CN108478683A - A kind of beverage for final vacuum of performing the operation - Google Patents
A kind of beverage for final vacuum of performing the operation Download PDFInfo
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- CN108478683A CN108478683A CN201810261135.1A CN201810261135A CN108478683A CN 108478683 A CN108478683 A CN 108478683A CN 201810261135 A CN201810261135 A CN 201810261135A CN 108478683 A CN108478683 A CN 108478683A
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- beverage
- final vacuum
- concentration
- jujube
- hawthorn
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- 235000013361 beverage Nutrition 0.000 title claims abstract description 25
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 16
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 16
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims abstract description 16
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims abstract description 16
- 235000009685 Crataegus X maligna Nutrition 0.000 claims abstract description 16
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims abstract description 16
- 235000009486 Crataegus bullatus Nutrition 0.000 claims abstract description 16
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims abstract description 16
- 235000009682 Crataegus limnophila Nutrition 0.000 claims abstract description 16
- 235000004423 Crataegus monogyna Nutrition 0.000 claims abstract description 16
- 235000002313 Crataegus paludosa Nutrition 0.000 claims abstract description 16
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims abstract description 16
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 16
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 16
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 16
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 16
- 210000000582 semen Anatomy 0.000 claims abstract description 15
- 239000000126 substance Substances 0.000 claims abstract description 13
- 240000000171 Crataegus monogyna Species 0.000 claims abstract 3
- 240000008866 Ziziphus nummularia Species 0.000 claims abstract 3
- 239000003814 drug Substances 0.000 claims description 28
- 229940079593 drug Drugs 0.000 claims description 27
- 239000000284 extract Substances 0.000 claims description 14
- 235000012907 honey Nutrition 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 9
- 238000003809 water extraction Methods 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims 1
- 229940126678 chinese medicines Drugs 0.000 abstract description 2
- 210000002784 stomach Anatomy 0.000 description 19
- 241001092040 Crataegus Species 0.000 description 13
- 241001247821 Ziziphus Species 0.000 description 13
- 210000000952 spleen Anatomy 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 241000699666 Mus <mouse, genus> Species 0.000 description 7
- 230000000968 intestinal effect Effects 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000001187 pylorus Anatomy 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000003304 gavage Methods 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 230000035764 nutrition Effects 0.000 description 4
- 210000000813 small intestine Anatomy 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000030136 gastric emptying Effects 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 238000012449 Kunming mouse Methods 0.000 description 2
- 101100288498 Mus musculus Large1 gene Proteins 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 208000019790 abdominal distention Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 206010016766 flatulence Diseases 0.000 description 2
- 230000007661 gastrointestinal function Effects 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000001141 propulsive effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
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- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 210000002318 cardia Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000006278 hypochromic anemia Diseases 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
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- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention belongs to the field of Chinese medicines, are related to a kind of beverage for final vacuum of performing the operation.The beverage is prepared by the bulk pharmaceutical chemicals of following parts by weight:5 15g of stir-baked SEMEN RAPHANI, 10 20g of dried orange peel, 10 20g of hawthorn, 10 20g of Chinese yam, 10 20g of jujube, 10 20g of fried cassia are made.The beverage can be used for the patient of operation final vacuum.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of beverage for final vacuum of performing the operation and its preparation side
Method.
Background technology
Flatulence is very common symptom after operation, extremely related with gastrointestinal function.In surgical procedure, the gastrointestinal tract of patient
Exposure, has it certain irritation;Meanwhile different degrees of stimulation may be generated in operative process to it, so as to cause
Gastrointestinal function declines, wriggling reduced capability, and then causes flatulence.It is mainly shown as abdominal distension, is unable to normal exhaust.Postoperative need
The patient morbidity's higher to be liied in bed.The symptom of some patientss can voluntarily be alleviated, but still there have some patientss that can occur to be various other
Complication, influence patient more after, be unfavorable for disease recovery.Therefore, it is very necessary to patient that the disease is treated in time.
Invention content
The technical problem to be solved by the present invention is to patient's operation final vacuum hardly possiblies, provide a kind of beverage for final vacuum of performing the operation
And preparation method thereof.
A kind of beverage for final vacuum of performing the operation, it is prepared by the bulk pharmaceutical chemicals of following parts by weight:Stir-baked SEMEN RAPHANI
5-15g, dried orange peel 10-20g, hawthorn 10-20g, Chinese yam 10-20g, jujube 10-20g, the sub- 10-20g of fried cassia.
