CN108474874B - 用于数字病理学的校准载玻片 - Google Patents

用于数字病理学的校准载玻片 Download PDF

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Publication number
CN108474874B
CN108474874B CN201680075868.5A CN201680075868A CN108474874B CN 108474874 B CN108474874 B CN 108474874B CN 201680075868 A CN201680075868 A CN 201680075868A CN 108474874 B CN108474874 B CN 108474874B
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calibration
slide
color
layout
scanning microscope
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CN108474874A (zh
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M·I·博安法
S·M·瓦尔斯特尔
P·什雷斯塔
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • G01N21/278Constitution of standards
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0076Optical details of the image generation arrangements using fluorescence or luminescence
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008Details of detection or image processing, including general computer control
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/34Microscope slides, e.g. mounting specimens on microscope slides
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00Optical elements other than lenses
    • G02B5/008Surface plasmon devices

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Multimedia (AREA)
  • General Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
CN201680075868.5A 2015-12-23 2016-12-23 用于数字病理学的校准载玻片 Active CN108474874B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15202506 2015-12-23
EP15202506.0 2015-12-23
PCT/EP2016/082564 WO2017109175A1 (en) 2015-12-23 2016-12-23 Calibration slide for digital pathology

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CN108474874A CN108474874A (zh) 2018-08-31
CN108474874B true CN108474874B (zh) 2022-07-01

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US (1) US11002667B2 (enExample)
EP (1) EP3394649B1 (enExample)
JP (2) JP7057279B6 (enExample)
CN (1) CN108474874B (enExample)
RU (1) RU2734097C2 (enExample)
WO (1) WO2017109175A1 (enExample)

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CN108431664B (zh) * 2015-12-23 2021-11-02 皇家飞利浦有限公司 荧光校准载片
US10663711B2 (en) 2017-01-04 2020-05-26 Corista, LLC Virtual slide stage (VSS) method for viewing whole slide images
CN108181673A (zh) * 2018-01-02 2018-06-19 苏州大学 超分辨光学显微镜成像载玻片和具有其的光学显微镜
JP7458328B2 (ja) 2018-05-21 2024-03-29 コリスタ・エルエルシー マルチ分解能登録を介したマルチサンプル全体スライド画像処理
WO2020044762A1 (ja) 2018-08-28 2020-03-05 パナソニックIpマネジメント株式会社 センサ基板及びその製造方法
CA3121434A1 (en) 2018-11-29 2020-06-04 La Trobe University Microscopy method and system
EP3887799B1 (en) 2018-11-29 2024-04-24 La Trobe University Automated method of identifying a structure
SG11202105311VA (en) 2018-11-29 2021-06-29 Univ La Trobe Method of identifying a structure
US12313629B2 (en) * 2019-03-20 2025-05-27 Biosquare Inc. Standard material composition for verifying bioanalyzer and standard strip using same
CN113348401A (zh) 2019-08-06 2021-09-03 徕卡生物系统成像股份有限公司 物理校准玻片
CN111521591B (zh) * 2020-05-09 2021-04-16 艾普拜生物科技(苏州)有限公司 用于微滴式数字pcr仪的计数校准装置、制备及使用方法
WO2022047321A1 (en) * 2020-08-31 2022-03-03 Applied Materials, Inc. Method of calibration of mfish using slides
KR20220157196A (ko) 2021-05-20 2022-11-29 삼성전자주식회사 이미지 처리 방법 및 그 전자 장치
US12259326B2 (en) 2021-10-20 2025-03-25 Arizona Board Of Regents On Behalf Of Arizona State University Dry fluorescence calibration technique
DE102022115989A1 (de) 2022-06-27 2023-12-28 Carl Zeiss Microscopy Gmbh Mikroskopiesystem und Verfahren zur Farbkorrektur von Mikroskopbildern
KR102769819B1 (ko) * 2023-07-12 2025-02-20 충북대학교 산학협력단 메타물질 보조 국소화 현미경용 슬라이드 글라스 및 이의 제조 방법

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RU2018126781A (ru) 2020-01-23
WO2017109175A1 (en) 2017-06-29
EP3394649A1 (en) 2018-10-31
RU2734097C2 (ru) 2020-10-12
RU2018126781A3 (enExample) 2020-04-27
JP2022066215A (ja) 2022-04-28
US11002667B2 (en) 2021-05-11
CN108474874A (zh) 2018-08-31
JP7057279B2 (ja) 2022-04-19
JP7057279B6 (ja) 2022-06-02
JP2019502942A (ja) 2019-01-31
EP3394649B1 (en) 2022-02-09
US20200264096A1 (en) 2020-08-20

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