CN108408170B

CN108408170B - Automatic blood and bag separator

Info

Publication number: CN108408170B
Application number: CN201711457643.9A
Authority: CN
Inventors: 周柏林; 曹希文; 张秋声; 廖晓飞; 陈武; 刘东清; 赵国祥; 易恒亮; 朱少乐
Original assignee: Hengyang Xinshan Mechanical Device Manufacture Co ltd; Nanyue Biopharming Corp ltd
Current assignee: Hengyang Xinshan Mechanical Device Manufacture Co ltd; Nanyue Biopharming Corp ltd
Priority date: 2017-07-04
Filing date: 2017-12-28
Publication date: 2024-05-28
Anticipated expiration: 2037-12-28
Also published as: CN109204983A; CN108408170A

Abstract

An automatic blood and bag separator comprises a workbench, a driving mechanism, a case and a transmission mechanism; the transmission mechanism and the machine case are both positioned above the workbench, the machine case is positioned at the tail end of the transmission mechanism, and a feeding port, a conveying roller mechanism, a squeeze roller and a blood bag discharging port are sequentially arranged in the machine case along the transmission direction; the bag breaking knife is positioned below the conveying roller mechanism, and the plasma discharging port is positioned at the bottom of the machine case; the side surface of the case is also provided with a gear mechanism, and the transmission mechanism, the conveying roller mechanism and the squeeze roller are directly driven by a driving mechanism or indirectly driven by the gear mechanism. By adopting the technical scheme, compared with the prior art, the full-automatic feeding and discharging process is completed automatically, so that time and labor are saved, and the working efficiency is improved by more than one time compared with the prior art; the number of operators who contact with the plasma is reduced from 4 to 0, so that the risk of plasma pollution of the operators in the operation process is greatly reduced, and meanwhile, the bag breaking cost is also reduced; the yield of the plasma is improved from the original 99% to more than 99.4%.

Description

Automatic blood and bag separator

Technical Field

The invention belongs to the field of mechanical equipment, and particularly relates to an automatic blood and bag separator.

Background

The raw material plasma for human serum albumin is healthy human plasma collected by a single plasma collection technique, and the collected plasma is placed in a special bag for plasma, and is required to be frozen and stored below-20 ℃ within 6 hours. After the plasma reaches a certain amount, the preparation can be put into production. Before production, the frozen plasma bags are cut, frozen plasma blocks are extruded, and the frozen plasma blocks are melted for a long time at 37 ℃ in a slurry melting tank.

At present, blood product manufacturers in China all rely on manual operation, and the defects of high labor intensity, low working efficiency, easiness in causing secondary pollution and long slurry melting time are overcome. The patent "a plasma bag automatic cleaning disinfection broken bag combined equipment" (CN2013200522542. X) discloses an equipment integrating functions of cleaning, disinfection, blood and bag separation, and the equipment comprises a conveying mechanism, a bag breaking mechanism and a cleaning mechanism, and has the defects that the structure is too complex, a plasma bag needs to be manually plugged into the equipment, the working efficiency is low, the plasma yield is low, and plasma bag label fragments after breaking pollute the plasma.

Disclosure of Invention

The invention provides an automatic blood and bag separator for solving the problems of excessively complex equipment structure and lower working efficiency in the background technology.

The technical scheme of the invention is as follows: an automatic blood and bag separator comprises a workbench, a driving mechanism, a case and a transmission mechanism; the machine case is installed on the workstation, and transport mechanism end and machine case hookup are equipped with pan feeding mouth, conveying roller mechanism, squeeze roll and blood bag discharge gate in proper order along the transmission direction in the machine case, are equipped with broken bag sword in conveying roller mechanism below, and the machine case bottom is equipped with plasma discharging device, and the machine case side still is equipped with gear mechanism.

The squeeze rollers are arranged up and down, and a gap between the two squeeze rollers is the thickness of an empty plasma bag, so that the plasma in the plasma bag can be squeezed out to the maximum extent.

