CN108452015A - A kind of drug for treating pericarditis - Google Patents

Abstract

The present invention relates to a kind of drugs for treating pericarditis, it is prepared by the raw medicinal material of following weight proportion：6 parts of cassia twig, 9 parts of Poria cocos, 8 parts of lepidium seed（It decocts a drug wrapped）, 8 parts of Radix Codonopsis.Cassia twig, acrid, sweet, warm are used in side；The thoughts of returning home, lung, bladder warp.With sweating expelling pathogenic factors from muscles and skin, the effect of warming meridian, helps yang transforming qi, flat gas that spins, help sharp water medicine with tonneau urine；Poria cocos, it is sweet, light, it puts down, the thoughts of returning home, lung, spleen, kidney channel, clearing damp and promoting diuresis, invigorating the spleen calming heart；Lepidium seed, return lung, bladder warp, removing heat from lung and relieving asthma, line water detumescence；Radix Codonopsis, returns spleen, lung channel, tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.All medicines share, plays warming yang for activating qi-flowing altogether, and the work(of sharp aquation phlegm can accomplish that As the medicine took effect, the symptoms lessened substantially.Clinical trial prompts, and the present invention can safely and effectively be applied to the treatment of pericarditis.

Description

A kind of drug for treating pericarditis

Technical field

The present invention relates to a kind of drugs, and in particular to a kind of Chinese medicine for treating pericarditis.

Background technology

Pericarditis refers to that because of factors such as bacterium, virus, autoimmunity, physics, chemistry acute inflammatory response occurs for pericardium And sepage and pericardiosymphysis, thicken, constriction, calcification chronic diseases become.Clinically mainly there are acute pericarditis and chronic constriction Fibrinous pericarditis.

Clinical manifestation：Patient has the symptoms such as fever, night sweat, cough, pharyngalgia or vomiting, diarrhea.Pericardium oozes out a large amount of hydrops Acute heart tamponade symptom can occur.Patient's pectoralgia, expiratory dyspnea, cyanosis, pale complexion, or even shock.Can also there are ascites, liver The symptoms such as big.

Medicinal material present Research involved in the present invention is as follows：

Cassia twig【Source】This product is the dry twig of canella Chinese cassia tree Cinnamomum cassia Presl.Spring, Xia Erji Harvesting removes defoliation, dries, or slice dries.【It processes】Impurity is removed, is slightly steeped, cleans, moisturizes, shave dries.This product is The section of similar round, the piece of ellipse or irregular shape.Skin zone's rufous, the sometimes visible dotted hole skin in surface or vertical rib line, woody part Yellow-white or light yellowish brown, marrow similar round or are slightly square.【Nature and flavor】Acrid, sweet, warm.【Channel tropism】The thoughts of returning home, lung, bladder warp. 【Major function】Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, the cold warp of blood It closes, joint pain, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.【Usage and dosage】3~9g.【Storage】It sets at shady and cool drying.

Poria cocos【Source】This product is On Polyporaceae Poria cocos Poria cocos（Schw.）The drying bacterium of Wolf Core.It is excavated more than 7~September, removes silt after digging out, after banking up " sweating ", spread out and dry in the air to dry tack free, then " sweating ", repeatedly It after scattering and disappearing for several times to existing wrinkle, the big portion of internal moisture, dries in the shade, referred to as " Poria cocos "；Or fresh Poria cocos is pressed into different parts cutting, it is cloudy It is dry, it is referred to as " fuling peel " and " Poria cocos block ".【It processes】Take Poria cocos, impregnate, clean, slightly steamed after profit, cut in time skin and Block cuts sheet, dries.【Nature and flavor】It is sweet, light, it puts down.【Channel tropism】The thoughts of returning home, lung, spleen, kidney channel.【Major function】Clearing damp and promoting diuresis is good for Spleen calming heart.For oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.【Usage and dosage】 9 ~15g.【Storage】Dry place is set, it is moisture-proof.

