CN108354875A - A kind of medicated toothpaste inhibiting plaque - Google Patents
A kind of medicated toothpaste inhibiting plaque Download PDFInfo
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- CN108354875A CN108354875A CN201810525866.2A CN201810525866A CN108354875A CN 108354875 A CN108354875 A CN 108354875A CN 201810525866 A CN201810525866 A CN 201810525866A CN 108354875 A CN108354875 A CN 108354875A
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- medicated toothpaste
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of medicated toothpaste, include the component of following mass percentage：0.1 10% inhibition plaque active component；20 60% rubbing agents；1 8% foaming agent；10 40% wetting agents；0.1 1% adhesive；Surplus is water；Wherein the inhibition plaque active component is mainly made of the raw material of following parts by weight：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM CYRTONEMA）1 10 parts of extract, arrow leaf orange（CITRUS HYSTRIX）1 10 parts of leaf extract.It can effectively remove the plaque of tooth, prevent periodontal disease and Proximal caries.
Description
Technical field
The present invention relates to daily necessities, and in particular to a kind of medicated toothpaste inhibiting plaque.
Background technology
Plaque belongs to a kind of biomembrane of bacterium, it is the bacillary group for the also non-mineralising for being attached on our dental surfaces
Body can not be washed out by water or gargle.If plaque accumulation is excessive, will slowly be formed thick, coarse, visible soft
Dirt, the time length after combined with the minerals in saliva, calcification is hardened to form dental calculus.Since the presence of dental calculus makes bacterial plaque and group
Intimate surface contact is knitted, the inflammatory reaction of tissue is caused.When plaque is close to gum, bacteriogenic toxin and other nuisances
Matter can stimulate gum, generate inflammation, i.e. gingivitis.If uncontrolled, develop as one pleases, gingivitis is possible to develop into can not
Inverse periodontitis causes the destruction of alveolar bone, eventually leads to tooth mobility, falls off.
With being increasingly enhanced for people's environmental consciousness, back to nature advocates green as a kind of inexorable trend and toothpaste
A kind of inevitable choice developed and produced.Invaluable experience in terms of we should inherit and develop motherland's dentistry utilizes modern skill
Art and scientific method reinforce the research of traditional Chinese medicine ingredients and therapeutic effect mechanism, and the technology of extraction active ingredient of Chinese herbs is continuously improved,
Develop more efficient, safe and non-toxic Chinese medicinal toothpaste.
Invention content
The technical problem to be solved in the present invention is to provide a kind of medicated toothpaste inhibiting plaque.
The specific technical solution for solving above-mentioned technical problem is as follows：
A kind of medicated toothpaste includes the component of following mass percentage：
（1）The inhibition plaque active component of 0.1-10%；
（2）20-60% rubbing agents；
（3）1-8% foaming agents；
（4）10-40% wetting agents；
（5）0.1-1% adhesive；
（6）Surplus is water；Wherein the inhibition plaque active component is mainly made of the raw material of following parts by weight：Ginger shape
Sealwort（POLYGONATUM CYRTONEMA）1-10 parts of extract, arrow leaf orange（CITRUS HYSTRIX）1-10 parts of leaf extract.
In wherein some embodiments, the inhibition plaque active component further includes the raw material of following parts by weight：It is hard
Rough gentian（GENTIANA RIGESCENS）1-5 parts of extract, the sharp leaf bark of ash（FRAXINUS SZABOANA）1-5 parts of extract.
Rubbing agent of the present invention is hydrated silica, calcium carbonate, calcium bicarbonate, calcium phosphate dihydrate, anhydrous calcium pyrophosphate, nothing
Any one of water calcium monohydrogen phosphate or several combinations.
Foaming agent of the present invention is C8-16 alkyl heteroside, C14-16 alkene sulfonic acid sodiums, laruyl alcohol sodium sulfovinate, coconut palm
Any one of oleamide propyl betaine, sodium lauroyl sarcosine or several combinations.
Wetting agent of the present invention is any one of sorbierite, polyethylene glycol, glycerine, propylene glycol or several groups
It closes.
Adhesive of the present invention is sodium hydroxyethyl cellulose, xanthans, carragheen, carbomer, poloxamer188, silicon
Any one of sour magnalium or several combinations.
In wherein some embodiments, the medicated toothpaste further includes preservative, the preservative be methyl hydroxybenzoate,
The additive amount of the mixture of sodium benzoate, the methyl hydroxybenzoate is 0.1-0.3wt%, and the additive amount of the sodium benzoate is 0.1-
0.3wt%。
In wherein some embodiments, the medicated toothpaste further includes 0.05-0.5wt% sweeteners, the sweetener
For any one of saccharin sodium, xylitol, antierythrite, Sucralose, Aspartame or several combinations.
The preparation method of medicated toothpaste of the present invention is easy, can be according to following operation：First, it will soak
In agent, adhesive input agitated kettle, wetting stirring adds the raw materials such as sweetener, foaming agent, water, continues to stir, fully molten
It is swollen, uniformly translucent liquid phase is made；Then, rubbing agent, antibacterial Shu Min active components, preservative etc. are put into agitated kettle, is stirred
It mixes uniformly；It is qualified to examine, and discharge filling subpackage.