And an auger is arranged in the plasma discharging device and is used for conveying plasma from the bottom of the case to the plasma melting tank.

The conveying roller mechanism comprises at least two conveying roller groups arranged along the conveying direction, the distance between every two adjacent conveying roller groups and the distance between the last conveying roller group and the squeeze roller are smaller than the length of the plasma bag; each conveying roller group comprises two conveying rollers which are arranged up and down.

Therefore, the distance between two adjacent conveying roller sets and the distance between the last conveying roller set and the squeeze roller are smaller than the length of the plasma bag, so that the plasma bag cannot fall off from between the two adjacent conveying roller sets or between the conveying roller set and the squeeze roller.

The conveying roller mechanism comprises two groups of conveying roller groups which are arranged back and forth along the conveying direction, the distance between the two groups of conveying roller groups and the distance between the next group of conveying roller groups and the squeeze rollers are smaller than the length of the plasma bag, so that the plasma bag is prevented from falling between the two groups of conveying rollers or between the conveying roller groups and the squeeze rollers.

The conveying roller body is cylindrical, and 3-5 edges are uniformly arranged on the surface of the conveying roller body along the axial direction of the conveying roller; a groove matched with the shape of the plasma bag is formed in the middle of each edge along the direction perpendicular to the axis of the conveying roller; the surface of one end of the conveying roller is also provided with a positioning structure. Therefore, the plasma bag is in a bulge state before being broken, and the groove is arranged, so that the plasma bag can be just clamped in the groove.

The reason why the number of the ribs is set to 3 to 5 is that: if the number of the ribs is less than three, the conveying roller mechanism cannot realize the function of clamping and transporting the plasma bags; if the number of the ribs is more than five, the plasma bags are easy to be blocked between the conveying rollers due to inconsistent thickness of the plasma bags, and normal operation of the equipment is affected.

In order to enable the plasma bag to stably move in the horizontal direction when passing through the conveying roller mechanism and smoothly enter the squeeze roller at a correct angle, the edges on the upper conveying roller and the lower conveying roller of the plasma bag cannot be arranged in mirror symmetry by taking the length direction of the plasma bag as a central axis, otherwise, the edges on the upper conveying roller and the lower conveying roller of the plasma bag are opposite to each other, and the included angle is opposite to the included angle, so that the upper and lower stress of the plasma bag in the horizontal transportation process is uneven, and the plasma bag cannot smoothly enter the squeeze roller at the correct angle.

Thus: if the number of the ribs is an odd number, the angles of the ribs on the upper conveying roller and the lower conveying roller in each conveying roller set are always consistent;

If the number of the ribs is an even number, in each conveying roller group, the angle difference of the ribs on the upper conveying roller and the lower conveying roller is 180/N DEG, and N is the number of the ribs; and all the conveying rollers run synchronously.

Three edges are uniformly arranged on the surface of the conveying roller along the axial direction of the conveying roller; the groove is an inverted trapezoid groove; the positioning structure is a positioning hole or a key. The applicant repeated experiments find that the three edges are arranged on the conveying roller as the best scheme, so that the function of conveying the plasma bag can be realized, and the plasma bag can not be blocked.

The diameter of the conveying roller body is 30-40mm; the depth of the groove is 35-45mm, and the maximum width is 65-75mm; the angle of the bevel edge is 150-170 degrees; the cross section contour line of the edge consists of five curves H1, H2, H3, H4 and H5, wherein H1 and H5 are axisymmetric, and H2 and H4 are axisymmetric; h1 and H2 are arcs with the radius of 4-6mm, and H3 is an arc with the diameter of 50-60 mm; the cross-section contour line H6 of the bottom end of the groove is an arc line with the diameter of 40-50 mm.

The transmission mechanism, the conveying roller mechanism and the squeeze roller are directly driven by the driving mechanism or indirectly driven by the gear mechanism.