Lepidium seed【Source】This product is crucifer Lepidium apetalum Lepidium apetalum Willd. or broadcasts ma Wormwood artemisia Descurainia sophia（L.）The dry mature seed of Webb ex prantl.The former practises title " lepidii,semen ", the latter It practises and claims " descurainiae,semen ".Plant is tapped when summer fruit maturation, is dried, seed is rubbed, removes impurity.【Nature and flavor】It is pungent, bitter, greatly It is cold.【Channel tropism】Return lung, bladder warp.【Major function】Removing heat from lung and relieving asthma, line water detumescence.For sputum stop up lung, dyspnea and cough with excessive sputum, chest side of body Turgor must not lie down, chest and abdomen oedema, difficult urination；Cor pulmonale oedema.【Usage and dosage】3~9g decocts a drug wrapped.【Storage】 Set dry place.

Radix Codonopsis【Source】This product is Campanulaceae Radix Codonopsis Codonopsis pilosula（Franch.） Nannf.、 Codonopsis pilosula var. modesta（RADIX CODONOPSIS PILOSULAE from Northwest of China）Codonopsis pilosula Nannf. var. modesta （Nannf.）L. T. Shen or The dry root of radix codonpsis tangshen Codonopsis tangshen Oliv..Autumn excavates, and cleans, dries.【It processes】Impurity is removed, is washed Only, it moisturizes, cuts sheet, it is dry.【Nature and flavor】Sweet and neutral.【Channel tropism】Returns spleen, lung channel.【Major function】Tonifying middle-Jiao and Qi, invigorating the spleen benefit Lung.For spleen and lung weakness, shortness of breath and palpitation, anorexia and loose stool, virtual asthma cough, Heat Diabetes.【Usage and dosage】8~30g.【Pay attention to】 It should not be with black false hellebore with use.【Storage】It sets at aeration-drying.It is mothproof.

Invention content

The present invention is intended to provide a kind of drug for treating pericarditis is reached by selecting suitable medicinal material and its proportioning To the purpose safely and effectively applied to pericarditis treatment.

In order to achieve the above object, the present invention uses following technical scheme：

A kind of drug for treating pericarditis, which is characterized in that it is prepared by the raw medicinal material of following weight proportion： 6 parts of cassia twig, 9 parts of Poria cocos, 8 parts of lepidium seed, 8 parts of Radix Codonopsis.

Inventor is according to the Couple herbs having the deep influence of a scholarly family, it is believed that：Pericarditis belongs to the scope of Chinese medicine " phlegm and retained fluid ", " obstruction of qi in the chest ", Etiology and pathogenesis：Internal wetness hyperactivity, deficiency of yang gasification is powerless, and water pathogen attacking heart penetrates lung, and aqueous assembles pericardium and falls ill.Principle of reatment is Wen Yang Change gas Li Shui.Cassia twig, acrid, sweet, warm are used in side；The thoughts of returning home, lung, bladder warp.With sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, The effect of flat gas that spins, helps sharp water medicine with tonneau urine；Poria cocos, it is sweet, light, it puts down, the thoughts of returning home, lung, spleen, kidney channel, clearing damp and promoting diuresis, invigorating the spleen Calming heart；Lepidium seed, return lung, bladder warp, removing heat from lung and relieving asthma, line water detumescence；Radix Codonopsis, returns spleen, lung channel, tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.It is all Medicine shares, and plays warming yang for activating qi-flowing altogether, and the work(of sharp aquation phlegm can accomplish that As the medicine took effect, the symptoms lessened substantially.

The beneficial effects of the present invention will now be described with reference to clinical experimental data：

1, general information

Inventor selects patients with pericarditis 76 altogether during 2 months in December, 2013 in 2010, is randomly divided into control group and controls Treatment group, every group each 38.Male 22 in control group, women 16 is age 18-58 Sui, 34 years old average, and the course of disease is 1 month -6 A month, palpitaition 45,65 uncomfortable in chest；Male 24 in treatment group, women 14 is age 19-57 Sui, 35 years old average, the course of disease 1 - 6 months a month, palpitaition 49,67 uncomfortable in chest, significant difference was not present in two groups of genders, age and the course of disease, is comparable.