The advantageous effect that technical solution provided in an embodiment of the present invention is brought is：Inhibition plaque toothpaste provided by the invention
Rich in RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM CYRTONEMA）Extract, arrow leaf orange（CITRUS HYSTRIX）Leaf extract etc. is living
Property ingredient, can effectively remove the plaque of tooth, prevent periodontal disease and Proximal caries.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Embodiment 1
A kind of toothpaste includes the component of following mass percentage：Inhibit plaque active component 0.1%, hydrated silica 10%, carbon
Sour calcium 10%, C8-16 alkyl heteroside 2%, C14-16 alkene sulfonic acid sodiums 6%, sorbierite 8%, polyethylene glycol 2%, xanthans 0.01%,
Carragheen 0.09%, methyl hydroxybenzoate 0.1%, sodium benzoate 0.3%, saccharin sodium 0.05%, surplus are water；
Wherein the inhibition plaque active component is made of the raw material of following parts by weight：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM
CYRTONEMA）1 part of extract, arrow leaf orange（CITRUS HYSTRIX）10 parts of leaf extract.
Embodiment 2
A kind of toothpaste includes the component of following mass percentage：
（1）Inhibit plaque active component 10%, hydrated silica 38%, anhydrous calcium pyrophosphate 2%, C8-16 alkyl heteroside 3.5%,
Sodium lauroyl sarcosine 1%, sorbierite 25%, sodium hydroxyethyl cellulose 0.5%, carragheen 0.5%, methyl hydroxybenzoate 0.2%, benzoic acid
Sodium 0.2%, xylitol 0.2%, surplus are water；
Wherein the inhibition plaque active component is made of the raw material of following parts by weight：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM
CYRTONEMA）10 parts of extract, arrow leaf orange（CITRUS HYSTRIX）1 part of leaf extract.
Embodiment 3
A kind of toothpaste includes the component of following mass percentage：
（1）Inhibit plaque active component 5%, hydrated silica 38%, anhydrous calcium pyrophosphate 2%, C8-16 alkyl heteroside 3.5%, the moon
Osmanthus acylsarcosine sodium 1%, sorbierite 25%, sodium hydroxyethyl cellulose 0.5%, carragheen 0.5%, methyl hydroxybenzoate 0.2%, sodium benzoate
0.2%, xylitol 0.2%, surplus are water；
Wherein the inhibition plaque active component is made of the raw material of following parts by weight：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM
CYRTONEMA）5 parts of extract, arrow leaf orange（CITRUS HYSTRIX）5 parts of leaf extract, Gentiana rigescens（GENTIANA
RIGESCENS）1 part of extract, the sharp leaf bark of ash（FRAXINUS SZABOANA）5 parts of extract.
Embodiment 4
A kind of toothpaste includes the component of following mass percentage：
（1）Inhibit plaque active component 5%, hydrated silica 38%, anhydrous calcium pyrophosphate 2%, C8-16 alkyl heteroside 3.5%, the moon
Osmanthus acylsarcosine sodium 1%, sorbierite 25%, sodium hydroxyethyl cellulose 0.5%, carragheen 0.5%, methyl hydroxybenzoate 0.2%, sodium benzoate
0.2%, xylitol 0.2%, surplus are water；
Wherein the inhibition plaque active component is made of the raw material of following parts by weight：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM
CYRTONEMA）5 parts of extract, arrow leaf orange（CITRUS HYSTRIX）5 parts of leaf extract, Gentiana rigescens（GENTIANA
RIGESCENS）5 parts of extract, the sharp leaf bark of ash（FRAXINUS SZABOANA）1 part of extract.
Embodiment 5
Toothpaste obtained by embodiment 1-4 is tested, with a commercially available toothpaste taste for laying claim to inhibition plaque effect
In addition control group 2-5 is arranged in control group 1；
Wherein control group 2 the difference from example 2 is that, inhibit plaque active component by RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM
CYRTONEMA）Extract forms；
Wherein control group 3 the difference from example 2 is that, inhibit plaque active component arrow leaf orange（CITRUS HYSTRIX）Leaf
Extract forms；
Wherein control group 4 and embodiment 4 difference lies in,
The inhibition plaque active component is made of the raw material of following parts by weight：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM
CYRTONEMA）5 parts of extract, arrow leaf orange（CITRUS HYSTRIX）5 parts of leaf extract, Gentiana rigescens（GENTIANA
RIGESCENS）5 parts of extract；
Wherein difference lies in described inhibits plaque active component by the raw material of following parts by weight to control group 5 with embodiment 4
Composition：RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM CYRTONEMA）5 parts of extract, arrow leaf orange（CITRUS HYSTRIX）Leaf extract 5
Part, the sharp leaf bark of ash（FRAXINUS SZABOANA）1 part of extract.
Test 1 volunteer test on probation
The specific test method is as follows：Each experimental group chooses 20 volunteers, there is plaque；After volunteer uses 2 weeks, root
According to personal use situation（Whether whether mild, plaque, which obtains improving, is even fully recovered）It point gives a mark from 0 to 10, finally counts
Each group overall average scoring event is denoted as consumer's scoring.Specific test result is see table 1.
