CN108478551A - 用于治疗糖尿病和相关病症的方法和组合物 - Google Patents

用于治疗糖尿病和相关病症的方法和组合物 Download PDF

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Publication number
CN108478551A
CN108478551A CN201810135122.XA CN201810135122A CN108478551A CN 108478551 A CN108478551 A CN 108478551A CN 201810135122 A CN201810135122 A CN 201810135122A CN 108478551 A CN108478551 A CN 108478551A
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CN
China
Prior art keywords
glutamine
diabetes
salt
compositions
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810135122.XA
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English (en)
Chinese (zh)
Inventor
新原丰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emmaus Medical Inc
Original Assignee
Emmaus Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48470183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN108478551(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Emmaus Medical Inc filed Critical Emmaus Medical Inc
Publication of CN108478551A publication Critical patent/CN108478551A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201810135122.XA 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物 Pending CN108478551A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161629633P 2011-11-21 2011-11-21
US61/629,633 2011-11-21
CN201280056939.9A CN103945858A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201280056939.9A Division CN103945858A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物

Publications (1)

Publication Number Publication Date
CN108478551A true CN108478551A (zh) 2018-09-04

Family

ID=48470183

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201810135122.XA Pending CN108478551A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物
CN201810134012.1A Pending CN108354916A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物
CN201280056939.9A Pending CN103945858A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201810134012.1A Pending CN108354916A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物
CN201280056939.9A Pending CN103945858A (zh) 2011-11-21 2012-11-17 用于治疗糖尿病和相关病症的方法和组合物

Country Status (10)

Country Link
US (2) US20130143968A1 (https=)
EP (2) EP3437649A1 (https=)
JP (4) JP6089042B2 (https=)
CN (3) CN108478551A (https=)
BR (1) BR112014011898A2 (https=)
ES (1) ES2785094T3 (https=)
HK (1) HK1257401A1 (https=)
IN (1) IN2014KN01037A (https=)
PH (2) PH12020550726B1 (https=)
WO (1) WO2013077893A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
IL296055A (en) 2017-08-14 2022-10-01 Axcella Health Inc Amino acid compositions for the treatment of liver disease
MA52971A (fr) 2018-06-20 2021-04-28 Axcella Health Inc Compositions et procédés pour le traitement de l'infiltration de graisse dans le muscle

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101472579A (zh) * 2006-04-22 2009-07-01 霍利斯-伊登医药公司 药物和用途
WO2010107307A1 (en) * 2009-03-20 2010-09-23 Glnp (Generic Life Quality Enhancing Niche Products) Holding B.V. Kit of parts comprising l-glutamine and egcg
WO2011038014A2 (en) * 2009-09-23 2011-03-31 Biokier, Inc. Composition and method for treatment of diabetes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6031000A (en) * 1998-06-23 2000-02-29 Iowa State University Research Foundation, Inc. Composition comprising β-hydroxy-β-methylbutyric acid and at least one amino acid and methods of use
CA2418543A1 (en) * 2001-06-27 2003-01-09 Probiodrug Ag New dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents
SE0201713D0 (sv) * 2001-11-23 2002-06-06 Gramineer Internat Ab New methods and use III
TWI351278B (en) * 2002-03-01 2011-11-01 Nisshin Pharma Inc Agent for preventing and treating of liver disease
US20070025953A1 (en) * 2005-07-27 2007-02-01 Jones Michael R Co-therapy for diabetic conditions
EP2077110A4 (en) * 2006-09-29 2012-06-27 Ajinomoto Kk GLUTAMINE-CONTAINING COMPOSITION FOR INCREASING BLOOD FLOW
US20080221074A1 (en) * 2006-11-17 2008-09-11 Jaime Flores-Riveros Drug Screen and Treatment Method
EP2057905A1 (en) * 2007-11-12 2009-05-13 TIMA Foundation Composition for moderating Triglyceride and Cholesterol Levels
RS56054B1 (sr) * 2009-01-12 2017-09-29 Biokier Inc Smeša i metod za lečenje dijabetesa

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101472579A (zh) * 2006-04-22 2009-07-01 霍利斯-伊登医药公司 药物和用途
WO2010107307A1 (en) * 2009-03-20 2010-09-23 Glnp (Generic Life Quality Enhancing Niche Products) Holding B.V. Kit of parts comprising l-glutamine and egcg
WO2011038014A2 (en) * 2009-09-23 2011-03-31 Biokier, Inc. Composition and method for treatment of diabetes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DORIT SAMOCHA-BONET等: "Glutamine Reduces Postprandial Glycemia and Augments the Glucagon-Like Peptide-1 Response in Type 2 Diabetes Patients", 《THE JOURNAL OF NUTRITION》 *
张景义主编: "《糖尿病防治新视点》", 31 July 2007, 天津科学技术出版社 *
梁晓春、王普艳主编: "《糖尿病药物使用手册》", 31 January 2011, 北京出版社 *
邹大进著: "《你能战胜糖尿病》", 31 October 2011, 第二军医大学出版社 *

Also Published As

Publication number Publication date
EP2782588B1 (en) 2020-04-15
BR112014011898A2 (pt) 2017-05-16
US20130143968A1 (en) 2013-06-06
ES2785094T3 (es) 2020-10-05
HK1257401A1 (zh) 2019-10-18
EP2782588A4 (en) 2015-05-20
PH12014501052A1 (en) 2014-06-30
EP3437649A1 (en) 2019-02-06
US20190192463A1 (en) 2019-06-27
IN2014KN01037A (en) 2015-10-09
CN108354916A (zh) 2018-08-03
CN103945858A (zh) 2014-07-23
JP2014533689A (ja) 2014-12-15
JP6089042B2 (ja) 2017-03-01
WO2013077893A1 (en) 2013-05-30
JP6389495B2 (ja) 2018-09-12
EP2782588A1 (en) 2014-10-01
JP6550160B2 (ja) 2019-07-24
JP2018199692A (ja) 2018-12-20
PH12020550726B1 (en) 2022-11-09
JP2017052766A (ja) 2017-03-16
PH12020550726A1 (en) 2021-06-14
JP2018115175A (ja) 2018-07-26
PH12014501052B1 (en) 2020-10-09

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Application publication date: 20180904

RJ01 Rejection of invention patent application after publication