CN108420886A - A kind of functional composition and its preparation method and application improving anaemia - Google Patents
A kind of functional composition and its preparation method and application improving anaemia Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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Abstract
The invention discloses a kind of functional composition and its preparation method and application improving anaemia, which includes the ingredient of following parts by weight：10 30 parts of 20 50 parts of Fructus Jujubae extract, 20 50 parts of Semen Phaseoli extract, 10 30 parts of Fructus Mori extract and Fructus lycii P.E；Preparation method includes：After mixing by each components in certain proportion, it is 0.1 7wt% to be dried to moisture, is crushed after sterilizing, and 80 mesh sieve is crossed, in addition pharmaceutically common auxiliary material or complementary ingredient prepare dosage form.The functional composition provided by the present invention for improving anaemia has the function of promoting body to absorption of nutrient ingredients such as iron and protein, it can be very good to improve anaemia, it takes the purpose that can reach control treatment for a long time, and has no apparent toxic effect, edible safety is reliable；Raw materials used abundance is easy to get, and required condition and equipment are simple, simple for process controllable, has highly important actual promotional value.
Description
Technical field
The invention belongs to drugs and field of health care products, and in particular to it is a kind of improve anaemia functional composition and its preparation
Methods and applications.
Background technology
According to statistics, into since 21st century, the anaemia probability of compatriots has been significantly larger than western countries.
It is shown according to the investigation of Chinese Center for Disease Control and Prevention, domestic children anemia rate is 25% or so, women anemia rate
20% or so, pregnant woman anemia rate is up to 35%, and man's anemia rate is then 10% or so, Adolescents in China anaemia
Incidence up to 38%.
Anaemia is very big to the harm of health, and the normal work of each histoorgan of human body is required for " breathing " oxygen, and
Endoerythrocytic hemoglobin is exactly the canoe for transporting oxygen, and when anaemia, the canoe for transporting oxygen is reduced, therefore each organizer
The oxygen that official obtains is reduced therewith, and body is chronically at anaerobic condition, can be generated and be seriously affected to each internal organs.Anemia can make
People feels weak, dizzy, tinnitus, dim eyesight and loss of appetite etc., and anemia may lead to tachycardia, heart failure, even
The serious adverse events such as heart arrest.
For children, old man, pregnant and lying-in women, the influence of anaemia is more far-reaching.Child on long-term anaemia may influence body and
Intellectual development；The long-term anaemia of gerontal patient can cause the risk for suffering from cardiovascular and cerebrovascular disease to increase；Pregnant woman's severe anemia can lead to tire
The serious consequences such as youngster's depauperation, premature labor, stillbirth.
Functional food refer to have trophic function, sensory function and adjust physiological activity function food, including：Enhancing
The food of human body constitution (enhancing immunocompetence, activation lymphatic system etc.)；Prevent disease (hypertension, diabetes, coronary heart disease, just
Secret and tumour etc.) food；It gets well the food of (control cholesterol prevents platelet aggregation, adjusts hematopoiesis function etc.)；It adjusts
Save the food of the food and anti-aging of body rhythms (nerve center, nerve ending, intake and absorption function etc.).Functionality food
The research and development of product still belong to new branch of science and field in China, are the products of multidisciplinary, multi-field continuous mixing together, are related to
Nutrition, pharmacy, physiology, preventive medicine, bioengineering, Food Science.
Therefore, the functional food for developing safely and effectively improvement anaemia is very urgent, and being not only in that improves anaemia itself,
Also reside in the morbidity and mortality of overall reduction chronic disease.Up to the present, there is not yet it is related Fructus Jujubae extract, red small
The report for combining the application on improving anaemia of beans extract, Fructus Mori extract and Fructus lycii P.E.
Invention content
The purpose of the present invention is overcome the deficiencies of the prior art and provide a kind of body can be promoted to nutrition such as iron and protein
The absorption of substance, so as to improve the functional composition of anaemia.
It is a further object of the present invention to provide the preparation methods of the functional composition.
It is yet another object of the invention to provide the applications of the functional composition.
A kind of functional composition improving anaemia provided by the invention, including following component：Fructus Jujubae extract, rde bean
Extract, Fructus Mori extract and Fructus lycii P.E.
Wherein, Fructus Jujubae extract, warm-natured, sweet in flavor, returns spleen, stomach have tonifying middle-Jiao and Qi and nourishing blood and tranquilization and other effects, can use
It is dirty dry etc. in treatment spleen eating less, weak loose stool and married woman.
Wherein, Semen Phaseoli extract, it is sweet, sour, it puts down, the thoughts of returning home, small intestinl channel, there is inducing diuresis for removing edema and removing toxic substances apocenosis and other effects,
For treating oedema turgor, tinea pedis limb swollen, jaundice, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus and abdominalgia with intestinal abscess etc..
Wherein, Fructus Mori extract, it is sweet, sour, it trembles with fear, the thoughts of returning home, liver and kidney channel have enrich blood enriching yin and fluid dryness and other effects, use
In treatment dizziness and tinnitus, palpitation and insomnia, poliosis, injury thirst, Heat Diabetes and blood deficiency and constipation etc..
Wherein, Fructus lycii P.E, sweet and neutral return liver and kidney channel, have nourishing liver and kidney and benefiting shrewd head and other effects, for controlling
Treat consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis and blurred vision etc..
Preferably, the functional composition provided by the invention for improving anaemia includes the ingredient of following parts by weight：Jujube carries
Take 10-30 parts of 20-50 parts of object, 20-50 parts of Semen Phaseoli extract, 10-30 parts of Fructus Mori extract and Fructus lycii P.E.
It is further preferred that the functional composition provided by the invention for improving anaemia includes the ingredient of following parts by weight：
12-24 parts of 26-38 parts of Fructus Jujubae extract, 25-45 parts of Semen Phaseoli extract, 15-24 parts of Fructus Mori extract and Fructus lycii P.E.
Still further preferably, it is provided by the invention improve anaemia functional composition include following parts by weight at
Point：20 parts of 30 parts of Fructus Jujubae extract, 30 parts of Semen Phaseoli extract, 20 parts of Fructus Mori extract and Fructus lycii P.E.
Still further preferably, it is provided by the invention improve anaemia functional composition include following parts by weight at
Point：10 parts of 30 parts of Fructus Jujubae extract, 40 parts of Semen Phaseoli extract, 20 parts of Fructus Mori extract and Fructus lycii P.E.
In functional composition provided by the present invention：
The Fructus Jujubae extract is the water extract of ripe big date fruit, wherein the content of date polysaccharide is 32-
45wt%, preferably 40wt%.
The Semen Phaseoli extract is the full extract of rde bean mature seed, and withdrawal ratio is preferably 20:1.
The Fructus Mori extract is the water extract of ripe mulberry fruit, wherein the content of anthocyanin is more than 15wt%.
The Fructus lycii P.E is the water extract of ripe fruit of Chinese wolfberry fruit, wherein polysaccharides content is more than
40wt%.
In the above-mentioned technical solutions, the Fructus lycii P.E is that Chaidamu Basin, Qinghai Province produces Qaidam fruit of Chinese wolfberry mellow fruit
Real water extract, wherein polysaccharides content is 42-52wt%, preferably 48.5wt%.
Functional composition provided by the invention further includes pharmaceutically common auxiliary material or complementary ingredient.
The one kind of the dosage form of functional composition provided by the invention in capsule, tablet, electuary, granule.
The present invention provides the preparation methods for the functional composition for improving anaemia, include the following steps：
After mixing by each components in certain proportion, it is 0.1-7wt% to be dried to moisture, is crushed after sterilizing, mistake
80 mesh sieve, in addition pharmaceutically common auxiliary material or complementary ingredient prepare dosage form.
Specifically, it in the drying and sterilization process, is carried out frequently with microwave dryer, controls it in microwave dryer
Stacking thickness be 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C.
The present invention also provides above-mentioned functional compositions or above-mentioned preparation method to prepare food, the drug for improving anaemia
Or the application in health products.
The functional composition of the improvement anaemia of the present invention can increase or reduce according to corresponding ratio in production, such as big
Large-scale production can by kilogram or as unit of ton, small-scale production can also in grams, and weight can increase or reduce,
But the raw material weight proportioning of soup processed constant rate between each composition.
The functional composition that the present invention improves anaemia has the following advantages that：
(1) functional composition provided by the present invention for improving anaemia, which has, promotes body to nutrition such as iron and protein
The function of material absorbing can be very good to improve anaemia, take the purpose that can reach control treatment for a long time；In addition, experimental result
Show that the functional composition has no that apparent toxic effect, edible safety are reliable；
(2) the functional composition raw materials used abundance provided by the present invention for improving anaemia is easy to get, and use
Preparation method can effectively play the effect of each ingredient, and required condition and equipment are simple, simple for process controllable, have highly important
Actual promotional value.
Specific implementation mode
With reference to embodiment, the embodiment of the present invention is furthur described in detail.Following embodiment is used for
Illustrate the present invention, but be not limited to protection scope of the present invention, protection scope of the present invention is subject to claims.
Unless otherwise specified, experiment reagent used in the embodiment of the present invention and material etc. are commercially available, if not having
Body indicates, the conventional means that technological means used in the embodiment of the present invention is well known to the skilled person.
Raw materials used source in the embodiment of the present invention and comparative example：
The Fructus Jujubae extract, the Semen Phaseoli extract, the Fructus Mori extract and the Fructus lycii P.E are purchased
From Xi'an day Biotechnology Ltd..
Wherein：
Fructus Jujubae extract is the water extract of ripe big date fruit, and the content of date polysaccharide is 32-45wt%；
Semen Phaseoli extract is the full extract of rde bean mature seed, and withdrawal ratio is preferably 20:1；
Fructus Mori extract is the water extract of ripe mulberry fruit, and the content of anthocyanin is more than 15wt%；
Fructus lycii P.E is the water extract of ripe fruit of Chinese wolfberry fruit, and polysaccharides content is more than 40wt%.
Embodiment 1：Improve the functional composition of anaemia
1, it forms：Fructus Jujubae extract 30g, Semen Phaseoli extract 30g, Fructus Mori extract 20g, Fructus lycii P.E 20g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Embodiment 2：Improve the functional composition of anaemia
1, it forms：Fructus Jujubae extract 30g, Semen Phaseoli extract 40g, Fructus Mori extract 20g, Fructus lycii P.E 10g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Embodiment 3：Improve the functional composition of anaemia
1, it forms：Fructus Jujubae extract 30g, Semen Phaseoli extract 40g, Fructus Mori extract 15g, Fructus lycii P.E 15g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Embodiment 4：Improve the functional composition of anaemia
1, it forms：Fructus Jujubae extract 45g, Semen Phaseoli extract 25g, Fructus Mori extract 10g, Fructus lycii P.E 20g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Embodiment 5：Improve the functional composition of anaemia
1, it forms：Fructus Jujubae extract 30g, Semen Phaseoli extract 30g, Fructus Mori extract 20g, Fructus lycii P.E 20g；
Wherein, the content of date polysaccharide is 40wt% in Fructus Jujubae extract；Fructus lycii P.E is that the place of production is that Qinghai bavin reaches
The water extract of the ripening fruits of the fruit of Chinese wolfberry of the Qaidam kind of tub real estate, and polysaccharides content is 48.5wt%；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Comparative example 1：
1, it forms：Fructus Jujubae extract 30g, Semen Phaseoli extract 30g, Fructus Mori extract 5g, Fructus lycii P.E 35g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Comparative example 2：
1, it forms：Fructus Jujubae extract 60g, Semen Phaseoli extract 10g, Fructus Mori extract 15g, Fructus lycii P.E 15g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Comparative example 3：
1, it forms：Fructus Jujubae extract 30g, Semen Phaseoli extract 20g, Fructus Mori extract 40g, Fructus lycii P.E 10g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
Comparative example 4：
1, it forms：Fructus Jujubae extract 50g, Fructus Mori extract 25g, Fructus lycii P.E 25g；
2, preparation method：The ingredient of above-mentioned weight proportion is uniformly mixed, is placed in microwave dryer, thickness is stacked in control
For 2-2.5cm, microwave drying and the 4-10min that sterilizes at 60-80 DEG C, the moisture after control drying is less than 7wt%, crushes
Cross 80 mesh sieve to get.
In order to prove beneficial effects of the present invention, the functionality for preparing of the embodiment of the present invention and comparative example is used below
Influence of the composition to the protoporphyrin that dissociates in rat body weight, rat hemoglobin and Rat Erythrocytes is tested, to illustrate the present invention
Effect of the functional composition to improvement anaemia.
1, experiment material
1.1, experimental raw
Functional composition feeding rat prepared by embodiment 1-4 is respectively adopted in experimental example 1-4；
Functional composition feeding rat prepared by comparative example 1-4 is respectively adopted in reference examples 1-4；
1.2, experiment reagent：
Hemoglobinometry kit (HiCN methods):The glad biotechnology research institute of Shanghai section.
1.3, experimental animal：
Male SD Weanling rats, cleaning grade are provided by Hubei Province's Experimental Animal Center.
1.4, laboratory apparatus：
722 type spectrophotometric colorimeters (Shanghai analytical instrument factory)；
The new protoporphyrin analyzer (Kangda Development Co., Guangdong Prov.) of ZNPP-3800 blood.
2, experimental method
Dosage is grouped and given the test agent gives the time
Experiment sets high, medium and low three dosage groups and a negative control group, and experimental group gives a kind of improvement anaemia work(respectively
Energy property food 0.5,1.0,2.0g/kg*d projects (basic, normal, high) gavage, negative control group is with distilled water gavage, 1 time a day, even
Continuous gavage 30d.
2.1, alimentary anemia rat model is established
After selecting health ablactation rat to adapt to 3d under experimental situation, raise stainless with low iron feed and deionized water, use
Steel cage and food tank, the pollution of iron is avoided in experimentation, and since third week, selected part rat adopts tail blood and surveys Hb weekly, directly
When extremely the Hb of most of rats is less than 100g/L, the weight and Hb of whole rats are measured.
2.2, restore experiment
Choose Hb<The rat of 100g/L is randomly divided into as experimental animal according to Anemia in Rats Hb levels and weight
Negative control group and three experimental groups, each group, which continues to raise, to be filled with low iron feed and deionized water, negative control group with distilled water
Stomach, experimental group is respectively with the given the test agent gavage of various dose, continuous gavage.
2.3, hemoglobinometry (cyaniding high ferro-extinction coefficient method)
After continuing gavage 30, weight is measured, femoral artery takes 1 μ l of blood, is put in 25ml cyanmethemoglobin reagent applications
In liquid, mixing, places 15min immediately, and 1.0cm optical path cuvette colorimetrics are used under 540mm wavelength, are returned to zero with reagent blank, will
The OD value of gained sample cell substitutes into formula, calculates hemoglobin concentration.
2.4, Erythrocyte chemokine recepter measures
After continuing gavage 30d, weight is measured, takes the new protoporphyrin analyzer of femoral artery blood ZPP-3800 blood to measure red thin
The free protoporphyrin content of intracellular.
3, experimental result
Data are handled using the variance analysis that mean compares.
The influence of 3.1 pairs of rat body weights
It is as shown in table 1 below be each experimental example of the present invention and reference examples to rat body weight influence comparison table (n
=10).
The influence comparison table of each experimental example of 1 present invention of table and reference examples to rat body weight
As can be seen from the above table, it is obvious but notable compared with the control group to increase rat body for the middle and high dosage group of experimental example
Property less (P>005)；Each dosage group of comparative example compared with the control group, influence to the weight of rat body weight there was no significant difference (P
>005)。
The influence of 3.2 pairs of rat hemoglobins
It is as shown in table 2 below be each experimental example of the present invention and reference examples to rat hemoglobin influence comparison table (N=10).
The influence comparison table of each experimental example of 2 present invention of table and reference examples to rat hemoglobin
Note：Compared with negative control group, △ P<0.01.
As can be seen from the above table, each dosage group of experimental example can dramatically increase rat hemoglobin content, with control group phase
It is more apparent (P than conspicuousness<001)；Each dosage group of comparative example can also increase rat hemoglobin content, compared with the control group without significantly
Sex differernce (P>005).
The influence of free protoporphyrin in 3.3 pairs of Rat Erythrocytes
As shown in table 3 below is the influence result of each experimental example of the present invention and reference examples to the protoporphyrin that dissociates in Rat Erythrocytes
The table of comparisons (N=10).
The influence comparison table of each experimental example of 2 present invention of table and reference examples to rat hemoglobin
Note：Compared with negative control group,△P<0.05,△△P<0.01。
As can be seen from the above table, experimental example high dose group can significantly reduce protoporphyrin content of dissociating in Rat Erythrocytes, with
Control group is compared to conspicuousness significantly (P<001)；Experimental example middle dose group can be substantially reduced in Rat Erythrocytes the protoporphyrin that dissociates and contain
It measures, compared with the control group apparent (the P of conspicuousness<005)；Experimental example low dose group can also reduce the protoporphyrin that dissociates in Rat Erythrocytes
Content, but there was no significant difference compared with the control group (P>005)；Each dosage group of comparative example, which can also write, reduces trip in Rat Erythrocytes
From protoporphyrin content, but there was no significant difference compared with the control group (P>005).
It is above-mentioned experiments have shown that, the functional composition for the improvement anaemia that the embodiment of the present invention is provided can promote body pair
The absorption of the nutriments such as iron, protein, have improves anaemia effect very well.
Finally, above the present invention is described in detail with a general description of the specific embodiments, but
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (10)
1. a kind of functional composition improving anaemia, which is characterized in that include following component：Fructus Jujubae extract, rde bean carry
Take object, Fructus Mori extract and Fructus lycii P.E.
2. functional composition according to claim 1, which is characterized in that include the ingredient of following parts by weight：Jujube carries
Take 10-30 parts of 20-50 parts of object, 20-50 parts of Semen Phaseoli extract, 10-30 parts of Fructus Mori extract and Fructus lycii P.E.
3. functional composition according to claim 2, which is characterized in that include the ingredient of following parts by weight：Jujube carries
Take 12-24 parts of 26-38 parts of object, 25-45 parts of Semen Phaseoli extract, 15-24 parts of Fructus Mori extract and Fructus lycii P.E.
4. functional composition according to claim 3, which is characterized in that include the ingredient of following parts by weight：Jujube carries
Take 20 parts of 30 parts of object, 30 parts of Semen Phaseoli extract, 20 parts of Fructus Mori extract and Fructus lycii P.E.
5. functional composition according to claim 3, which is characterized in that include the ingredient of following parts by weight：Jujube carries
Take 10 parts of 30 parts of object, 40 parts of Semen Phaseoli extract, 20 parts of Fructus Mori extract and Fructus lycii P.E.
6. according to claim 1-5 any one of them functional compositions, which is characterized in that the Fructus Jujubae extract is maturation
The water extract of big date fruit, wherein the content of date polysaccharide is 32-45wt%, preferably 40wt%；
And/or the full extract that the Semen Phaseoli extract is rde bean mature seed, withdrawal ratio is preferably 20:1；
And/or the water extract that the Fructus Mori extract is ripe mulberry fruit, wherein the content of anthocyanin is more than 15wt%；
And/or the water extract that the Fructus lycii P.E is ripe fruit of Chinese wolfberry fruit, wherein polysaccharides content is more than
40wt%.
7. according to claim 1-6 any one of them functional compositions, which is characterized in that the Fructus lycii P.E is blueness
The water extract of extra large Caidamu Basin production Qaidam fruit of Chinese wolfberry ripening fruits, wherein polysaccharides content is 42-52wt%, excellent
It is selected as 48.5wt%.
8. according to claim 1-7 any one of them functional compositions, which is characterized in that further include pharmaceutically common auxiliary
Material or complementary ingredient, the one kind of the dosage form in capsule, tablet, electuary, granule.
9. a kind of preparation method of claim 1-8 any one of them functional compositions, which is characterized in that including walking as follows
Suddenly：
After mixing by each components in certain proportion, it is 0.1-7wt% to be dried to moisture, is crushed after sterilizing, and 80 mesh are crossed
Sieve, in addition pharmaceutically common auxiliary material or complementary ingredient prepare dosage form.
10. the preparation method described in claim 1-8 any one of them functional composition or claim 9 is preparing improvement
Application in the food of anaemia, drug or health products.
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