CN108404050A - A kind of herbal mixture drink that prevention brain is degenerated - Google Patents

A kind of herbal mixture drink that prevention brain is degenerated Download PDF

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Publication number
CN108404050A
CN108404050A CN201810418214.9A CN201810418214A CN108404050A CN 108404050 A CN108404050 A CN 108404050A CN 201810418214 A CN201810418214 A CN 201810418214A CN 108404050 A CN108404050 A CN 108404050A
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parts
drink
radix
degenerated
herbal mixture
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刘政阳
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Hunan Precision Food Technology Co Ltd
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Hunan Precision Food Technology Co Ltd
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
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    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The present invention relates to a kind of herbal mixture drinks that prevention brain is degenerated, it is made of the raw material of following parts by weight:3 20 parts of 3 20 parts of astragalus root, 3 20 parts of Radix Codonopsis, 3 20 parts of radix rehmanniae preparata, 16 parts of g of Rhizoma Chuanxiong, 3 20 parts of sealwort, 3 20 parts of Poria cocos, 3 20 parts of Rhizoma Atractylodis Macrocephalae, 2 10 parts of fructus amomi, 2 10 parts of Radix Polygalae, 2 12 parts of dried orange peel, 3 20 parts of grass-leaved sweetflag, 3 20 parts of fructus alpiniae oxyphyllae, 3 20 parts of Semen Cuscutae, 3 20 parts of Herba Cistanches, 3 20 parts of the fruit of Chinese wolfberry and Radix Curcumae.The present invention foundes the party according to traditional Chinese medicine " the five internal organs god " is theoretical, with kidney tonifying marrow facilitating, strengthening the spleen and reducing phlegm, inducing resuscitation of having one's ideas straightened out and other effects, it is applicable to occur that memory function obviously declines, intelligence decline, counting loss, speech are reduced, looked dull, the slack prevention for thinking the brains degradation phenomenas such as sleeping, tooth Song Fajiao, waist soreness, dizziness and tinnitus.The present invention can be made into liquid, solid or soft drink, and wide application of the crowd, mouthfeel and product form are more humane.

Description

A kind of herbal mixture drink that prevention brain is degenerated
Technical field
The present invention relates to herbal mixture fields, refer in particular to a kind of herbal mixture drink that prevention brain is degenerated.
Background technology
Brain degeneration, also known as Alzheimer disease, dementia are one group of performances with disturbance of intelligence, physiological function decline, pathology Morphologic change, the brain tissue damage disease that biochemical metabolism disorder is characterized.Traditional Chinese medicine category " dementia ", " text silly ", " forgetful ", " depressive psychosis ", " strongly fragrant disease ", " dementia ", " not intelligent ", " imbecility " ... wait scopes.The research of Chinese medicine traditional theory thinks that dementia is with " fan It is puzzled forgetful ", " speech kind miss ", " unconnected phrase ", " slack reposal ", a series of insanity symptoms such as " bitter sorrow is sad " be main feature Progressive wasting conditions, the past doctor is mostly with deficient argument, and anti-Zhiduo County is based on qi-restoratives.However thought according to current research, Dull-witted formation is on the basis of kidney channel virtual loss, is made in human-body viscera function imbalance, phlegm-blood stasis, changes hot air wind producing, wind fire phlegm-blood stasis folder It is miscellaneous, on disturb brain key, accumulateing with the passing of time, turn to that turbid poison, hindering network, to lose marrow, refreshing machine impaired to which hair is dementia.And such existing prevention Property drug without based on this, it is not especially desirable to carry out research and compatibility, control effect.
Invention content
The purpose of the present invention is being directed to disadvantage present in background technology and problem to be improved and innovated, provide a kind of anti- Control the herbal mixture drink of brain degeneration.
The present invention is made of the raw material of following parts by weight:3-20 parts of astragalus root, 3-20 parts of Radix Codonopsis, 3-20 parts of radix rehmanniae preparata, Rhizoma Chuanxiong 1-6 parts of g, 3-20 parts of sealwort, 3-20 parts of Poria cocos, 3-20 parts of Rhizoma Atractylodis Macrocephalae, 2-10 parts of fructus amomi, 2-10 parts of Radix Polygalae, 2-12 parts of dried orange peel, stone Chang 3-20 parts of 3-20 parts of Pu, 3-20 parts of fructus alpiniae oxyphyllae, 3-20 parts of Semen Cuscutae, 3-20 parts of Herba Cistanches, 3-20 parts of the fruit of Chinese wolfberry and Radix Curcumae.