The invention also provides a method for separating blood plasma by an automatic blood and bag separator, which comprises the following steps:

the first step: the plasma bag is conveyed from the front end to the tail end of the conveying mechanism, enters the machine box from the feeding port and is clamped by the conveying roller mechanism in the machine box;

And a second step of: the plasma bag is scratched by a bag-breaking knife positioned below the conveying roller mechanism in the process of being clamped by the conveying roller mechanism and moving forwards;

and a third step of: the blood plasma bag after being scratched continuously moves forwards to the squeeze roller, and the squeeze roller squeezes the blood plasma bag while continuously transporting the blood plasma bag forwards to squeeze the blood plasma in the blood plasma bag;

Fourth step: the extruded blood plasma falls down to a blood plasma discharging device and is then conveyed to a plasma melting tank for further treatment; the empty plasma bag is transported out through the discharge port of the plasma bag.

By adopting the technical scheme, compared with the prior art, the full-automatic bag breaking machine realizes high-efficiency full-automatic bag breaking, the whole process from feeding to discharging is completed automatically, time and labor are saved, and the working efficiency is improved by more than one time compared with the prior art; the number of operators who contact with the plasma is reduced from 4 to 0, so that the risk of plasma pollution of the operators in the operation process is greatly reduced, and meanwhile, the bag breaking cost is also reduced; the yield of the plasma is improved from the original 99% to more than 99.4%.

The invention separates the blood plasma from the blood plasma bag by using the squeezing mode after the puncturing, so that the label of the blood plasma bag after the puncturing is kept intact without damage, the label is completely prevented from entering the blood plasma tank, the blood plasma tank is prevented from being blocked, and the pollution to the blood plasma by the label is prevented.

The design that sets up the arris on the conveying roller and follow the recess for plasma bag can just block between the conveying roller, ensures moreover that it can follow the steady motion of horizontal direction, gets into the squeeze roll smoothly with correct angle.

Drawings

FIG. 1 is a schematic diagram of the structure of the present invention;

FIG. 2 is a left side view of FIG. 1;

FIG. 3 is a right side view of FIG. 1;

FIG. 4 is a top view of FIG. 1;

FIG. 5 is a cross-sectional view of A-A of FIG. 4;

FIG. 6 is a schematic perspective view of a conveyor roller;

FIG. 7 is a front view of a conveyor roller;

FIG. 8 is a cross-sectional view of B-B of FIG. 7;

FIG. 9 is a cross-sectional view of C-C of FIG. 7;

FIG. 10 is a cross-sectional view of D-D of FIG. 7;

FIG. 11 is a front view of a conveyor roller;

FIG. 12 is a left side view of FIG. 11;

fig. 13 is an enlarged view of a in fig. 12.

In the figure:

1. work bench 11, control panel 12, universal wheel

2. The machine case 21, the working case 22, the gear case 23, the feeding port 24, the squeeze roller 25, the blood bag discharging port 26, the bag breaking knife 27, the tray 28, the plasma discharging device 29 and the auger

3. Transport mechanism 31. Support bracket

4. Conveying roller 41, edge 42, groove 43, positioning hole

51. Motor a 52, motor B53, motor C

6. Plasma bag

221. Transition gear A222, transition gear B223, rolling bag gear set A

224. Rolling bag gear set B225 extrusion bag gear set

Detailed Description

As shown in fig. 1 to 3, an automatic blood and bag separator comprises a workbench 1, a driving mechanism, a machine case 2 and a transmission mechanism 3. The driving mechanism is a motor and is used for driving each component of the equipment; the transmission mechanism 3 and the case 2 are both positioned above the workbench 1, and the case 2 is positioned at the tail end of the transmission mechanism 3; a supporting bracket 31 for supporting the transmission mechanism 3 is arranged below the front end of the transmission mechanism 3, and a motor A51 for driving the transmission mechanism 3 is arranged below the rear end; the workbench 1 is also provided with a control panel 11, and the bottom is provided with a universal wheel 12.

