relevant, and vasculitic pathological change is that blood vessel produces spasm and causes angiodystrophia, vascellum tunica interna incrassation, muddy, finally cause blood to fasten formation, lumen of vessels is inaccessible, its symptom, and suffering limb is ice-cold, acid account, redness, shortness of breath and fatigue, cardiopalmus, dizzy, spirit is burnt tired; red urine; constipation due to dry stool, amyotrophy, toes variable color; water of suppurating during twinge; corrupt, wound is not healed, serious local necrosis; general malaise, causes amputation to disable.
Its disease of thromboangiitis obliterans a kind of dislikes cellulitis disease, and this patient is agonizing, has a delicate constitution, how because malpractice develops complications death.The Chinese medicine and western medicine of current treatment thromboangiitis obliterans is more, but it is comparatively slow to there is curative effect, need the regular hour, or therapeutic effect is not good, and is difficult to the defect of radical cure.
Summary of the invention
According to the deficiencies in the prior art, try hard to, from the angle of health care, disclose a kind for the treatment of rapid-action, effective, the Chinese medicine preparation of the treatment thromboangiitis obliterans that cure rate is high.
A kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans of the present invention, according to weight parts, prepared by following raw material of Chinese medicine: ANLV 3 ~ 5 parts, Rhizoma Imperatae 3 ~ 5 parts, Cortex cercis chinensis 5 ~ 10 parts, Aleuritopteris argentea (Gmel.) Fee 5 ~ 10 parts, 5 ~ 10 parts, awns, 10 ~ 15 parts, Flos Carthami, curled paralysis 10 ~ 15 parts, Semen Sinapis Albae 10 ~ 15 parts, Cortex myricae nanae radicis skin 10 ~ 15 parts, the Corallium Japonicum Kishinouye that comes into leaves really 15 ~ 20 parts, Radix Lamiophlomidis Rotatae 15 ~ 20 parts, Radix Buddlejae Butterflybush 15 ~ 20 parts, Herba Camptosori Sibirici 15 ~ 20 parts, Bombyx mori L. 15 ~ 20 parts, Radix Paeoniae Rubra 15 ~ 20 parts.
Wherein, preferred version is as follows:
According to weight parts, formulated by following raw material of Chinese medicine: really 18 parts, ANLV 4 parts, Rhizoma Imperatae 4 parts, Cortex cercis chinensis 8 parts, Aleuritopteris argentea (Gmel.) Fee 8 parts, 8 parts, awns, 12 parts, Flos Carthami, curled paralysis 12 parts, Semen Sinapis Albae 12 parts, Cortex myricae nanae radicis skin 12 parts, the Corallium Japonicum Kishinouye that comes into leaves, Radix Lamiophlomidis Rotatae 18 parts, Radix Buddlejae Butterflybush 18 parts, Herba Camptosori Sibirici 18 parts, Bombyx mori L. 18 parts, Radix Paeoniae Rubra 18 parts.
The preparation method of the Chinese medicine preparation for the treatment of thromboangiitis obliterans of the present invention, prepare in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Each 200 ~ 300ml, 3 times on the one.
Pharmacology analysis:
ANLV: toil, temperature.Enter meridian of Foot-JUE YIN.Main the five internal organs blood stasis, aqueous vapor in abdomen, sets out and swollenly stays heat.Anemofrigid-damp arthralgia, all pains of health.Clots absorbing, damp eliminating.Control women's blood stasis amenorrhea, stop the stasis of blood stomachache puerperal, traumatic injury, rheumatic arthralgia.
Rhizoma Imperatae: sweet, cold.Enter lung, stomach, small intestine meridian.Main impairment caused by overstrain void is won, invigorating the spleen and replenishing QI, except blood stasis, blood close cold and heat, and diuresis.Removing heat from blood, hemostasis, heat clearing away, diuresis.Control calentura excessive thirst, spit blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.
Cortex cercis chinensis: bitter in the mouth is flat, nontoxic.Enter liver, spleen two warp.Promoting blood circulation to restore menstrual flow, subduing swelling and detoxicating.Control anemofrigid-damp arthralgia, women's amenorrhea, vim and vigour pain, sore throat, drench disease, carbuncle, tinea scabies, traumatic injury, snake bite and insect sting.
Aleuritopteris argentea (Gmel.) Fee: pungent; Sweet; Flat.Return lung; Liver Channel.Expelling phlegm for arresting cough; Promoting blood circulation to restore menstrual flow; Dampness removing; Removing toxic substances and promoting subsidence of swelling.Main cough; Menoxenia; Amenorrhea is suffered from abdominal pain; Leucorrhea with red and white discharge; Pulmonary tuberculosis hemoptysis; Loose stool and diarrhea; Difficulty and pain in micturition; Lung abscess; Acute mastitis; Rheumatic arthritis; Traumatic injury; Intercostal neuralgia; Epidemic hemorrhagic conjunctivitis; Skin ulcer swells.
