CN108379135A - The composition and its extraction process of a kind of purple sesame extract and application - Google Patents
The composition and its extraction process of a kind of purple sesame extract and application Download PDFInfo
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- CN108379135A CN108379135A CN201810372932.7A CN201810372932A CN108379135A CN 108379135 A CN108379135 A CN 108379135A CN 201810372932 A CN201810372932 A CN 201810372932A CN 108379135 A CN108379135 A CN 108379135A
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- purple sesame
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- extraction
- sesame extract
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Abstract
The present invention provides a kind of composition of purple sesame extract and its extraction process and applications；The composition includes water phase purple sesame extract and oil phase purple sesame extract；Wherein, the parts by weight of the water phase purple sesame extract are 0.5 15 parts, and the parts by weight of the oil phase purple sesame extract are 0.1 5 parts；The present invention passes through Optimized Extraction Process, the maximized essential ingredient extracted in purple sesame, and it is water phase and oil-phased extract is reasonably combined, obtained composition is added in cosmetics, two kinds of components can modify skin under specific proportioning and play apparent anti-aging effects, have broad application prospects and huge market value；Present invention process is simple, it can be achieved that industrialization large-scale production, can be that enterprise brings good economic benefit, have wide foreground.
Description
Technical field
The present invention relates to cosmetic field, relates generally to a kind of composition of purple sesame extract and its extraction process and answer
With.
Background technology
Modern science proves that the ganoderma lucidum rare fungus medicinal material traditional as China has extensive pharmacological action and a variety of guarantors
Strong value, the ingredient separated from ganoderma lucidum at present is more than 150 kinds, and main physiological activator is polysaccharide, triterpene
Class, grease type, protide, alkaloids, sterols etc., especially ganoderma lucidum polysaccharide and ganoderma lucidum spore oil have antitumor, immune
Adjusting, anti-oxidant, anti-aging, anti-inflammatory and reducing blood sugar and blood lipid is with a wide range of features is favored, are widely used in food, drug and health products
In.Purple sesame is one kind of ganoderma lucidum,《Sheng Nong's herbal classic》Purple sesame is classified as the top grade in ganoderma lucidum, anti-ageing and health maintenance effect is also
It is most significant in ganoderma lucidum.
Chinese invention patent application number 201711061167.9, it is entitled " a kind of to contain the anti-ageing of Ganodenna Lucidum P.E
Always, net white composition and preparation method thereof " discloses a kind of anti-apolexis composition containing ganoderma lucidum, and the composition has certain
Anti-ageing and whitening effect, but the extraction composition causes raw material there is no maximization is rationally utilized the effect of ganoderma lucidum raw material
Waste.Chinese invention patent application number 201410219028.4, entitled " a kind of ganoderma lucidum anti-aging face cream and its preparation
Method " discloses a kind of preparation of anti-aging face cream, which has used water extraction and supercritical CO respectively2Extraction has area
Other essential ingredient extracted in ganoderma lucidum, but the recovery rate of both modes is not high, it can not be effectively sharp by ganoderma lucidum essence
With.
In conclusion the prior art is not perfect to the extraction process and application mode of purple sesame extract, it is to be improved, because
This, it is added in cosmetics and is carried with playing purple sesame by the technique for researching and developing the active ingredient in a kind of high efficiency extraction purple sesame in right amount
The effect of taking object, has broad application prospects and market value.
Invention content
In view of the deficiencies of the prior art with the demand in market, the present invention provides a kind of composition of purple sesame extract and its
Extraction process and application maximumlly extract the essential ingredient in purple sesame by Optimized Extraction Process, and by water phase and oil phase
Extract is reasonably combined, and obtained composition is added in cosmetics, and apparent anti-aging effect is played while modifying skin
Fruit has broad application prospects and huge market value.
In a first aspect, the present invention provides a kind of composition of purple sesame extract, the composition is extracted comprising water phase purple sesame
Object and oil phase purple sesame extract；
Wherein, the parts by weight of the oil phase purple sesame extract are 0.1-5 parts, the parts by weight of the water phase purple sesame extract
Number is 0.5-15 parts.
In the present invention, inventor can deeply slow down aging in excavation traditional Chinese medicine in long-term production research process
Effective type searches out the purple sesame the most significant of anti-ageing health maintenance effect in ganoderma lucidum and makees using rare fungus medicinal material ganoderma lucidum as starting point
For the extraction raw material of anti-ageing active component, oil phase spore oil and water phase ganoderma lucidum polysaccharide are extracted respectively, two kinds of extracts of optimization
Component proportion finds that the two mutually collaboration plays remarkable senile-resistant efficacy under said ratio.
Preferably, the parts by weight of the oil phase purple sesame extract are 0.1-5 parts, for example, can be 0.1 part, 0.5 part, 1
Part, 2 parts, 3 parts, 4 parts or 5 parts.
Preferably, the parts by weight of the water phase purple sesame extract are 0.5-15 parts, for example, can be 0.5 part, 1 part, 2
Part, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or 15 parts.
Second aspect, the present invention provide a kind of method for extracting water phase purple sesame extract as described in relation to the first aspect, including such as
Lower step：
(1) it pre-processes：Purple sesame fructification is taken, it is for use after pulverizing and sieving；
(2) alcohol reflux：The powder that step (1) obtains is added in ethyl alcohol and carries out refluxing extraction, centrifugation obtains precipitating simultaneously
It is dry；
(3) ultrasonic extraction：The powder that step (2) obtains is added to the water carry out ultrasonic extraction, centrifugation removal is dense after precipitating
Contracting filtrate to the weight ratio of filtrate and initial purple sesame powder is 1:(1-10) obtains water phase purple sesame extract.
Preferably, the mesh number of step (1) described sieving be 20-100 mesh, such as can be 20 mesh, 30 mesh, 40 mesh, 50 mesh,
60 mesh, 70 mesh, 80 mesh, 90 mesh or 100 mesh.
Preferably, the volumetric concentration of step (2) described ethyl alcohol is 50-95%, for example, can be 50%, 60%, 70%,
80%, 90% or 95%.
Preferably, the solid-liquid ratio of step (2) described refluxing extraction is 1:(1-10), such as can be 1:1、1:3、1:5、1:
7、1:9 or 1:10.
Preferably, the temperature of step (2) described refluxing extraction be 40-70 DEG C, such as can be 40 DEG C, 50 DEG C, 60 DEG C or
70℃。
Preferably, the number of step (2) described refluxing extraction is 1-3 times, such as can be 1 time, 2 times or 3 times.
Preferably, the time of step (2) described refluxing extraction be each 1-3 hours, such as can be 1 hour, 2 hours or
3 hours.
Preferably, the temperature of step (2) described drying is 40-70 DEG C, such as can be 40 DEG C, 50 DEG C, 60 DEG C or 70 DEG C.
Preferably, the power of step (3) ultrasound be 200-800W, such as can be 200W, 300W, 400W, 500W,
600W, 700W or 800W.
Preferably, the solid-liquid ratio of step (3) described ultrasonic extraction is 1:(10-20), such as can be 1:10、1:12、1:
14、1:16,118 or 1:20.
Preferably, the temperature of step (3) described ultrasonic extraction is 30-60 DEG C, for example, can be 30 DEG C, 35 DEG C, 40 DEG C, 45
DEG C, 50 DEG C, 55 DEG C or 60 DEG C.