The optimum amount parts by weight of each raw material of the present invention are:10 parts of astragalus root, 10 parts of Radix Codonopsis, 10 parts of radix rehmanniae preparata, 3 parts of Rhizoma Chuanxiong, 10 parts of sealwort, 10 parts of Poria cocos, 10 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of fructus amomi, 5 parts of Radix Polygalae, 6 parts of dried orange peel, 10 parts of grass-leaved sweetflag, 10 parts, Tu of fructus alpiniae oxyphyllae 10 parts of 10 parts of son, 10 parts of Herba Cistanches, 10 parts of the fruit of Chinese wolfberry and Radix Curcumae.
Preferably, the raw material of each parts by weight is the prepared slices of Chinese crude drugs.
Liquid beverage is made in the drink in one of the embodiments,.
Pouring type solid beverage is made in the drink in one of the embodiments,.
Soft drink is made in the drink in one of the embodiments,.
Advantages of the present invention and advantageous effect:
The present invention has kidney tonifying marrow facilitating, strengthening the spleen and reducing phlegm, inducing resuscitation of having one's ideas straightened out and other effects, be applicable to occur memory function obviously decline, Intelligence decline, counting loss, speech is reduced, is looked dull, the brains such as think of sleeping, tooth Song Fajiao, waist soreness, dizziness and tinnitus of slacking off move back Change the prevention of phenomenon.The present invention can be made into liquid, solid or soft drink, and wide application of the crowd, mouthfeel and product form are more humane.
It is dull-witted(Encephalopathy)It is a kind of specific manifestation of systemic disease, sick position is in brain, and morbidity all has relationship with the five internal organs. The lesion of Chinese medicine the five internal organs " god " is then the Main Etiological Factors of encephalopathy.Chinese medicine the five internal organs " god " are using the vital essence of human five internal organs as substance Basis, performance not only in terms of the state of mind of human body, is also demonstrated by the various functions activity of the five internal organs.The change of the five internal organs " god " Change the functional activity of the function or even human limb bones of the body collectively that influence whether human five internal organs, and the prosperity and decline of human internal organ directly affects The activity of " god " is arrived.
Chinese medicine thinks that brain is the internal organs of first god, and god's leads, institute's disease of the movable external manifestation god of owner's body all life, Beginning of all kinds of diseases and ailments, the controlling of god, first wake up its god.Therefore encephalopathy patient can reflect the weight of disease from its spirit, mind, manner, Entire disease occurs, development and prognosis during hold on to " god " and controlled to discuss, had one's ideas straightened out with inducing resuscitation based on.The present invention selects stone Calamus, Radix Polygalae, fructus alpiniae oxyphyllae compatibility, to solve above-mentioned illness.
It is dull-witted closely related with the five internal organs, it is that the five internal organs vital essence decays, phlegm is turbid, hemostasis blocks brain key and causes clear key to be covered, refreshing machine Appraxia, carried out by brains do not fill.Heart governing blood and vessels, main mind, blood are the movable material bases of mind, if the mind loses moistening in painstaking effort It supports, the dysfunction of heart governing blood and vessels.Necessarily lead to the movable abnormal change of mind, the heart dominate the spirit of people, consciousness, thinking, The activities such as memory, deficiency of heart-QI, blood-vessel obstructive, have ants in one's pants, will appear it is grieved more than, laugh endlessly, fill blood, adjust god's machine to be Its big method.The present invention selects astragalus root, Radix Codonopsis, radix rehmanniae preparata, sealwort compatibility, to solve above-mentioned illness.
If liver master dredge rush down, it is logical without it is stagnant, dissipate lost without strongly fragrant, liver dredge rush down, feelings will is unsuccessful, stagnation of liver qi, first easyization burn It is cloudy;Second qi stagnation hemagglutination, obstruction brain key, dysfunction of YANG-orifices are looked dull, therefore preferably bleed soothing liver-qi stagnation.The present invention selects Radix Curcumae, river Rhizome of chuanxiong, fructus amomi compatibility, to solve above-mentioned illness.