Awns: sweet; Flat.Promoting blood circulation to restore menstrual flow.Main menoxenia; Amenorrhea; Post partum longtime lochia; Hemiplegia.
Flos Carthami: pungent, temperature.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Curled paralysis: micro-pungent, tepor.Slightly poisonous.Expelling wind and removing dampness, spleen invigorating is regulated the flow of vital energy, stasis-dispelling and pain-killing.For rheumatic arthritis, puerperal exposure to wind pain, puerperal abdonimal pain, bleed more than, dysmenorrhea, stomachache, stomachache, abdominal distention, dyspepsia, diarrhoea, oedema due to nephritis, traumatic injury.
Semen Sinapis Albae: acrid in the mouth, warm in nature, nontoxic.Enter the warp of liver, spleen, lung, stomach, the heart and envelope.Promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.
Cortex myricae nanae radicis skin: acid; Puckery; Cool in nature.Relieving diarrhea with astringents; Astringing to arrest bleeding; Removing obstruction in the collateral to relieve pain.Main dysentery; Have loose bowels; Proctoptosis; Metrorrhagia; Digestive tract hemorrhage; Rheumatalgia; Traumatic pain; Traumatic hemorrhage; Impetigo; Scabies; Burn due to hot liquid or fire.
Come into leaves Corallium Japonicum Kishinouye fruit: acrid in the mouth; Micro-hardship; Property is put down.Expelling wind and removing dampness; Removing obstruction in the collateral to relieve pain.Main air pain of dampness syndrome; Treating swelling and pain by traumatic injury.
Radix Lamiophlomidis Rotatae: bitter, is slightly cold.Invigorate blood circulation, clots absorbing, detumescence, hemostasis.Control and get injured by a fall muscles and bones, sprain one's back and frustrate gas, yellow fluid is amassed in joint.
Radix Buddlejae Butterflybush: warm in nature, acrid in the mouth is bitter, slightly poisonous.Blood circulation promoting and blood stasis dispelling.Control amenorrhea, lump in the abdomen, metrorrhagia, infantile malnutrition, parotitis.
Herba Camptosori Sibirici: light; Flat.Blood circulation promoting and blood stasis dispelling; Hemostasis; Removing toxic substances.Main thromboangiitis obliterans; Hemiplegia; Metrorrhagia; Traumatic hemorrhage; Neurodermatitis; Ulcer of the lower limb.
Bombyx mori L.: sweet in the mouth; Pungent; Warm in nature.Return liver; Spleen; Stomach warp.Expelling wind and removing dampness; Regulating the function of the stomach to resolve the turbidity; Promoting blood circulation to restore menstrual flow.Main air pain of dampness syndrome; Limbs are unsuccessful; Rubella pruritus; Vomit and diarrhoea and have a cramp; Amenorrhea; Metrorrhagia.
Radix Paeoniae Rubra: bitter, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, medicine has benefiting QI and nourishing blood, dispelling cold and dampness addiction, blood circulation and removing stasis, conciliation passages through which vital energy circulates, strengthening the body resistance, goes effect of silt tissue regeneration promoting.All have unique therapeutic effect to the various symptom of vasculitis, and cure rate is high.
Collect 100 Patients With Thromboangitis Obliterans, man 60 example, female 40 example; Age 30-65 year, average 38 years old; Take medicine 3 times on the one, within 6 hours, change once, 10 days each courses for the treatment of.
Efficacy evaluation:
Cure: clinical symptoms disappears substantially, and limbs wound surface heals completely, no sequel.
Effective: clinical symptoms is obviously improved, limbs wound healing or close healing, other is as ordinary person.
Effective: clinical symptom relief, limbs wound surface is close to healing or reduce.
Invalid: clinical symptoms and sign, without change, even worsen.
Result: cure 48 examples, effective 48 examples and effective 3 examples in treatment group in 100 routine patients, always effectively account for 99 examples, total effective rate 99%; As can be seen here, the present invention has very significant therapeutic effect to thromboangiitis obliterans.
Below enumerate several model case:
Case 1:
Grandson so-and-so, man, 37 years old, conscious right foot sent out cool, numb, and pain is not obvious, do not go any treatment.Rear 4th toe, also there is same symptom in the 5th toe, pain increases the weight of, and night, pain was obvious, and impact is had a rest, and travel distance is about the conscious calf of 10-20 rice and suppresses swollen, remission after having a rest.Then go county hospital to go to a doctor, be diagnosed as right lower extremity thromboangiitis obliterans, hospitalization more than 10 sky, giving quiet Radix Salviae Miltiorrhizae and expand blood vessel class medicine, (concrete medication is not quite clear), there is right foot Isosorbide-5-Nitrae in weak effect, 5 toe blackouts.The People's Hospital of Sui Qu city carries out two angiography of lower extremity arteries and tremulous pulse CT examination, and above-mentioned diagnosis is clear and definite, and gives dead point expansion blood vessel class medicine (concrete medication is not quite clear) treatment 9 days, DeGrain, the 2nd, also there is blackout in 3 toes and instep, for asking further diagnosis and treatment, special to our hospital.Adopt medicine of the present invention after 10 days, symptom is clearly better, and after 20 days, symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described, but the present invention is not limited to specific embodiment.
