CN108434028A - A kind of Chinese medical extract and its application as cosmetic additive agent - Google Patents
A kind of Chinese medical extract and its application as cosmetic additive agent Download PDFInfo
- Publication number
- CN108434028A CN108434028A CN201810216273.8A CN201810216273A CN108434028A CN 108434028 A CN108434028 A CN 108434028A CN 201810216273 A CN201810216273 A CN 201810216273A CN 108434028 A CN108434028 A CN 108434028A
- Authority
- CN
- China
- Prior art keywords
- hare
- application
- root
- lettuce
- lettuce root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The present invention relates to a kind of Chinese medical extract and its as the application of cosmetic additive agent, and in particular to a kind of hare's-lettuce root extract, preparation method include the following steps：Dry common sowthistle root is taken, after being crushed, water is added, refluxing extraction is after 5 10 hours, cooled to room temperature, filtering, and filtrate is through activated carbon decolorizing, concentration, dry the hare's-lettuce root extract.
Description
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of Chinese medical extract and its answering as cosmetic additive agent
With.
Background technology
Common sowthistle root is the root of feverfew hare's-lettuce, is a kind of Chinese medicine, is distributed in China northeast and southern various regions, has drop
The effect of sugar, lipid-loweringing, clearing deficient heat.Cortex acanthopanacis is the dry root skin of Araliaceae acanthopanax gracilistylus, excavates root in summer, two season of autumn
Portion cleans, strips root skin, dry；There is wind-damp dispelling, tonify the liver and kidney, strengthens muscles and bones, the effect of inducing diuresis for removing edema.Have been reported that wilsonii
Extract can be used for cosmetics, to remove pigment deposition caused by acne or tender white muscle skin.A kind of common sowthistle root of present invention offer carries
Object and common sowthistle root and cortex acanthopanacis compound extract are taken, common sowthistle root and cortex acanthopanacis in terms of radicals scavenging and tyrosinase inhibition
Between show a kind of effect of synergy.
Invention content
The present invention provides a kind of hare's-lettuce root extract, it is characterised in that the preparation method of the hare's-lettuce root extract includes such as
Lower step：
Dry common sowthistle root is taken, after being crushed, water is added, refluxing extraction is after 5-10 hours, cooled to room temperature, mistake
Filter, filtrate is through activated carbon decolorizing, concentration, dry the hare's-lettuce root extract.
The preferred distilled water of water or deionized water, the quality dosage of water are 15-30 times of common sowthistle root quality.
Another embodiment of the present invention provides a kind of preparation method of hare's-lettuce root extract, it is characterised in that including as follows
Step：
Dry common sowthistle root is taken, after being crushed, water is added, refluxing extraction is after 5-10 hours, cooled to room temperature, mistake
Filter, filtrate is through activated carbon decolorizing, concentration, dry the hare's-lettuce root extract.
The preferred distilled water of water or deionized water, the quality dosage of water are 15-30 times of common sowthistle root quality.
Another embodiment of the present invention provides application of the above-mentioned hare's-lettuce root extract as antioxidant.
Another embodiment of the present invention provides application of the above-mentioned hare's-lettuce root extract in terms of removing free radical.It is described from
By the preferred DPPH free radicals of base, ultra-oxygen anion free radical.
Another embodiment of the present invention provides application of the above-mentioned hare's-lettuce root extract in inhibiting tyrosinase.
Another embodiment of the present invention provides application of the above-mentioned hare's-lettuce root extract as cosmetic additive agent.Describedization
The preferred whitening agent of cosmetic, sun-screening agent etc..
Another embodiment of the present invention provides application of the above-mentioned hare's-lettuce root extract in terms of preparing cosmetics.
The present invention provides a kind of compound Chinese medicine extract, it is characterised in that the formula of the herbal mixture described by weight is
1 part of common sowthistle root, 3-5 parts of cortex acanthopanacis.
Another embodiment of the present invention provides above-mentioned compound Chinese medicine extract, it is characterised in that the herbal mixture extraction
The preparation method of object, includes the following steps：
Dry common sowthistle root and cortex acanthopanacis are measured by formula, water, refluxing extraction 5-10 hours is added in mixing after being crushed
Afterwards, cooled to room temperature, filtering, filtrate is through activated carbon decolorizing, concentration, dry the compound Chinese medicine extract.
