CN108450475A - A kind of mosquito-repellent - Google Patents
A kind of mosquito-repellent Download PDFInfo
- Publication number
- CN108450475A CN108450475A CN201711012924.3A CN201711012924A CN108450475A CN 108450475 A CN108450475 A CN 108450475A CN 201711012924 A CN201711012924 A CN 201711012924A CN 108450475 A CN108450475 A CN 108450475A
- Authority
- CN
- China
- Prior art keywords
- mosquito
- repellent
- eucalyptalsa
- phytosterol
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N45/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds having three or more carbocyclic rings condensed among themselves, at least one ring not being a six-membered ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
Abstract
The invention discloses a kind of mosquito-repellent, active ingredient includes phytosterol and EucalyptalsA, and active ingredient accounts for 1-the 20% of gross mass, and surplus is water.The mass ratio of the phytosterol and EucalyptalsA is 1:40‑40:1.Inventive formulation is natural active matter, hypotoxicity, and safety and environmental protection just has certain synergy repellent effect by phytosterol and EucalyptalsA.
Description
Technical field
The present invention relates to a kind of mosquito-repellents.
Background technology
Mosquito is one of four pests, and is the portable object of virus.With the development of society, human living standard's constantly carries
Height, people are also being continuously increased the consciousness of health and self-protection, and various mosquito repellent products come into being in succession.Currently, summer
The most commonly used mosquito repellent articles for use of middle people are mosquito-repellent incenses but the main effective ingredient of most of mosquito-repellent incenses is pyrethrin insecticide, this
Class compound is highly effective in terms of controlling mosquito harm, but also very high to the toxicity of the mankind and can remain in biology for a long time
In vivo, there is carcinogenesis.The case for making propagation medium by mosquito in recent years is more and more, and mosquito control has become domestic and international insect
Worker's issues that need special attention, while with the rapid development of mosquito drug resistance, drug level being forced to improve again and again, this is not only
Cost is improved, and be easy to cause serious environmental pollution, violates continuable development principle.In the case, it develops or selects
Anophelifuge activity ingredient appropriate, and common culicifuge system is optimized, make it in repelling effect, the influence etc. to environment
Aspect is with good general performance obviously with very real meaning.With the improvement of people's awareness of environmental protection, environment
The research and development of friendly, high-efficiency low-toxicity and the mosquito-repellent of low resistance is particularly important.Plant-originated repellent derives from
Natural plants, it is environmentally friendly, it is degradable, become the emphasis of developmental research, the searching for plant source mosquito repellant,
People have done a large amount of experimental work, but still inadequate on the whole, and people are not also very clear to the repellent mechanism of mosquito
Chu, therefore also a large amount of need of work researcher is made joint efforts and is completed.
Invention content
It is a kind of completely new in view of the above existing problems in the prior art, the present invention provides a kind of mosquito-repellent is utilized
Plant source mosquito repellant has good repellent effect, and nontoxic, safety and environmental protection.
A kind of mosquito-repellent, active ingredient include phytosterol and EucalyptalsA, and active ingredient accounts for gross mass
1-20%, surplus is water.
The mass ratio of the phytosterol and EucalyptalsA is 1:40-40:1.
Inventive formulation is natural active matter, hypotoxicity, safety and environmental protection, by phytosterol and
EucalyptalsA just has certain synergy mosquito repelling effect, and especially phytosterol and EucalyptalsA is in 25-30:1
Section there is surprising repellent effect, the repellent time reaches 12h or more.
Specific implementation mode
The eucalyptalsA that the present invention mentions, structural formula are as follows：
It is that the new skeleton with 3,5-, bis- formyls-isopentyl phloroglucin-benzidine is isolated from from eucalyptus fruit,
Preparation method can be with bibliography：
EucalyptalsA−CwithaNewSkeletonIsolatedfromEucalyptusglobulus.
Org.Lett.,2007,9(26),pp5549–5552。
Phytosterol CAS：83-46-5.
A kind of mosquito-repellent, active ingredient include phytosterol and EucalyptalsA, and active ingredient accounts for gross mass
1-20%, surplus is water.
The mass ratio of the phytosterol and EucalyptalsA is 1:40-40:1.
Laboratory repellent experiment effect evaluation
Attack is tested：
It is put into 600 test worms in the mosquito cage that length × height × width is 20 × 20 × 30cm, half male and half female, testing crew is sudden and violent in arm
Reveal 4cm × 4cm skins, rest part tightly covers.By arm stretch into mosquito cage place certain time (aedes albopictus 3min,
Culex pipiens pallens is 5min), record comes to stop the test worm number fallen, and aedes albopictus stops falling light color library in more than 30,5 minutes in 3min
Mosquito stops falling more than 20, judges that the testing crew and this cage mosquito can be used for repellency test.