Embodiment 1:
A kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans, according to weight parts, prepared by following raw material of Chinese medicine: really 18 parts, ANLV 4 parts, Rhizoma Imperatae 4 parts, Cortex cercis chinensis 8 parts, Aleuritopteris argentea (Gmel.) Fee 8 parts, 8 parts, awns, 12 parts, Flos Carthami, curled paralysis 12 parts, Semen Sinapis Albae 12 parts, Cortex myricae nanae radicis skin 12 parts, the Corallium Japonicum Kishinouye that comes into leaves, Radix Lamiophlomidis Rotatae 18 parts, Radix Buddlejae Butterflybush 18 parts, Herba Camptosori Sibirici 18 parts, Bombyx mori L. 18 parts, Radix Paeoniae Rubra 18 parts.
Embodiment 2:
The Chinese medicine preparation of embodiment 1 is prepared in accordance with the following methods, step is as follows: take raw material of Chinese medicine according to formula and join in container, adds water to cover powder and soak 10 ~ 20 minutes, then adds water and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Above the implementation that specific embodiments is described is intended to specific descriptions of the present invention, can not be interpreted as it is limitation of the present invention.Under the teachings of the present invention, can make various variant on the basis of the embodiment described in detail, these variants all should be included within design of the present invention those of ordinary skill in the art.The present invention's scope required for protection is only limited by described claims.

Claims (2)

1. treat the Chinese medicine preparation of thromboangiitis obliterans for one kind, it is characterized in that: according to weight parts, prepared by following raw material of Chinese medicine: ANLV 3 ~ 5 parts, Rhizoma Imperatae 3 ~ 5 parts, Cortex cercis chinensis 5 ~ 10 parts, Aleuritopteris argentea (Gmel.) Fee 5 ~ 10 parts, 5 ~ 10 parts, awns, 10 ~ 15 parts, Flos Carthami, curled paralysis 10 ~ 15 parts, Semen Sinapis Albae 10 ~ 15 parts, Cortex myricae nanae radicis skin 10 ~ 15 parts, the Corallium Japonicum Kishinouye that comes into leaves really 15 ~ 20 parts, Radix Lamiophlomidis Rotatae 15 ~ 20 parts, Radix Buddlejae Butterflybush 15 ~ 20 parts, Herba Camptosori Sibirici 15 ~ 20 parts, Bombyx mori L. 15 ~ 20 parts, Radix Paeoniae Rubra 15 ~ 20 parts.
2. a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that: according to weight parts, formulated by following raw material of Chinese medicine: really 18 parts, ANLV 4 parts, Rhizoma Imperatae 4 parts, Cortex cercis chinensis 8 parts, Aleuritopteris argentea (Gmel.) Fee 8 parts, 8 parts, awns, 12 parts, Flos Carthami, curled paralysis 12 parts, Semen Sinapis Albae 12 parts, Cortex myricae nanae radicis skin 12 parts, the Corallium Japonicum Kishinouye that comes into leaves, Radix Lamiophlomidis Rotatae 18 parts, Radix Buddlejae Butterflybush 18 parts, Herba Camptosori Sibirici 18 parts, Bombyx mori L. 18 parts, Radix Paeoniae Rubra 18 parts.
CN201510078262.4A 2015-02-10 2015-02-10 Traditional Chinese medicine preparation for treating thromboangiitis obliterans Pending CN104740375A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031000A (en) * 2015-08-31 2015-11-11 霍传英 Preparation for preventing and treating thromboangiitis obliterans and preparing method
CN106334036A (en) * 2016-08-08 2017-01-18 青岛友诚高新技术有限公司 Traditional Chinese medicine composition for treating angeitis and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082324A1 (en) * 2002-03-28 2003-10-09 Maria De Lourdes Higuchi Prevention and treatment of mycoplasma-associated diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082324A1 (en) * 2002-03-28 2003-10-09 Maria De Lourdes Higuchi Prevention and treatment of mycoplasma-associated diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李建民等: "《外科护理学》", 31 January 2014, 清华大学出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031000A (en) * 2015-08-31 2015-11-11 霍传英 Preparation for preventing and treating thromboangiitis obliterans and preparing method
CN106334036A (en) * 2016-08-08 2017-01-18 青岛友诚高新技术有限公司 Traditional Chinese medicine composition for treating angeitis and preparation method thereof

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