Two independent boxes, namely a working box 21 and a gear box 22 (shown in fig. 4), are arranged in the case 2. The working box 21 is located right in front of the transmission mechanism 3, and the gear box 22 is located on the side of the working box 21. The work box 21 is internally provided with a feed inlet 23, a conveying roller mechanism, a squeeze roller 24 and a blood bag discharge outlet 25 in sequence along the conveying direction, a bag breaking knife 26 is arranged below the conveying roller mechanism, and the blood bag discharge outlet 25 is also provided with a tray 27 (shown in figure 3).

The conveying roller mechanism comprises two conveying roller sets which are arranged back and forth along the conveying direction, the distance between the two conveying roller sets is smaller than the length of the plasma bag, and each conveying roller set consists of two conveying rollers 4 which are arranged up and down (as shown in fig. 3). The body of the conveying roller 4 is cylindrical, and three ribs 41 are uniformly arranged on the surface of the conveying roller along the direction of the conveying roller. Because the plasma bags are in a bulge state before being broken, the middle part of each rib 41 is provided with an inverted trapezoid groove 42 along the direction of the conveying roller, so that the plasma bags can be just clamped in the grooves 42; the surface of one end of the conveying roller 4 is also provided with a positioning hole 43. To ensure that the blood bag 6 remains moving horizontally as it passes over the conveyor roller mechanism and enters the squeeze roller 24 smoothly at the correct angle, the four conveyor rollers 4 must run synchronously with the angle of the ribs 41 on both the upper and lower conveyor rollers 4 of each conveyor roller set remaining the same (as shown in fig. 7).

As shown in fig. 11, the diameter D of the body of the conveying roller 4 is 35mm; the depth L1 of the groove 42 is 40mm, the maximum width L270mm, and the angle θ of the oblique side is 170 °.

As shown in fig. 13, the cross-sectional profile of the rib 41 is composed of five curves H1, H2, H3, H4, and H5, wherein H1 is axisymmetric with H5, and H2 is axisymmetric with H4; h1 and H2 are arcs with the radius of 5mm, and H3 is an arc with the diameter of 56 mm; the cross-sectional profile line H6 of the bottom of the groove 42 is an arc shape having a diameter of 44 mm.

As shown in fig. 3, two squeeze rollers 24 are provided, and the two squeeze rollers 24 are arranged up and down, and the gap is the thickness of an empty plasma bag, so as to ensure that the plasma in the plasma bag can be squeezed out to the maximum extent.

As shown in fig. 3, a plasma discharging device 28 is arranged at the bottom side of the chassis 2, a packing auger 29 is arranged in the plasma discharging device 28 and is used for conveying plasma from the bottom of the chassis to the plasma melting tank, and the packing auger 29 is driven by a motor B52.

As shown in fig. 5, a transition gear a221, a transition gear B222, a rolling bag gear set a223, a rolling bag gear set B224 and a squeezing bag gear set 225 are arranged in the gear box 22; the transition gear B222 is meshed with the extrusion bag gear set 225 and the rolling bag gear set B224, and when the extrusion bag gear set 225 rotates, the transition gear B222 is driven to rotate, so that the rolling bag gear set B224 is driven to rotate; the transition gear A221 is meshed with the rolling bag gear set B224 and the rolling bag gear set A223, and when the rolling bag gear set B224 rotates, the transition gear A221 is driven to rotate, and then the rolling bag gear set A223 is driven to rotate; the rolling bag gear set A223 and the rolling bag gear set B224 are respectively connected with the front conveying roller set and the rear conveying roller set, and the extrusion bag gear set 225 is connected with the extrusion roller 24; the motor C53 is connected to the squeeze bag gear 225 via a motor shaft for driving the conveying roller 4 and the squeeze roller 24.