Preferably, the time of step (3) described ultrasonic extraction is 20-60 minutes, for example, can be 20 minutes, 30 minutes,
40 minutes, 50 minutes or 60 minutes.
Preferably, the temperature of step (3) described concentration be 30-50 DEG C, such as can be 30 DEG C, 35 DEG C, 40 DEG C, 45 DEG C or
50℃。
The third aspect, the present invention provide a kind of method for extracting oil phase purple sesame extract as described in relation to the first aspect, including such as
Lower step：
(1 ') takes purple sesame spore, carries out brittle broken wall；
(2 ') are sieved after the conidia powder after step (1 ') broken wall is carried out ultramicro grinding broken wall；
The conidia powder that (3 ') obtain step (2 ') carries out supercritical CO2Extraction, collection obtain oil phase purple sesame extract.
Preferably, the steam pressure of step (1 ') the brittle broken wall is 0.4-0.6MPa, for example, can be 0.4MPa,
0.5MPa or 0.6MPa.
Preferably, the vapor (steam) temperature of step (1 ') the brittle broken wall is 80-100 DEG C, for example, can be 80 DEG C, 85 DEG C,
90 DEG C, 95 DEG C or 100 DEG C.
Preferably, the time of step (1 ') the brittle broken wall is 0.5-1.5 hours, such as can be 0.5 hour, 1 small
When or 1.5 hours.
Preferably, the time of step (the 2 ') ultramicro grinding be 30-60min, such as can be 30min, 35min,
40min, 45min, 50min, 55min or 60min.
Preferably, the mesh number of step (the 2 ') sieving is 80-200 mesh, such as can be 80 mesh, 90 mesh, 100 mesh, 110
Mesh, 120 mesh, 130 mesh, 140 mesh, 160 mesh, 180 mesh or 200 mesh.
Preferably, the temperature of step (the 3 ') extraction is 20-50 DEG C, such as can be 20 DEG C, 30 DEG C, 40 DEG C or 50
℃。
Preferably, the pressure of step (the 3 ') extraction be 10-30MPa, such as can be 10MPa, 15MPa, 20MPa,
25MPa or 30MPa.
Preferably, the time of step (the 3 ') extraction is 1-4 hours, such as can be 1 hour, 2 hours, 3 hours or 4
Hour.
Preferably, the collected CO of step (3 ')2Flow is 5L/h-50L/h, for example, can be 5L/h, 10L/h,
20L/h, 30L/h, 40L/h or 50L/h.
Fourth aspect, the present invention provide a kind of purple sesame extract as described in relation to the first aspect composition be used to prepare it is anti-ageing
The purposes of aging cosmetic.
5th aspect, the present invention provide a kind of cosmetics, and the cosmetics contain the extraction of purple sesame as described in relation to the first aspect
The composition of object；
Preferably, the cosmetics include any one in lotion, face cream, foundation emulsion, mildy wash, toner or BB frosts
Or at least two combination, preferably BB frost.
Currently, by ganoderma lucidum polysaccharide and ganoderma lucidum spore oil, application is actually rare with the situation in cosmetics simultaneously, and purple sesame is made
It is that aging ingredient is used for not having been reported that also in BB frost class products.The present invention selects purple sesame ingredient, by optimizing different carry
Mode is taken, extracts water-phase extract and oil-phased extract respectively, rationally compounding is prepared into BB frosts with other raw materials, of the invention
Extraction process can effectively improve the utilization rate of purple sesame raw material, hide the flaw, highlight, U.S. face while also there is apparent anti-aging effect
Fruit.
Preferably, the weight percent of the composition of purple sesame extract is 1-15% in the BB frosts, such as can be
1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14% or 15%.
Wherein, the additive amount of oil phase purple sesame extract is 0.1-3%, and the additive amount of water phase purple sesame extract is 0.5-
15%.
Preferably, the BB frosts include 5-25 parts of emollient, 5-15 parts of moisturizer, 1-5 parts of emulsifier, increasing in parts by weight
Thick dose 0.05-0.5 parts, 2-10 parts of the composition of 0.1-2 parts of stabilizer, 2-10 parts of silty class and purple sesame extract.
Preferably, the parts by weight of the emollient are 5-25 parts, for example, can be 5 parts, 7 parts, 9 parts, 11 parts, 13 parts,
15 parts, 17 parts, 19 parts, 21 parts, 23 parts or 25 parts.
Preferably, the parts by weight of the moisturizer be 5-15 parts, such as can be 5 parts, 7 parts, 9 parts, 11 parts, 13 parts or
15 parts.
Preferably, the parts by weight of the emulsifier are 1-5 parts, such as can be 1,2,3,4 or 5 part.
Preferably, the parts by weight of the thickener are 0.05-0.5 parts, for example, can be 0.05 part, 0.1 part, 0.2 part,
0.3 part, 0.4 part or 0.5 part.
Preferably, the parts by weight of the stabilizer are 0.1-2 parts, for example, can be 0.1 part, 0.2 part, 0.5 part, 0.7
Part, 0.9 part, 1 part, 1.3 parts, 1.5 parts, 1.7 parts or 2 parts.
Preferably, the parts by weight of the silty class are 2-10 parts, for example, can be 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7
Part, 8 parts, 9 parts or 10 parts.
Preferably, the parts by weight of the purple sesame extractive composition are 2-10 parts, for example, can be 2 parts, 3 parts, 4 parts, 5
Part, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts.
Preferably, the soothing oil include dormant oil, caprylic/capric triglyceride, Parleam, carbonic acid dioctyl ester,
Cetanol ethylhexoate, octyl polymethyl siloxane, isomery hexadecane, dimethyl silicone polymer, cyclomethicone,
The mixture of three kinds or more in ring five dimethyl silicone polymer or pentaerythritol tetraoctyl stearate.
Preferably, the emulsifier includes PEG-10 Polydimethylsiloxane, -2 dimerization hydroxy stearic acid ester of polyglycereol, whale
Cerul PEG/PPG-10/1 dimethyl silicone polymers, polyglyceryl-3 diisostearate, gather PEG-30 dimerization hydroxy stearic acid ester
In -2 oleate of glycerine or iso stearic acid of glycerine ester any one or at least two combination.
Preferably, the silty class include titanium dioxide, zinc oxide, mica, talcum powder, iron oxide yellow, iron oxide red or
At least four combination in iron oxide black.
Preferably, the stabilizer includes any one in magnesium sulfate, sodium chloride or magnesium stearate or at least two
Combination.
Preferably, the moisturizer includes glycerine, butanediol, dipropylene glycol, 1,3-PD, xylitol, dehydration xylose
In alcohol, glycerin polyether -26, Sodium Hyaluronate, trehalose or glycine betaine any one or at least two combination.
Preferably, the colloid raw material includes xanthans, Arabic gum natural gum, hydroxypropyl starch phosphate, carboxymethyl fibre
In dimension element, hydroxyethyl cellulose or polyacrylate cross-linked polymer -6 any one or at least two combination.
Preferably, the cosmetics further include appointing in skin conditioning agent, chelating agent, antioxidant, preservative or essence
It anticipates a kind of or at least two combinations.