1.1 inclusion criteria

（1）X-ray inspection：Heart shadow increases to both sides when hydrops amount is more than 300ml, and septum cordis angle becomes at an acute angle.Heart when more than 1000ml Shadow is in flask shape, and different with position.Heartbeat weakens or disappears.

（2）Electrocardiogram：When dry pericarditis, each lead（Except aVR）, ST sections are raised, and are back on equipotential line after a few days, T popins are smooth or are inverted.QRS complex is in low-voltage when pericardium has sepage；

（3）Echocardiograph：There is liquefaction dark space in display cavum pericardiale.

1.2 exclusion criteria

（1）The elderly is with multiple complications such as severe cardiac, lung diseases；

（2）Patient with serious multiple organ failure.

2, research method

2.1 therapy

The present invention takes according to decoction made from specific embodiment 1 in treatment group, is taken three times in the morning, afternoon and evening per bu.

Control group gives isoniazid+rifampin, is taken according to its specification.

Two groups are treated 1 month.

Diet is taken good care of oneself：Light, easy to digest, less salt, low fat, limitation intake albumen quality, edible protein is with animal protein Based on, while to lie up, avoid overexercise.

2.2 statistical method

Data are handled using SPSS18.0 statistics softwares.

3, treatment results

3.1 criterion of therapeutical effect

Recovery from illness：Symptom is completely disappeared with sign or is disappeared substantially；Effectively：Symptom or sign have clear improvement；In vain：Symptom with Sign is unchanged or aggravates.Total effective rate=(cure+effective+effectively) ÷ total number of cases × 100%.

3.2 two groups of curative effects

In 38 patients of control group, 5, effective 26, invalid 7 are cured；In treatment group, healing 11, effective 25, Invalid 2.The cure rate of control group is 13.2%, and the cure rate for the treatment of group is 28.9%, and two groups are compared, and there are significant systems Meter learns difference, P<0.05；The total effective rate of control group is 81.6%, and the total effective rate for the treatment of group is 94.7%, and two groups poor It is different notable, P<0.05.

As it can be seen that drug produced by the present invention can safely and effectively treat pericarditis, there is preferable medicine promotional value.

Specific implementation mode

In order to better understand with the implementation present invention, further illustrated the present invention with reference to specific embodiment.

Embodiment 1

It weighs：6 grams of cassia twig, 9 grams of Poria cocos, 8 grams of lepidium seed（It decocts a drug wrapped）, 8 grams of Radix Codonopsis；Add 8 times of amount water, decocts 1.5 hours, filtering； Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate is concentrated into 120 to get decocting for one day dosage of normal adult is met Agent.

For treating pericarditis.It is oral, it is taken three times in the morning, afternoon and evening per bu.

Embodiment 2

It weighs：6 grams of cassia twig, 9 grams of Poria cocos, 8 grams of lepidium seed（It decocts a drug wrapped）, 8 grams of Radix Codonopsis；Add 10 times of amount water, decocts 2 hours, filtering；Filter Slag adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate concentrates, dry, packs to get one day dosage of normal adult is met Powder.

For treating pericarditis.It is oral, daily once.

Embodiment 3

It weighs：6 grams of cassia twig, 9 grams of Poria cocos, 8 grams of lepidium seed（It decocts a drug wrapped）, 8 grams of Radix Codonopsis；Add 6 times of amount water, decocts 3 times, decoct 1 every time Hour, merge decoction liquor, concentrates, it is dry, capsule shells are packed into get the capsule of one day dosage of normal adult is met.

For treating pericarditis.It is oral, it is taken twice sooner or later per bu.

Claims (1)

1. a kind of for treating the drug of pericarditis, which is characterized in that it be prepared by the raw medicinal material of following weight proportion and At：6 parts of cassia twig, 9 parts of Poria cocos, 8 parts of lepidium seed, 8 parts of Radix Codonopsis.