CN108478778A - A kind of active pain-reliving spraying agent and preparation method thereof - Google Patents

A kind of active pain-reliving spraying agent and preparation method thereof Download PDF

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Publication number
CN108478778A
CN108478778A CN201810641572.6A CN201810641572A CN108478778A CN 108478778 A CN108478778 A CN 108478778A CN 201810641572 A CN201810641572 A CN 201810641572A CN 108478778 A CN108478778 A CN 108478778A
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root
parts
blood
reliving
safflower
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欧阳俊
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Hainan crocodile Industry Technology Co.,Ltd.
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Health (beijing) Health Industry Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K9/12—Aerosols; Foams
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants

Abstract

The invention discloses a kind of active pain-reliving spraying agents and preparation method thereof, including dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root, borneol, camphor, crocodile bone peptide, ethyl alcohol.Method be S1, by dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root ultra micro granulation it is spare；S2, comminuting matter is mixed evenly, then sprays ethyl alcohol, be packed into storage 48 hours in the cloth pocket sewed, enable its fermentation；After S3, fermentation, then the medicinal material for dressing up bag is soaked in the container of porcelain, the built-in alcohol of container；Environment temperature is 28 degree, and soaking time is 25~30 days；S4, after being soaked into, at brown liquid, then by medicine bag medicinal material take out squeezing, obtain pressed liquor；S5, it takes camphor, crocodile bone peptide to be dissolved into pressed liquor, obtains active pain-reliving spraying agent finished product.

Description

A kind of active pain-reliving spraying agent and preparation method thereof
Technical field
The present invention relates to health product technology field, a kind of active pain-reliving spraying agent and preparation method thereof is related in particular to.
Background technology
Rheumatism is a kind of systemic disease, and full name is " rheumatism ", is a kind of common disease frequently-occurring disease.Its type is numerous It is more including rheumatoid arthritis, lupus erythematosus, dermatomyositis, sclerderm, ankylosing spondylitis, rheumatic fever, infectional arthritis, soft Tissue rheumatism etc. more than 100 is planted, wherein especially with several diseases such as ankylosing spondylitis, rheumatoid arthritis, Osteoarthritis It is occurred frequently, and prognosis is poor, disability rate is relatively high.The cause of disease of these diseases is different, but there is common performance：Limbs, joint, flesh Meat pain, or with swelling, inconvenient activity.Patient pain is unbearably, handicapped, and is difficult to cure, many patients' shortages pair The understanding of rheumatism does not know how to prevent and go to a doctor, so that the state of an illness is from light to heavy, is finally difficult to reverse, it is serious cause it is residual Disease or even life-threatening.
So occur the rheumatism class drug of very multiple types on the market, and the validity and stability of rheumatism class drug At being increasingly everybody content of interest.
Invention content
It is an object of the invention to be directed to the shortcomings of the prior art, provide a kind of active pain-reliving spraying agent and its Preparation method, the healthcare function which has channels sootheing and network vessel quickening, relieves pain, promotes rehabilitation, validity and stabilization Property it is preferable, be suitable for uncomfortable caused by the pain such as traumatic injury, spur, arthralgia pain due to rheumatism, extremity numbness, lumbar muscle strain, stiff neck Crowd.
To achieve the goals above, the technical solution adopted in the present invention is：
A kind of active pain-reliving spraying agent, including it is dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, continuous Disconnected, Cortex Eucommiae, the fleece-flower root, camphor, crocodile bone peptide, ethyl alcohol.
As the improvement to above-mentioned technical proposal, based on quality component, the mass fraction of the active pain-reliving spraying agent component For：1~3 part of dragon's blood, 0.1~1 part of Radix Notoginseng, 1~3 part of Rhizoma Chuanxiong, 1~3 part of safflower, 2~5 parts of Caulis Spatholobi, 2~5 parts windproof, root of Dahurain angelica 0.1~3 part, 0.5~2 part of the root of Chinese clematis, 1~2 part of teasel root, 0.5~3 part of Cortex Eucommiae, 3~5 parts of the fleece-flower root, 0.1~1 part of camphor, crocodile 0.1~5 part of fish-bone peptide, 80~100 parts of ethyl alcohol.
As the improvement to above-mentioned technical proposal, based on quality component, the mass fraction of the active pain-reliving spraying agent component For：2 parts of dragon's blood, 0.5 part of Radix Notoginseng, 2 parts of Rhizoma Chuanxiong, 2 parts of safflower, 4 parts of Caulis Spatholobi, 3 parts windproof, 1.5 parts of the root of Dahurain angelica, 1.5 parts of the root of Chinese clematis, 1.5 parts of teasel root, 2 parts of Cortex Eucommiae, 4 parts of the fleece-flower root, 0.6 part of camphor, 2.5 parts of crocodile bone peptide, 90 parts of ethyl alcohol.
The step of present invention and preparation method for providing above-mentioned active pain-reliving spraying agent, the preparation method is：
S1, dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root are carried out Ultra micro granulation mechanical grinding is spare, and particle is made to be less than 8 μm；
S2, will crush after dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, He Shou Crow is mixed evenly, and then sprays ethyl alcohol, is packed into storage 48 hours in the cloth pocket sewed, enables its fermentation；
After S3, fermentation, then the medicinal material for dressing up bag is soaked in the container of porcelain, the built-in alcohol of container；Environment temperature Degree is 28 degree, and soaking time is 25~30 days；
S4, after being soaked into, at brown liquid, then by medicine bag medicinal material take out squeezing, obtain pressed liquor；
S5, it takes camphor, crocodile bone peptide to be dissolved into pressed liquor, obtains active pain-reliving spraying agent finished product.
Dragon's blood, for the exudation of babassu Sanguis Draxonis fruit resin it is processed be made, there is promoting blood circulation analgesic therapy, stagnation resolvation stops The effect of blood, myogenic sore.For traumatic injury, trusted subordinate's stasis caused pain, traumatic hemorrhage, sore do not hold back.
Radix Notoginseng, warm-natured, acrid flavour have the effect of scattered silt hemostasis, detumescence ding-tong.Can be used for treat bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, The diseases such as spitting of blood, haematemesis, traumatic hemorrhage, chest and abdomen shouting pain.And the flavone compound in Radix Notoginseng has improvement myocardial blood supply, increases The effect of blood vessel elasticity, coronary artery dilator, sitosterol and Daucosterol energy reducing blood lipid.Radix Notoginseng is often eaten, to coronary heart diseases and angina pectoris There is preventive and therapeutic action.《Detailed outline》：Hemostasis dissipates blood, analgesic therapy.Golden sword arrow wound, falls and flutters cane sore, and blood goes out more than person, chews rotten painting, or It is mixed for end, blood is i.e. only.Also main haematemesis, bleeding from five sense organs or subcutaneous tissue, lower blood, bloody flux, metrorrhagia, incessant menorrhea, postpartum extravesated blood not under, blood fortune, blood Bitterly, Akamu, carbuncle swells, tiger sting, all diseases of snakebite.《Jade seizes medicine solution》：With battalion stop blooding, the row stasis of blood of promoting blood circulation, row hemostasis and hold back new blood.
Rhizoma Chuanxiong is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, and wind-expelling pain-stopping, Rhizoma Chuanxiong pungent-warm perfume (or spice) is dry, walks without keeping, can Row dissipates, and uplink is pushed up up to mountain peak；Enter blood system again, downlink is up to the sea of blood.Promoting blood circulation effect is extensive, suitable for the various diseases of stagnation of blood stasis Disease；Wind-expelling pain-stopping, effectiveness is favourable, can control the diseases such as head wind headache, arthralgia pain due to rheumatism.It is the gas medicine in blood that former times people, which calls Rhizoma Chuanxiong, nearly says it Reside it is pungent dissipate, Xie Yu, it is sensible, analgesic etc. functions.
Safflower, invigorate blood circulation, removing blood stasis and analgesics, contribute to controlling through closing, dysmenorrhoea, lochia, chest impediment and cardialgia, stasis of blood, Chest side of body shouting pain, traumatic injury, sore swell and ache curative curative effect.There is the effect of promoting blood circulation and removing blood stasis, dissipate wet effect going to swell.
Caulis Spatholobi, bitter but slightly sweet taste, warm-natured, Return liver, the heart, kidney channel；Color it is red enter blood, matter profit row dissipate；With activating blood and relaxing tendons, blood-nourishing The effect of menstruation regulating；Arthralgia pain due to rheumatism is cured mainly, numb in every limb, quadriplegia, irregular menstruation, blockage of menstruation, dysmenorrhoea, Amenorrhea, leucocyte Reduce disease.
It is windproof, acrid flavour, sweet, slightly warm in nature.It expels pathogenic wind from the body surface, the effect of expel endogenous wind to relieve convulsion, relieving convulsion.For diseases caused by external factors exterior syndrome, rubella Itch, arthralgia pain due to rheumatism, lockjaw just, the insufficiency of the spleen with overabundance of dampness.
The root of Dahurain angelica, acrid flavour are warm-natured.Return lung, spleen, stomach.Wind-dispelling, eliminating dampness are subsided a swelling, analgesic.Control headache, pain in the supra-orbital bone, dentalgia, Nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.
The root of Chinese clematis has the effect of wind-damp dispelling, degrading the channel, the bone that disappears stalk.
Its slightly warm in nature of teasel root, it is bitter, pungent；Return liver and kidney channel.There is filling liver kidney, strengthening the bones and muscles, continuous injured, stop the effect of uterine bleeding, it can For treating the illnesss such as kidney deficiency and liver, soreness and weakness of waist and knees, arthralgia pain due to rheumatism, injury of tendon and muscle fracture, uterine bleeding, threatened abortion, injury from falling down.
Its is sweet in flavor for Cortex Eucommiae, warm-natured.Tonify the liver and kidney, strengthen muscles and bones, coordinating Chong and Conception Vessels, strengthen meridian and miscarriage prevention the effect of.Kidney can be treated Pain in waist and lower extremities caused by the deficiency of yang or aching and limp inability, born of the same parents' tire caused by liver- qi invasion is not solid, the wet equal diseases of itching of scrotum.With the internal rubbish of removing Rubbish reinforces human body cell metabolism, prevents muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol from reducing internal Fat restores blood vessel elasticity, diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system, raising white blood cell pharmacological action.
Fleece-flower root bitter sweet is puckery, tepor, nourishing the blood and yin；It relaxes bowel；Preventing malaria；Wind-dispelling；Removing toxic substances.Main deficiency of blood Light-headedness；The heart Throb with fear；Insomnia；The soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin；Poliosis；Tinnitus；Seminal emission；Dry constipation of intestines；Chronic malaria body void；Rubella itch；Sore Carbuncle；Scrofula；Hemorrhoid.
《Chinese book on Chinese herbal medicine》The load of volume 26：The first piece of Chinese alligator (Alligatorsinensis), medicine name Chinese alligator first, having The stasis of blood, disperse accumulation, insecticidal function cure mainly lump in the abdomen and gather, under metrorrhagia band, sore scabies, malignant sore, and intestines wind haemorrhoids.Alligator bone has strengthening the muscles and bones, replenishing essence The functions such as beneficial marrow, it is effective in cure to treating rheumatic ostealgia.Crocodile gelatine has the stress function and hematopoietic function to mouse, can significantly improve mouse Tolerance in high temperature and low temperature environment, and crocodile gelatine plays the role of enhancing physical stress function and increased platelets counts.It grinds Study carefully and show that crocodile bone meal contains the substances such as a large amount of calcium activated and phosphorus, can be used for preventing senile osteoporosis, children's rickets Deng.
Camphor has effects that orifice opening, qi stagnation removing, wards off that foul, desinsection is antipruritic, swelling and pain relieving, cures mainly mange itch, falls Injure the symptoms such as pain, toothache.
Compared with prior art, the beneficial effects of the invention are as follows：
The active pain-reliving spraying agent and preparation method thereof of the present invention, the comprehensive function generated using each component are dispelled with cold dispelling The active effect of wet, promoting blood circulation and removing blood stasis, detumescence ding-tong, latus rectum can effectively treat treating rheumatic ostealgia, the backache of rheumatic waist-leg, fall Beat damage, sprain, dampening, having aches in the limbs, whole body channels and collaterals pain, scapulohumeral periarthritis, the disease of arthroncus.Research has shown that the medical instrument Have that penetration power is strong, it is quick, it is convenient and practical the advantages that short treating period, good effect, received by many patients.
Specific implementation mode
Illustrate that embodiments of the present invention, those skilled in the art can be by this explanations by particular specific embodiment below Content disclosed by book understands other advantages and effect of the present invention easily.
Embodiment 1：The preparation method of the active pain-reliving spraying agent of the present embodiment is：
S1, dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root are carried out Ultra micro granulation mechanical grinding is spare, and particle is made to be less than 8 μm；
S2, will crush after dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, He Shou Crow is mixed evenly, and then sprays ethyl alcohol, is packed into storage 48 hours in the cloth pocket sewed, enables its fermentation；
After S3, fermentation, then the medicinal material for dressing up bag is soaked in the container of porcelain, the built-in alcohol of container；Environment temperature Degree is 28 degree, and soaking time is 25~30 days；
S4, after being soaked into, at brown liquid, then by medicine bag medicinal material take out squeezing, obtain pressed liquor；
S5, it takes camphor, crocodile bone peptide to be dissolved into pressed liquor, obtains active pain-reliving spraying agent finished product；
Based on quality component, the mass fraction of the active pain-reliving spraying agent component is：1 part of dragon's blood, 0.1 part of Radix Notoginseng, Rhizoma Chuanxiong 1 Part, 1 part of safflower, 2 parts of Caulis Spatholobi, 2 parts windproof, 0.1 part of the root of Dahurain angelica, 0.5 part of the root of Chinese clematis, 1 part of teasel root, 0.5 part of Cortex Eucommiae, the fleece-flower root 3 Part, 0.1 part of camphor, 0.1 part of crocodile bone peptide, 80 parts of ethyl alcohol.
Embodiment 2：The preparation method of the active pain-reliving spraying agent of the present embodiment is：
S1, dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root are carried out Ultra micro granulation mechanical grinding is spare, and particle is made to be less than 8 μm；
S2, will crush after dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, He Shou Crow is mixed evenly, and then sprays ethyl alcohol, is packed into storage 48 hours in the cloth pocket sewed, enables its fermentation；
After S3, fermentation, then the medicinal material for dressing up bag is soaked in the container of porcelain, the built-in alcohol of container；Environment temperature Degree is 28 degree, and soaking time is 25~30 days；
S4, after being soaked into, at brown liquid, then by medicine bag medicinal material take out squeezing, obtain pressed liquor；
S5, it takes camphor, crocodile bone peptide to be dissolved into pressed liquor, obtains active pain-reliving spraying agent finished product；
Based on quality component, the mass fraction of the active pain-reliving spraying agent component is：3 parts of dragon's blood, 1 part of Radix Notoginseng, Rhizoma Chuanxiong 3 Part, 3 parts of safflower, 5 parts of Caulis Spatholobi, 5 parts windproof, 3 parts of the root of Dahurain angelica, 2 parts of the root of Chinese clematis, 2 parts of teasel root, 3 parts of Cortex Eucommiae, 5 parts of the fleece-flower root, camphor 1 part, 5 parts of crocodile bone peptide, 100 parts of ethyl alcohol.
Embodiment 3：
S1, dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root are carried out Ultra micro granulation mechanical grinding is spare, and particle is made to be less than 8 μm；
S2, by dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root, crocodile Fish-bone peptide is mixed evenly, and obtains powder mixture；
S3, it takes camphor that ethyl alcohol is added to make dissolving, obtains camphor ethyl alcohol lysate；
S4, by powder mixture, mixed, camphor ethyl alcohol lysate is stirred continuously after mixing to paste, is coated on non-woven fabrics and is made At active pain-reliving spraying agent；S1, by dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, what Tuber of multiflower knotweed progress ultra micro granulation mechanical grinding is spare, and particle is made to be less than 8 μm；
S2, will crush after dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, He Shou Crow is mixed evenly, and then sprays ethyl alcohol, is packed into storage 48 hours in the cloth pocket sewed, enables its fermentation；
After S3, fermentation, then the medicinal material for dressing up bag is soaked in the container of porcelain, the built-in alcohol of container；Environment temperature Degree is 28 degree, and soaking time is 25~30 days；
S4, after being soaked into, at brown liquid, then by medicine bag medicinal material take out squeezing, obtain pressed liquor；
S5, it takes camphor, crocodile bone peptide to be dissolved into pressed liquor, obtains active pain-reliving spraying agent finished product；
The mass fraction of the active pain-reliving spraying agent component is：2 parts of dragon's blood, 0.5 part of Radix Notoginseng, 2 parts of Rhizoma Chuanxiong, 2 parts of safflower, chicken 4 parts of blood rattan, 3 parts windproof, 1.5 parts of the root of Dahurain angelica, 1.5 parts of the root of Chinese clematis, 1.5 parts of teasel root, 2 parts of Cortex Eucommiae, 4 parts of the fleece-flower root, 0.6 part of camphor, 2.5 parts of crocodile bone peptide, 90 parts of ethyl alcohol.
The active pain-reliving spraying agent and preparation method thereof of the present invention, the comprehensive function generated using each component are dispelled with cold dispelling The active effect of wet, promoting blood circulation and removing blood stasis, detumescence ding-tong, latus rectum can effectively treat treating rheumatic ostealgia, the backache of rheumatic waist-leg, fall Beat damage, sprain, dampening, having aches in the limbs, whole body channels and collaterals pain, scapulohumeral periarthritis, the disease of arthroncus.Research has shown that the medical instrument Have that penetration power is strong, it is quick, it is convenient and practical the advantages that short treating period, good effect, received by many patients.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe The personage for knowing this technology can all carry out modifications and changes to above-described embodiment without violating the spirit and scope of the present invention.Cause This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as At all equivalent modifications or change, should by the present invention claim be covered.

Claims (4)

1. a kind of active pain-reliving spraying agent, it is characterised in that：Its Main Components includes dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, prevents Wind, the root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root, camphor, crocodile bone peptide, ethyl alcohol.
2. active pain-reliving spraying agent according to claim 1, it is characterised in that：Based on quality component, the active pain of dispelling is sprayed The mass fraction of agent component is：1~3 part of dragon's blood, 0.1~1 part of Radix Notoginseng, 1~3 part of Rhizoma Chuanxiong, 1~3 part of safflower, Caulis Spatholobi 2~5 Part, 2~5 parts windproof, 0.1~3 part of the root of Dahurain angelica, 0.5~2 part of the root of Chinese clematis, 1~2 part of teasel root, 0.5~3 part of Cortex Eucommiae, the fleece-flower root 3~5 Part, 0.1~1 part of camphor, 0.1~5 part of crocodile bone peptide, 80~100 parts of ethyl alcohol.
3. active pain-reliving spraying agent according to claim 2, it is characterised in that：Based on quality component, the active pain of dispelling is sprayed The mass fraction of agent component is：2 parts of dragon's blood, 0.5 part of Radix Notoginseng, 2 parts of Rhizoma Chuanxiong, 2 parts of safflower, 4 parts of Caulis Spatholobi, the 3 parts windproof, root of Dahurain angelica 1.5 parts, 1.5 parts of the root of Chinese clematis, 1.5 parts of teasel root, 2 parts of Cortex Eucommiae, 4 parts of the fleece-flower root, 0.6 part of camphor, 2.5 parts of crocodile bone peptide, ethyl alcohol 90 Part.
4. a kind of preparation method preparing the active pain-reliving spraying agent such as claims 1 or 2 or 3, it is characterised in that：The preparation method The step of be：
S1, dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root are subjected to ultra micro It is spare that granulation machines are levigate, and particle is made to be less than 8 μm；
S2, dragon's blood, Radix Notoginseng, Rhizoma Chuanxiong, safflower, Caulis Spatholobi, the windproof, root of Dahurain angelica, the root of Chinese clematis, teasel root, Cortex Eucommiae, the fleece-flower root after crushing are mixed Conjunction stirs evenly, and then sprays ethyl alcohol, is packed into storage 48 hours in the cloth pocket sewed, enables its fermentation；
After S3, fermentation, then the medicinal material for dressing up bag is soaked in the container of porcelain, the built-in hexanol of container；Environment temperature is 28 degree, soaking time is 25~30 days；
S4, after being soaked into, at brown liquid, then by medicine bag medicinal material take out squeezing, obtain pressed liquor：
S5, it takes camphor, crocodile bone peptide to be dissolved into pressed liquor, obtains active pain-reliving spraying agent finished product.
CN201810641572.6A 2018-06-20 2018-06-20 A kind of active pain-reliving spraying agent and preparation method thereof Pending CN108478778A (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101711835A (en) * 2008-10-08 2010-05-26 贵州地道药业有限公司 Formula of traditional Chinese medicines for treating soft tissue injury and method for preparing preparation thereof
CN102266459A (en) * 2011-07-18 2011-12-07 李宏干 Chinese medicinal spray for eliminating trauma gall and preparation method
CN103463221A (en) * 2013-09-27 2013-12-25 通化斯威药业股份有限公司 External use analgesic liquid capable of activating blood, dissolving stasis and relieving swelling and pain and preparing method thereof
CN105193916A (en) * 2015-10-28 2015-12-30 广州善康生物科技有限公司 Crocodile extract composition for treating rheumatoid ostealgia, and preparation method thereof
CN105412893A (en) * 2015-12-30 2016-03-23 李庆河 Jingutong spray and making method thereof
CN106666480A (en) * 2017-03-17 2017-05-17 徐少云 Crocodile bond meal and preparation method thereof
CN107625868A (en) * 2017-10-17 2018-01-26 贵州康珠药业有限公司 Chinese medicine composition, preparation method and applications and Chinese medicine preparation and preparation method thereof
CN107951906A (en) * 2017-11-08 2018-04-24 海南国瑞堂中药制药有限公司 A kind of crocodile first glue and preparation method thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101711835A (en) * 2008-10-08 2010-05-26 贵州地道药业有限公司 Formula of traditional Chinese medicines for treating soft tissue injury and method for preparing preparation thereof
CN102266459A (en) * 2011-07-18 2011-12-07 李宏干 Chinese medicinal spray for eliminating trauma gall and preparation method
CN103463221A (en) * 2013-09-27 2013-12-25 通化斯威药业股份有限公司 External use analgesic liquid capable of activating blood, dissolving stasis and relieving swelling and pain and preparing method thereof
CN105193916A (en) * 2015-10-28 2015-12-30 广州善康生物科技有限公司 Crocodile extract composition for treating rheumatoid ostealgia, and preparation method thereof
CN105412893A (en) * 2015-12-30 2016-03-23 李庆河 Jingutong spray and making method thereof
CN106666480A (en) * 2017-03-17 2017-05-17 徐少云 Crocodile bond meal and preparation method thereof
CN107625868A (en) * 2017-10-17 2018-01-26 贵州康珠药业有限公司 Chinese medicine composition, preparation method and applications and Chinese medicine preparation and preparation method thereof
CN107951906A (en) * 2017-11-08 2018-04-24 海南国瑞堂中药制药有限公司 A kind of crocodile first glue and preparation method thereof

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