Compared with prior art, the invention has the advantages that：
(1) extraction process recovery rate provided by the invention is high, can maximize components utilising the effect of purple sesame raw material, can have
Effect shortens extraction time, carries out technique productions convenient for expanding, can also reduce the use of hazardous solvent.Meanwhile entire extraction process
In be not necessarily to high temperature, avoid the destruction to active matter molecular structure because of high temperature, keep the bioactivity of purple sesame, be a kind of more satisfactory
Purple sesame novel technology for extracting, be conducive to promote and apply；
(2) by the composition of the purple sesame extract of the present invention for can effectively cover face's flaw, bright color in BB frosts；
Product can long-acting holding moisture of skin, alleviate dry skin, keep skin slip delicate；It, which also has, desalinates microgroove, restores skin bullet
Property, enhance the glossiness of skin and the senile-resistant efficacy of smoothness.
Specific implementation mode
Further to illustrate the technological means and its effect of the invention taken, below in conjunction with the preferred implementation of the present invention
Example is come the technical solution that further illustrates the present invention, but the present invention is not limited in scope of embodiments.
Embodiment 1 has the purple sesame extract I and preparation method thereof of senile-resistant efficacy
Water-phase extract
(1) it pre-processes
Purple sesame fructification is taken, impurity and sawdust are removed, is washed with deionized water only, until being dried to and be completely dried at 50 DEG C, powder
Essence crosses 80 mesh sieve, preserves for use；
(2) it extracts
Purple sesame powder is added in the ethyl alcohol that volumetric concentration is 75%, extraction solid-liquid ratio is 1:5,60 DEG C of conditions next time
Stream extraction 3 times, each 3h, centrifugation removal supernatant, is dried in vacuo under the conditions of being deposited in 50 DEG C；
By in dry purple sesame powder input deionized water, extracted with ultrasonic extraction, control ultrasonic power is 600W, is carried
Feeding liquor ratio is 1:15, Extracting temperature is 40 DEG C, and extraction time is 40 minutes；
Said extracted liquid is centrifuged into removal precipitation, merging filtrate is concentrated under reduced pressure into liquid and initial purple sesame powder at 50 DEG C
Weight ratio be 1:5, obtain the water phase purple sesame extract with senile-resistant efficacy；
2, oil-phased extract
(1) it pre-processes
Purple sesame spore is taken, is dried to and is completely dried at 50 DEG C, is preserved for use；
(2) brittle broken wall
Purple sesame spore is used into bulking equipment embrittlement broken wall, the Steam pressure control in control pressure tank is 0.4MPa, is steamed
Stripping temperature control is 80 DEG C, keeps pressure and temperature 1h, opens the valve between pressurized tank and vacuum tank, utilizes the change of moment
Temperature, pressure difference are Reishi sporule is brittle, dry；
(3) ultramicro grinding
Oneself embrittlement, dry lucidum spore powder progress ultramicro grinding broken wall 40min in pressurized tank are taken out, by the spore after crushing
Sub- powder crosses 80 mesh sieve；
(4) it extracts
Pretreated lucidum spore powder is used into supercritical CO2Extraction mode, extraction temperature are 30 DEG C, and extracting pressure is
20Mpa, extraction time are 2 hours, collect CO2Flow is 20L/h, collects gained ganoderma lucidum spore oil, obtains with anti-aging work(
The oil phase purple sesame extract of effect.
Embodiment 2 has the purple sesame extract II and preparation method thereof of senile-resistant efficacy
1, water-phase extract
(1) it pre-processes
Purple sesame fructification is taken, impurity and sawdust are removed, is washed with deionized water only, until being dried to and be completely dried at 50 DEG C, powder
Essence sieves with 100 mesh sieve, and preserves for use；
(2) it extracts
Purple sesame powder is added in the ethyl alcohol that volumetric concentration is 95%, extraction solid-liquid ratio is 1:10, under the conditions of 60 DEG C
Refluxing extraction 2 times, each 3h, centrifugation removal supernatant, is dried in vacuo under the conditions of being deposited in 50 DEG C.
By in dry purple sesame powder input deionized water, extracted with ultrasonic extraction, control ultrasonic power is 500W, is carried
Feeding liquor ratio is 1：15, Extracting temperature is 60 DEG C, and extraction time is 45 minutes；
Said extracted liquid is centrifuged into removal precipitation, merging filtrate is concentrated under reduced pressure into liquid and initial purple sesame powder at 50 DEG C
Weight ratio is 1:5, obtain the water phase purple sesame extract with senile-resistant efficacy；
2, oil-phased extract
(1) it pre-processes
Purple sesame spore is taken, is dried to and is completely dried at 50 DEG C, is preserved for use；
(2) brittle broken wall
Purple sesame spore is used into bulking equipment embrittlement broken wall, the Steam pressure control in control pressure tank is 0.6MPa, is steamed
Stripping temperature control is 100 DEG C, keeps pressure and temperature 1h, opens the valve between pressurized tank and vacuum tank, utilizes moment
Alternating temperature, pressure difference are Reishi sporule is brittle, dry；
(3) ultramicro grinding
Oneself embrittlement, dry lucidum spore powder progress ultramicro grinding broken wall 50min in pressurized tank are taken out, by the spore after crushing
Sub- powder crosses 80 mesh sieve；
(4) it extracts
Pretreated lucidum spore powder is used into supercritical CO2Extraction mode, extraction temperature are 30 DEG C, and extracting pressure is
30Mpa, extraction time are 2 hours, collect CO2Flow is 30L/h, collects gained ganoderma lucidum spore oil, obtains with anti-aging work(
The oil phase purple sesame extract of effect.
Embodiment 3 has the purple sesame extract III and preparation method thereof of senile-resistant efficacy
1, water-phase extract
(1) it pre-processes
Purple sesame fructification is taken, impurity and sawdust are removed, is washed with deionized water only, until being dried to and be completely dried at 50 DEG C, powder
Essence crosses 90 mesh sieve, preserves for use；
(2) it extracts
Purple sesame powder is added in the ethyl alcohol that volumetric concentration is 85%, extraction solid-liquid ratio is 1:6,70 DEG C of conditions next time
Stream extraction 2 times, each 2h, centrifugation removal supernatant, is dried in vacuo under the conditions of being deposited in 60 DEG C.
By in dry purple sesame powder input deionized water, extracted with ultrasonic extraction, control ultrasonic power is 600W, is carried
Feeding liquor ratio is 1:20, Extracting temperature is 60 DEG C, and extraction time is 40 minutes；
Said extracted liquid is centrifuged into removal precipitation, merging filtrate is concentrated under reduced pressure into liquid and initial purple sesame powder at 50 DEG C
Weight ratio is 1:10, obtain the water phase purple sesame extract with senile-resistant efficacy；
2, oil-phased extract
(1) it pre-processes
Purple sesame spore is taken, is dried to and is completely dried at 50 DEG C, is preserved for use；
(2) brittle broken wall
Purple sesame spore is used into bulking equipment embrittlement broken wall, the Steam pressure control in control pressure tank is 0.6MPa, is steamed
Stripping temperature control is 100 DEG C, keeps pressure and temperature 1h, opens the valve between pressurized tank and vacuum tank, utilizes moment
Alternating temperature, pressure difference are Reishi sporule is brittle, dry；
(3) ultramicro grinding
Oneself embrittlement, dry lucidum spore powder progress ultramicro grinding broken wall 30min in pressurized tank are taken out, by the spore after crushing
Sub- powder sieves with 100 mesh sieve；
(4) it extracts
Pretreated lucidum spore powder is used into supercritical CO2Extraction mode, extraction temperature are 30 DEG C, and extracting pressure is
30Mpa, extraction time are 2 hours, collect CO2Flow is 30L/h, collects gained ganoderma lucidum spore oil, obtains with anti-aging work(
The oil phase purple sesame extract of effect.
The anti-ageing BB frosts of 4 moisturizing of embodiment
A kind of formula of the anti-ageing BB frosts of moisturizing is shown in Table 1.
Table 1
Preparation method is as follows：
(1) component C is crossed into colloid mill grinding with the liquid fat of appropriate component A, emulsification is put into after making powder complete wetting
Pot；
(2) remaining component A is put into emulsification pot, is heated to 80 DEG C and is dispersed with stirring uniformly, as oil phase；
(3) B component raw material is heated to 80 DEG C of dissolvings to be uniformly dispersed, for use；
(4) B component is slowly at the uniform velocity added in oil phase under agitation, after addition, homogeneous speed 3000-
6000rpm is 3-5 minutes emulsified；
(5) 40 DEG C are cooled to, emulsification pot is added in D components, 1000~6000rpm of homogeneous speed is 1-3 minutes emulsified；
(6) it stirs evenly, vacuumizes, cool to 35 DEG C of dischargings, you can.
Embodiment 5 anti-ageing water outlet BB frosts
A kind of formula of the anti-ageing BB frosts with outlet effect is shown in Table 2.
Table 2
Preparation method is as follows：
(1) component C is crossed into colloid mill grinding with the grease of appropriate component A, emulsification pot is put into after making powder complete wetting；
(2) remaining component A is put into emulsification pot, be dispersed with stirring uniformly, as oil phase；
(3) the dissolved solution of B component raw material is uniformly dispersed, for use；
(4) B component is slowly at the uniform velocity added in oil phase under agitation, after addition, homogeneous speed 1000-
It is emulsified again under 6000rpm 3-5.0 minutes；
(5) 40 DEG C are cooled to, emulsification pot is added in D components, stirred evenly；
(6) it stirs evenly, vacuumizes, cool to 35 DEG C of dischargings, you can.
The anti-ageing BB frosts of 6 whitening of embodiment
A kind of formula of the anti-ageing BB frosts of whitening is shown in Table 3；
Table 3
Preparation method is as follows：
(1) component C is crossed into colloid mill grinding with the liquid fat of appropriate component A, emulsification is put into after making powder complete wetting
Pot；
(2) remaining component A is put into emulsification pot, is heated to 80 DEG C and is dispersed with stirring uniformly, as oil phase；
(3) B component raw material is heated to 80 DEG C of dissolvings to be uniformly dispersed, for use；
(4) B component is slowly at the uniform velocity added in oil phase under agitation, after addition, homogeneous speed 3000-
6000rpm is 3-5 minutes emulsified；
(5) 40 DEG C are cooled to, emulsification pot is added in D components, homogeneous speed 1000-6000rpm is 1-3 minutes emulsified；
(6) it stirs evenly, vacuumizes, cool to 35 DEG C of dischargings, you can.
Embodiment 7
Compared with Example 4, in addition to senile-resistant efficacy purple sesame extract I (oil phase) and with senile-resistant efficacy
Purple sesame extract I (water phase) is changed to have the purple sesame extract III (oil phase) of senile-resistant efficacy that there is the purple sesame of senile-resistant efficacy to carry
Take object III (water phase) outside, other conditions are same as Example 4.
Embodiment 8
Compared with Example 5, in addition to the additive amount of the purple sesame extract II (oil phase) with senile-resistant efficacy is changed to
0.1%, the additive amount of the purple sesame extract II (water phase) with senile-resistant efficacy is changed to outside 0.9%, other conditions and embodiment 5
It is identical.
Embodiment 9
Compared with Example 5, in addition to the additive amount of the purple sesame extract II (oil phase) with senile-resistant efficacy is changed to 3%,
The additive amount of purple sesame extract II (water phase) with senile-resistant efficacy is changed to outside 12%, and other conditions are same as Example 5.
Embodiment 10
Compared with Example 5, in addition to the additive amount of the purple sesame extract II (oil phase) with senile-resistant efficacy is changed to
0.5%, the additive amount of the purple sesame extract II (water phase) with senile-resistant efficacy is changed to outside 0.5%, other conditions and embodiment 5
It is identical.
Embodiment 11
Compared with Example 5, in addition to the additive amount of the purple sesame extract II (oil phase) with senile-resistant efficacy is changed to
0.1%, the additive amount of the purple sesame extract II (water phase) with senile-resistant efficacy is changed to outside 14.9%, other conditions and embodiment
5 is identical.
The conventional purple sesame extracting mode of comparative example 1
Water-phase extract
(1) it pre-processes
Purple sesame fructification is taken, impurity and sawdust are removed, is washed with deionized water only, until being dried to and be completely dried at 50 DEG C, powder
Essence sieves with 100 mesh sieve, and is that 95% ethyl alcohol impregnates grease removal, solid-liquid ratio 1 with volumetric concentration:1, soaking time is 2 hours, after cleaning
Drying is for use；
(2) it extracts
It is extracted using 90 DEG C of deionized waters, solid-liquid ratio 1:20, extraction time is 2 hours；
Said extracted liquid is centrifuged into removal precipitation, merging filtrate is concentrated under reduced pressure into liquid and initial purple sesame powder at 50 DEG C
Percentage is 1：5, obtain the water phase purple sesame extract with senile-resistant efficacy.
Oil-phased extract
(1) it pre-processes
Purple sesame spore is taken, is dried to and is completely dried at 50 DEG C, is preserved for use；
(2) it is acidified broken wall
Lucidum spore powder is taken to be added in a concentration of 5% hydrochloric acid, solid-liquid ratio 1:5, it is held under 80 DEG C of condition of water bath heating
Continuous stirring 1 hour, rotating speed control are 500r/min, later in -18 DEG C of quickly cooling 30min, are recycled 3 times；
(3) it extracts
Washes of absolute alcohol is used after filtering, and petroleum ether, solid-liquid ratio 1 is added in the spore of broken wall after drying:1, ultrasound is shaken
30min collected organic layers are swung, heating makes organic solvent volatilize, the oil phase purple sesame extract with senile-resistant efficacy.
Common BB frost of the comparative example 2 without containing purple sesame extract
A kind of formula of the common BB frosts without containing purple sesame extract is shown in Table 4；
Table 4
Preparation method is as follows：
(1) component C is crossed into colloid mill grinding with the liquid fat of appropriate component A, emulsification is put into after making powder complete wetting
Pot；
(2) remaining component A is put into emulsification pot, is heated to 80 DEG C and is dispersed with stirring uniformly, as oil phase；
(3) B component raw material is heated to 80 DEG C of dissolvings to be uniformly dispersed, for use；
(4) B component is slowly at the uniform velocity added in oil phase under agitation, after addition, homogeneous speed 3000-
6000rpm is 3-5 minutes emulsified；
(5) 40 DEG C are cooled to, emulsification pot is added in D components, homogeneous speed 1000-6000rpm is 1-3 minutes emulsified；
(6) it stirs evenly, vacuumizes, cool to 35 DEG C of dischargings, you can.
A kind of common whitening BB frosts without containing purple sesame extract of comparative example 3
A kind of the decline formula of BB frosts of the common whitening without containing purple sesame extract is shown in Table 5；
Table 5
Preparation method is as follows：
(1) component C is crossed into colloid mill grinding with the liquid fat of appropriate component A, emulsification is put into after making powder complete wetting
Pot；
(2) remaining component A is put into emulsification pot, is heated to 80 DEG C and is dispersed with stirring uniformly, as oil phase；
(3) B component raw material is heated to 80 DEG C of dissolvings to be uniformly dispersed, for use；
(4) B component is slowly at the uniform velocity added in oil phase under agitation, after addition, homogeneous speed 3000-
6000rpm is 3-5 minutes emulsified；
(5) 40 DEG C are cooled to, emulsification pot is added in D components, homogeneous speed 1000-6000rpm is 1-3 minutes emulsified；
(6) it stirs evenly, vacuumizes, cool to 35 DEG C of dischargings, you can.
Comparative example 4
Compared with Example 5, other than not adding water phase purple sesame extract II, other conditions are same as Example 5.
Comparative example 5
Compared with Example 5, other than not adding oil phase purple sesame extract II, other conditions are same as Example 5.
Comparative example 6
Compared with Example 5, other than the additive amount of water phase purple sesame extract II is changed to 7%, other conditions and embodiment 5
It is identical.
Comparative example 7
Compared with Example 5, other than the additive amount of oil phase purple sesame extract II is changed to 0.1%, other conditions and implementation
Example 5 is identical.
The contrast test of recovery rate
The extraction of 1.1 polysaccharide
In water-phase extract, using the content of polysaccharide as standard determination recovery rate, the measurement of purple sesame extract polysaccharide uses benzene
Phenol-Sulphuric acid colorimetry, with glucose as a standard product.
1.1.1 the preparation of standard sample solution
Precision weighs 105 DEG C of dryings to the glucose control product 100mg of constant weight, is placed in 100mL volumetric flasks, adds appropriate amount of water
Make dissolving, constant volume；Precision draws above-mentioned solution 10mL, is settled to molten to get the standard items of 100 μ g/m L in 100mL volumetric flasks
Liquid.
1.1.2 the preparation of standard curve
The Glucose standards of 0.1mL, 0.2mL, 0.3mL, 0.4mL, 0.5mL, 0.6mL, 0.7mL are pipetted with pipette precision
Product solution is respectively placed in 10mL cuvettes, and successively plus water becomes 2mL；Another plus 1.0mL 5% phenol, shakes up, rapidly
Each 5mL of the concentrated sulfuric acid is added dropwise, shakes up, in color development at room temperature 20min, with blank correction zero, its absorbance is detected at 489nm, is obtained
Regression equation y=1.17682x-0.05366, r=0.99948；
Polysaccharide extract rate (%)=measurement concentration × extension rate × extracting liquid volume/raw material dry weight × 100%；
The extraction of 1.2 triterpenes
In oil-phased extract, using the content of triterpene in purple sesame spore oil as standard determination recovery rate, using the high chlorine of vanillic aldehyde-
Triterpene content in acid colorimetric method and determined by ultraviolet spectrophotometry purple sesame spore oil；
1.2.1 solution is prepared
(1) vanillic aldehyde-glacial acetic acid solution (5%)
Vanillic aldehyde 0.5g is weighed, glacial acetic acid is added and is diluted to 10mL, dissolving；
(2) oleanolic acid reference substance solution
It accurately weighs 10mg to dry to the oleanolic acid reference substance of constant weight, methanol constant volume to 50mL shakes up, obtains 0.2mg/mL
Oleanolic acid reference substance solution, the oleanolic acid reference substance solution of 0.2mg/mL is diluted respectively, obtain 0.04mg/mL,
The oleanolic acid reference substance of 0.06mg/mL, 0.08mg/mL, 0.10mg/mL, 0.12mg/mL, 0.14mg/mL, 0.16mg/mL are molten
Liquid；
(3) purple sesame spore oil sample solution
It is accurate to weigh purple sesame spore oil 0/02g, 70 DEG C of heating water baths of absolute ethyl alcohol are added, it is cooling after it is completely dissolved
To room temperature, absolute ethyl alcohol is settled to 100mL, to be measured；
1.2.2 the preparation of standard curve
Precision draw 0.04mg/mL, 0.06mg/mL, 0.08mg/mL, 0.10mg/mL, 0.12mg/mL, 0.14mg/mL,
The oleanolic acid reference substance solution of 0.16mg/mL, normal pressure water-bath solvent evaporated；It is separately added into 5% vanillic aldehyde-glacial acetic acid solution
0.20mL, perchloric acid solution 0.8mL, be vortexed mixed hook, and 70 DEG C of heating water bath 15min are cooling.Glacial acetic acid is accurately pipetted with pipette
5.00mL dilutes, and shakes up；Using blank reagent solution as reference, using measurement extinction at spectrophotometer 545nm wavelength in 30min
Angle value (A), using triterpene content as abscissa x, absorbance is that ordinate y draws standard curve；
1.2.3 the measurement of sample size
Purple sesame spore oil sample solution 0.02g, normal pressure water-bath solvent evaporated is taken to be separately added into vanillic aldehyde-glacial acetic acid solution
0.2mL, perchloric acid solution 0.8mL, vortex mixing, 70 DEG C of heating water bath 15min cool down colorimetric, ice vinegar are accurately pipetted with pipette
Sour 5.00mL dilutions, shake up, and corresponding content is checked in from standard curve, and three cover substance in calculating ganoderma lucidum spore oil sample solution
Content；
1.3 recovery rate contrast tests
6 recovery rate contrast table of table
| Experimental example | Polysaccharide extract rate (%) | Triterpene recovery rate (%) |
| Embodiment 1 | 2.21 | 19.86 |
| Embodiment 2 | 2.33 | 20.12 |
| Embodiment 3 | 2.01 | 19.88 |
| Comparative example 1 | 0.82 | 2.47 |
6 data of table show that the purple sesame polysaccharide extract rate in the purple sesame extract (water phase) that the present invention passes through ultrasonic extraction is bright
The aobvious recovery rate higher than conventional hot water's extraction passes through embrittlement, smashing and CO2In the purple sesame extract (oil phase) of supercritical extract
Triterpene recovery rate be apparently higher than acidification broken wall, ultrasonic extraction recovery rate；The operating procedure of the present invention can effectively shorten extraction
Time carries out technique productions convenient for expanding, can also reduce the use of hazardous solvent；Meanwhile high temperature is not necessarily in entire extraction process,
The destruction to active matter molecular structure because of high temperature is avoided, the bioactivity of purple sesame is maintained, is that a kind of comparatively ideal purple sesame carries
New process is taken, is conducive to promote and apply.
Skin moisture content and skin moisture are lost in the test of (TEWL)
The preparation of 2.1 samples
Embodiment 4-11 and comparative example 2-7 totally 14 kinds of products are prepared respectively, carry out experiment below；
2.2 test equipment
The skin moisture content Corneometer tests of German Courage+Khazaka companies (German CK companies) manufacture
Instrument and the skin moisture of Courage+Khazaka companies of Germany (German CK companies) manufacture are lost in (TEWL) Tewameter
TM300 test probes；
2.3 test method
Moisture content is tested using universally acknowledgedMethod-capacitance method, the capacitance of skin
Change with the variation of water content, the water content of skin can be measured by measuring capacitance；
Moisture content of skin measurement is carried out to subject's target area skin using skin moisture measuring instrument, is made by comparing sample
The moisture-keeping efficacy of the sample is assessed with the variation of front and back and embodiment side and comparative example side moisture content of skin；
Skin moisture is lost in TEWL and is very important parameter to the function of assessing skin aging.With the aging of skin,
The water holding capacity of skin continuously decreases, the easier drying of skin, and the numerical value that skin moisture is lost in TEWL is lower.Its test philosophy
From Fick Fick'ss law of diffusion：
2.4 experiment early-stage preparations
Ripe age aging skin women 280 is chosen, the age is at 45-55 Sui；It is randomly divided into 7 groups, every group 40.Before recipient site
Any product (cosmetics or topical drug or health products for oral administration) cannot be used within 15 days；Before experiment, it is desirable that subject cleans cleaning
Facial area simultaneously enters 2221 DEG C of temperature for 2 hours after cleaning, and sit quietly 30min in the constant temperature and humidity room of humidity 5025%, and protects
Hold relaxation state；
2.5 facial area water contents and moisture loss (TEWL) efficacy assessment
Half of face test is carried out by random table in experiment, side is a kind of product, and the other side is another product, 14 kinds of productions
Product distribute to 7 groups of volunteers, and the left and right nasolabial groove part for choosing volunteer carries out skin moisture content measuring and moisture loss
(TEWL) it tests, the average value of 3 values is taken to be lost in as the data (D0) and nasolabial groove skin moisture of nasolabial groove water content
(TEWL) data (D0)；After test, volunteer need to be by that will use, and a side face smears a kind of product, and another side face is smeared
Another product；In use, smearing the right facial area using the right hand, left side facial area is smeared using left hand, forbids cross contamination
And 2 progress product smearings sooner or later daily as required, continuous on probation 28 days, and require experiment the 14th day (D14) and the 28th day
(D28) it is paid a return visit；The lighting condition of each time point should be consistent：Curtain closing, illumination appropriate；Subject lies in bed
It.The inclined angle of bed should be all consistent at every point of time；The position of bed must mark on the ground, to ensure D14
With the consistency of the position of D28；The test of the same volunteer is completed by the same survey crew.
2.6 experimental result
7 experimental results change rate unit (%) of table
It is shown by 7 data of table, the result of half face test evaluation of human body clearly can contrast embodiment 4-11 and comparison
The effect of example 2-7 difference, the face cream containing composition becomes apparent from the repair of skin moisturizing ability than blank model, can have
The increase cuticula moisture content water content of effect reduces keratoderma to extraneous moisture loss amount, promoted skin moist degree and
Smoothness, it is effective to alleviate skin aging situation.
The test of 3 skin elasticity index of test example
The preparation of 3.1 samples
With test example 2.
3.2 test equipment
Cutometer (the Cutometer@of German Courage+Khazaka companies (German CK companies) manufacture
) and skin elasticity test probe (PVM600) MPA580；
3.3 test method
Subject's target area skin carries out skin elasticity index R2, R5, R7, and as skin elasticity index parameter, (R2 is without negative
The springback capacity Ua of skin and the ratio between maximum tension amount Uf when having negative pressure when pressure；Skin in first time cyclic process when R5 is skin test
The elastic part Ur of skin recovery process and the ratio between the elastic part Ue for adding negative pressure process；It is circulated throughout for the first time when R7 is skin test
The ratio between the elastic part Ur of skin recovery process and skin maximum tension amount Uf in current cyclic process in journey), by comparing sample
Product assess improvement of the sample to skin elasticity using the variation of front and back and embodiment side and comparative example side skin elasticity index
Effect.
Test philosophy is based on suction and to stretch principle, and a negative pressure is generated by skin inspiration in tested skin surface
In one fc-specific test FC probe, it is by a contactless optic testing system that skin, which is sucked into the depth in test probe,
It measures, it is directly proportional with the depth of skin is inhaled by the ratio (emit light and receive the ratio between light) of light, thus obtain
The relation curve for the length and time that one skin is stretched；
3.4 experiment early-stage preparations
With test example 2.
The effect of 3.5 skin elasticity index, is evaluated
Half of face test is carried out by random table in experiment, side is a kind of product, and the other side is another product, chooses will
The vertical line at the outside canthus of hope person and the horizontal line crosspoint of the corners of the mouth, are measured using Cutometer, measure 3 altogether
It is secondary, take its average value as initial value (W0)；After test, volunteer need to be by that will use, and a side face smears a kind of product, separately
One side face smears another product.In use, smearing the right facial area using the right hand, left side facial area is smeared using left hand, is prohibited
Only cross contamination and as required 2 progress product smearings sooner or later daily, continuous on probation 12 weeks, and require the 1st week (W1) testing,
2nd week (W2), the 4th week (W4), the 8th week (W8) and the 12nd week (W12) is paid a return visit；The lighting condition of each time point should be kept
Unanimously：Curtain closing, illumination appropriate.Subject is in bed recumbency.The inclined angle of bed should all keep one at every point of time
It causes, the position of bed must mark on the ground, and to ensure the consistency of test position, the test of the same volunteer is by same
Survey crew completes.
3.6 experimental result
8 experiment test skin elasticity index of table changes
The test of 4 dermatoglyph depth index of test example
The preparation of 4.1 samples
With test example 2；
4.2 test equipment
(Visioline is 10. for the wrinkle of skin analyzer of German Courage+Khazaka companies (German CK companies) manufacture
VL650-Quan-tiride)；
4.3 test method
The analysis of skin lines depth and length index is carried out to subject's target area fine wrinkles model；By comparing production
Product assess the improvement effect of the sample to skin lines using the variation of front and back and real left and right sides side skin lines depth；
4.4 experiment early-stage preparations
With test example 2；
The effect of 4.5 dermatoglyph depth index, is evaluated
Fine wrinkles model first is made in canthus target area with silica gel, carrying out half of face by random table in experiment tests, and one
Side is a kind of product, and the other side is another product, is analyzed using wrinkle of skin analyzer as initial value (W0)；Test
After, volunteer need to be by that will use, and a side face smears a kind of product, and another side face smears another product；In use, using
The right hand smears the right facial area, and left side facial area is smeared using left hand, forbids cross contamination and as required 2 progress sooner or later daily
Product is smeared, continuous on probation 12 weeks, and requires the 1st week (W1) testing, the 2nd week (W2), the 4th week (W4), the 8th week (W8) and the
(W12) is paid a return visit within 12 weeks；The lighting condition of each time point should be consistent：Curtain closing, illumination appropriate.Subject exists
Bed recumbency；The inclined angle of bed should be all consistent at every point of time.The position of bed must mark on the ground, to ensure
The consistency of test position；The test of the same volunteer is completed by the same survey crew；
4.6 experimental result
9 experiment test dermatoglyph depth index of table changes
| W1 | W2 | W3 | W4 | W5 | |
| Embodiment 4 | 3.8121.08 | 3.8121.06 | 3.8021.05 | 3.7921.02 | 3.7621.02 |
| Embodiment 5 | 3.8121.12 | 3.8121.10 | 3.8021.10 | 3.7921.12 | 3.7721.42 |
| Embodiment 6 | 3.8121.13 | 3.8121.11 | 3.8021.08 | 3.7921.11 | 3.7821.01 |
| Embodiment 7 | 3.8121.10 | 3.8121.10 | 3.8021.09 | 3.7921.10 | 3.7721.03 |
| Embodiment 8 | 3.8121.05 | 3.8121.04 | 3.8021.03 | 3.7921.08 | 3.7821.12 |
| Embodiment 9 | 3.8121.04 | 3.8121.03 | 3.8021.02 | 3.7921.07 | 3.7821.11 |
| Embodiment 10 | 3.8121.10 | 3.8121.10 | 3.8021.05 | 3.7921.07 | 3.7721.20 |
| Embodiment 11 | 3.8121.10 | 3.8121.09 | 3.8021.07 | 3.7921.08 | 3.7721.01 |
| Comparative example 2 | 3.8121.07 | 3.8121.07 | 3.8121.05 | 3.8121.05 | 3.8121.03 |
| Comparative example 3 | 3.8121.07 | 3.8121.07 | 3.8121.06 | 3.8121.04 | 3.8121.05 |
| Comparative example 4 | 3.8121.08 | 3.8121.07 | 3.8121.06 | 3.8121.05 | 3.8121.03 |
| Comparative example 5 | 3.8121.08 | 3.8121.08 | 3.8121.05 | 3.8121.04 | 3.8121.05 |
| Comparative example 6 | 3.8121.07 | 3.8121.07 | 3.8121.06 | 3.8121.05 | 3.8121.03 |
| Comparative example 7 | 3.8121.08 | 3.8121.07 | 3.8121.05 | 3.8121.04 | 3.8121.02 |
It being shown according to table 8 and 9 data of table, after subject uses embodiment 4-11, skin elasticity has preferable improvement,
And with the extension of usage time, improvement enhancing, each time point before use compared with improving significantly；Skin fine wrinkles side
Face, with the extension of usage time, also have improves to a certain degree, and comparative example 2-7 is due to lacking component or proportioning over range, right
It is not improved in terms of skin elasticity and wrinkle, shows that each component is indispensable in composition, and under specific ratio range
Competence exertion superior efficacy.
5 human body evaluation test of test example
5.1 experimental method
Embodiment 4 and comparative example 2 are subjected to human body evaluation on probation, are used continuously 12 weeks, to using in sample
Skin Dryness, skin elasticity, skin shine, skin smoothness and the desalination several metrics evaluations of microgroove effect, statistics is not
Improve the number percentage of degree with service stage skin；
5.2 experimental result
Evaluation table on probation is filled according to sensory evaluation, the experiment of half face is collected and tries out evaluation table, statistical result is shown in Table 10 and table
11：
10 embodiment of table, 4 normal individual trial sensory evaluation target improvement counts (%)
| Evaluation result | Aridity | Elasticity | Glossiness | Smoothness | Microgroove |
| W1 | 36.89 | 34.34 | 66.94 | 50.94 | 5.49 |
| W4 | 66.15 | 46.58 | 80.64 | 67.28 | 9.75 |
| W8 | 83.95 | 75.64 | 89.25 | 80.76 | 15.36 |
| W12 | 92.77 | 90.57 | 95.71 | 90.63 | 20.17 |
11 comparative example of table, 2 normal individual trial sensory evaluation target improvement counts (%)
| Evaluation result | Aridity | Elasticity | Glossiness | Smoothness | Microgroove |
| W1 | 32.15 | 34.86 | 57.16 | 51.82 | 4.29 |
| W4 | 31.92 | 36.84 | 58.44 | 54.59 | 4.06 |
| W8 | 30.45 | 36.57 | 58.31 | 56.38 | 4.57 |
| W12 | 29.66 | 37.10 | 59.28 | 55.76 | 4.89 |
By the result of table 10 and table 11 as it can be seen that after using embodiment 4 the 1st week, each index of subject's self-appraisal face
(skin elasticity, glossiness, moistens degree and dermatoglyph degree of improvement at smoothness) has certain improvement, with prolonging for usage time
Long, total improvement rate of each index is gradually increased, and after 12 weeks, subject is good using feeling after product；But it compares
Example 2 does not significantly improve indices, shows effect of the BB frosts of the invention containing purple sesame extract, can long-acting holding skin
Moisture alleviates dry skin, keeps skin slip delicate；It, which also has, desalinates microgroove, restores elasticity of skin, enhances the glossiness of skin
It is similar to Example 4 with the sensory evaluation effect of the senile-resistant efficacy of smoothness, embodiment 5-11, since data volume is huge,
This is repeated no more.
In conclusion the present invention is by Optimized Extraction Process, each each condition of step is synergistic, and high efficiency extraction is fuel-displaced respectively
Phase spore oil and water phase ganoderma lucidum polysaccharide optimize the component proportion of two kinds of extracts, and mutually collaboration plays both under specific proportioning
Remarkable senile-resistant efficacy, can long-acting holding moisture of skin, alleviate dry skin, keep skin slip delicate；It, which also has, desalinates carefully
Line restores elasticity of skin, enhances the glossiness of skin and the senile-resistant efficacy of smoothness.
Applicant states that the present invention illustrates the method detailed of the present invention, but the present invention not office by above-described embodiment
It is limited to above-mentioned method detailed, that is, does not mean that the present invention has to rely on above-mentioned method detailed and could implement.Technical field
Technical staff it will be clearly understood that any improvement in the present invention, equivalence replacement and auxiliary element to each raw material of product of the present invention
Addition, the selection etc. of concrete mode, all fall within protection scope of the present invention and the open scope.
Claims (10)
1. a kind of composition of purple sesame extract, which is characterized in that the composition includes that water phase purple sesame extract and oil phase are purple
Sesame extract；
Wherein, the parts by weight of the water phase purple sesame extract are 0.5-15 parts, the parts by weight of the oil phase purple sesame extract
It is 0.1-5 parts.
2. a kind of method of extraction water phase purple sesame extract as described in claim 1, which is characterized in that include the following steps：
(1) it pre-processes：Purple sesame fructification is taken, it is for use after pulverizing and sieving；
(2) alcohol reflux：The powder that step (1) obtains is added in ethyl alcohol and carries out refluxing extraction, centrifugation is precipitated and dried；
(3) ultrasonic extraction：The powder that step (2) obtains is added to the water carry out ultrasonic extraction, filter is concentrated after centrifugation removal precipitation
Liquid to the weight ratio of filtrate and initial purple sesame powder is 1:(1-10) obtains water phase purple sesame extract.
3. according to the method described in claim 2, it is characterized in that, the mesh number of step (1) described sieving is 20-100 mesh；
Preferably, the volumetric concentration of step (2) described ethyl alcohol is 50-95%；
Preferably, the solid-liquid ratio of step (2) described refluxing extraction is 1:(1-10)；
Preferably, the temperature of step (2) described refluxing extraction is 40-70 DEG C；
Preferably, the number of step (2) described refluxing extraction is 1-3 times；
Preferably, the time of step (2) described refluxing extraction is each 1-3 hours；
Preferably, the temperature of step (2) described drying is 40-70 DEG C；
Preferably, the power of step (3) ultrasound is 200-800W；
Preferably, the solid-liquid ratio of step (3) described ultrasonic extraction is 1:(10-20)；
Preferably, the temperature of step (3) described ultrasonic extraction is 30-60 DEG C；
Preferably, the time of step (3) described ultrasonic extraction is 20-60 minutes；
Preferably, the temperature of step (3) described concentration is 30-50 DEG C.
4. a kind of method of extraction oil phase purple sesame extract as described in claim 1, which is characterized in that include the following steps：
(1 ') takes purple sesame spore, carries out brittle broken wall；
(2 ') are sieved after the conidia powder after step (1 ') broken wall is carried out ultramicro grinding broken wall；
The conidia powder that (3 ') obtain step (2 ') carries out supercritical CO2Extraction, collection obtain oil phase purple sesame extract.
5. according to the method described in claim 4, it is characterized in that, the steam pressure of step (1 ') the brittle broken wall is 0.4-
0.6MPa；
Preferably, the vapor (steam) temperature of step (1 ') the brittle broken wall is 80-100 DEG C；
Preferably, the time of step (1 ') the brittle broken wall is 0.5-1.5 hours；
Preferably, the time of step (the 2 ') ultramicro grinding is 30-60min；
Preferably, the mesh number of step (the 2 ') sieving is 80-200 mesh；
Preferably, the temperature of step (the 3 ') extraction is 20-50 DEG C；
Preferably, the pressure of step (the 3 ') extraction is 10-30MPa；
Preferably, the time of step (the 3 ') extraction is 1-4 hours；
Preferably, the collected CO of step (3 ')2Flow is 5L/h-50L/h.
6. a kind of composition of purple sesame extract as described in claim 1 is used to prepare the purposes of anti-aging cosmetics.
7. a kind of cosmetics, which is characterized in that the cosmetics contain the combination of purple sesame extract as described in claim 1
Object；
Preferably, the cosmetics include in lotion, face cream, foundation emulsion, mildy wash, toner or BB frosts any one or extremely
Few two kinds of combination, preferably BB frosts.
8. cosmetics according to claim 7, which is characterized in that the weight of the composition of purple sesame extract in the BB frosts
Percentage is 1-15%.
9. cosmetics according to claim 7 or 8, which is characterized in that the BB frosts include emollient 5- in parts by weight
25 parts, 5-15 parts of moisturizer, 1-5 parts of emulsifier, 0.05-0.5 parts of thickener, 0.1-2 parts of stabilizer, 2-10 parts of silty class and purple
2-10 parts of the composition of sesame extract.
10. cosmetics according to claim 9, which is characterized in that the soothing oil includes dormant oil, caprylic/capric glycerine
Three esters, carbonic acid dioctyl ester, cetanol ethylhexoate, octyl polymethyl siloxane, isomery hexadecane, gather Parleam
Three in dimethyl siloxane, cyclomethicone, ring five dimethyl silicone polymer or pentaerythritol tetraoctyl stearate
Kind or three kinds or more of mixture；
Preferably, the emulsifier includes PEG-10 Polydimethylsiloxane, -2 dimerization hydroxy stearic acid ester of polyglycereol, cetyl
It is PEG/PPG-10/1 dimethyl silicone polymers, PEG-30 dimerization hydroxy stearic acid ester, polyglyceryl-3 diisostearate, poly- sweet
In oily -2 oleates or iso stearic acid of glycerine ester any one or at least two combination；
Preferably, the silty class includes titanium dioxide, zinc oxide, mica, talcum powder, iron oxide yellow, iron oxide red or oxidation
At least four combination in iron oxide black；
Preferably, the stabilizer include in magnesium sulfate, sodium chloride or magnesium stearate any one or at least two combination；
Preferably, the moisturizer include glycerine, it is butanediol, dipropylene glycol, 1,3-PD, xylitol, anhydro xylitol, sweet
In oily polyethers -26, Sodium Hyaluronate, trehalose or glycine betaine any one or at least two combination；
Preferably, the colloid raw material include xanthans, Arabic gum natural gum, hydroxypropyl starch phosphate, carboxymethyl cellulose,
In hydroxyethyl cellulose or polyacrylate cross-linked polymer -6 any one or at least two combination；
Preferably, the cosmetics further include any one in skin conditioning agent, chelating agent, antioxidant, preservative or essence
Kind or at least two combination.
Priority Applications (1)
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| CN111700836A (en) * | 2020-07-24 | 2020-09-25 | 嘉文丽（福建）化妆品有限公司 | Composition capable of improving skin color and whitening skin and skin care product containing composition |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103655234A (en) * | 2013-10-12 | 2014-03-26 | 广州环亚化妆品科技有限公司 | Moisture type CC cream composition and preparation method thereof |
| CN103989619A (en) * | 2014-05-22 | 2014-08-20 | 广东省微生物研究所 | Anti-aging cream of lucid ganoderma and preparation method thereof |
| CN104650251A (en) * | 2015-01-22 | 2015-05-27 | 孙继勇 | Extraction method of mythic fungus multi-sugar alcohol |
| CN105837700A (en) * | 2016-04-12 | 2016-08-10 | 江苏江大源生态生物科技股份有限公司 | A comprehensive extraction, utilization and production method for glossy ganoderma sporocarps and spores |
| CN107308035A (en) * | 2017-06-01 | 2017-11-03 | 佛山市汇汾化妆品科技有限公司 | The beautiful skin BB frosts of one kind maintenance |
-
2018
- 2018-04-24 CN CN201810372932.7A patent/CN108379135B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103655234A (en) * | 2013-10-12 | 2014-03-26 | 广州环亚化妆品科技有限公司 | Moisture type CC cream composition and preparation method thereof |
| CN103989619A (en) * | 2014-05-22 | 2014-08-20 | 广东省微生物研究所 | Anti-aging cream of lucid ganoderma and preparation method thereof |
| CN104650251A (en) * | 2015-01-22 | 2015-05-27 | 孙继勇 | Extraction method of mythic fungus multi-sugar alcohol |
| CN105837700A (en) * | 2016-04-12 | 2016-08-10 | 江苏江大源生态生物科技股份有限公司 | A comprehensive extraction, utilization and production method for glossy ganoderma sporocarps and spores |
| CN107308035A (en) * | 2017-06-01 | 2017-11-03 | 佛山市汇汾化妆品科技有限公司 | The beautiful skin BB frosts of one kind maintenance |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111700836A (en) * | 2020-07-24 | 2020-09-25 | 嘉文丽（福建）化妆品有限公司 | Composition capable of improving skin color and whitening skin and skin care product containing composition |
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Address after: Guangzhou Science City in Guangdong province 510000 Ke Lin Lu Guangzhou high tech Industrial Development Zone No. 15 Patentee after: Guangzhou Huanya cosmetics technology Co.,Ltd. Address before: Guangzhou Science City in Guangdong province 510000 Ke Lin Lu Guangzhou high tech Industrial Development Zone No. 15 Patentee before: GUANGZHOU HUANYA COSMETICS TECHNOLOGY Co.,Ltd. |