CN108434042A - A kind of novel daily use chemicals preservative and preparation method thereof - Google Patents
A kind of novel daily use chemicals preservative and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
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Abstract
The invention discloses a kind of novel daily use chemicals preservatives, contain propylene glycol, Phenoxyethanol, sodium benzoate, western pyrrole chloramines and water simultaneously；Also contain folium eucalypti extract, honeysuckle flower extract and pollen pini simultaneously.With broad-spectrum antibacterial, all there is stronger inhibition killing effect for staphylococcus aureus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa and Detection of Porphyromonas, Streptococcus mutans etc., while there is good inhibition to brothers' Aphthovirus and herpes simplex virus.
Description
Technical field
The invention belongs to preservative technology fields, and in particular to a kind of to can be used in the daily chemical products such as cosmetics, wet tissue
Preservative and preparation method thereof.
Background technology
The daily chemical products such as cosmetics, wet tissue are easy, by microbial contamination, to generate during production, storage and use
It foams, spoiled iso-metamorphism phenomenon, may also have largely the substance for stimulating human skin in rotten product, especially for youngster
It is virgin.
Since children are relatively active more active, curiosity is filled with to the external world, often the outgoing children to play are on amusement park and other places
The bacterium that can be infected during climbing with a large amount of extraneous or other children is touched on the amusement toy of side, is in addition eaten with hand
Child can also infect a large amount of oral cavity pathogen or virus during either eating hand and kissing.If infrequently washed
Hand, bacterium and virus are easy to mutually infect with children, lead to a large amount of diseases.And it is frequent when outgoing be inconvenient to wash one's hands, institute
Just become daily necessities indispensable when children outside with children's wet tissue.
The skin of children is relatively thin, and skin is delicate, it is easy to generate phenomena such as eczema is chapped from the cold, need to produce using children's skin care
Product, to prevent from generating eczema because of dry skin and phenomenon of being chapped from the cold, but for having generated eczema, being chapped from the cold even suppuration etc. now
The skin of elephant, either easily the child skin of allergic constitution is easy to increase its redness or routed because of the stimulation of cosmetics or wet tissue
Rotten phenomenon.And the preservative in existing children's daily chemical products does not have broad-spectrum antibacterial, and for the inhibiting effect of virus
Also poor.
Disclosed in Chinese patent CN201510287960.5 a kind of anticorrosive composite its contain Flos Caryophylli extract, ginkgo carries
Take arbitrary two kinds or more in the smooth caprylate of object, coptis extract, sorb of combination.The composition is equal to various bacteria, fungi
With inhibitory or killing effect.When being particularly suitable in cosmetics, skin allergy or pigment deposition, colour of skin flavescence etc. will not be caused to ask
Topic.The invention also discloses the cosmetics containing the anticorrosive composite.But composition does not have broad-spectrum antibacterial in the invention
Property, and it is poor for the inhibiting effect of virus.
A kind of oil control and acne removal wet tissue with plant Compositional antiseptic agent is disclosed in Chinese patent CN201510660331.2,
It is made of with each component of parts by weight following：5~10 parts of Oil suction powder, 60~70 parts of fresh aloe juice, royal jelly extract 1~5
Part, 1~5 part of Salvia root P.E, 1~5 part of flower of Fructus Mali pumilae extract, 1~5 part of sugar Thallus Laminariae (Thallus Eckloniae) extract, 5~10 parts of allantoin, mung bean
1~5 part of powder, 1~5 part of Lavender, 0.1~0.3 part of plant Compositional antiseptic agent, 20~25 parts of deionized water.The patent has
There is the oil control and acne removal wet tissue of plant Compositional antiseptic agent that can reduce fat secretion, absorb skin oil and fat, and with good anti-acne, scar of dispelling
Trace and promotion skin repair effect, it is with obvious effects, it is easy to use, it is suitable for neutral to oily skin；Meanwhile the plant added
Compositional antiseptic agent can effectively inhibit the growth of the microorganisms such as bacterium in skin care item, fungi, extend skin care item service life.But it should
Multiple components in patent there may be sensitization, do not have a broad-spectrum antibacterial for children and allergic skin, and for
The inhibiting effect of virus is poor.
Invention content
For the above deficiency, the present invention is directed at least solve one of prior art problem, the present invention provides a kind of novel
Daily use chemicals preservative, with broad-spectrum antibacterial and to herpes simplex virus with good inhibition.