In operation, as shown in fig. 3 and 4, first, the plasma bag 6 is transported from the front end to the distal end of the transport mechanism 3, enters the work box 21 through the inlet 23, and is held by the transport roller mechanism. The plasma bag 6 is scratched by a bag-breaking knife 26 positioned below the conveying roller mechanism in the process of being clamped by the conveying roller mechanism and moving forwards, and then the plasma bag is continuously moved forwards to a squeeze roller 24, the squeeze roller 24 squeezes the plasma bag 6 while continuously transporting the plasma bag 6 forwards, so that the plasma in the plasma bag 6 is squeezed out, the squeezed plasma drops downwards to a plasma discharging device 28, and then is transported to a plasma melting tank by an auger 29 for further treatment; the empty plasma bag 6 is then transported out through the plasma bag outlet 25 into the tray 27 for collection.

The present invention is not limited to the above-described preferred embodiments, and any person who can learn the structural changes made in the light of the present invention should fall within the scope of the present invention, even if the present invention has the same or similar technical solutions.

Claims

1. An automatic blood and bag separator, which is characterized in that: comprises a workbench, a driving mechanism, a case and a transmission mechanism; the machine case is arranged on the workbench, the tail end of the transmission mechanism is connected with the machine case, a feeding port, a conveying roller mechanism, a squeeze roller and a blood bag discharging port are sequentially arranged in the machine case along the transmission direction, a bag breaking knife is arranged below the conveying roller mechanism, a plasma discharging device is arranged at the bottom of the machine case, and a gear mechanism is further arranged on the side face of the machine case;

The conveying roller mechanism comprises at least two conveying roller groups arranged along the conveying direction, and each conveying roller group comprises two conveying rollers arranged up and down; the conveying roller is cylindrical, 3-5 edges are uniformly arranged on the surface of the conveying roller along the axial direction of the conveying roller, a groove matched with the shape of the plasma bag is formed in the middle of each edge along the direction perpendicular to the axial direction of the conveying roller, and the depth of the groove is smaller than the height of the edge;

All conveying rollers run synchronously; if the number of the ribs is an odd number, the angles of the ribs on the upper conveying roller and the lower conveying roller in each conveying roller set are always consistent; if the number of the ribs is even, the angles of the ribs on the upper conveying roller and the lower conveying roller in each conveying roller set are different by (180/N) °, and N is the number of the ribs.

2. The automatic blood and bag separator according to claim 1, wherein: the squeeze rollers are arranged up and down, and the gap between the two squeeze rollers is the thickness of an empty plasma bag.

3. The automatic blood and bag separator according to claim 1, wherein: an auger is arranged in the plasma discharging device.

4. An automatic blood bag separator according to any one of claims 1-3, wherein: the distance between two adjacent conveying roller sets and the distance between the last conveying roller set and the squeeze roller are smaller than the length of the plasma bag.

5. The automatic blood and bag separator according to claim 4, wherein: the conveying roller mechanism comprises two groups of conveying roller groups which are arranged back and forth along the conveying direction, the distance between the two groups of conveying roller groups and the distance between the next group of conveying roller groups and the squeeze rollers are smaller than the length of the plasma bag.

6. The automatic blood and bag separator according to claim 4, wherein: the surface of one end of the conveying roller is provided with a positioning structure.

7. The automatic blood and bag separator according to claim 6, wherein: the surface of the conveying roller is uniformly provided with 3 edges along the axial direction of the conveying roller; the groove is an inverted trapezoid groove; the positioning structure is a positioning hole or a key.

8. The automatic blood and bag separator according to claim 7, wherein: the diameter of the conveying roller body is 30-40mm; the depth of the groove is 35-45mm, and the maximum width is 65-75mm; the angle of the bevel edge is 150-170 degrees; the cross section contour line of the edge consists of five curves H1, H2, H3, H4 and H5, wherein H1 and H5 are axisymmetric, and H2 and H4 are axisymmetric; h1 and H2 are arcs with the radius of 4-6mm, and H3 is an arc with the diameter of 50-60 mm; the cross-section contour line H6 of the bottom end of the groove is an arc line with the diameter of 40-50 mm.

9. A method of separating plasma using the automatic blood and bag separator of any one of claims 1-8, comprising the steps of: