CN109646488A - It is a kind of for treating the drug of pericarditis - Google Patents

Abstract

The present invention relates to a kind of for treating the drug of pericarditis, it is prepared by the raw medicinal material of following weight proportion: 6 parts of ramulus cinnamomi, 9 parts of Poria cocos, 8 parts of lepidium seed (decocting a drug wrapped), 8 parts of Radix Codonopsis.Ramulus cinnamomi, acrid, sweet, warm are used in side；Return heart, lung, bladder meridian.With sweating expelling pathogenic factors from muscles and skin, the effect of warming meridian, help yang gas, flat and gas, help sharp water medicine with tonneau urine；Poria cocos, it is sweet, light, it puts down, return heart, lung, spleen, kidney channel, clearing damp and promoting diuresis, invigorating the spleen calming heart；Lepidium seed, return lung, bladder meridian, removing heat from lung and relieving asthma, line water detumescence；Radix Codonopsis, returns spleen, lung channel, tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.All medicines share, plays warming yang for activating qi-flowing altogether, and the function of sharp aquation phlegm can accomplish that As the medicine took effect, the symptoms lessened substantially.Clinical trial prompt, the present invention can safely and effectively be applied to the treatment of pericarditis.

Description

It is a kind of for treating the drug of pericarditis

Technical field

The present invention relates to a kind of drugs, and in particular to a kind of for treating the Chinese medicine of pericarditis.

Background technique

Pericarditis refers to that because of factors such as bacterium, virus, autoimmunity, physics, chemistry acute inflammatory response occurs for pericardium And sepage and pericardiosymphysis, thicken, constriction, calcification chronic diseases become.Clinically mainly there are acute pericarditis and chronic constriction Fibrinous pericarditis.

Clinical manifestation: patient has the symptoms such as fever, night sweat, cough, pharyngalgia or vomiting, diarrhea.Pericardium oozes out a large amount of hydrops Acute heart tamponade symptom can occur.Patient's pectoralgia, expiratory dyspnea, cyanosis, pale complexion, or even shock.Can also there are ascites, liver The symptoms such as big.

Medicinal material present Research involved in the present invention is as follows:

Ramulus cinnamomi [source] this product is the dry twig of lauraceae plant cortex cinnamomi Cinnamomum cassia Presl.Spring, Xia Erji Harvesting removes defoliation, dries, or slice dries.[processing] removes impurity, slightly steeps, and cleans, moisturizes, shave dries.This product is The section of similar round, the piece of ellipse or irregular shape.Skin zone's rufous, the sometimes visible dotted hole skin in surface or vertical rib line, woody part Yellow-white or light yellowish brown, marrow similar round or are slightly square.[nature and flavor] acrid, sweet, warm.[channel tropism] return heart, lung, bladder meridian. [major function] sweating expelling pathogenic factors from muscles and skin, warming meridian, help yang gas, flat and gas.For anemofrigid cold, coldness and pain in the epigastrium, the cold warp of blood It closes, arthralgia, phlegm retention, oedema, palpitaition, renal mass.[usage and dosage] 3~9g.[storage] is set at shady and cool drying.

Poria cocos [source] this product is the drying bacterium of polyporaceae fungus Poria cocos (Schw.) Wolf Core.It is excavated more than 7~September, removes silt after digging out, after banking up " sweating ", spread out and dry in the air to dry tack free, then " sweating ", repeatedly It after scattering and disappearing for several times to existing wrinkle, the big portion of internal moisture, dries in the shade, referred to as " Poria cocos "；Or fresh Poria cocos is pressed into different parts cutting, yin It is dry, it is referred to as " fuling peel " and " Poria cocos block ".[processing] takes Poria cocos, impregnates, and cleans, slightly steams after profit, cut in time skin and Block cuts sheet, dries.[nature and flavor] are sweet, light, put down.[channel tropism] return heart, lung, spleen, kidney channel.[major function] clearing damp and promoting diuresis is good for Spleen calming heart.For edema and little urine, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.[usage and dosage] 9 ~15g.[storage] sets dry place, moisture-proof.