Repellency test：
The testing crew for selecting attack qualification respectively draws the skin area of 5cm × 5cm on its both hands arm, wherein an arm
For attack experimental control, another hand is smeared repellant to be measured, exposure 4cm therein by the dose uniformity of 1.5mg/cm2
× 4cm skins.Arm is stretched into the mosquito cage of attack qualification and (when attack is less than requiring, is stopped by 2h after smearing repellant
Human body coating is tested, this experiment is invalid), every time 3 minutes (aedes albopictus) or 5 minutes (Culex pipiens pallens), whether there is or not mosquitoes for observation
Come to suck blood, test is primary per hour later, observes the situation of biting of mosquito, and 1 observation there are 2 bite by mosquitos or adds up have 3
Or more bite by mosquitos be failure.
Mosquito used in laboratory is aedes albopictus.
Active ingredient a concentration of 3%, remaining is water:
Experiment finds that single phytosterol and EucalyptalsA have certain mosquito repelling effect, but when effective repellent
Between not enough often, and the two mixing match improves, but improvement effect is not notable, about improves 15-20% or so, but
Its phytosterol and EucalyptalsA are in 15-50:1 section has surprising repellent effect, it is seen that this ratio section
Under, mixed liquor repellent activity greatly enhances, and has significant mosquito repelling effect, the mosquito repelling time is increased to 12 hours
More than, it is seen that the two has obviously synergy in this section, can effectively reduce the usage amount of mixture.
Claims (3)
1. a kind of mosquito-repellent, which is characterized in that active ingredient includes phytosterol and EucalyptalsA, described
EucalyptalsA structural formulas are as follows：
。
2. a kind of mosquito-repellent according to claim 1, which is characterized in that the active ingredient accounts for gross mass
1—20%。
3. a kind of mosquito-repellent according to claim 1, which is characterized in that the phytosterol and
EucalyptalsA mass ratioes are 1:40-40:1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711012924.3A CN108450475A (en) | 2017-10-26 | 2017-10-26 | A kind of mosquito-repellent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711012924.3A CN108450475A (en) | 2017-10-26 | 2017-10-26 | A kind of mosquito-repellent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108450475A true CN108450475A (en) | 2018-08-28 |
Family
ID=63221128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711012924.3A Pending CN108450475A (en) | 2017-10-26 | 2017-10-26 | A kind of mosquito-repellent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108450475A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109758450A (en) * | 2019-03-06 | 2019-05-17 | 天津医科大学 | A kind of antineoplastic novel compound, and its preparation method and application |
| CN115968876A (en) * | 2023-01-12 | 2023-04-18 | 中山榄菊日化实业有限公司 | Long-acting insecticidal ultra-low volume liquid and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104488983A (en) * | 2014-12-13 | 2015-04-08 | 广西科技大学 | Application of eucalyptus globulus labill leaf essential oil |
| CN107996622A (en) * | 2018-01-25 | 2018-05-08 | 陕西葆琛生物科技有限公司 | A kind of mosquito-repellent containing plants essential oil |
-
2017
- 2017-10-26 CN CN201711012924.3A patent/CN108450475A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104488983A (en) * | 2014-12-13 | 2015-04-08 | 广西科技大学 | Application of eucalyptus globulus labill leaf essential oil |
| CN107996622A (en) * | 2018-01-25 | 2018-05-08 | 陕西葆琛生物科技有限公司 | A kind of mosquito-repellent containing plants essential oil |
Non-Patent Citations (5)
| Title |
|---|
| M.H.SALARI ET AL: "Antibacterial effects of Eucalyptus globulus leaf extract on pathogenic bacteria isolated from specimens of patients with respiratory tract disorders", 《CLINICAL MICROBIOLOGY AND INFECTION》 * |
| 刘辉 等: "9种植物精油对白蚊伊蚊驱避活性的研究", 《中华卫生杀虫药械》 * |
| 周璐: "蛇莓杀蚊幼活性成分进一步分离", 《中国优秀硕士学位论文全文数据库，农业科技辑》 * |
| 李伟: "桉属植物中间苯三酚衍生物的研究进展", 《中草药》 * |
| 黄继光 等: "Insecticidal activities and active ingredients of Cacalia tangutica against Musca domestica and Aedes albopictus", 《昆虫学报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109758450A (en) * | 2019-03-06 | 2019-05-17 | 天津医科大学 | A kind of antineoplastic novel compound, and its preparation method and application |
| CN115968876A (en) * | 2023-01-12 | 2023-04-18 | 中山榄菊日化实业有限公司 | Long-acting insecticidal ultra-low volume liquid and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180828 |
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| WD01 | Invention patent application deemed withdrawn after publication |