1 test recording table of table
From upper table 1 as it can be seen that the toothpaste obtained by embodiment 1-2 has shared RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM CYRTONEMA）It carries
Take object, arrow leaf orange（CITRUS HYSTRIX）Mildness and plaque improvement situation will be good than commercial product after leaf extract.
Embodiment 2 and comparative example 2-3 comparisons are as it can be seen that RHIZOMA POLYGONATI ZINGIBERIFORME（POLYGONATUM CYRTONEMA）Extract, arrow leaf orange
（CITRUS HYSTRIX）Leaf extract shares better；Embodiment 4 and comparative example 4-5 comparisons are as it can be seen that Gentiana rigescens
（GENTIANA RIGESCENS）Extract, the sharp leaf bark of ash（FRAXINUS SZABOANA）Extract can be obviously improved when sharing
The mildness and plaque improvement of toothpaste obtained by the present invention.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (9)
1. a kind of medicated toothpaste, which is characterized in that include the component of following mass percentage：
（1）The inhibition plaque active component of 0.1-10%；
（2）20-60% rubbing agents；
（3）1-8% foaming agents；
（4）10-40% wetting agents；
（5）0.1-1% adhesive；
（6）Surplus is water；Wherein the inhibition plaque active component is mainly made of the raw material of following parts by weight：Ginger shape
Sealwort（POLYGONATUM CYRTONEMA）1-10 parts of extract, arrow leaf orange（CITRUS HYSTRIX）1-10 parts of leaf extract.
2. medicated toothpaste according to claim 1, which is characterized in that the inhibition plaque active component further include with
The raw material of lower parts by weight：Gentiana rigescens（GENTIANA RIGESCENS）1-5 parts of extract, the sharp leaf bark of ash（FRAXINUS
SZABOANA）1-5 parts of extract.
3. medicated toothpaste according to claim 1 or 2, which is characterized in that the rubbing agent be hydrated silica, calcium carbonate,
Any one of calcium bicarbonate, calcium phosphate dihydrate, anhydrous calcium pyrophosphate, calcium phosphate dibasic anhydrous or several combinations.
4. medicated toothpaste according to claim 1 or 2, which is characterized in that the foaming agent be C8-16 alkyl heteroside,
Any one of C14-16 alkene sulfonic acid sodiums, laruyl alcohol sodium sulfovinate, Cocoamidopropyl betaine, sodium lauroyl sarcosine or
Several combination of person.
5. medicated toothpaste according to claim 1 or 2, which is characterized in that the wetting agent be sorbierite, polyethylene glycol,
Any one of glycerine, propylene glycol or several combinations.
6. medicated toothpaste according to claim 1 or 2, which is characterized in that the adhesive is sodium hydroxyethyl cellulose, Huang
Any one of virgin rubber, carragheen, carbomer, poloxamer188, aluminum magnesium silicate or several combinations.
7. medicated toothpaste according to claim 1 or 2, which is characterized in that the medicated toothpaste further includes preservative, institute
The preservative stated is the mixture of methyl hydroxybenzoate, sodium benzoate, and the additive amount of the methyl hydroxybenzoate is 0.1-0.3wt%, the benzene
The additive amount of sodium formate is 0.1-0.3wt%.
8. medicated toothpaste according to claim 1 or 2, which is characterized in that the medicated toothpaste further includes 0.05-
0.5wt% sweeteners, the sweetener are any one of saccharin sodium, xylitol, antierythrite, Sucralose, Aspartame
Or several combination.
9. medicated toothpaste according to claim 1 or 2, which is characterized in that the preparation method of the medicated toothpaste according to
Following operation：First, by wetting agent, adhesive input agitated kettle, wetting stirring adds sweetener, foaming agent, water
Equal raw materials, continue to stir, and are fully swollen, and uniformly translucent liquid phase is made；Then, by rubbing agent, antibacterial Shu Min active components, anti-
Rotten agent etc. is put into agitated kettle, is stirred evenly；It is qualified to examine, and discharge filling subpackage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810525866.2A CN108354875A (en) | 2018-05-28 | 2018-05-28 | A kind of medicated toothpaste inhibiting plaque |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810525866.2A CN108354875A (en) | 2018-05-28 | 2018-05-28 | A kind of medicated toothpaste inhibiting plaque |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108354875A true CN108354875A (en) | 2018-08-03 |
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ID=63012552
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810525866.2A Withdrawn CN108354875A (en) | 2018-05-28 | 2018-05-28 | A kind of medicated toothpaste inhibiting plaque |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111956593A (en) * | 2020-09-22 | 2020-11-20 | 福建省梦娇兰日用化学品有限公司 | Children toothpaste containing probiotics and preparation method thereof |
-
2018
- 2018-05-28 CN CN201810525866.2A patent/CN108354875A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111956593A (en) * | 2020-09-22 | 2020-11-20 | 福建省梦娇兰日用化学品有限公司 | Children toothpaste containing probiotics and preparation method thereof |
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Application publication date: 20180803 |