The preferred distilled water of water or deionized water, the quality dosage of water are 15-30 times of common sowthistle root and cortex acanthopanacis quality sum.
Another embodiment of the present invention provides the preparation method of above-mentioned compound Chinese medicine extract, it is characterised in that including such as
Lower step：
Dry common sowthistle root and cortex acanthopanacis are measured by formula, water, refluxing extraction 5-10 hours is added in mixing after being crushed
Afterwards, cooled to room temperature, filtering, filtrate is through activated carbon decolorizing, concentration, dry the compound Chinese medicine extract.
The preferred distilled water of water or deionized water, the quality dosage of water are 15-30 times of common sowthistle root and cortex acanthopanacis quality sum.
Another embodiment of the present invention provides application of the above-mentioned compound Chinese medicine extract as antioxidant.
Another embodiment of the present invention provides application of the above-mentioned compound Chinese medicine extract in terms of removing free radical.It is described
The preferred DPPH free radicals of free radical, ultra-oxygen anion free radical.
Another embodiment of the present invention provides application of the above-mentioned compound Chinese medicine extract in inhibiting tyrosinase.
Another embodiment of the present invention provides application of the above-mentioned compound Chinese medicine extract as cosmetic additive agent.It is described
The preferred whitening agent of cosmetics, sun-screening agent etc..
Another embodiment of the present invention provides application of the above-mentioned compound Chinese medicine extract in terms of preparing cosmetics.
Common sowthistle root of the present invention, cortex acanthopanacis can be Chinese medicines, can also be the prepared slices of Chinese crude drugs.
Compared with the prior art, the advantages of the present invention are as follows：(1) the present invention provides a kind of common sowthistle root water extract,
Certain activity is shown in terms of radicals scavenging and tyrosinase inhibition, can be used as cosmetic additive agent for whitening or is prevented
Shine agent；(2) the present invention also provides a kind of common sowthistle roots and cortex acanthopanacis compound Chinese medicine extract, and the compound Chinese medicine extract is in free radical
It removes and tyrosinase inhibition aspect shows very strong syneryistic effect.
Specific implementation mode
For the ease of a further understanding of the present invention, examples provided below has done more detailed description to it.But
It is that these embodiments are only not supposed to be a limitation to the present invention or implementation principle for being better understood from invention, reality of the invention
The mode of applying is not limited to the following contents.
Embodiment 1
Dry common sowthistle root (1kg) is taken, after being crushed, distilled water (15kg) is added, refluxing extraction is natural after 5 hours
Be cooled to room temperature, filter, filtrate through activated carbon decolorizing, concentration, (58.6g is hereinafter referred to as produced dry the hare's-lettuce root extract
Product A).
Embodiment 2
Dry common sowthistle root (1kg) is taken, after being crushed, deionized water (30kg) is added, refluxing extraction is after 10 hours, certainly
So be cooled to room temperature, filter, filtrate through activated carbon decolorizing, concentration, dry the hare's-lettuce root extract (63.5g, hereinafter referred to as
Product B).
Embodiment 3
Dry common sowthistle root (1kg) is taken, after being crushed, distilled water (15kg) is added, at room temperature soak extraction 5 hours
Afterwards, it filters, filtrate is through activated carbon decolorizing, concentration, dry hare's-lettuce root extract (17.3g, hereinafter referred to as products C).
Embodiment 4
Dry common sowthistle root (1kg) is taken, after being crushed, distilled water (15kg) is added, soak extraction 5 is small at 60-70 DEG C
Shi Hou, filtering, filtrate is through activated carbon decolorizing, concentration, dry hare's-lettuce root extract (26.2g, hereinafter referred to as product D).
Embodiment 5
Dry cortex acanthopanacis (1kg) is taken, after being crushed, distilled water (15kg) is added, refluxing extraction is natural after 5 hours
It is cooled to room temperature, filters, filtrate is through activated carbon decolorizing, concentration, dry Cortex Acanthopancis extract (48.5g, hereinafter referred to as product
E)。
Embodiment 6
Formula：1 part of common sowthistle root, 3 parts of cortex acanthopanacis
Dry common sowthistle root (200g) and cortex acanthopanacis (600g) are measured by formula, distilled water is added in mixing after being crushed
(12kg), refluxing extraction is after 5 hours, cooled to room temperature, filtering, and filtrate is through activated carbon decolorizing, concentration, dry described again
Square Chinese medical extract (52.3g, hereinafter referred to as product F).
