CN108434365A - A kind of serial medicine and preparation method thereof for treating chronic pelvic pain - Google Patents

A kind of serial medicine and preparation method thereof for treating chronic pelvic pain Download PDF

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Publication number
CN108434365A
CN108434365A CN201810555830.9A CN201810555830A CN108434365A CN 108434365 A CN108434365 A CN 108434365A CN 201810555830 A CN201810555830 A CN 201810555830A CN 108434365 A CN108434365 A CN 108434365A
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China
Prior art keywords
parts
abdomen
lump
disappears
pain
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CN201810555830.9A
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Inventor
翟凤霞
胡玉荃
刘蔚霞
马素娟
李焱
郭淼
张娥
李玲玲
贺燕
周立
张维怡
郑雅萍
代文华
常瑛瑛
王庆阁
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First Affiliated Hospital of Henan University of TCM
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First Affiliated Hospital of Henan University of TCM
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Priority to CN201810555830.9A priority Critical patent/CN108434365A/en
Publication of CN108434365A publication Critical patent/CN108434365A/en
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/586Turtles; Tortoises, e.g. terrapins
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Abstract

The invention discloses a kind of serial medicine and preparation method for treating chronic pelvic pain, serial medicine includes relieving pain of dysmenorrhea side, disappear lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears;Relieving pain of dysmenorrhea is made of the bulk pharmaceutical chemicals of following parts by weight:Peach kernel, ground bettle, motherwort, corydalis tuber, the root bark of tree peony, radix ampelopsis, oldenlandia diffusa, Cortex Eucommiae, Morinda officinalis, Radix Astragali and honey-fried licorice root;The lump in the abdomen analgesia side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:Radix Codonopsis, the root of three-nerved spicebush, Radix Salviae Miltiorrhizae, turtle shell, Cortex Eucommiae, Morinda officinalis, honeysuckle, Fructus Forsythiae, field pennycress, fries coix seed, the Chinese bulbul and honey-fried licorice root at Radix Astragali;The lump in the abdomen bowel lavage side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:Kelp, seaweed, edible tulip, radix paeoniae rubra, Sargent gloryvine, bittersweet, field pennycress, the coptis and the sophora bud.The advantages that serial prescription of the present invention is combined according to the physical feature of women after intermenstrual period and menstruation, while by for oral administration and external application, and efficacy result is notable, and uneasy to recur, non-evident effect, patient is easy to receive, therapeutic process no pain.

Description

A kind of serial medicine and preparation method thereof for treating chronic pelvic pain
Technical field
The invention belongs to technical field of Chinese medicine, more particularly to a kind of serial medicine for treating chronic pelvic pain and its preparation side Method.
Background technology
Currently, the definition of the chronic pelvic pain (CPP) of most of research approvals is aperiodicity pelvic pain, and continue 6 Month or more, it generates dysfunction or needs removal or operative treatment.It is said on stricti jurise, chronic pelvic pain is one group of syndrome, Its cause of disease is complicated, and patient is mostly Women of Childbearing Age, and incidence is up to 15%, and majority can also generate physiology with organic disease Dysfunction and mental symptom.Wherein pelvic inflammatory disease causes the incidence of chronic pelvic pain up to 20.85%.In China, Pelvic inflammatory disease belongs to common disease, frequently-occurring disease in married woman.If pelvic inflammatory disease fails in time, correctly to treat, then It is easy to develop into sequelae of pelvic inflammatory disease, and it is main that wherein about 1/10th patient, which is with chronic pelvic pain, What symptom was seen a doctor, sequelae of pelvic inflammatory disease is to cause the most common reason of gynecologic chronic pelvic pain.
Western medicine has viewpoint to think, sequelae of pelvic inflammatory disease is commonly present pelvic cavity blood circulation disorder, shows as uterus Other hyperblastosis, adhesion, or even form inflammatory mass.And why it is difficult to effect a radical cure, and is because pathogenic bacteria are in hyperplasia and adhesion Connective tissue in, drug is difficult to deeply wherein affect the treatment, and germ is active again and keep the state of an illness anti-when hypoimmunity Recurrence is made.The key for treating this disease is answered promoting blood circulation and removing blood stasis, improves pelvic cavity blood circulation, the tissue of hyperplasia adhesion is made to loosen dissipation, this Sample drug could be reached to play a role in sick institute, and this is exactly characteristic and the advantage place of Chinese traditional treatment.
Although chronic pelvic pain not ached with waist sacrum, do not endured hardships due to long-term lower abdominal pain falling inflation by threat to life It is tired, while patient seriously affects the physical and mental health and life matter of patient mostly with the Spirit nerve symptoms of disease such as anxiety, suspicious, depressed Amount increases the financial burden of society and family, also exacerbates the unstability of society and family, and the course of disease gets over elder and treats effect Fruit is more bad.Illness rate and recurrence rate increase, are in treatment intractable, the problems such as unsatisfactory curative effect, become the clinical doctor of puzzlement Raw problem.Modern medicine there is no effective therapy certainly, traditional Chinese medicine to become clinical treatment chronic pelvic pain at present The main means of chronic pelvic pain.