Lepidium seed [source] this product is crucifer Lepidium apetalum Lepidium apetalum Willd. or broadcasts ma The dry mature seed of wormwood artemisia Descurainia sophia (L.) Webb ex prantl.The former practises title " lepidii,semen ", the latter It practises and claims " descurainiae,semen ".Plant is tapped when summer fruit maturation, is dried, seed is rubbed, removes impurity.[nature and flavor] are pungent, bitter, greatly It is cold.[channel tropism] return lung, bladder meridian.[major function] removing heat from lung and relieving asthma, line water detumescence.For sputum stop up lung, dyspnea and cough with excessive sputum, chest side of body Turgor must not lie down, chest and abdomen oedema, difficult urination；Cor pulmonale oedema.[usage and dosage] 3~9g, decocts a drug wrapped.[storage] Set dry place.

Radix Codonopsis [source] this product be Campanulaceae Radix Codonopsis Codonopsis pilosula (Franch.) Nannf., Codonopsis pilosula var. modesta (RADIX CODONOPSIS PILOSULAE from Northwest of China) Codonopsis pilosula Nannf. var. modesta (Nannf.) L. T. Shen or The dry root of radix codonpsis tangshen Codonopsis tangshen Oliv..Autumn excavation, cleans, dries.[processing] removes impurity, washes Only, it moisturizes, cuts sheet, it is dry.[nature and flavor] sweet and neutral.[channel tropism] returns spleen, lung channel.[major function] tonifying middle-Jiao and Qi, invigorating the spleen benefit Lung.For spleen and lung weakness, shortness of breath and palpitation, anorexia and loose stool, virtual asthma cough, Heat Diabetes.[usage and dosage] 8~30g.[attention] It should not be with black false hellebore with use.[storage] is set at aeration-drying.It is mothproof.

Summary of the invention

The present invention is intended to provide it is a kind of for treating the drug of pericarditis, by selecting suitable medicinal material and its proportion, reach To the purpose safely and effectively applied to pericarditis treatment.

In order to achieve the above object, the invention adopts the following technical scheme:

It is a kind of for treating the drug of pericarditis, which is characterized in that it is prepared by the raw medicinal material of following weight proportion: 6 parts of ramulus cinnamomi, 9 parts of Poria cocos, 8 parts of lepidium seed, 8 parts of Radix Codonopsis.

Inventor is according to the Couple herbs having the deep influence of a scholarly family, it is believed that: pericarditis belongs to the scope of Chinese medicine " phlegm retention ", " thoracic obstruction ", Etiology and pathogenesis: internal wetness hyperactivity, deficiency of yang gasification is powerless, and water pathogen attacking heart penetrates lung, and aqueous assembles pericardium and falls ill.Principle of reatment is Wen Yang Change gas Li Shui.Ramulus cinnamomi, acrid, sweet, warm are used in side；Return heart, lung, bladder meridian.With sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, The effect of flat gas that spins, helps sharp water medicine with tonneau urine；Poria cocos, it is sweet, light, it puts down, return heart, lung, spleen, kidney channel, clearing damp and promoting diuresis, invigorating the spleen Calming heart；Lepidium seed, return lung, bladder meridian, removing heat from lung and relieving asthma, line water detumescence；Radix Codonopsis, returns spleen, lung channel, tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.It is all Medicine shares, and plays warming yang for activating qi-flowing altogether, and the function of sharp aquation phlegm can accomplish that As the medicine took effect, the symptoms lessened substantially.

The beneficial effects of the present invention will now be described with reference to clinical experimental data:

1, general information

Inventor selects patients with pericarditis 76 during 2 months in December, 2013 in 2010 altogether, is randomly divided into control group and controls Treatment group, every group each 38.Male 22 in control group, women 16, the age 18-58 years old, 34 years old average, the course of disease is 1 month -6 A month, palpitaition 45,65 uncomfortable in chest；Male 24 in treatment group, women 14, the age 19-57 years old, 35 years old average, the course of disease 1 - 6 months a month, palpitaition 49,67 uncomfortable in chest, statistical difference was not present in two groups of genders, age and the course of disease, was comparable.

1.1 are included in standard

(1) x-ray inspection: hydrops amount is more than that 300ml Shi Xinying increases to two sides, and septum cordis angle becomes acute angle.Heart when more than 1000ml Shadow is in flask shape, and different with position.Heartbeat weakens or disappears.

(2) electrocardiogram: when dry pericarditis, each lead (except aVR), ST sections are raised, and are back on equipotential line after a few days, T popin is smooth or is inverted.QRS complex is in low-voltage when pericardium has sepage；

(3) Echocardiograph: there is liquefaction dark space in display cavum pericardiale.

1.2 exclusion criteria

(1) the elderly is with the multiple complications such as severe cardiac, lung disease；

(2) with the patient of serious multiple organ failure.

2, research method

2.1 treatment method

The present invention takes according to decoction made from specific embodiment 1 in treatment group, and every bu is taken three times in the morning, afternoon and evening.

Control group gives isoniazid+rifampin, takes according to its specification.

Two groups are treated 1 month.

Diet is taken good care of oneself: light, easy to digest, less salt, low fat, limitation intake albumen quality, edible protein is with animal protein Based on, while to lie up, avoid overexercise.

2.2 statistical method

Data are handled using SPSS18.0 statistics software.

3, treatment results

3.1 criterion of therapeutical effect

Recovery from illness: symptom is completely disappeared with sign or is disappeared substantially；Effective: symptom or sign have clear improvement；It is invalid: symptom with Sign is unchanged or aggravates.Total effective rate=(cure+effective+effectively) ÷ total number of cases × 100%.

3.2 two groups of curative effects

In 38 patients of control group, 5, effective 26, invalid 7 are cured；In treatment group, healing 11, effective 25, Invalid 2.The cure rate of control group is 13.2%, and the cure rate for the treatment of group is 28.9%, and two groups are compared, and there are significant systems Meter learns difference, P < 0.05；The total effective rate of control group is 81.6%, and the total effective rate for the treatment of group is 94.7%, and two groups poor It is different significant, P < 0.05.

As it can be seen that drug produced by the present invention can safely and effectively treat pericarditis, there is preferable medicine promotional value.

Specific embodiment

In order to better understand and implement the present invention, the present invention is further illustrated combined with specific embodiments below.

Embodiment 1

It weighs: 6 grams of ramulus cinnamomi, 9 grams of Poria cocos, 8 grams of lepidium seed (decocting a drug wrapped), 8 grams of Radix Codonopsis；Add 8 times of amount water, decocts 1.5 hours, filtering； Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate is concentrated into 120 to get decocting for one day dosage of normal adult is met Agent.

For treating pericarditis.Oral, every bu is taken three times in the morning, afternoon and evening.

Embodiment 2

It weighs: 6 grams of ramulus cinnamomi, 9 grams of Poria cocos, 8 grams of lepidium seed (decocting a drug wrapped), 8 grams of Radix Codonopsis；Add 10 times of amount water, decocts 2 hours, filtering；Filter Slag adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate is concentrated, dry, packs to get one day dosage of normal adult is met Powder.

For treating pericarditis.It is oral, daily once.

Embodiment 3

It weighs: 6 grams of ramulus cinnamomi, 9 grams of Poria cocos, 8 grams of lepidium seed (decocting a drug wrapped), 8 grams of Radix Codonopsis；Add 6 times of amount water, decocts 3 times, decoct 1 every time Hour, merge decoction liquor, is concentrated, it is dry, capsule shells are packed into get the capsule for meeting one day dosage of normal adult.

For treating pericarditis.Oral, every bu is taken twice sooner or later.

Claims (1)

1. a kind of for treating the drug of pericarditis, which is characterized in that it be by following weight proportion raw medicinal material preparation and At: 6 parts of ramulus cinnamomi, 9 parts of Poria cocos, 8 parts of lepidium seed, 8 parts of Radix Codonopsis.