Embodiment 7
Formula：1 part of common sowthistle root, 5 parts of cortex acanthopanacis
Dry common sowthistle root (200g) and cortex acanthopanacis (1000g) are measured by formula, distilled water is added in mixing after being crushed
(36kg), refluxing extraction is after 10 hours, cooled to room temperature, filtering, and filtrate is through activated carbon decolorizing, concentration, dry described
Compound Chinese medicine extract (64.6g, hereinafter referred to as product G).
Embodiment 8
Formula：0.5 part of common sowthistle root, 5 parts of cortex acanthopanacis
Dry common sowthistle root (100g) and cortex acanthopanacis (1000g) are measured by formula, distilled water is added in mixing after being crushed
(16.5kg), refluxing extraction is after 5 hours, cooled to room temperature, filtering, and filtrate is through activated carbon decolorizing, concentration, dry compound
Chinese medical extract (56.4g, hereinafter referred to as product H).
Embodiment 9
It takes suitable product A-H to be dissolved with DMSO, the solution that mass concentration is 0.5mg/mL is configured to, according to Chinese patent
Application number：Method described in CN201710843876.6, the DPPH free radical scavenging abilities of test product A-H, super oxygen the moon from
Sub- Scavenging activity；According to Chinese Patent Application No.：Method described in CN201710196028.0, test product A-H is to junket ammonia
The inhibiting rate of sour enzyme, the results are shown in Table 1.
Table 1
Claims (10)
1. a kind of hare's-lettuce root extract, it is characterised in that the preparation method of the hare's-lettuce root extract includes the following steps：
Dry common sowthistle root is taken, after being crushed, water is added, refluxing extraction is after 5-10 hours, cooled to room temperature, filtering,
Filtrate is through activated carbon decolorizing, concentration, dry the hare's-lettuce root extract.
2. hare's-lettuce root extract described in claim 1, it is characterised in that the preferred distilled water of the water or deionized water, the matter of water
Measure 15-30 times that dosage is common sowthistle root quality.
3. the preparation method of claim 1-2 any one of them hare's-lettuce root extracts.
4. application of the claim 1-2 any one of them hare's-lettuce root extracts as antioxidant.
5. application of the claim 1-2 any one of them hare's-lettuce root extracts in terms of removing free radical.
6. the application described in claim 5, it is characterised in that the preferred DPPH free radicals of the free radical, superoxide anion are free
Base.
7. application of the claim 1-2 any one of them hare's-lettuce root extracts in inhibiting tyrosinase.
8. application of the claim 1-2 any one of them hare's-lettuce root extracts as cosmetic additive agent.
9. application of the claim 1-2 any one of them hare's-lettuce root extracts in terms of preparing cosmetics.
10. claim 8-9 any one of them applications, it is characterised in that the preferred whitening agent of the cosmetics, sun-screening agent etc..
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810216273.8A CN108434028A (en) | 2018-03-15 | 2018-03-15 | A kind of Chinese medical extract and its application as cosmetic additive agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810216273.8A CN108434028A (en) | 2018-03-15 | 2018-03-15 | A kind of Chinese medical extract and its application as cosmetic additive agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108434028A true CN108434028A (en) | 2018-08-24 |
Family
ID=63194795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810216273.8A Pending CN108434028A (en) | 2018-03-15 | 2018-03-15 | A kind of Chinese medical extract and its application as cosmetic additive agent |
Country Status (1)
| Country | Link |
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| CN (1) | CN108434028A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007126367A (en) * | 2005-11-01 | 2007-05-24 | Shiseido Co Ltd | Bleaching ingredient, bleaching method and method for producing bleaching skin care preparation |
-
2018
- 2018-03-15 CN CN201810216273.8A patent/CN108434028A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007126367A (en) * | 2005-11-01 | 2007-05-24 | Shiseido Co Ltd | Bleaching ingredient, bleaching method and method for producing bleaching skin care preparation |
Non-Patent Citations (2)
| Title |
|---|
| THE LOCAL FOOD-NUTRACEUTICALS CONSORTIUM: "Understanding local Mediterranean diets: A multidisciplinary pharmacological and ethnobotanical approach", 《PHARMACOLOGICAL RESEARCH》 * |
| 李凤英等: "21种野菜抗氧化性的分析比较", 《中国食品学报》 * |
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| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20180824 |