Invention content
The present invention is based on the theory of traditional Chinese medical science of " pain then obstructed ", " prolonged illness multiple deficiency and stasis " and " Rong Ze not bitterly " " no pain by smooth breath ", Physiological period, pelvic cavity design feature in combination with women, a kind of serial prescription that treating chronic pelvic pain provided.It is this to control Treating chronic pelvic pain series prescription is mutually tied with external application according to the physical feature of women after intermenstrual period and menstruation, while by for oral administration It closes, obtained this serial prescription.
The present invention is provided and a kind for the treatment of chronic pelvic pain for problems existing in terms of current chronic pelvic pain treatment Serial prescription, this series prescription is three kinds, is specifically divided into relieving pain of dysmenorrhea for oral administration during intermenstrual period the 1-5 days Side, the 6th day menstrual cycle start the lump in the abdomen bowel lavage side that disappears of lump in the abdomen analgesia side and the clean period bowel lavage after 3 days that disappears for oral administration.The series Prescription clinical application efficacy result is notable, uneasy to recur, highly practical, and patient is easy to grasp, and therapeutic process no pain, can Pain is released for numerous chronic pelvic pain patients, is improved the quality of living.
To achieve the goals above, the technical solution that the application uses for:
A kind of serial medicine for treating chronic pelvic pain, including relieving pain of dysmenorrhea side, disappear lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears;
Wherein, the relieving pain of dysmenorrhea is made of the bulk pharmaceutical chemicals of following parts by weight:9~12 parts of peach kernel, 6~10 parts of ground bettle, 25~30 parts of motherwort, 9~12 parts of corydalis tuber, 9~12 parts of the root bark of tree peony, 9~12 parts of radix ampelopsis, 25~30 parts of oldenlandia diffusa, Cortex Eucommiae 3~6 parts of 12~15 parts, 12~15 parts of Morinda officinalis, 12~18 parts of Radix Astragali and honey-fried licorice root;
The lump in the abdomen analgesia side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:10~15 parts of Radix Codonopsis, 18~25 parts of Radix Astragali, the root of three-nerved spicebush 9~12 parts, 15~20 parts of Radix Salviae Miltiorrhizae, 10~15 parts of turtle shell, 12~15 parts of Cortex Eucommiae, 12~18 parts of Morinda officinalis, 25~30 parts of honeysuckle, 10~15 parts of Fructus Forsythiae, fries 6~9 parts of 20~30 parts of coix seed, 15~20 parts of the Chinese bulbul and honey-fried licorice root at 40~50 parts of field pennycress;
The lump in the abdomen bowel lavage side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:12~15 parts of kelp, 12~15 parts of seaweed, mountain are kind 12~15 parts of mushroom, 12~15 parts of radix paeoniae rubra, 15~20 parts of Sargent gloryvine, 25~30 parts of bittersweet, 25~30 parts of field pennycress, the coptis 10~15 10~15 parts of part and the sophora bud.
The preparation method of the serial medicine of this treatment chronic pelvic pain, includes preparation, the lump in the abdomen that the disappears analgesia side of relieving pain of dysmenorrhea side Preparation and the lump in the abdomen bowel lavage side that disappears preparation;
Wherein, the preparation process of the relieving pain of dysmenorrhea side is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite, cold water is used in combination to impregnate 25min~35min, the dosage of cold water For the high drug plane 2cm~3cm of the water surface in marmite;Secondly, it after boiling by intense fire, uses instead and is cooked by slow fire 25min~35min, filter, It obtains first time filter residue and first time concoction is for use;Again, water is added into first time filter residue, is boiled by intense fire, is changed and be cooked by slow fire 15min~25min, filtering, obtains filter residue and second of concoction, wherein second of concoction is for use;Finally, and by second of concoction It is mixed with first time concoction, obtains relieving pain of dysmenorrhea side;
The preparation process of the lump in the abdomen analgesia side that disappears is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite, cold water is used in combination to impregnate 30min~1h, the dosage of cold water is The high drug plane 2cm~3cm of the water surface in marmite;Secondly, it after boiling by intense fire, uses instead and is cooked by slow fire 30min~40min, filter, obtain It is for use to first time filter residue and first time concoction;Again, water is added into first time filter residue, is boiled by intense fire, is changed and be cooked by slow fire 20min ~30min, filtering, obtains filter residue and second of concoction, wherein second of concoction is for use;Finally, and by second of concoction and Concoction mixing, obtains the lump in the abdomen analgesia side that disappears;
The preparation process of the lump in the abdomen bowel lavage side that disappears is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite;Secondly, 30min~1h, the dosage of cold water are impregnated with cold water For the high drug plane 2cm~3cm of the water surface in marmite;Again, it after boiling by intense fire, uses instead and is cooked by slow fire 40min~50min, filter, Obtain the lump in the abdomen bowel lavage side that disappears.
The pharmacological action of each taste bulk pharmaceutical chemicals:
Peach kernel has promoting blood circulation, relaxes bowel, relieving cough and asthma effect.For closed dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, lung carbuncle intestines Carbuncle, injury from falling down, dry constipation of intestines, cough and asthma.
Ground bettle is cold in nature, and taste is salty;It is slightly poisonous, return liver warp, broken stasis of blood blood, continuous muscles and bones.For injured bone, blood stasis closed, disease Lump in the abdomen lump in the abdomen.
Motherwort have promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, it is clearing heat and detoxicating the effect of.For irregular menstruation, dysmenorrhoea Amenorrhea, lochia Not to the utmost, oedema oliguria, sore swollen toxin.