The spleen being the foundation of acquired constitution, source of generating QI and blood, the personal vital organs of the human body are all bad to be supported, taste virtual loss, dysfunction of the spleen in transportation and transformation, day It can make that qi and blood essence body fluid deficiency is empty, is lost without the above flourish brain, gods and supports and be silly long, The spleen has the function to transport and transform nutrients, and water is wet, spleen deficiency transporting mistake department, and water is wet Inside stop, gather and be phlegm, upper to violate clear key be then dull-witted, lung controlling dispersing outward and inwards, regulating fluid apssage, the aqueous in human body by transporting and transforming function of the spleen and stomach and Come, the defeated cloth of aqueous, operation and row are rushed down, and the dredging for again relying on lung is adjusted, to maintain dynamic equilibrium.If lung governing regulation of water passages Dysfunction, cannot defeated cloth aqueous, then water is wet stops gathering, consor phlegm and retained fluid, phlegm is turbid or convulsive seizure due to phlegm-fire on disturb, cover and close clear key and cause dementia, Strengthening the spleen and stomach, tonifying lung gas eliminating the phlegm is turbid holds back the source of producing phlegm, and the clear device for storing phlegm is the sheet that it is controlled.The present invention selects astragalus root, Radix Codonopsis, Fu Siberian cocklebur, dried orange peel, Rhizoma Atractylodis Macrocephalae compatibility, to solve above-mentioned illness.
The relationship of kidney and brain is extremely close.Brain it is main spirit, consciousness, people's thinking activities material base be kidney essense institute metaplasia Brains, " the brain being the reservoir of the marrow ", kidney storing essence, essence can give birth to marrow, gather in brain on marrow, therefore kidney essense is sufficient, the main intelligency activity of excess of marrow-reservoir brain Function can just give full play to, conversely, with the increase at age, the aging of body, essence in kidney also increasingly virtual loss.Brain is lost Fill, god becomes homeless foster, therefore see Memory Impairment, disturbance of intelligence, the smart indifferent hair of feelings is dementia, therefore kidney tonifying marrow facilitating is big method.This Radix rehmanniae preparata, matrimony vine, Semen Cuscutae, Herba Cistanches compatibility are selected in invention, to solve above-mentioned illness.
The present invention foundes the party according to traditional Chinese medicine " the five internal organs god " is theoretical, is targetedly closed to the organic factor for causing brain to degenerate Compatibility is managed, then by the synergistic effect between each compatibility raw material, brain degenerating disorders can be effectively prevented and treated.
Specific implementation mode
It is of the invention for ease of understanding, several embodiments of the present invention are shown below.But the present invention can be with many not With form realize, however it is not limited to embodiment described herein.Make to this on the contrary, purpose of providing these embodiments is The disclosure of invention is more thorough and comprehensive.
Unless otherwise defined, the skill of all technical and scientific terms used herein and the technical field of the present invention The normally understood meaning of art personnel is identical.Term used in the description is intended merely to describe specifically to implement purpose, is not It is intended to the limitation present invention.
Embodiment 1:
Take prepared slices of Chinese crude drugs astragalus root 10g, Radix Codonopsis 10g, radix rehmanniae preparata 10g, Rhizoma Chuanxiong 3g, sealwort 10g, Poria cocos 10g, Rhizoma Atractylodis Macrocephalae 10g, fructus amomi 5g, Radix Polygalae 5g, dried orange peel 6g, grass-leaved sweetflag 10g, fructus alpiniae oxyphyllae 10g, Semen Cuscutae 10g, Herba Cistanches 10g, fruit of Chinese wolfberry 10g, Radix Curcumae 10g, it is standby With.
Using existing Chinese patent drug processing technology, by extraction, filtering, concentration, refined, recycling solvent, granulation, drying, most Powdered this product is distributed into the herbal mixture solid beverage that prevention brain is degenerated afterwards, brews and takes.
Embodiment 2:
Take prepared slices of Chinese crude drugs astragalus root 3g, Radix Codonopsis 3g, radix rehmanniae preparata 3g, Rhizoma Chuanxiong 1g, sealwort 3g, Poria cocos 3g, Rhizoma Atractylodis Macrocephalae 3g, fructus amomi 2g, Radix Polygalae 2g, dried orange peel 2g, grass-leaved sweetflag 3g, fructus alpiniae oxyphyllae 3g, Semen Cuscutae 3g, Herba Cistanches 3g, fruit of Chinese wolfberry 3g, Radix Curcumae 3g, it is spare.
Using existing Chinese patent drug processing technology, by extraction, filtering, concentration, refine, after finally recycling solvent, by liquid The herbal mixture beverage of this prevention brain degeneration is made in beverage standard.