A kind of beverage for final vacuum of performing the operation, it is prepared by the bulk pharmaceutical chemicals of following parts by weight:Stir-baked SEMEN RAPHANI
10g, dried orange peel 16g, hawthorn 16g, Chinese yam 16g, jujube 16g, the sub- 16g of fried cassia.
A kind of preparation method of beverage for final vacuum of performing the operation, takes stir-baked SEMEN RAPHANI, dried orange peel, hawthorn, Chinese yam, jujube, stir-fry
The bulk pharmaceutical chemicals such as cassia seed add 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration
It is 0.45g mL to be equivalent to crude drug-1。
Each bulk pharmaceutical chemicals effect is as follows:
Stir-baked SEMEN RAPHANI:It is pungent, sweet, flat.Returns spleen, stomach, lung, large intestine channel.Promoting digestion, lowering the adverse-rising QI and eliminating phlegm.For stagnation of QI due to dyspepsia, gastral cavity abdomen is swollen
Expire, diarrhea, weight after diarrhea, cough ant phlegm, circulation of vital energy in the wrong direction asthma is full etc..
Dried orange peel:Acrid, bitter, warm, returns spleen, stomach, lung channel.In qi-regulating tune, stopping nausea and vomiting by lowering the adverse flow of QI is eliminating dampness and eliminating phlegm.For chest and diaphragm expire vexed, gastral cavity
Abdominal distention and pain, do not feel like eating, vomiting etc..
Hawthorn:Sour, sweet, tepor.Returns spleen, stomach, Liver Channel.Food digesting stomach fortifying, scattered stasis.For eating accumulation, abdominal distention,
Dysentery, hernia swelling and pain etc..
Chinese yam:It is sweet, flat.Returns spleen, lung, kidney channel.Supplementing qi and nourishing yin, tonifying spleen lung kidney, treating spontaneous emission and leukorrhagia.For weakness of the spleen and stomach, lung
The weak card of kidney deficiency, yin asthenia generating intrinsic heat, polydipsia, the diabete of frequent urination.
Jujube:It is sweet, warm.Returns spleen, stomach.Tonifying middle-Jiao and Qi, nourishing blood and tranquilization mitigate pharmacological property.For spleen eating less loose stool, burnout
Weak, blood deficiency chlorosis and women's internal organs, mind is uneasy, protection healthy tendency etc.
Fried cassia:Salty hardship, Pingliang are nontoxic.Expelling wind and clearing away heat, detoxification and promoting urination.It is clinically used for anemopyretic cold, influenza, acute conjunctiva
Inflammation, jaundice with damp-heat pathogen, acute and chronic nephritis, under, scrofula, sore carbuncle furuncle, the diseases such as mastitis.
Invention achieves unexpected technique effects for research verification through the following experiment:
Drug of the present invention is used for the experimental study of abdomen exhaust
1 data and method
1.1 experiment material
Kunming mouse, half male and half female, 18~22g of weight, Shandong Traditional Chinese Medicine University's animal center offer are provided.Credit number:
(scxk (Shandong) 20130009).
1.2 instruments and reagent
Electronic analytical balance(Mei Tele companies), CMC-Na4g, milk powder 8g, sugared 4g, starch 4g, activated carbon 1.5g, distillation
Water 125mL is made into nutrition paste, measures nutrition paste density 1.02gmL-1。
1.3 test medicine
(1)Beverage of the present invention:Stir-baked SEMEN RAPHANI 10g, dried orange peel 16g, hawthorn 16g, Chinese yam 16g, jujube 16g, the sub- 16g of fried cassia, add
Twice, mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration is equivalent to crude drug and is for 18 times of amount water extractions
0.45g•mL-1。
(2)Drugs compared composition 1:Dried orange peel 18g, hawthorn 18g, Chinese yam 18g, jujube 18g, the sub- 18g of fried cassia, add 18
Twice, mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration is equivalent to crude drug and is the extraction of amount water again
0.45g•mL-1。
(3)Drugs compared composition 2:Stir-baked SEMEN RAPHANI 12.2g, it hawthorn 19.45g, Chinese yam 19.45g, jujube 19.45g, fries
Cassia seed 19.45g adds 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration phase
When in crude drug be 0.45g mL-1。
(4)Drugs compared composition 3:Stir-baked SEMEN RAPHANI 12.2g, it dried orange peel 19.45g, Chinese yam 19.45g, jujube 19.45g, fries
Cassia seed 19.45g adds 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration phase
When in crude drug be 0.45g mL-1。
(5)Drugs compared composition 4:Stir-baked SEMEN RAPHANI 12.2g, it dried orange peel 19.45g, hawthorn 19.45g, jujube 19.45g, fries
Cassia seed 19.45g adds 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration phase
When in crude drug be 0.45g mL-1。
(6)Drugs compared composition 5:Stir-baked SEMEN RAPHANI 12.2g, it dried orange peel 19.45g, hawthorn 19.45g, Chinese yam 19.45g, fries
Cassia seed 19.45g adds 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration phase
When in crude drug be 0.45g mL-1。
(7)Drugs compared composition 6:It is stir-baked SEMEN RAPHANI 12.2g, dried orange peel 19.45g, hawthorn 19.45g, Chinese yam 19.45g, big
Jujube 19.45g adds 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration is equivalent to
Crude drug is 0.45g mL-1。
(8)Drugs compared composition 7:Houpo Paiqi Mixture(RuiYang Pharmacy Co., Ltd, Chinese medicines quasi-word Z
20050563), it is 0.45g mL that concentration, which is made, and is equivalent to crude drug-1。
(9)Control group 8:Take same amount of distilled water as a contrast.
1.4 experimental method
To the influence in body mouse gastric emptying, Intestinal pushing
(1) determination of dosage
Every mouse large dosage group test liquid solution 0.03mL is calculated by body surface area, it is contemplated that the damage in extraction separation process
It loses.Give 18 respectively through trial test(2/every group)4 times of mouse large dosage, 6 times, 8 times, 10 times, each mouse is without exception
Reaction, it is final to determine that dosage is 0.3ml.
(2) method
108 kunming mices, half male and half female are randomly divided into beverage group of the present invention, drugs compared group 1-7, control group 8, amount to 9
Group, every group 12.Before mouse experiment fasting for 24 hours, free water during fasting.Using administration by gavage, test group of animals gavages respectively
A concentration of 0.45gmL-1Beverage 0.3ml of the present invention, drugs compared group 7 gavage a concentration of 0.45gmL-1Cortex Magnoliae Officinalis is vented liquid
0.3ml, control group gavage distilled water 0.3ml.Lh after administration gives semisolid nutrition and pastes, cervical dislocation after every 0.4mL, 20min
It puts to death.Stomach cardia and pylorus are ligatured, takes stomach to weigh to obtain stomach gross weight, then body of stomach is cut off along greater curvature, after washing away gastric content
It wipes and dry weighs to obtain stomach net weight.Using stomach gross weight and the difference of stomach net weight as residue weight in stomach, in stomach, residue, which accounts for, fills half admittedly
The weight percent of body paste is residual rate in stomach.It is rapid simultaneously to take out small intestine, it is directly laid on blank sheet of paper after gently removing, measures pylorus
The distance in forward position is pasted to ileocecum portion overall length and pylorus to black semisolid.The distance in forward position is pasted with pylorus to black semisolid
(Promote length)Pylorus is accounted for ileocecus overall length(Small intestine overall length)Percentage be Intestinal propulsive rate.
Residual rate in stomach=(Stomach gross weight-stomach net weight)/ filled nutrition paste weight × 100%
Intestinal propulsive rate=propulsion length/small intestine overall length × 100%
(3)Experimental result
Analysis of experimental results software:SPSS 13.0
1 beverage of the present invention of table to mouse gastric emptying influence (±s , n =12)
Note: a:Compared with the control group, P<0.01, significant difference;b:Compared with drugs compared group 7, P<0.05, significant difference;
c:Compared with beverage group of the present invention, P<0.05, significant difference.
2 beverage of the present invention of table to mouse Intestinal pushing influence (±s , n =12)
Note:a:Compared with the control group, P<0.01, significant difference;b:Compared with drugs compared group 7, P<0.05, significant difference; c:
Compared with beverage group of the present invention, P<0.05, significant difference.
The experimental results showed that:Residual rate, Intestinal pushing Lv and control group, drugs compared group have significantly in beverage group stomach of the present invention
Sex differernce has apparent progradation, and mouse Intestinal pushing power can be remarkably reinforced.
1.5 conclusion
Beverage group of the present invention can significantly promote mouse gastric emptying and can enhance small intestine push power.And present invention operation heel row
Gas beverage flavour of a drug form and dosage perfection collocation, have obvious synergistic function together, the missing of any medicine simply is all
The whole curative effect that pharmaceutical composition can be substantially reduced has good result to postoperative bowel patient.
Specific implementation mode
1, a kind of beverage for final vacuum of performing the operation, it is made of the bulk pharmaceutical chemicals of following parts by weight:Stir-baked SEMEN RAPHANI 5g,
Dried orange peel 17g, hawthorn 17g, Chinese yam 17g, jujube 17g, the sub- 17g of fried cassia, preparation method are to take bulk pharmaceutical chemicals, and 18 times of amount water is added to carry
It takes twice, mixed extract, concentrates, add honey 14ml, be settled to 200ml, it is 0.45gmL that concentration, which is equivalent to crude drug,-1。
2, a kind of beverage for final vacuum of performing the operation, it is made of the bulk pharmaceutical chemicals of following parts by weight:Stir-baked SEMEN RAPHANI
10g, dried orange peel 16g, hawthorn 16g, Chinese yam 16g, jujube 16g, the sub- 16g of fried cassia, preparation method are to take bulk pharmaceutical chemicals, add 18 times of amounts
Water extracts twice, mixed extract, and concentration adds honey 14ml, is settled to 200ml, it is 0.45g that concentration, which is equivalent to crude drug,
mL-1。
3, a kind of beverage for final vacuum of performing the operation, it is made of the bulk pharmaceutical chemicals of following parts by weight:Stir-baked SEMEN RAPHANI
15g, dried orange peel 15g, hawthorn 15g, Chinese yam 15g, jujube 15g, the sub- 15g of fried cassia, preparation method are to take bulk pharmaceutical chemicals, add 18 times of amounts
Water extracts twice, mixed extract, and concentration adds honey 14ml, is settled to 200ml, it is 0.45g that concentration, which is equivalent to crude drug,
mL-1。。
Claims (3)
1. a kind of beverage for final vacuum of performing the operation, it is characterised in that:It is made of the bulk pharmaceutical chemicals of following parts by weight:Fry Lay
Fu 5-15g, dried orange peel 10-20g, hawthorn 10-20g, Chinese yam 10-20g, jujube 10-20g, the sub- 10-20g of fried cassia.
2. according to the beverage for final vacuum of performing the operation described in claim 1, it is characterised in that:It is by following parts by weight
Bulk pharmaceutical chemicals composition:Stir-baked SEMEN RAPHANI 10g, dried orange peel 16g, hawthorn 16g, Chinese yam 16g, jujube 16g, the sub- 16g of fried cassia.
3. the preparation method of the beverage according to claim 1 or 2 for final vacuum of performing the operation, it is characterised in that:Take raw material
Medicine adds 18 times of amount water extractions twice, and mixed extract, concentration adds honey 14ml, is settled to 200ml, concentration is equivalent to crude drug
For 0.45gmL-1。
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CN201810261135.1A CN108478683B (en) | 2018-03-28 | 2018-03-28 | Beverage for postoperative gas exhaust |
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CN201810261135.1A CN108478683B (en) | 2018-03-28 | 2018-03-28 | Beverage for postoperative gas exhaust |
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CN108478683A true CN108478683A (en) | 2018-09-04 |
CN108478683B CN108478683B (en) | 2020-11-17 |
Family
ID=63316789
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CN201810261135.1A Active CN108478683B (en) | 2018-03-28 | 2018-03-28 | Beverage for postoperative gas exhaust |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1138990A (en) * | 1995-06-27 | 1997-01-01 | 郑铁保健食品厂 | Oral liquid for preventing and curing infantile anorexia and its prepn |
CN1754453A (en) * | 2004-09-30 | 2006-04-05 | 刘滨德 | Health food with function of promoting and eliminating indigestion, mositurizing bowel and defaecation |
-
2018
- 2018-03-28 CN CN201810261135.1A patent/CN108478683B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1138990A (en) * | 1995-06-27 | 1997-01-01 | 郑铁保健食品厂 | Oral liquid for preventing and curing infantile anorexia and its prepn |
CN1754453A (en) * | 2004-09-30 | 2006-04-05 | 刘滨德 | Health food with function of promoting and eliminating indigestion, mositurizing bowel and defaecation |
Non-Patent Citations (1)
Title |
---|
冉小库等: "茯苓对正常小鼠胃肠功能的影响", 《中国现代中药》 * |
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Effective date of registration: 20220110 Address after: 266035 00 (duplex), No. 710-35, Tongxing Road, Laoshan District, Qingdao City, Shandong Province Patentee after: Qingdao Pusheng Runbang Pharmaceutical Technology Co.,Ltd. Address before: 266199 household 204, unit 5, No. 96, Fushan Road, Licang District, Qingdao City, Shandong Province Patentee before: QINGDAO XINLIJIAN BIOTECHNOLOGY CO.,LTD. |