Corydalis tuber cures mainly all pains of trusted subordinate's waist and knee, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury Deng having analgesia, calmness, syngignoscism.
The root bark of tree peony has the central inhibitory actions such as calmness, cooling, antipyretic, analgesia, spasmolysis and antiatherosclerosis, diuresis, resists The effects that ulcer.
Radix ampelopsis has clearing heat and detoxicating, carbuncle that disappears dissipating bind and other effects.
Oldenlandia diffusa enters stomach, large intestine, small intestinl channel, clearing heat and detoxicating, carbuncle that disappears dissipating bind, promoting urination and removing dampness.
Cortex Eucommiae is sweet in flavor, warm-natured.Tonify the liver and kidney, strengthen muscles and bones, coordinating Chong and Conception Vessels, strengthen meridian and miscarriage prevention the effect of.
Morinda officinalis cures mainly impotence and seminal emission, uterus cold infertile, irregular menstruation, few abdomen crymodynia, arthralgia pain due to rheumatism, muscles and bones impotence.
There is Radix Astragali enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial to make With.
Honey-fried licorice root has benefiting qi and nourishing yin, and activate yang multiple arteries and veins therapeutic efficiency.
Radix Codonopsis has the effect of tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.Radix Codonopsis has strengthen immunity, expansion blood vessel, decompression, improvement micro- The effects that cycle, enhancing hematopoiesis function.
The root of three-nerved spicebush is used for promoting qi circulation and relieving pain, warming kidney for dispelling cold.
Radix Salviae Miltiorrhizae is used for chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea warp It closes, sore swell and ache curative.
Turtle shell replenishing the vital essence and removing heat, calming the liver to stop the wind, softening and resolving hard mass.Zhi Laore hectic fever due to yin, wind formation from yin deficiency, malaria with general debility malaria with abdominal mass, Disorder lump in the abdomen Xuan addictions, It is leaked through amenorrhoea, pediatric epilepsy scared.
Honeysuckle is known as clearing heat and detoxicating good medicine.The sweet cold air fragrance of its property, clear heat with drugs of sweet flavour and cold nature is without injuring one's stomach, and fragrance is thoroughly up to again It can eliminating evil.Honeysuckle can dispelling wind-heat, also kind removing summer-heat blood poison is used for various febrile diseases, such as body heat, dermexanthesis, macular eruption, heat toxin sore The diseases such as carbuncle, abscess of throat, equal significant effect.
Fructus Forsythiae has the effect of heat-clearing, removing toxic substances, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine Leaching is closed.
Field pennycress acrid flavour, hardship have clearing heat and detoxicating, removing blood stasis and expelling pus and other effects.
It is cool in nature to fry coix seed, it is sweet in flavor, light, enter spleen, lung, kidney channel, has effects that Li Shui, invigorating the spleen, eliminating impediment, clearing away heat and eliminating pus.
Chinese bulbul bitter, it is cold in nature;Return stomach, large intestine channel.It with clearing heat and detoxicating, removes heat from the blood and relieve diarrhea, the effect of removing dampness and destroying parasites.
Kelp has dissolving phlegm softening hard masses;The effect of profit water detumescence.
Seaweed has the effect of dissolving phlegm softening and resolving hard mass, inducing diuresis for removing edema.
Edible tulip is sweet in flavor, micro-pungent, cool in nature.With clearing heat and detoxicating, carbuncle that disappears dissipating bind and other effects, it is usually used in carbuncle swells serious case of furuncle, scrofula Subcutaneous nodule, snakebite and bugbite, lame lump in the abdomen lump in the abdomen.
Radix paeoniae rubra is bitter, is slightly cold.Return liver warp.There is the effect of clearing heat and cooling blood, promoting blood circulation.
Sargent gloryvine Toxin-Vanquishing disappears carbuncle, promoting blood circulation and removing obstruction in channels, wind dispelling insecticide.Control acute and chronic appendicitis, arthralgia pain due to rheumatism, dysentery characterized by blood in the stool, blood strangury, the moon Through uncomfortable, infantile malnutrition due to digestive disturbances or intestinalparasites, worm pain, injury from falling down.
Bittersweet cures mainly clearing heat and detoxicating.Main abscess of throat;Blurred vision is red;Mastitis;Rib inflammation;Mange;Mange itch.
The coptis has the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating.
Sophora bud cold nature, bitter have effects that relax bowel, blood-stanching and blood-cooling.
Compared with prior art, the beneficial effects of the invention are as follows:
Peach kernel, ground bettle, the root bark of tree peony, motherwort blood circulation and removing stasis in relieving pain of dysmenorrhea side, make the uterus vessels of the uterus stasis of blood it is stagnant must dissipate and smoothly Outer row, " no pain by smooth breath ";" qi and blood obtains Wen Zehang ", therefore with Cortex Eucommiae, Morinda officinalis, corydalis tuber warm kidney warm the womb, regulating qi-flowing for relieving pain;This disease is past With the passing of time toward the course of disease, multiple deficiency and stasis, therefore with Radix Astragali, honey-fried licorice root QI invigorating righting, blood is taken the photograph in promoting circulation of blood again;" stasis of blood easily changes heat long ", therefore with white flower HERBA HEDYOTIS DIFFUSAE, the removing toxic substances of radix ampelopsis clearing heat and promoting diuresis, the anti-latent interior heresy accumulate, which is taken advantage of a weak point in opponent's defence, stages an armed rebellion, and restricts the property of his medicine temperate-dryness, and pharmacological research carries Show that this three tastes medicine has the benefits of antibacterial, anti-inflammatory, analgesia.The life that inducing meastruation to relieve menalgia policy is just opening premenstrual abundance of blood in CHONG meridian, menstrual period blood room Reason feature catches the opportune time of this anti-inflammatory of menstrual period, temperature row living to mend with using, strengthening vital QI to eliminate pathogenic factors is simultaneously according to the principle made the best use of the situation Row, the medicine of fever and chills are assisted altogether, and gas promoting circulation of blood is made to live, and menses pass unimpeded, " logical without pain ".
Blood goes impairment of qi, born of the same parents' door to be closed after, suitable " asking because effecting a permanent cure ".Often recurrent exerbation, protracted course are with the passing of time, weakened body resistance for this disease The domination of pathogen, dampness and heat stasis vessels of the uterus punching of trembling with fear are appointed, not general rule pain, therefore more void, the stasis of blood, wet, hot and see.With Radix Codonopsis, Radix Astragali in the lump in the abdomen that disappears analgesia side It replenishes qi to invigorate the spleen, green blood promoting circulation of blood;Cortex Eucommiae, Morinda officinalis making lumbus stronger and consolidating vital energy, tonifying Chong and Ren channels are strengthened the body resistance to consolidate the constitution;The root of three-nerved spicebush, Radix Salviae Miltiorrhizae compatibility, one enters gas The cold promoting the circulation of qi of dispersion, one enters blood system promoting blood circulation, makes stasis of blood air-dispersing row, blood vessels are unimpeded and pain is stopped;Turtle shell softening and resolving hard mass, the Jiaization that disappears Disorder, It removes obstruction in channels to relieve pain;" unfavorable blood is then water ", fries the invigorating the spleen again of coix seed clearing damp and promoting diuresis, pharmacological research has sedation and analgesia effect;" stasis of blood is changed long Heat ", wonderful clearing heat and detoxicating in the large dosage of field pennycress and blood-breaking row stasis of blood, inducing meastruation to relieve menalgia, honeysuckle, Fructus Forsythiae, the Chinese bulbul are clearing heat and detoxicating, altogether With the heat in the clear stasis of blood, and the property of its medicine temperate-dryness is restricted, pharmacological research has preferable antipyretic and anti-inflammatory sedation;Honey-fried licorice root reconciles All medicines and the toxicity for solving all medicines.Full side's invigorating the spleen is reinforced the kidney, clearing heat and promoting diuresis, qi-regulating Xiao Disorder, simultaneous treatment of principal and subordinate symptoms, after tangent pelvic inflammatory disease Lose the interpretation of the cause, onset and process of an illness essence of disease, and heresy is not stayed in correction, is got rid of evils and is not hindered just, can make it is hot clear it is wet dispel, the logical knot of the stasis of blood dissipates, and is just so incensed that multiple, qi and blood and Suitable, passages through which vital energy circulates is unimpeded and pain disappears certainly.
Clinically in addition to oral traditional Chinese medicine, Chinese medicinal enema retention enema, Chinese medicine, whole body is coordinated mutually to be tied with local treatment It closes, to improve curative effect, shortens the course for the treatment of.The lump in the abdomen that disappears bowel lavage side function clearing heat, detoxicating, dispelling dampness, softening hard masses promoting blood circulation and removing obstruction in channels, dispersing accumulated pathogens to resolve the mass analgesic. Bittersweet, the coptis, field pennycress are clearing heat and detoxicating in side, dampness removing stagnation resolvation;Radix paeoniae rubra, Sargent gloryvine are promoting blood circulation and removing obstruction in channels;Edible tulip, kelp, seaweed are soft Hard mass dissipating and swelling eliminating;The sophora bud bitter drop cool in nature, lets out the heat of blood system and heresy is made to have outlet.
Relieving pain of dysmenorrhea side takes in menstrual period daystart, even served 5 days;The lump in the abdomen analgesia side that disappears starts to take on the 6th day in menstruation, It even served 20 days;The lump in the abdomen bowel lavage side that disappears is starting external application after net 3 days, and when bowel lavage, 37 DEG C or so of fluid temperature, patient takes lateral position, Disposable enemas tube is inserted into anus 25cm~30cm, blows slowly through disposable enemas tube after syringe taking liquid and injects rectum, retains At least 2h is used in conjunction 15 days.The present invention is mutually tied according to the physical feature of women after intermenstrual period and menstruation, while by for oral administration with external application The advantages that conjunction has efficacy result notable, and uneasy to recur, non-evident effect, patient is easy to receive, therapeutic process no pain, And can be that numerous chronic pelvic pain patients release pain, it improves the quality of living.
Specific implementation mode
In order to make the present invention technological means, creation characteristic, achieving the goal is easy to understand with effect, below in conjunction with The technical solution in the present invention is clearly and completely described in specific embodiments of the present invention.
Embodiment 1
A kind of serial medicine for treating chronic pelvic pain, including relieving pain of dysmenorrhea side, disappear lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears;
Wherein, relieving pain of dysmenorrhea is made of the bulk pharmaceutical chemicals of following parts by weight:9 parts of peach kernel, 25 parts of motherwort, prolongs at 6 parts of ground bettle 9 parts of Hu rope, 9 parts of the root bark of tree peony, 9 parts of radix ampelopsis, 25 parts of oldenlandia diffusa, 12 parts of Cortex Eucommiae, 12 parts of Morinda officinalis, 12 parts of Radix Astragali and honey-fried licorice root 3 Part;
The lump in the abdomen analgesia side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:10 parts of Radix Codonopsis, 18 parts of Radix Astragali, 9 parts of the root of three-nerved spicebush, Radix Salviae Miltiorrhizae 15 Part, 10 parts of turtle shell, 12 parts of Cortex Eucommiae, 12 parts of Morinda officinalis, 25 parts of honeysuckle, 10 parts of Fructus Forsythiae, 40 parts of field pennycress, fry 20 parts of coix seed, 6 parts of 15 parts of the Chinese bulbul and honey-fried licorice root;
The lump in the abdomen bowel lavage side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:12 parts of kelp, 12 parts of seaweed, 12 parts of edible tulip, radix paeoniae rubra 10 parts of 12 parts, 15 parts of Sargent gloryvine, 25 parts of bittersweet, 25 parts of field pennycress, 10 parts of the coptis and the sophora bud.
Embodiment 2
A kind of serial medicine for treating chronic pelvic pain, including relieving pain of dysmenorrhea side, disappear lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears;
Wherein, relieving pain of dysmenorrhea is made of the bulk pharmaceutical chemicals of following parts by weight:10 parts of peach kernel, 8 parts of ground bettle, 27 parts of motherwort, 10 parts of corydalis tuber, 10 parts of the root bark of tree peony, 10 parts of radix ampelopsis, 27 parts of oldenlandia diffusa, 13 parts of Cortex Eucommiae, 13 parts of Morinda officinalis, 14 parts of Radix Astragali and toast 4 parts of Radix Glycyrrhizae;
The lump in the abdomen analgesia side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:12 parts of Radix Codonopsis, 22 parts of Radix Astragali, 10 parts of the root of three-nerved spicebush, Radix Salviae Miltiorrhizae 17 Part, 12 parts of turtle shell, 12 parts of Cortex Eucommiae, 15 parts of Morinda officinalis, 22 parts of honeysuckle, 13 parts of Fructus Forsythiae, 45 parts of field pennycress, fry 25 parts of coix seed, 7 parts of 17 parts of the Chinese bulbul and honey-fried licorice root;
The lump in the abdomen bowel lavage side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:13 parts of kelp, 13 parts of seaweed, 13 parts of edible tulip, radix paeoniae rubra 12 parts of 13 parts, 17 parts of Sargent gloryvine, 27 parts of bittersweet, 27 parts of field pennycress, 12 parts of the coptis and the sophora bud.
Embodiment 3
A kind of serial medicine for treating chronic pelvic pain, including relieving pain of dysmenorrhea side, disappear lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears;
Wherein, relieving pain of dysmenorrhea is made of the bulk pharmaceutical chemicals of following parts by weight:12 parts of peach kernel, 10 parts of ground bettle, 30 parts of motherwort, 12 parts of corydalis tuber, 12 parts of the root bark of tree peony, 12 parts of radix ampelopsis, 30 parts of oldenlandia diffusa, 15 parts of Cortex Eucommiae, 15 parts of Morinda officinalis, 18 parts of Radix Astragali and toast 6 parts of Radix Glycyrrhizae;
The lump in the abdomen analgesia side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:15 parts of Radix Codonopsis, 25 parts of Radix Astragali, 12 parts of the root of three-nerved spicebush, Radix Salviae Miltiorrhizae 20 Part, 15 parts of turtle shell, 15 parts of Cortex Eucommiae, 18 parts of Morinda officinalis, 30 parts of honeysuckle, 15 parts of Fructus Forsythiae, 50 parts of field pennycress, fry 30 parts of coix seed, 9 parts of 20 parts of the Chinese bulbul and honey-fried licorice root;
The lump in the abdomen bowel lavage side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:15 parts of kelp, 15 parts of seaweed, 15 parts of edible tulip, radix paeoniae rubra 15 parts of 15 parts, 20 parts of Sargent gloryvine, 30 parts of bittersweet, 30 parts of field pennycress, 15 parts of the coptis and the sophora bud.
The serial medicine of this treatment chronic pelvic pain is prepared by following preparation method.
It is this treatment chronic pelvic pain serial medicine preparation method include the preparation of relieving pain of dysmenorrhea side, the lump in the abdomen that disappears analgesia side It prepares and the preparation for the lump in the abdomen bowel lavage side that disappears;
Wherein, the preparation process of relieving pain of dysmenorrhea side is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite, cold water is used in combination to impregnate 25min~35min, the dosage of cold water For the high drug plane 2cm~3cm of the water surface in marmite;Secondly, it after boiling by intense fire, uses instead and is cooked by slow fire 25min~35min, filter, It obtains first time filter residue and first time concoction is for use;Again, water is added into first time filter residue, is boiled by intense fire, is changed and be cooked by slow fire 15min~25min, filtering, obtains filter residue and second of concoction, wherein second of concoction is for use;Finally, and by second of concoction It is mixed with first time concoction, obtains relieving pain of dysmenorrhea side;
The preparation process of the lump in the abdomen that disappears analgesia side is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite, cold water is used in combination to impregnate 30min~1h, the dosage of cold water is The high drug plane 2cm~3cm of the water surface in marmite;Secondly, it after boiling by intense fire, uses instead and is cooked by slow fire 30min~40min, filter, obtain It is for use to first time filter residue and first time concoction;Again, water is added into first time filter residue, is boiled by intense fire, is changed and be cooked by slow fire 20min ~30min, filtering, obtains filter residue and second of concoction, wherein second of concoction is for use;Finally, and by second of concoction and Concoction mixing, obtains the lump in the abdomen analgesia side that disappears;
The preparation process of the lump in the abdomen that disappears bowel lavage side is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite;Secondly, 30min~1h, the dosage of cold water are impregnated with cold water For the high drug plane 2cm~3cm of the water surface in marmite;Again, it after boiling by intense fire, uses instead and is cooked by slow fire 40min~50min, filter, Obtain the lump in the abdomen bowel lavage side that disappears.
The invention has the advantages that physical feature of the present invention according to women after intermenstrual period and menstruation, while will be interior Clothes and external application be combined, have efficacy result it is notable, uneasy to recur, non-evident effect, patient is easy to receive, therapeutic process without The advantages that painful, and can be that numerous chronic pelvic pain patients release pain, it improves the quality of living.
In order to better illustrate the therapeutic effect of the present invention, clinical data of the patient using drug of the present invention is now provided:
One, general information
Chronic pelvic pain Patients with 300 Cases is randomly selected, the age, average age was 35.2 years old at 22~45 years old.
(1), diagnostic criteria
It is formulated with reference to disease prevention and control center of the U.S. in 2015《Sexually transmitted disease treatment guidelines》Middle pelvic inflammatory disease Sick diagnostic criteria is drafted.
(1) medical history:The past pelvic inflammatory disease medical history.
(2) symptom:1. using pelvic pain as main clinic symptoms, intermittently or continually property pain, the time more than 6 months, pain Position includes:Pelvic cavity, preceding stomach wall, lumbosacral region and buttocks, symptom may aggravate in menstrual period;2. intercourse pain:There can be intercourse pain;3. low It is hot, tired:Entire patient's symptom usually unobvious, some patients have a symptoms such as low-heat, tired, course of disease elder may occur in which insomnia, Apathetic equal neurasthenia symptoms.
(3) gynaecology examines Check:1. uterus is in retroversioflexion position more, limitation of activity can be with or without uterus tenderness;2. if defeated ovum When pipe inflammation, in palace, the accessible fallopian tubal in streak thickening of body unilateral or bilateral, there is tenderness;3. if hydrosalpinx or defeated When oviduct ovarian cyst, then cystic mass can be touched in pelvic cavity unilateral or bilateral, limitation of activity there can be tenderness;4. if pelvic cavity Inflammation of connective tissue, then in palace body unilateral or bilateral can roll over and it is flaky thicken, have tenderness or accessible uterosacral ligament thickening, It is hardened, touches a tender spot.
(4) auxiliary examination:1. B ultrasound:It is normal or can visit and one or both sides adnexal tumor, pelvic hydrops or hydrosalpinx Deng;2. celioscopy:It can be seen that inflammatory mass is formed in uterus, fallopian tubal, pelvic adhesion lesion or pelvic cavity or fallopian tubal accumulates Water, the locking of umbrella end etc..
Note:The above symptom, sign and auxiliary examination at least need to be provided simultaneously with following two:(1) based on pelvic pain Clinical symptoms are wanted, intermittently or continually property pain, the time, painful area included more than 6 months:Pelvic cavity, preceding stomach wall, lumbosacral region and stern Portion;(2) uterine activity is limited or uterus is fixed with tenderness;Attachment area (strand thickening thickens or in the form of sheets in mass shape) pressure Bitterly.
(2), therapy
Patient starts to take relieving pain of dysmenorrhea side on the 1st day in menstrual period, even served 5 days;Start to take within the 6th day the lump in the abdomen analgesia that disappears in menstruation Side, even served 20 days;Disappear lump in the abdomen bowel lavage side starting external application after net 3 days, when bowel lavage, 37 DEG C or so of fluid temperature, patient, which takes, to lie on one's side Position, disposable enemas tube are inserted into anus 25cm~30cm, blow slowly through disposable enemas tube after syringe taking liquid and inject rectum, protect It is left to few 2h, is used in conjunction 15 days.
(3), criterion is treated
Recovery from illness:Clinical symptoms, sign all disappear, and gynecologial examination is normal, and follow-up 1 year or more is not recurred;
It is effective:Clinical symptoms disappear substantially, the significant improvement of gynecologial examination;
Effectively:Clinical symptoms, sign and inspection have notable mitigation;
In vain:Symptom, sign and gynecologial examination without improvement or aggravate after treatment.
(4), treatment results
In 300 chronic pelvic pain patients, after treatment, fully recovers 196, account for 65.3%;Effective 75, account for 25%; Effective 29,9.7%;Invalid 0.Total effective rate is up to 100%.
Two, model case:
Case 1:
Guo so-and-so, 27 years old, 2017.07.21 first visits.
Patient had found that Right Lower Abdomen interruption takes out tug sample because " discontinuity Right Lower Abdomen pain 9 years aggravated more than January " is medical before 9 years Bitterly, do not pay attention to not treating.Pelvic adhesion is found when two years ago Cesarean esction, and carry out adherence Separation.Nearly underbelly pain right more than January is earlier above It aggravates, more with leukorrhea amount, yellow when blueness when color, vulva is without itch;Appetite is poor, dormancy can, stool is partially dilute, and tongue nature is light dark, heel teeth trace, in Rear portion yellow,greasy and thin fur, soft and thready pulse number.Pregnant 1 cuts open 1, usual menstruation 8 days/23 days, LMP:7.4.Gynaecological examination:Posterior fornix touches a tubercle, There is tenderness, attachment tenderness ++.Diagnosis:Married woman's abdominal pain (chronic pelvic pain).
First visit uses prescription:Inducing meastruation to relieve menalgia side and the lump in the abdomen analgesia side that disappears, wherein inducing meastruation to relieve menalgia side 6 pays, and are opened on the 1st day in menstrual period Beginning takes, daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day;15 pairs of the lump in the abdomen that disappears analgesia side, and opened within the 7th day in menstruation Beginning takes the lump in the abdomen analgesia side that disappears, daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day.
Patient is in 2017.08.08 further consultations.
Patient LMP:7.28, amount is more, color can, menstruation 7 days is net, and the medication rear right pain of lower abdomen mitigates earlier above, and food of receiving improves, and defecates Partially dilute and day is primary, and yellow complexion, tongue nature is light, red tip of tongue, heel teeth trace, and without tongue, middle and back moss thin yellow is slightly greasy for tongue front, and soft and thready pulse is slided Number.
Further consultation uses prescription:The lump in the abdomen that disappears analgesia side, inducing meastruation to relieve menalgia side and the lump in the abdomen bowel lavage side that disappears.15 pairs of the lump in the abdomen that wherein disappears analgesia side, and Start to take within the 7th day the lump in the abdomen analgesia side that disappears in menstruation, it is daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day.It is inducing meastruation to relieve menalgia 5 pairs of side, and start to take within the 1st day in menstrual period, it is daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day.The lump in the abdomen that disappears bowel lavage side 15 pairs, decocting, retention enema disappears lump in the abdomen bowel lavage side in starting external application after net 3 days, daily one pair, when bowel lavage, 37 DEG C of fluid temperature Left and right, patient take lateral position, and disposable enemas tube is inserted into anus 25cm~30cm, through disposable enemas tube after syringe taking liquid Slowly rectum is injected, retains at least 2h, is used in conjunction 15 days.
2017.08.29 three examine.
LMP:8.22, existing D8 days, measure color can, through will be net.Underbelly pain, bellyache in menstrual period are substantially reduced after medication, right side underbelly Occasionally have hypodynia, appetite is poor, dormancy can, stool it is dilute, once a day, dark tongue quality, heel teeth trace, middle and back yellow and greasy fur, arteries and veins moistens weak.
Three examine using prescription:The lump in the abdomen that disappears analgesia side, inducing meastruation to relieve menalgia side and the lump in the abdomen bowel lavage side that disappears.24 pairs of the lump in the abdomen that wherein disappears analgesia side, and Start to take within the 7th day the lump in the abdomen analgesia side that disappears in menstruation, it is daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day.It is inducing meastruation to relieve menalgia 5 pairs of side, and start to take within the 1st day in menstrual period, it is daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day.The lump in the abdomen that disappears bowel lavage side 20 pairs, decocting, retention enema disappears lump in the abdomen bowel lavage side in starting external application after net 3 days, daily one pair, when bowel lavage, 37 DEG C of fluid temperature Left and right, patient take lateral position, and disposable enemas tube is inserted into anus 25cm~30cm, through disposable enemas tube after syringe taking liquid Slowly rectum is injected, retains at least 2h, is used in conjunction 20 days.
Follow-up after 1 month:Abdominal pain disappears substantially.
Case 2
Zhu, 32 years old, 2009.1.5 first visits.
Patient is hidden through often there is underbelly after spontaneous abortion uterine curettage before 1 year because " nearly 1 year of miscarriage low back abdomen pain " is medical Bitterly, waist sacrum pendant pain is uncomfortable, and menstrual period aggravate, and it is ineffective to be once interrupted integrative therapy.Tongue nature is dim red, while having indentation, petechia, tongue fur Yellow greasy, deep thready pulse.Usual menstruation 5 days/23-27 days, LMP:2008.12.22.Diagnosis:Married woman's abdominal pain (chronic pelvic pain)
First visit uses prescription:Disappear lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears, wherein 10 pairs of the lump in the abdomen analgesia side that disappears, and in menstruation the 7th day Start to take the lump in the abdomen analgesia side that disappears, it is daily one pair, oral in warmly taking after morning and evening dinner daily, twice a day.The lump in the abdomen that disappears bowel lavage side 10 is paid, water It decocts, retention enema, disappears lump in the abdomen bowel lavage side in starting external application after net 3 days, daily one pair, when bowel lavage, 37 DEG C or so of fluid temperature is suffered from Person takes lateral position, disposable enemas tube to be inserted into anus 25cm~30cm, noted slowly through disposable enemas tube after syringe taking liquid Enter rectum, retains at least 2h, be used in conjunction 10 days.
2009.1.15 further consultation.
Medication low back abdomen pain symptom mitigates earlier above.In view of menstruation will be damp, give and making the best use of the situation, invigorate blood circulation, to promote to pass through Blood passes unimpeded.Suspend disappear lump in the abdomen analgesia and the lump in the abdomen bowel lavage side that disappears.It sentences inducing meastruation to relieve menalgia side 6 to pay, day one pays, and takes orally, twice a day.
2009.1.23 three examine.
LMP:2009.1.15 late, amount is medium, and chromaticness is normal, and menstrual period, only slight waist was aching and tired, remaining no discomfort, and 7 days through net. It later using inducing meastruation to relieve menalgia side, the lump in the abdomen that disappears analgesia side, the medication stage by stage of the lump in the abdomen that disappears bowel lavage side, adds and subtracts, treats 3 months altogether, waist according to the state of an illness Abdomen pain symptom disappears substantially.Mid-April is discontinued.7.20 have been pregnant nearly 12 weeks in our hospital's inspection.
In conclusion the serial prescription therapeutic effect of the present invention is notable and uneasy to recur.
Disclosed above is only presently preferred embodiments of the present invention, and still, the embodiment of the present invention is not limited to this, Ren Heben What the technical staff in field can think variation should all fall into protection scope of the present invention.

Claims (2)

1. a kind of serial medicine for treating chronic pelvic pain, which is characterized in that including relieving pain of dysmenorrhea side, disappear lump in the abdomen analgesia side and the lump in the abdomen that disappears filling Intestines side;
Wherein, the relieving pain of dysmenorrhea side is made of the bulk pharmaceutical chemicals of following parts by weight:9~12 parts of peach kernel, 6~10 parts of ground bettle, benefit 25~30 parts of Brittle Falsepimpernel Herb, 9~12 parts of corydalis tuber, 9~12 parts of the root bark of tree peony, 9~12 parts of radix ampelopsis, 25~30 parts of oldenlandia diffusa, Cortex Eucommiae 12 3~6 parts of~15 parts, 12~15 parts of Morinda officinalis, 12~18 parts of Radix Astragali and honey-fried licorice root;
The lump in the abdomen analgesia side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:10~15 parts of Radix Codonopsis, 18~25 parts of Radix Astragali, the root of three-nerved spicebush 9~ 12 parts, 15~20 parts of Radix Salviae Miltiorrhizae, 10~15 parts of turtle shell, 12~15 parts of Cortex Eucommiae, 12~18 parts of Morinda officinalis, 25~30 parts of honeysuckle, even It sticks up 10~15 parts, 40~50 parts of field pennycress, fry 6~9 parts of 20~30 parts of coix seed, 15~20 parts of the Chinese bulbul and honey-fried licorice root;
The lump in the abdomen bowel lavage side that disappears is made of the bulk pharmaceutical chemicals of following parts by weight:12~15 parts of kelp, 12~15 parts of seaweed, edible tulip 12 ~15 parts, 12~15 parts of radix paeoniae rubra, 15~20 parts of Sargent gloryvine, 25~30 parts of bittersweet, 25~30 parts of field pennycress, 10~15 parts of the coptis and 10~15 parts of the sophora bud.
2. a kind of preparation method of serial medicine that treating chronic pelvic pain, which is characterized in that preparation including relieving pain of dysmenorrhea side disappears The preparation of the preparation of lump in the abdomen analgesia side and the lump in the abdomen bowel lavage side that disappears;
Wherein, the preparation process of the relieving pain of dysmenorrhea side is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite, is used in combination cold water to impregnate 25min~35min, the dosage of cold water is sand The high drug plane 2cm~3cm of the water surface in pot;Secondly, it after boiling by intense fire, uses instead and is cooked by slow fire 25min~35min, filter, obtain First time filter residue and first time concoction are for use;Again, into first time filter residue plus water, boil by intense fire, change be cooked by slow fire 15min~ 25min, filtering, obtains filter residue and second of concoction, wherein second of concoction is for use;Finally, and by second of concoction and first Secondary concoction mixing, obtains relieving pain of dysmenorrhea side;
The preparation process of the lump in the abdomen analgesia side that disappears is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite, is used in combination cold water to impregnate 30min~1h, the dosage of cold water is marmite The middle high drug plane 2cm~3cm of the water surface;Secondly, it after boiling by intense fire, uses instead and is cooked by slow fire 30min~40min, filter, obtain the Filter residue and first time concoction are for use;Again, into first time filter residue plus water, boil by intense fire, change be cooked by slow fire 20min~ 30min, filtering, obtains filter residue and second of concoction, wherein second of concoction is for use;Finally, and by second of concoction and first Secondary concoction mixing, obtains the lump in the abdomen analgesia side that disappears;
The preparation process of the lump in the abdomen bowel lavage side that disappears is as follows:
First, bulk pharmaceutical chemicals are weighed according to proportioning to be placed in marmite;Secondly, 30min~1h is impregnated with cold water, the dosage of cold water is sand The high drug plane 2cm~3cm of the water surface in pot;Again, it after boiling by intense fire, uses instead and is cooked by slow fire 40min~50min, filter, obtain The lump in the abdomen that disappears bowel lavage side.
CN201810555830.9A 2018-06-01 2018-06-01 A kind of serial medicine and preparation method thereof for treating chronic pelvic pain Pending CN108434365A (en)

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Publication number Priority date Publication date Assignee Title
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