Embodiment 3:
Take prepared slices of Chinese crude drugs astragalus root 20g, Radix Codonopsis 20g, radix rehmanniae preparata 20g, Rhizoma Chuanxiong 6g, sealwort 20g, Poria cocos 20g, Rhizoma Atractylodis Macrocephalae 20g, fructus amomi 10g, Radix Polygalae 10g, dried orange peel 12g, grass-leaved sweetflag 20g, fructus alpiniae oxyphyllae 20g, Semen Cuscutae 20g, Herba Cistanches 20g, fruit of Chinese wolfberry 20g, Radix Curcumae 20g, it is spare.
Soft drink is finally pressed by extraction, filtering, concentration, refined, recycling solvent using existing Chinese patent drug processing technology It is required that the herbal mixture soft drink that the degeneration of this prevention brain is made in corresponding raw material is added.
Embodiment 4:
Take prepared slices of Chinese crude drugs astragalus root 15g, Radix Codonopsis 15g, radix rehmanniae preparata 15g, Rhizoma Chuanxiong 5g, sealwort 15g, Poria cocos 15g, Rhizoma Atractylodis Macrocephalae 15g, fructus amomi 6g, Radix Polygalae 6g, dried orange peel 10g, grass-leaved sweetflag 15g, fructus alpiniae oxyphyllae 15g, Semen Cuscutae 15g, Herba Cistanches 15g, fruit of Chinese wolfberry 15g, Radix Curcumae 15g, It is spare.
Using existing Chinese patent drug processing technology, by extraction, filtering, concentration, refine, after finally recycling solvent, by liquid The herbal mixture beverage of this prevention brain degeneration is made in beverage standard.
Embodiment 5:
Take prepared slices of Chinese crude drugs astragalus root 12g, Radix Codonopsis 12g, radix rehmanniae preparata 12g, Rhizoma Chuanxiong 1g, sealwort 12g, Poria cocos 12g, Rhizoma Atractylodis Macrocephalae 12g, fructus amomi 9g, Radix Polygalae 9g, dried orange peel 5g, grass-leaved sweetflag 12g, fructus alpiniae oxyphyllae 12g, Semen Cuscutae 12g, Herba Cistanches 12g, fruit of Chinese wolfberry 12g, Radix Curcumae 12g, it is standby With.
Using existing Chinese patent drug processing technology, by extraction, filtering, concentration, refined, recycling solvent, granulation, drying, most Powdered this product is distributed into the herbal mixture solid beverage that prevention brain is degenerated afterwards, brews and takes.
The present invention is using pure Chinese herbal medicine as raw material, based on Chinese medicine study, compares existing Western medicine prevention brain degeneration, A Er Ci Haimo diseases, dementia effect become apparent from, less side effects.
1, the mechanism subordinate act of Chinese herb prevention AD (Alzheimer ' s disease, Alzheimer disease) is inquired at many levels , morphology, neurotransmitter, energetic supersession, nerve cell apoptosis and molecular biology angle inquire into AD pathogenesis and Chinese medicine Mechanism of action.
In terms of morphology:Chinese medicine compound prescription can improve infraction ischemic after nerve ultra microstructure change, have guarantor to neuron Shield acts on.
In terms of behaviouristics:Chinese medicine compound prescription can not only improve MID model mouses and left cortical blood vessel dementia-like model is gone to decline Ability of learning and memory, and memory retention can be remarkably reinforced in preoperative administration.
In terms of neurotransmitter adjusting:Chinese medicine compound prescription has to adjust to MID rat models cortex and hippocampus Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 content to be made With.To MID(For Multi-infarct dementia)Rat model cortex and hippocampus excitatory amino acids content have adjustment effect, can be improved MID rat models cortex and the dopamine at hippocampus position, the Noradrenaline Contents of adrenaline and hippocampus position, and drop The content of low above-mentioned two positions, 50 hydroxytryptamine can improve the red cell deformability of MID rats, increase the brain blood declined after MID Flow.Chinese medicine compound prescription can obviously improve the positions such as cortex, hippocampus, the Mtyhtrt basal nucleis of cortex blood vessel dementi-a mimetic and go out Existing acetylcholinesterase fibre modification is downright bad, white under retrograde degeneration and severe ischemic denaturation and thalamus, hypothalamus, cortex The ischemic injuries of the multiple locations such as matter.After compound of Chinese herbal medicine goes cortex dementia-like model mouse, astroglia is to injury repair Ability enhancing, iron ion accumulation reduce, less toxic, nitric oxide synthesis increase.
In addition, carrying out Cell. Mol with the legal Healthy People embryo brain N cells of 13 week old of in vitro culture studies table Bright, Chinese medicine compound prescription is lossless to people's embryo brain N cells under regular culture conditions injures toxic action, under anoxic condition of culture, Chinese medicine Compound has protective effect to people's embryo brain N cellular damages.