Technical scheme is as follows：A kind of novel daily use chemicals preservative contains propylene glycol, Phenoxyethanol, benzene first simultaneously
Sour sodium, western pyrrole chloramines and water.
The present invention has broad-spectrum antibacterial using three kinds of Phenoxyethanol, sodium benzoate, western pyrrole chloramines antiseptic and inhibiting bacteria function agent combinations
Property, for staphylococcus aureus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa and Detection of Porphyromonas and Streptococcus mutans
Deng all have stronger inhibition killing effect, while herpes simplex virus have good inhibition.Wherein Phenoxyethanol, west
Two kinds of bacteriostatic agents of pyrrole chloramines have synergistic effect between each other, enhance mutual antibacterial activity, three kinds of antiseptic and inhibiting bacteria function agent are dissolved in
In water and propylene glycol, various pH environment can be widely used in, there can be good fungistatic effect in different skin.And
It can reach good fungistatic effect using less amount of preservative, it is small to the stimulation of skin.
Preferably, the Phenoxyethanol and western pyrrole the chloramines shared mass percent in preservative are respectively 30% and 5%.
The Phenoxyethanol of this programme preferred mass percentage and western pyrrole chloramines can preferably play synergistic effect in preservative, reduce
Its minimal inhibitory concentration, the minimal inhibitory concentration of Phenoxyethanol and western pyrrole chloramines can be down to 0.03% in preservative in this programme
With 0.005%.
Preferably, also contain folium eucalypti extract, honeysuckle flower extract and pollen pini in the above preservative simultaneously.In preservative
Middle folium eucalypti extract, honeysuckle flower extract and pollen pini these three substances of being added can improve the sensitive skin quality of children, especially
It has some improvement for being easy the symptoms such as eczema generation is suppurated, and bleb is festered；And it can inhibit and kill tool core shuttle
Bacillus, Prevotella intermedia and hand-foot-and-mouth disease virus EV71.
Preferably, the folium eucalypti extract is the acetic acid ethyl ester extract of eucalyptus robusta, the big fruit eucalyptus that folium eucalypti extract provides
Content of the aldehyde in preservative is 0.5~2mg/mL；The honeysuckle flower extract is ethanol extract, and honeysuckle flower extract provides
Content of the chlorogenic acid in preservative be 5~20mg/mL；Content of the pollen pini in preservative is 1~4%.We
The preferred folium eucalypti extract of case, honeysuckle flower extract and the pollen pini dosage collocation raw materials such as Phenoxyethanol and western pyrrole chloramines can be protected
Card is using a small amount of preservative of the invention, wherein each ingredient can play good fungistatic effect.
Preferably, the content ratio of the big fruit eucalyptus aldehyde and chlorogenic acid in preservative is 1:10.Using the big fruit eucalyptus of this programme
The concentration ratio of aldehyde and chlorogenic acid can preferably inhibit and kill virus EV71.
Preferably, the propylene glycol and the sodium benzoate shared mass percent in preservative are respectively 20.0% He
10.0%.The sodium benzoate for adding special ratios can also have good inhibiting effect to saccharomycete, mould.Special ratios third
The cooperation of two alcohol and waters can preferably dissolve various bacteriostatic agents.
The present invention also provides a kind of above-mentioned preparation methods of novel daily use chemicals preservative, are extracted when not adding folium eucalypti in preservative
When object, honeysuckle flower extract and pollen pini, preparation method is as follows：
Mixed liquor A:Propylene glycol is uniformly mixed with Phenoxyethanol, then western pyrrole chloramines is dissolved in wherein while stirring, is stirred
Mix mixing；
Mixed liquid B：It is under stiring that sodium benzoate is soluble in water, until sodium benzoate is completely dissolved as clear solution；
Mixed liquor：Mixed liquor A and mixed liquid B are uniformly mixed as clear solution under stiring.
When adding folium eucalypti extract, honeysuckle flower extract and pollen pini in preservative, preparation method is as follows：
Mixed liquor A：Propylene glycol is uniformly mixed with Phenoxyethanol, then western pyrrole chloramines is dissolved in wherein while stirring, is stirred
Mix mixing；
Mixed liquid B：It is under stiring that sodium benzoate is soluble in water, until sodium benzoate is completely dissolved as clear solution；
Mixed liquor C：Folium eucalypti extract, honeysuckle flower extract and pollen pini are added in mixed liquid B and stirred evenly；
Mixed liquor：Mixed liquor A and mixed liquor C are uniformly mixed as clear solution under stiring.
The preparation method of the present invention is simple, and raw material is easy to get, and the preservative performance of preparation is stablized, and has good broad-spectrum antibacterial
Property.
Compared with prior art, the beneficial effects of the present invention are：(1) there is broad-spectrum antibacterial；(2) it can inhibit and kill
The children's Causative virus for going out several frequently seen；(3) it is used in wet tissue and cosmetics, usage amount is few, does not stimulate skin；(4) for wet
The symptoms such as rash is suppurated, and bleb is festered have some improvement；(5) preparation method is simple, and raw material is easy to get；Properties of product are stablized.
Specific implementation mode
A kind of novel daily use chemicals preservative of the present invention, contain simultaneously propylene glycol, Phenoxyethanol, sodium benzoate, western pyrrole chloramines and
Water.
Preferably, it can also include folium eucalypti extract, honeysuckle flower extract and pollen pini.
More electedly, the folium eucalypti extract is the acetic acid ethyl ester extract of eucalyptus robusta, the big fruit that folium eucalypti extract provides
Content of the eucalyptus aldehyde in preservative is 0.5~2mg/mL；The honeysuckle flower extract is ethanol extract, and honeysuckle flower extract carries
Content of the chlorogenic acid of confession in preservative is 5~20mg/mL；Content of the pollen pini in preservative is 1~4%.
Folium eucalypti extract described in the embodiment of the present invention is folium eucalypti extracting solution：Preparation method is as follows：
Folium eucalypti extracting solution：Using Chinese herbal medicine eucalyptus robusta as raw material, extracting solution that ethyl acetate is obtained by extraction.Eucalyptus robusta is dried
It pulverizes and sieves, using ethyl acetate as Extraction solvent, microwave abstracting 2h, centrifugation, filtering collect filtrate, through rotary evaporation, concentration removes
Ethyl alcohol is removed, folium eucalypti extracting solution is obtained.
Honeysuckle flower extract described in the embodiment of the present invention is honeysuckle flowers extracting solution：Preparation method is as follows：
Honeysuckle flowers extracting solution：Using Chinese herbal medicine honeysuckle flowers as raw material, extracting solution that ethyl alcohol is obtained by extraction.By honeysuckle flowers xeraphium
Broken sieving, using ethyl alcohol as Extraction solvent, filtrate is collected in microwave abstracting 2h, centrifugation, filtering, and through rotary evaporation, concentration removes second
Alcohol obtains honeysuckle flowers extracting solution.
When pollen pini described in the embodiment of the present invention is that horse hair preserved egg is just opened, flower spike is picked, is dried, pollen is collected, removes
Decontamination is prepared.
Clear, complete description is carried out to each technical solution of the present invention with reference to embodiments, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiment of the present invention, this field is common
Technical staff's obtained all other embodiment without making creative work belongs to the present invention and is protected
Range.Those skilled in the art are according to the equivalent transformation of method, process route, function made by following implementation or replace
Generation, all belong to the scope of protection of the present invention within.
Embodiment 1
A kind of novel daily use chemicals preservative of the present embodiment, wherein including：Propylene glycol 20.0%, Phenoxyethanol 30.0%, benzene
Sodium formate 10.0%, western pyrrole chloramines 5.0%, surplus is water.
A kind of novel daily use chemicals preservative preparation method of the present embodiment is as follows：
Mixed liquor A:Propylene glycol is uniformly mixed with Phenoxyethanol, then western pyrrole chloramines is dissolved in wherein while stirring, is stirred
Mix mixing；
Mixed liquid B：It is under stiring that sodium benzoate is soluble in water, until sodium benzoate is completely dissolved as clear solution；
Mixed liquor C：Folium eucalypti extract, honeysuckle flower extract and pollen pini are added in mixed liquid B and stirred evenly；
Mixed liquor:Mixed liquor A and mixed liquor C are uniformly mixed as clear solution under stiring.
Embodiment 2
A kind of novel daily use chemicals preservative of the present embodiment, wherein including：Propylene glycol 20.0%, Phenoxyethanol 25.0%, benzene
Sodium formate 10.0%, western pyrrole chloramines 10.0%, surplus is water.
Preparation method is the same as embodiment 1.
Embodiment 3
A kind of novel daily use chemicals preservative of the present embodiment, wherein including：Propylene glycol 20.0%, Phenoxyethanol 38.0%, benzene
Sodium formate 10.0%, western pyrrole chloramines 2.0%, surplus is water.
Preparation method is the same as embodiment 1.
Embodiment 4
A kind of novel daily use chemicals preservative of the present embodiment, wherein including：Propylene glycol 20.0%, Phenoxyethanol 30.0%, benzene
Sodium formate 10.0%, western pyrrole chloramines 5.0%；Also include folium eucalypti extract, honeysuckle flower extract and pollen pini；Wherein folium eucalypti extracts
Content of the big fruit eucalyptus aldehyde that object provides in preservative is 1.0mg/mL；The chlorogenic acid that the honeysuckle flower extract provides is in anti-corrosion
Content in agent is 10.0mg/mL；Content of the pollen pini in preservative is 2%；Surplus is water.
A kind of preparation method of novel daily use chemicals preservative of the present embodiment is as follows：
Mixed liquor A:Propylene glycol is uniformly mixed with Phenoxyethanol, then western pyrrole chloramines is dissolved in wherein while stirring, is stirred
Mix mixing；
Mixed liquid B：It is under stiring that sodium benzoate is soluble in water, until sodium benzoate is completely dissolved as clear solution；
Mixed liquor C：Folium eucalypti extract, honeysuckle flower extract and pollen pini are added in mixed liquid B and stirred evenly；
Mixed liquor:Mixed liquor A and mixed liquor C are uniformly mixed as clear solution under stiring.
Embodiment 5
Compared with Example 4, content of the big fruit eucalyptus aldehyde of the present embodiment folium eucalypti extract offer in preservative is
5.0mg/mL；Content of the chlorogenic acid that the honeysuckle flower extract provides in preservative is 6.0mg/mL；The pollen pini exists
Content in preservative is 6%；It is other same as Example 4.
Embodiment 6
Compared with Example 4, pollen pini is not contained in the present embodiment, it is other same as Example 4.
Comparative example 1
Compared with Example 1, a kind of novel daily use chemicals preservative of this comparative example, wherein including：Propylene glycol 20.0%, benzene oxygen second
Alcohol 30.0%, sodium benzoate 10.0%, surplus are water.It is other same as Example 1.
Comparative example 2
Compared with Example 1, a kind of novel daily use chemicals preservative of this comparative example, wherein including：Propylene glycol 20.0%, benzoic acid
Sodium 10.0%, western pyrrole chloramines 5.0%, surplus is water.It is other same as Example 1.
Comparative example 3
Compared with Example 4, this comparative example does not add folium eucalypti extract, honeysuckle flower extract and pollen pini, and adds fragrant
Extracting solution, ginkgo extract, rhizoma extracting liquid and the smooth caprylate composition of sorb, cloves extracting solution, ginkgo extract, coptis extraction
The content of fragrant phenol, GINKGO BILOBA EXTRACT and jamaicin is respectively 0.8mg/mL, 2mg/mL, 0.6mg/mL in liquid；The smooth caprylate matter of sorb
It is 5% to measure score.
Comparative example 4
A kind of daily use chemicals preservative of this comparative example is by cloves extracting solution, ginkgo extract, rhizoma extracting liquid and the smooth octanoic acid of sorb
Ester forms, and the content of fragrant phenol, GINKGO BILOBA EXTRACT and jamaicin is respectively in cloves extracting solution, ginkgo extract, rhizoma extracting liquid
0.8mg/mL、2mg/mL、0.6mg/mL；The smooth caprylate mass fraction of sorb is 5%.
The preservative sample of embodiment 1-6 and comparative example 1-4 is diluted to using distilled water to 0.1% content respectively, it is right
The preservative of ratio 4 is diluted with water to 1% content, is then respectively acting on different bacteriums and virus, tests it and inhibits effect
Fruit, as shown in table 1 below.
Table 1：Bacterium and viral suppression
The preservative of the embodiment of the present invention is in 0.1% concentration as can be seen from Table 1, to staphylococcus aureus, large intestine
Bacillus, Candida albicans, Pseudomonas aeruginosa and Detection of Porphyromonas and Streptococcus mutans etc. all have preferable fungistatic effect and right
Also there is preferable inhibition in herpes simplex virus.Add a certain amount of folium eucalypti extract, honeysuckle flower extract and pollen pini
Afterwards, preservative also has preferable inhibition for Fusobacterium nucleatum, Prevotella intermedia and virus EV71.
In addition the present invention is also tested for embodiment 1 to implementing 3 preservative to the minimum of Pseudomonas aeruginosa and Streptococcus mutans
Mlc, respectively 0.01% and 0.04% and 0.06%.Illustrate that according to the formula rate of embodiment 1 preservative can be reduced
Minimum inhibitory concentration.
In addition water is added to prepare 0.1% concentration the preservative of embodiment 1, embodiment 4, comparative example 4 plus water prepare 1%
Concentration, the position for rubbing into 5 children's eczematization purulence respectively are compared 2 times a day, it is found that embodiment 4 can be in 3 days
The eczema of children is significantly improved, does not occur red and swollen phenomenon, and embodiment 1 also has some improvement effect to childhood eczema after 5 days
Fruit, and the preservative of comparative example 4 then has stimulation to Among Children skin, causes it red and swollen or even festers.Illustrate the present invention
Preservative do not stimulate skin and have the function of improve eczema.
In addition it is 3~9 that pH adjusting agent will be added in embodiment 1 and be adjusted to pH, equal to Escherichia coli, Candida albicans
With good fungistatic effect.Illustrate that the preservative of the present invention all has good fungistatic effect within the scope of wider pH.
The basic principles, main features and advantages of the invention have been shown and described above, while there has been shown and described that
The embodiment of the present invention, for the ordinary skill in the art, it is possible to understand that do not departing from the principle of the present invention and essence
A variety of change, modification, replacement and modification can be carried out to these embodiments, the scope of the present invention is by appended right in the case of god
It is required that and its equivalent restriction.
Claims (8)
1. a kind of novel daily use chemicals preservative, which is characterized in that contain propylene glycol, Phenoxyethanol, sodium benzoate, western pyrrole chloramines simultaneously
And water.
2. a kind of novel daily use chemicals preservative according to claim 1, which is characterized in that the Phenoxyethanol and western pyrrole chloramines
Shared mass percent is respectively 30% and 5% in preservative.
3. a kind of novel daily use chemicals preservative according to claim 1, which is characterized in that also simultaneously contain folium eucalypti extract,
Honeysuckle flower extract and pollen pini.
4. a kind of novel daily use chemicals preservative according to claim 3, which is characterized in that the folium eucalypti extract provides big
Content of the fruit eucalyptus aldehyde in preservative is 0.5~2mg/mL；The chlorogenic acid that the honeysuckle flower extract provides is in preservative
Content is 5~20mg/mL；Content of the pollen pini in preservative is 1~4%.
5. a kind of novel daily use chemicals preservative according to claim 4, which is characterized in that the big fruit eucalyptus aldehyde and chlorogenic acid exist
Content ratio in preservative is 1:10.
6. according to a kind of novel daily use chemicals preservative of claim 1 to 5 any one of them, which is characterized in that the propylene glycol and
Sodium benzoate shared mass percent in preservative is respectively 20.0% and 10.0%.
7. a kind of preparation method of novel daily use chemicals preservative described in claim 1, which is characterized in that include the following steps：
Mixed liquor A：Propylene glycol is uniformly mixed with Phenoxyethanol, is then while stirring dissolved in western pyrrole chloramines wherein, stirring is mixed
It is even；
Mixed liquid B：It is under stiring that sodium benzoate is soluble in water, until sodium benzoate is completely dissolved as clear solution；
Mixed liquor：Mixed liquor A and mixed liquid B are uniformly mixed as clear solution under stiring.
8. a kind of preparation method of novel daily use chemicals preservative described in claim 3, which is characterized in that include the following steps：
Mixed liquor A：Propylene glycol is uniformly mixed with Phenoxyethanol, is then while stirring dissolved in western pyrrole chloramines wherein, stirring is mixed
It is even；
Mixed liquid B：It is under stiring that sodium benzoate is soluble in water, until sodium benzoate is completely dissolved as clear solution；
Mixed liquor C：Folium eucalypti extract, honeysuckle flower extract and pollen pini are added in mixed liquid B and stirred evenly；
Mixed liquor：Mixed liquor A and mixed liquor C are uniformly mixed as clear solution under stiring.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346124A (en) * | 2020-02-10 | 2020-06-30 | 江苏景奥科技发展有限公司 | Formula and preparation method of skin disinfection cleaning solution |
| CN114344350A (en) * | 2021-12-31 | 2022-04-15 | 吉林大学 | Application of artemisia pigweed extract |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346124A (en) * | 2020-02-10 | 2020-06-30 | 江苏景奥科技发展有限公司 | Formula and preparation method of skin disinfection cleaning solution |
| CN114344350A (en) * | 2021-12-31 | 2022-04-15 | 吉林大学 | Application of artemisia pigweed extract |
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