2, curative effect determinate standard reference《The dull-witted guideline of clinical investigations of new Chinese medicine treatment》Total effective rate 84.3%, With western medicine group than effect #P < 0.5.
Using mini-mental state examination table(MMSE), Blessecl behavior rating scales(BBS), comparison medicine crowd recognize work( Energy, intelligence Asia item, capacity, capacity Asia item are evaluated, and as a result prove that Chinese medicine compound prescription can significantly improve MMSE integrals, BBS integrals are reduced, have improvement to make disturbance of intelligence core symptom useful, are also had to the decline of functional activity ability caused by disturbance of intelligence Have an improvement result, but also with it is substantially reduced or eliminate headache, tinnitus, tongue fiber crops, dribble of urine, just dry just hardly possible, limbs arrested anxious, It takes out that Xu, numb in every limb, four limbs are last the peripheral symptoms such as send out cool, is excellent compared with Western medicine group.
Embodiment of the present invention is only the description carried out to the preferred embodiment of the present invention, not to the present invention Conception and scope is defined, and under the premise of not departing from design philosophy of the present invention, engineers and technicians are to this hair in this field The all variations and modifications that bright technical solution is made should all fall into protection scope of the present invention, the claimed skill of the present invention Art content has all been recorded in detail in the claims.

Claims (6)

1. a kind of herbal mixture drink that prevention brain is degenerated, it is characterised in that it is made of the raw material of following parts by weight:
3-20 parts of astragalus root, 3-20 parts of Radix Codonopsis, 3-20 parts of radix rehmanniae preparata, 1-6 parts of g of Rhizoma Chuanxiong, 3-20 parts of sealwort, 3-20 parts of Poria cocos, Rhizoma Atractylodis Macrocephalae 3-20 parts, 2-10 parts of fructus amomi, 2-10 parts of Radix Polygalae, 2-12 parts of dried orange peel, 3-20 parts of grass-leaved sweetflag, 3-20 parts of fructus alpiniae oxyphyllae, Semen Cuscutae 3-20 3-20 parts of part, 3-20 parts of Herba Cistanches, 3-20 parts of the fruit of Chinese wolfberry and Radix Curcumae.
2. the herbal mixture drink that prevention brain according to claim 1 is degenerated, it is characterised in that the raw material of following parts by weight It is made:
10 parts of astragalus root, 10 parts of Radix Codonopsis, 10 parts of radix rehmanniae preparata, 3 parts of Rhizoma Chuanxiong, 10 parts of sealwort, 10 parts of Poria cocos, 10 parts of Rhizoma Atractylodis Macrocephalae, 5 parts of fructus amomi, 5 parts of Radix Polygalae, 6 parts of dried orange peel, 10 parts of grass-leaved sweetflag, 10 parts of fructus alpiniae oxyphyllae, 10 parts of Semen Cuscutae, 10 parts of Herba Cistanches, 10 parts of the fruit of Chinese wolfberry and Radix Curcumae 10 parts.
3. the herbal mixture drink that prevention brain according to claim 1 is degenerated, it is characterised in that each parts by weight Raw material is the prepared slices of Chinese crude drugs.
4. the herbal mixture drink that prevention brain according to claim 1 is degenerated, it is characterised in that the drink is liquid beverage.
5. the herbal mixture drink that prevention brain according to claim 1 is degenerated, it is characterised in that the drink is solid for pouring type Body beverage.
6. the herbal mixture drink that prevention brain according to claim 1 is degenerated, it is characterised in that the drink is soft drink.
CN201810418214.9A 2018-05-04 2018-05-04 A kind of herbal mixture drink that prevention brain is degenerated Pending CN108404050A (en)

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CN108057108A (en) * 2017-12-12 2018-05-22 广州香象渡河生物科技有限公司 A kind of Chinese medicine health-care perfume (or spice) and preparation method thereof
CN110934997A (en) * 2019-12-19 2020-03-31 广西中医药大学第一附属医院 Composition for treating moderate dementia, preparation and application thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108057108A (en) * 2017-12-12 2018-05-22 广州香象渡河生物科技有限公司 A kind of Chinese medicine health-care perfume (or spice) and preparation method thereof
CN110934997A (en) * 2019-12-19 2020-03-31 广西中医药大学第一附属医院 Composition for treating moderate dementia, preparation and application thereof

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Application publication date: 20180817